Publicações
Informação sobre artigos em revista, actualizada a 28-06-2026, a partir da plataforma CIÊNCIAVITAE.
Advanced Biomaterial Strategies for Overcoming Age-associated Wound Healing Impairments
Dores, Rodrigo; Rodrigues, Telma A.; Carvalho, Daniel; Batista, Eva; Kozak, Myroslava; Blanco, Cristina; Fernandes, Hugo; Bimbo, Luís M, APL Bioengineering. 2025. under revision APL Bioengineering
miRNA-642a-3p protects ß cells from glucolipotoxicity
Pinhanços, Sandra Sofia; Teixeira de Oliveira, João; Alves, C. Henrique; Deus, Cláudia M.; de Winter, Twan J.J.; Viana, Sofia; Reis, Flávio; et al, Molecular Therapy Nucleic Acids. 2025. https://doi.org/10.1016/j.omtn.2025.102498 . 10.1016/j.omtn.2025.102498 . Molecular Therapy Nucleic Acids
Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells
Vilaça, Andreia; Jesus, Carlos; Lino, Miguel; Hayman, Danika; Emanueli, Costanza; Terracciano, Cesare M.; Fernandes, Hugo; de Windt, Leon J.; Ferreira, Lino, Molecular Therapy - Nucleic Acids. 2024. http://dx.doi.org/10.1016/j.omtn.2024.102233 . 10.1016/j.omtn.2024.102233 . accepted Molecular Therapy - Nucleic Acids
POSEIDON: Peptidic Objects SEquence-based Interaction with cellular DOmaiNs: a new database and predictor
Preto, António J.; Caniceiro, Ana B.; Duarte, Francisco; Fernandes, Hugo; Ferreira, Lino; Mourão, Joana; Moreira, Irina S., Journal of Cheminformatics. 1. 16. 2024. http://dx.doi.org/10.1186/s13321-024-00810-7 . 10.1186/s13321-024-00810-7 . Journal of Cheminformatics
TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status
Ramos Rego, Inês; Silvério, Daniela; Eufrásio, Maria Isabel; Pinhanços, Sandra Sofia; Lopes da Costa, Bruna; Teixeira, José; Fernandes, Hugo; et al, Antioxidants. 2. 12. 2023. http://dx.doi.org/10.3390/antiox12020381 . 10.3390/antiox12020381 . Antioxidants
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart
Vilaça, Andreia; de Windt, Leon J.; Fernandes, Hugo; Ferreira, Lino, Trends in Molecular Medicine. 2022. http://dx.doi.org/10.1016/j.molmed.2022.10.002 . 10.1016/j.molmed.2022.10.002 . in press Trends in Molecular Medicine
MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease
Esteves, Marta; Abreu, Ricardo; Fernandes, Hugo; Serra-Almeida, Catarina; Martins, Patrícia A.T.; Barão, Marta; Cristóvão, Ana Clara; et al, Molecular Therapy. 2022. http://dx.doi.org/10.1016/j.ymthe.2022.06.003 . 10.1016/j.ymthe.2022.06.003 . Molecular Therapy
Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration
Fernandes, Hugo; Zonnari, Alessandra; Abreu, Ricardo; Aday, Sezin; Barão, Marta; Albino, Inês; Lino, Miguel; et al, Molecular Therapy - Nucleic Acids. 307 - 327. 28. 2022. http://dx.doi.org/10.1016/j.omtn.2022.03.018 . 10.1016/j.omtn.2022.03.018 . Molecular Therapy - Nucleic Acids
Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells
Ottaviani, L.; Juni, R.P.; de Abreu, R.C.; Sansonetti, M.; Sampaio-Pinto, V.; Halkein, J.; Hegenbarth, J.C.; et al, Molecular Therapy. 2022. http://dx.doi.org/10.1016/j.ymthe.2022.03.002 . 10.1016/j.ymthe.2022.03.002 . Molecular Therapy
Exogenous loading of miRNAs into small extracellular vesicles
Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al, Journal of Extracellular Vesicles. 10. 10. 2021. http://dx.doi.org/10.1002/jev2.12111 . 10.1002/jev2.12111 . Journal of Extracellular Vesicles
High-throughput screening of nanoparticles in drug delivery
Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira, APL Bioengineering. 2021. https://doi.org/10.1063/5.0057204 . 10.1063/5.0057204 . APL Bioengineering
Native and bioengineered extracellular vesicles for cardiovascular therapeutics
