Neurociências e Doença

Sinalização Neuronal

Neurotrofinas

Aprendizagem & memória

Medo

Epilepsia

Isquémia cerebral

Doença de Alzheimer

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Carlos B. Duarte

Investigador(a)

Publicações

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Informação sobre artigos em revista, actualizada a 22-12-2024, a partir da plataforma CIÊNCIAVITAE.

Editorial: Long-lasting neurobehavioral effects of early-life events

Ventura, Rossella; Di Segni, Matteo; Santos, Mónica; Agustín-Pavón, Carmen; Torres-Pérez, Jose V., 2024. Frontiers in Neuroscience. 18. 2024. http://dx.doi.org/10.3389/fnins.2024.1509723 . 10.3389/fnins.2024.1509723 . Frontiers in Neuroscience

The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticity

Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz; Madeira, Maria Francisca; Tomé, Ângelo R.; Ferreira, Samira G.; et al, 2024. Molecular Psychiatry. 2024. http://dx.doi.org/10.1038/s41380-024-02412-z . 10.1038/s41380-024-02412-z . Molecular Psychiatry

The amygdala NT3-TrkC pathway underlies inter-individual differences in fear extinction and related synaptic plasticity

Masella, Gianluca; Silva, Francisca; Corti, Elisa; Azkona, Garikoitz; Madeira, Maria Francisca; Tomé, Ângelo R.; Ferreira, Samira G.; et al, 2024. Molecular Psychiatry. 2024. http://dx.doi.org/10.1038/s41380-024-02412-z . 10.1038/s41380-024-02412-z . in press Molecular Psychiatry

MiR-186-5p inhibition restores synaptic transmission and neuronal network activity in a model of chronic stress

Beatriz Rodrigues; Ricardo A. Leitão; Mónica Santos; Alexander Trofimov; Mariline Silva; Ângela S. Inácio; Mónica Abreu; et al, 2024. Molecular Psychiatry. 2024. https://doi.org/10.1038/s41380-024-02715-1 . 10.1038/s41380-024-02715-1 . Molecular Psychiatry

The role of post-translational modifications in synaptic AMPA receptor activity

Elisa Corti; Carlos B. Duarte, 2023. Biochemical Society Transactions. 2023. https://doi.org/10.1042/BST20220827 . 10.1042/BST20220827 . Biochemical Society Transactions

Biomarkers of hypoxic–ischemic encephalopathy: a systematic review

Inês Caramelo; Margarida Coelho; Miguel Rosado; Carla M. P. Cardoso; Alexandra Dinis; Carlos B. Duarte; Mário Grãos; Bruno Manadas, 2023. World Journal of Pediatrics. 505 - 548. 19. 2023. http://dx.doi.org/10.1007/s12519-023-00698-7 . 10.1007/s12519-023-00698-7 . World Journal of Pediatrics

Mitochondria as central hubs in synaptic modulation

Filipe V. Duarte; Daniele Ciampi; Carlos B. Duarte, 2023. Cellular and Molecular Life Sciences. 2023. https://doi.org/10.1007/s00018-023-04814-8 . 10.1007/s00018-023-04814-8 . Cellular and Molecular Life Sciences

TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear Memory

Francisca Silva; Gianluca Masella; Maria Francisca Madeira; Carlos B. Duarte; Mónica Santos, 2023. Molecular Neurobiology. 2023. https://doi.org/10.1007/s12035-023-03292-0 . 10.1007/s12035-023-03292-0 . Molecular Neurobiology

TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear Memory

Silva, Francisca; Masella, Gianluca; Madeira, Maria Francisca; Duarte, Carlos B.; Santos, Mónica, 2023. Molecular Neurobiology. 3507 - 3521. 6. 60. 2023. http://dx.doi.org/10.1007/s12035-023-03292-0 . 10.1007/s12035-023-03292-0 . Molecular Neurobiology

Molecular Mechanisms of Epilepsy: The Role of the Chloride Transporter KCC2

Giorgio Belperio; Claudia Corso; Carlos B. Duarte; Miranda Mele, 2022. Journal of Molecular Neuroscience. 2022. https://doi.org/10.1007/s12031-022-02041-7 . 10.1007/s12031-022-02041-7 . Journal of Molecular Neuroscience

Brain-derived neurotrophic factor -induced regulation of RNA metabolism in neuronal development and synaptic plasticity

Rui O. Costa; Luís F. Martins; Emanuel Tahiri; Carlos B. Duarte, 2022. WIREs RNA. 2022. https://doi.org/10.1002/wrna.1713 . 10.1002/wrna.1713 . WIREs RNA

Brain-derived neurotrophic factor -induced regulation of RNA metabolism in neuronal development and synaptic plasticity

Costa, Rui O.; Martins, Luís F.; Tahiri, Emanuel; Duarte, Carlos B., 2022. WIREs RNA. 2022. http://dx.doi.org/10.1002/wrna.1713 . 10.1002/wrna.1713 . published WIREs RNA

Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis

Salazar, Ivan L.; Lourenço, Ana S. T.; Manadas, Bruno; Baldeiras, Inês; Ferreira, Cláudia; Teixeira, Anabela Claro; Mendes, Vera M.; et al, 2022. Journal of Neuroinflammation. 1. 19. 2022. http://dx.doi.org/10.1186/s12974-022-02404-2 . 10.1186/s12974-022-02404-2 . Journal of Neuroinflammation

Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activity

Duarte, Carlos B., 2021. Scientific Reports. 1. 11. 2021. http://dx.doi.org/10.1038/s41598-021-90486-y . 10.1038/s41598-021-90486-y . Scientific Reports

MeCP2 haplodeficiency and early-life stress interaction on anxiety-like behavior in adolescent female mice

María Abellán-Álvaro; Oliver Stork; Carmen Agustín-Pavón; Mónica Santos, 2021. Journal of Neurodevelopmental Disorders. 2021. https://doi.org/10.1186/s11689-021-09409-7 . 10.1186/s11689-021-09409-7 . Journal of Neurodevelopmental Disorders

GRASP1 ubiquitination regulates AMPA receptor surface expression and synaptic activity in cultured hippocampal neurons

Duarte, Carlos B., 2021. The FASEB Journal. 8. 35. 2021. http://dx.doi.org/10.1096/fj.201903061rr . 10.1096/fj.201903061rr . The FASEB Journal

Isolation and Culture of Chick Ciliary Ganglion Neurons

Costa, Filipa J.; Dias, Marta S.; Costa, Rui O.; Pedro, Joana R.; Almeida, Ramiro D., 2020. Journal of Visualized Experiments. 162. 2020. http://dx.doi.org/10.3791/61431 . 10.3791/61431 . Journal of Visualized Experiments

Male-specific features are reduced in Mecp2-null mice: analyses of vasopressinergic innervation, pheromone production and social behaviour

Elena Martínez-Rodríguez; Ana Martín-Sánchez; Emre Kul; Aparajita Bose; Francisco José Martínez-Martínez; Oliver Stork; Fernando Martínez-García; et al, 2020. Brain Structure and Function. 2219 - 2238. 7. 225. 2020. https://doi.org/10.1007/s00429-020-02122-6 . 10.1007/s00429-020-02122-6 . Brain Structure and Function

Response of the cerebral vasculature to systemic carbon monoxide administration: Regional differences and sexual dimorphism

Oliveira, Sara R.; Castelhano, João; Sereno, José; Vieira, Helena L. A.; Duarte, Carlos B.; Castelo-Branco, Miguel, 2020. European Journal of Neuroscience. 2771 - 2780. 1. 52. 2020. http://dx.doi.org/10.1111/ejn.14725 . 10.1111/ejn.14725 . European Journal of Neuroscience

Polyamide 6.6 thin films with distinct ratios of the main chemical groups: Influence in the primary neuronal cell culture

Piedade, Ana P.; Veneza, Cátia; Duarte, Carlos B., 2019. Applied Surface Science. 30 - 37. 490. 2019. http://dx.doi.org/10.1016/j.apsusc.2019.06.066 . 10.1016/j.apsusc.2019.06.066 . Applied Surface Science

Alterations in GABAA-Receptor Trafficking and Synaptic Dysfunction in Brain Disorders

Mele, Miranda; Costa, Rui O.; Duarte, Carlos B., 2019. Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/fncel.2019.00077 . 10.3389/fncel.2019.00077 . Frontiers in Cellular Neuroscience

Alterations in GABAA-Receptor Trafficking and Synaptic Dysfunction in Brain Disorders

Mele, Miranda; Costa, Rui O.; Duarte, Carlos B., 2019. Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/fncel.2019.00077 . 10.3389/fncel.2019.00077 . Frontiers in Cellular Neuroscience

BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons

Pedro Afonso; Pasqualino De Luca; Rafael S. Carvalho; Luísa Cortes; Paulo Pinheiro; Barbara Oliveiros; Ramiro D. Almeida; Miranda Mele; Carlos B. Duarte, 2019. Science Signaling. eaav3577 - eaav3577. 586. 12. 2019. https://doi.org/10.1126/scisignal.aav3577 . 10.1126/scisignal.aav3577 . Science Signaling

Lack of MeCP2 leads to region-specific increase of doublecortin in the olfactory system

Martínez-Rodríguez, Elena; Martín-Sánchez, Ana; Coviello, Simona; Foiani, Cristina; Kul, Emre; Stork, Oliver; Martínez-García, Fernando; et al, 2019. Brain Structure and Function. 1647 - 1658. 4. 224. 2019. http://dx.doi.org/10.1007/s00429-019-01860-6 . 10.1007/s00429-019-01860-6 . published Brain Structure and Function

Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons

Costa, Rui O.; Martins, Helena; Martins, Luís F.; Cwetsch, Andrzej W.; Mele, Miranda; Pedro, Joana R.; Tomé, Diogo; et al, 2019. Cell Reports. 864 - 876.e6. 4. 28. 2019. http://dx.doi.org/10.1016/j.celrep.2019.06.080 . 10.1016/j.celrep.2019.06.080 . Cell Reports

BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo

Singer, W.; Manthey, M.; Panford-Walsh, R.; Matt, L.; Geisler, H.-S.; Passeri, E.; Baj, G.; et al, 2018. Frontiers in Molecular Neuroscience. 11. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054809235&partnerID=MN8TOARS . 10.3389/fnmol.2018.00325 . Frontiers in Molecular Neuroscience

P2X7 Receptors Mediate CO-Induced Alterations in Gene Expression in Cultured Cortical Astrocytes—Transcriptomic Study

Oliveira, S.R.; Figueiredo-Pereira, C.; Duarte, C.B.; Vieira, H.L.A., 2018. Molecular Neurobiology. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052053347&partnerID=MN8TOARS . 10.1007/s12035-018-1302-7 . Molecular Neurobiology

Downregulation of GABA<inf>A</inf>Receptor Recycling Mediated by HAP1 Contributes to Neuronal Death in In Vitro Brain Ischemia

Mele, M.; Aspromonte, M.C.; Duarte, C.B., 2017. Molecular Neurobiology. 45 - 57. 1. 54. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84953293603&partnerID=MN8TOARS . 10.1007/s12035-015-9661-9 . Molecular Neurobiology

Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF

Martins, L.F.; Costa, R.O.; Pedro, J.R.; Aguiar, P.; Serra, S.C.; Teixeira, F.G.; Sousa, N.; Salgado, A.J.; Almeida, R.D., 2017. Scientific Reports. 1. 7. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021292472&partnerID=MN8TOARS . 10.1038/s41598-017-03592-1 . Scientific Reports

Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.

