Publicações
Informação sobre artigos em revista, actualizada a 22-06-2025, a partir da plataforma CIÊNCIAVITAE.
Adenosine A2A receptots modulate generalization of contextual fear in rats.
Simões, Ana; Portes, Marina; Silva, Henrique B.; Pliássova, Anna; Lourenço, Vanessa; Cunha, Rodrigo A.; Canas, Paula M.; Prediger, Rui D., Neuropharmacology. 2022. submitted Neuropharmacology
Purinergic signaling orchestrating neuron-glia communication
Agostinho, Paula; Canas, Paula M.; Madeira, Daniela; Dias, Liliana; Simões, Ana; Cunha, Rodrigo A., Pharmacological Research. 162. 2020. published Pharmacological Research
Adenosine A 1 and A 2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus
Reis, Sara L.; Silva, Henrique B.; Almeida, Margarida; Cunha, Rodrigo A.; Simões, Ana P.; Canas, Paula M., Journal of Neurochemistry. 227 - 237. 2. 151. 2019. http://dx.doi.org/10.1111/jnc.14816 . 10.1111/jnc.14816 . published Journal of Neurochemistry
Adenosine A2A receptors modulate the dopamine D2 receptor-mediated inhibition of synaptic transmission in the mouse prefrontal cortex
Real, Joana I.; Simões, Ana Patrícia; Cunha, Rodrigo A.; Ferreira, Samira G.; Rial, Daniel, European Journal of Neuroscience. 1127 - 1134. 9. 47. 2018. http://dx.doi.org/10.1111/ejn.13912 . 10.1111/ejn.13912 . published European Journal of Neuroscience
Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation
Simões, Ana P.; Silva, Carla G.; Marques, Joana M.; Pochmann, Daniela; Porciúncula, Lisiane O.; Ferreira, Sofia; Oses, Jean P.; et al, Cell Death & Disease. 3. 9. 2018. http://dx.doi.org/10.1038/s41419-018-0351-1 . 10.1038/s41419-018-0351-1 . published Cell Death & Disease
Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions
Canas, Paula M.; Porciúncula, Lisiane O.; Simões, Ana Patrícia; Augusto, Elisabete; Silva, Henrique B.; Machado, Nuno J.; Gonçalves, Nélio; et al, eneuro. ENEURO.0385 - 18.2018. 6. 5. 2018. http://dx.doi.org/10.1523/eneuro.0385-18.2018 . 10.1523/eneuro.0385-18.2018 . published eneuro
Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses
Machado, Nuno J.; Simões, Ana Patrícia; Silva, Henrique B.; Ardais, Ana Paula; Kaster, Manuella P.; Garção, Pedro; Rodrigues, Diana I.; et al, Molecular Neurobiology. 1552 - 1563. 2. 54. 2017. http://dx.doi.org/10.1007/s12035-016-9774-9 . 10.1007/s12035-016-9774-9 . published Molecular Neurobiology
Adenosine A2A Receptors in the Amygdala Control Synaptic Plasticity and Contextual Fear Memory
Simões, Ana Patrícia; Machado, Nuno J; Gonçalves, Nélio; Kaster, Manuella P; Simões, Ana T; Nunes, Ana; Pereira de Almeida, Luís; et al, Neuropsychopharmacology. 2862 - 2871. 12. 41. 2016. http://dx.doi.org/10.1038/npp.2016.98 . 10.1038/npp.2016.98 . published Neuropsychopharmacology
ATP P2Y1 receptors control cognitive deficits and neurotoxicity but not glial modifications induced by brain ischemia in mice
Carmo, Marta R. S.; Simões, Ana Patrícia; Fonteles, Analu A.; Souza, Carolina M.; Cunha, Rodrigo A.; Andrade, Geanne M., European Journal of Neuroscience. 614 - 622. 4. 39. 2014. http://dx.doi.org/10.1111/ejn.12435 . 10.1111/ejn.12435 . published European Journal of Neuroscience
Predominant loss of glutamatergic terminal markers in a ß-amyloid peptide model of Alzheimer's disease
Canas, Paula M.; Simões, Ana Patrícia; Rodrigues, Ricardo J.; Cunha, Rodrigo A., Neuropharmacology. 51 - 56. 76. 2014. http://dx.doi.org/10.1016/j.neuropharm.2013.08.026 . 10.1016/j.neuropharm.2013.08.026 . published Neuropharmacology
Blockade of adenosine A2A receptors prevents interleukin-1ß-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway
Simões, Ana Patrícia; Duarte, João A; Agasse, Fabienne; Canas, Paula Margarida; Tomé, Angelo R; Agostinho, Paula; Cunha, Rodrigo A, Journal of Neuroinflammation. 1. 9. 2012. http://dx.doi.org/10.1186/1742-2094-9-204 . 10.1186/1742-2094-9-204 . published Journal of Neuroinflammation
Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction
Rebola, Nelson; Simões, Ana Patrícia; Canas, Paula M.; Tomé, Angelo R.; Andrade, Geanne M.; Barry, Claire E.; Agostinho, Paula M.; Lynch, Marina A.; Cunha, Rodrigo A., Journal of Neurochemistry. 100 - 111. 1. 117. 2011. http://dx.doi.org/10.1111/j.1471-4159.2011.07178.x . 10.1111/j.1471-4159.2011.07178.x . published Journal of Neurochemistry
Key Modulatory Role of Presynaptic Adenosine A2AReceptors in Cortical Neurotransmission to the Striatal Direct Pathway
Quiroz, César; Luján, Rafael; Uchigashima, Motokazu; Simoes, Ana Patrícia; Lerner, Talia N.; Borycz, Janusz; Kachroo, Anil; et al, The Scientific World JOURNAL. 1321 - 1344. 9. 2009. http://dx.doi.org/10.1100/tsw.2009.143 . 10.1100/tsw.2009.143 . published The Scientific World JOURNAL
GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A2A receptors