de Abreu, Ricardo Cerqueira; Fernandes, Hugo; da Costa Martins, Paula A.; Sahoo, Susmita; Emanueli, Costanza; Ferreira, Lino, Nature Reviews Cardiology. 685 - 697. 11. 17. 2020. http://dx.doi.org/10.1038/s41569-020-0389-5 . 10.1038/s41569-020-0389-5 . Nature Reviews Cardiology
A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin
Pádua, Diana; Barros, Rita; Amaral, Ana Luísa; Mesquita, Patrícia; Freire, Ana Filipa; Sousa, Mafalda; Maia, André Filipe; et al, Cancers. 2. 12. 2020. http://dx.doi.org/10.3390/cancers12020495 . 10.3390/cancers12020495 . Cancers
A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies
Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino, Methods. 2020. http://dx.doi.org/10.1016/j.ymeth.2020.12.002 . 10.1016/j.ymeth.2020.12.002 . Methods
The role of ENPP1/PC-1 in osteoinduction by calcium phosphate ceramics
Othman, Ziryan; Fernandes, Hugo; Groot, Arjan J.; Luider, Theo M.; Alcinesio, Alessandro; Pereira, Daniel de Melo; Guttenplan, Alexander P.M.; Yuan, Huipin; Habibovic, Pamela, Biomaterials. 12 - 24. 210. 2019. http://dx.doi.org/10.1016/j.biomaterials.2019.04.021 . 10.1016/j.biomaterials.2019.04.021 . Biomaterials
A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity
Rosa, Susana; Pitrez, Patrícia; Fernandes, Hugo; Ferreira, Lino, Current Protocols in Stem Cell Biology. 1. 50. 2019. http://dx.doi.org/10.1002/cpsc.93 . 10.1002/cpsc.93 . Current Protocols in Stem Cell Biology
From fiber curls to mesh waves: a platform for the fabrication of hierarchically structured nanofibers mimicking natural tissue formation
Honglin Chen; Danielle F. Baptista; Giuseppe Criscenti; João Crispim; Hugo Fernandes; Clemens van Blitterswijk; Roman Truckenmüller; Lorenzo Moroni, Nanoscale. 14312 - 14321. 30. 11. 2019. https://doi.org/10.1039/C8NR10108F . 10.1039/C8NR10108F . Nanoscale
Bioactive Tape With BMP-2 Binding Peptides Captures Endogenous Growth Factors and Accelerates Healing After Anterior Cruciate Ligament Reconstruction.
Crispim JF; Fu SC; Lee YW; Fernandes HAM; Jonkheijm P; Yung PSH; Saris DBF, The American journal of sports medicine. 2018. http://europepmc.org/abstract/med/30074814 . 10.1177/0363546518787507 . The American journal of sports medicine
Soft-molecular imprinted electrospun scaffolds to mimic specific biological tissues.
Criscenti G; De Maria C; Longoni A; van Blitterswijk CA; Fernandes HAM; Vozzi G; Moroni L, Biofabrication. 2018. http://europepmc.org/abstract/med/30024388 . 10.1088/1758-5090/aad48a . Biofabrication
Muscle-Secreted Factors Improve Anterior Cruciate Ligament Graft Healing: An In Vitro and In Vivo Analysis
Ghebes, Corina Adriana; Groen, Nathalie; Cheuk, Yau Chuk; Fu, Sai Chuen; Fernandes, Hugo Machado; Saris, Daniel B.F., Tissue Engineering Part A. 322 - 334. 3-4. 24. 2018. http://dx.doi.org/10.1089/ten.tea.2016.0546 . 10.1089/ten.tea.2016.0546 . Tissue Engineering Part A
High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water
Romão, Joana; Barata, David; Ribeiro, Nelson; Habibovic, Pamela; Fernandes, Hugo; Mul, Guido, Environmental Pollution. 1199 - 1207. 220. 2017. http://dx.doi.org/10.1016/j.envpol.2016.11.015 . 10.1016/j.envpol.2016.11.015 . Environmental Pollution
Prolotherapy Induces an Inflammatory Response in Human Tenocytes In Vitro
Ekwueme, Emmanuel C.; Mohiuddin, Mahir; Yarborough, Jazmin A.; Brolinson, P. Gunnar; Docheva, Denitsa; Fernandes, Hugo A. M.; Freeman, Joseph W., Clinical Orthopaedics and Related Research®. 2117 - 2127. 8. 475. 2017. http://dx.doi.org/10.1007/s11999-017-5370-1 . 10.1007/s11999-017-5370-1 . Clinical Orthopaedics and Related Research®
High-throughput identification of small molecules that affect human embryonic vascular development.
Vazão H; Rosa S; Barata T; Costa R; Pitrez PR; Honório I; de Vries MR; et al, 2017. http://europepmc.org/abstract/med/28348206 . 10.1073/pnas.1617451114 .
