Saúde intestinal, Doenças neurodegenerativas, Mitocôndrias, Imunidade, DAMPs, miRNAs, cccf-mtDA
Impacto dos miRNAs e ccf-mtDNA em doenças neurodegenerativas e em doenças inflamatórias intestinais
Descoberta de novos biomarcadores para o diagnóstico de doenças neurodegenerativas e de doenças inflamatórias intestinais
Esta linha de investigação centra-se no estudo de como os microRNAs (miRNAs) e o DNA mitocondrial livre circulante (ccf-mtDNA) regulam a expressão génica e atuam como moléculas sinalizadoras ao longo do eixo intestino-cérebro, influenciando doenças neurodegenerativas como a doença de Parkinson. Ao investigar miRNAs específicos envolvidos na comunicação com a microbiota intestinal e envolvidos na neuroinflamação, assim como a análise do papel do ccf-mtDNA nas respostas imunitárias e sinalização no eixo intestino-cérebro, pretendemos decifrar novos mecanismos moleculares e identificar alvos terapêuticos para mitigar a degeneração neuronal e desenvolver tratamentos inovadores para estas condições.
Esta linha de investigação também se focará na identificação de miRNAs específicos e de DNA mitocondrial livre circulante (ccf-mtDNA) como potenciais biomarcadores para a deteção precoce e monitorização da progressão da disfunção no eixo intestino-cérebro em doenças neurodegenerativas (por exemplo, Alzheimer, Parkinson) e em doenças inflamatórias intestinais (como a doença de Crohn e a colite ulcerosa). Ao analisar a expressão de miRNAs e ccf-mtDNA em doentes e modelos animais, pretendemos identificar perfis moleculares específicos associados ao início e progressão destas doenças.
A nossa estratégia de investigação inclui vários modelos experimentais (amostras humanas, linhas celulares, culturas primárias e experimentação animal), bem como diversas técnicas, incluindo análise da função celular, bioenergética e dinâmica (por exemplo, Seahorse), microscopia, citometria de fluxo e biologia molecular.
Informação sobre artigos em revista, actualizada a 16-02-2025, a partir da plataforma CIÊNCIAVITAE.
Impact of Nutrition on Gut Microbiota: Implication to Parkinson’s Disease
Sobral, Joana; Esteves, Ana Raquel; Nuno Empadinhas; Sandra Morais Cardoso, 2024. Nutrition Reviews. 2024. Manuscript ID NUTR-REV-085-NR-02-2024 . accepted Nutrition Reviews
Gut-first Parkinson’s disease is encoded by gut dysbiome
Munoz-Pinto, Mário F.; Candeias, Emanuel; Melo-Marques, Inês; Esteves, A. Raquel; Maranha, Ana; Magalhães, João D.; Carneiro, Diogo Reis; et al, 2024. Molecular Neurodegeneration. 1. 19. 2024. http://dx.doi.org/10.1186/s13024-024-00766-0 . 10.1186/s13024-024-00766-0 . Molecular Neurodegeneration
Neuronal control of microglia through the mitochondria
Pereira-Santos, A.R.; Candeias, Emanuel; Magalhães, J.D.; Empadinhas, Nuno; Esteves, A. Raquel; Cardoso, Sandra M., 2024. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2024. http://dx.doi.org/10.1016/j.bbadis.2024.167167 . 10.1016/j.bbadis.2024.167167 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Nocardia cyriacigeorgica Elicits Gut Disturbances in a Leaky Gut Model of Colitis, but Not the Harmful Cascade Leading to Gut-First Parkinson’s Disease
Magalhães, João Duarte; Candeias, Emanuel; Melo-Marques, Inês; Abreu, António E.; Pereira-Santos, Ana Raquel; Esteves, Ana Raquel; Cardoso, Sandra Morais; Empadinhas, Nuno, 2024. International Journal of Molecular Sciences. 6. 25. 2024. http://dx.doi.org/10.3390/ijms25063423 . 10.3390/ijms25063423 . International Journal of Molecular Sciences
Intestinal infection triggers mitochondria-mediated a-synuclein pathology: relevance to Parkinson’s disease
D. Magalhães, João; Candeias, Emanuel; Melo-Marques, Inês; Silva, Diana F.; Esteves, A. Raquel; Empadinhas, Nuno; Cardoso, Sandra Morais, 2023. Cellular and Molecular Life Sciences. 6. 80. 2023. http://dx.doi.org/10.1007/s00018-023-04819-3 . 10.1007/s00018-023-04819-3 . Cellular and Molecular Life Sciences
