Metabolismo, Envelhecimento e Doença

Sinalização Celular e Metabolismo na Doença

Doenças Metabólicas e Neuropsiquiátricas

Inflamação

Mitocôndria

Retículo Endoplasmático

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Líder

Paula I. Moreira

Investigador(a)


Linhas de interesse

Metabolismo, Mitocôndria em Doenças do Cérebro

Stresse do Retículo Endoplasmático (RE) e Eixo RE-Mitocôndria

Sinalização Celular e Terapêutica mediadas pela β-Secretase em Doenças associadas ao Envelhecimento

Imunidade Inata em Doenças Associadas a Inflamação

Visão Geral

A nossa missão é investigar mecanismos celulares e moleculares com potenciais aplicações no diagnóstico, prognóstico e terapia direcionada para doenças metabólicas, inflamatórias e cerebrais, usando modelos experimentais in vitro e in vivo e também amostras humanas. As principais linhas de investigação visam:

  • Elucidar o papel 1) das mitocôndrias (homeostasia, energia e sinalização) e das vias de sinalização mediadas por insulina/IGF nas alterações cerebrais associadas a patologias neurodegenerativas e metabólicas e 2) da hipóxia e do sexo biológico em eventos neurodegenerativos. Também se pretende avaliar o potencial preventivo e terapêutico de estratégias farmacológicas (ex. moduladores das mitocôndrias) e não farmacológicas (ex. (pré)condicionamento por hipóxia);
  • Esclarecer a base biológica do compromisso da resiliência celular em doenças neuropsiquiátricas, focando como distúrbios do eixo ER-mitocôndria desregulam patologicamente respostas ao stresse, metabolismo e imunidade inata, além de explorar o potencial terapêutico de recursos naturais portugueses.
  • Investigar os mecanismos de morte celular programada patológica, como necrose regulada, explorar alterações no tráfego celular que possam afetar a progressão de doença e desenvolver novos inibidores da BACE1 que atuem como modificadores seletivos multifacetados de doença, impedindo alterações cerebrais e periféricas.
  • Identificar mecanismos moleculares envolvidos na inflamação periférica e central com foco especial em macrófagos e células dendríticas e metodologias de design para avaliar se produtos químicos naturais / industriais modulam a imunidade inata para desenvolver testes laboratoriais eficientes para a triagem de novos medicamentos ou produtos potencialmente imunotóxicos.

Publicações

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Informação sobre artigos em revista, actualizada a 17-12-2023, a partir da plataforma CIÊNCIAVITAE.

Mapping the lipidome in mitochondria-associated membranes (MAMs) in an in vitro model of Alzheimer's disease

Fernandes, Tânia; Melo, Tânia; Conde, Tiago; Neves, Bruna; Domingues, Pedro; Resende, Rosa; Pereira, Cláudia F.; Moreira, Paula I.; Domingues, Maria Rosário, 2024. Journal of Neurochemistry. 2024. http://dx.doi.org/10.1111/jnc.16072 . 10.1111/jnc.16072 . Journal of Neurochemistry

Advances in the Phytochemical Characterisation and Bioactivities of Salvia aurea L. Essential Oil

Jorge Miguel Alves-Silva; Delia Maccioni; Emma Cocco; Maria José Gonçalves; Silvia Porcedda; Alessandra Piras; Maria Teresa Cruz; Lígia Salgueiro; Andrea Maxia, 2023. Plants. 2023. https://doi.org/10.3390/plants12061247 . 10.3390/plants12061247 . Plants

A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases

Tânia Fernandes; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2023. Biology. 2023. https://doi.org/10.3390/biology12030414 . 10.3390/biology12030414 . Biology

Unveiling the Chemical Composition and Biological Properties of Salvia cacaliifolia Benth. Essential Oil

Jorge M. Alves-Silva; Emma Cocco; Alessandra Piras; Maria José Gonçalves; Ana Silva; Danilo Falconieri; Silvia Porcedda; et al, 2023. Plants. 2023. https://doi.org/10.3390/plants12020359 . 10.3390/plants12020359 . Plants

Metabolic defects shared by Alzheimer's disease and diabetes: A focus on mitochondria

Cristina Carvalho; Paula I. Moreira, 2023. Current Opinion in Neurobiology. 2023. https://doi.org/10.1016/j.conb.2023.102694 . 10.1016/j.conb.2023.102694 . Current Opinion in Neurobiology

Therapeutic potential of glutaminyl cyclases: Current status and emerging trends

Coimbra, Judite R.M.; Moreira, Paula I.; Santos, Armanda E.; Salvador, Jorge A.R., 2023. Drug Discovery Today. 2023. http://dx.doi.org/10.1016/j.drudis.2023.103644 . 10.1016/j.drudis.2023.103644 . Drug Discovery Today

Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina rosmarinifolia L. Essential Oil from Portugal

Jorge M. Alves-Silva; Maria José Gonçalves; Ana Silva; Carlos Cavaleiro; Maria Teresa Cruz; Lígia Salgueiro, 2023. Antibiotics. 2023. https://doi.org/10.3390/antibiotics12010179 . 10.3390/antibiotics12010179 . Antibiotics

Current Advances in Mitochondrial Targeted Interventions in Alzheimer's Disease

Tiago Sousa; Paula I. Moreira; Susana Cardoso, 2023. Biomedicines. 2023. https://doi.org/10.3390/biomedicines11092331 . 10.3390/biomedicines11092331 . Biomedicines

Exploiting the Integrated Valorization of Eucalyptus globulus Leaves: Chemical Composition and Biological Potential of the Lipophilic Fraction before and after Hydrodistillation

Cátia. S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2023. International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24076226 . 10.3390/ijms24076226 . International Journal of Molecular Sciences

Exploiting the Integrated Valorization of Eucalyptus globulus Leaves: Chemical Composition and Biological Potential of the Lipophilic Fraction before and after Hydrodistillation

Cátia. S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2023. International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24076226 . 10.3390/ijms24076226 . International Journal of Molecular Sciences

CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell Activation and Th1 Polarization

Ana Isabel Sebastião; Daniela Mateus; Mylène A. Carrascal; Cátia Sousa; Luísa Cortes; Martin F. Bachmann; Anália do Carmo; et al, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15030825 . 10.3390/pharmaceutics15030825 . Pharmaceutics

Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells

B.J. Conti; K.B. Santiago; E.O. Cardoso; F.L. Conte; M.A. Golim; M.T. Cruz; J.M. Sforcin, 2023. Brazilian Journal of Medical and Biological Research. 2023. https://doi.org/10.1590/1414-431x2023e12659 . 10.1590/1414-431x2023e12659 . Brazilian Journal of Medical and Biological Research

A Hydrophilic Sulfated Resveratrol Derivative for Topical Application: Sensitization and Anti-Allergic Potential

Ana Jesus; Ana I. Sebastião; Gonçalo Brites; Marta Correia-da-Silva; Honorina Cidade; Maria T. Cruz; Emília Sousa; Isabel F. Almeida, 2023. Molecules. 2023. https://doi.org/10.3390/molecules28073158 . 10.3390/molecules28073158 . Molecules

How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies

Ana Torres; Liliana Rego; Márcia S. Martins; Marta S. Ferreira; Maria T. Cruz; Emília Sousa; Isabel F. Almeida, 2023. Pharmaceuticals. 2023. https://doi.org/10.3390/ph16040573 . 10.3390/ph16040573 . Pharmaceuticals

Polysaccharide-Based Carriers for Pulmonary Insulin Delivery: The Potential of Coffee as an Unconventional Source

Sara A. Valente; Guido R. Lopes; Isabel Ferreira; Miguel F. Galrinho; Margarida Almeida; Paula Ferreira; Maria T. Cruz; Manuel A. Coimbra; Cláudia P. Passos, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15041213 . 10.3390/pharmaceutics15041213 . Pharmaceutics

Effect of Thymbra capitata (L.) Cav. on Inflammation, Senescence and Cell Migration

Jorge M. Alves-Silva; Sónia Pedreiro; Carlos Cavaleiro; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2023. Nutrients. 2023. https://doi.org/10.3390/nu15081930 . 10.3390/nu15081930 . Nutrients

An integrated green process for the extraction of triterpenic acids from Eucalyptus globulus leaves after hydrodistillation

Cátia S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Alexandre Gaspar; Carlos Pascoal Neto; Paula C. R. O. Pinto; et al, 2023. RSC Sustainability. 2023. https://doi.org/10.1039/D3SU00076A . 10.1039/D3SU00076A . RSC Sustainability

Antioxidants in Sunscreens: Which and What For?

Ana Jesus; Sandra Mota; Ana Torres; Maria T. Cruz; Emília Sousa; Isabel F. Almeida; Honorina Cidade, 2023. Antioxidants. 2023. https://doi.org/10.3390/antiox12010138 . 10.3390/antiox12010138 . Antioxidants

A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases

Tânia Fernandes; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2023. Biology. 2023. https://doi.org/10.3390/biology12030414 . 10.3390/biology12030414 . Biology

Effect of Ferulago lutea (Poir.) Grande Essential Oil on Molecular Hallmarks of Skin Aging

Jorge M. Alves-Silva; Patrícia Moreira; Carlos Cavaleiro; Cláudia Pereira; Maria Teresa Cruz; Lígia Salgueiro, 2023. Plants. 2023. https://doi.org/10.3390/plants12213741 . 10.3390/plants12213741 . Plants

Redox signalling and proteostasis in neurodegeneration: In vivo effects of the mitochondria-targeted antioxidant MitoQ in Huntington's disease mice

Pinho, Brígida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M.A., 2023. Free Radical Biology and Medicine. S5 - S6. 198. 2023. http://dx.doi.org/10.1016/j.freeradbiomed.2022.12.030 . 10.1016/j.freeradbiomed.2022.12.030 . Free Radical Biology and Medicine

The Effect of Curcumin-Loaded Glucan Nanoparticles on Immune Cells: Size as a Critical Quality Attribute

Mariana Colaço; Tiago Roquito; João Panão Costa; Maria Teresa Cruz; Olga Borges, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15020623 . 10.3390/pharmaceutics15020623 . Pharmaceutics

Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease

Batista, Ana; Guimarães, Pedro; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Serranho, Pedro; Bernardes, Rui, 2023. Frontiers in Aging Neuroscience. 15. 2023. http://dx.doi.org/10.3389/fnagi.2023.1161847 . 10.3389/fnagi.2023.1161847 . Frontiers in Aging Neuroscience

Retinal imaging in animal models: Searching for biomarkers of neurodegeneration

Batista, Ana; Guimarães, Pedro; Serranho, Pedro; Nunes, Ana; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; et al, 2023. Frontiers in Ophthalmology. 3. 2023. http://dx.doi.org/10.3389/fopht.2023.1156605 . 10.3389/fopht.2023.1156605 . Frontiers in Ophthalmology

Chemical composition and effect against skin alterations of bioactive extracts obtained by the hydrodistillation of Eucalyptus globulus leaves

2022. Pharmaceutics. 2022. accepted Pharmaceutics

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

Pereira, Ana Catarina; De Pascale, Jessica; Resende, Rosa; Cardoso, Susana; Ferreira, Isabel; Neves, Bruno Miguel; Carrascal, Mylène A.; et al, 2022. Cellular and Molecular Life Sciences. 4. 79. 2022. http://dx.doi.org/10.1007/s00018-022-04211-7 . 10.1007/s00018-022-04211-7 . Cellular and Molecular Life Sciences

Protective role of Portuguese natural mineral waters on skin aging: in vitro evaluation of anti-senescence and anti-oxidant properties.

Vaz CV; Oliveira AS; Silva A; Cortes L; Correia S; Ferreira R; Breitenfeld L; et al, 2022. International journal of biometeorology. 2022. http://europepmc.org/abstract/med/35994120 . 10.1007/s00484-022-02345-8 . International journal of biometeorology

Hypoxic preconditioning averts sporadic Alzheimer’s disease-like phenotype in rats: a focus on mitochondria

Correia, Sónia C.; Alves, Marco G.; Oliveira, Pedro F.; Casadesus, Gemma; LaManna, Joseph; Perry, George; Moreira, Paula I., 2022. Antioxidants & Redox Signaling. 2022. http://dx.doi.org/10.1089/ars.2019.8007 . 10.1089/ars.2019.8007 . Antioxidants & Redox Signaling

Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease

Guimarães, Pedro; Serranho, Pedro; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui, 2022. Frontiers in Aging Neuroscience. 14. 2022. http://dx.doi.org/10.3389/fnagi.2022.832195 . 10.3389/fnagi.2022.832195 . Frontiers in Aging Neuroscience

Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1a/SIRT3 Pathway

Antónia Diniz; Marco G. Alves; Emanuel Candeias; Ana I. Duarte; Paula I. Moreira; Branca M. Silva; Pedro F. Oliveira; Luís Rato, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23168912 . 10.3390/ijms23168912 . International Journal of Molecular Sciences

Longitudinal OCT texture analysis to assess the retinal changes in the triple-transgenic mouse model of Alzheimer's disease

Bernardes, Rui; Ghalati, Maryam; Ferreira, Hugo; Martins, João; Guimarães, Pedro; Moreira, Paula; Ambrósio, António; Castelo-Branco, Miguel; Serranho, Pedro, 2022. Acta Ophthalmologica. S275. 100. 2022. http://dx.doi.org/10.1111/j.1755-3768.2022.0173 . 10.1111/j.1755-3768.2022.0173 . Acta Ophthalmologica

Stage-independent biomarkers for Alzheimer’s disease from the living retina: an animal study

Ferreira, Hugo; Serranho, Pedro; Guimarães, Pedro; Trindade, Rita; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Bernardes, Rui, 2022. Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-18113-y . 10.1038/s41598-022-18113-y . Scientific Reports

Recent Trends on UV filters

Ana Jesus; Inês Augusto; Joana Duarte; Emília Sousa; Honorina Cidade; Maria T. Cruz; José M. Sousa Lobo; Isabel F. Almeida, 2022. Applied Sciences. 2022. https://doi.org/10.3390/app122312003 . 10.3390/app122312003 . Applied Sciences

Development of colorimetric cellulose-based test-strip for the rapid detection of antibodies against SARS-CoV2 virus.

Cruz MT, 2022. Cellulose (London, England). 2022. https://europepmc.org/articles/PMC9483301 . 10.1007/s10570-022-04808-y . Cellulose (London, England)

Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer’s disease: Past, present and future

2022. Ageing Research Reviews. 101612 - 101612. 77. 2022. http://dx.doi.org/10.1016/j.arr.2022.101612 . 10.1016/j.arr.2022.101612 . Ageing Research Reviews

Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes

2022. Phytomedicine Plus. 100231 - 100231. 2. 2. 2022. http://dx.doi.org/10.1016/j.phyplu.2022.100231 . 10.1016/j.phyplu.2022.100231 . Phytomedicine Plus

Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes

Pereira, Ana Catarina; Madeira, Nuno; Morais, Sofia; Macedo, António; Cruz, Maria Teresa; Pereira, Cláudia M. F., 2022. Cells. 3. 11. 2022. http://dx.doi.org/10.3390/cells11030433 . 10.3390/cells11030433 . accepted Cells

Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes

Conte, Fernanda Lopes; Pereira, Ana Catarina; Brites, Gonçalo; Ferreira, Isabel; Silva, Ana Cristina; Sebastião, Ana Isabel; Matos, Patrícia; et al, 2022. Phytomedicine Plus. 2. 2. 2022. http://dx.doi.org/10.1016/j.phyplu.2022.100231 . 10.1016/j.phyplu.2022.100231 . Phytomedicine Plus

Bioactive Bacterial Nanocellulose Membranes Enriched with Eucalyptus globulus Labill. Leaves Aqueous Extract for Anti-Aging Skin Care Applications

Almeida, Tânia; Moreira, Patrícia; Sousa, Fábio J.; Pereira, Cláudia; Silvestre, Armando J. D.; Vilela, Carla; Freire, Carmen S. R., 2022. Materials. 5. 15. 2022. http://dx.doi.org/10.3390/ma15051982 . 10.3390/ma15051982 . published Materials

Chemical Composition and Effect against Skin Alterations of Bioactive Extracts Obtained by the Hydrodistillation of <i>Eucalyptus globulus</i> Leaves

Patrícia Moreira; Fábio J. Sousa; Patrícia Matos; Brites, G; Maria José Gonçalves; Carlos Cavaleiro; Artur Figueirinha; et al, 2022. Pharmaceutics. 2022. https://www.mdpi.com/1999-4923/14/3/561 . 10.3390/pharmaceutics14030561 . Pharmaceutics

Synergistic hypoglycemic and hypolipidemic effects of ¿-3 and ¿-6 fatty acids from Indian flax and sesame seed oils in streptozotocin-induced diabetic rats

Sunil Chikkalakshmipura Gurumallu; Tareq N. AlRamadneh; Halugudde Nagaraja Sarjan; Ashwini Bhaskar; Cláudia Maria Fragão Pereira; Rajesha Javaraiah, 2022. Phytomedicine Plus. 2022. https://doi.org/10.1016/j.phyplu.2022.100284 . 10.1016/j.phyplu.2022.100284 . Phytomedicine Plus

Forest Biomass as a Promising Source of Bioactive Essential Oil and Phenolic Compounds for Alzheimer’s Disease Therapy