TGF-ß1 activation in human hamstring cells through growth factor binding peptides on polycaprolactone surfaces
Crispim, J.; Fernandes, H.A.M.; Fu, S.C.; Lee, Y.W.; Jonkheijm, P.; Saris, D.B.F., Acta Biomaterialia. 165 - 178. 53. 2017. http://dx.doi.org/10.1016/j.actbio.2017.01.066 . 10.1016/j.actbio.2017.01.066 . Acta Biomaterialia
Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation.
Ghebes CA; Braham MV; Zeegers AV; Renard AJ; Fernandes H; Saris DB, 2016. http://europepmc.org/abstract/med/27955656 .
High-Throughput Screening Assay Identifies Small Molecules Capable of Modulating the BMP-2 and TGF-ß1 Signaling Pathway
Ghebes, Corina-Adriana; van Lente, Jéré; Post, Janine Nicole; Saris, Daniel B. F.; Fernandes, Hugo, SLAS DISCOVERY: Advancing Life Sciences R&D. 40 - 50. 1. 22. 2016. http://dx.doi.org/10.1177/1087057116669346 . 10.1177/1087057116669346 . SLAS DISCOVERY: Advancing Life Sciences R&D
Anterior cruciate ligament- and hamstring tendon-derived cells: in vitro differential properties of cells involved in ACL reconstruction
Ghebes, Corina Adriana; Kelder, Cindy; Schot, Thomas; Renard, Auke J.; Pakvis, Dean F. M.; Fernandes, Hugo; Saris, Daniel B., Journal of Tissue Engineering and Regenerative Medicine. 1077 - 1088. 4. 11. 2015. http://dx.doi.org/10.1002/term.2009 . 10.1002/term.2009 . Journal of Tissue Engineering and Regenerative Medicine
Cross-Talk Between Human Tenocytes and Bone Marrow Stromal Cells Potentiates Extracellular Matrix Remodeling In Vitro
Ekwueme, Emmanuel C.; Shah, Jay V.; Mohiuddin, Mahir; Ghebes, Corina A.; Crispim, João F.; Saris, Daniël B.F.; Fernandes, Hugo A.M.; Freeman, Joseph W., Journal of Cellular Biochemistry. 684 - 693. 3. 117. 2015. http://dx.doi.org/10.1002/jcb.25353 . 10.1002/jcb.25353 . Journal of Cellular Biochemistry
Spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo
Higuera, Gustavo A.; Fernandes, Hugo; Spitters, Tim W.G.M.; van de Peppel, Jeroen; Aufferman, Nils; Truckenmueller, Roman; Escalante, Maryana; et al, Biomaterials. 190 - 202. 61. 2015. http://dx.doi.org/10.1016/j.biomaterials.2015.05.017 . 10.1016/j.biomaterials.2015.05.017 . Biomaterials
High throughput screening assay for the identification of compounds enhancing collagenous extracellular matrix production by ATDC5 cells.
Le B; Fernandes H; Bouten C; Karperien M; van Blitterswijk C; de Boer J, 2015. http://europepmc.org/abstract/med/25604243 . 10.1089/ten.TEC.2014.0088 .
A small molecule approach to engineering vascularized tissue
Doorn, Joyce; Fernandes, Hugo A. M.; Le, Bach Q.; van de Peppel, Jeroen; van Leeuwen, Johannes P. T. M.; De Vries, Margreet R.; Aref, Zeen; et al, Biomaterials. 3053 - 3063. 12. 34. 2013. 10.1016/j.biomaterials.2012.12.037 . Biomaterials
Mesenchymal stromal cell-derived extracellular matrix influences gene expression of chondrocytes
Thakkar, Shraddha; Ghebes, Corina A.; Ahmed, Maqsood; Kelder, Cindy; van Blitterswijk, Clemens A.; Saris, Daniel; Fernandes, Hugo A. M.; Moroni, Lorenzo, Biofabrication. 2. 5. 2013. 10.1088/1758-5082/5/2/025003 . Biofabrication
Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells
Barradas, Ana M. C.; Monticone, Veronica; Hulsman, Marc; Danoux, Charlene; Fernandes, Hugo; Birgani, Zeinab Tahmasebi; Barrere-de Groot, Florence; et al, Integrative Biology. 920 - 931. 7. 5. 2013. 10.1039/c3ib40027a . Integrative Biology
A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
Barradas, Ana M.C.; Fernandes, Hugo A.M.; Groen, Nathalie; Chai, Yoke Chin; Schrooten, Jan; van de Peppel, Jeroen; van Leeuwen, Johannes P.T.M.; van Blitterswijk, Clemens A.; de Boer, Jan, Biomaterials. 3205 - 3215. 11. 33. 2012. http://dx.doi.org/10.1016/j.biomaterials.2012.01.020 . 10.1016/j.biomaterials.2012.01.020 . Biomaterials
The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice
Barradas, Ana M.C.; Yuan, Huipin; van der Stok, Johan; Le Quang, Bach; Fernandes, Hugo; Chaterjea, Anindita; Hogenes, Marieke C.H.; et al, Biomaterials. 5696 - 5705. 23. 33. 2012. http://dx.doi.org/10.1016/j.biomaterials.2012.04.021 . 10.1016/j.biomaterials.2012.04.021 . Biomaterials
Spatial distribution and survival of human and goat mesenchymal stromal cells on hydroxyapatite and ß-tricalcium phosphate.
