Ana Patrícia Figueiredo Rocha Simões

Team icon

Researcher

Publications

Show less

Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.

Purinergic signaling orchestrating neuron-glia communication

Agostinho, Paula; Canas, Paula M.; Madeira, Daniela; Dias, Liliana; Simões, Ana; Cunha, Rodrigo A., Pharmacological Research. 162. 2020. published Pharmacological Research

Adenosine A 1 and A 2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus

Reis, Sara L.; Silva, Henrique B.; Almeida, Margarida; Cunha, Rodrigo A.; Simões, Ana P.; Canas, Paula M., Journal of Neurochemistry. 227 - 237. 2. 151. 2019. http://dx.doi.org/10.1111/jnc.14816 . 10.1111/jnc.14816 . published Journal of Neurochemistry

Adenosine A2A receptors modulate the dopamine D2 receptor-mediated inhibition of synaptic transmission in the mouse prefrontal cortex

Real, Joana I.; Simões, Ana Patrícia; Cunha, Rodrigo A.; Ferreira, Samira G.; Rial, Daniel, European Journal of Neuroscience. 1127 - 1134. 9. 47. 2018. http://dx.doi.org/10.1111/ejn.13912 . 10.1111/ejn.13912 . published European Journal of Neuroscience

Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation

Simões, Ana P.; Silva, Carla G.; Marques, Joana M.; Pochmann, Daniela; Porciúncula, Lisiane O.; Ferreira, Sofia; Oses, Jean P.; et al, Cell Death & Disease. 3. 9. 2018. http://dx.doi.org/10.1038/s41419-018-0351-1 . 10.1038/s41419-018-0351-1 . published Cell Death & Disease

Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions

Canas, Paula M.; Porciúncula, Lisiane O.; Simões, Ana Patrícia; Augusto, Elisabete; Silva, Henrique B.; Machado, Nuno J.; Gonçalves, Nélio; et al, eneuro. ENEURO.0385 - 18.2018. 6. 5. 2018. http://dx.doi.org/10.1523/eneuro.0385-18.2018 . 10.1523/eneuro.0385-18.2018 . published eneuro

Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses

Machado, Nuno J.; Simões, Ana Patrícia; Silva, Henrique B.; Ardais, Ana Paula; Kaster, Manuella P.; Garção, Pedro; Rodrigues, Diana I.; et al, Molecular Neurobiology. 1552 - 1563. 2. 54. 2017. http://dx.doi.org/10.1007/s12035-016-9774-9 . 10.1007/s12035-016-9774-9 . published Molecular Neurobiology

Adenosine A2A Receptors in the Amygdala Control Synaptic Plasticity and Contextual Fear Memory

Simões, Ana Patrícia; Machado, Nuno J; Gonçalves, Nélio; Kaster, Manuella P; Simões, Ana T; Nunes, Ana; Pereira de Almeida, Luís; et al, Neuropsychopharmacology. 2862 - 2871. 12. 41. 2016. http://dx.doi.org/10.1038/npp.2016.98 . 10.1038/npp.2016.98 . published Neuropsychopharmacology

Predominant loss of glutamatergic terminal markers in a ß-amyloid peptide model of Alzheimer's disease

Canas, Paula M.; Simões, Ana Patrícia; Rodrigues, Ricardo J.; Cunha, Rodrigo A., Neuropharmacology. 51 - 56. 76. 2014. http://dx.doi.org/10.1016/j.neuropharm.2013.08.026 . 10.1016/j.neuropharm.2013.08.026 . published Neuropharmacology

ATP P2Y1 receptors control cognitive deficits and neurotoxicity but not glial modifications induced by brain ischemia in mice

Carmo, Marta R. S.; Simões, Ana Patrícia; Fonteles, Analu A.; Souza, Carolina M.; Cunha, Rodrigo A.; Andrade, Geanne M., European Journal of Neuroscience. 614 - 622. 4. 39. 2014. http://dx.doi.org/10.1111/ejn.12435 . 10.1111/ejn.12435 . published European Journal of Neuroscience

Blockade of adenosine A2A receptors prevents interleukin-1ß-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway

Simões, Ana Patrícia; Duarte, João A; Agasse, Fabienne; Canas, Paula Margarida; Tomé, Angelo R; Agostinho, Paula; Cunha, Rodrigo A, Journal of Neuroinflammation. 1. 9. 2012. http://dx.doi.org/10.1186/1742-2094-9-204 . 10.1186/1742-2094-9-204 . published Journal of Neuroinflammation

Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction

Rebola, Nelson; Simões, Ana Patrícia; Canas, Paula M.; Tomé, Angelo R.; Andrade, Geanne M.; Barry, Claire E.; Agostinho, Paula M.; Lynch, Marina A.; Cunha, Rodrigo A., Journal of Neurochemistry. 100 - 111. 1. 117. 2011. http://dx.doi.org/10.1111/j.1471-4159.2011.07178.x . 10.1111/j.1471-4159.2011.07178.x . published Journal of Neurochemistry

GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A2A receptors

Gomes, Catarina A. R. V.; Simões, Patrícia F.; Canas, Paula M.; Quiroz, César; Sebastião, Ana M.; Ferré, Sergi; Cunha, Rodrigo A.; Ribeiro, Joaquim A., Journal of Neurochemistry. 1208 - 1219. 5. 108. 2009. http://dx.doi.org/10.1111/j.1471-4159.2009.05876.x . 10.1111/j.1471-4159.2009.05876.x . published Journal of Neurochemistry

Key Modulatory Role of Presynaptic Adenosine A2AReceptors in Cortical Neurotransmission to the Striatal Direct Pathway

Quiroz, César; Luján, Rafael; Uchigashima, Motokazu; Simoes, Ana Patrícia; Lerner, Talia N.; Borycz, Janusz; Kachroo, Anil; et al, The Scientific World JOURNAL. 1321 - 1344. 9. 2009. http://dx.doi.org/10.1100/tsw.2009.143 . 10.1100/tsw.2009.143 . published The Scientific World JOURNAL

Methamphetamine Changes NMDA and AMPA Glutamate Receptor Subunit Levels in the Rat Striatum and Frontal Cortex

Simões, Patrícia F.; Silva, Ana P.; Pereira, Frederico C.; Marques, Elsa; Milhazes, Nuno; Borges, Fernanda; Ribeiro, Carlos F.; Macedo, Tice R., Annals of the New York Academy of Sciences. 232 - 241. 1. 1139. 2008. http://dx.doi.org/10.1196/annals.1432.028 . 10.1196/annals.1432.028 . published Annals of the New York Academy of Sciences

Methamphetamine induces alterations on hippocampal NMDA and AMPA receptor subunit levels and impairs spatial working memory

Simões, P.F.; Silva, A.P.; Pereira, F.C.; Marques, E.; Grade, S.; Milhazes, N.; Borges, F.; Ribeiro, C.F.; Macedo, T.R., Neuroscience. 433 - 441. 2. 150. 2007. http://dx.doi.org/10.1016/j.neuroscience.2007.09.044 . 10.1016/j.neuroscience.2007.09.044 . published Neuroscience

Activity and expression of a virulence factor, gelatinase, in dairy enterococci

Lopes, Maria de Fátima Silva; Simões, Ana Patrícia; Tenreiro, Rogério; Marques, José Joaquim Figueiredo; Crespo, Maria Teresa Barreto, International Journal of Food Microbiology. 208 - 214. 3. 112. 2006. http://dx.doi.org/10.1016/j.ijfoodmicro.2006.09.004 . 10.1016/j.ijfoodmicro.2006.09.004 . published International Journal of Food Microbiology

All projects

Show less

Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.

2019/10 - 2021/09

Adenosine A2A receptors as an opportunity to manage and detail the neurobiology of emotional distress

Fundacion La Caixa 2019

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Obra Social La Caixa

2018/07 - 2021/06

Adenosine A2A receptors as triggers of memory dysfunction in Alzheimer's disease: mechanisms and therapeutic prospects

PAS/31274

Post-doc Fellow

Funders: Comissão de Coordenação e Desenvolvimento Regional do Centro

2017 - 2018

Study of caffeine derivatives in the inhibition of Alzheimer's disease and as the basis to develop new therapeutics agents

Maratona da Saúde 2017

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2016/05 - 2018/06

Role of astrocytes in the control of memory- focus on adenosine A2A receptors

PTDC/NEU-NMC/4154/2014

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2015/01 - 2017/06

The up-regulation of hippocampal adenosine A2A receptors is necessary and sufficient to trigger memory dysfunction in Alzheimer's disease

MB-98-2014

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Santa Casa da Misericórdia de Lisboa

2014/09 - 2016/08

Role of adenosine A2A receptors in different brain circuits differently impact on reward and fear

NARSAD Independent Investigator Grant

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Brain and Behavior Research Foundation

2014 - 2015

Transcriptome, epigenome and proteome dysregulation in human circuits regulating reward, fear and habit learning

DARPA-BAA-10-55

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Defense Advanced Research Projects Agency

2014 - 2016

New treatments for stress-induced dysregulation of circuits regulating reward, fear and habit learning

DARPA-09-68-ESR-FP-010

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Defense Advanced Research Projects Agency

2012/04 - 2014/09

Role of accumbens and amygdala in the control of chronic stress neuropathology

grant.Provided by PTCRIS: 122254

Post-doc Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03 - 2012/09

Role of ATP and its P2Y1 receptors in neuroprotection

grant.Provided by PTCRIS: 100423

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03 - 2012/02

Role of adenosine A2A receptors in microglia and glutamatergic synapses in the control of synaptic plasticity and brain damage

grant.Provided by PTCRIS: 108668

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2007/05 - 2010/04

Interaction between nicotine and caffeine in the striatum. Relevance for Parkinson´s disease

grant.Provided by PTCRIS: 81064

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2007/06 - 2009/08

Role of extracellular ATP and characterization of purinergic receptors in the resistance of Candida albicans to macrophage attack

grant.Provided by PTCRIS: 81436

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2007/07 - 2009/10

EFFECT OF PURINES IN THE DEVELOPING HIPPOCAMPUS: CONSEQUENCES FOR THE ESTABLISHMENT OF CIRCUITS RELATED TO LEARNING AND MEMORY

grant.Provided by PTCRIS: 74318

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

We use cookies to improve your visit to our website.