Patrícia Moreira; Patrícia Matos; Artur Figueirinha; Lígia Salgueiro; Maria Teresa Batista; Pedro Costa Branco; Maria Teresa Cruz; Cláudia Fragão Pereira, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23158812 . 10.3390/ijms23158812 . International Journal of Molecular Sciences

UV Filters: Challenges and Prospects

Ana Jesus; Emília Sousa; Maria T. Cruz; Honorina Cidade; José M. Sousa Lobo; Isabel F. Almeida, 2022. Pharmaceuticals. 263 - 263. 3. 15. 2022. https://doi.org/10.3390/ph15030263 . 10.3390/ph15030263 . Pharmaceuticals

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

2022. Cellular and Molecular Life Sciences. 4. 79. 2022. http://dx.doi.org/10.1007/s00018-022-04211-7 . 10.1007/s00018-022-04211-7 . Cellular and Molecular Life Sciences

WWOX inhibition by Zfra1-31 restores mitochondrial homeostasis and viability of neuronal cells exposed to high glucose

Cristina Carvalho; Sónia C. Correia; Raquel Seiça; Paula I. Moreira, 2022. Cellular and Molecular Life Sciences. 2022. https://doi.org/10.1007/s00018-022-04508-7 . 10.1007/s00018-022-04508-7 . Cellular and Molecular Life Sciences

Chemical Composition and Effect against Skin Alterations of Bioactive Extracts Obtained by the Hydrodistillation of <i>Eucalyptus globulus</i> Leaves

Patrícia Moreira; Fábio J. Sousa; Patrícia Matos; Brites, G; Maria José Gonçalves; Carlos Cavaleiro; Artur Figueirinha; et al, 2022. Pharmaceutics. 2022. https://www.mdpi.com/1999-4923/14/3/561 . 10.3390/pharmaceutics14030561 . Pharmaceutics

Forest Biomass as a Promising Source of Bioactive Essential Oil and Phenolic Compounds for Alzheimer’s Disease Therapy

Patrícia Moreira; Patrícia Matos; Artur Figueirinha; Lígia Salgueiro; Maria Teresa Batista; Pedro Costa Branco; Maria Teresa Cruz; Cláudia Fragão Pereira, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23158812 . 10.3390/ijms23158812 . International Journal of Molecular Sciences

Impact of Gastrointestinal Digestion on the Anti-Inflammatory Properties of Phlorotannins from Himanthalia elongata

Marcelo D. Catarino; Ana Rita Circuncisão; Bruno Neves; Catarina Marçal; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso, 2022. Antioxidants. 2022. https://doi.org/10.3390/antiox11081518 . 10.3390/antiox11081518 . Antioxidants

Lavandula viridis L ' Her. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade

Zuzarte, Monica; Francisco, Vera; Neves, Bruno; Liberal, Joana; Cavaleiro, Carlos; Canhoto, Jorge; Salgueiro, Ligia; Cruz, Maria Teresa, 2022. Frontiers in Pharmacology. 2022. https://publons.com/wos-op/publon/51702070/ . 10.3389/FPHAR.2021.695911 . Frontiers in Pharmacology

Up-to-Date Overview of the Use of Natural Ingredients in Sunscreens

Diana I. S. P. Resende; Ana Jesus; José M. Sousa Lobo; Emília Sousa; Maria T. Cruz; Honorina Cidade; Isabel F. Almeida, 2022. Pharmaceuticals. 372 - 372. 3. 15. 2022. https://doi.org/10.3390/ph15030372 . 10.3390/ph15030372 . Pharmaceuticals

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

Sofia mori, 2022. Cellular and Molecular Life Sciences. 2022. accepted Cellular and Molecular Life Sciences

The Anti-Inflammatory Response of Lavandula luisieri and Lavandula pedunculata Essential Oils

Monica Zuzarte; Cátia Sousa; Carlos Cavaleiro; Maria Teresa Cruz; Lígia Salgueiro, 2022. Plants. 2022. https://doi.org/10.3390/plants11030370 . 10.3390/plants11030370 . Plants

Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes

Ana Catarina Pereira; Nuno Madeira; Sofia Morais; António Macedo; Maria Teresa Cruz; Cláudia M. F. Pereira, 2022. Cells. 433 - 433. 3. 11. 2022. https://doi.org/10.3390/cells11030433 . 10.3390/cells11030433 . Cells

Improvement of Glycaemia and Endothelial Function by a New Low-Dose Curcuminoid in an Animal Model of Type 2 Diabetes

Sara Oliveira; Tamaeh Monteiro-Alfredo; Rita Henriques; Carlos Fontes Ribeiro; Raquel Seiça; Teresa Cruz; Célia Cabral; et al, 2022. International Journal of Molecular Sciences. 5652 - 5652. 10. 23. 2022. https://doi.org/10.3390/ijms23105652 . 10.3390/ijms23105652 . International Journal of Molecular Sciences

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Pereira, Cláudia, 2021. Autophagy. 1 - 382. 8. 2021. published Autophagy

Crosstalk between estrogen, dendritic cells, and SARS-CoV-2 infection

Mateus, Daniela; Sebastiao, Ana Isabel; Carrascal, Mylene A.; do Carmo, Analia; Matos, Ana Miguel; Cruz, Maria Teresa; Mateus, D.; et al, 2021. Reviews in Medical Virology. 2021. https://publons.com/publon/49453726/ . 10.1002/RMV.2290 . Reviews in Medical Virology

Chemical characterization and bioactive potential of Artemisia campestris L. subsp. maritima (DC) Arcang. essential oil and hydrodistillation residual water

Rocha, Maria Inês; Gonçalves, Maria José; Cavaleiro, Carlos; Cruz, Maria Teresa; Pereira, Cláudia; Moreira, Patrícia; Salgueiro, Lígia; Figueirinha, Artur, 2021. Journal of Ethnopharmacology. 276. 2021. http://dx.doi.org/10.1016/j.jep.2021.114146 . 10.1016/j.jep.2021.114146 . published Journal of Ethnopharmacology

Propolis from southeastern Brazil produced by Apis mellifera affects innate immunity by modulating cell marker expression, cytokine production and intracellular pathways in human monocytes

Conte, Fernanda Lopes; Santiago, Karina Basso; Conti, Bruno Jose; Cardoso, Eliza de Oliveira; Garcia Oliveira, Lucas Pires; Feltran, Georgia da Silva; Zambuzzi, Willian Fernando; et al, 2021. Journal of Pharmacy and Pharmacology. 135 - 144. 2. 73. 2021. https://publons.com/publon/46053419/ . 10.1093/JPP/RGAA023 . Journal of Pharmacy and Pharmacology

Exosomes as new therapeutic vectors for pancreatic cancer treatment

Oliveira, Constanca; Calmeiro, Joao; Carrascal, Mylene A.; Falcao, Amilcar; Gomes, Celia; Neves, Bruno Miguel; Cruz, Maria Teresa, 2021. European Journal of Pharmaceutics and Biopharmaceutics. 2021. https://publons.com/publon/39705379/ . 10.1016/J.EJPB.2021.02.002 . European Journal of Pharmaceutics and Biopharmaceutics

Anti-Inflammatory Activity of Calendula officinalis L. Flower Extract

Diva Silva; Marta Salvador Ferreira; José Manuel Sousa-Lobo; Maria Teresa Cruz; Isabel Filipa Almeida, 2021. Cosmetics. 2021. https://doi.org/10.3390/cosmetics8020031 . 10.3390/cosmetics8020031 . Cosmetics

Antitumor Activity of Fucus vesiculosus-Derived Phlorotannins through Activation of Apoptotic Signals in Gastric and Colorectal Tumor Cell Lines

Marcelo D. Catarino; Iva Fernandes; Hélder Oliveira; Mylene Carrascal; Rita Ferreira; Artur M. S. Silva; Maria Teresa Cruz; Nuno Mateus; Susana M. Cardoso, 2021. International Journal of Molecular Sciences. 7604 - 7604. 14. 22. 2021. https://doi.org/10.3390/ijms22147604 . 10.3390/ijms22147604 . International Journal of Molecular Sciences

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimers Disease

Fernandes, Tânia; Resende, Rosa; Silva, Diana F.; Marques, Ana P.; Santos, Armanda E.; Cardoso, Sandra M.; Domingues, M. Rosário; Moreira, Paula I.; Pereira, Cláudia F., 2021. Biomedicines. 8. 9. 2021. http://dx.doi.org/10.3390/biomedicines9080881 . 10.3390/biomedicines9080881 . published Biomedicines

Antifungal and Anti-Inflammatory Potential of Bupleurum rigidum subsp. paniculatum (Brot.) H.Wolff Essential Oil

Mónica Zuzarte; Pedro M. P. Correia; Jorge M. Alves-Silva; Maria J. Gonçalves; Carlos Cavaleiro; Teresa Cruz; Lígia Salgueiro, 2021. Antibiotics. 592 - 592. 5. 10. 2021. https://doi.org/10.3390/antibiotics10050592 . 10.3390/antibiotics10050592 . Antibiotics

Pharmacological combination of nivolumab with dendritic cell vaccines in cancer immunotherapy: An overview

Calmeiro, J.; Carrascal, M.A.; Tavares, A.R.; Ferreira, D.A.; Gomes, C.; Cruz, M.T.; Falcão, A.; et al, 2021. Pharmacological Research. 164. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85099552475&partnerID=MN8TOARS . 10.1016/j.phrs.2020.105309 . Pharmacological Research

Mitochondrial Alterations in Fibroblasts of Early Stage Bipolar Disorder Patients

Ana P. Marques; Rosa Resende; Diana F. Silva; Mariana Batista; Daniela Pereira; Brigite Wildenberg; Sofia Morais; et al, 2021. Biomedicines. 2021. https://www.mdpi.com/2227-9059/9/5/522 . 10.3390/biomedicines9050522 . Biomedicines

Chemical composition and biological activity of essential oil of Teucrium scordium L. subsp. scordioides (Schreb.) Arcang. (Lamiaceae) from Sardinia Island (Italy)

Piras, A.; Maccioni, A.; Falconieri, D.; Porcedda, S.; Gonçalves, M.J.; Alves-Silva, J.M.; Silva, A.; et al, 2021. Natural Product Research. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85121839185&partnerID=MN8TOARS . 10.1080/14786419.2021.2018432 . Natural Product Research

Therapies for Alzheimer’s disease: a metabolic perspective

Domingues, Raquel; Pereira, Claúdia; Cruz, Maria Teresa; Silva, Ana, 2021. Molecular Genetics and Metabolism. 21. S1096-71. 2021. http://dx.doi.org/10.1016/j.ymgme.2021.01.011 . 10.1016/j.ymgme.2021.01.011 . published Molecular Genetics and Metabolism

Inflammation in Bipolar Disorder (BD): Identification of new therapeutic targets

Pereira, Ana Catarina; Oliveira, Joana; Silva, Sónia; Madeira, Nuno; Pereira, Cláudia M.F.; Cruz, Maria T., 2021. Pharmacological Research. 163. 2021. http://dx.doi.org/10.1016/j.phrs.2020.105325 . 10.1016/j.phrs.2020.105325 . published Pharmacological Research

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Pinheiro, T.; Cardoso, A.R.; Sousa, C.E.A.; Marques, A.C.; Tavares, A.P.M.; Matos, A.M.; Cruz, M.T.; et al, 2021. ACS Omega. 29268 - 29290. 44. 6. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85118899020&partnerID=MN8TOARS . 10.1021/acsomega.1c04012 . ACS Omega

Therapies for Alzheimer's disease: a metabolic perspective

Domingues, R.; Pereira, C.; Cruz, M.T.; Silva, A.; Domingues, Raquel; Pereira, Claudia; Cruz, Maria Teresa; Silva, Ana, 2021. Molecular Genetics and Metabolism. 162 - 172. 3. 132. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100399064&partnerID=MN8TOARS . 10.1016/j.ymgme.2021.01.011 . Molecular Genetics and Metabolism

Chemical characterization and bioactive potential of Artemisia campestris L. subsp. maritima (DC) Arcang. essential oil and hydrodistillation residual water

Rocha, M.I.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Pereira, C.; Moreira, P.; Salgueiro, L.; et al, 2021. Journal of Ethnopharmacology. 276. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105307700&partnerID=MN8TOARS . 10.1016/j.jep.2021.114146 . Journal of Ethnopharmacology

In-Depth Analysis of the Impact of Different Serum-Free Media on the Production of Clinical Grade Dendritic Cells for Cancer Immunotherapy

Calmeiro, J.; Mendes, L.; Duarte, I.F.; Leitão, C.; Tavares, A.R.; Ferreira, D.A.; Gomes, C.; et al, 2021. Frontiers in Immunology. 11. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85101266995&partnerID=MN8TOARS . 10.3389/fimmu.2020.593363 . Frontiers in Immunology

IGF1R Deficiency Modulates Brain Signaling Pathways and Disturbs Mitochondria and Redox Homeostasis

Susana Cardoso; Icíar López; Sergio Piñeiro-Hermida; José Pichel; Paula Moreira, 2021. Biomedicines. 158 - 158. 2. 9. 2021. https://doi.org/10.3390/biomedicines9020158 . 10.3390/biomedicines9020158 . Biomedicines

WWOX: A New Therapeutic Target In Type 2 Diabetes-Associated Neurodegeneration

Carvalho, Cristina; Moreira, Paula I., 2021. Metabolism. 116. 2021. http://dx.doi.org/10.1016/j.metabol.2020.154616 . 10.1016/j.metabol.2020.154616 . Metabolism

Oxygen Sensing and Signaling in Alzheimer's Disease: A Breathtaking Story!

Sónia C. Correia; Paula I. Moreira, 2021. Cellular and Molecular Neurobiology. 2021. https://doi.org/10.1007/s10571-021-01148-6 . 10.1007/s10571-021-01148-6 . Cellular and Molecular Neurobiology

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer’s Disease

Tânia Fernandes; Rosa Resende; Diana F. Silva; Ana P. Marques; Armanda E. Santos; Sandra M. Cardoso; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2021. Biomedicines. 881 - 881. 8. 9. 2021. https://doi.org/10.3390/biomedicines9080881 . 10.3390/biomedicines9080881 . Biomedicines

Role of Coffee Caffeine and Chlorogenic Acids Adsorption to Polysaccharides with Impact on Brew Immunomodulation Effects

Cláudia P. Passos; Rita M. Costa; Sónia S. Ferreira; Guido R. Lopes; Maria T. Cruz; Manuel A. Coimbra, 2021. Foods. 2021. https://doi.org/10.3390/foods10020378 . 10.3390/foods10020378 . Foods

Insulin-Induced Recurrent Hypoglycemia Up-Regulates Glucose Metabolism in the Brain Cortex of Chemically Induced Diabetic Rats

Susana Cardoso; Paula I. Moreira, 2021. International Journal of Molecular Sciences. 2021. https://doi.org/10.3390/ijms222413470 . 10.3390/ijms222413470 . International Journal of Molecular Sciences

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; et al, 2021. Autophagy. 1 - 382. 1. 17. 2021. http://dx.doi.org/10.1080/15548627.2020.1797280 . 10.1080/15548627.2020.1797280 . Autophagy

Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's disease

Ferreira, Hugo; Martins, João; Moreira, Paula I.; Ambrósio, António Francisco; Castelo-Branco, Miguel; Serranho, Pedro; Bernardes, Rui, 2021. Aging. 2021. http://dx.doi.org/10.18632/aging.202916 . 10.18632/aging.202916 . Aging

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer's Disease

Tânia Fernandes; Rosa Resende; Diana F. Silva; Ana P. Marques; Armanda E. Santos; Sandra M. Cardoso; M. Rosário Domingues; Paula I. Moreira; Cláudia F. Pereira, 2021. Biomedicines. 881 - 881. 8. 9. 2021. https://doi.org/10.3390/biomedicines9080881 . 10.3390/biomedicines9080881 . Biomedicines

Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's Disease

Sónia C. Correia; Nuno J. Machado; Marco G. Alves; Pedro F. Oliveira; Paula I. Moreira, 2021. International Journal of Molecular Sciences. 461 - 461. 1. 22. 2021. https://doi.org/10.3390/ijms22010461 . 10.3390/ijms22010461 . International Journal of Molecular Sciences

Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do Mitochondria-Associated Membranes (MAMs) play a role?

