Publicações
Informação sobre artigos em revista, actualizada a 20-04-2025, a partir da plataforma CIÊNCIAVITAE.
Does sperm need to sleep? An overview of the impact of sleep disturbances on male (in)fertility.
Carvalhas-Almeida , Catarina; Maria Inês Cristo; Cavadas, Claudia; Ramalho-Santos, João; Álvaro, Ana Rita ; Sandra Amaral, Sleep Medicine Reviews . 2024. submitted Sleep Medicine Reviews
The mystery of fatal familial insomnia.
Duarte, Raquel; Carvalhas-Almeida , Catarina; Santos, Bárbara; Gaspar, Laetitia S; Varela Amaral, Sara; Joao Cardoso; Rita Félix; et al, Frontiers for Young Minds. 2024. submitted Frontiers for Young Minds
Treatment with Continuous Positive Airway Pressure Alters Transcriptomic and Epigenomic Signatures of Obstructive Sleep Apnea
Gaspar, Laetitia S.; Smith, David F.; Pyakurel, Santoshi; Santos, Bárbara; Carvalhas-Almeida, Catarina; Ferreira, Mafalda; Moita, Joaquim; et al, European Respiratory Journal . 2024. submitted European Respiratory Journal
Differential expression of microRNAs in Obstructive Sleep Apnea: a systematic review and pathway analysis.
Gaspar, Laetitia S; CAPITÃO, ANA; Santos, Bárbara; Mendes, Alexandrina Ferreira ; Cavadas, Claudia; Moreira, Irina S; Álvaro, Ana Rita , Journal of Advanced Research. 2024. submitted Journal of Advanced Research
Modeling hypothalamic pathophysiology in vitro for metabolic, circadian, and sleep disorders
Leal, Helena; Carvalhas-Almeida, Catarina; Álvaro, Ana Rita; Cavadas, Cláudia, Trends in Endocrinology & Metabolism. 2024. http://dx.doi.org/10.1016/j.tem.2024.01.001 . 10.1016/j.tem.2024.01.001 . published Trends in Endocrinology & Metabolism
Understanding neuron-glia crosstalk and biological clocks in insomnia
Catarina Carvalhas-Almeida; Joana Serra; Joaquim Moita; Cláudia Cavadas; Ana Rita Álvaro, Neuroscience & Biobehavioral Reviews. 2023. https://doi.org/10.1016/j.neubiorev.2023.105100 . 10.1016/j.neubiorev.2023.105100 . Neuroscience & Biobehavioral Reviews
The impact of insomnia on frailty and the hallmarks of aging
Catarina Carvalhas-Almeida; Cláudia Cavadas; Ana Rita Álvaro, Aging Clinical and Experimental Research. 2022. https://doi.org/10.1007/s40520-022-02310-w . 10.1007/s40520-022-02310-w . Aging Clinical and Experimental Research
Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis
Gaspar, Laetitia S.; Santos-Carvalho, Ana; Santos, Bárbara; Carvalhas-Almeida, Catarina; Barros-Viegas, Ana Teresa; Oliveiros, Bárbara; Donato, Helena; et al, Sleep Medicine Reviews. 64. 2022. http://dx.doi.org/10.1016/j.smrv.2022.101659 . 10.1016/j.smrv.2022.101659 . Sleep Medicine Reviews
Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases
Brás, João; Henriques, Daniel; Moreira, Ricardo; Santana, Magda M.; Silva-Pedrosa, Rita; Adão, Diana; Braz, Sandra; et al, Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-16369-y . 10.1038/s41598-022-16369-y . Scientific Reports
The NutriClock Study Protocol - Assessing the Impact of a Chrononutrition Intervention in Patients With Cardiometabolic Disturbances
Lages, Marlene; Gaspar, Laetitia; Carmo-Silva, Sara; Frontini, Roberta; Álvaro, Ana; Cavadas, Cláudia; Fonseca, Rui; et al, Current Developments in Nutrition. 468 - 468. Supplement. 5. 2021. http://dx.doi.org/10.1093/cdn/nzab039_004 . 10.1093/cdn/nzab039_004 . Current Developments in Nutrition
Copper impair autophagy on zebrafish (Danio rerio) gill epithelium
Luzio, A.; Parra, S.; Costa, B.; Santos, D.; Álvaro, A.R.; Monteiro, S.M., Environmental Toxicology and Pharmacology. 86. 2021. http://dx.doi.org/10.1016/j.etap.2021.103674 . 10.1016/j.etap.2021.103674 . published Environmental Toxicology and Pharmacology
Effects of short-term exposure to genistein and overfeeding diet on the neural and retinal progenitor competence of adult zebrafish (Danio rerio)
Luzio, A.; Figueiredo, M.; Matos, M.M.; Coimbra, A.M.; Álvaro, A.R.; Monteiro, S.M., Neurotoxicology and Teratology. 88. 2021. http://dx.doi.org/10.1016/j.ntt.2021.107030 . 10.1016/j.ntt.2021.107030 . published Neurotoxicology and Teratology
Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?