LPS-induced mitochondrial dysfunction regulates innate immunity activation and a-synuclein oligomerization in Parkinson's disease
Esteves, A. Raquel; Silva, Diana F.; Banha, Diogo; Candeias, Emanuel; Guedes, Beatriz; Cardoso, Sandra M., 2023. Redox Biology. 63. 2023. http://dx.doi.org/10.1016/j.redox.2023.102714 . 10.1016/j.redox.2023.102714 . Redox Biology
The Impact of microRNAs on Mitochondrial Function and Immunity: Relevance to Parkinson's Disease
Guedes, Beatriz F. S.; Cardoso, Sandra Morais; Esteves, Ana Raquel, 2023. Biomedicines. 5. 11. 2023. http://dx.doi.org/10.3390/biomedicines11051349 . 10.3390/biomedicines11051349 . Biomedicines
The Role of Bacteria–Mitochondria Communication in the Activation of Neuronal Innate Immunity: Implications to Parkinson’s Disease
Magalhães, João D.; Esteves, Ana Raquel; Candeias, Emanuel; Silva, Diana F.; Empadinhas, Nuno; Cardoso, Sandra Morais, 2023. International Journal of Molecular Sciences. 5. 24. 2023. http://dx.doi.org/10.3390/ijms24054339 . 10.3390/ijms24054339 . International Journal of Molecular Sciences
Parkinson's Disease: A Multisystem Disorder
Costa, Helena Nunes; Esteves, Ana Raquel; Empadinhas, Nuno; Cardoso, Sandra Morais, 2022. Neuroscience Bulletin. 2022. http://dx.doi.org/10.1007/s12264-022-00934-6 . 10.1007/s12264-022-00934-6 . Neuroscience Bulletin
Neurodegenerative Microbially-Shaped Diseases: Oxidative Stress Meets Neuroinflammation
Silva, Diana Filipa; Empadinhas, Nuno; Cardoso, Sandra Morais; Esteves, Ana Raquel, 2022. Antioxidants. 11. 11. 2022. http://dx.doi.org/10.3390/antiox11112141 . 10.3390/antiox11112141 . Antioxidants
Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
Esteves, A Raquel; Munoz-Pinto, Mário F; Nunes-Costa, Daniela; Candeias, Emanuel; Silva, Diana F; Magalhães, João D; Pereira-Santos, A Raquel; et al, 2021. Gut. gutjnl - 2021. 2021. http://dx.doi.org/10.1136/gutjnl-2021-326023 . 10.1136/gutjnl-2021-326023 . Gut
Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer’s disease features in cortical neurons
Silva, Diana F.; Candeias, Emanuel; Esteves, A. Raquel; Magalhães, João D.; Ferreira, I. Luísa; Nunes-Costa, Daniela; Rego, A. Cristina; Empadinhas, Nuno; Cardoso, Sandra M., 2020. Journal of Neuroinflammation. 1. 17. 2020. http://dx.doi.org/10.1186/s12974-020-02004-y . 10.1186/s12974-020-02004-y . Journal of Neuroinflammation
Differential protein expression in diverse brain areas of Parkinson’s and Alzheimer’s disease patients
Esteves, A. R.; Cardoso, S. M., 2020. Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-70174-z . 10.1038/s41598-020-70174-z . accepted Scientific Reports
THE MITORIBOSOME: A WORLD OF OPPORTUNITIES FOR MITOCHONDRIAL DYSFUNCTION TOWARD PARKINSON’S DISEASE
Gonçalves, A Mafalda; Pereira-Santos, A Raquel; Esteves, A. Raquel; Cardoso, Sandra Morais; Empadinhas, Nuno, 2020. Antioxidants & Redox Signaling. 2020. http://dx.doi.org/10.1089/ars.2019.7997 . 10.1089/ars.2019.7997 . published Antioxidants & Redox Signaling
The Role of Beclin-1 Acetylation on Autophagic Flux in Alzheimer’s Disease
Esteves, A. Raquel; Filipe, Filipa; Magalhães, João D.; Silva, Diana F.; Cardoso, Sandra M., 2019. Molecular Neurobiology. 5654 - 5670. 8. 56. 2019. http://dx.doi.org/10.1007/s12035-019-1483-8 . 10.1007/s12035-019-1483-8 . Molecular Neurobiology
Acetylation as a major determinant to microtubule-dependent autophagy: Relevance to Alzheimer's and Parkinson disease pathology
Esteves, Ana; Andreia Palma; Rui Gomes; Daniel Santos; Diana Silva; Sandra Morais Cardoso, 2019. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2019. published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Novel Tacrine-Hydroxyphenylbenzimidazole hybrids as potential multitarget drug candidates for Alzheimer's disease
Hiremathad, Asha; Keri, Rangappa S.; Esteves, A. Raquel; Cardoso, Sandra M.; Chaves, Sílvia; Santos, M. Amélia, 2018. European Journal of Medicinal Chemistry. 255 - 267. 148. 2018. http://dx.doi.org/10.1016/j.ejmech.2018.02.023 . 10.1016/j.ejmech.2018.02.023 . European Journal of Medicinal Chemistry
