Ana Cristina Rosa da Silva

Effect of bioactive extracts from Eucalyptus globulus leaves in experimental models of Alzheimer’s disease

Moreira, Patrícia; Macedo, Jéssica; Matos, Patrícia; Bicker, Joana; Fortuna, Ana; Figueirinha, Artur; Salgueiro, Lígia; et al, Biomedicine & Pharmacotherapy. 181. 2024. https://doi.org/10.1016/j.biopha.2024.117652 . 10.1016/j.biopha.2024.117652 . published Biomedicine & Pharmacotherapy

Blocking the adverse outcome pathway of skin sensitization through a N-acetyl cysteine and lysine-loaded hydrogel

Brites, Gonçalo S.; Ferreira, Isabel; Sebastião, Ana I.; Sousa, Cátia; Silva, Ana Cristina Rosa da; Carrascal, Mylene; Oliveira, Rui C.; et al, Journal of Pharmaceutical Analysis. 2024. https://doi.org/10.1016/j.jpha.2024.101071 . 10.1016/j.jpha.2024.101071 . published Journal of Pharmaceutical Analysis

Road traffic noise exposure and its impact on health: evidence from animal and human studies—chronic stress, inflammation, and oxidative stress as key components of the complex downstream pathway underlying noise-induced non-auditory health effects

Arregi, Ane; Vegas, Oscar; Lertxundi, Aitana; Silva, Ana Cristina Rosa da; Ferreira, Isabel; Bereziartua, Ainhoa; Cruz, Maria Teresa; Lertxundi, Nerea, Environmental Science and Pollution Research. 46820 - 46839. 34. 31. 2024. https://doi.org/10.1007/s11356-024-33973-9 . 10.1007/s11356-024-33973-9 . published Environmental Science and Pollution Research

Intranasal irbesartan reverts cognitive decline and activates the PI3K/AKT pathway in an LPS-induced neuroinflammation mice model

Gouveia, Filipa; Fonseca, Carla; Silva, Ana Cristina Rosa da; Camins, Antoni; Teresa Cruz, M.; Ettcheto, Miren; Fortuna, Ana, International Immunopharmacology. 128. 2024. http://dx.doi.org/10.1016/j.intimp.2023.111471 . 10.1016/j.intimp.2023.111471 . published International Immunopharmacology

Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina rosmarinifolia L. Essential Oil from Portugal

Alves-Silva, Jorge M.; Gonçalves, Maria José; Silva, Ana Cristina Rosa da; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, Lígia, Antibiotics. 1. 12. 2023. http://dx.doi.org/10.3390/antibiotics12010179 . 10.3390/antibiotics12010179 . Antibiotics

Unveiling the Chemical Composition and Biological Properties of Salvia cacaliifolia Benth. Essential Oil

Alves-Silva, Jorge M.; Cocco, Emma; Piras, Alessandra; Gonçalves, Maria José; Silva, Ana Cristina Rosa da; Falconieri, Danilo; Porcedda, Silvia; et al, Plants. 2. 12. 2023. http://dx.doi.org/10.3390/plants12020359 . 10.3390/plants12020359 . Plants

Development of an in chemico high-throughput screening method for the identification of skin sensitization potential

Ferreira, Isabel; Brites, Gonçalo; Silva, Ana Cristina Rosa da; Caramelo, Francisco; Oliveiros, Bárbara; Neves, Bruno Miguel; Cruz, Maria Teresa, Archives of Toxicology. 2441 - 2451. 9. 97. 2023. http://dx.doi.org/10.1007/s00204-023-03550-z . 10.1007/s00204-023-03550-z . published Archives of Toxicology

Protective role of Portuguese natural mineral waters on skin aging: in vitro evaluation of anti-senescence and anti-oxidant properties

Vaz, CV; Oliveira, AS; Silva, Ana Cristina Rosa da; Cortes, L; Correia, S; Ferreira, R; Breitenfeld, L; et al, International Journal of Biometeorology. 2117 - 2131. 10. 66. 2022. http://dx.doi.org/10.1007/s00484-022-02345-8 . 10.1007/s00484-022-02345-8 . published International Journal of Biometeorology

Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes

Conte, Fernanda Lopes; Pereira, Ana Catarina; Brites, Gonçalo; Ferreira, Isabel; Silva, Ana Cristina; Sebastião, Ana Isabel; Matos, Patrícia; et al, Phytomedicine Plus. 2. 2. 2022. http://dx.doi.org/10.1016/j.phyplu.2022.100231 . 10.1016/j.phyplu.2022.100231 . published Phytomedicine Plus

Chemical composition and biological activity of essential oil of Teucrium scordium L. subsp. scordioides (Schreb.) Arcang. (Lamiaceae) from Sardinia Island (Italy)