Prins HJ; Fernandes H; Rozemuller H; van Blitterswijk C; de Boer J; Martens AC, 2012. http://europepmc.org/abstract/med/23255230 . 10.1002/term.1681 .
Endothelial Differentiation of Mesenchymal Stromal Cells
Portalska, Karolina Janeczek; Leferink, Anne; Groen, Nathalie; Fernandes, Hugo; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan, Plos One. 10. 7. 2012. 10.1371/journal.pone.0046842 . Plos One
'Smart' biomaterials and osteoinductivity
Yuan, Huipin; Fernandes, Hugo; Habibovic, Pamela; de Boer, Jan; Barradas, Ana M. C.; de Ruiter, Ad; Walsh, William R.; van Blitterswijk, Clemens A.; de Bruijn, Joost D., Nature Reviews Rheumatology. 1 - 1. 4. 7. 2011. 10.1038/nrrheum.2010.210-c1 . Nature Reviews Rheumatology
Osteoinductive ceramics as a synthetic alternative to autologous bone grafting
Yuan, Huipin; Fernandes, Hugo; Habibovic, Pamela; de Boer, Jan; Barradas, Ana M. C.; de Ruiter, Ad; Walsh, William R.; van Blitterswijk, Clemens A.; de Bruijn, Joost D., Proceedings of the National Academy of Sciences of the United States of America. 13614 - 13619. 31. 107. 2010. 10.1073/pnas.1003600107 . Proceedings of the National Academy of Sciences of the United States of America
Effect of Chordin-Like 1 on MC3T3-E1 and Human Mesenchymal Stem Cells
Fernandes, Hugo; Dechering, Koen; van Someren, Eugene; Steeghs, Ilse; Apotheker, Marion; Mentink, Anouk; van Blitterswijk, Clemens; de Boer, Jan, Cells Tissues Organs. 443 - 452. 6. 191. 2010. 10.1159/000281825 . Cells Tissues Organs
Fabrication of Bioactive Composite Scaffolds by Electrospinning for Bone Regeneration
Nandakumar, Anandkumar; Fernandes, Hugo; de Boer, Jan; Moroni, Lorenzo; Habibovic, Pamela; van Blitterswijk, Clemens A., Macromolecular Bioscience. 1365 - 1373. 11. 10. 2010. http://dx.doi.org/10.1002/mabi.201000145 . 10.1002/mabi.201000145 . Macromolecular Bioscience
In Vitro and In Vivo Bioluminescent Imaging of Hypoxia in Tissue-Engineered Grafts
Liu, Jun; Barradas, Ana; Fernandes, Hugo; Janssen, Frank; Papenburg, Bernke; Stamatialis, Dimitrios; Martens, Anton; van Blitterswijk, Clemens; de Boer, Jan, Tissue Engineering Part C-Methods. 479 - 485. 3. 16. 2010. 10.1089/ten.tec.2009.0278 . Tissue Engineering Part C-Methods
In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering
Teixeira, S.; Fernandes, H.; Leusink, A.; van Blitterswijk, C.; Ferraz, M. P.; Monteiro, F. J.; de Boer, J., Journal of Biomedical Materials Research Part a. 567 - 575. 2. 93A. 2010. 10.1002/jbm.a.32532 . Journal of Biomedical Materials Research Part a
Endogenous Collagen Influences Differentiation of Human Multipotent Mesenchymal Stromal Cells
Fernandes, Hugo; Mentink, Anouk; Bank, Ruud; Stoop, Reinout; van Blitterswijk, Clemens; de Boer, Jan, Tissue Engineering Part a. 1693 - 1702. 5. 16. 2010. 10.1089/ten.tea.2009.0341 . Tissue Engineering Part a
cAMP/PKA Signaling Inhibits Osteogenic Differentiation and Bone Formation in Rodent Models
Siddappa, Ramakrishnaiah; Mulder, Winfried; Steeghs, Ilse; van de Klundert, Christine; Fernandes, Hugo; Liu, Jun; Arends, Roel; van Blitterswijk, Clemens; de Boer, Jan, Tissue Engineering Part A. 2135 - 2143. 8. 15. 2009. http://dx.doi.org/10.1089/ten.tea.2008.0512 . 10.1089/ten.tea.2008.0512 . Tissue Engineering Part A
Extracellular matrix and tissue engineering applications
