CNC

Visão Geral

Luis Maria Bimbo (luis.bimbo@cnc.uc.pt) is an Assistant Professor in Pharmaceutical Technology at the University of Coimbra Portugal, an Adjunct Professor in Pharmaceutical Nanotechnology at the University of Helsinki, Finland, and a Researcher at the Centre for Neuroscience and Cell Biology, University of Coimbra, Portugal. He graduated in Pharmaceutical Sciences at the University of Coimbra, Portugal and completed an MRes in Cell Biology at the same University. He then undertook a PhD in Pharmaceutical Technology at the University of Helsinki, Finland, defending his thesis (with Distinction) on the biocompatibility and biodistribution of porous silicon particles. After his PhD defence, Luis M. Bimbo was awarded a personal Fellowship from the Finnish Cultural Foundation (03.2012-12.2013) which enabled him to independently support his postdoctoral research at the University of Helsinki. On January 2014, Luis M. Bimbo received major research funding from the Jane and Aatos Erkko Foundation (1.2014-8.2015) to further support his postdoctoral research at the University of Helsinki, Finland dealing with supramolecular structures as cellular reactors for in-situ drug delivery. Subsequently, Luis M. Bimbo competitively won a personal Academy of Finland Postdoctoral Researcher (09.2015-12.2016) position from Finland’s main funding body, which had a 12% success rate for the Postdoctoral Researchers’ position when Luis M. Bimbo received his funding, to study amphiphilic dendrimers as drug carriers and surfactants. On January 2017 he moved to the UK when awarded a highly competitive tenure-track fellowship named “Chancellor’s Research Fellowship” from the University of Strathclyde, and was appointed as a Lecturer (Assistant Professor) in Drug Delivery (01.2017-08.2020) at the Strathclyde Institute of Pharmacy and Biomedical Sciences. Luis M. Bimbo research interests are focused on Pharmaceutics and Drug Delivery; more specifically he leads a research group investigating porous materials for pharmaceutical processing, supramolecular hydrogels, drug nanocrystals, and lung delivery, which so far attracted over €537 780 in external funding as a PI and resulted in 22 original peer-reviewed publications in high-impact journals, such as ACS Nano (2), Biomaterials (3), Nanoscale (2) and Journal of Controlled Release (1), which garnered 2364 citations. He has h-index of 21 (Google Scholar). Luis M. Bimbo has received several awards for his research contributions, both at national and international level, such as the Albert Wuokko Award to a Young Researcher by the Finnish Pharmaceutical Society (a competitive national biennial award which is Finland’s most prestigious pharmaceutical award bestowed to a young pharmaceutical scientist), the Best Thesis Award by the Viikki Research Groups Organization (a competitive national annual award given to the best thesis in all Biosciences except Medicine at the University of Helsinki), the Award for the Most Outstanding Doctoral Thesis in the Pharmaceutical Sciences by the APV (a competitive international biennial award for the best thesis in Pharmaceutical Technology by the International Association for Pharmaceutical Technology) and the Emerging Scientist Award from the Academy of Pharmaceutical Sciences of the United Kingdom, UK (a competitive personal award which recognises researchers from across the globe in academia, industry, public service or other scientific establishments with no more than 10 years since award of their PhD, have an outstanding track record indicative of excellent potential).

Afiliação

Faculdade de Farmácia, Universidade de Coimbra, PORTUGAL

Publicações

Informação sobre artigos em revista, actualizada a 15-09-2024, a partir da plataforma CIÊNCIAVITAE.

Functionalising silk hydrogels with hetero- and homotypic nanoparticles

Jirada Kaewchuchuen; Saphia A. L. Matthew; Suttinee Phuagkhaopong; Luis M. Bimbo; F. Philipp Seib, RSC Advances. 2024. https://doi.org/10.1039/D3RA07634B . 10.1039/D3RA07634B . RSC Advances

Microfibre-Functionalised Silk Hydrogels

Jirada Kaewchuchuen; Napaporn Roamcharern; Suttinee Phuagkhaopong; Luis M. Bimbo; F. Philipp Seib, Cells. 2023. https://doi.org/10.3390/cells13010010 . 10.3390/cells13010010 . Cells

Exploring the thermal behaviour of the solvated structures of nifedipine

Eleanor C. L. Jones; Kate E. Goldsmith; Martin R. Ward; Luis M. Bimbo; Iain D. H. Oswald, Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials. 2023. https://doi.org/10.1107/S2052520623001282 . 10.1107/S2052520623001282 . Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials

