Publicações
Informação sobre artigos em revista, actualizada a 16-02-2025, a partir da plataforma CIÊNCIAVITAE.
Brain-derived neurotrophic factor -induced regulation of RNA metabolism in neuronal development and synaptic plasticity
Rui O. Costa; Luís F. Martins; Emanuel Tahiri; Carlos B. Duarte, WIREs RNA. 2022. https://doi.org/10.1002/wrna.1713 . 10.1002/wrna.1713 . WIREs RNA
Isolation and Culture of Chick Ciliary Ganglion Neurons
Costa, Filipa J.; Dias, Marta S.; Costa, Rui O.; Pedro, Joana R.; Almeida, Ramiro D., Journal of Visualized Experiments. 162. 2020. http://dx.doi.org/10.3791/61431 . 10.3791/61431 . Journal of Visualized Experiments
Alterations in GABAA-Receptor Trafficking and Synaptic Dysfunction in Brain Disorders
Mele, Miranda; Costa, Rui O.; Duarte, Carlos B., Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/fncel.2019.00077 . 10.3389/fncel.2019.00077 . Frontiers in Cellular Neuroscience
Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons
Costa, Rui O.; Martins, Helena; Martins, Luís F.; Cwetsch, Andrzej W.; Mele, Miranda; Pedro, Joana R.; Tomé, Diogo; et al, Cell Reports. 864 - 876.e6. 4. 28. 2019. http://dx.doi.org/10.1016/j.celrep.2019.06.080 . 10.1016/j.celrep.2019.06.080 . Cell Reports
PROneurotrophins and CONSequences
Costa, R.O.; Perestrelo, T.; Almeida, R.D., Molecular Neurobiology. 1 - 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018273843&partnerID=MN8TOARS . 10.1007/s12035-017-0505-7 . Molecular Neurobiology
The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons
Graciano Leal; Diogo Comprido; Pasqualino de Luca; Eduardo Morais; Luís Rodrigues; Miranda Mele; Ana R. Santos; et al, eneuro. ENEURO.0268 - 17.2017. 6. 4. 2017. https://doi.org/10.1523/ENEURO.0268-17.2017 . 10.1523/ENEURO.0268-17.2017 . eneuro
Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF
Martins, L.F.; Costa, R.O.; Pedro, J.R.; Aguiar, P.; Serra, S.C.; Teixeira, F.G.; Sousa, N.; Salgado, A.J.; Almeida, R.D., Scientific Reports. 1. 7. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021292472&partnerID=MN8TOARS . 10.1038/s41598-017-03592-1 . Scientific Reports
Preparation of Primary Cultures of Embryonic Rat Hippocampal and Cerebrocortical Neurons
Salazar, Ivan; Mele, Miranda; Caldeira, Margarida; Costa, Rui; Correia, Bárbara; Frisari, Simone; Duarte, Carlos; Costa RO, BIO-PROTOCOL. 18. 7. 2017. http://dx.doi.org/10.21769/bioprotoc.2551 . 10.21769/bioprotoc.2551 . BIO-PROTOCOL
Visualizing K48 ubiquitination during presynaptic formation by ubiquitination-induced fluorescence complementation (UiFC)
Pinto, M.J.; Pedro, J.R.; Costa, R.O.; Almeida, R.D., Frontiers in Molecular Neuroscience. JUNE. 9. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978476683&partnerID=MN8TOARS . 10.3389/fnmol.2016.00043 . Frontiers in Molecular Neuroscience
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease
Costa, R.O.; Mota, S.I.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Inhibition of mitochondrial cytochrome c oxidase potentiates Aß-induced ER stress and cell death in cortical neurons
Costa, R.O.; Ferreiro, E.; Oliveira, C.R.; Pereira, C.M.F., Molecular and Cellular Neuroscience. 1 - 8. 52. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870349573&partnerID=MN8TOARS . 10.1016/j.mcn.2012.09.005 . Molecular and Cellular Neuroscience
Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers
Martins, I.; Gomes, S.; Costa, R.O.; Otvos, L.; Oliveira, C.R.; Resende, R.; Pereira, C.M.F., Neuroscience. 41 - 51. 241. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876430099&partnerID=MN8TOARS . 10.1016/j.neuroscience.2013.02.062 . Neuroscience
Mitochondrial- and endoplasmic reticulum-associated oxidative stress in alzheimers disease: From pathogenesis to biomarkers
Ferreiro, E.; Baldeiras, I.; Ferreira, I.L.; Costa, R.O.; Rego, A.C.; Pereira, C.F.; Oliveira, C.R., International Journal of Cell Biology. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863688106&partnerID=MN8TOARS . 10.1155/2012/735206 . International Journal of Cell Biology
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-ß oligomers
Costa, R.O.; Lacor, P.N.; Ferreira, I.L.; Resende, R.; Auberson, Y.P.; Klein, W.L.; Oliveira, C.R.; Rego, A.C.; Pereira, C.M.F., Aging Cell. 823 - 833. 5. 11. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866452758&partnerID=MN8TOARS . 10.1111/j.1474-9726.2012.00848.x . Aging Cell
Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions
Costa, R.O.; Ferreiro, E.; Martins, I.; Santana, I.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., Neurobiology of Aging. 4. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856951448&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2011.04.011 . Neurobiology of Aging
ER stress-mediated apoptotic pathway induced by aß peptide requires the presence of functional mitochondria
Costa, R.O.; Ferreiro, E.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., Journal of Alzheimer's Disease. 625 - 636. 2. 20. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954516455&partnerID=MN8TOARS . 10.3233/JAD-2010-091369 . Journal of Alzheimer's Disease
Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP 106-126
Ferreiro, E.; Costa, R.; Marques, S.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., Journal of Neurochemistry. 766 - 776. 3. 104. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38049162500&partnerID=MN8TOARS . 10.1111/j.1471-4159.2007.05048.x . Journal of Neurochemistry
An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity
Ferreiro, E.; Resende, R.; Costa, R.; Oliveira, C.R.; Pereira, C.M.F., Neurobiology of Disease. 669 - 678. 3. 23. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747195017&partnerID=MN8TOARS . 10.1016/j.nbd.2006.05.011 . Neurobiology of Disease
5 18 de 18 Publicações
Todos os projectos
Informação da exclusiva responsabilidade do investigador 16-02-2025 , a partir da plataforma CIÊNCIAVITAE.