Gaspar, Laetitia S.; Sousa, Cátia; Álvaro, Ana Rita; Cavadas, Cláudia; Mendes, Alexandrina Ferreira, Pharmacological Research. 164. 2021. http://dx.doi.org/10.1016/j.phrs.2020.105369 . 10.1016/j.phrs.2020.105369 . Pharmacological Research
Long-term Continuous Positive Airway Pressure Treatment Ameliorates Biological Clock Disruptions in Obstructive Sleep Apnea
C014-4DE9-206C; Janina Hesse; Müge Yalçin; 0F1A-8AFD-63A0; Catarina Carvalhas-Almeida; Mafalda Ferreira; B01F-45DC-F6D7; et al, Ebiomedicine. 2021. in press Ebiomedicine
The Superpowers of Our Sleep
Gaspar, Laetitia S.; Santos, Bárbara; Barros-Viegas, Ana Teresa; Cardoso, João; Varela Amaral, Sara; Carvalhas-Almeida, Catarina; Santos-Carvalho, Ana; Cavadas, Cláudia; Álvaro, Ana Rita, Frontiers for Young Minds. 8. 2020. http://dx.doi.org/10.3389/frym.2020.540052 . 10.3389/frym.2020.540052 . Frontiers for Young Minds
The importance of determining circadian parameters in pharmacological studies
Laetitia S. Gaspar; Ana Rita Álvaro; Sara Carmo-Silva; Alexandrina Ferreira Mendes; Angela Relógio; Cláudia Cavadas, British Journal of Pharmacology. 2827 - 2847. 16. 176. 2019. https://doi.org/10.1111/bph.14712 . 10.1111/bph.14712 . British Journal of Pharmacology
Loss of hierarchical imprinting regulation at the Prader-Willi/Angelman syndrome locus in human iPSCs.