Resende, R.; Fernandes, T.; Pereira, A.C.; De Pascale, J.; Marques, A.P.; Oliveira, P.; Morais, S.; et al, 2020. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 6. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2020.165752 . 10.1016/j.bbadis.2020.165752 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Chemical characterization and bioactivity of the essential oil from Santolina insularis, a Sardinian endemism

Alves-Silva, J.M.; Piras, A.; Porcedda, S.; Falconieri, D.; Maxia, A.; Gonçalves, M.J.; Cruz, M.T.; Salgueiro, L., 2020. Natural Product Research. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85086880740&partnerID=MN8TOARS . 10.1080/14786419.2020.1774764 . Natural Product Research

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; Martinez-de-Oliveira, José; et al, 2020. International Journal of Biometeorology. 1957 - 1968. 11. 64. 2020. http://dx.doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . published International Journal of Biometeorology

PINK1/PARKIN signalling in neurodegeneration and neuroinflammation

Quinn, Peter M. J.; Moreira, Paula I.; Ambrósio, António Francisco; Alves, C. Henrique, 2020. Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-01062-w . 10.1186/s40478-020-01062-w . published Acta Neuropathologica Communications

Evaluating Skin Sensitization Via Soft and Hard Multivariate Modeling

Silva, F.A.L.S.; Brites, G.; Ferreira, I.; Silva, A.; Miguel Neves, B.; Costa Pereira, J.L.G.F.S.; Cruz, M.T., 2020. International Journal of Toxicology. 547 - 559. 6. 39. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85089197709&partnerID=MN8TOARS . 10.1177/1091581820944395 . International Journal of Toxicology

Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer's disease

Ferreira, Hugo; Martins, João; Nunes, Ana; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António Francisco; Serranho, Pedro; Bernardes, Rui, 2020. Health and Technology. 1816 - 1821. 2020. http://dx.doi.org/10.1007/s12553-020-00413-w . 10.1007/s12553-020-00413-w . Health and Technology

Crepis vesicaria L. subsp. taraxacifolia Leaves: Nutritional Profile, Phenolic Composition and Biological Properties

Sónia Pedreiro; Sandrine da Ressurreição; Maria Lopes; Maria Teresa Cruz; Teresa Batista; Artur Figueirinha; Fernando Ramos, 2020. International Journal of Environmental Research and Public Health. 2020. https://doi.org/10.3390/ijerph18010151 . 10.3390/ijerph18010151 . International Journal of Environmental Research and Public Health

Allergic contact dermatitis: From pathophysiology to development of new preventive strategies

Gonçalo Sousa Brites; Isabel Ferreira; Ana Isabel Sebastião; Ana Silva; Mylene Carrascal; Bruno Miguel Neves; Maria T. Cruz, 2020. Pharmacological Research. 105282 - 105282. 2020. https://doi.org/10.1016/j.phrs.2020.105282 . 10.1016/j.phrs.2020.105282 . Pharmacological Research

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Ana Sofia Oliveira; Cátia Vicente Vaz; Ana Silva; Sara Correia; Raquel Ferreira; Luiza Breitenfeld; José Martinez-de-Oliveira; et al, 2020. International Journal of Biometeorology. 2020. https://doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . International Journal of Biometeorology

Characterization and cytotoxicity assessment of the lipophilic fractions of different morphological parts of acacia dealbata

Oliveira, C.S.D.; Moreira, P.; Resende, J.; Cruz, M.T.; Pereira, C.M.F.; Silva, A.M.S.; Santos, S.A.O.; Silvestre, A.J.D., 2020. International Journal of Molecular Sciences. 5. 21. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85081225500&partnerID=MN8TOARS . 10.3390/ijms21051814 . International Journal of Molecular Sciences

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Ana Silva; Marta Pereira; Mylène Carrascal; Brites, G; Neves BM; Patrícia Moreira; Rosa Resende; et al, 2020. International Journal of Molecular Sciences. 2020. https://www.mdpi.com/1422-0067/21/20/7791 . 10.3390/ijms21207791 . International Journal of Molecular Sciences

Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-¿B Signaling Pathway

Marcelo D. Catarino; Ana Silva; Maria T. Cruz; Nuno Mateus; Artur M.S. Silva; Susana M. Cardoso, 2020. International Journal of Molecular Sciences. 2020. https://doi.org/10.3390/ijms21186897 . 10.3390/ijms21186897 . International Journal of Molecular Sciences

NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify

Ana Isabel Sebastião; Isabel Ferreira; Gonçalo Brites; Ana Silva; Bruno Miguel Neves; Maria Teresa Cruz, 2020. Pharmaceutics. 867 - 867. 9. 12. 2020. https://doi.org/10.3390/pharmaceutics12090867 . 10.3390/pharmaceutics12090867 . Pharmaceutics

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, A.S.; Vaz, C.V.; Silva, A.; Ferreira, S.S.; Correia, S.; Ferreira, R.; Breitenfeld, L.; et al, 2020. Environmental Geochemistry and Health. 2039 - 2057. 7. 42. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076109661&partnerID=MN8TOARS . 10.1007/s10653-019-00473-6 . Environmental Geochemistry and Health

Giardia lamblia Decreases NF-kappa B p65(RelA) Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages

Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenco, Agata; Cruz, Maria Teresa; Martins, Joao D.; Silva, Ana; Pereira, Sonia; et al, 2020. Scientific Reports. 1. 10. 2020. https://publons.com/publon/932727/ . 10.1038/S41598-020-63231-0 . Scientific Reports

Inflammation in Bipolar Disorder (BD): Identification of New Therapeutic Targets

Ana Catarina Pereira; Joana Oliveira; Sónia Silva; Nuno Madeira; Cláudia MF Pereira; Maria T Cruz; Oliveira, Joana; et al, 2020. Pharmacological Research. 163. 2020. https://publons.com/publon/34012396/ . 10.1016/J.PHRS.2020.105325 . Pharmacological Research

Anti-inflammatory potential of Portuguese thermal waters

Silva, A.; Oliveira, A.S.; Vaz, C.V.; Correia, S.; Ferreira, R.; Breitenfeld, L.; Martinez-de-Oliveira, J.; et al, 2020. Scientific Reports. 1. 10. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097757888&partnerID=MN8TOARS . 10.1038/s41598-020-79394-9 . Scientific Reports

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

Pinho, Brígida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M.A., 2020. Free Radical Biology and Medicine. 372 - 382. 146. 2020. http://dx.doi.org/10.1016/j.freeradbiomed.2019.11.021 . 10.1016/j.freeradbiomed.2019.11.021 . Free Radical Biology and Medicine

Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors

Coimbra, Judite R. M.; Baptista, Salete J.; Dinis, Teresa C. P.; Silva, Maria M. C.; Moreira, Paula I.; Santos, Armanda E.; Salvador, Jorge A. R., 2020. Biomolecules. 4. 10. 2020. http://dx.doi.org/10.3390/biom10040535 . 10.3390/biom10040535 . Biomolecules

Texture biomarkers of Alzheimer's disease: human vs. mouse model of disease

Nunes, Ana; Ambrósio, António Francisco; Santana, Isabel; Santiago, Beatriz; Moreira, Paula; Castelo-Branco, Miguel; Bernardes, Rui, 2020. Alzheimer's Research & Therapy. 2020. submitted Alzheimer's Research & Therapy

New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AßPPß Cleavage Decreasing Amyloid-ß Production and Accumulation in Alzheimers Disease Models

Resende, Rosa; Ferreira-Marques, Marisa; Moreira, Patrícia; Coimbra, Judite R.M.; Baptista, Salete J.; Isidoro, Ciro; Salvador, Jorge A.R.; et al, 2020. Journal of Alzheimer's Disease. 1317 - 1337. 6. 70. 2020. http://dx.doi.org/10.3233/jad-200381 . 10.3233/jad-200381 . published Journal of Alzheimer's Disease

Antifungal and anti-inflammatory potential of the endangered aromatic plant Thymus albicans

Roxo, Mariana; Zuzarte, Monica; Goncalves, Maria Jose; Alves-Silva, Jorge M.; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, Ligia; et al, 2020. Scientific Reports. 1. 10. 2020. https://publons.com/publon/36630873/ . 10.1038/S41598-020-75244-W . Scientific Reports

Liraglutide Protects Against Brain Amyloid-ß1-42 Accumulation in Female Mice with Early Alzheimer's Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

Ana I. Duarte; Emanuel Candeias; Inês N. Alves; Débora Mena; Daniela F. Silva; Nuno J. Machado; Elisa J. Campos; et al, 2020. International Journal of Molecular Sciences. 2020. https://doi.org/10.3390/ijms21051746 . 10.3390/ijms21051746 . International Journal of Molecular Sciences

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Cunnane, Stephen C.; Trushina, Eugenia; Morland, Cecilie; Prigione, Alessandro; Casadesus, Gemma; Andrews, Zane B.; Beal, M. Flint; et al, 2020. Nature Reviews Drug Discovery. 2020. http://dx.doi.org/10.1038/s41573-020-0072-x . 10.1038/s41573-020-0072-x . Nature Reviews Drug Discovery

Anti-inflammatory potential of Portuguese thermal waters

Silva, A.; Oliveira, A. S.; Vaz, C. V.; Correia, S.; Ferreira, R.; Breitenfeld, L.; Martinez-de-Oliveira, J.; et al, 2020. Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-79394-9 . 10.1038/s41598-020-79394-9 . published Scientific Reports

Associations between Trace Elements and Cognitive Decline: An Exploratory 5-Year Follow-Up Study of an Elderly Cohort

Bianca Gerardo; Marina Cabral Pinto; Joana Nogueira; Paula Pinto; Agostinho Almeida; Edgar Pinto; Paula Marinho-Reis; et al, 2020. International Journal of Environmental Research and Public Health. 2020. https://doi.org/10.3390/ijerph17176051 . 10.3390/ijerph17176051 . International Journal of Environmental Research and Public Health

Characterization of the retina of the triple-transgenic mice model of Alzheimer's disease: onset and progression of the disease

Bernardes, Rui; Ferreira, Hugo; Martins, Joao; Moreira, Paula; Francisco Ambrosio, Antonio; Castelo-Branco, Miguel; Serranho, Pedro, 2020. Neurology. 2020. https://publons.com/wos-op/publon/40788837/ . Neurology

Chemical composition of Crithmum maritimum L. essential oil and hydrodistillation residual water by GC-MS and HPLC-DAD-MS/MS, and their biological activities

Jorge M. Alves-Silva; Inês Guerra; Maria José Gonçalves; Carlos Cavaleiro; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2020. Industrial Crops and Products. 112329 - 112329. 149. 2020. https://doi.org/10.1016/j.indcrop.2020.112329 . 10.1016/j.indcrop.2020.112329 . Industrial Crops and Products

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

Calmeiro, João; Carrascal, Mylène A.; Tavares, Adriana Ramos; Ferreira, Daniel Alexandre; Gomes, Célia; Falcão, Amílcar; Cruz, Maria Teresa; et al, 2020. Pharmaceutics. 2. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12020158 . 10.3390/pharmaceutics12020158 . Pharmaceutics

Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do Mitochondria-Associated Membranes (MAMs) play a role?

R. Resende; T. Fernandes; A.C. Pereira; J. De Pascale; A.P. Marques; P. Oliveira; S. Morais; et al, 2020. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 165752 - 165752. 6. 1866. 2020. https://doi.org/10.1016/j.bbadis.2020.165752 . 10.1016/j.bbadis.2020.165752 . published Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Calcium Signaling in Aging and Neurodegenerative Diseases 2019

Luísa Cortes; João Malva; Ana Cristina Rego; Cláudia F. Pereira, 2020. International Journal of Molecular Sciences. 1125 - 1125. 3. 21. 2020. https://doi.org/10.3390/ijms21031125 . 10.3390/ijms21031125 . International Journal of Molecular Sciences

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Ana Sofia Oliveira; Cátia Vicente Vaz; Ana Silva; Sara Correia; Raquel Ferreira; Luiza Breitenfeld; José Martinez-de-Oliveira; et al, 2020. International Journal of Biometeorology. 2020. https://doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . International Journal of Biometeorology

Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbata

Oliveira, Catia S. D.; Moreira, Patricia; Resende, Judite; Cruz, Maria T.; Pereira, Claudia M. F.; Silva, Artur M. S.; Santos, Sonia A. O.; Silvestre, Armando J. D., 2020. International Journal of Molecular Sciences. 2020. https://publons.com/publon/32969534/ . 10.3390/IJMS21051814 . International Journal of Molecular Sciences

APOE ¿4-TOMM40L Haplotype Increases the Risk of Mild Cognitive Impairment Conversion to Alzheimer’s Disease

Cardoso, Remy; Lemos, Carolina; Oliveiros, Bárbara; Almeida, Maria Rosário; Baldeiras, Inês; Pereira, Cláudia Fragão; Santos, Ana; et al, 2020. Journal of Alzheimer's Disease. 587 - 601. 2. 78. 2020. http://dx.doi.org/10.3233/jad-200556 . 10.3233/jad-200556 . published Journal of Alzheimer's Disease

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Silva, Ana; Pereira, Marta; Carrascal, Mylène A.; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia; Resende, Rosa; et al, 2020. International Journal of Molecular Sciences. 20. 21. 2020. http://dx.doi.org/10.3390/ijms21207791 . 10.3390/ijms21207791 . International Journal of Molecular Sciences

Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbata

Cátia S. D. Oliveira; Patrícia Moreira; Judite Resende; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2020. International Journal of Molecular Sciences. 1814 - 1830. 5. 21. 2020. https://doi.org/10.3390/ijms21051814 . 10.3390/ijms21051814 . International Journal of Molecular Sciences

Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo study

Chiquita, Samuel; Campos, Elisa J.; Castelhano, João; Ribeiro, Mário; Sereno, José; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António Francisco, 2019. Alzheimer's Research & Therapy. 1. 11. 2019. http://dx.doi.org/10.1186/s13195-019-0542-8 . 10.1186/s13195-019-0542-8 . Alzheimer's Research & Therapy

Unveiling the Antifungal Potential of Two Iberian Thyme Essential Oils: Effect on C. albicans Germ Tube and Preformed Biofilms

Alves, Melissa; Goncalves, Maria Jose; Zuzarte, Monica; Alves-Silva, Jorge M.; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, Ligia, 2019. Frontiers in Pharmacology. 2019. https://publons.com/publon/22754016/ . 10.3389/FPHAR.2019.00446 . Frontiers in Pharmacology

Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies

Pinho, Tiffany S.; Correia, Sónia C.; Perry, George; Ambrósio, António Francisco; Moreira, Paula I., 2019. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2048 - 2059. 8. 1865. 2019. http://dx.doi.org/10.1016/j.bbadis.2018.10.037 . 10.1016/j.bbadis.2018.10.037 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer's Disease: Critical Aspects to Unravel

Chiquita, Samuel; Rodrigues-Neves, Ana C.; Baptista, Filipa I.; Carecho, Rafael; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António F., 2019. Molecular Neurobiology. 5416 - 5435. 8. 56. 2019. http://dx.doi.org/10.1007/s12035-018-1461-6 . 10.1007/s12035-018-1461-6 . Molecular Neurobiology

Unveiling the bioactive potential of the essential oil of a Portuguese endemism, Santolina impressa

Alves-Silva, J.M.; Zuzarte, M.; Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Salgueiro, L.; Alves-Silva, J. M.; Goncalves, M. J.; Cruz, M. T., 2019. Journal of Ethnopharmacology. 244. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070094953&partnerID=MN8TOARS . 10.1016/j.jep.2019.112120 . Journal of Ethnopharmacology

A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

Chiquita, Samuel; Ribeiro, Mário; Castelhano, João; Oliveira, Francisco; Sereno, José; Batista, Marta; Abrunhosa, Antero; et al, 2019. Human Molecular Genetics. 2174 - 2188. 13. 28. 2019. http://dx.doi.org/10.1093/hmg/ddz045 . 10.1093/hmg/ddz045 . Human Molecular Genetics

Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer's Disease.

Moreira, PI, 2019. Advances in experimental medicine and biology. 2019. https://doi.org/10.1007/978-981-13-3540-2_9 . 10.1007/978-981-13-3540-2_9 . Advances in experimental medicine and biology

Apple Pomace Extract as a Sustainable Food Ingredient

Fernandes, Pedro A. R.; Ferreira, Sonia S.; Bastos, Rita; Ferreira, Isabel; Cruz, Maria T.; Pinto, Antonio; Coelho, Elisabete; et al, 2019. Antioxidants. 2019. https://publons.com/publon/26807092/ . 10.3390/ANTIOX8060189 . Antioxidants

The Eighth ECS Workshop on “Calcium Signaling in Aging and Neurodegenerative Diseases”

Jan Parys; C Pereira; Carlos Villalobos, 2019. International Journal of Molecular Sciences. 2019. https://www.mdpi.com/1422-0067/20/24/6263 . 10.3390/ijms20246263 . International Journal of Molecular Sciences

Is Alzheimer's disease an inflammasomopathy?

Pereira, C.F.; Santos, A.E.; Moreira, P.I.; Pereira, A.C.; Sousa, F.J.; Cardoso, S.M.; Cruz, M.T.; et al, 2019. Ageing Research Reviews. 56. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072809334&partnerID=MN8TOARS . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

The role of endoplasmic reticulum stress in the innate immune system in bipolar disorder

Pereira, A. C.; Ferreira, I.; Neves, B.; Moura, D.; Morais, S.; Madeira, N.; Macedo, A.; Cruz, M. T.; Pereira, C., 2019. European Psychiatry. 2019. https://publons.com/publon/30841015/ . European Psychiatry

Development of a curcumin derivative with hypoglycemic properties: Impact on oxidative stress and endothelial function in type 2 diabetes

Oliveira, Sara; Monteiro, Tamaeh; Henriques, Rita; Aspercada, Luis; Ribeiro, Carlos Fontes; Seica, Raquel; Cruz, Teresa; et al, 2019. European Journal of Clinical Investigation. 2019. https://publons.com/publon/30741253/ . European Journal of Clinical Investigation

An overview of glutaminyl cyclase inhibitors for Alzheimer’s disease

Coimbra, Judite RM; Sobral, Pedro JM; Santos, Armanda E; Moreira, Paula I; Salvador, Jorge AR, 2019. Future Medicinal Chemistry. 3179 - 3194. 24. 11. 2019. http://dx.doi.org/10.4155/fmc-2019-0163 . 10.4155/fmc-2019-0163 . Future Medicinal Chemistry

Is Alzheimer's disease an inflammasomopathy?