Altmüller F; Pothula S; Annamneedi A; Nakhaei-Rad S; Montenegro-Venegas C; Pina-Fernández E; Marini C; et al, 2017. PLoS genetics. 2017. http://europepmc.org/abstract/med/28346493 . 10.1371/journal.pgen.1006684 . PLoS genetics

Erratum: Correction: Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy (PLoS genetics (2017) 13 3 (e1006684))

Altmüller, F.; Pothula, S.; Annamneedi, A.; Nakhaei-Rad, S.; Montenegro-Venegas, C.; Pina-Fernández, E.; Marini, C.; et al, 2017. PLoS genetics. e1006843 - e1006843. 6. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054771599&partnerID=MN8TOARS . 10.1371/journal.pgen.1006843 . PLoS genetics

Preparation of Primary Cultures of Embryonic Rat Hippocampal and Cerebrocortical Neurons

Salazar, Ivan; Mele, Miranda; Caldeira, Margarida; Costa, Rui; Correia, Bárbara; Frisari, Simone; Duarte, Carlos; Costa RO, 2017. BIO-PROTOCOL. 18. 7. 2017. http://dx.doi.org/10.21769/bioprotoc.2551 . 10.21769/bioprotoc.2551 . BIO-PROTOCOL

The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons

Graciano Leal; Diogo Comprido; Pasqualino de Luca; Eduardo Morais; Luís Rodrigues; Miranda Mele; Ana R. Santos; et al, 2017. eneuro. ENEURO.0268 - 17.2017. 6. 4. 2017. https://doi.org/10.1523/ENEURO.0268-17.2017 . 10.1523/ENEURO.0268-17.2017 . eneuro

Selective rescue of heightened anxiety but not gait ataxia in a premutation 90CGG mouse model of Fragile X-associated tremor/ataxia syndrome

Castro, Hoanna; Kul, Emre; Buijsen, Ronald A.M.; Severijnen, Lies-Anne W.F.M.; Willemsen, Rob; Hukema, Renate K.; Stork, Oliver; Santos, Mónica, 2017. Human Molecular Genetics. 2133 - 2145. 11. 26. 2017. http://dx.doi.org/10.1093/hmg/ddx108 . 10.1093/hmg/ddx108 . published Human Molecular Genetics

PROneurotrophins and CONSequences

Costa, R.O.; Perestrelo, T.; Almeida, R.D., 2017. Molecular Neurobiology. 1 - 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018273843&partnerID=MN8TOARS . 10.1007/s12035-017-0505-7 . Molecular Neurobiology

Infralimbic Neurotrophin-3 Infusion Rescues Fear Extinction Impairment in a Mouse Model of Pathological Fear

D'Amico, Davide; Gener, Thomas; de Lagrán, Maria Martínez; Sanchez-Vives, Maria V; Santos, Mónica; Dierssen, Mara, 2016. Neuropsychopharmacology. 462 - 472. 2. 42. 2016. http://dx.doi.org/10.1038/npp.2016.154 . 10.1038/npp.2016.154 . published Neuropsychopharmacology

Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury

Michele Curcio; Ivan L. Salazar; Miranda Mele; Lorella M.T. Canzoniero; Carlos B. Duarte, 2016. Progress in Neurobiology. 1 - 35. 143. 2016. http://dx.doi.org/10.1016/j.pneurobio.2016.06.001 . 10.1016/j.pneurobio.2016.06.001 . Progress in Neurobiology

Erratum to “Calpains and neuronal damage in the ischemic brain: The swiss knife in synaptic injury” (Progress in Neurobiology (2016) 147 (20) (S0301008216300090) (10.1016/j.pneurobio.2016.06.001))

Curcio, M.; Salazar, I.L.; Mele, M.; Canzoniero, L.M.T.; Duarte, C.B., 2016. Progress in Neurobiology. 147. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84997683943&partnerID=MN8TOARS . 10.1016/j.pneurobio.2016.08.004 . Progress in Neurobiology

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations

Mollereau, B.; Rzechorzek, N.M.; Roussel, B.D.; Sedru, M.; Van den Brink, D.M.; Bailly-Maitre, B.; Palladino, F.; et al, 2016. Brain Research. 603 - 616. 1648. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960193866&partnerID=MN8TOARS . 10.1016/j.brainres.2016.02.033 . Brain Research

Multiple domains in the C-terminus of NMDA receptor GluN2B subunit contribute to neuronal death following in vitro ischemia

Vieira, M.M.; Schmidt, J.; Ferreira, J.S.; She, K.; Oku, S.; Mele, M.; Santos, A.E.; et al, 2016. Neurobiology of Disease. 223 - 234. 89. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959360132&partnerID=MN8TOARS . 10.1016/j.nbd.2015.11.007 . Neurobiology of Disease

Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABA<inf>A</inf>Receptor Clustering and Contributes to Neuronal Death

Costa, J.T.; Mele, M.; Baptista, M.S.; Gomes, J.R.; Ruscher, K.; Nobre, R.J.; de Almeida, L.P.; Wieloch, T.; Duarte, C.B., 2016. Molecular Neurobiology. 3513 - 3527. 6. 53. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84931863889&partnerID=MN8TOARS . 10.1007/s12035-015-9283-2 . Molecular Neurobiology

Role of GABAA receptor trafficking in the plasticity of inhibitory synapses

Mele, M.; Leal, G.; Duarte, C.B., 2016. Journal of Neurochemistry. 997 - 1018. 6. 139. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84990020943&partnerID=MN8TOARS . 10.1111/jnc.13742 . Journal of Neurochemistry

Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) Motor Dysfunction Modeled in Mice

Foote, Molly; Arque, Gloria; Berman, Robert F.; Santos, Mónica, 2016. The Cerebellum. 611 - 622. 5. 15. 2016. http://dx.doi.org/10.1007/s12311-016-0797-6 . 10.1007/s12311-016-0797-6 . published The Cerebellum

7th ISN special neurochemistry conference ‘Synaptic function and dysfunction in brain diseases’

Duarte, C.B.; Carvalho, A.L., 2016. Journal of Neurochemistry. 918 - 920. 6. 139. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85002680853&partnerID=MN8TOARS . 10.1111/jnc.13839 . Journal of Neurochemistry

Visualizing K48 ubiquitination during presynaptic formation by ubiquitination-induced fluorescence complementation (UiFC)

Pinto, M.J.; Pedro, J.R.; Costa, R.O.; Almeida, R.D., 2016. Frontiers in Molecular Neuroscience. JUNE. 9. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84978476683&partnerID=MN8TOARS . 10.3389/fnmol.2016.00043 . Frontiers in Molecular Neuroscience

The role of proteases in hippocampal synaptic plasticity: Putting together small pieces of a complex puzzle

Salazar, I.L.; Caldeira, M.V.; Curcio, M.; Duarte, C.B., 2016. Neurochemical Research. 156 - 182. 1-2. 41. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946811163&partnerID=MN8TOARS . 10.1007/s11064-015-1752-5 . Neurochemical Research

Effect of carbon monoxide on gene expression in cerebrocortical astrocytes: Validation of reference genes for quantitative real-time PCR

Oliveira, S.R.; Vieira, H.L.A.; Duarte, C.B., 2015. Nitric Oxide - Biology and Chemistry. 80 - 89. 49. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938365745&partnerID=MN8TOARS . 10.1016/j.niox.2015.07.003 . Nitric Oxide - Biology and Chemistry

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

Costa, R.O.; Mota, S.I.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, 2015. Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Regulation of hippocampal synaptic plasticity by BDNF

Leal, G.; Afonso, P.M.; Salazar, I.L.; Duarte, C.B., 2015. Brain Research. 82 - 101. 1621. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941585404&partnerID=MN8TOARS . 10.1016/j.brainres.2014.10.019 . Brain Research

Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges

Bofill-De Ros, Xavier; Santos, Mónica; Vila-Casadesús, Maria; Villanueva, Eneko; Andreu, Nuria; Dierssen, Mara; Fillat, Cristina, 2015. BMC Genomics. 1. 16. 2015. http://dx.doi.org/10.1186/s12864-015-2160-6 . 10.1186/s12864-015-2160-6 . published BMC Genomics

Brain ischemia downregulates the neuroprotective GDNF-Ret signaling by a calpain-dependent mechanism in cultured hippocampal neurons

Curcio, M.; Salazar, I.L.; Inácio, A.R.; Duarte, E.P.; Canzoniero, L.M.T.; Duarte, C.B., 2015. Cell Death and Disease. 2. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84927597988&partnerID=MN8TOARS . 10.1038/cddis.2014.578 . Cell Death and Disease

Differential role of the proteasome in the early and late phases of BDNF-induced facilitation of LTP

Santos, Ana Rita; Mele, Miranda; Vaz, Sandra H.; Kellermayer, Blanka; Grimaldi, Maddalena; Oliveira, Mariana; Rombo, Diogo M.; et al, 2015. Journal of Neuroscience. 3319 - 3329. 8. 35. 2015. http://hdl.handle.net/10451/50238 . 10.1523/JNEUROSCI.4521-14.2015 . Journal of Neuroscience

From neural to genetic substrates of panic disorder: Insights from human and mouse studies

Santos, Mónica; D’Amico, Davide; Dierssen, Mara, 2015. European Journal of Pharmacology. 127 - 141. 759. 2015. http://dx.doi.org/10.1016/j.ejphar.2015.03.039 . 10.1016/j.ejphar.2015.03.039 . published European Journal of Pharmacology

Role of the ubiquitin-proteasome system in brain ischemia: Friend or foe?