Pólvora-Brandão D; Joaquim M; Godinho I; Aprile D; Álvaro AR; Onofre I; Raposo AC; et al, Human molecular genetics. 2018. http://europepmc.org/abstract/med/30102380 . 10.1093/hmg/ddy274 . Human molecular genetics
Obstructive Sleep Apnea and Hallmarks of Aging
Gaspar, L.S.; Álvaro, A.R.; Moita, J.; Cavadas, C., Trends in Molecular Medicine. 675 - 692. 8. 23. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85025131167&partnerID=MN8TOARS . 10.1016/j.molmed.2017.06.006 . Trends in Molecular Medicine
Copper induced apoptosis in Caco-2 and Hep-G2 cells: Expression of caspases 3, 8 and 9, AIF and p53
Santos, S.; Silva, A.M.; Matos, M.; Monteiro, S.M.; Álvaro, A.R., Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology. 138 - 146. 185-186. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963665511&partnerID=MN8TOARS . 10.1016/j.cbpc.2016.03.010 . Comparative Biochemistry and Physiology Part - C: Toxicology and Pharmacology
Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress
Santana, M.M.; Rosmaninho-Salgado, J.; Cortez, V.; Pereira, F.C.; Kaster, M.P.; Aveleira, C.A.; Ferreira, M.; Álvaro, A.R.; Cavadas, C., European Neuropsychopharmacology. 1753 - 1766. 10. 25. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943267584&partnerID=MN8TOARS . 10.1016/j.euroneuro.2015.06.013 . European Neuropsychopharmacology
Neuropeptide Y stimulates autophagy in hypothalamic neurons
Aveleira, Célia A.; Botelho, Mariana; Carmo-Silva, Sara; Pascoal, Jorge F.; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al, Proceedings of the National Academy of Sciences. E1642 - E1651. 13. 112. 2015. 10.1073/pnas.1416609112 . published Proceedings of the National Academy of Sciences
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
Santos-Carvalho, Ana; ¿?lvaro, Ana Rita; Martins, João; Ambrósio, António Francisco; Cavadas, Cláudia, Progress in Neurobiology. 70 - 79. Jan. 112. 2014. 10.1016/j.pneurobio.2013.10.002 . published Progress in Neurobiology
Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro
Sousa-Ferreira, L; Aveleira, C.; Botelho, M; Álvaro, Ana Rita Costa Silva; de Almeida, P.L.; Cavadas, C., PLoS One. eCollection2014 - eCollection2014. 3. 9. 2014. 10.1371/journal.pone.0088917 . published PLoS One
Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate
Santos-Carvalho, A; Elvas, F; ¿?lvaro, A R; Ambrósio, A F; Cavadas, C., Cell Death and Disease. e636 - e636. 5. 4. 2013. 10.1038/cddis.2013.160 . published Cell Death and Disease
Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons
Sousa-Ferreira, Lígia; ¿?lvaro, Ana Rita; Aveleira, Célia; Santana, Magda; Brandão, Inês; Kügler, Sebastian; Pereira de Almeida, Luís; Cavadas, Cláudia, PLoS ONE. 19745 - 19745. 5. 6. 2011. http://www.ncbi.nlm.nih.gov/pubmed/21589937 . 10.1371/journal.pone.0019745 . published PLoS ONE
Moderate Long-Term modulation of Neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats
Sousa-Ferreira, L.; Garrido, M.; Nascimento-Ferreira, I.; Nobrega, C.; Santos-Carvalho, A.; Álvaro, A.R.; Rosmaninho-Salgado, J.; et al, PLoS ONE. 7. 6. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960672953&partnerID=MN8TOARS . 10.1371/journal.pone.0022333 . PLoS ONE
Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1ß: Role of neuropeptide y and nitric oxide
Rosmaninho-Salgado, J.; Araújo, I.M.; ¿?lvaro, A.R.; Mendes, A.F.; Ferreira, L.; Grouzmann, E.; Mota, A.; et al, Journal of Neurochemistry. 911 - 922. 3. 109. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-64149092206&partnerID=MN8TOARS . 10.1111/j.1471-4159.2009.06023.x . published Journal of Neurochemistry
Neuropeptide Y inhibits [Ca 2+]i changes in rat retinal neurons through NPY Y1 , Y4 and Y5 receptors
