Aji Alex Moothedathu Raynold

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Publications

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Information about journal articles, updated at 18-04-2024, from platform CIÊNCIAVITAE.

Roadmap on nanomedicine for the central nervous system

Ciofani, Gianni; Campisi, Marco; Mattu, Clara; Kamm, Roger D; Chiono, Valeria; Raynold, Aji Alex Moothedathu; Freitas, João S; et al, Journal of Physics: Materials. 2. 6. 2023. http://dx.doi.org/10.1088/2515-7639/acab88 . 10.1088/2515-7639/acab88 . Journal of Physics: Materials

Six-month effective treatment of corneal graft rejection

Tuo Meng; Jinhua Zheng; Min Chen; Yang Zhao; Hadi Sudarjat; Aji Alex M.R.; Vineet Kulkarni; et al, Science Advances. 12. 9. 2023. http://dx.doi.org/10.1126/sciadv.adf4608 . 10.1126/sciadv.adf4608 . Science Advances

LC-MS/MS method for simultaneous quantification of dexamethasone and tobramycin in rabbit ocular biofluids

Journal of Chromatography B. 122610 - 122610. 1170. 2021. http://dx.doi.org/10.1016/j.jchromb.2021.122610 . 10.1016/j.jchromb.2021.122610 . Journal of Chromatography B

3D engineering for optic neuropathy treatment

Drug Discovery Today. 181 - 188. 1. 26. 2021. http://dx.doi.org/10.1016/j.drudis.2020.09.034 . 10.1016/j.drudis.2020.09.034 . Drug Discovery Today

Competitive binding and molecular crowding regulate the cytoplasmic interactome of non-viral polymeric gene delivery vectors

Moothedathu Raynold, Aji Alex; Li, Danyang; Chang, Lan; Gautrot, Julien E., Nature Communications. 1. 12. 2021. http://dx.doi.org/10.1038/s41467-021-26695-w . 10.1038/s41467-021-26695-w . Nature Communications

Comparative Assessment of Active Targeted Redox Sensitive Polymersomes Based on pPEGMA-S-S-PLA Diblock Copolymer with Marketed Nanoformulation

Raynold, Aji, Biomacromolecules. 2549 - 2566. 7. 19. 2018. https://doi.org/10.1021/acs.biomac.8b00178 . 10.1021/acs.biomac.8b00178 . Biomacromolecules

ATRP fabricated and short chain polyethyleneimine grafted redox sensitive polymeric nanoparticles for co-delivery of anticancer drug and siRNA in cancer therapy

Chetan Nehate; Aji Alex Moothedathu Raynold; Veena Koul, ACS Applied Materials & Interfaces. 2017. https://doi.org/10.1021%2Facsami.7b11716 . 10.1021/acsami.7b11716 . ACS Applied Materials & Interfaces

Self assembled dual responsive micelles stabilized with protein for co-delivery of drug and siRNA in cancer therapy

M.R. Aji Alex; Chetan Nehate; Srivani Veeranarayanan; D. Sakthi Kumar; Ritu Kulshreshtha; Veena Koul, Biomaterials. 94 - 106. 133. 2017. https://doi.org/10.1016%2Fj.biomaterials.2017.04.022 . 10.1016/j.biomaterials.2017.04.022 . Biomaterials

Combinatorial delivery of superparamagnetic iron oxide nanoparticles (¿Fe 2 O 3 ) and doxorubicin using folate conjugated redox sensitive multiblock polymeric nanocarriers for enhancing the chemotherapeutic efficacy in cancer cells

Chetan Nehate; M.R. Aji Alex; Arun Kumar; Veena Koul, Materials Science and Engineering: C. 1128 - 1143. 75. 2017. https://doi.org/10.1016/j.msec.2017.03.024 . 10.1016/j.msec.2017.03.024 . Materials Science and Engineering: C

Folic acid and trastuzumab conjugated redox responsive random multiblock copolymeric nanocarriers for breast cancer therapy: In-vitro and in-vivo studies

Arun Kumar; Shantanu V. Lale; M.R. Aji Alex; Veena Choudhary; Veena Koul, Colloids and Surfaces B: Biointerfaces. 369 - 378. 149. 2017. https://doi.org/10.1016%2Fj.colsurfb.2016.10.044 . 10.1016/j.colsurfb.2016.10.044 . Colloids and Surfaces B: Biointerfaces

Eugenol nanocapsule for enhanced therapeutic activity against periodontal infections

Pramod, K.; Aji Alex, M.R.; Singh, M.; Dang, S.; Ansari, S.H.; Ali, J., Journal of Drug Targeting. 24 - 33. 1. 24. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955115014&partnerID=MN8TOARS . 10.3109/1061186X.2015.1052071 . Journal of Drug Targeting

Click modified amphiphilic graft copolymeric micelles of poly(styrene-alt-maleic anhydride) for combinatorial delivery of doxorubicin and plk-1 siRNA in cancer therapy