Hydroxypyridinone-benzofuran hybrids with potential protective roles for Alzheimer´s disease therapy
Hiremathad, Asha; Chand, Karam; Tolayan, Lori; Rajeshwari; Keri, Rangappa S.; Esteves, A. Raquel; Cardoso, Sandra M.; Chaves, Sílvia; Santos, M. Amélia, 2018. Journal of Inorganic Biochemistry. 82 - 96. 179. 2018. http://dx.doi.org/10.1016/j.jinorgbio.2017.11.015 . 10.1016/j.jinorgbio.2017.11.015 . Journal of Inorganic Biochemistry
Mitochondrial Metabolism Regulates Microtubule Acetylome and Autophagy Trough Sirtuin-2: Impact for Parkinson’s Disease
Esteves, Ana R.; Arduíno, Daniela M.; Silva, Diana F.; Viana, Sofia D.; Pereira, Frederico C.; Cardoso, Sandra M., 2017. Molecular Neurobiology. 1440 - 1462. 2. 55. 2017. http://dx.doi.org/10.1007/s12035-017-0420-y . 10.1007/s12035-017-0420-y . Molecular Neurobiology
LRRK2 at the Crossroad Between Autophagy and Microtubule Trafficking
Esteves, A. Raquel; Cardoso, Sandra M., 2016. The Neuroscientist. 16 - 26. 1. 23. 2016. http://dx.doi.org/10.1177/1073858415616558 . 10.1177/1073858415616558 . The Neuroscientist
Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer’s-Disease Related Pathology
Silva, D. F.; Esteves, A. R.; Oliveira, C. R.; Cardoso, S. M., 2016. Molecular Neurobiology. 4021 - 4040. 6. 54. 2016. http://dx.doi.org/10.1007/s12035-016-9951-x . 10.1007/s12035-016-9951-x . Molecular Neurobiology
LRRK2 a pivotal player in mitochondrial dynamics and lysosomal clustering: highlights to sporadic Parkinson’s disease
Ana Raquel Fernandes Esteves, 2015. Therapeutic Targets for Neurological Diseases. 2015. http://dx.doi.org/10.14800/ttnd.629 . 10.14800/ttnd.629 . published Therapeutic Targets for Neurological Diseases
LRRK2, a puzzling protein: Insights into Parkinson's disease pathogenesis
Esteves, A. Raquel; Swerdlow, Russell H.; Cardoso, Sandra M., 2014. Experimental Neurology. 206 - 216. 261. 2014. http://dx.doi.org/10.1016/j.expneurol.2014.05.025 . 10.1016/j.expneurol.2014.05.025 . Experimental Neurology
The rescue of microtubule-dependent traffic recovers mitochondrial function in Parkinson's disease
Esteves, A.R.; Gozes, I.; Cardoso, S.M., 2014. Biochimica et Biophysica Acta - Molecular Basis of Disease. 7 - 21. 1. 1842. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887706170&partnerID=MN8TOARS . 10.1016/j.bbadis.2013.10.003 . Biochimica et Biophysica Acta - Molecular Basis of Disease
The Upshot of LRRK2 Inhibition to Parkinson’s Disease Paradigm
Esteves, A. R.; G-Fernandes, M.; Santos, D.; Januário, C.; Cardoso, S. M., 2014. Molecular Neurobiology. 1804 - 1820. 3. 52. 2014. http://dx.doi.org/10.1007/s12035-014-8980-6 . 10.1007/s12035-014-8980-6 . Molecular Neurobiology
The Impact of Mitochondrial Fusion and Fission Modulation in Sporadic Parkinson’s Disease
Santos, Daniel; Esteves, A. Raquel; Silva, Diana F.; Januário, Cristina; Cardoso, Sandra M., 2014. Molecular Neurobiology. 573 - 586. 1. 52. 2014. http://dx.doi.org/10.1007/s12035-014-8893-4 . 10.1007/s12035-014-8893-4 . Molecular Neurobiology
Mitochondria drive autophagy pathology via microtubule disassembly: A new hypothesis for Parkinson disease
Arduíno, D.M.; Esteves, A.R.; Cardoso, S.M., 2013. Autophagy. 112 - 114. 1. 9. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872195238&partnerID=MN8TOARS . 10.4161/auto.22443 . Autophagy
Prodromal metabolic phenotype in MCI cybrids: Implications for Alzheimer's disease
Silva, D.F.; Santana, I.; Esteves, A.R.; Baldeiras, I.; Arduino, D.M.; Oliveira, C.R.; Cardoso, S.M., 2013. Current Alzheimer Research. 180 - 190. 2. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875000768&partnerID=MN8TOARS . 10.2174/1567205011310020008 . Current Alzheimer Research
Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease
Keri, R.S.; Quintanova, C.; Marques, S.M.; Esteves, A.R.; Cardoso, S.M.; Santos, M.A., 2013. Bioorganic and Medicinal Chemistry. 4559 - 4569. 15. 21. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879689184&partnerID=MN8TOARS . 10.1016/j.bmc.2013.05.028 . Bioorganic and Medicinal Chemistry
Mitochondrial metabolic control of microtubule dynamics impairs the autophagic pathway in Parkinson's disease
Cardoso, S.M.; Esteves, A.R.; Arduno, D.M., 2012. Neurodegenerative Diseases. 38 - 40. 1-4. 10. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860223145&partnerID=MN8TOARS . 10.1159/000332601 . Neurodegenerative Diseases
Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic
Arduíno, D.M.; Esteves, A.R.; Cortes, L.; Silva, D.F.; Patel, B.; Grazina, M.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., 2012. Human Molecular Genetics. 4680 - 4702. 21. 21. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867828156&partnerID=MN8TOARS . 10.1093/hmg/dds309 . Human Molecular Genetics
Ubiquitin proteasome system in Parkinson's disease: A keeper or a witness?
Martins-Branco, D.; Esteves, A.R.; Santos, D.; Arduino, D.M.; Swerdlow, R.H.; Oliveira, C.R.; Januario, C.; Cardoso, S.M., 2012. Experimental Neurology. 89 - 99. 2. 238. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866521159&partnerID=MN8TOARS . 10.1016/j.expneurol.2012.08.008 . Experimental Neurology
Amyloid-ß-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway
Silva, D.F.F.; Esteves, A.R.; Arduino, D.M.; Oliveira, C.R.; Cardoso, S.M., 2011. Journal of Alzheimer's Disease. 565 - 581. 3. 26. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053559887&partnerID=MN8TOARS . 10.3233/JAD-2011-110423 . Journal of Alzheimer's Disease
Mitochondrial fusion/fission, transport and autophagy in Parkinson's disease: When mitochondria get nasty
Arduíno, D.M.; Esteves, A.R.; Cardoso, S.M., 2011. Parkinson's Disease. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953286639&partnerID=MN8TOARS . 10.4061/2011/767230 . Parkinson's Disease
Mitochondria: The common upstream driver of amyloid-ß and tau pathology in Alzheimers disease
Silva, D.F.F.; Esteves, A.R.; Oliveira, C.R.; Cardoso, S.M., 2011. Current Alzheimer Research. 563 - 572. 5. 8. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79959926983&partnerID=MN8TOARS . 10.2174/156720511796391872 . Current Alzheimer Research
Therapeutic intervention at cellular quality control systems in Alzheimer's and Parkinson's diseases
Arduino, D.M.; Esteves, A.R.; Silva, D.F.F.; Martins-Branco, D.; Santos, D.; Pimentel, D.F.G.; Cardoso, S.M., 2011. Current Pharmaceutical Design. 3446 - 3459. 31. 17. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055080733&partnerID=MN8TOARS . 10.2174/138161211798072481 . Current Pharmaceutical Design
Mitochondrial dysfunction: The road to alpha-synuclein oligomerization in PD
Cardoso, S.M.; Esteves, A.R.; Arduíno, D.M.; Silva, D.F.F.; Oliveira, C.R., 2011. Parkinson's Disease. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952169319&partnerID=MN8TOARS . 10.4061/2011/693761 . Parkinson's Disease
Polymorphic variation in cytochrome oxidase subunit genes
Lu, J.; Wang, K.; Rodova, M.; Esteves, R.; Berry, D.; Lezi, E.L.; Crafter, A.; et al, 2010. Journal of Alzheimer's Disease. 141 - 154. 1. 21. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954963850&partnerID=MN8TOARS . 10.3233/JAD-2010-100123 . Journal of Alzheimer's Disease
Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer
Esteves, A.R.; Lu, J.; Rodova, M.; Onyango, I.; Lezi, E.; Dubinsky, R.; Lyons, K.E.; et al, 2010. Journal of Neurochemistry. 674 - 682. 3. 113. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950661030&partnerID=MN8TOARS . 10.1111/j.1471-4159.2010.06631.x . Journal of Neurochemistry
Microtubule depolymerization potentiates alpha-synuclein oligomerization
Esteves, A. Raquel, 2010. Frontiers in Aging Neuroscience. 1. 2010. http://dx.doi.org/10.3389/neuro.24.005.2009 . 10.3389/neuro.24.005.2009 . Frontiers in Aging Neuroscience