Fernandes, Hugo; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan, Journal of Materials Chemistry. 5474 - 5484. 31. 19. 2009. 10.1039/b822177d . Journal of Materials Chemistry
Growth, Metabolism, and Growth Inhibitors of Mesenchymal Stem Cells
Schop, Deborah; Janssen, Frank W.; van Rijn, Linda D.S.; Fernandes, Hugo; Bloem, Rolf M.; de Bruijn, Joost D.; van Dijkhuizen-Radersma, Riemke, Tissue Engineering Part A. 1877 - 1886. 8. 15. 2009. http://dx.doi.org/10.1089/ten.tea.2008.0345 . 10.1089/ten.tea.2008.0345 . Tissue Engineering Part A
The Role of Collagen Crosslinking in Differentiation of Human Mesenchymal Stem Cells and MC3T3-E1 Cells
Fernandes, Hugo; Dechering, Koen; Van Someren, Eugene; Steeghs, Ilse; Apotheker, Marion; Leusink, Anouk; Bank, Ruud; et al, Tissue Engineering Part A. 3857 - 3867. 12. 15. 2009. http://dx.doi.org/10.1089/ten.tea.2009.0011 . 10.1089/ten.tea.2009.0011 . Tissue Engineering Part A
The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering.
Siddappa, Ramakrishnaiah; Fernandes, Hugo; Liu, Jun; van Blitterswijk, Clemens; de Boer, Jan, Current stem cell research & therapy. 209 - 20. 3. 2. 2007. 10.2174/157488807781696267 . Current stem cell research & therapy
Mesenchymal stem cell proliferation and morphological analysis on interconnected macroporous structures
Teixeira, S.; Fernandes, H.M.; De Boer, J.; Ferraz, M.P.; Monteiro, F.J., Key Engineering Materials. 1129 - 1132. 330-332 II. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846317063&partnerID=MN8TOARS . Key Engineering Materials
5 50 de 50 Publicações
Todos os projectos
Informação da exclusiva responsabilidade do investigador 28-06-2026 , a partir da plataforma CIÊNCIAVITAE.
2023/03 -
miRNA-engineered EVs for the treatment of diabetic wounds
NA
Principal investigator
Financiadores: Sociedade Portuguesa de Diabetologia
2022/07/01 - 2023/06/30
BIO-MED: Biomolecular Engineering of extracellular vesicles for Regenerative Medicine
AAC nº01/SAICT/2021 - Project #181228
Co-Principal Investigator (Co-PI)
Financiadores: Programa Operacional Regional do Centro
2021/11 - 2023/04
EV-Heart: cardioprotection and regeneration mediated by systemic administration of targeted miRNA-modulated extracellular vesicles
CEECIND/01880/2018
Researcher
Universidade de Coimbra Faculdade de Medicina
Financiadores: Fundação para a Ciência e a Tecnologia, I.P.
2018/08 - 2021/08
Exo-Heart: cardiac protection and regeneration mediated by systemic administration of targeted exosomes
029919
Financiadores: Fundação para a Ciência e a Tecnologia
2017/06/01 - 2021/06/01
Towards personalized beta-cell mass imaging in type 2 Diabetes
95105008
Integration into Research Grant Fellow
ZonMw
Financiadores: ZonMw
2015/07/01 -
Role of microRNAs in chondrogenesis of human mesenchymal stromal cells
TAS Breakthrough #116005004
Integration into Research Grant Fellow
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
2015/07/01 -
Role of microRNAs in chondrogenesis of human mesenchymal stromal cells
NA
Integration into Research Grant Fellow
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
2013/07 - 2015/06
Combinatorial approaches to promote cell survival - PROSURVIVAL
125994
Financiadores: Fundação para a Ciência e a Tecnologia, I.P.
2012/02/01 - 2016/02/01
Advanced Tendon and Ligament Healing
NA
Principal investigator
Smith & Nephew
5 9 de 9 projetos
Este website utiliza cookies para melhorar a sua experiência.