Pereira, Claudia F.; Santos, Armanda E.; Moreira, Paula I.; Pereira, Ana Catarina; Sousa, Fabio J.; Cardoso, Sandra M.; Cruz, M. Teresa, 2019. Ageing Research Reviews. 56. 2019. http://dx.doi.org/10.1016/j.arr.2019.100966 . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

Links between Cognitive Status and Trace Element Levels in Hair for an Environmentally Exposed Population: A Case Study in the Surroundings of the Estarreja Industrial Area

Cabral Pinto, Marina M. S.; Marinho-Reis, Paula; Almeida, Agostinho; Pinto, Edgar; Neves, Orquídia; Inácio, Manuela; Gerardo, Bianca; et al, 2019. International Journal of Environmental Research and Public Health. 22. 16. 2019. http://dx.doi.org/10.3390/ijerph16224560 . 10.3390/ijerph16224560 . International Journal of Environmental Research and Public Health

Post-translational modifications in brain health and disease

Correia, Sónia C.; Carvalho, Cristina; Cardoso, Susana; Moreira, Paula I., 2019. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1947 - 1948. 8. 1865. 2019. http://dx.doi.org/10.1016/j.bbadis.2019.05.006 . 10.1016/j.bbadis.2019.05.006 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer's disease?

Rodrigues-Neves, Ana Catarina; Carecho, Rafael; Baptista, Filipa; Moreira, Paula; Ambrósio, António, 2019. Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/conf.fncel.2019.01.00020 . 10.3389/conf.fncel.2019.01.00020 . Frontiers in Cellular Neuroscience

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Ferreira, Sandra Saraiva; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; et al, 2019. Environmental Geochemistry and Health. 2019. http://dx.doi.org/10.1007/s10653-019-00473-6 . 10.1007/s10653-019-00473-6 . published Environmental Geochemistry and Health

Oxidized phosphatidylserine mitigates LPS-triggered macrophage inflammatory status through modulation of JNK and NF-kB signaling cascades

Maciel, Elisabete; Neves, Bruno M.; Martins, Joao; Colombo, Simone; Cruz, Maria Teresa; Domingues, Pedro; Domingues, M. Rosario M.; Cruz, Maria Teresa, 2019. Cellular Signalling. 2019. https://publons.com/publon/20224929/ . 10.1016/J.CELLSIG.2019.04.015 . Cellular Signalling

The cellular stress response in the immune system

Pereira, Claudia; Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Morais, Sofia; Madeira, Nuno; Santos, Vitor; Macedo, Antonio; Cruz, Maria Teresa, 2019. European Journal of Clinical Investigation. 2019. https://publons.com/publon/26807090/ . European Journal of Clinical Investigation

Retinal thickness of the triple-transgenic mice model of Alzheimer's disease at the age of one month

Bernardes, Rui; Ferreira, Hugo; Martins, João; Moreira, Paula I.; Castelo-Branco, Miguel; Ambrósio, António F.; Serranho, Pedro, 2019. Acta Ophthalmologica. S263. 97. 2019. http://dx.doi.org/10.1111/j.1755-3768.2019.5467 . 10.1111/j.1755-3768.2019.5467 . Acta Ophthalmologica

Chimeric Antigenic Receptor (CAR) T Cells: A New Immunotherapeutic Strategy

Cruz, Maria Teresa; Mateus, Daniela Marques; Borges, Olga, 2019. 2019. http://revista.farmacoterapia.pt/index.php/rpf/article/view/222 . 10.25756/rpf.v11i2-3.219 .

Nanostructuring lipid carriers using Ridolfia segetum (L.) Moris essential oil

Miranda, M.; Cruz, M.T.; Vitorino, C.; Cabral, C.; Miranda, Margarida; Cruz, Maria Teresa; Vitorino, Carla; Cabral, Celia, 2019. Materials Science and Engineering C. 103. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85066465144&partnerID=MN8TOARS . 10.1016/j.msec.2019.109804 . Materials Science and Engineering C

A defined approach for skin sensitization potency integrating in silico, in chemico and in vitro cell data

Ferreira, I.; Brites, G.; Silva, A.; Cruz, M. T.; Neves, B. M., 2019. Toxicology Letters. 2019. https://publons.com/publon/26807094/ . Toxicology Letters

Diabesity and brain disturbances: A metabolic perspective

Susana Cardoso; Paula I. Moreira, 2019. Molecular Aspects of Medicine. 71 - 79. 66. 2019. https://doi.org/10.1016/j.mam.2018.10.002 . 10.1016/j.mam.2018.10.002 . Molecular Aspects of Medicine

Unveiling the antifungal potential of two iberian thyme essential oils: Effect on C. albicans germ tube and preformed biofilms

Alves, M.; Gonçalves, M.J.; Zuzarte, M.; Alves-Silva, J.M.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L., 2019. Frontiers in Pharmacology. MAY. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068820197&partnerID=MN8TOARS . 10.3389/fphar.2019.00446 . Frontiers in Pharmacology

Apple pomace extract as a sustainable food ingredient

Fernandes, P.A.R.; Ferreira, S.S.; Bastos, R.; Ferreira, I.; Cruz, M.T.; Pinto, A.; Coelho, E.; et al, 2019. Antioxidants. 6. 8. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069685332&partnerID=MN8TOARS . 10.3390/antiox8060189 . Antioxidants

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

Paiva, Rafael Almeida; Martins-Marques, Tania; Jesus, Katia; Ribeiro-Rodrigues, Teresa; Zuzarte, Monica; Silva, Ana; Reis, Liliana; et al, 2019. Journal of Cellular and Molecular Medicine. 2019. https://publons.com/publon/18866715/ . 10.1111/JCMM.14014 . Journal of Cellular and Molecular Medicine

Biomaterial-based platforms for in situ dendritic cell programming and their use in antitumor immunotherapy

Calmeiro, Joao; Carrascal, Mylene; Gomes, Celia; Falcao, Amilcar; Cruz, Maria Teresa; Neves, Bruno Miguel; Calmeiro, J.; et al, 2019. Journal for ImmunoTherapy of Cancer. 1. 7. 2019. https://publons.com/publon/22830157/ . 10.1186/S40425-019-0716-8 . Journal for ImmunoTherapy of Cancer

Development of a novel dendritic cell-based immunotherapy targeting cancer stem cells

Calmeiro, Joao; Carrascal, Mylene; Mendes, Luis; Duarte, Iola F.; Gomes, Celia; Serra, Joao; Falcao, Amilcar; Cruz, Maria Teresa; Neves, Bruno Miguel, 2019. Journal of Clinical Oncology. 2019. https://publons.com/publon/21604203/ . 10.1200/JCO.2019.37.15_SUPPL.E14009 . Journal of Clinical Oncology

Células Estaminais Pluripotentes Induzidas no Tratamento da Doença de Alzheimer

Cruz, Maria Teresa; Marinheira, Joana; Silva, Sónia; Marinheira, Joana Filipa Rodrigues, 2019. 2019. http://www.actafarmaceuticaportuguesa.com/index.php/afp/article/view/190 .

Is Alzheimer’s disease an inflammasomopathy?

Pereira, Claudia F.; Santos, Armanda E.; Moreira, Paula I.; Pereira, Ana Catarina; Sousa, Fabio J.; Cardoso, Sandra M.; Cruz, M. Teresa, 2019. Ageing Research Reviews. 56. 2019. http://dx.doi.org/10.1016/j.arr.2019.100966 . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's Disease

Ana I. Duarte; Marie Sjögren; Maria S. Santos; Catarina R. Oliveira; Paula I. Moreira; Maria Björkqvist, 2018. Scientific Reports. 1. 8. 2018. https://doi.org/10.1038/s41598-018-27121-w . 10.1038/s41598-018-27121-w . Scientific Reports

Editorial: The Physiology of Inflammation—The Final Common Pathway to Disease

Mendes, A.F.; Cruz, M.T.; Gualillo, O.; Ferreira Mendes, Alexandrina; Teresa Cruz, Maria; Gualillo, Oreste; Mendes, Alexandrina Ferreira; Cruz, Maria Teresa, 2018. Frontiers in Physiology. 9. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070433771&partnerID=MN8TOARS . 10.3389/fphys.2018.01741 . Frontiers in Physiology

Polyphenolic characterisation and bioactivity of an Oxalis pes-caprae L. leaf extract

Gaspar, M.C.; Fonseca, D.A.; Antunes, M.J.; Frigerio, C.; Gomes, N.G.M.; Vieira, M.; Santos, A.E.; et al, 2018. Natural Product Research. 732 - 738. 6. 32. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021073702&partnerID=MN8TOARS . 10.1080/14786419.2017.1335728 . Natural Product Research

New insights on the anti-inflammatory potential and safety profile of Thymus carnosus and Thymus camphoratus essential oils and their main compounds

Zuzarte, M.; Alves-Silva, J.M.; Alves, M.; Cavaleiro, C.; Salgueiro, L.; Cruz, M.T.; Zuzarte, Monica; et al, 2018. Journal of Ethnopharmacology. 10 - 17. 225. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049324707&partnerID=MN8TOARS . 10.1016/j.jep.2018.06.025 . Journal of Ethnopharmacology

Acanthus mollis L. leaves as source of anti-inflammatory and antioxidant phytoconstituents

Cruz, Maria Teresa, 2018. 2018. http://dx.doi.org/10.1080/14786419.2018.1437438 . 10.1080/14786419.2018.1437438 .

Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment

Coimbra, Judite R. M.; Marques, Daniela F. F.; Baptista, Salete J.; Pereira, Cláudia M. F.; Moreira, Paula I.; Dinis, Teresa C. P.; Santos, Armanda E.; Salvador, Jorge A. R., 2018. Frontiers in Chemistry. 6. 2018. http://dx.doi.org/10.3389/fchem.2018.00178 . 10.3389/fchem.2018.00178 . published Frontiers in Chemistry

Exosomes as adjuvants for the recombinant hepatitis B antigen: First report

Sandra Jesus; Edna Soares; Maria Teresa Cruz; Olga Borges; Jesus, Sandra; Soares, Edna; Cruz, Maria Teresa; Borges, Olga, 2018. European Journal of Pharmaceutics and Biopharmaceutics. 1 - 11. 133. 2018. https://doi.org/10.1016/j.ejpb.2018.09.029 . 10.1016/j.ejpb.2018.09.029 . European Journal of Pharmaceutics and Biopharmaceutics

Beneficial effects of white wine polyphenols-enriched diet on Alzheimer's disease-like pathology

Mendes, D.; Oliveira, M.M.; Moreira, P.I.; Coutinho, J.; Nunes, F.M.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Videira, R.A., 2018. Journal of Nutritional Biochemistry. 165 - 177. 55. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043298266&partnerID=MN8TOARS . 10.1016/j.jnutbio.2018.02.001 . Journal of Nutritional Biochemistry

O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease

Tiffany S. Pinho; Diogo M. Verde; Sónia C. Correia; Susana M. Cardoso; Paula I. Moreira, 2018. Ageing Research Reviews. 32 - 41. 46. 2018. https://doi.org/10.1016/j.arr.2018.05.003 . 10.1016/j.arr.2018.05.003 . Ageing Research Reviews

The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy

Marques-Aleixo, I.; Santos-Alves, E.; Oliveira, P.J.; Moreira, P.I.; Magalhães, J.; Ascensão, A., 2018. Biochimica et Biophysica Acta - Reviews on Cancer. 189 - 199. 2. 1869. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041805508&partnerID=MN8TOARS . 10.1016/j.bbcan.2018.01.002 . Biochimica et Biophysica Acta - Reviews on Cancer

Bioactivity of Acanthus mollis – Contribution of benzoxazinoids and phenylpropanoids

Cruz, Maria Teresa, 2018. 2018. http://dx.doi.org/10.1016/j.jep.2018.09.013 . 10.1016/j.jep.2018.09.013 .

New Insights into the Anti-Inflammatory and Antioxidant Properties of Nitrated Phospholipids

Melo, Tania; Marques, Sara S.; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, Pedro; Segundo, Marcela A.; Marques Domingues, Maria Rosario; et al, 2018. Lipids. 117 - 131. 1. 53. 2018. https://publons.com/publon/3423064/ . 10.1002/LIPD.12007 . Lipids

Impact of different GMP media in the production of dendritic cells for next-generation cancer immunotherapy: Functional and metabolic characterization

Calmeiro, J.; Carrascal, M.; Gomes, C.; Falcao, A.; Serra, J.; Cruz, M. T.; Neves, B., 2018. Annals of Oncology. 2018. https://publons.com/publon/26807098/ . Annals of Oncology

Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1

Ferreira, Isabel; Silva, Ana; Martins, Joao Demetrio; Neves, Bruno Miguel; Cruz, Maria Teresa; Cruz, Maria Teresa, 2018. Redox Biology. 2018. https://publons.com/publon/16980300/ . 10.1016/J.REDOX.2018.02.002 . Redox Biology

Sweet Mitochondria: A Shortcut to Alzheimer's Disease

Moreira, P.I., 2018. Journal of Alzheimer's Disease. 1391 - 1401. 3. 62. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044360897&partnerID=MN8TOARS . 10.3233/JAD-170931 . Journal of Alzheimer's Disease

Fingernail Trace Element Content in Environmentally Exposed Individuals and Its Influence on Their Cognitive Status in Ageing

Cabral Pinto, Marina M. S.; Marinho-Reis, A. Paula; Almeida, Agostinho; Freitas, Sandra; Simões, Mário R.; Diniz, M. Luísa; Pinto, Edgar; et al, 2018. Exposure and Health. 181 - 194. 3. 11. 2018. http://dx.doi.org/10.1007/s12403-018-0274-1 . 10.1007/s12403-018-0274-1 . Exposure and Health

Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease

Duarte, A.I.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I., 2018. Neuropharmacology. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044268663&partnerID=MN8TOARS . 10.1016/j.neuropharm.2018.01.044 . Neuropharmacology

Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells

Ana I. Plácido; Cláudia M. F. Pereira; Sónia C. Correira; Cristina Carvalho; Catarina R. Oliveira; Paula I. Moreira, 2017. Molecular Neurobiology. 2017. http://dx.doi.org/10.1007/s12035-015-9640-1 . 10.1007/s12035-015-9640-1 . Molecular Neurobiology

Inflammasome in dendritic cells immunobiology: Implications to diseases and therapeutic strategies

Ferreira, I.; Liberal, J.; Martins, J.D.; Silva, A.; Neves, B.M.; Cruz, M.T., 2017. Current Drug Targets. 1003 - 1018. 9. 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022193483&partnerID=MN8TOARS . 10.2174/1389450117666160921144830 . Current Drug Targets

In vitro macrophage nitric oxide production by Pterospartum tridentatum (L.) Willk. inflorescence polysaccharides

Martins, Vitor M. R.; Simoes, Joana; Ferreira, Isabel; Cruz, Maria Teresa; Rosario Domingues, M.; Coimbra, Manuel A.; Martins, V.M.R.; et al, 2017. Carbohydrate Polymers. 176 - 184. 157. 2017. https://publons.com/publon/953728/ . 10.1016/J.CARBPOL.2016.09.079 . Carbohydrate Polymers

Antioxidant and anti-inflammatory activities of: Geranium robertianum L. decoctions

Catarino, M.D.; Silva, A.M.S.; Cruz, M.T.; Cardoso, S.M.; Marcelo D. Catarino; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso, 2017. Food and Function. 3355 - 3365. 9. 8. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029740286&partnerID=MN8TOARS . 10.1039/c7fo00881c . Food and Function

When, where and how: mitochondrial multifaceted dysfunction in Alzheimer's disease

Oliveira, C. R.; Pereira, C.; Rego, A. C.; Moreira, P. I.; Cardoso, S., 2017. European Journal of Clinical Investigation. 24 - 25. 47. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000412099900035&KeyUID=WOS:000412099900035 . European Journal of Clinical Investigation

Insights into the human brain proteome: Disclosing the biological meaning of protein networks in cerebrospinal fluid

Bastos, P.; Ferreira, R.; Manadas, B.; Moreira, P.I.; Vitorino, R., 2017. Critical Reviews in Clinical Laboratory Sciences. 185 - 204. 3. 54. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019117156&partnerID=MN8TOARS . 10.1080/10408363.2017.1299682 . Critical Reviews in Clinical Laboratory Sciences

Contact dermatitis: in pursuit of sensitizer’s molecular targets through proteomics

Guedes, S.; Neves, B.; Vitorino, R.; Domingues, R.; Cruz, M.T.; Domingues, P.; Guedes, Sofia; et al, 2017. Archives of Toxicology. 811 - 825. 2. 91. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964645560&partnerID=MN8TOARS . 10.1007/s00204-016-1714-y . Archives of Toxicology

Assessment of safe bioactive doses of Foeniculum vulgare Mill. essential oil from Portugal

Cabral, C.; Miranda, M.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L., 2017. Natural Product Research. 2654 - 2659. 22. 31. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014579756&partnerID=MN8TOARS . 10.1080/14786419.2017.1292266 . Natural Product Research

Mitochondria as a target for neuroprotection: implications for Alzheimer´s disease

Cardoso, S.; Seiça, R.M.; Moreira, P.I., 2017. Expert Review of Neurotherapeutics. 77 - 91. 1. 17. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85003782022&partnerID=MN8TOARS . 10.1080/14737175.2016.1205488 . Expert Review of Neurotherapeutics