Caldeira, M.V.; Salazar, I.L.; Curcio, M.; Canzoniero, L.M.T.; Duarte, C.B.; Baptista, M.S.; Maciel, P.; et al, 2014. Progress in Neurobiology. 50 - 69. 16. 112. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890805926&partnerID=MN8TOARS . 10.1016/j.pneurobio.2013.10.003 . Progress in Neurobiology

Identification of key genes involved in Down syndrome pathogenesis by gene therapy,Identificación de genes clave implicados en el síndrome de Down mediante terapia génica

Fillat, C.; Bofill-De Ros, X.; Santos, M.; Martín, E.D.; Andreu, N.; Villanueva, E.; D'Amico, D.; Dierssen, M.; Altafaj, X., 2014. SD Revista Medica Internacional sobre el Sindrome de Down. 21 - 28. 2. 18. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940262370&partnerID=MN8TOARS . 10.1016/S1138-2074(14)70049-1 . published SD Revista Medica Internacional sobre el Sindrome de Down

Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3

Vieira, M.; Fernandes, J.; Carreto, L.; Anuncibay-Soto, B.; Santos, M.; Han, J.; Fernández-López, A.; et al, 2014. Neurobiology of Disease. 26 - 36. 68. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899850247&partnerID=MN8TOARS . 10.1016/j.nbd.2014.04.002 . Neurobiology of Disease

Neuronal Activity Induces Synaptic Delivery of hnRNP A2/B1 by a BDNF-Dependent Mechanism in Cultured Hippocampal Neurons

Leal, Graciano; Afonso, Pedro M.; Duarte, Carlos B.; Melo, C.V.; Mele, M.; Curcio, M.; Comprido, D.; et al, 2014. PLoS ONE. 208 - 219. 10. 9. 2014. http://hdl.handle.net/10316/27646 . https://doi.org/10.1371/journal.pone.0108175 . PLoS ONE

BDNF-induced local protein synthesis and synaptic plasticity

Leal, Graciano; Comprido, Diogo; Duarte, Carlos B.; Leal, G.; Comprido, D.; Duarte, C.B., 2014. Neuropharmacology. 639 - 656. PART C. 76. 2014. http://hdl.handle.net/10316/25252 . https://doi.org/10.1016/j.neuropharm.2013.04.005 . Neuropharmacology

In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons

Fernandes, J.; Vieira, M.; Carreto, L.; Santos, M.A.S.; Duarte, C.B.; Carvalho, A.L.; Santos, A.E.; et al, 2014. PLoS ONE. 6. 9. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903512303&partnerID=MN8TOARS . 10.1371/journal.pone.0099958 . PLoS ONE

GABA<inf>A</inf>receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia

Mele, M.; Ribeiro, L.; Inácio, A.R.; Wieloch, T.; Duarte, C.B., 2014. Neurobiology of Disease. 220 - 232. 65. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896313006&partnerID=MN8TOARS . 10.1016/j.nbd.2014.01.019 . Neurobiology of Disease

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of machado-Joseph disease

Simões, A.T.; Gonçalves, N.; Nobre, R.J.; Duarte, C.B.; Pereira de Almeida, L., 2014. Human Molecular Genetics. 4932 - 4944. 18. 23. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906821927&partnerID=MN8TOARS . 10.1093/hmg/ddu209 . Human Molecular Genetics

Inhibition of mitochondrial cytochrome c oxidase potentiates Aß-induced ER stress and cell death in cortical neurons

Costa, R.O.; Ferreiro, E.; Oliveira, C.R.; Pereira, C.M.F., 2013. Molecular and Cellular Neuroscience. 1 - 8. 52. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870349573&partnerID=MN8TOARS . 10.1016/j.mcn.2012.09.005 . Molecular and Cellular Neuroscience

Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons

Caldeira, M.V.; Curcio, M.; Leal, G.; Salazar, I.L.; Mele, M.; Santos, A.R.A.; Melo, C.V.; et al, 2013. Biochimica et Biophysica Acta - Molecular Basis of Disease. 263 - 274. 1. 1832. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84868560715&partnerID=MN8TOARS . 10.1016/j.bbadis.2012.10.009 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers

Martins, I.; Gomes, S.; Costa, R.O.; Otvos, L.; Oliveira, C.R.; Resende, R.; Pereira, C.M.F., 2013. Neuroscience. 41 - 51. 241. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876430099&partnerID=MN8TOARS . 10.1016/j.neuroscience.2013.02.062 . Neuroscience

Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons

Melo, C.V.; Okumoto, S.; Gomes, J.R.; Baptista, M.S.; Bahr, B.A.; Frommer, W.B.; Duarte, C.B., 2013. Neuroscience. 66 - 86. 237. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874734906&partnerID=MN8TOARS . 10.1016/j.neuroscience.2013.01.054 . Neuroscience

Hippocampal Hyperexcitability Underlies Enhanced Fear Memories in TgNTRK3, a Panic Disorder Mouse Model

Santos, M.; D'Amico, D.; Spadoni, O.; Amador-Arjona, A.; Stork, O.; Dierssen, M., 2013. Journal of Neuroscience. 15259 - 15271. 38. 33. 2013. http://dx.doi.org/10.1523/jneurosci.2161-13.2013 . 10.1523/jneurosci.2161-13.2013 . published Journal of Neuroscience

Neuroprotection by GDNF in the ischemic brain

Duarte, E.P.; Curcio, M.; Canzoniero, L.M.; Duarte, C.B., 2012. Growth Factors. 242 - 257. 4. 30. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866129833&partnerID=MN8TOARS . 10.3109/08977194.2012.691478 . Growth Factors

Mitochondrial- and endoplasmic reticulum-associated oxidative stress in alzheimers disease: From pathogenesis to biomarkers

Ferreiro, E.; Baldeiras, I.; Ferreira, I.L.; Costa, R.O.; Rego, A.C.; Pereira, C.F.; Oliveira, C.R., 2012. International Journal of Cell Biology. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863688106&partnerID=MN8TOARS . 10.1155/2012/735206 . International Journal of Cell Biology

Amyloid ß-induced ER stress is enhanced under mitochondrial dysfunction conditions

Costa, R.O.; Ferreiro, E.; Martins, I.; Santana, I.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., 2012. Neurobiology of Aging. 4. 33. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856951448&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2011.04.011 . Neurobiology of Aging

Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-ß oligomers

Costa, R.O.; Lacor, P.N.; Ferreira, I.L.; Resende, R.; Auberson, Y.P.; Klein, W.L.; Oliveira, C.R.; Rego, A.C.; Pereira, C.M.F., 2012. Aging Cell. 823 - 833. 5. 11. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866452758&partnerID=MN8TOARS . 10.1111/j.1474-9726.2012.00848.x . Aging Cell

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease

Simões, A.T.; Gonçalves, N.; Koeppen, A.; Déglon, N.; Kügler, S.; Duarte, C.B.; Pereira De Almeida, L., 2012. Brain. 2428 - 2439. 8. 135. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864658791&partnerID=MN8TOARS . 10.1093/brain/aws177 . Brain

Contactin-associated protein 1 (Caspr1) regulates the traffic and synaptic content of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors

Santos, S.D.; Iuliano, O.; Ribeiro, L.; Veran, J.; Ferreira, J.S.; Rio, P.; Mulle, C.; Duarte, C.B.; Carvalho, A.L., 2012. Journal of Biological Chemistry. 6868 - 6877. 9. 287. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857468361&partnerID=MN8TOARS . 10.1074/jbc.M111.322909 . Journal of Biological Chemistry

Excitotoxicity downregulates TrkB.FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons

Gomes, J.R.; Costa, J.T.; Melo, C.V.; Felizzi, F.; Monteiro, P.; Pinto, M.J.; Inácio, A.R.; et al, 2012. Journal of Neuroscience. 4610 - 4622. 13. 32. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859013000&partnerID=MN8TOARS . 10.1523/JNEUROSCI.0374-12.2012 . Journal of Neuroscience

Proteomics-Based technologies in the discovery of biomarkers for multiple sclerosis in the cerebrospinal fluid

Lourenço, A.S.T.; Baldeiras, I.; Grãos, M.; Duarte, C.B., 2011. Current Molecular Medicine. 326 - 349. 4. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958096423&partnerID=MN8TOARS . Current Molecular Medicine

Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites

Gomes, J.R.; Lobo, A.C.; Melo, C.V.; Inácio, A.R.; Takano, J.; Iwata, N.; Saido, T.C.; et al, 2011. Journal of Neuroscience. 4622 - 4635. 12. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953008096&partnerID=MN8TOARS . 10.1523/JNEUROSCI.3541-10.2011 . Journal of Neuroscience

Rett syndrome with and without detected MECP2 mutations: An attempt to redefine phenotypes

Temudo, Teresa; Santos, Mónica; Ramos, Elisabete; Dias, Karin; Vieira, José Pedro; Moreira, Ana; Calado, Eulália; et al, 2011. Brain and Development. 69 - 76. 1. 33. 2011. http://dx.doi.org/10.1016/j.braindev.2010.01.004 . 10.1016/j.braindev.2010.01.004 . published Brain and Development

Signal transduction profile of chemical sensitisers in dendritic cells: An endpoint to be included in a cell-based in vitro alternative approach to hazard identification?

Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.; Cruz, M.T., 2011. Toxicology and Applied Pharmacology. 87 - 95. 2. 250. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650559757&partnerID=MN8TOARS . 10.1016/j.taap.2010.10.003 . Toxicology and Applied Pharmacology

Cleavage of the vesicular glutamate transporters under excitotoxic conditions

Lobo, A.C.; Gomes, J.R.; Catarino, T.; Mele, M.; Fernandez, P.; Inácio, A.R.; Bahr, B.A.; et al, 2011. Neurobiology of Disease. 292 - 303. 3. 44. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053269066&partnerID=MN8TOARS . 10.1016/j.nbd.2011.07.010 . Neurobiology of Disease

Proteomic analysis of an interactome for long-form AMPA receptor subunits

Santos, S.D.; Manadas, B.; Duarte, C.B.; Carvalho, A.L., 2010. Journal of Proteome Research. 1670 - 1682. 4. 9. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950666645&partnerID=MN8TOARS . 10.1021/pr900766r . Journal of Proteome Research

ER stress-mediated apoptotic pathway induced by aß peptide requires the presence of functional mitochondria

Costa, R.O.; Ferreiro, E.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., 2010. Journal of Alzheimer's Disease. 625 - 636. 2. 20. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954516455&partnerID=MN8TOARS . 10.3233/JAD-2010-091369 . Journal of Alzheimer's Disease

Effect of lipopolysaccharide, skin sensitizers and irritants on thioredoxin-1 expression in dendritic cells: Relevance of different signalling pathways

Francisco, V.; Neves, B.M.; Cruz, M.T.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2010. Archives of Dermatological Research. 271 - 282. 4. 302. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952180893&partnerID=MN8TOARS . 10.1007/s00403-009-0993-z . Archives of Dermatological Research

Regulation of local translation at the synapse by BDNF

Santos, A.R.; Comprido, D.; Duarte, C.B., 2010. Progress in Neurobiology. 505 - 516. 4. 92. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956664066&partnerID=MN8TOARS . 10.1016/j.pneurobio.2010.08.004 . Progress in Neurobiology

Excitotoxicity through Ca<sup>2+</sup>-permeable AMPA receptors requires Ca<sup>2+</sup>-dependent JNK activation

Vieira, M.; Fernandes, J.; Burgeiro, A.; Thomas, G.M.; Huganir, R.L.; Duarte, C.B.; Carvalho, A.L.; Santos, A.E., 2010. Neurobiology of Disease. 645 - 655. 3. 40. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957795389&partnerID=MN8TOARS . 10.1016/j.nbd.2010.08.008 . Neurobiology of Disease

Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons

Baptista, M.S.; Melo, C.V.; Armelão, M.; Herrmann, D.; Pimentel, D.O.; Leal, G.; Caldeira, M.V.; et al, 2010. PLoS ONE. 4. 5. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956333111&partnerID=MN8TOARS . 10.1371/journal.pone.0010139 . PLoS ONE

Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome

Santos, M.; Summavielle, T.; Teixeira-Castro, A.; Silva-Fernandes, A.; Duarte-Silva, S.; Marques, F.; Martins, L.; et al, 2010. Neuroscience. 453 - 467. 2. 170. 2010. http://dx.doi.org/10.1016/j.neuroscience.2010.07.010 . 10.1016/j.neuroscience.2010.07.010 . published Neuroscience

Juice of Bryophyllum pinnatum (Lam.) inhibits oxytocin-induced increase of the intracellular calcium concentration in human myometrial cells

Simões-Wüst, A.P.; Grãos, M.; Duarte, C.B.; Brenneisen, R.; Hamburger, M.; Mennet, M.; Ramos, M.H.; et al, 2010. Phytomedicine. 980 - 986. 12. 17. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956619629&partnerID=MN8TOARS . 10.1016/j.phymed.2010.03.005 . Phytomedicine

Mutations in the MECP2 Gene Are Not a Major Cause of Rett Syndrome-Like or Related Neurodevelopmental Phenotype in Male Patients

Santos, Mónica; Temudo, Teresa; Kay, Teresa; Carrilho, Inês; Medeira, Ana; Cabral, Helena; Gomes, Roseli; et al, 2009. Journal of Child Neurology. 49 - 55. 1. 24. 2009. http://dx.doi.org/10.1177/0883073808321043 . 10.1177/0883073808321043 . published Journal of Child Neurology

Differential roles of PI3-Kinase, MAPKs and NF-¿B on the manipulation of dendritic cell T<inf>h</inf>1/T<inf>h</inf>2 cytokine/chemokine polarizing profile

Neves, B.M.; Cruz, M.T.; Francisco, V.; Garcia-Rodriguez, C.; Silvestre, R.; Cordeiro-da-Silva, A.; Dinis, A.M.; et al, 2009. Molecular Immunology. 2481 - 2492. 13. 46. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650397827&partnerID=MN8TOARS . 10.1016/j.molimm.2009.05.021 . Molecular Immunology

BDNF-induced changes in the expression of the translation machinery in hippocampal neurons: Protein levels and dendritic mRNA

Manadas, B.; Santos, A.R.; Szabadfi, K.; Gomes, J.R.; Garbis, S.D.; Fountoulakis, M.; Duarte, C.B., 2009. Journal of Proteome Research. 4536 - 4552. 10. 8. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349976976&partnerID=MN8TOARS . 10.1021/pr900366x . Journal of Proteome Research

Regulation of AMPA receptors and synaptic plasticity

Santos, S.D.; Carvalho, A.L.; Caldeira, M.V.; Duarte, C.B., 2009. Neuroscience. 105 - 125. 1. 158. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149467917&partnerID=MN8TOARS . 10.1016/j.neuroscience.2008.02.037 . Neuroscience

Role of the brain-derived neurotrophic factor at glutamatergic synapses

Carvalho, A.L.; Caldeira, M.V.; Santos, S.D.; Duarte, C.B., 2008. British Journal of Pharmacology. SUPPL. 1. 153. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-40349114504&partnerID=MN8TOARS . 10.1038/sj.bjp.0707509 . British Journal of Pharmacology

Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP 106-126

Ferreiro, E.; Costa, R.; Marques, S.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., 2008. Journal of Neurochemistry. 766 - 776. 3. 104. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38049162500&partnerID=MN8TOARS . 10.1111/j.1471-4159.2007.05048.x . Journal of Neurochemistry

Analysis of Highly Conserved Regions of the 3’UTR of MECP2 Gene in Patients with Clinical Diagnosis of Rett Syndrome and Other Disorders Associated with Mental Retardation

Santos, Mónica; Yan, Jin; Temudo, Teresa; Oliveira, Guiomar; Vieira, José Pedro; Fen, Jinong; Sommer, Steve; Maciel, Patrícia, 2008. Disease Markers. 319 - 324. 6. 24. 2008. http://dx.doi.org/10.1155/2008/738401 . 10.1155/2008/738401 . published Disease Markers

In vitro behavior and surface morphology of modified 316L stainless steel stents

Nunes, J.; Piedade, A.P.; Duarte, C.B.; Vieira, M.T., 2008. Microscopy and Microanalysis. 35 - 36. SUPPL. 3. 14. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-53349102289&partnerID=MN8TOARS . 10.1017/S1431927608089307 . Microscopy and Microanalysis

The C677T Polymorphism inMTHFRIs Not Associated with Migraine in Portugal

Ferro, Anabela; Castro, Maria-José; Lemos, Carolina; Santos, Mónica; Sousa, Alda; Pereira-Monteiro, José; Sequeiros, Jorge; Maciel, Patrícia, 2008. Disease Markers. 107 - 113. 2. 25. 2008. http://dx.doi.org/10.1155/2008/178679 . 10.1155/2008/178679 . published Disease Markers

Characterization of alternatively spliced isoforms of AMPA receptor subunits encoding truncated receptors

Gomes, André R.; Ferreira, Joana S.; Paternain, Ana V.; Lerma, Juan; Duarte, Carlos B.; Carvalho, Ana Luísa; Gomes, A.R.; et al, 2008. Molecular and Cellular Neuroscience. 323 - 334. 2. 37. 2008. http://hdl.handle.net/10316/5314 . https://doi.org/10.1016/j.mcn.2007.10.008 . Molecular and Cellular Neuroscience

T-1237C polymorphism of TLR9 gene is not associated with multiple sclerosis in the Portuguese population

Carvalho, A.; Santos, M.; Maciel, P.; Rodrigues, F., 2008. Multiple Sclerosis Journal. 550 - 552. 4. 14. 2008. http://dx.doi.org/10.1177/1352458507084594 . 10.1177/1352458507084594 . published Multiple Sclerosis Journal

Differential modulation of CXCR4 and CD40 protein levels by skin sensitizers and irritants in the FSDC cell line

Neves, Bruno Miguel; Cruz, Maria Teresa; Francisco, Vera; Gonçalo, Margarida; Figueiredo, Américo; Duarte, Carlos B.; Lopes, Maria Celeste; et al, 2008. Toxicology Letters. 74 - 82. 1. 177. 2008. http://hdl.handle.net/10316/5843 . https://doi.org/10.1016/j.toxlet.2007.12.006 . Toxicology Letters

An explanation for another familial case of Rett syndrome: maternal germline mosaicism

Venâncio, Margarida; Santos, Mónica; Pereira, Susana Aires; Maciel, Patrícia; Saraiva, Jorge M, 2007. European Journal of Human Genetics. 902 - 904. 8. 15. 2007. http://dx.doi.org/10.1038/sj.ejhg.5201835 . 10.1038/sj.ejhg.5201835 . published European Journal of Human Genetics

MECP2 coding sequence and 3'UTR variation in 172 unrelated autistic patients

Coutinho, Ana M.; Oliveira, Guiomar; Katz, Cécile; Feng, Jinong; Yan, Jin; Yang, Chunmei; Marques, Carla; et al, 2007. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 475 - 483. 4. 144B. 2007. http://dx.doi.org/10.1002/ajmg.b.30490 . 10.1002/ajmg.b.30490 . published American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Stereotypies in Rett syndrome: Analysis of 83 patients with and without detected MECP2 mutations

Temudo, T.; Oliveira, P.; Santos, M.; Dias, K.; Vieira, J.; Moreira, A.; Calado, E.; et al, 2007. Neurology. 1183 - 1187. 15. 68. 2007. http://dx.doi.org/10.1212/01.wnl.0000259086.34769.78 . 10.1212/01.wnl.0000259086.34769.78 . published Neurology

Evidence for abnormal early development in a mouse model of Rett syndrome.