Álvaro, Ana Rita ; Rosmaninho-Salgado, Joana; Ambrósio, António F.; Cavadas, Cláudia, Journal of Neurochemistry. 1508 - 1515. 5. 109. 2009. http://www.ncbi.nlm.nih.gov/pubmed/19344373 . 10.1111/j.1471-4159.2009.06079.x . published Journal of Neurochemistry
Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy
Álvaro, A. R.; Martins, J.; Costa, A.C.; Fernandes, E.; Carvalho, F.; Ambrósio, A.F.; Cavadas, C., Neuroscience. 97 - 105. 1. 152. 2008. http://www.ncbi.nlm.nih.gov/pubmed/18249070 . 10.1016/j.neuroscience.2007.12.027 . published Neuroscience
Neuropeptide Y stimulates retinal neural cell proliferation - involvement of nitric oxide
¿?lvaro, Ana Rita; Martins, João; Araújo, Inês M.; Rosmaninho-Salgado, Joana; Ambrósio, António F.; Cavadas, Cláudia, Journal of Neurochemistry. 2501 - 2510. 6. 105. 2008. http://www.ncbi.nlm.nih.gov/pubmed/18331583 . 10.1111/j.1471-4159.2008.05334.x . published Journal of Neurochemistry
Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization
Moreno, António J.; Oliveira, Paulo J.; Nova, Carlos D.; ¿?lvaro, Ana R.; Moreira, Renata A.; Santos, Sandra M. D.; Macedo, Tice, Journal of Biochemical and Molecular Toxicology. 53 - 61. 2. 21. 2007. http://www.ncbi.nlm.nih.gov/pubmed/17427176 . 10.1002/jbt.20159 . published Journal of Biochemical and Molecular Toxicology
Neuropeptide Y regulates catecholamine release evoked by interleukin-1ß in mouse chromaffin cells
Rosmaninho-Salgado, Joana; ¿?lvaro, Ana Rita; Grouzmann, Eric; Duarte, Emilia P.; Cavadas, Cláudia, Peptides. 310 - 314. 2. 28. 2007. http://www.ncbi.nlm.nih.gov/pubmed/17207896 . 10.1016/j.peptides.2006.11.015 . published Peptides
Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells
Rosmaninho-Salgado, J.; Araújo, I.M.; ¿?lvaro, A.R.; Duarte, E.P.; Cavadas, C.; Álvaro, A.R., Journal of Neurochemistry. 896 - 903. 3. 103. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35248895279&partnerID=MN8TOARS . 10.1111/j.1471-4159.2007.04899.x . published Journal of Neurochemistry
NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells
¿?lvaro, Ana Rita; Rosmaninho-Salgado, Joana; Santiago, Ana Raquel; Martins, João; Aveleira, Célia; Santos, Paulo F.; Pereira, Tiago; et al, Neurochemistry International. 757 - 763. 5. 50. 2007. http://www.ncbi.nlm.nih.gov/pubmed/17353067 . 10.1016/j.neuint.2007.01.010 . published Neurochemistry International
5 34 de 34 Publicações
Todos os projectos
Informação da exclusiva responsabilidade do investigador 20-04-2025 , a partir da plataforma CIÊNCIAVITAE.
2024/04/01 - 2025/03/31
Insomnia O’ clock: new technology to insomnia detection algorithm
Mapfre
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Mapfre Foundation
2023/04/01 - 2024/03/31
Sleep@aGlance - A good night under the stars
---
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: ResMed Foundation
2022/06 - 2023
Science also sleeps: raising awareness about good (and bad) sleep habits
SaS
Universidade de Coimbra Instituto de Investigação Interdisciplinar; Universidade de Coimbra Centro de Estudos Interdisciplinares do Século XX
Financiadores: Universidade de Coimbra Instituto de Investigação Interdisciplinar
2022/03 - 2023/03
Sleep2BeHappy
Sleep2BeHappy
Principal investigator
ResMed Foundation
Financiadores: ResMed Foundation
2021/01/01 -
Sleep4All
Sleep4All
Principal investigator
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: ResMed Foundation
2020 -
Saúde no Saber
Saúde no Saber
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Ciência Viva
2020 - 2023
CIBB (Center for Innovative Biomedicine & Biotechnology) - Institutional Strategic Project
UIDB/04539/2020
Researcher
Center for Innovative Biomedicine & Biotechnology
Financiadores: Fundação para a Ciência e a Tecnologia, I.P.
