Pedro R. Figueiredo

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Pedro R. Figueiredo has a Master in Medicinal Chemistry and a Bachelor in Chemistry, both by UMinho. He is currently a PhD student at the UCoimbra developing the project "Enzymatic Synthesis of Biodegradable Amphiphilic Polymer-drugs for Cancer Treatment" at the Rational Protein Engineering group in collaboration with CICECO - Aveiro Institute of Materials.


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Information about journal articles, updated at 28-05-2023, from platform CIÊNCIAVITAE.

Insights into the Degradation of Polymer-Drug Conjugates by an Overexpressed Enzyme in Cancer Cells

Pedro R. Figueiredo; González, Ricardo D.; Carvalho, Alexandra T. P., Journal of Medicinal Chemistry. 2761 - 2772. 4. 66. 2023. . 10.1021/acs.jmedchem.2c01781 . Journal of Medicinal Chemistry

Cell delivery peptides for small interfering RNAs targeting SARS-CoV-2 new variants through a bioinformatics and deep learning design

Ricardo D. González; Pedro R. Figueiredo; Alexandra T.P. Carvalho, BioRxiv. 2022. published BioRxiv

Effects of Cap-domain Carboxylesterase Mutations on Polyester Synthesis

Pedro R. Figueiredo; Beatriz C. Almeida; Daniel F.A.R. Dourado; Stephanie Paul; Derek Quinn; Thomas S. Moody; Andreia F. Sousa; Armando J.D. Silvestre; Alexandra T.P. Carvalho, Polymers. 2022. submitted Polymers

Antidotal effect of cyclosporine A against a-amanitin toxicity in CD-1 mice, at clinical relevant doses

Garcia, Juliana; Carvalho, Alexandra; Neves, Ricardo Pires; Malheiro, Rui; Rodrigues, Daniela F.; Pedro R. Figueiredo; Bovolini, Antonio; et al, Food and Chemical Toxicology. 2022. 10.1016/j.fct.2022.113198 . published Food and Chemical Toxicology

An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration - prepared from a known folate receptor ligand

Carlos B. P. Oliveira; Sérgio R. S. Veloso; Pedro R. Figueiredo; Alexandra T. P. Carvalho; Loic Hilliou; Pereira, Renato B.; David M. Pereira; et al, Soft Matter. 2022. 10.1039/D2SM00121G . accepted Soft Matter

Development of Enzymatic Variants for the Synthesis of Bioresorbable Polyesters

Beatriz C. Almeida; Pedro R. Figueiredo; Daniel F.A.R. Dourado; Stephanie Paul; Derek Quinn; Thomas S. Moody; Andreia F. Sousa; Armando J.D. Silvestre; Alexandra T. P. Carvalho, Organic Process Research & Development. 2022. . published Organic Process Research & Development

Human Carboxylesterase 2 in Cocaine Metabolism

Pedro R. Figueiredo; Ricardo D. González; Alexandra T. P. Carvalho, Molecular Catalysis. 2021. 10.1016/j.mcat.2021.111938 . published Molecular Catalysis

Introduction of a Glycine Linker Connecting the Heavy and Light Chains in Synthetic Cardosin B-Derived Rennet Changes the Specificity of Subpocket S3'

Pedro R. Figueiredo; Sónia F.G. Santos; Beatriz C. Almeida; Isaura Simões; Alexandra T.P. Carvalho, Journal of Physical Chemistry B. 2021. 10.1021/acs.jpcb.1c01826 . published Journal of Physical Chemistry B

Transcription factor allosteric regulation through substrate coordination to zinc

Beatriz C. Almeida; Jennifer Kaczmarek; Pedro R. Figueiredo; Kristala L. Jones Prather; Alexandra T.P. Carvalho, NAR Genomics and Bioinformatics. 2021. 10.1093/nargab/lqab033 . published NAR Genomics and Bioinformatics

Enzymatic Synthesis of Polyesters: a QM/MM study

Pedro R. Figueiredo; Beatriz C. Almeida; Daniel F.A.R. Dourado; Andreia F. Sousa; Armando J.D. Silvestre; Alexandra T.P. Carvalho, ChemCatChem. 2020. 10.1002/cctc.202000780 . ChemCatChem

Enzymatic Polymerization of PCL-PEG Co-polymers for Biomedical Applications

Pedro Figueiredo; Beatriz C. Almeida; Alexandra T. P. Carvalho,, Frontiers in Molecular Biosciences. 109. 6. 2019. 10.3389/fmolb.2019.00109 . published Frontiers in Molecular Biosciences

PCL enzymatic hydrolysis: a mechanistic study

Beatriz C. Almeida; Pedro Figueiredo; Alexandra T.P. Carvalho, ACS Omega. 2019. 10.1021/acsomega.9b00345 . published ACS Omega

Adenine Derivatives: Promising Candidates for Breast Cancer Treatment

Pedro Figueiredo; Marta Costa; Olívia Pontes; Fátima Baltazar; Fernanda Proença, European Journal of Organic Chemistry. 3943 - 3956. 29. 2018. 2018. 10.1002/ejoc.201800629 . published European Journal of Organic Chemistry

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