Santos M; Silva-Fernandes A; Oliveira P; Sousa N; Maciel P; Santos, M.; Silva-Fernandes, A.; et al, 2007. Genes, Brain and Behavior. 277 - 286. 3. 6. 2007. http://europepmc.org/abstract/med/16848781 . 10.1111/j.1601-183X.2006.00258.x . published Genes, Brain and Behavior

Effects of mood stabilizers on the inhibition of adenylate cyclase via dopamine D<inf>2</inf>-like receptors

Montezinho, L.P.; Mørk, A.; Duarte, C.B.; Penschuck, S.; Geraldes, C.F.G.C.; Castro, M.M.C.A., 2007. Bipolar Disorders. 290 - 297. 3. 9. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34147106555&partnerID=MN8TOARS . 10.1111/j.1399-5618.2007.00354.x . Bipolar Disorders

Effect of skin sensitizers on inducible nitric oxide synthase expression and nitric oxide production in skin dendritic cells: Role of different immunosuppressive drugs

Cruz, M.T.; Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2007. Immunopharmacology and Immunotoxicology. 225 - 241. 2. 29. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548553284&partnerID=MN8TOARS . 10.1080/08923970701512304 . Immunopharmacology and Immunotoxicology

PKC Anchoring to GluR4 AMPA Receptor Subunit Modulates PKC-Driven Receptor Phosphorylation and Surface Expression

Gomes, André R.; Correia, Susana S.; Esteban, José A.; Duarte, Carlos B.; Carvalho, Ana Luísa; Cunha, Paulo; Nuriya, Mutsuo; et al, 2007. Journal of Neurochemistry. 673 - 682. 3. 90. 2007. http://hdl.handle.net/10316/8317 . https://doi.org/10.1111/j.1600-0854.2006.00521.x . Journal of Neurochemistry

Corrigendum to "Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans" [J. Neuroimmunol. 179 (2006) 108-116] (DOI:10.1016/j.jneuroim.2006.06.003)

Ban, M.; Booth, D.; Heard, R.; Stewart, G.; Goris, A.; Vandenbroeck, K.; Dubois, B.; et al, 2007. Journal of Neuroimmunology. 175 - 176. 1-2. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548554091&partnerID=MN8TOARS . 10.1016/j.jneuroim.2007.08.003 . Journal of Neuroimmunology

Erratum: Brain-derived neurotrophic factor regulates the expression and synaptic delivery of a-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons (Journal of Biological Chemistry (2007) 282, (12619-12628))

Caldeira, M.V.; Melo, C.V.; Pereira, D.B.; Carvalho, R.; Correia, S.S.; Backos, D.S.; Carvalho, A.L.; Esteban, J.A.; Duarte, C.B., 2007. Journal of Biological Chemistry. 37. 282. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34848900818&partnerID=MN8TOARS . Journal of Biological Chemistry

Trkb receptors modulation of glutamate release is limited to a subset of nerve terminals in the adult rat hippocampus

Pereira, Daniela B.; Rebola, Nelson; Rodrigues, Ricardo J.; Cunha, Rodrigo A.; Carvalho, Arsélio P.; Duarte, Carlos B.; Pereira, D.B.; et al, 2006. Journal of Neuroscience Research. 832 - 844. 5. 83. 2006. http://hdl.handle.net/10316/8320 . https://doi.org/10.1002/jnr.20784 . Journal of Neuroscience Research

Chromatin remodeling and neuronal function: exciting links

Santos, M.; Coelho, P. A.; Maciel, P., 2006. Genes, Brain and Behavior. 80 - 91. 5. 2006. http://dx.doi.org/10.1111/j.1601-183x.2006.00227.x . 10.1111/j.1601-183x.2006.00227.x . published Genes, Brain and Behavior

The interaction between dopamine D<inf>2</inf>-like and beta-adrenergic receptors in the prefrontal cortex is altered by mood-stabilizing agents

Montezinho, L.P.; Castro, M.M.C.A.; Duarte, C.B.; Penschuck, S.; Geraldes, C.F.G.C.; Mørk, A.; Montezinho, Liliana P.; et al, 2006. Journal of Neurochemistry. 1336 - 1348. 5. 96. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645101243&partnerID=MN8TOARS . 10.1111/j.1471-4159.2005.03654.x . Journal of Neurochemistry

Excitotoxicity mediated by Ca<sup>2+</sup>-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor

Santos, A.E.; Duarte, C.B.; Iizuka, M.; Barsoumian, E.L.; Ham, J.; Lopes, M.C.; Carvalho, A.P.; Carvalho, A.L., 2006. Cell Death and Differentiation. 652 - 660. 4. 13. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644935364&partnerID=MN8TOARS . 10.1038/sj.cdd.4401785 . Cell Death and Differentiation

Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans

The GAMES Collaborative Group, 2006. Journal of Neuroimmunology. 108 - 116. 1-2. 179. 2006. http://dx.doi.org/10.1016/j.jneuroim.2006.06.003 . 10.1016/j.jneuroim.2006.06.003 . published Journal of Neuroimmunology

Sample sonication after trichloroacetic acid precipitation increases protein recovery from cultured hippocampal neurons, and improves resolution and reproducibility in two-dimensional gel electrophoresis

Manadas, Bruno J.; Vougas, Konstantinos; Fountoulakis, Michael; Duarte, Carlos B.; Manadas, B.J.; Vougas, K.; Fountoulakis, M.; Duarte, C.B., 2006. Electrophoresis. 1825 - 1831. 9. 27. 2006. http://hdl.handle.net/10316/8319 . https://doi.org/10.1002/elps.200500757 . Electrophoresis

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity

Ferreiro, E.; Resende, R.; Costa, R.; Oliveira, C.R.; Pereira, C.M.F., 2006. Neurobiology of Disease. 669 - 678. 3. 23. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747195017&partnerID=MN8TOARS . 10.1016/j.nbd.2006.05.011 . Neurobiology of Disease

APOE epsilon variation in multiple sclerosis susceptibility and disease severity: Some answers

Burwick, R. M.; Ramsay, P. P.; Haines, J. L.; Hauser, S. L.; Oksenberg, J. R.; Pericak-Vance, M. A.; Schmidt, S.; et al, 2006. Neurology. 1373 - 1383. 9. 66. 2006. http://dx.doi.org/10.1212/01.wnl.0000210531.19498.3f . 10.1212/01.wnl.0000210531.19498.3f . published Neurology

Detection of heterozygous deletions and duplications in the MECP2 gene in Rett syndrome by Robust Dosage PCR (RD-PCR)

Shi, Jinxiu; Shibayama, Akane; Liu, Qiang; Nguyen, Vu Q.; Feng, Jinong; Santos, Monica; Temudo, Teresa; Maciel, Patricia; Sommer, Steve S., 2005. Human Mutation. 505 - 505. 5. 25. 2005. http://dx.doi.org/10.1002/humu.9338 . 10.1002/humu.9338 . published Human Mutation

Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line

Cruz, M.T.; Gonçalo, M.; Paiva, A.; Morgado, J.M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2005. Archives of Dermatological Research. 43 - 47. 1. 297. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-25644435637&partnerID=MN8TOARS . 10.1007/s00403-005-0574-8 . Archives of Dermatological Research

DNFB activates MAPKs and upregulates CD40 in skin-derived dendritic cells

Matos, T.J.; Duarte, C.B.; Gonçalo, M.; Lopes, M.C.; Matos, Teresa J.; Duarte, Carlos B.; Gonçalo, Margarida; et al, 2005. Journal of Dermatological Science. 113 - 123. 2. 39. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23044493875&partnerID=MN8TOARS . 10.1016/j.jdermsci.2005.03.011 . published Journal of Dermatological Science

Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways

Almeida, R.D.; Manadas, B.J.; Melo, C.V.; Gomes, J.R.; Mendes, C.S.; Grãos, M.M.; Carvalho, R.F.; Carvalho, A.P.; Duarte, C.B., 2005. Cell Death and Differentiation. 1329 - 1343. 10. 12. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144508812&partnerID=MN8TOARS . 10.1038/sj.cdd.4401662 . Cell Death and Differentiation

Release of IL-1ß via IL-1ß-converting enzyme in a skin dendritic cell line exposed to 2,4-dinitrofluorobenzene

Matos, T.J.; Jaleco, S.P.; Gonçalo, M.; Duarte, C.B.; Lopes, M.C., 2005. Mediators of Inflammation. 131 - 138. 3. 2005. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-25644454243&partnerID=MN8TOARS . 10.1155/MI.2005.131 . Mediators of Inflammation

Role of oxidative stress in ERK and p38 MAPK activation induced by the chemical sensitizer DNFB in a fetal skin dendritic cell line

Matos, T.J.; Duarte, C.B.; Gonçalo, M.; Lopes, M.C.; Matos, Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Lopes, Maria Celeste, 2005. Immunology and Cell Biology. 607 - 614. 6. 83. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-30544454184&partnerID=MN8TOARS . 10.1111/j.1440-1711.2005.01378.x . published Immunology and Cell Biology

Intracellular signaling mechanisms in photodynamic therapy

Almeida, R.D.; Manadas, B.J.; Carvalho, A.P.; Duarte, C.B.; Almeida, Ramiro D.; Manadas, Bruno J.; Carvalho, Arsélio P.; Duarte, Carlos B., 2004. Biochimica et Biophysica Acta - Reviews on Cancer. 59 - 86. 2. 1704. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-4444265338&partnerID=MN8TOARS . 10.1016/j.bbcan.2004.05.003 . Biochimica et Biophysica Acta - Reviews on Cancer

Genotypes at the APOE and SCA2 loci do not predict the course of multiple sclerosis in patients of Portuguese origin

Santos, Mónica; do Carmo Costa, Maria; Rio, Maria Edite; Sá, Maria José; Monteiro, Marta; Valença, Angela; Sá, Alfredo; et al, 2004. Multiple Sclerosis Journal. 153 - 157. 2. 10. 2004. http://dx.doi.org/10.1191/1352458504ms998oa . 10.1191/1352458504ms998oa . published Multiple Sclerosis Journal

Calpains are activated by photodynamic therapy but do not contribute to apoptotic tumor cell death

Almeida, Ramiro D.; Gomes, Edgar R.; Carvalho, Arsélio P.; Duarte, Carlos B.; Almeida, R.D.; Gomes, E.R.; Carvalho, A.P.; Duarte, C.B., 2004. Cancer Letters. 183 - 189. 2. 216. 2004. http://hdl.handle.net/10316/5373 . https://doi.org/10.1016/j.canlet.2004.07.006 . Cancer Letters

The sensitizers nickel sulfate and 2,4-dinitrofluorobenzene induce the expression of CD40 and IL-12 receptor in a fetal skin dendritic cell line, whereas 2,4-dichloronitrobenzene has no effect.