M. R. Aji Alex; Srivani Veeranarayanan; Aby Cheruvathoor Poulose; Chetan Nehate; D. Sakthi Kumar; Veena Koul, J. Mater. Chem. B. 7303 - 7313. 45. 4. 2016. https://doi.org/10.1039%2Fc6tb02094a . 10.1039/c6tb02094a . J. Mater. Chem. B

Quantification of zinc and lithium in zinc oxide quantum dots by atomic absorption spectroscopy

Baby, J.N.; Pramod, K.; John, S.; Aji Alex, M.R.; Suneesh, C.V.; Tahir, M.A., Research Journal of Pharmaceutical, Biological and Chemical Sciences. 973 - 977. 6. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951729927&partnerID=MN8TOARS . Research Journal of Pharmaceutical, Biological and Chemical Sciences

Synthesis and evaluation of cationically modified poly(styrene-alt-maleic anhydride) nanocarriers for intracellular gene delivery

Aji Alex, M.R.; Nagpal, N.; Kulshreshtha, R.; Koul, V., RSC Advances. 21931 - 21944. 28. 5. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923902351&partnerID=MN8TOARS . 10.1039/c5ra00409h . RSC Advances

Preparation and evaluation of tunable emission zinc oxide quantum dots for gene delivery

Baby, J.N.; Pramod, K.; John, S.; Aji Alex, M.R.; Suneesh, C.V.; Kapoor, S.; Tahir, M.A., International Journal of Pharmaceutical Sciences Review and Research. 191 - 194. 1. 35. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84949647796&partnerID=MN8TOARS . International Journal of Pharmaceutical Sciences Review and Research

Enhanced delivery of lopinavir to the CNS using Compritol <sup>®</sup>-based solid lipid nanoparticles

Alex, A.; Paul, W.; Chacko, A.J.; Sharma, C.P., Therapeutic Delivery. 25 - 35. 1. 2. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79954567170&partnerID=MN8TOARS . 10.4155/tde.10.96 . Therapeutic Delivery

Lopinavir loaded solid lipid nanoparticles (SLN) for intestinal lymphatic targeting

Aji Alex, M.R.; Chacko, A.J.; Jose, S.; Souto, E.B., European Journal of Pharmaceutical Sciences. 11 - 18. 1-2. 42. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650678527&partnerID=MN8TOARS . 10.1016/j.ejps.2010.10.002 . European Journal of Pharmaceutical Sciences

All projects

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Information of exclusive responsibility of the researcher 18-04-2024 , from platform CIÊNCIAVITAE.

2023/03/01 - 2024/06/30

Polymer brush grafted exosomes for microRNA delivery through blood brain barrier (BBB)

2022.02803.PTDC

Principal investigator

Universidade de Coimbra; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2022/05/01 - 2024/04/30

Design and development of exosomes with brush type architecture as RNA delivery vectors for active targeting of blood brain barrier (BBB)

101019325

Principal investigator

Universidade de Coimbra

Funders: European Commission

2020/02/11 - 2022/02/09

SIX-MONTH EFFECTIVE TREATMENT OF CORNEAL GRAFT REJECTION

R01EY027827

Post-doc

Virginia Commonwealth University Department of Pharmaceutics

Funders: National Institutes of Health

2020/11/07 - 2022/02/09

Bioequivalence study of generic formulations of tobramycin/dexamethasone in rabbit model

HHSF223201810114C

Post-doc

Virginia Commonwealth University

Funders: U.S. Food and Drug Administration

2020/02/10 - 2022/02/09

Novel Nor-LAAM formulations for treating opioid use disorders

DA048768-01A1

Post-doc

Virginia Commonwealth University

Funders: National Institutes of Health

2020/02/10 - 2022/02/09

Novel Nor-LAAM formulations for treating opioid use disorders

DA048768-01A1

Post-doc

Virginia Commonwealth University

Funders: National Institutes of Health

2018/03/20 - 2020/02/07

Development of cationic polymer brushes for efficient gene delivery applications

INRF-2017-179

Principal investigator

Queen Mary University of London - Mile End Campus

Funders: Commonwealth Secretariat

2017/09/20 - 2018/03/07

Artificial skin (Bio-inspired bi-layer polymeric hybrid scaffold) for burn injuries and trauma care

F.NO.41-2/2015-T.S.I (PT) (ANN.I SL.24)

Scientific Initiation Fellow

Indian Institute of Technology Delhi Center for Biomedical Engineering

Funders: India Ministry of Human Resource Development

2015/05/08 - 2018/05/07

Development of hybrid polymeric nanosystems for combinatorial targeted delivery of siRNA and drug in breast cancer therapy

BT/PR10191/NNT//28/717/2013

PhD Student Fellow

Indian Institute of Technology Delhi

Funders: Department of Biotechnology Ministry of Science and Technology

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