Pressure-induced superelastic behaviour of isonicotinamide

Eleanor C. L. Jones; Suse S. Bebiano; Martin R. Ward; Luis M. Bimbo; Iain D. H. Oswald, Chemical Communications. 11827 - 11830. 89. 57. 2021. https://doi.org/10.1039/D1CC04692F . 10.1039/D1CC04692F . published Chemical Communications

Crystallisation Behaviour of Pharmaceutical Compounds Confined within Mesoporous Silicon

Eleanor Jones; Luis M. Bimbo, Pharmaceutics. 2020. https://www.mdpi.com/1999-4923/12/3/214 . 10.3390/pharmaceutics12030214 . Pharmaceutics

Non-leaching, highly biocompatible nanocellulose surfaces that efficiently resist fouling by bacteria in an artificial dermis model

Ghada Hassan; Nina Forsman; Xing Wan; Leena Keurulainen; Luis M. Bimbo; Susanne Stehl; Frits van Charante; et al, ACS Applied Bio Materials. 4095 - 4108. 7. 3. 2020. https://pureportal.strath.ac.uk/en/publications/305bc888-5677-408f-bb25-68cd088bd746 . 10.1021/acsabm.0c00203 . ACS Applied Bio Materials

Dehydroabietylamine-based cellulose nanofibril films

Ghada Hassan; Nina Forsman; Xing Wan; Leena Keurulainen; Luis M. Bimbo; Leena-Sisko Johansson; Nina Sipari; et al, ACS Sustainable Chemistry and Engineering. 5002 - 5009. 5. 7. 2019. https://pureportal.strath.ac.uk/en/publications/983b57f2-a258-451a-bd92-fe7d73cd58c5 . 10.1021/acssuschemeng.8b05658 . ACS Sustainable Chemistry and Engineering

High-generation amphiphilic Janus-dendrimers as stabilizing agents for drug suspensions

Markus Selin; Sami Nummelin; Jill Deleu; Jarmo Ropponen; Tapani Viitala; Manu Lahtinen; Jari Koivisto; et al, Biomacromolecules. 3983 - 3993. 10. 19. 2018. https://pureportal.strath.ac.uk/en/publications/581f6744-864f-4362-acf0-de142640d2bf . 10.1021/acs.biomac.8b00931 . Biomacromolecules

Pulmonary administration of a dry powder formulation of the antifibrotic drug tilorone reduces silica-induced lung fibrosis in mice

Ville Vartiainen; Janne Raula; Luis M. Bimbo; Jenni Viinamäki; Janne T. Backman; Nurcin Ugur; Esko Kauppinen; et al, International Journal of Pharmaceutics. 121 - 128. 1. 544. 2018. https://pureportal.strath.ac.uk/en/publications/f028945c-644f-4072-ac7a-f8e643dc1d78 . 10.1016/j.ijpharm.2018.04.019 . International Journal of Pharmaceutics

Surface modification of acetaminophen particles by atomic layer deposition

Tommi O. Kääriäinen; Marianna Kemell; Marko Vehkamäki; Marja-Leena Kääriäinen; Alexandra Correia; Hélder A. Santos; Luis M. Bimbo; et al, International Journal of Pharmaceutics. 160 - 174. 1. 525. 2017. https://pureportal.strath.ac.uk/en/publications/8e3db7af-f7fa-4fdb-be42-ce2198de8440 . 10.1016/j.ijpharm.2017.04.031 . International Journal of Pharmaceutics

Modular synthesis of self-assembling Janus-dendrimers and facile preparation of drug-loaded dendrimersomes

Sami Nummelin; Markus Selin; Sacha Legrand; Jarmo Ropponen; Jani Seitsonen; Antti Nykänen; Jari Koivisto; et al, Nanoscale. 7189 - 7198. 21. 9. 2017. https://pureportal.strath.ac.uk/en/publications/4f093ac6-862f-4ae6-97c6-5ecce95a3929 . 10.1039/C6NR08102A . Nanoscale

Aerosolization, drug permeation and cellular interaction of dry powder pulmonary formulations of corticosteroids with hydroxypropyl-ß-cyclodextrin as a solubilizer

Ville Vartiainen; Luis M. Bimbo; Jouni Hirvonen; Esko I. Kauppinen; Janne Raula, Pharmaceutical Research. 25 - 35. 1. 34. 2017. https://pureportal.strath.ac.uk/en/publications/2da5ad0a-af99-4672-8a08-3d4384e603d3 . 10.1007/s11095-016-2035-9 . Pharmaceutical Research