Vital, A. L.; Gonçalo, Margarida; Cruz, Maria Teresa; Figueiredo, Américo; Duarte, Carlos B.; Lopes, Maria Celeste, 2004. Bioscience Reports . 191 - 202. 24. 2004. published Bioscience Reports

Intracellular lithium and cyclic AMP levels are mutually regulated in neuronal cells

Montezinho, L.P.; Duarte, C.B.; Fonseca, C.P.; Glinka, Y.; Layden, B.; Mota De Freitas, D.; Geraldes, C.F.G.C.; Castro, M.M.C.A., 2004. Journal of Neurochemistry. 920 - 930. 4. 90. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-4143076854&partnerID=MN8TOARS . 10.1111/j.1471-4159.2004.02551.x . Journal of Neurochemistry

The contact sensitizer Nickel sulphate activates the transcription factor NF-kB and AP-1 and induces the expression of nitric oxide in a skin dendritic cell line

Cruz, Maria Teresa; Gonçalo, Margarida; Américo Figueiredo; Carvalho A. P.; Duarte, Carlos B.; Lopes, Maria Celeste, 2004. Experimental Dermatol . 18 - 26. 13. 2004. published Experimental Dermatol

A whole genome screen for association with multiple sclerosis in Portuguese patients

Santos, M.; Pinto-Basto, J.; Rio, M.E.; Sá, M.J.; Valença, A.; Sá, A.; Dinis, J.; et al, 2003. Journal of Neuroimmunology. 112 - 115. 1-2. 143. 2003. http://dx.doi.org/10.1016/j.jneuroim.2003.08.023 . 10.1016/j.jneuroim.2003.08.023 . published Journal of Neuroimmunology

Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-¿B activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

Vital, A.L.; Gonçalo, M.; Cruz, M.T.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.; Cruz, Maria Teresa; et al, 2003. Mediators of Inflammation. 71 - 78. 2. 12. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038466135&partnerID=MN8TOARS . 10.1080/0962935031000097673 . Mediators of Inflammation

Dexamethasone prevents GM-CSF induced NF-kB activation, iNOS expression and NO production in a skin dendritic cell line

Vital, A. L.; Gonçalo, Margarida; Cruz, Maria Teresa; Duarte, Carlos B.; Figueiredo, Américo; Carvalho A. P.; Lopes, Maria Celeste, 2003. Mediators Inflammation . 71 - 78. 12. 2003. published Mediators Inflammation

Dexamethasone-induced and estradiol-induced CREB activation and annexin 1 expression in CCRF-CEM lymphoblastic cells: Evidence for the involvement of cAMP and p38 MAPK

Castro-Caldas, M.; Mendes, A.F.; Duarte, C.B.; Lopes, M.C.F., 2003. Mediators of Inflammation. 329 - 337. 6. 12. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0742286852&partnerID=MN8TOARS . 10.1080/09629350310001633351 . Mediators of Inflammation

Protein kinase C¿ associates directly with the GluR4 a-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit: Effect on receptor phosphorylation

Santos Correia, S.; Bandeira Duarte, C.; Faro, C.J.; Vieira Pires, E.; Carvalho, A.L., 2003. Journal of Biological Chemistry. 6307 - 6313. 8. 278. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037458663&partnerID=MN8TOARS . 10.1074/jbc.M205587200 . Journal of Biological Chemistry

The sensitizer 2,4 dinitrofluorbenzene induces cell death in a skin dendritic cell line by activating caspase 3

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Figueiredo, Américo; Carvalho A. P.; Lopes, Maria Celeste, 2003. International Journal of Toxicology . 43 - 48. 22. 2003. published International Journal of Toxicology

Dexamethasone prevents interleukin-1ß-induced nuclear factor-¿B activation by upregulating I¿B-a synthesis, in lymphoblastic cells

Castro-Caldas, M.; Mendes, A.F.; Carvalho, A.P.; Duarte, C.B.; Lopes, M.C., 2003. Mediators of Inflammation. 37 - 46. 1. 12. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037657851&partnerID=MN8TOARS . 10.1080/0962935031000096953 . Mediators of Inflammation

Regulation of AMPA Receptor Activity, Synaptic Targeting and Recycling: Role in Synaptic Plasticity

Gomes, André R.; Correia, Susana S.; Carvalho, Ana Luísa; Duarte, Carlos B.; Gomes, A.R.; Correia, S.S.; Carvalho, A.L.; Duarte, C.B., 2003. Neurochemical Research. 1459 - 1473. 10. 28. 2003. http://hdl.handle.net/10316/7904 . https://doi.org/10.1023/A:1025610122776 . Neurochemical Research

Genistein inhibits Ca2+ influx and glutamate release from hippocampal synaptosomes: putative non-specific effects

Pereira, Daniela B.; Carvalho, Arsélio P.; Duarte, Carlos B.; Pereira, D.B.; Carvalho, A.P.; Duarte, C.B., 2003. Neurochemistry International. 179 - 188. 2. 42. 2003. http://hdl.handle.net/10316/5409 . https://doi.org/10.1016/S0197-0186(02)00071-2 . Neurochemistry International

Analysis of the presynaptic signaling mechanisms underlying the inhibition of LTP in Rat Dentate Gyrus by the Tyrosine Kinase Ihibitor, Genistein

Pereira, D.B.; Duarte, C.B.; Pereira, Daniela B.; Duarte, Carlos B., 2003. Hippocampus. 978 - 979. 8. 13. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346505474&partnerID=MN8TOARS . 10.1002/hipo.10148 . Hippocampus

Differential activation of nuclear factor Kappa B subunits in a dendritic cell line in response to the strong sensitizer 2,4-dinitrofluorbenzene.

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Figueiredo, Américo; Carvalho A. P.; Lopes, Maria Celeste; Cruz MT; et al, 2002. Arch Dermatol Research. 419 - 425. 294. 294. 2002. http://europepmc.org/abstract/med/12522580 . published Arch Dermatol Research

Nitric oxide modulates tumor cell death induced by photodynamic therapy through a cGMP-dependent mechanism

Gomes, E.R.; Almeida, R.D.; Carvalho, A.P.; Duarte, C.B., 2002. Photochemistry and Photobiology. 423 - 430. 4. 76. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036782294&partnerID=MN8TOARS . 10.1562/0031-8655(2002)076&lt;0423:NOMTCD&gt;2.0.CO;2 . Photochemistry and Photobiology

Phosphorylation of GluR4 AMPA-type glutamate receptor subunit by protein kinase C in cultured retina amacrine neurons

Carvalho, A.L.; Correia, S.; Faro, C.J.; Duarte, C.B.; Carvalho, A.P.; Pires, E.M.V., 2002. European Journal of Neuroscience. 465 - 474. 3. 15. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036456320&partnerID=MN8TOARS . 10.1046/j.0953-816x.2001.01881.x . European Journal of Neuroscience

Non-specific effects of the MEK inhibitors PD098,059 and U0126 on glutamate release from hippocampal synaptosomes

Pereira, D.B.; Carvalho, A.P.; Duarte, C.B., 2002. Neuropharmacology. 9 - 19. 1. 42. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036142796&partnerID=MN8TOARS . 10.1016/S0028-3908(01)00162-9 . Neuropharmacology

Dexamethasone induces the secretion of annexin I in immature lymphoblastic cells by a calcium-dependent mechanism

Castro-Caldas, M.; Duarte, C.B.; Carvalho, A.P.; Fernandes Lopes, M.C., 2002. Molecular and Cellular Biochemistry. 31 - 38. 1-2. 237. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036686832&partnerID=MN8TOARS . 10.1023/A:1016502120139 . Molecular and Cellular Biochemistry

LPS induction of IkB-¿ degradation and iNOS expression in a skin dendritic cell line is prevented by the Janus Kinase 2 inhibitor, tyrphostin B42

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Carvalho A. P.; Lopes, Maria Celeste; Cruz, M.T.; Duarte, C.B.; et al, 2001. Nitric Oxide: Biology and Chemistry . 53 - 61. 5. 5. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035708551&partnerID=MN8TOARS . 10.1006/niox.2000.0320 . published Nitric Oxide: Biology and Chemistry

17beta-estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line

Castro-Caldas, Margarida; Duarte, Carlos B.; Carvalho, Arsélio P.; Lopes, M. Celeste, 2001. 2001. http://hdl.handle.net/10316/12762 . https://doi.org/10.1080/09629350120093713 .

17ß-Estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line

Castro-Caldas, M.; Duarte, C.B.; Carvalho, A.P.; Celeste Lopes, M., 2001. Mediators of Inflammation. 245 - 251. 5. 10. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034747177&partnerID=MN8TOARS . 10.1080/09629350120093713 . Mediators of Inflammation

Adenosine A1 receptors inhibit Ca2+ channels coupled to the release of ACh, but not of GABA, in cultured retina cells

Santos, Paulo F.; Caramelo, Olga L.; Carvalho, Arsélio P.; Duarte, Carlos B., 2000. 2000. http://hdl.handle.net/10316/5455 . https://doi.org/10.1016/S0006-8993(99)02155-1 .