Uncoupling Protein 2 Inhibition Exacerbates Glucose Fluctuation-Mediated Neuronal Effects

Cardoso, S.; Seiça, R.M.; Moreira, P.I., 2017. Neurotoxicity Research. 1 - 14. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028984223&partnerID=MN8TOARS . 10.1007/s12640-017-9805-y . Neurotoxicity Research

Valorization of Lipids from Gracilaria sp through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity

da Costa, Elisabete; Melo, Tania; Moreira, Ana S. P.; Bernardo, Carina; Helguero, Luisa; Ferreira, Isabel; Cruz, Maria Teresa; et al, 2017. Marine Drugs. 2017. https://publons.com/publon/3423052/ . 10.3390/MD15030062 . Marine Drugs

Chemical Composition of Laurencia obtusa Extract and Isolation of a New C-15-Acetogenin

Esselin, Helene; Sutour, Sylvain; Liberal, Joana; Cruz, Maria Teresa; Salgueiro, Ligia; Siegler, Benjamin; Freuze, Ingrid; et al, 2017. Molecules. 2017. https://publons.com/publon/10621865/ . 10.3390/MOLECULES22050779 . Molecules

Dendritic cell-based immunotherapy: a basic review and recent advances

Constantino, Joao; Gomes, Celia; Falcao, Amilcar; Neves, Bruno Miguel; Cruz, Maria Teresa; Constantino, J.; Gomes, C.; et al, 2017. Immunologic Research. 798 - 810. 4. 65. 2017. https://publons.com/publon/9962888/ . 10.1007/S12026-017-8931-1 . Immunologic Research

Antioxidant, Anti-Inflammatory, and Analgesic Activities of Agrimonia eupatoria L. Infusion

Telmo N. Santos; Gustavo Costa; J. Pinto Ferreira; Joana Liberal; Vera Francisco; António Paranhos; Maria T. Cruz; et al, 2017. Evidence-Based Complementary and Alternative Medicine. 2017. 10.1155/2017/8309894 . Evidence-Based Complementary and Alternative Medicine

Chemical composition of Laurencia obtusa extract and isolation of a new C<inf>15</inf>-acetogenin

Esselin, H.; Sutour, S.; Libera, J.; Cruz, M.T.; Salgueiro, L.; Siegler, B.; Freuze, I.; et al, 2017. Molecules. 5. 22. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020221958&partnerID=MN8TOARS . 10.3390/molecules22050779 . Molecules

Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology

Rueli, R.H.L.H.; Torres, D.J.; Dewing, A.S.T.; Kiyohara, A.C.; Barayuga, S.M.; Bellinger, M.T.; Uyehara-Lock, J.H.; et al, 2017. Journal of Alzheimer's Disease. 749 - 762. 2. 55. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84999116043&partnerID=MN8TOARS . 10.3233/JAD-151208 . Journal of Alzheimer's Disease

Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements

Cabral Pinto, M.M.S.; Marinho-Reis, A.P.; Almeida, A.; Ordens, C.M.; Silva, M.M.V.G.; Freitas, S.; Simões, M.R.; et al, 2017. Environmental Geochemistry and Health. 1 - 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014615707&partnerID=MN8TOARS . 10.1007/s10653-017-9928-3 . Environmental Geochemistry and Health

Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

Candeias, Emanuel; Sebastião, Inês; Cardoso, Susana; Carvalho, Cristina; Santos, Maria Sancha; Oliveira, Catarina Resende; Moreira, Paula I.; Duarte, Ana I., 2017. Molecular Neurobiology. 2017. http://dx.doi.org/10.1007/s12035-017-0622-3 . 10.1007/s12035-017-0622-3 . Molecular Neurobiology

Lipophilic Fraction of Cultivated Bifurcaria bifurcata R. Ross: Detailed Composition and In Vitro Prospection of Current Challenging Bioactive Properties

Santos, Sonia A. O.; Trindade, Stephanie S.; Oliveira, Catia S. D.; Parreira, Paula; Rosa, Daniela; Duarte, Maria F.; Ferreira, Isabel; et al, 2017. Marine Drugs. 2017. https://publons.com/publon/4614900/ . 10.3390/MD15110340 . Marine Drugs

Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells

Placido, Ana I.; Pereira, Claudia M. F.; Correira, Sonia C.; Carvalho, Cristina; Oliveira, Catarina R.; Moreira, Paula I., 2017. Molecular Neurobiology. 154 - 168. 1. 54. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000392133900014&KeyUID=WOS:000392133900014 . 10.1007/s12035-015-9640-1 . Molecular Neurobiology

Lipophilic fraction of cultivated Bifurcaria bifurcata R. Ross: Detailed composition and in vitro prospection of current challenging bioactive properties

Santos, S.A.O.; Trindade, S.S.; Oliveira, C.S.D.; Parreira, P.; Rosa, D.; Duarte, M.F.; Ferreira, I.; et al, 2017. Marine Drugs. 11. 15. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85036574775&partnerID=MN8TOARS . 10.3390/md15110340 . Marine Drugs

Urolithins impair cell proliferation, arrest the cell cycle and induce apoptosis in UMUC3 bladder cancer cells

Liberal, Joana; Carmo, Analia; Gomes, Celia; Cruz, Maria Teresa; Batista, Maria Teresa; Liberal, J.; Carmo, A.; et al, 2017. Investigational New Drugs. 671 - 681. 6. 35. 2017. https://publons.com/publon/10621860/ . 10.1007/S10637-017-0483-7 . Investigational New Drugs

Valorization of lipids from Gracilaria sp. through lipidomics and decoding of antiproliferative and anti-inflammatory activity

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Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers

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Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH

Cruz, Maria Teresa, 2014. Arch Biochem Biophys. 2014. 10.1016/j.abb.2014.02.002 . Arch Biochem Biophys

Enhanced Amyloidogenic Processing of Amyloid Precursor Protein and Cell Death Under Prolonged Endoplasmic Reticulum Stress in Brain Endothelial Cells

Plácido, A.I.; Oliveira, C.R.; Moreira, P.I.; Pereira, C.M.F., 2014. Molecular Neurobiology. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905883677&partnerID=MN8TOARS . 10.1007/s12035-014-8819-1 . Molecular Neurobiology

Chemical characterization and anti-inflammatory activity of luteolin glycosides isolated from lemongrass

Cruz, Maria Teresa; Francisco, Vera; Figueirinha, Artur; Costa, Gustavo; Liberal, Joana; Lopes, Maria Celeste; Garcia-Rodriguez, Carmen; et al, 2014. Journal of Functional Foods. 436 - 443. 10. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342034200047&KeyUID=WOS:000342034200047 . doi:10.1016/j.jff.2014.07.003 . Journal of Functional Foods

Neurotensin decreases the proinflammatory status of human skin fibroblasts and increases epidermal growth factor expression.

Pereira da Silva L; Miguel Neves B; Moura L; Cruz MT; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/25180119 . 10.1155/2014/248240 .

Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes

Santos, R.X.; Correia, S.C.; Alves, M.G.; Oliveira, P.F.; Cardoso, S.; Carvalho, C.; Seiça, R.; Santos, M.S.; Moreira, P.I., 2014. Molecular and Cellular Biochemistry. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901561690&partnerID=MN8TOARS . 10.1007/s11010-014-2076-5 . Molecular and Cellular Biochemistry

Metformin in the diabetic brain: friend or foe?

Moreira, PI; Moreira, P.I., 2014. Annals of Translational Medicine. 54 - 56. 6. 2. 2014. http://dx.doi.org/10.3978/j.issn.2305-5839.2014.06.10 . 10.3978/j.issn.2305-5839.2014.06.10 . published Annals of Translational Medicine

Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats

Santos, R.X.; Correia, S.C.; Alves, M.G.; Oliveira, P.F.; Cardoso, S.; Carvalho, C.; Duarte, A.I.; Santos, M.S.; Moreira, P.I., 2014. Biochimica et Biophysica Acta - Molecular Basis of Disease. 1154 - 1166. 7. 1842. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899789863&partnerID=MN8TOARS . 10.1016/j.bbadis.2014.04.011 . Biochimica et Biophysica Acta - Molecular Basis of Disease

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease

Plácido, A.I.; Pereira, C.M.F.; Duarte, A.I.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; et al, 2014. Biochimica et Biophysica Acta - Molecular Basis of Disease. 1444 - 1453. 9. 1842. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903458925&partnerID=MN8TOARS . 10.1016/j.bbadis.2014.05.003 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status

Cardoso, S.; Carvalho, C.; Marinho, R.; Simões, A.; Sena, C.M.; Matafome, P.; Santos, M.S.; Seiça, R.M.; Moreira, P.I., 2014. Journal of Bioenergetics and Biomembranes. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901509164&partnerID=MN8TOARS . 10.1007/s10863-014-9551-2 . Journal of Bioenergetics and Biomembranes

Pre-diabetes alters testicular PGC1-a/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

Rato, L.; Duarte, A.I.; Tomás, G.D.; Santos, M.S.; Moreira, P.I.; Socorro, S.; Cavaco, J.E.; Alves, M.G.; Oliveira, P.F., 2014. Biochimica et Biophysica Acta - Bioenergetics. 335 - 344. 3. 1837. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892411578&partnerID=MN8TOARS . 10.1016/j.bbabio.2013.12.008 . Biochimica et Biophysica Acta - Bioenergetics

Metformin and male reproduction: Effects on Sertoli cell metabolism

Alves, M.G.; Martins, A.D.; Vaz, C.V.; Correia, S.; Moreira, P.I.; Oliveira, P.F.; Socorro, S., 2014. British Journal of Pharmacology. 1033 - 1042. 4. 171. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893042451&partnerID=MN8TOARS . 10.1111/bph.12522 . British Journal of Pharmacology

Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells

Fonseca, A.C.R.G.; Moreira, P.I.; Oliveira, C.R.; Cardoso, S.M.; Pinton, P.; Pereira, C.F., 2014. Molecular Neurobiology. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901537197&partnerID=MN8TOARS . 10.1007/s12035-014-8740-7 . Molecular Neurobiology

Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes

Carvalho, C.; Correia, S.C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I., 2014. Current Neurovascular Research. 330 - 339. 4. 11. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925786114&partnerID=MN8TOARS . Current Neurovascular Research

Increased susceptibility to amyloid-ß toxicity in rat brain microvascular endothelial cells under hyperglycemic conditions

Carvalho, C.; Katz, P.S.; Dutta, S.; Katakam, P.V.G.; Moreira, P.I.; Busija, D.W., 2014. Journal of Alzheimer's Disease. 75 - 83. 1. 38. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887249119&partnerID=MN8TOARS . 10.3233/JAD-130464 . Journal of Alzheimer's Disease

Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease

Monteiro-Cardoso, V.F.; Oliveira, M.M.; Melo, T.; Domingues, M.R.M.; Moreira, P.I.; Ferreiro, E.; Peixoto, F.; Videira, R.A., 2014. Journal of Alzheimer's Disease. 1375 - 1392. 4. 43. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919926803&partnerID=MN8TOARS . 10.3233/JAD-141002 . Journal of Alzheimer's Disease

Insulin as a bridge between type 2 diabetes and alzheimer disease - how anti-diabetics could be a solution for dementia

Sebastião, I.; Candeias, E.; Santos, M.S.; de Oliveira, C.R.; Moreira, P.I.; Duarte, A.I., 2014. Frontiers in Endocrinology. JUL. 5. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84905437740&partnerID=MN8TOARS . 10.3389/fendo.2014.00110 . Frontiers in Endocrinology

The effect of neurotensin in human keratinocytes--implication on impaired wound healing in diabetes.

Moura LI; Cruz MT; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/24198343 . 10.1177/1535370213510665 .

Drugs inducing T-cell mediated cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells.

Gonçalo M; Martins J; Silva A; Neves B; Cruz T; Lopes C, 2014. 2014. http://europepmc.org/abstract/PMC/PMC4128176 . 10.1186/2045-7022-4-S3-P50 .

Antifungal and anti-inflammatory claims for wild carrot essential oil

Valente, J.; Resende, R.; Zuzarte, M.; Goncalves, M. J.; Lopes, M. C.; Cavaleiro, C.; Pereira, C.; Salgueiro, L.; Cruz, M. T., 2014. Planta Medica. 1454 - 1454. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400318&KeyUID=WOS:000345550400318 . 10.1055/S-0034-1394792 . Planta Medica

Bioactivity of Fragaria vesca leaves through inflammation, proteasome and autophagy modulation.

Liberal J; Francisco V; Costa G; Figueirinha A; Amaral MT; Marques C; Girão H; et al, 2014. 2014. http://europepmc.org/abstract/med/25305515 . 10.1016/j.jep.2014.09.043 .

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease

Placido, A. I.; Pereira, C. M. F.; Duarte, A. I.; Candeias, E.; Correia, S. C.; Santos, R. X.; Carvalho, C.; et al, 2014. Biochimica Et Biophysica Acta-Molecular Basis of Disease. 1444 - 1453. 9. 1842. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340975400016&KeyUID=WOS:000340975400016 . 10.1016/j.bbadis.2014.05.003 . Biochimica Et Biophysica Acta-Molecular Basis of Disease

Protective Effect of Leptin and Ghrelin against Toxicity Induced by Amyloid- beta Oligomers in a Hypothalamic cell Line

Gomes, S.; Martins, I.; Fonseca, A. C. R. G.; Oliveira, C. R.; Resende, R.; Pereira, C. M. F., 2014. Journal of Neuroendocrinology. 176 - 185. 3. 26. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000333329700004&KeyUID=WOS:000333329700004 . 10.1111/jne.12138 . Journal of Neuroendocrinology

Loss of proteostasis induced by amyloid beta peptide in brain endothelial cells

Fonseca, Ana Catarina; Oliveira, Catarina R.; Pereira, Claudia F.; Cardoso, Sandra M., 2014. Biochimica Et Biophysica Acta-Molecular Cell Research. 1150 - 1161. 6. 1843. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000335627900010&KeyUID=WOS:000335627900010 . 10.1016/j.bbamcr.2014.02.016 . Biochimica Et Biophysica Acta-Molecular Cell Research

Antifungal and anti-inflammatory claims for wild carrot essential oil

Valente, J.; Resende, R.; Zuzarte, M.; Goncalves, M. J.; Lopes, M. C.; Cavaleiro, C.; Pereira, C.; Salgueiro, L.; Cruz, M. T., 2014. Planta Medica. 1454 - 1454. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400318&KeyUID=WOS:000345550400318 . Planta Medica

Can tea consumption be a safe and effective therapy against diabetes mellitus-induced neurodegeneration?

Nunes, A.R.; Alves, M.G.; Moreira, P.I.; Oliveira, P.F.; Silva, B.M., 2014. Current Neuropharmacology. 475 - 489. 6. 12. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84924963252&partnerID=MN8TOARS . Current Neuropharmacology

MISFOLDED BRI2 ECTODOMAIN ACTIVATES CRITICAL PATHOLOGICAL PATHWAYS INVOLVED IN EARLY STAGES OF ALZHEIMER'S DISEASE

Campo Milan, Marta Del; Pereira, Cláudia; Scheper, W.; Zwart, R.; Hoozemans, Jeroen; Oliveira, Catarina; Teunissen, Charlotte, 2014. Alzheimer's & Dementia. 4. 10. 2014. http://dx.doi.org/10.1016/j.jalz.2014.05.323 . 10.1016/j.jalz.2014.05.323 . published Alzheimer's & Dementia

Oxidative stress-dependent activation of the eIF2a-ATF4 UPR branch by skin sensitizer DNFB modulates dendritic-like cell maturation and inflammatory status in a biphasic manner.

Luís A; Martins JD; Silva A; Ferreira I; Cruz MT; Neves BM, 2014. 2014. http://europepmc.org/abstract/med/25236743 .

Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells.

Silva A; Nunes C; Martins J; Dinis TC; Lopes C; Neves B; Cruz T, 2014. 2014. http://europepmc.org/abstract/med/24742817 . 10.1016/j.freeradbiomed.2014.04.005 .

iTRAQ-based proteomic analysis of ellagitannins-enriched fraction from Fragaria vesca leaves on HepG2 cells

Liberal, J.; Costa, G.; Marques, C.; Girao, H.; Vitorino, R.; Domingues, R.; Domingues, P.; Cruz, M. T.; Batista, M. T., 2014. Planta Medica. 1438 - 1438. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400268&KeyUID=WOS:000345550400268 . 10.1055/S-0034-1394742 . Planta Medica

Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability

Pocas, J.; Lemos, M.; Cabral, C.; Cavaleiro, C.; Cruz, M. T.; Salgueiro, L.; Pires, I., 2014. Planta Medica. 1425 - 1426. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400227&KeyUID=WOS:000345550400227 . 10.1055/S-0034-1394701 . Planta Medica

Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection

Cardoso, S.; Correia, S.; Carvalho, C.; Candeias, E.; Plácido, A.I.; Duarte, A.I.; Seiça, R.M.; Moreira, P.I., 2014. Journal of Bioenergetics and Biomembranes. 119 - 131. 1-2. 47. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922536968&partnerID=MN8TOARS . 10.1007/s10863-014-9580-x . Journal of Bioenergetics and Biomembranes

Bioactive polyphenols from cork industry by-products

Ferreira, I. V.; Liberal, J.; Santos, T.; Silva, S.; Cruz, M. T.; Batista, M. T., 2014. Planta Medica. 1506 - 1506. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400477&KeyUID=WOS:000345550400477 . 10.1055/S-0034-1394951 . Planta Medica

Anti-inflammatory effects of Thymus zygis subsp sylvestris essential oil in LPS-stimulated macrophages and microglia cells

Rodrigues, V.; Cabral, C.; Evora, L.; Ferreira, I.; Pereira, C.; Cavaleiro, C.; Cruz, M. T.; Salgueiro, L., 2014. Planta Medica. 1436 - 1437. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400263&KeyUID=WOS:000345550400263 . Planta Medica

Anti-inflammatory potential of the essential oil of the Iberian endemism Thymus carnosus

Alves, M.; Zuzarte, M.; Goncalves, M. J.; Cruz, M. T.; Cavaleiro, C.; Salgueiro, L., 2014. Planta Medica. 1448 - 1448. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400299&KeyUID=WOS:000345550400299 . 10.1055/S-0034-1394773 . Planta Medica

Margotia gummifera essential oil as a source of anti-inflammatory drugs

Valente, J.; Zuzarte, M.; Liberal, J.; Gonçalves, M.J.; Lopes, M.C.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L., 2013. Industrial Crops and Products. 86 - 91. 47. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875590010&partnerID=MN8TOARS . 10.1016/j.indcrop.2013.02.036 . Industrial Crops and Products

Defective HIF signaling pathway and brain response to hypoxia in neurodegenera-tive diseases: Not an Iffy question!

Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, R.X.; Plácido, A.I.; Candeias, E.; Duarte, A.I.; Moreira, P.I., 2013. Current Pharmaceutical Design. 6809 - 6822. 38. 19. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884829985&partnerID=MN8TOARS . Current Pharmaceutical Design

Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance

Cardoso, S.; Santos, R.X.; Correia, S.C.; Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I., 2013. Neurobiology of Disease. 1 - 12. 1. 49. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866491588&partnerID=MN8TOARS . 10.1016/j.nbd.2012.08.008 . Neurobiology of Disease

Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H 2O2

González-Burgos, E.; Duarte, A.I.; Carretero, M.E.; Moreira, P.I.; Gómez-Serranillos, M.P., 2013. Journal of Natural Products. 933 - 938. 5. 76. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878260967&partnerID=MN8TOARS . 10.1021/np400118d . Journal of Natural Products

Mechanism of inhibition of mitochondrial ATP synthase by 17ß-Estradiol

Moreno, A.J.M.; Moreira, P.I.; Custódio, J.B.A.; Santos, M.S., 2013. Journal of Bioenergetics and Biomembranes. 261 - 270. 3. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878642515&partnerID=MN8TOARS . 10.1007/s10863-012-9497-1 . Journal of Bioenergetics and Biomembranes

Molecular mechanisms beyond glucose transport in diabetes-related male infertility

Alves, M.G.; Martins, A.D.; Rato, L.; Moreira, P.I.; Socorro, S.; Oliveira, P.F., 2013. Biochimica et Biophysica Acta - Molecular Basis of Disease. 626 - 635. 5. 1832. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874414576&partnerID=MN8TOARS . 10.1016/j.bbadis.2013.01.011 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Hyperglycemia, hypoglycemia and dementia: Role of mitochondria and uncoupling proteins

Cardoso, S.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Candeias, E.; Duarte, A.I.; Plácido, A.I.; Santos, M.S.; Moreira, P.I., 2013. Current Molecular Medicine. 586 - 601. 4. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876735551&partnerID=MN8TOARS . 10.2174/1566524011313040010 . Current Molecular Medicine

Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration

Duarte, A.I.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Cardoso, S.; Plácido, A.; et al, 2013. Biochimica et Biophysica Acta - Molecular Basis of Disease. 527 - 541. 4. 1832. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873306844&partnerID=MN8TOARS . 10.1016/j.bbadis.2013.01.008 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links

Perry, E.A.; Castellani, R.J.; Moreira, P.I.; Nunomura, A.; Lui, Q.; Harris, P.L.R.; Sayre, L.M.; et al, 2013. Free Radical Research. 507 - 510. 6-7. 47. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878875361&partnerID=MN8TOARS . 10.3109/10715762.2013.794265 . Free Radical Research

Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

Santos, R.X.; Correia, S.C.; Zhu, X.; Smith, M.A.; Moreira, P.I.; Castellani, R.J.; Nunomura, A.; Perry, G., 2013. Antioxidants and Redox Signaling. 2444 - 2457. 18. 18. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878619863&partnerID=MN8TOARS . 10.1089/ars.2012.5039 . Antioxidants and Redox Signaling

Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease

Correia, S.C.; Santos, R.X.; Santos, M.S.; Casadesus, G.; LaManna, J.C.; Perry, G.; Smith, M.A.; Moreira, P.I., 2013. Current Alzheimer Research. 406 - 419. 4. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878623135&partnerID=MN8TOARS . 10.2174/1567205011310040006 . Current Alzheimer Research

Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-¿B and MAPK activation in macrophages

Búfalo, Michelle Cristiane; Ferreira, Isabel; Costa, Gustavo; Francisco, Vera; Liberal, Joana; Cruz, Maria Teresa; Lopes, Maria Celeste; et al, 2013. Journal of Ethnopharmacology. 84 - 92. 1. 149. 2013. http://hdl.handle.net/10316/27433 . 10.1016/j.jep.2013.06.004 . Journal of Ethnopharmacology

Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: Potential benefits for wound healing

Moura, J.; Da Silva, L.; Cruz, M.T.; Carvalho, E., 2013. Archives of Dermatological Research. 557 - 569. 7. 305. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883240109&partnerID=MN8TOARS . 10.1007/s00403-013-1381-2 . Archives of Dermatological Research

New compounds, chemical composition, antifungal activity and cytotoxicity of the essential oil from Myrtus nivellei Batt. &amp; Trab.; An endemic species of Central Sahara

Bouzabata, A.; Bazzali, O.; Cabral, C.; Gonçalves, M.J.; Cruz, M.T.; Bighelli, A.; Cavaleiro, C.; et al, 2013. Journal of Ethnopharmacology. 613 - 620. 3. 149. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884415386&partnerID=MN8TOARS . 10.1016/j.jep.2013.06.054 . Journal of Ethnopharmacology

Type 2 diabetic and alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies

Carvalho, C.; Machado, N.; Mota, P.C.; Correia, S.C.; Cardoso, S.; Santos, R.X.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I., 2013. Journal of Alzheimer's Disease. 623 - 635. 3. 35. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880196052&partnerID=MN8TOARS . 10.3233/JAD-130005 . Journal of Alzheimer's Disease

Leishmania-infected MHC class II<sup>high</sup> dendritic cells polarize CD4<sup>+</sup> T cells toward a nonprotective T-bet<sup>+</sup> IFN-¿<sup>+</sup> IL-10<sup>+</sup> phenotype

Resende, M.; Moreira, D.; Augusto, J.; Cunha, J.; Neves, B.; Cruz, M.T.; Estaquier, J.; Cordeiro-da-Silva, A.; Silvestre, R., 2013. Journal of Immunology. 262 - 273. 1. 191. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879675210&partnerID=MN8TOARS . 10.4049/jimmunol.1203518 . Journal of Immunology

Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: Implications for Alzheimer's disease

Mondragón-Rodríguez, S.; Perry, G.; Zhu, X.; Moreira, P.I.; Acevedo-Aquino, M.C.; Williams, S., 2013. Oxidative Medicine and Cellular Longevity. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84880863640&partnerID=MN8TOARS . 10.1155/2013/940603 . Oxidative Medicine and Cellular Longevity

Ellagitannin-enriched fraction from Fragaria vesca leaves induces G2/M cell cycle arrest in the human hepatocellular carcinoma cell line HepG2

Liberal, J. T.; Costa, G.; Carmo, A.; Marques, C.; Cruz, M.; Batista, M., 2013. Planta Medica. 2013. https://publons.com/publon/26807099/ . 10.1055/S-0033-1352234 . Planta Medica

Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions

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Development of an in vitro dendritic cell-based test for skin sensitizer identification

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Mitochondria from distinct tissues are differently affected by 17ß-estradiol and tamoxifen

Moreira, P.I.; Custódio, J.B.A.; Nunes, E.; Oliveira, P.J.; Moreno, A.; Seia, R.; Oliveira, C.R.; Santos, M.S., 2011. Journal of Steroid Biochemistry and Molecular Biology. 8 - 16. 1-2. 123. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650578395&partnerID=MN8TOARS . 10.1016/j.jsbmb.2010.09.004 . Journal of Steroid Biochemistry and Molecular Biology

Oxidative Stress and Balance in Neurodegenerative Diseases

Collins, G.H.; Mondragón-Rodríguez, S.; Nunomura, A.; Zhu, X.; Moreira, P.I.; Smith, M.A., 2011. Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition. 10 - 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886036204&partnerID=MN8TOARS . 10.1002/9781444341256.ch3 . Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders: Second Edition

Effects of rapamycin and TOR on aging and memory: Implications for Alzheimer's disease

Santos, R.X.; Correia, S.C.; Cardoso, S.; Carvalho, C.; Santos, M.S.; Moreira, P.I., 2011. Journal of Neurochemistry. 927 - 936. 6. 117. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79957971392&partnerID=MN8TOARS . 10.1111/j.1471-4159.2011.07262.x . Journal of Neurochemistry

Association of mitochondrial signaling in Alzheimer's disease and hypoxia

Carvalho, C.; Correia, S.C.; Santos, R.X.; Cardoso, S.; Moreira, P.I.; Zhu, X.; Smith, M.A.; Perry, G., 2011. Molecular Aspects of Neurodegeneration and Neuroprotection. 50 - 61. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884443449&partnerID=MN8TOARS . 10.2174/978160805092511101010050 . Molecular Aspects of Neurodegeneration and Neuroprotection

New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection

Correia, S.C.; Cardoso, S.; Santos, R.X.; Carvalho, C.; Santos, M.S.; Perry, G.; Smith, M.A.; Moreira, P.I., 2011. Current Pharmaceutical Design. 3381 - 3389. 31. 17. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055089996&partnerID=MN8TOARS . 10.2174/138161211798072490 . Current Pharmaceutical Design

Mitophagy in neurodegeneration: An opportunity for therapy?

Santos, R.X.; Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, M.S.; Moreira, P.I., 2011. Current Drug Targets. 790 - 799. 6. 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955585040&partnerID=MN8TOARS . 10.2174/138945011795528813 . Current Drug Targets

Mitochondria as potential targets in antidiabetic therapy

Moreira, P.I.; Oliveira, C.R., 2011. Handbook of Experimental Pharmacology. 331 - 356. 203. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955615960&partnerID=MN8TOARS . 10.1007/978-3-642-17214-4-14 . Handbook of Experimental Pharmacology

An in vitro cell test for skin sensitizers prediction based on the analysis and integration of gene expression and signaling pathways activation

Neves, Bruno; Rosa, Susana; Martins, Joao; Goncalo, Margarida; Lopes, Maria Celeste; Cruz, Maria Teresa, 2011. Journal of Investigative Dermatology. S91 - S91. 131. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294361300538&KeyUID=WOS:000294361300538 . Journal of Investigative Dermatology

Phytochemical and biological characterization of Agrimonia eupatoria L.: an approach to structure-activity

Costa, G.; Francisco, V.; Liberal, J.; Figueirinha, A.; Cruz, T.; Figueiredo, I.; Lopes, C.; Batista, T., 2011. Planta Medica. 1420 - 1421. 12. 77. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294139000766&KeyUID=WOS:000294139000766 . 10.1055/S-0031-1282843 . Planta Medica

Anti-inflammatory properties of polyphenols from Cymbopogon citratus by inhibition of NF-kappa B pathway

Francisco, V.; Figueirinha, A.; Costa, G.; Lopes, M. C.; Garcia-Rodriguez, C.; Cruz, M. T.; Batista, M. T., 2011. Planta Medica. 1419 - 1420. 12. 77. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294139000762&KeyUID=WOS:000294139000762 . Planta Medica

Modulation of Sphingosine-1-Receptors expression by LPS and contact allergen PPD

Rosa, Susana; Neves, Bruno Miguel; Goncalo, Margarida; Domingues, Maria Rosario; Santinha, Deolinda; Macedo, Barbara; Lopes, Maria Celeste; Cruz, Maria Teresa, 2011. Journal of Investigative Dermatology. S90 - S90. 131. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294361300535&KeyUID=WOS:000294361300535 . Journal of Investigative Dermatology

Neurofilamentopathy in neurodegenerative diseases

Liu, Q.; Xie, F.; Alvarado-Diaz, A.; Smith, M.A.; Moreira, P.I.; Zhu, X.; Perry, G., 2011. Open Neurology Journal. 58 - 62. 1. 5. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80053515856&partnerID=MN8TOARS . 10.2174/1874205X01105010058 . Open Neurology Journal

Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters

Cardoso, S.; Carvalho, C.; Santos, R.; Correia, S.; Santos, M.S.; Seiça, R.; Oliveira, C.R.; Moreira, P.I., 2011. Synapse. 457 - 466. 6. 65. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953276927&partnerID=MN8TOARS . 10.1002/syn.20863 . Synapse

Epigenetics in neurodegeneration: A new layer of complexity

Marques, S.C.F.; Oliveira, C.R.; Pereira, C.M.F.; Outeiro, T.F., 2011. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 348 - 355. 2. 35. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952900959&partnerID=MN8TOARS . 10.1016/j.pnpbp.2010.08.008 . Progress in Neuro-Psychopharmacology and Biological Psychiatry

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1a Destabilization

Finley, L.; Carracedo, A.; Lee, J.; Souza, A.; Egia, A.; Zhang, J.; Teruya-Feldstein, J.; et al, 2011. Cancer Cell. 416 - 428. 3. 19. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952501323&partnerID=MN8TOARS . 10.1016/j.ccr.2011.02.014 . Cancer Cell

Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guided assay using lipopolysaccharide-stimulated macrophages

Francisco, Vera; Figueirinha, Artur; Neves, Bruno Miguel; García-Rodríguez, Carmen; Lopes, Maria Celeste; Cruz, Maria Teresa; Batista, Maria Teresa; et al, 2011. Journal of Ethnopharmacology. 818 - 827. 2. 133. 2011. http://hdl.handle.net/10316/18004 . 10.1016/j.jep.2010.11.018 . Journal of Ethnopharmacology

Amyloid-beta oligomers cause microtubule deregulation through NMDA receptors in mature hippocampal neurons

Mota, Sandra Isabel; Ferreira, Ildete Luisa; Resende de Oliveira, Catarina; Pereira, Cláudia; Rego, Ana Cristina Carvalho, 2011. Journal of Neurodegenerative Disorders. Supplement. 1. 2011. published Journal of Neurodegenerative Disorders

Injury markers in peripheral blood mononuclear cells from mild cognitive impairment and Alzheimer’s disease patients

Ferreira, Ildete Luisa; Mota, Sandra Isabel; Costa, Rui Miguel Oliveira da; Padovano, C; Fonseca, Ana Catarina Ribeiro da Graça; Letra, Liliana; Resende de Oliveira, Catarina; et al, 2011. Journal of Neurodegenerative Diseases. Supplement. 1. 2011. published Journal of Neurodegenerative Diseases

Mitochondria control NMDA receptor-dependent calcium rise evoked by amyloid-ß 1-42 oligomers in rat cortical neurons

Ferreiro, Elisabete; Ferreira, Ildete Luisa; Cardoso, Joao M.; Pereira, Cláudia; Resende de Oliveira, Catarina; Rego, Ana Cristina Carvalho, 2011. Alzheimer's & Dementia: Journal of Alzheimer's Association. 4. 7. 2011. published Alzheimer's & Dementia: Journal of Alzheimer's Association

Neurotensin downregulates the pro-inflammatory properties of skin dendritic cells and increases epidermal growth factor expression

da Silva, L.; Neves, B.M.; Moura, L.; Cruz, M.T.; Carvalho, E.; Neves, B. M.; Cruz, M. T., 2011. Biochimica et Biophysica Acta - Molecular Cell Research. 1863 - 1871. 10. 1813. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051782996&partnerID=MN8TOARS . 10.1016/j.bbamcr.2011.06.018 . Biochimica et Biophysica Acta - Molecular Cell Research

Signal transduction profile of chemical sensitisers in dendritic cells: An endpoint to be included in a cell-based in vitro alternative approach to hazard identification?

Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.; Cruz, M.T., 2011. Toxicology and Applied Pharmacology. 87 - 95. 2. 250. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650559757&partnerID=MN8TOARS . 10.1016/j.taap.2010.10.003 . Toxicology and Applied Pharmacology

Autophagy in Alzheimers disease

Moreira, P.I.; Santos, R.X.; Zhu, X.; Lee, H.-G.; Smith, M.A.; Casadesus, G.; Perry, G., 2010. Expert Review of Neurotherapeutics. 1209 - 1218. 7. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954196784&partnerID=MN8TOARS . 10.1586/ern.10.84 . Expert Review of Neurotherapeutics

Alzheimer's disease: Diverse aspects of mitochondrial malfunctioning

Santos, R.X.; Correia, S.C.; Wang, X.; Perry, G.; Smith, M.A.; Moreira, P.I.; Zhu, X., 2010. International Journal of Clinical and Experimental Pathology. 570 - 581. 6. 3. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956026971&partnerID=MN8TOARS . International Journal of Clinical and Experimental Pathology

Epigenetics and Neurodegeneration: A Connection Overlooked

Marques, Sueli C. F.; Pereira, Claudia M. F.; Outeiro, Tiago F., 2010. Epigenetics: Mechanism, Functions and Human Effects. 241 - 252. 2010. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000278550400010&KeyUID=WOS:000278550400010 . Epigenetics: Mechanism, Functions and Human Effects

Targeting autophagy in the brain: A promising approach?