Drug permeation and cellular interaction of amino acid-coated drug combination powders for pulmonary delivery

Vartiainen, Ville; Bimbo, Luis M.; Hirvonen, Jouni; Kauppinen, Esko I.; Raula, Janne, International Journal of Pharmaceutics. 89 - 97. 1-2. 504. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000375026900010&KeyUID=WOS:000375026900010 . 10.1016/j.ijpharm.2016.03.052 . International Journal of Pharmaceutics

Dendrimers and their supramolecular nanostructures for biomedical applications

Selin, Markus; Peltonen, Leena; Hirvonen, Jouni; Bimbo, Luis M., Journal of Drug Delivery Science and Technology. 10 - 20. 34. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000380594300003&KeyUID=WOS:000380594300003 . 10.1016/j.jddst.2016.02.008 . Journal of Drug Delivery Science and Technology

Aerosolization, Drug Permeation and Cellular Interaction of Leucine Coated Combination DPI Powders

Raula, Janne; Vartiainen, Ville; Kauppinen, Esko I.; Bimbo, Luis M.; Hirvonen, Jouni, Journal of Aerosol Medicine and Pulmonary Drug Delivery. A6 - A6. 3. 29. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000377378100018&KeyUID=WOS:000377378100018 . Journal of Aerosol Medicine and Pulmonary Drug Delivery

Self-Assembly of Amphiphilic Janus Dendrimers into Mechanically Robust Supramolecular Hydrogels for Sustained Drug Release.

Nummelin S; Liljeström V; Saarikoski E; Ropponen J; Nykänen A; Linko V; Seppälä J; et al, Chemistry -A European Journal. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000363331600026&KeyUID=WOS:000363331600026 . 10.1002/chem.201501812 . Chemistry -A European Journal

Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications.

Bimbo, Luís, Nanomedicine. 2014. http://europepmc.org/abstract/med/24787441 . 10.2217/nnm.13.223 . Nanomedicine

Nanostructured porous silicon in preclinical imaging: Moving from bench to bedside

Santos, Helder A.; Bimbo, Luis M.; Herranz, Barbara; Shahbazi, Mohammad-Ali; Hirvonen, Jouni; Salonen, Jarno, Journal of Materials Research. 152 - 164. 2. 28. 2013. 10.1557/jmr.2012.271 . Journal of Materials Research

Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles

Liu, Dongfei; Bimbo, Luis M.; Makila, Ermei; Villanova, Francesca; Kaasalainen, Martti; Herranz-Blanco, Barbara; Caramella, Carla M.; et al, Journal of Controlled Release. 268 - 278. 2. 170. 2013. http://www.sciencedirect.com/science/article/pii/S0168365913003283 . 10.1016/j.jconrel.2013.05.036 . Journal of Controlled Release

Inhibition of Influenza A Virus Infection in Vitro by Saliphenylhalamide-Loaded Porous Silicon Nanoparticles

Bimbo, Luis M.; Denisova, Oxana V.; Makila, Ermei; Kaasalainen, Martti; De Brabander, Jef K.; Hirvonen, Jouni; Salonen, Jarno; et al, Acs Nano. 6884 - 6893. 8. 7. 2013. 10.1021/nn402062f . Acs Nano

Toxicological profile of therapeutic nanodelivery systems.

Bimbo, Luís, Current Drug Metabolism. 2012. http://europepmc.org/abstract/med/22380014 . 10.2174/138920012802850047 . Current Drug Metabolism

A new cocrystal and salts of itraconazole: comparison of solid-state properties, stability and dissolution behavior.

Bimbo, Luís, International Journal of Pharmaceutics. 2012. http://europepmc.org/abstract/med/22750429 . 10.1016/j.ijpharm.2012.06.045 . International Journal of Pharmaceutics

Amine Modification of Thermally Carbonized Porous Silicon with Silane Coupling Chemistry

Makila, Ermei; Bimbo, Luis M.; Kaasalainen, Martti; Herranz, Barbara; Airaksinen, Anu J.; Heinonen, Markku; Kukk, Edwin; et al, Langmuir. 14045 - 14054. 39. 28. 2012. 10.1021/la303091k . Langmuir

Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

Sarparanta, Mirkka; Bimbo, Luis M.; Rytkonen, Jussi; Makila, Ermei; Laaksonen, Timo J.; Laaksonen, Paivi; Nyman, Markus; et al, Molecular Pharmaceutics. 654 - 663. 3. 9. 2012. 10.1021/mp200611d . Molecular Pharmaceutics

Cellular interactions of surface modified nanoporous silicon particles

Bimbo, Luis M.; Sarparanta, Mirkka; Makila, Ermei; Laaksonen, Timo; Laaksonen, Paivi; Salonen, Jarno; Linder, Markus B.; et al, Nanoscale. 3184 - 3192. 10. 4. 2012. 10.1039/c2nr30397c . Nanoscale

The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems

Sarparanta, Mirkka P.; Bimbo, Luis M.; Makila, Ermei M.; Salonen, Jarno J.; Laaksonen, Paivi H.; Helariutta, A. M. Kerttuli; Linder, Markus B.; et al, Biomaterials. 3353 - 3362. 11. 33. 2012. 10.1016/j.biomaterials.2012.01.029 . Biomaterials

Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment

Gomes-da-Silva, Ligia C.; Santos, Adriana O.; Bimbo, Luis M.; Moura, Vera; Ramalho, Jose S.; Pedroso de Lima, Maria C.; Simoes, Sergio; Moreira, Joao N., International Journal of Pharmaceutics. 9 - 19. 1-2. 434. 2012. 10.1016/j.ijpharm.2012.05.018 . International Journal of Pharmaceutics

Multifunctional porous silicon for therapeutic drug delivery and imaging.

Santos HA; Bimbo LM; Lehto VP; Airaksinen AJ; Salonen J; Hirvonen J, 2011. http://europepmc.org/abstract/med/21291407 . 10.2174/157016311796799053 .

Drug permeation across intestinal epithelial cells using porous silicon nanoparticles

Bimbo, Luis M.; Makila, Ermei; Laaksonen, Timo; Lehto, Vesa-Pekka; Salonen, Jarno; Hirvonen, Jouni; Santos, Helder A., Biomaterials. 2625 - 2633. 10. 32. 2011. 10.1016/j.biomaterials.2010.12.011 . Biomaterials

Functional hydrophobin-coating of thermally hydrocarbonized porous silicon microparticles

Bimbo, Luis M.; Makila, Ermei; Raula, Janne; Laaksonen, Timo; Laaksonen, Paivi; Strommer, Katharina; Kauppinen, Esko I.; et al, Biomaterials. 9089 - 9099. 34. 32. 2011. 10.1016/j.biomaterials.2011.08.011 . Biomaterials

Biocompatibility of Thermally Hydrocarbonized Porous Silicon Nanoparticles and their Biodistribution in Rats

BIMBO, LM; SARPARANTA, M; SANTOS, HA; AIRAKSINEN, AJ; MAKILA, E; LAAKSONEN, T; PELTONEN, L; et al, Acs Nano. 3023 - 3032. 6. 4. 2010. 10.1021/nn901657w . Acs Nano

Design of peptide-targeted liposomes containing nucleic acids

Santos, Adriana O.; Gomes da Silva, Ligia C.; Bimbo, Luis M.; Pedroso de Lima, Maria C.; Simoes, Sergio; Moreira, Joao N., Biochimica Et Biophysica Acta-Biomembranes. 433 - 441. 3. 1798. 2010. 10.1016/j.bbamem.2009.12.001 . Biochimica Et Biophysica Acta-Biomembranes

Tailoring in vitro cell responses of porous silicon micro- and nanoparticles

Hélder A. Santos; Luis M. Bimbo; Jarno Salonen; Vesa-Pekka Lehto; Jouni Hirvonen, CRS Newsletter. 10 - 11. 1. 27. 2010. https://pureportal.strath.ac.uk/en/publications/d0ef3f5f-90a4-487d-b5e0-2c6e30e19b9c . CRS Newsletter

5 33 de 33 Publicações

Todos os projectos

Informação da exclusiva responsabilidade do investigador 15-09-2024 , a partir da plataforma CIÊNCIAVITAE.

2018/09/01 - 2019/08/31

Composite hydrogels as scaffolds for cellular differentiation

RIG007771

Principal investigator

Strathclyde Institute of Pharmacy and Biomedical Sciences

Financiadores: Carnegie Trust for the Universities of Scotland

2014/01/01 - 2014/12/31

Functionalized Dendrimersomes for Drug Delivery

Not applicable

Principal investigator