Regulation of AMPA Receptors by Phosphorylation

Carvalho, Ana Luísa; Duarte, Carlos B.; Carvalho, Arsélio P.; Carvalho, A.L.; Duarte, C.B.; Carvalho, A.P., 2000. Neurochemical Research. 1245 - 1255. 9-10. 25. 2000. http://hdl.handle.net/10316/7910 . https://doi.org/10.1023/A:1007644128886 . Neurochemical Research

Adenosine A<inf>1</inf> receptors inhibit Ca<sup>2+</sup> channels coupled to the release of ACh, but not of GABA, in cultured retina cells

Santos, P.F.; Caramelo, O.L.; Carvalho, A.P.; Duarte, C.B., 2000. Brain Research. 10 - 15. 1. 852. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033621543&partnerID=MN8TOARS . 10.1016/S0006-8993(99)02155-1 . Brain Research

Photosensitization of lymphoblastoid cells with phthalocyanines at different saturating incubation times

Gomes, E.R.; Cruz, T.; Lopes, C.F.; Carvalho, A.P.; Duarte, C.B., 1999. Cell Biology and Toxicology. 249 - 260. 4. 15. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033367925&partnerID=MN8TOARS . 10.1023/A:1007615813184 . Cell Biology and Toxicology

Involvement of JAK2 and MAPK on type II nitric oxide synthase expression in skin-derived dendritic cells

Cruz, M.T.; Duarte, C.B.; Gonçalo, M.; Carvalho, A.P.; Lopes, M.G., 1999. American Journal of Physiology - Cell Physiology. 6 46-6. 277. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033373205&partnerID=MN8TOARS . American Journal of Physiology - Cell Physiology

Corelease of two functionally opposite neurotransmitters by retinal amacrine cells: Experimental evidence and functional significance

Duarte, C.B.; Santos, P.F.; Carvalho, A.P.; Duarte, Carlos B.; Santos, Paulo F.; Carvalho, Arsélio P., 1999. Journal of Neuroscience Research. 475 - 479. 4. 58. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033571086&partnerID=MN8TOARS . 10.1002/(SICI)1097-4547(19991115)58:4&lt;475::AID-JNR1&gt;3.0.CO;2-O . Journal of Neuroscience Research

Characterization of ATP release from cultures enriched in cholinergic amacrine-like neurons

Santos, P.F.; Caramelo, O.L.; Carvalho, A.P.; Duarte, C.B.; Santos, Paulo F.; Caramelo, Olga L.; Carvalho, Arsélio P.; Duarte, Carlos B., 1999. Journal of Neurobiology. 340 - 348. 3. 41. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033571302&partnerID=MN8TOARS . 10.1002/(SICI)1097-4695(19991115)41:3&lt;340::AID-NEU3&gt;3.0.CO;2-8 . published Journal of Neurobiology

Nitric oxide differentially affects the exocytotic and the carrier-mediated release of [<sup>3</sup>H]¿-aminobutyric acid in rat hippocampal synaptosomes

Sequeira, S.M.; Duarte, C.B.; Carvalho, A.P.; Carvalho, C.M., 1998. Molecular Brain Research. 337 - 340. 2. 55. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032052170&partnerID=MN8TOARS . 10.1016/S0169-328X(98)00021-7 . Molecular Brain Research

Glutamate in Life and Death of Retinal Amacrine Cells*

Duarte, Carlos B.; Ferreira, Ildete L.; Santos, Paulo F.; Carvalho, Ana L.; Agostinho, Paula M.; Carvalho, Arsélio P.; Duarte, C.B.; et al, 1998. General Pharmacology. 289 - 295. 3. 30. 1998. http://hdl.handle.net/10316/5469 . https://doi.org/10.1016/S0306-3623(97)00360-1 . General Pharmacology

[3H]Acetylcholine release from rat amacrine-like neurons is inhibited by adenosine A1 receptor activation

Santos, Paulo F.; Caramelo, Olga L.; Carvalho, Arsélio P.; Duarte, Carlos B., 1998. NeuroReport. 3692 - 3698. 16. 9. 1998. 10.1097/00001756-199811160-00023 . published NeuroReport

Differential acetylcholine and GABA release from cultured chick retina cells

Santos, P.F.; Carvalho, A.L.; Carvalho, A.P.; Duarte, C.B., 1998. European Journal of Neuroscience. 2723 - 2730. 8. 10. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031927252&partnerID=MN8TOARS . 10.1046/j.1460-9568.1998.00281.x . European Journal of Neuroscience

Calcium influx through AMPA receptors and through calcium channels is regulated by protein kinase C in cultured retina amacrine-like cells

Carvalho, A.L.; Duarte, C.B.; Faro, C.J.; Carvalho, A.P.; Pires, E.V., 1998. Journal of Neurochemistry. 2112 - 2119. 5. 70. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031980737&partnerID=MN8TOARS . Journal of Neurochemistry

Culture medium components modulate retina cell damage induced by glutamate, kainate or 'chemical ischemia'

Ferreira, I.L.; Duarte, C.B.; Neves, A.R.; Carvalho, A.P., 1998. Neurochemistry International. 387 - 396. 4. 32. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032053747&partnerID=MN8TOARS . 10.1016/S0197-0186(97)00099-5 . Neurochemistry International

Modulation of [<sup>3</sup>H]acetylcholine release from cultured amacrine-like neurons by adenosine A<inf>1</inf>receptors

Santos, P.F.; Santos, M.S.; Carvalho, A.P.; Duarte, C.B., 1998. Journal of Neurochemistry. 1086 - 1094. 3. 71. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031595164&partnerID=MN8TOARS . Journal of Neurochemistry

Kainate-induced retina amacrine-like cell damage is mediated by AMPA receptors

Ferreira, I.L.; Duarte, C.B.; Carvalho, A.P., 1998. NeuroReport. 3471 - 3475. 15. 9. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032569601&partnerID=MN8TOARS . 10.1097/00001756-199810260-00025 . NeuroReport

[<sup>3</sup>H]Acetylcholine release from rat amacrine-like neurons is inhibited by adenosine A<inf>1</inf>receptor activation

Santos, P.F.; Caramelo, O.L.; Carvalho, A.P.; Duarte, C.B., 1998. NeuroReport. 3693 - 3698. 16. 9. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032538658&partnerID=MN8TOARS . NeuroReport

'Chemical ischemia' in cultured retina cells: The role of excitatory amino acid receptors and of energy levels on cell death

Ferreira, I.L.; Duarte, C.B.; Carvalho, A.P., 1997. Brain Research. 157 - 166. 1-2. 768. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030756369&partnerID=MN8TOARS . 10.1016/S0006-8993(97)00634-3 . Brain Research

Oxidative stress affects the selective ion permeability of voltage-sensitive Ca<sup>2+</sup> channels in cultured retinal cells

Agostinho, P.; Duarte, C.B.; Carvalho, A.P.; Oliveira, C.R., 1997. Neuroscience Research. 323 - 334. 4. 27. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030951140&partnerID=MN8TOARS . 10.1016/S0168-0102(96)01165-0 . Neuroscience Research

Impairment of excitatory amino acid transporter activity by oxidative stress conditions in retinal cells: Effect of antioxidants

Agostinho, P.; Duarte, C.B.; Oliveira, C.R.; Agostinho, Paulo; Duarte, Carlos B.; Oliveira, Catarina R., 1997. FASEB Journal. 154 - 163. 2. 11. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031027249&partnerID=MN8TOARS . FASEB Journal

Ca2+ influx through glutamate receptorassociated channels in retina cells correlates with neuronal cell death

Ferreira, I.L.; Duarte, C.B.; Carvalho, A.P., 1996. Biochemical Society Transactions. 4. 24. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749180144&partnerID=MN8TOARS . Biochemical Society Transactions

Voltage-sensitive Ca<sup>2+</sup> channels in rat striatal synaptosomes: Role on the [Ca<sup>2+</sup>]<inf>i</inf> responses to membrane depolarization

Duarte, C.B.; Cristóvão, A.J.; Carvalho, A.P.; Carvalho, C.M., 1996. Neurochemistry International. 67 - 75. 1. 28. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029656264&partnerID=MN8TOARS . 10.1016/0197-0186(95)00056-E . Neurochemistry International

Glutamate release evoked by glutamate receptor agonists in cultured chick retina cells: Modulation by arachidonic acid

Duarte, C.B.; Santos, P.F.; Sánchez-Prieto, J.; Carvalho, A.P., 1996. Journal of Neuroscience Research. 363 - 373. 4. 44. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029923724&partnerID=MN8TOARS . 10.1002/(SICI)1097-4547(19960515)44:4&lt;363::AID-JNR8&gt;3.0.CO;2-A . Journal of Neuroscience Research

Activity of ionotropic glutamate receptors in retinal cells: Effect of ascorbate/Fe<sup>2+</sup>-induced oxidative stress

Agostinho, P.; Duarte, C.B.; Oliveira, C.R., 1996. Journal of Neurochemistry. 1153 - 1163. 3. 67. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029801193&partnerID=MN8TOARS . Journal of Neurochemistry

Ca<sup>2+</sup>influx through glutamate receptor-associated channels in retina cells correlates with neuronal cell death

Ferreira, I.L.; Duarte, C.B.; Carvalho, A.P., 1996. European Journal of Pharmacology. 153 - 162. 1-3. 302. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029658975&partnerID=MN8TOARS . 10.1016/0014-2999(96)00044-1 . European Journal of Pharmacology

Release of glutamate by chick retina cells in culture: Role of Ca<sup>2+</sup> and arachidonic acid

Carvalho, A.; Santos, P.; Ferreira, I.; Duarte, C., 1996. Investigative Ophthalmology and Visual Science. 3. 37. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750149373&partnerID=MN8TOARS . Investigative Ophthalmology and Visual Science