2018/06/01 - 2021/12/31
NiNjA - New Neuroendocrine Strategy for healthy Aging.
PTDC/MED-FAR/30167/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2018/04/01 - 2019/03/31
SleepApnea ID
CENTRO-01-0246-FEDER-000017
Principal investigator
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Universidade de Coimbra
2018/07/06 - 2021/07/05
A detecção precoce da Apneia do Sono como uma nova estratégia para atrasar o envelhecimento
PTDC/MEC-MCI/29002/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2018/07 - 2021/08
noOSAnoAGEING- A deteção precoce da Apneia do Sono como uma nova estratégia para atrasar o envelhecimento
POCI-01-0145-FEDER-029002
Principal investigator
Fundos Europeus para o Desenvolvimento Regional ; Fundação para a Ciência e Tecnologia
2017/03/27 -
LifeSciences ByCENTRO
CENTRO-01-0246-FEDER-000011
Researcher
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: Centro 2020
2016/09/01 - 2018/06/30
Advanced models of polyglutamine disorders (HD, SCA3, SCA7)
ModelPolyQ
Post-doc Fellow
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: EU - Joint Programme – Neurodegenerative Disease Research (JPND)
2016/01/01 - 2016/06/30
Progeria – NPY
PRF 2015-60
Post-doc Fellow
Progeria Research Foundation
Financiadores: Progeria Research Foundation
2015 - 2018
HealthyAging2020 (Institutional strategic project)
POCI-01-0145-FEDER-007440
Researcher
CNC.IBILI
2015 - 2018
HealthyAging2020 (Institutional strategic project)
POCI-01-0145-FEDER-007440
Researcher
CNC.IBILI
2014/07/15 - 2015/07/31
Projeto Mais Centro - "Aging, Stress And Chronic Diseases: From Mechanisms to Therapeutics"
CENTRO-07-ST24-FEDER-002006
Post-doc Fellow
Centro de Neurociências e Biologia Celular da Universidade de Coimbra
Financiadores: QREN and Compete
2013/01 - 2013/06
Com(s)Ciência Ambiental
Projeto Escolher Ciência - PEC 120
Researcher
Financiadores: Ciência Viva
2010/02 - 2012/09
The Neuropeptide Y (NPY) and Dipeptidyl-peptidase IV (DPPIV) as new promising targets on the adipose tissue regulation in obesity
Provided by PTCRIS: 102415
Other
Financiadores: Fundação para a Ciência e a Tecnologia, I.P.
2010/04 - 2013/07
Caloric restriction increases lifespan: role of neuropeptide Y on autophagy
99082
Post-doc Fellow
Financiadores: Fundação para a Ciência e a Tecnologia, I.P.
2007/01 - 2007/10
Avaliação da toxicidade induzida pelo ecstasy na retina de rato: estudos in vitro e in vivo
Gabinete de Apoio à Investigaç
Other
Centro de Neurociências e Biologia Celular de Coimbra
2007/01 - 2007/10
Avaliação da toxicidade induzida pelo ecstasy na retina de rato: estudos in vitro e in vivo
Gabinete de Apoio à Investigaç
Other
Centro de Neurociências e Biologia Celular de Coimbra
2007/05 - 2009/04
NPY in the retina retina: why? and what for?
PTDC/SAU-NEU/73119/2006
Other
Financiadores: Fundação para a Ciência e Tecnologia
2005/04/01 - 2008/06/30
Interacção entre catecolaminas e neuropeptídeo Y nas células cromafins humanas
POCI/SAU-FCF/60399/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Financiadores: Fundação para a Ciência e a Tecnologia
2005/04 - 2008/06
Crosstalk between catecholamines and neuropeptide Y in human chromaffin cells
Provided by PTCRIS: 60399
Other
Financiadores: Fundação para a Ciência e a Tecnologia, I.P.
5 25 de 25 projetos
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