Santos, R.X.; Cardoso, S.; Correia, S.; Carvalho, C.; Santos, M.S.; Moreira, P.I., 2010. Central Nervous System Agents in Medicinal Chemistry. 158 - 168. 2. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953681716&partnerID=MN8TOARS . Central Nervous System Agents in Medicinal Chemistry

Cholesterol and statins in Alzheimer's disease: Current controversies

Fonseca, A.C.R.G.; Resende, R.; Oliveira, C.R.; Pereira, C.M.F., 2010. Experimental Neurology. 282 - 293. 2. 223. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952583554&partnerID=MN8TOARS . 10.1016/j.expneurol.2009.09.013 . Experimental Neurology

Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing

Da Silva, L.; Carvalho, E.; Cruz, M.T., 2010. Expert Opinion on Biological Therapy. 1427 - 1439. 10. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956664657&partnerID=MN8TOARS . 10.1517/14712598.2010.515207 . Expert Opinion on Biological Therapy

Mitochondria: A therapeutic target in neurodegeneration

Moreira, P.I.; Zhu, X.; Wang, X.; Lee, H.-g.; Nunomura, A.; Petersen, R.B.; Perry, G.; Smith, M.A., 2010. Biochimica et Biophysica Acta - Molecular Basis of Disease. 212 - 220. 1. 1802. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-71849088759&partnerID=MN8TOARS . 10.1016/j.bbadis.2009.10.007 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.

Moreira, P.I.; Sayre, L.M.; Zhu, X.; Nunomura, A.; Smith, M.A.; Perry, G., 2010. Methods in molecular biology (Clifton, N.J.). 419 - 434. 610. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77449159407&partnerID=MN8TOARS . Methods in molecular biology (Clifton, N.J.)

Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease

Cardoso, S.M.; Pereira, C.F.; Moreira, P.I.; Arduino, D.M.; Esteves, A.R.; Oliveira, C.R., 2010. Experimental Neurology. 294 - 298. 2. 223. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952549554&partnerID=MN8TOARS . 10.1016/j.expneurol.2009.06.008 . Experimental Neurology

Essential oils from Distichoselinum tenuifolium: Chemical composition, cytotoxicity, antifungal and anti-inflammatory properties

Tavares, A.C.; Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Lopes, M.C.; Canhoto, J.; Salgueiro, L.R.; et al, 2010. Journal of Ethnopharmacology. 593 - 598. 3. 130. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954954559&partnerID=MN8TOARS . 10.1016/j.jep.2010.05.054 . Journal of Ethnopharmacology

Mitochondrial preconditioning: A potential neuroprotective strategy

Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, R.X.; Santos, M.S.; Oliveira, C.R.; Perry, G.; et al, 2010. Frontiers in Aging Neuroscience. AUG. 2. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955962818&partnerID=MN8TOARS . 10.3389/fnagi.2010.00138 . Frontiers in Aging Neuroscience

Chemical, antifungal and cytotoxic evaluation of the essential oil of Thymus zygis subsp. sylvestris

Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Lopes, M.C.; Salgueiro, L., 2010. Industrial Crops and Products. 70 - 75. 1. 32. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954864678&partnerID=MN8TOARS . 10.1016/j.indcrop.2010.03.005 . Industrial Crops and Products

Activation of phosphatidylinositol 3-kinase/akt and impairment of nuclear factor-¿B: Molecular mechanisms behind the arrested maturation/activation state of leishmania infantum-infected dendritic cells

Neves, B.M.; Silvestre, R.; Resende, M.; Ouaissi, A.; Cunha, J.; Tavares, J.; Loureiro, I.; et al, 2010. American Journal of Pathology. 2898 - 2911. 6. 177. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650195216&partnerID=MN8TOARS . 10.2353/ajpath.2010.100367 . American Journal of Pathology

Anti-inflammatory activity of cymbopogon citratus leaf infusion in lipopolysaccharide-stimulated dendritic cells: Contribution of the polyphenols

Figueirinha, A.; Cruz, M.T.; Francisco, V.; Lopes, M.C.; Batista, M.T., 2010. Journal of Medicinal Food. 681 - 690. 3. 13. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953730391&partnerID=MN8TOARS . 10.1089/jmf.2009.0115 . Journal of Medicinal Food

Effect of lipopolysaccharide, skin sensitizers and irritants on thioredoxin-1 expression in dendritic cells: Relevance of different signalling pathways

Francisco, V.; Neves, B.M.; Cruz, M.T.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2010. Archives of Dermatological Research. 271 - 282. 4. 302. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952180893&partnerID=MN8TOARS . 10.1007/s00403-009-0993-z . Archives of Dermatological Research

CXCL12/CXCR4 promotes motility and proliferation of glioma cells

do Carmo, Analia; Patricio, Ines; Cruz, Maria T.; Carvalheiro, Helena; Oliveira, Catarina R.; Lopes, Maria C.; do Carmo A; et al, 2010. Cancer Biology & Therapy. 56 - 65. 1. 9. 2010. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000274578800011&KeyUID=WOS:000274578800011 . 10.4161/cbt.9.1.10342 . Cancer Biology & Therapy

Effects of estrogen in the brain: Is it a neuroprotective agent in alzheimer's disease?

Correia, S.C.; Santos, R.X.; Cardoso, S.; Carvalho, C.; Santos, M.S.; Oliveira, C.R.; Moreira, P.I., 2010. Current Aging Science. 113 - 126. 2. 3. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953736213&partnerID=MN8TOARS . 10.2174/1874609811003020113 . Current Aging Science

Multiple Defects in Energy Metabolism in Alzheimer's Disease

Ferreira, I. L.; Resende, R.; Ferreiro, E.; Rego, A. C.; Pereira, C. F., 2010. Current Drug Targets. 1193 - 1206. 10. 11. 2010. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000285183900002&KeyUID=WOS:000285183900002 . Current Drug Targets

Alzheimer's disease: The quest to understand complexity

Marques, S.C.F.; Oliveira, C.R.; Outeiro, T.F.; Pereira, C.M.F., 2010. Journal of Alzheimer's Disease. 373 - 383. 2. 21. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957352488&partnerID=MN8TOARS . 10.3233/JAD-2010-100303 . Journal of Alzheimer's Disease

Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes

Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I., 2010. Current Neurovascular Research. 288 - 300. 4. 7. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650657043&partnerID=MN8TOARS . Current Neurovascular Research

Hypoxia-inducible factor 1: A new hope to counteract neurodegeneration?

Correia, S.C.; Moreira, P.I., 2010. Journal of Neurochemistry. 1 - 12. 1. 112. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-71649085107&partnerID=MN8TOARS . 10.1111/j.1471-4159.2009.06443.x . Journal of Neurochemistry

Alzheimer's Disease: An Overview

Moreira, P.I.; Zhu, X.; Smith, M.A.; Perry, G.; Castellani, R.J., 2010. Encyclopedia of Neuroscience. 259 - 263. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-84882903387&partnerID=MN8TOARS . 10.1016/B978-008045046-9.00544-1 . Encyclopedia of Neuroscience

Mitochondria: The missing link between preconditioning and neuroprotection

Correia, S.C.; Santos, R.X.; Perry, G.; Zhu, X.; Moreira, P.I.; Smith, M.A., 2010. Journal of Alzheimer's Disease. SUPPL.2. 20. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956220265&partnerID=MN8TOARS . 10.3233/JAD-2010-100669 . Journal of Alzheimer's Disease

Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia

Cardoso, S.; Santos, M.S.; Seiça, R.; Moreira, P.I., 2010. Biochimica et Biophysica Acta - Molecular Basis of Disease. 942 - 951. 11. 1802. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956710094&partnerID=MN8TOARS . 10.1016/j.bbadis.2010.07.001 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Potential antioxidant and anti-inflammatory properties in Teucrium salviastrum Schreb

Cabral, C.; Francisco, V; Cruz, M.; Lopes, M.; Salgueiro, L.; Sales, F.; Batista, M., 2010. Planta Medica. 2010. https://publons.com/publon/7273471/ . 10.1055/S-0030-1264535 . Planta Medica

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

Moreira, P.I.; Carvalho, C.; Zhu, X.; Smith, M.A.; Perry, G., 2010. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2 - 10. 1. 1802. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-71749121998&partnerID=MN8TOARS . 10.1016/j.bbadis.2009.10.006 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Polyphenols from Cymbopogon citratus inhibit iNOS expression and NO production - a promising source of new anti-inflammatory drugs

Francisco, V; Figueirinha, A.; Neves, B.; Garcia-Rodriguez, C.; Lopes, M.; Cruz, M.; Batista, M., 2010. Planta Medica. 2010. https://publons.com/publon/21604165/ . Planta Medica

Mitochondrial dysfunction and oxidative stress in Alzheimer's disease

Moreira, P.I., 2010. European Neurological Review. 17 - 21. 1. 5. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858166678&partnerID=MN8TOARS . European Neurological Review

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease

Santos, R.X.; Correia, S.C.; Wang, X.; Perry, G.; Smith, M.A.; Moreira, P.I.; Zhu, X., 2010. Journal of Alzheimer's Disease. SUPPL.2. 20. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956199031&partnerID=MN8TOARS . 10.3233/JAD-2010-100666 . Journal of Alzheimer's Disease

ROLE OF GLYCOGEN SYNTHASE KINASE-3B ON TAU PHOSPHORYLATION IN ALZHEIMER'S DISEASE

Resende, Rosa; Oliveira, Catarina Resende; Pereira, Claudia M. F., 2010. Advances in Medicine and Biology, Vol 2. 197 - 210. 2. 2010. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000278696200007&KeyUID=WOS:000278696200007 . Advances in Medicine and Biology, Vol 2

ER stress-mediated apoptotic pathway induced by aß peptide requires the presence of functional mitochondria

Costa, R.O.; Ferreiro, E.; Cardoso, S.M.; Oliveira, C.R.; Pereira, C.M.F., 2010. Journal of Alzheimer's Disease. 625 - 636. 2. 20. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954516455&partnerID=MN8TOARS . 10.3233/JAD-2010-091369 . Journal of Alzheimer's Disease

Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia

Carvalho, C.; Correia, S.C.; Santos, R.X.; Cardoso, S.; Moreira, P.I.; Clark, T.A.; Zhu, X.; Smith, M.A.; Perry, G., 2009. Journal of Bioenergetics and Biomembranes. 433 - 440. 5. 41. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449397210&partnerID=MN8TOARS . 10.1007/s10863-009-9247-1 . Journal of Bioenergetics and Biomembranes

Differential roles of PI3-Kinase, MAPKs and NF-¿B on the manipulation of dendritic cell T<inf>h</inf>1/T<inf>h</inf>2 cytokine/chemokine polarizing profile

Neves, B.M.; Cruz, M.T.; Francisco, V.; Garcia-Rodriguez, C.; Silvestre, R.; Cordeiro-da-Silva, A.; Dinis, A.M.; et al, 2009. Molecular Immunology. 2481 - 2492. 13. 46. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650397827&partnerID=MN8TOARS . 10.1016/j.molimm.2009.05.021 . Molecular Immunology

Neuroprotective effects of statins in an in vitro model of alzheimer's disease

Fonseca, A.C.R.G.; Proena, T.; Resende, R.; Oliveira, C.R.; Pereira, C.M.F., 2009. Journal of Alzheimer's Disease. 503 - 517. 3. 17. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67849099662&partnerID=MN8TOARS . 10.3233/JAD-2009-1067 . Journal of Alzheimer's Disease

Food deprivation promotes oxidative imbalance in rat brain

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Communication between endoplamic reticulum and mitochondria in the neuronal death induced by amyloid-beta peptide

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An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

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RNA oxidation in Alzheimer disease and related neurodegenerative disorders

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CXCL12/CXCR4 MODULATES GLIOMA CELL SURVIVAL AND MOTILITY

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Mitochondria as a therapeutic target in Alzheimer's disease and diabetes

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Doxorubicin: The good, the bad and the ugly effect

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Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage

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Metformin promotes isolated rat liver mitochondria impairment

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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Alzheimer disease and the role of free radicals in the pathogenesis of the disease

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Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death

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Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease

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Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes

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Nucleic acid oxidation in Alzheimer disease

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Amyloid-ß overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

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Antioxidant therapy in Alzheimer's disease: theory and practice.

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Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview.

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Essential oil of Daucus carota subsp. halophilus: Composition, antifungal activity and cytotoxicity

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Sublethal RNA oxidation as a mechanism for neurodegenerative disease

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Susceptibility of hippocampal neurons to Aß peptide toxicity is associated with perturbation of Ca2+ homeostasis

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Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells

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Neurodegeneration in Alzheimer's disease: Inter-organelle cross-talk and oxidative stress in cell life and death decisions

Ferreiro, Elisabete; Resende, Rosa; Costa, Rui Miguel Oliveira da; Moreira, Paula Isabel; Morais Cardoso, Sandra; Pereira, Cláudia; Resende de Oliveira, Catarina; et al, 2007. Free Radical Research. S11 - S11. 41. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300021&KeyUID=WOS:000252296300021 . Free Radical Research

Does mitochondria impairment affect endoplasmic reticulum function during amyloid-beta toxicity?

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Indices of metabolic dysfunction and oxidative stress

Casadesus, G.; Moreira, P.I.; Nunomura, A.; Siedlak, S.L.; Bligh-Glover, W.; Balraj, E.; Petot, G.; Smith, M.A.; Perry, G., 2007. Neurochemical Research. 717 - 722. 4-5. 32. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947593456&partnerID=MN8TOARS . 10.1007/s11064-007-9296-y . Neurochemical Research

Prevention and treatment of Alzheimer disease and aging: Antioxidants

Liu, Q.; Xie, F.; Rolston, R.; Moreira, P.I.; Nunomura, A.; Zhu, X.; Smith, M.A.; Perry, G., 2007. Mini-Reviews in Medicinal Chemistry. 171 - 180. 2. 7. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33847776693&partnerID=MN8TOARS . 10.2174/138955707779802552 . Mini-Reviews in Medicinal Chemistry

Neuropathology and treatment of Alzheimer disease: Did we lose the forest for the trees?

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Neurodegeneration in Alzheimer's disease: Inter-organelle cross-talk and oxidative stress in cell life and death decisions

Ferreiro, Elisabete; Resende, Rosa; Costa, Rui Miguel Oliveira da; Moreira, Paula Isabel; Morais Cardoso, Sandra; Pereira, Cláudia; Resende de Oliveira, Catarina; et al, 2007. Free Radical Research. S11 - S11. 41. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300021&KeyUID=WOS:000252296300021 . Free Radical Research

Vascular oxidative stress in Alzheimer disease

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Autophagocytosis of mitochondria is prominent in Alzheimer disease

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Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats

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Alzheimer's disease: A lesson from mitochondrial dysfunction

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Effect of skin sensitizers on inducible nitric oxide synthase expression and nitric oxide production in skin dendritic cells: Role of different immunosuppressive drugs

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The key role of oxidative stress in alzheimer's disease

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Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts

Moreira, P.I.; Harris, P.L.R.; Zhu, X.; Santos, M.S.; Oliveira, C.R.; Smith, M.A.; Perry, G., 2007. Journal of Alzheimer's Disease. 195 - 206. 2. 12. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34848890388&partnerID=MN8TOARS . Journal of Alzheimer's Disease

Erratum: Increased autophagic degradation of mitochondria in Alzheimer disease (Autophagy)

Moreira, P.I.; Siedlak, S.L.; Wang, X.; Santos, M.S.; Oliveira, C.R.; Tabaton, M.; Nunomura, A.; et al, 2007. Autophagy. 614 - 615. 6. 3. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35848931249&partnerID=MN8TOARS . Autophagy

Oxidative RNA damage and neurodegeneration

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Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

Nunomura, A.; Moreira, P.I.; Lee, H.G.; Zhu, X.; Castellani, R.J.; Smith, M.A.; Perry, G., 2007. CNS and Neurological Disorders - Drug Targets. 411 - 423. 6. 6. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-41749088686&partnerID=MN8TOARS . 10.2174/187152707783399201 . CNS and Neurological Disorders - Drug Targets

Erratum: Autophagocytosis of mitochondria is prominent in Alzheimer disease (Journal of Neuropathology and Experimental Neurology (2007) 66, (525-532))

Moreira, P.I.; Siedlak, S.L.; Wang, X.; Santos, M.S.; Oliveira, C.R.; Tabaton, M.; Nunomura, A.; et al, 2007. Journal of Neuropathology and Experimental Neurology. 7. 66. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34447321588&partnerID=MN8TOARS . 10.1097/01.jnen.0000263876.99435.cb . Journal of Neuropathology and Experimental Neurology

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes

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Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets

Nunes, E.; Peixoto, F.; Louro, T.; Sena, C.M.; Santos, M.S.; Matafome, P.; Moreira, P.I.; Seiça, R., 2007. Acta Diabetologica. 121 - 130. 3. 44. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548177719&partnerID=MN8TOARS . 10.1007/s00592-007-0252-8 . Acta Diabetologica

Iron: The redox-active center of oxidative stress in Alzheimer disease

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Differential CXCR4 expression induced by skin sensitizers or irritants in dendritic cell models

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Compensatory responses induced by oxidative stress in Alzheimer disease

Moreira, P.I.; Zhu, X.; Liu, Q.; Honda, K.; Siedlak, S.L.; Harris, P.L.; Smith, M.A.; Perry, G., 2006. Biological Research. 7 - 13. 1. 39. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745840777&partnerID=MN8TOARS . Biological Research

Telomeres and telomerase in Alzheimer's disease: Epiphenomena or a new focus for therapeutic strategy?