Intracellular free Na<sup>+</sup>concentration increases in cultured retinal cells under oxidative stress conditions

Agostinho, P.; Duarte, C.B.; Oliveira, C.R., 1996. Neuroscience Research. 343 - 351. 4. 25. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029770633&partnerID=MN8TOARS . 10.1016/S0168-0102(96)01058-9 . Neuroscience Research

On-line detection of glutamate release from cultured chick retinospheroids

Duarte, C.B.; Santos, P.F.; Sánchez-Prieto, J.; Carvalho, A.P., 1996. Vision Research. 1867 - 1872. 13. 36. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030008951&partnerID=MN8TOARS . 10.1016/0042-6989(95)00309-6 . Vision Research

Glutamate receptor agonists evoked Ca<sup>2+</sup>-dependent and Ca<sup>2+</sup>-independent release of [<sup>3</sup>H]D-aspartate from cultured chick retina cells

Santos, P.F.; Duarte, C.B.; Carvalho, A.P., 1996. Neurochemical Research. 361 - 368. 3. 21. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030006280&partnerID=MN8TOARS . 10.1007/BF02531653 . Neurochemical Research

[Ca<sup>2+</sup>]<inf>i</inf>regulation by glutamate receptor agonists in cultured chick retina cells

Duarte, C.B.; Santos, P.F.; Carvalho, A.P., 1996. Vision Research. 1091 - 1102. 8. 36. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029670184&partnerID=MN8TOARS . 10.1016/0042-6989(95)00208-1 . Vision Research

Glutamate Receptor Modulation of [<sup>3</sup>H]GABA Release and Intracellular Calcium in Chick Retina Cells

CARVALHO, A.P.; FERREIRA, I.L.; CARVALHO, A.L.; DUARTE, C.B., 1995. Annals of the New York Academy of Sciences. 439 - 456. 757. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029100401&partnerID=MN8TOARS . 10.1111/j.1749-6632.1995.tb17504.x . accepted Annals of the New York Academy of Sciences

Characterization of Voltage-Sensitive Ca<sup>2+</sup>Channels Activated by Presynaptic Glutamate Receptor Stimulation in Hippocampus

CARVALHO, C.M.; MALVA, J.O.; DUARTE, C.B.; CARVALHO, A.P., 1995. Annals of the New York Academy of Sciences. 457 - 459. 757. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029129986&partnerID=MN8TOARS . 10.1111/j.1749-6632.1995.tb17505.x . accepted Annals of the New York Academy of Sciences

Involvement of class A calcium channels in the KCl induced Ca<sup>2+</sup> influx in hippocampal synaptosomes

Malva, J.O.; Ambrósio, A.F.; Carvalho, A.P.; Duarte, C.B.; Carvalho, C.M., 1995. Brain Research. 242 - 245. 1-2. 696. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028860747&partnerID=MN8TOARS . 10.1016/0006-8993(95)00816-9 . Brain Research

Relation of [Ca<sup>2+</sup>]<inf>i</inf>to dopamine release in striatal synaptosomes: role of Ca<sup>2+</sup>channels

Carvalho, C.M.; Ferreira, I.L.; Duarte, C.B.; Malva, J.O.; Tretter, L.; Adam-Vizi, V.; Carvalho, A.P., 1995. Brain Research. 234 - 244. 2. 669. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028839020&partnerID=MN8TOARS . 10.1016/0006-8993(94)01252-D . Brain Research

Influence of oxidative stress on membrane potential and on K<sup>+</sup>channels in neuronal cells

Agostinho, P.; Duarte, C.B.; Oliveira, C.R., 1995. Bioelectrochemistry and Bioenergetics. 297 - 305. 2. 38. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0343743141&partnerID=MN8TOARS . 10.1016/0302-4598(95)01850-E . Bioelectrochemistry and Bioenergetics

Modulation of N-methyl-d-aspartate receptor activity by oxidative stress conditions in chick retinal cells

Agostinho, P.; Duarte, C.B.; Carvalho, A.P.; Oliveira, C.R., 1995. Neuroscience Letters. 193 - 196. 3. 198. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028973020&partnerID=MN8TOARS . 10.1016/0304-3940(95)11996-A . Neuroscience Letters

Release of [<sup>3</sup>H]GABA evoked by glutamate receptor agonists in cultured chick retina cells: effect of Ca<sup>2+</sup>

Ferreira, I.L.; Duarte, C.B.; Santos, P.F.; Carvalho, C.M.; Carvalho, A.P., 1994. Brain Research. 252 - 256. 1-2. 664. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028172872&partnerID=MN8TOARS . 10.1016/0006-8993(94)91981-X . Brain Research

Domoic acid induced release of [<sup>3</sup>H]GABA in cultured chick retina cells

Alfonso, M.; Duran, R.; Duarte, C.B.; Ferreira, I.L.; Carvalho, A.P., 1994. Neurochemistry International. 267 - 274. 3. 24. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028218977&partnerID=MN8TOARS . 10.1016/0197-0186(94)90084-1 . Neurochemistry International

Effect of oxidative stress on the release of [<sup>3</sup>H]GABA in cultured chick retina cells

Agostinho, P.; Duarte, C.B.; Carvalho, A.P.; Oliveira, C.R., 1994. Brain Research. 213 - 221. 1-2. 655. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027931845&partnerID=MN8TOARS . 10.1016/0006-8993(94)91616-0 . Brain Research

Reactive Oxygen Species on GABA Release: GABA RELEASE

OLIVEIRA, C.R.; AGOSTINHO, P.; CASEIRO, P.; DUARTE, C.B.; CARVALHO, A.P., 1994. Annals of the New York Academy of Sciences. 130 - 140. 738. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028609848&partnerID=MN8TOARS . 10.1111/j.1749-6632.1994.tb21798.x . accepted Annals of the New York Academy of Sciences

Relation of exocytotic release of ¿-aminobutyric acid to Ca<sup>2+</sup> entry through Ca<sup>2+</sup> channels or by reversal of the Na<sup>+</sup>/Ca<sup>2+</sup> exchanger in synaptosomes

Duarte, C.B.; Ferreira, I.L.; Carvalho, A.P.; Carvalho, C.M., 1993. Pflügers Archiv European Journal of Physiology. 314 - 323. 3-4. 423. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027263283&partnerID=MN8TOARS . 10.1007/BF00374411 . Pflügers Archiv European Journal of Physiology

A Toxin Fraction (FTX) from the Funnel-Web Spider Poison Inhibits Dihydropyridine-Insensitive Ca<sup>2+</sup>Channels Coupled to Catecholamine Release in Bovine Adrenal Chromaffin Cells

Duarte, C.B.; Rosario, L.M.; Sena, C.M.; Carvalho, A.P.; Duarte, Carlos B.; Rosário, Luís M.; Sena, Cristina M.; Carvalho, Arsélio P., 1993. Journal of Neurochemistry. 908 - 913. 3. 60. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027477686&partnerID=MN8TOARS . 10.1111/j.1471-4159.1993.tb03236.x . Journal of Neurochemistry

Glutamate increases the [Ca<sup>2+</sup>]<inf>i</inf> but stimulates Ca<sup>2+</sup>-independent release of [<sup>3</sup>H]GABA in cultured chick retina cells

Duarte, C.B.; Ferreira, I.L.; Santos, P.F.; Oliveira, C.R.; Carvalho, A.P., 1993. Brain Research. 130 - 138. 1. 611. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027335488&partnerID=MN8TOARS . 10.1016/0006-8993(93)91784-P . Brain Research

Neomycin blocks dihydropyridine-insensitive Ca<sup>2+</sup>influx in bovine adrenal chromaffin cells

Duarte, C.B.; Tome, A.R.; Forsberg, E.; Carvalho, C.A.M.; Carvalho, A.P.; Santos, R.M.; Rosario, L.M., 1993. European Journal of Pharmacology: Molecular Pharmacology. 259 - 267. 3. 244. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027536487&partnerID=MN8TOARS . 10.1016/0922-4106(93)90151-X . European Journal of Pharmacology: Molecular Pharmacology

Ca<sup>2+</sup>-dependent release of [<sup>3</sup>H]GABA in cultured chick retina cells

Duarte, C.B.; Ferreira, I.L.; Santos, P.F.; Oliveira, C.R.; Carvalho, A.P., 1992. Brain Research. 27 - 32. 1. 591. 1992. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026668073&partnerID=MN8TOARS . 10.1016/0006-8993(92)90974-E . Brain Research

Regulation of carrier-mediated and exocytotic release of [<sup>3</sup>H]GABA in rat brain synaptosomes

Carvalho, C.M.; Bandeira-Duarte, C.; Ferreira, I.L.; Carvalho, A.P., 1991. Neurochemical Research. 763 - 772. 7. 16. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025820698&partnerID=MN8TOARS . 10.1007/BF00965685 . Neurochemical Research

Synaptosomal [Ca<sup>2+</sup>]<inf>i</inf> as influenced by Na<sup>+</sup> Ca<sup>2+</sup> exchange and K<sup>+</sup> depolarization

Duarte, C.B.; Carvalho, C.A.M.; Ferreira, I.L.; Carvalho, A.P., 1991. Cell Calcium. 623 - 633. 9. 12. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025917963&partnerID=MN8TOARS . 10.1016/0143-4160(91)90059-N . Cell Calcium

Sodium-calcium exchange in nerve terminals: Influence on internal Ca2+ and neurosecretion

Carvalho, A.P.; Bandeira-Duarte, C.; Ferreira, I.L.; Coutinho, O.P.; Carvalho, C.M., 1991. Annals of the New York Academy of Sciences. 300 - 311. 639. 1991. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026377475&partnerID=MN8TOARS . Annals of the New York Academy of Sciences

Influence of isolation media on synaptosomal properties: Intracellular pH, pCa, and Ca<sup>2+</sup>uptake

Bandeira-Duarte, C.; Carvalho, C.A.M.; Cragoe Jr., E.J.; Carvalho, A.P., 1990. Neurochemical Research. 313 - 320. 3. 15. 1990. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025240818&partnerID=MN8TOARS . 10.1007/BF00968678 . Neurochemical Research

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