2022 - 2023
The RNA-binding protein hnRNPH2: a novel player in epileptogenesis
n.a
Principal investigator
Center for Neurosciences and Cell Biology, University of Coimbra
2021/01/01 - 2025/12/31
Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2021/01/01 - 2025/12/31
Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2021/07/01 -
Uncovering the molecular machinery responsible for cargo sorting in neuronal polarization
PTDC/BIA-CEL/2286/2020
Researcher
Financiadores: Fundação para a Ciência e a Tecnologia
2019 -
Strategic Plan CNC.IBILI
UID/ NEU/04539/2019
Researcher
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2019/01/01 - 2019/12/31
CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2019/02/05 -
BaiTS - Biodegradable dendrimers for Targeted neuroprotective therapies in Stroke.
PTDC/CTM-NAN/3547/2014.
Researcher
2015 - 2018
Funding of RD Units Strategic Plan - 2013/2015 - OE
UID/NEU/04539/2013
Researcher
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2013 - 2014
Concurso para Financiamento de Projectos de IC&DT Estratégicos e de Interesse Público promovidos por Laboratórios Associados e Unidades de I&D - 2013 - COMPETE
PEst-C/SAU/LA0001/2013
Researcher
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2013/07 - 2014/12
Mechanism underlying ribosomal regulation in axonal development
grant.Provided by PTCRIS: 126236
Principal investigator
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2013/01/01 - 2019/02
Pos-Doc project: Mechanisms underlying ribosomal regulation in axonal development
SFRH/BPD/84593/2012
Post-doc Fellow
CNC.IBILI
Financiadores: Fundação para a Ciência e a Tecnologia
2011/01/01 - 2012/12/31
Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2011/01/01 - 2011/09/30
The role of mRNA translation in the formation of the neuromuscular junction.
PTDC/SAU-NEU/104100/2008
Research Technician Fellow
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2010/06/01 - 2013/06/30
Perfis dinâmicos do óxido nítrico no cérebro: regulação da respiração celular com implicações para a doença de Alzheimer e para o envelhecimento
PTDC/SAU-NEU/103538/2008
Universidade de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2010/06 - 2013/06
In vivo dynamics of nitric oxide in the brain: regulation of cellular respiration and implications for Alzheimer´s disease and aging
grant.Provided by PTCRIS: 103538
Researcher
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: Fundação para a Ciência e a Tecnologia
2008 - 2010
Contribution of N-methyl-D-aspartate receptor subunits to neuronal dysfunction in Alzheimer’s disease
PTDC/SAU-NEU/71675/2006
Researcher
Financiadores: Fundação para a Ciência e a Tecnologia
2008 - 2010
Early Diagnosis of Alzheimer’s Disease: evaluation of recent classification criteria and proposal of new diagnostic tools
PIC/IC/83206/2007
Researcher
Financiadores: Fundação para a Ciência e a Tecnologia
2006 - 2010
PhD project: Endoplasmic reticulum stress during amyloid ß peptide-induced cell death: role of mitochondria and glutamatergic N-methyl-D-aspartate receptors
SFRH/BD/28403/2006
PhD Student Fellow
CNC.IBILI
Financiadores: Fundação para a Ciência e a Tecnologia
2005 - 2006
Cross-talk between mitochondria and endoplasmic reticulum in Alzheimer’s disease. Studies with cybrids
n/a
Researcher
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: L’Oréal Portugal/UNESCO/FCT
2005 - 2006
Cross-talk between mitochondria and endoplasmic reticulum in Alzheimer’s disease. Studies with cybrids
n/a
Researcher
Center for Neurosciences and Cell Biology, University of Coimbra
Financiadores: L’Oréal Portugal/UNESCO/FCT
5 20 de 20 projetos
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