Piras, Alessandra; Maccioni, Alfredo; Falconieri, Danilo; Porcedda, Silvia; Gonçalves, Maria José; Alves-Silva, Jorge M.; Silva, Ana; et al, Natural Product Research. 1 - 8. 2021. http://dx.doi.org/10.1080/14786419.2021.2018432 . 10.1080/14786419.2021.2018432 . published Natural Product Research

Therapies for Alzheimer’s disease: a metabolic perspective

Domingues, Raquel; Pereira, Claúdia; Cruz, Maria Teresa; Silva, Ana, Molecular Genetics and Metabolism. 2021. http://dx.doi.org/10.1016/j.ymgme.2021.01.011 . 10.1016/j.ymgme.2021.01.011 . published Molecular Genetics and Metabolism

Giardia lamblia Decreases NF-¿B p65RelA Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages

Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenço, Ágata; Cruz, Maria Teresa; Martins, João D.; Silva, Ana; Pereira, Sónia; Sousa, Maria do Céu, Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-63231-0 . 10.1038/s41598-020-63231-0 . Scientific Reports

Anti-inflammatory potential of Portuguese thermal waters

Silva, Ana Cristina Rosa da; Oliveira, A. S.; Vaz, C. V.; Correia, S.; Ferreira, R.; Breitenfeld, L.; Martinez-de-Oliveira, J.; et al, Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-79394-9 . 10.1038/s41598-020-79394-9 . published Scientific Reports

Evaluating skin sensitization via soft and hard multivariate modelling

Filipa A L S Silva; Gonçalo Brites; Isabel Ferreira; Silva, Ana Cristina Rosa da; Bruno Miguel Neves; Jorge L G F S Costa Pereira; Maria Teresa Cruz; et al, International Journal of Toxicology. 2020. http://dx.doi.org/10.1177/1091581820944395 . 10.1177/1091581820944395 . published International Journal of Toxicology

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; Martinez-de-Oliveira, José; et al, International Journal of Biometeorology. 2020. http://dx.doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . International Journal of Biometeorology

NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify

Sebastião, Ana Isabel; Ferreira, Isabel; Brites, Gonçalo; Silva, Ana Cristina Rosa da; Neves, Bruno Miguel; Teresa Cruz, Maria, Pharmaceutics. 9. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12090867 . 10.3390/pharmaceutics12090867 . published Pharmaceutics

Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-¿B Signaling Pathway

Catarino, Marcelo D.; Silva, Ana; Cruz, Maria T.; Mateus, Nuno; Silva, Artur M.S.; Cardoso, Susana M., International Journal of Molecular Sciences. 18. 21. 2020. http://dx.doi.org/10.3390/ijms21186897 . 10.3390/ijms21186897 . International Journal of Molecular Sciences

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Silva, Ana; Pereira, Marta; Carrascal, Mylène A.; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia; Resende, Rosa; et al, International Journal of Molecular Sciences. 20. 21. 2020. http://dx.doi.org/10.3390/ijms21207791 . 10.3390/ijms21207791 . published International Journal of Molecular Sciences

Allergic contact dermatitis: From pathophysiology to development of new preventive strategies

Brites, Gonçalo Sousa; Ferreira, Isabel; Sebastião, Ana Isabel; Silva, Ana; Carrascal, Mylene; Neves, Bruno Miguel; Cruz, Maria T., Pharmacological Research. 162. 2020. http://dx.doi.org/10.1016/j.phrs.2020.105282 . 10.1016/j.phrs.2020.105282 . published Pharmacological Research

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Ferreira, Sandra Saraiva; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; et al, Environmental Geochemistry and Health. 2019. http://dx.doi.org/10.1007/s10653-019-00473-6 . 10.1007/s10653-019-00473-6 . Environmental Geochemistry and Health

Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1

Ferreira, Isabel; Silva, Ana; Martins, João Demétrio; Neves, Bruno Miguel; Cruz, Maria Teresa, Redox Biology. 75 - 86. 16. 2018. http://dx.doi.org/10.1016/j.redox.2018.02.002 . 10.1016/j.redox.2018.02.002 . Redox Biology

Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease

Silva, A.C.; Ferreira, I.L.; Hayden, M.R.; Ferreiro, E.; Rego, A.C., Biochimica et Biophysica Acta - Molecular Basis of Disease. 34 - 44. 1. 1864. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031746642&partnerID=MN8TOARS . 10.1016/j.bbadis.2017.09.009 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

Almeida Paiva, Rafael; Martins-Marques, Tania; Jesus, Katia; Ribeiro-Rodrigues, Teresa; Zuzarte, Monica; Silva, Ana; Reis, Liliana; et al, Journal of Cellular and Molecular Medicine. 1137 - 1151. 2. 23. 2018. http://dx.doi.org/10.1111/jcmm.14014 . 10.1111/jcmm.14014 . Journal of Cellular and Molecular Medicine