Franco, S.; Blasco, M.A.; Siedlak, S.L.; Harris, P.L.R.; Moreira, P.I.; Perry, G.; Smith, M.A., 2006. Alzheimer's and Dementia. 164 - 168. 3. 2. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744931650&partnerID=MN8TOARS . 10.1016/j.jalz.2006.03.001 . Alzheimer's and Dementia

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease

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Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.

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The key role of mitochondria in Alzheimer's disease

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Therapeutic options in Alzheimer's disease

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Foreword: Mitochondria in Alzheimer disease

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In vitro study of Amyloid-ß peptide toxicity. The role of physical state.

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Insulin attenuates diabetes-related mitochondrial alterations: A comparative study

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Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure

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Presenilin mutation: A deadly first hit in Alzheimer disease - A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice"

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Involvement of oxidative stress in Alzheimer disease

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An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity

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Brain and brawn: Parallels in oxidative strength

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Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease

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Redox metals and oxidative abnormalities in human prion diseases

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Oxidative stress mechanisms and potential therapeutics in Alzheimer disease

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Therapeutic opportunities in Alzheimer Disease: One for all or all for one?

Marlatt, M.W.; Webber, K.M.; Moreira, P.I.; Lee, H.-G.; Casadesus, G.; Honda, K.; Zhu, X.; Perry, G.; Smith, M.A., 2005. Current Medicinal Chemistry. 1137 - 1147. 10. 12. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18544380930&partnerID=MN8TOARS . 10.2174/0929867053764644 . Current Medicinal Chemistry

CoQ10 therapy attenuates amyloid ß-peptide toxicity in brain mitochondria isolated from aged diabetic rats

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Aeroallergens sensitization in an allergic paediatric population of Cova da Beira, Portugal.

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Redox active iron at the center of oxidative stress in Alzheimer disease

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Neurodegenerative pathways in Parkinson's disease: Therapeutic strategies

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Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies

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Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

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Oxidative stress: The old enemy in Alzheimer's disease pathophysiology

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Tau phosphorylation in Alzheimer's disease: Pathogen or protector?

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Mitogen- and stress-activated protein kinase 1: Convergence of the ERK and p38 pathways in Alzheimer's disease

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Chronological primacy of oxidative stress in Alzheimer disease

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The sensitizers nickel sulfate and 2,4-dinitrofluorobenzene increase CD40 and IL-12 receptor expression in a fetal skin dendritic cell line

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Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line

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Mechanism of amyloid-beta induced early synaptotoxicity.

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Metal ions and oxidative protein modification in neurological disease

Sayre, L.M.; Moreira, P.I.; Smith, M.A.; Perry, G., 2005. Annali dell'Istituto Superiore di Sanita. 143 - 164. 2. 41. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-31644435822&partnerID=MN8TOARS . Annali dell'Istituto Superiore di Sanita

A second look into the oxidant mechanisms in Alzheimer's disease

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Protective effect of zinc on amyloid-ß 25-35 and 1-40 mediated toxicity

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Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies

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The crosstalk between the endoplasmic reticulum and mitochondria in Alzheimer's disease

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Oxidative stress and neurodegeneration

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Endoplasmic reticulum dysfunction and oxidative stress induced by the prion peptide

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Alzheimer's disease: An intracellular movement disorder?

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Neurodegenerative pathways in Parkinson's disease: Therapeutic strategies

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Insulin protects against amyloid ß-peptide toxicity in brain mitochondria of diabetic rats

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Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen

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Alzheimer's disease and oxidative stress: The old problem remains unsolved

Moreira, P.I.; Honda, K.; Liu, Q.; Aliev, G.; Oliveira, C.R.; Santos, M.S.; Zhu, X.; Smith, M.A.; Perry, G., 2005. Current Medicinal Chemistry - Central Nervous System Agents. 51 - 62. 1. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-15344351142&partnerID=MN8TOARS . Current Medicinal Chemistry - Central Nervous System Agents

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

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Oxidative damage and Alzheimer's disease: Are antioxidant therapies useful?

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Therapeutic potential of oxidant mechanisms in Alzheimer's disease

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Staying connected: Synapses in alzheimer disease

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The Sensitizers Nickel Sulfate and 2,4-dinitrofluorobenzene Increase CD40 and IL-12 Receptor Expression in a Fetal Skin Dendritic Cell Line

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Hydroxytamoxifen protects against oxidative stress in brain mitochondria

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Contact sensitizer nickel sulfate activates the transcription factors NF-kB and AP-1 and increases the expression of nitric oxide synthase in a skin dendritic cell line

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Effect of streptozotocin-induced diabetes on rat brain mitochondria

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Neurofilament proteins in neurodegenerative diseases

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The sensitizer 2,4-dinitrofluorobenzene activates caspase-3 and induces cell death in a skin dendritic cell line

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Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-¿B activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

Vital, A.L.; Gonçalo, M.; Cruz, M.T.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2003. Mediators of Inflammation. 71 - 78. 2. 12. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038466135&partnerID=MN8TOARS . 10.1080/0962935031000097673 . Mediators of Inflammation

Neuroprotection strategies: Effect of vinpocetinein in vitro oxidative stress models | Estratégias de neuroprotecção: Efeito da vimpocetina em modelos in vitro de stresse oxidativo

Pereira, C.; Agostinho, P.; Moreira, P.I.; Duarte, A.I.; Santos, M.S.; Oliveira, C.R., 2003. Acta Medica Portuguesa. 401 - 406. 6. 16. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-9644310235&partnerID=MN8TOARS . Acta Medica Portuguesa

The Sensitizer 2,4-Dinitrofluorobenzene Activates Caspase-3 and Induces Cell Death in a Skin Dendritic Cell Line

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Figueiredo, Américo; Carvalho, Arsélio P.; Lopes, Maria Celeste, 2003. 2003. http://hdl.handle.net/10316/11811 .

Increased vulnerability of brain mitochondria in diabetic (goto-kakizaki) rats with aging and amyloid-ß exposure

Moreira, P.I.; Santos, M.S.; Moreno, A.M.; Seiça, R.; Oliveira, C.R., 2003. Diabetes. 1449 - 1456. 6. 52. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038321341&partnerID=MN8TOARS . 10.2337/diabetes.52.6.1449 . Diabetes

Neuroprotection strategies: Effect of vinpocetinein in vitro oxidative stress models | Estratégias de neuroprotecção: Efeito da vimpocetina em modelos in vitro de stresse oxidativo

Pereira, C.; Agostinho, P.; Moreira, P.I.; Duarte, A.I.; Santos, M.S.; Oliveira, C.R., 2003. Acta Medica Portuguesa. 401 - 406. 6. 16. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-9644310235&partnerID=MN8TOARS . Acta Medica Portuguesa

[Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models].

Pereira, Claudia; Agostinho, Paula; Moreira, Paula I; Duarte, Ana I; Santos, Maria S; Oliveira, Catarina R, 2003. Acta medica portuguesa. 401 - 6. 6. 16. 2003. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:15631851&KeyUID=MEDLINE:15631851 . Acta medica portuguesa

Effect of amyloid ß-peptide on permeability transition pore: A comparative study

Moreira, P.I.; Santos, M.S.; Moreno, A.; Rego, A.C.; Oliveira, C., 2002. Journal of Neuroscience Research. 257 - 267. 2. 69. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037100213&partnerID=MN8TOARS . 10.1002/jnr.10282 . Journal of Neuroscience Research

Differential activation of nuclear factor kappa B subunits in a skin dendritic cell line in response to the strong sensitizer 2,4-dinitrofluorobenzene.

Cruz MT; Duarte CB; Gonçalo M; Figueiredo A; Carvalho AP; Lopes MC; Cruz, M. T.; et al, 2002. Archives of Dermatological Research. 419 - 425. 9. 294. 2002. http://europepmc.org/abstract/med/12522580 . 10.1007/s00403-002-0342-y . Archives of Dermatological Research

Amyloid ß-peptide promotes permeability transition pore in brain mitochondria

Moreira, P.I.; Santos, M.S.; Moreno, A.; Oliveira, C., 2001. Bioscience Reports. 789 - 800. 6. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035780141&partnerID=MN8TOARS . 10.1023/A:1015536808304 . Bioscience Reports

Granulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line

Cruz, M.T.; Duarte, C.B.; Gonçalo, M.; Figueiredo, A.; Carvalho, A.P.; Lopes, M.C., 2001. Immunology and Cell Biology. 590 - 596. 6. 79. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035176476&partnerID=MN8TOARS . 10.1046/j.1440-1711.2001.01041.x . Immunology and Cell Biology

LPS induction of I¿B-a degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, tyrphostin B42

Cruz, M.T.; Duarte, C.B.; Gonçalo, M.; Carvalho, A.P.; Lopes, M.C., 2001. Nitric Oxide - Biology and Chemistry. 53 - 61. 1. 5. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035708551&partnerID=MN8TOARS . 10.1006/niox.2000.0320 . Nitric Oxide - Biology and Chemistry

Effect of Zinc Ions on the Cytotoxicity Induced by the Amyloid beta-Peptide

Moreira, Paula; Pereira, Claudia; Santos, Maria S.; Oliveira, Catarina, 2000. Antioxidants & Redox Signaling. 317 - 325. 2. 2. 2000. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000207500700014&KeyUID=WOS:000207500700014 . 10.1089/ars.2000.2.2-317 . Antioxidants & Redox Signaling

Synaptosomal response to oxidative stress: Effect of vinpocetine

Santos, M.S.; Duarte, A.I.; Moreira, P.I.; Oliveira, C.R., 2000. Free Radical Research. 57 - 66. 1. 32. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033988559&partnerID=MN8TOARS . Free Radical Research

Effect of Zinc Ions on the Cytotoxicity Induced by the Amyloid beta-Peptide

Moreira, Paula; Pereira, Claudia; Santos, Maria S.; Oliveira, Catarina, 2000. Antioxidants & Redox Signaling. 317 - 325. 2. 2. 2000. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000207500700014&KeyUID=WOS:000207500700014 . 10.1089/ars.2000.2.2-317 . Antioxidants & Redox Signaling

Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis

Pereira, CF; de Oliveira, CR, 2000. Neuroscience Research. 227 - 236. 3. 37. 2000. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000088427400008&KeyUID=WOS:000088427400008 . 10.1016/S0168-0102(00)00124-3 . Neuroscience Research

Effect of zinc ions on the cytotoxicity induced by the amyloid ß- peptide

Moreira, P.; Pereira, C.; Santos, M.S.; Oliveira, C., 2000. Antioxidants and Redox Signaling. 317 - 325. 2. 2. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033949740&partnerID=MN8TOARS . Antioxidants and Redox Signaling

Vinpocetine attenuates the metabolic dysfunction induced by amyloid beta-peptides in PC12 cells

Pereira, C; Agostinho, P; Oliveira, CR; Pereira, C.; Agostinho, P.; Oliveira, C.R., 2000. Free Radical Research. 497 - 506. 5. 33. 2000. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000166441800006&KeyUID=WOS:000166441800006 . 10.1080/10715760000301041 . Free Radical Research

Effect of zinc ions on the cytotoxicity induced by the amyloid ß- peptide

Moreira, P.; Pereira, C.; Santos, M.S.; Oliveira, C., 2000. Antioxidants and Redox Signaling. 317 - 325. 2. 2. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033949740&partnerID=MN8TOARS . Antioxidants and Redox Signaling

Susceptibility to ß-amyloid-induced toxicity is decreased in Goto- Kakizaki diabetic rats: Involvement of oxidative stress

Pereira, C.; Moreira, P.; Seiça, R.; Santos, M.S.; Oliveira, C.R., 2000. Experimental Neurology. 383 - 391. 1. 161. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034051172&partnerID=MN8TOARS . 10.1006/exnr.1999.7270 . Experimental Neurology

Susceptibility to ß-amyloid-induced toxicity is decreased in Goto- Kakizaki diabetic rats: Involvement of oxidative stress

Pereira, C.; Moreira, P.; Seiça, R.; Santos, M.S.; Oliveira, C.R., 2000. Experimental Neurology. 383 - 391. 1. 161. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034051172&partnerID=MN8TOARS . 10.1006/exnr.1999.7270 . Experimental Neurology

Involvement of oxidative stress on the impairment of energy metabolism induced by Aß peptides on PC12 cells: Protection by antioxidants

Pereira, C.; Santos, M.S.; Oliveira, C., 1999. Neurobiology of Disease. 209 - 219. 3. 6. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033022771&partnerID=MN8TOARS . 10.1006/nbdi.1999.0241 . Neurobiology of Disease

Mitochondrial function is differentially affected upon oxidative stress

Cardoso, S.M.; Pereira, C.; Oliveira, C.R., 1999. Free Radical Biology and Medicine. 3 - 13. 1-2. 26. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345222531&partnerID=MN8TOARS . 10.1016/S0891-5849(98)00205-6 . Free Radical Biology and Medicine

Involvement of JAK2 and MAPK on type II nitric oxide synthase expression in skin-derived dendritic cells

Cruz, M.T.; Duarte, C.B.; Gonçalo, M.; Carvalho, A.P.; Lopes, M.G.; Cruz, M. T.; Duarte, C. B.; et al, 1999. American Journal of Physiology - Cell Physiology. C1050 - C1057. 6 46-6. 277. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033373205&partnerID=MN8TOARS . 10.1152/AJPCELL.1999.277.6.C1050 . American Journal of Physiology - Cell Physiology

Photosensitization of lymphoblastoid cells with phthalocyanines at different saturating incubation times

Gomes, E. R.; Cruz, T.; Lopes, C. F.; Carvalho, A. P.; Duarte, C. B.; Gomes, E.R.; Lopes, C.F.; Carvalho, A.P.; Duarte, C.B., 1999. Cell Biology and Toxicology. 249 - 260. 4. 15. 1999. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000084642800005&KeyUID=WOS:000084642800005 . 10.1023/a:1007615813184 . Cell Biology and Toxicology

Calcium-dependent nitric oxide synthase activity in rat thymocytes

Cruz, M.T.; Carmo, A.; Carvalho, A.P.; Lopes, M.C., 1998. Biochemical and Biophysical Research Communications. 98 - 103. 1. 248. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032499870&partnerID=MN8TOARS . 10.1006/bbrc.1998.8865 . Biochemical and Biophysical Research Communications

The protective effect of vitamin E, idebenone and reduced glutathione on free radical mediated injury in rat brain synaptosomes

Cardoso, S.M.; Pereira, C.; Oliveira, C.R., 1998. Biochemical and Biophysical Research Communications. 703 - 710. 3. 246. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032577242&partnerID=MN8TOARS . 10.1006/bbrc.1998.8563 . Biochemical and Biophysical Research Communications

Mitochondrial function impairment induced by amyloid beta-peptide on PC12 cells

Pereira, C; Santos, MS; Oliveira, C; Pereira, C.; Santos, M.S.; Oliveira, C., 1998. Neuroreport. 1749 - 1755. 8. 9. 1998. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000074198700015&KeyUID=WOS:000074198700015 . 10.1097/00001756-199806010-00015 . Neuroreport

Metabolic inhibition increases glutamate susceptibility on a PC12 cell line

Pereira, C; Santos, MS; Oliveira, C; Pereira, C.; Santos, M.S.; Oliveira, C., 1998. Journal of Neuroscience Research. 360 - 370. 3. 51. 1998. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000071805700009&KeyUID=WOS:000071805700009 . 10.1002/(SICI)1097-4547(19980201)51:3<360::AID-JNR9>3.3.CO;2-7 . Journal of Neuroscience Research

Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress

Pereira, C.M.F.; Oliveira, C.R., 1997. Free Radical Biology and Medicine. 637 - 647. 4. 23. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030757990&partnerID=MN8TOARS . 10.1016/S0891-5849(97)00020-8 . Free Radical Biology and Medicine

Interaction between polyalkylcyanoacrylate nanoparticles and peritoneal macrophages: MTT metabolism, NBT reduction, and NO production

Cruz, T.; Gaspar, R.; Donato, A.; Lopes, C., 1997. Pharmaceutical Research. 73 - 79. 1. 14. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031042535&partnerID=MN8TOARS . 10.1023/A:1012059501947 . Pharmaceutical Research

Contribution of plasma membrane and endoplasmic reticulum Ca2+-ATPases to the synaptosomal [Ca2+]i increase during oxidative stress

Pereira, C.; Ferreira, C.; Carvalho, C.; Oliveira, C., 1996. Brain Research. 269 - 277. 1-2. 713. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029928472&partnerID=MN8TOARS . 10.1016/0006-8993(95)01554-X . Brain Research

Effect of lipid peroxidation on [Ca2+]i of rat synaptosomes

Pereira, Cláudia; Resende de Oliveira, Catarina, 1993. Journal of Neurochemistry. S151D - S151D. supplement. 1993. published Journal of Neurochemistry

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