Dysfunctional mitochondria uphold calpain activation: Contribution to Parkinson's disease pathology
Esteves, A.R.; Arduíno, D.M.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., 2010. Neurobiology of Disease. 723 - 730. 3. 37. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-75949120541&partnerID=MN8TOARS . 10.1016/j.nbd.2009.12.011 . Neurobiology of Disease
Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease
Cardoso, S.M.; Pereira, C.F.; Moreira, P.I.; Arduino, D.M.; Esteves, A.R.; Oliveira, C.R., 2010. Experimental Neurology. 294 - 298. 2. 223. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952549554&partnerID=MN8TOARS . 10.1016/j.expneurol.2009.06.008 . Experimental Neurology
Polymorphic Variation in Cytochrome Oxidase Subunit Genes
Lu, Jianghua; Wang, Kaixuan; Rodova, Mariana; Esteves, Raquel; Berry, Diana; E, Lezi; Crafter, Adam; et al, 2010. Journal of Alzheimer's Disease. 141 - 154. 1. 21. 2010. http://dx.doi.org/10.3233/jad-2010-100123 . 10.3233/jad-2010-100123 . Journal of Alzheimer's Disease
Mitochondrial metabolism modulation: A new therapeutic approach for Parkinson's disease
Arduíno, D.M.; Esteves, A.R.; Oliveira, C.R.; Cardoso, S.M., 2010. CNS and Neurological Disorders - Drug Targets. 105 - 119. 1. 9. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949908141&partnerID=MN8TOARS . CNS and Neurological Disorders - Drug Targets
Cross-talk between mitochondria and proteasome in Parkinson’s disease pathogenesis
Branco, Diogo Martins, 2010. Frontiers in Aging Neuroscience. 2010. http://dx.doi.org/10.3389/fnagi.2010.00017 . 10.3389/fnagi.2010.00017 . Frontiers in Aging Neuroscience
Oxidative stress involvement in a-synuclein oligomerization in Parkinson's disease cybrids
Esteves, A.R.; Arduíno, D.M.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., 2009. Antioxidants and Redox Signaling. 439 - 448. 3. 11. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-58849086657&partnerID=MN8TOARS . 10.1089/ars.2008.2247 . Antioxidants and Redox Signaling
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: Relevance to Parkinson's disease
Arduíno, D.M.; Esteves, A.R.; Cardoso, S.M.; Oliveira, C.R., 2009. Neurochemistry International. 341 - 348. 5. 55. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649342203&partnerID=MN8TOARS . 10.1016/j.neuint.2009.04.004 . Neurochemistry International
ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells
Arduíno, D.M.; Raquel Esteves, A.; Filipa Domingues, A.; Pereira, C.M.F.; Cardoso, S.M.; Oliveira, C.R., 2009. BMB Reports. 719 - 724. 11. 42. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-73449102905&partnerID=MN8TOARS . BMB Reports
Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells
Domingues, A.F.; Esteves, A.R.F.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., 2008. Neurotoxicity Research. 31 - 38. 1. 13. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649157955&partnerID=MN8TOARS . 10.1007/BF03033365 . Neurotoxicity Research
Mitochondria and ubiquitin-proteasomal system interplay: Relevance to Parkinson's disease
Domingues, A.F.; Arduíno, D.M.; Esteves, A.R.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., 2008. Free Radical Biology and Medicine. 820 - 825. 6. 45. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54949100005&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2008.06.007 . Free Radical Biology and Medicine
Mitochondrial function in Parkinson’s disease cybrids containing an nt2 neuron-like nuclear background
Esteves, A. Raquel F.; Domingues, A. Filipa; Ferreira, I. Luísa; Januário, Cristina; Swerdlow, Russell H.; Oliveira, Catarina R.; Cardoso, Sandra M., 2008. Mitochondrion. 219 - 228. 3. 8. 2008. http://dx.doi.org/10.1016/j.mito.2008.03.004 . 10.1016/j.mito.2008.03.004 . Mitochondrion
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