Inflammasome in dendritic cells immunobiology: Implications to diseases and therapeutic strategies

Ferreira, I.; Liberal, J.; Martins, J.D.; Silva, A.; Neves, B.M.; Cruz, M.T., Current Drug Targets. 1003 - 1018. 9. 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022193483&partnerID=MN8TOARS . 10.2174/1389450117666160921144830 . Current Drug Targets

Adenosine diphosphate involvement in THP-1 maturation triggered by the contact allergen 1-fluoro-2,4-dinitrobenzene

Martins, J.D.; Silva, A.; Ferreira, I.; Gonçalo, M.; Custódio, J.B.A.; Lopes, M.C.; Domingues, M.R.M.; Neves, B.M.; Cruz, M.T., Toxicology Research. 1512 - 1521. 6. 5. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84993965439&partnerID=MN8TOARS . 10.1039/c6tx00240d . Toxicology Research

Phospholipidomic Profile Variation on THP-1 Cells Exposed to Skin or Respiratory Sensitizers and Respiratory Irritant

Martins, J.D.; Maciel, E.A.; Silva, A.; Ferreira, I.; Ricardo, F.; Domingues, P.; Neves, B.M.; Domingues, M.R.M.; Cruz, M.T., Journal of Cellular Physiology. 2639 - 2651. 12. 231. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983242587&partnerID=MN8TOARS . 10.1002/jcp.25365 . Journal of Cellular Physiology

Autophagy and inflammasome interplay

Martins, J.D.; Liberal, J.; Silva, A.; Ferreira, I.; Neves, B.M.; Cruz, M.T., DNA and Cell Biology. 274 - 281. 4. 34. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926611400&partnerID=MN8TOARS . 10.1089/dna.2014.2752 . DNA and Cell Biology

Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells

Gonçalo, M.; Martins, J.; Silva, A.; Neves, B.; Figueiredo, A.; Cruz, T.; Lopes, C., Journal of Applied Toxicology. 398 - 406. 4. 35. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923069689&partnerID=MN8TOARS . 10.1002/jat.3033 . Journal of Applied Toxicology

Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease

Silva, Ana Cristina Rosa da; Naia, L.; Dominguez, A.; Ribeiro, M.; Rodrigues, J.; Vieira, O.V.; Lessmann, V.; Rego, A.C., Neurodegenerative Diseases. 207 - 218. 4. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939565482&partnerID=MN8TOARS . 10.1159/000375447 . published Neurodegenerative Diseases

Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells

Silva, Ana Cristina Rosa da; Nunes, C.; Martins, J.; Dinis, T.C.P.; Lopes, C.; Neves, B.; Cruz, T., Free Radical Biology and Medicine. 238 - 246. 72. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901040063&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2014.04.005 . Free Radical Biology and Medicine

Oxidative stress-dependent activation of the eIF2a–ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner

Luís, Andreia; Martins, João Demétrio; Silva, Ana Cristina Rosa da; Ferreira, Isabel; Cruz, Maria Teresa; Neves, Bruno Miguel, Free Radical Biology and Medicine. 217 - 229. 77. 2014. https://doi.org/10.1016/j.freeradbiomed.2014.09.008 . 10.1016/j.freeradbiomed.2014.09.008 . published Free Radical Biology and Medicine

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic huntington's disease carriers

Silva, A.C.; Almeida, S.; Laço, M.; Duarte, A.I.; Domingues, J.; Oliveira, C.R.; Januário, C.; Rego, A.C., Mitochondrion. 801 - 809. 6. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887018742&partnerID=MN8TOARS . 10.1016/j.mito.2013.05.006 . Mitochondrion

Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells-protective effect oflcystamine and creatine

Ribeiro, M.; Silva, A.C.; Rodrigues, J.; Naia, L.; Rego, A.C., Toxicological Sciences. 487 - 499. 2. 136. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890357270&partnerID=MN8TOARS . 10.1093/toxsci/kft199 . Toxicological Sciences

Development of an in vitro dendritic cell-based test for skin sensitizer identification

Neves, B.M.; Rosa, S.C.; Martins, J.D.; Silva, A.; Goncìalo, M.; Lopes, M.C.; Cruz, M.T., Chemical Research in Toxicology. 368 - 378. 3. 26. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875168719&partnerID=MN8TOARS . 10.1021/tx300472d . Chemical Research in Toxicology

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype

Silva, Ana Cristina Rosa da; Pereira, Jorge; Oliveira, Catarina R.; Relvas, João Bettencourt; Rego, A. Cristina, Journal of Neuroscience Research. 1986 - 1996. 9. 87. 2009. http://dx.doi.org/10.1002/jnr.22041 . 10.1002/jnr.22041 . published Journal of Neuroscience Research