Gomes, Catarina A. R. V.; Simões, Patrícia F.; Canas, Paula M.; Quiroz, César; Sebastião, Ana M.; Ferré, Sergi; Cunha, Rodrigo A.; Ribeiro, Joaquim A., Journal of Neurochemistry. 1208 - 1219. 5. 108. 2009. http://dx.doi.org/10.1111/j.1471-4159.2009.05876.x . 10.1111/j.1471-4159.2009.05876.x . published Journal of Neurochemistry
Methamphetamine Changes NMDA and AMPA Glutamate Receptor Subunit Levels in the Rat Striatum and Frontal Cortex
Simões, Patrícia F.; Silva, Ana P.; Pereira, Frederico C.; Marques, Elsa; Milhazes, Nuno; Borges, Fernanda; Ribeiro, Carlos F.; Macedo, Tice R., Annals of the New York Academy of Sciences. 232 - 241. 1. 1139. 2008. http://dx.doi.org/10.1196/annals.1432.028 . 10.1196/annals.1432.028 . published Annals of the New York Academy of Sciences
Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory
Simões, P.F.; Silva, A.P.; Pereira, F.C.; Marques, E.; Grade, S.; Milhazes, N.; Borges, F.; Ribeiro, C.F.; Macedo, T.R., Neuroscience. 433 - 441. 2. 150. 2007. http://dx.doi.org/10.1016/j.neuroscience.2007.09.044 . 10.1016/j.neuroscience.2007.09.044 . published Neuroscience
Activity and expression of a virulence factor, gelatinase, in dairy enterococci
Lopes, Maria de Fátima Silva; Simões, Ana Patrícia; Tenreiro, Rogério; Marques, José Joaquim Figueiredo; Crespo, Maria Teresa Barreto, International Journal of Food Microbiology. 208 - 214. 3. 112. 2006. http://dx.doi.org/10.1016/j.ijfoodmicro.2006.09.004 . 10.1016/j.ijfoodmicro.2006.09.004 . published International Journal of Food Microbiology
5 17 de 17 Publicações
Todos os projectos
Informação da exclusiva responsabilidade do investigador 22-06-2025 , a partir da plataforma CIÊNCIAVITAE.
2019/10 - 2021/09
Adenosine A2A receptors as an opportunity to manage and detail the neurobiology of emotional distress
Fundacion La Caixa 2019
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Obra Social La Caixa
2018/07 - 2021/06
Adenosine A2A receptors as triggers of memory dysfunction in Alzheimer's disease: mechanisms and therapeutic prospects
PAS/31274
Post-doc Fellow
Financiadores: Comissão de Coordenação e Desenvolvimento Regional do Centro
2017 - 2018
Study of caffeine derivatives in the inhibition of Alzheimer's disease and as the basis to develop new therapeutics agents
Maratona da Saúde 2017
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2016/05 - 2018/06
Role of astrocytes in the control of memory- focus on adenosine A2A receptors
PTDC/NEU-NMC/4154/2014
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2015/01 - 2017/06
The up-regulation of hippocampal adenosine A2A receptors is necessary and sufficient to trigger memory dysfunction in Alzheimer's disease
MB-98-2014
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Santa Casa da Misericórdia de Lisboa
2014/09 - 2016/08
Role of adenosine A2A receptors in different brain circuits differently impact on reward and fear
NARSAD Independent Investigator Grant
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Brain and Behavior Research Foundation
2014 - 2015
Transcriptome, epigenome and proteome dysregulation in human circuits regulating reward, fear and habit learning
DARPA-BAA-10-55
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Defense Advanced Research Projects Agency
2014 - 2016
New treatments for stress-induced dysregulation of circuits regulating reward, fear and habit learning
DARPA-09-68-ESR-FP-010
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Defense Advanced Research Projects Agency
2012/04 - 2014/09
Role of accumbens and amygdala in the control of chronic stress neuropathology
grant.Provided by PTCRIS: 122254
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2010/03 - 2012/09
Role of ATP and its P2Y1 receptors in neuroprotection
grant.Provided by PTCRIS: 100423
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2010/03 - 2012/02
Role of adenosine A2A receptors in microglia and glutamatergic synapses in the control of synaptic plasticity and brain damage
grant.Provided by PTCRIS: 108668
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2007/05 - 2010/04
Interaction between nicotine and caffeine in the striatum. Relevance for Parkinson´s disease
grant.Provided by PTCRIS: 81064
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2007/06 - 2009/08
Role of extracellular ATP and characterization of purinergic receptors in the resistance of Candida albicans to macrophage attack
grant.Provided by PTCRIS: 81436
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2007/07 - 2009/10
Effect of purines in the developing hippocampus: consequences for the establishement of circuits related to learning and memory
grant.Provided by PTCRIS: 74318
PhD Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
5 14 de 14 projetos
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