Ana Cristina Rosa da Silva

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Publications

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Information about journal articles, updated at 28-11-2021, from platform CIÊNCIAVITAE.

Therapies for Alzheimer’s disease: a metabolic perspective

Domingues, Raquel; Pereira, Claúdia; Cruz, Maria Teresa; Silva, Ana, Molecular Genetics and Metabolism. 2021. http://dx.doi.org/10.1016/j.ymgme.2021.01.011 . 10.1016/j.ymgme.2021.01.011 . published Molecular Genetics and Metabolism

Allergic contact dermatitis: From pathophysiology to development of new preventive strategies

Brites, Gonçalo Sousa; Ferreira, Isabel; Sebastião, Ana Isabel; Silva, Ana; Carrascal, Mylene; Neves, Bruno Miguel; Cruz, Maria T., Pharmacological Research. 162. 2020. http://dx.doi.org/10.1016/j.phrs.2020.105282 . 10.1016/j.phrs.2020.105282 . published Pharmacological Research

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Silva, Ana; Pereira, Marta; Carrascal, Mylène A.; Brites, Gonçalo; Neves, Bruno; Moreira, Patrícia; Resende, Rosa; et al, International Journal of Molecular Sciences. 20. 21. 2020. http://dx.doi.org/10.3390/ijms21207791 . 10.3390/ijms21207791 . published International Journal of Molecular Sciences

Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-¿B Signaling Pathway

Catarino, Marcelo D.; Silva, Ana; Cruz, Maria T.; Mateus, Nuno; Silva, Artur M.S.; Cardoso, Susana M., International Journal of Molecular Sciences. 18. 21. 2020. http://dx.doi.org/10.3390/ijms21186897 . 10.3390/ijms21186897 . International Journal of Molecular Sciences

NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify

Ana Isabel Sebastião; Isabel Ferreira; Gonçalo Brites; Silva, Ana Cristina Rosa da; Bruno Miguel Neves; Maria Teresa Cruz, Pharmaceutics. 2020. published Pharmaceutics

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; Martinez-de-Oliveira, José; et al, International Journal of Biometeorology. 2020. http://dx.doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . International Journal of Biometeorology

Evaluating skin sensitization via soft and hard multivariate modelling

Filipa A L S Silva; Gonçalo Brites; Isabel Ferreira; Silva, Ana Cristina Rosa da; Bruno Miguel Neves; Jorge L G F S Costa Pereira; Maria Teresa Cruz; et al, International Journal of Toxicology. 2020. http://dx.doi.org/10.1177/1091581820944395 . 10.1177/1091581820944395 . accepted International Journal of Toxicology

Anti-inflammatory potential of Portuguese Thermal Waters

Silva, Ana Cristina Rosa da; Ana Sofia Oliveira; Cátia V Vaz; Sara Correia; Raquel Ferreira; Luiza Breitenfeld; José Martinez-de-Oliveira; et al, Scientific Reports. 2020. accepted Scientific Reports

Giardia lamblia Decreases NF-¿B p65RelA Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages

Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenço, Ágata; Cruz, Maria Teresa; Martins, João D.; Silva, Ana; Pereira, Sónia; Sousa, Maria do Céu, Scientific Reports. 1. 10. 2020. http://dx.doi.org/10.1038/s41598-020-63231-0 . 10.1038/s41598-020-63231-0 . Scientific Reports

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, Ana Sofia; Vaz, Cátia Vicente; Silva, Ana; Ferreira, Sandra Saraiva; Correia, Sara; Ferreira, Raquel; Breitenfeld, Luiza; et al, Environmental Geochemistry and Health. 2019. http://dx.doi.org/10.1007/s10653-019-00473-6 . 10.1007/s10653-019-00473-6 . Environmental Geochemistry and Health

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

Almeida Paiva, Rafael; Martins-Marques, Tania; Jesus, Katia; Ribeiro-Rodrigues, Teresa; Zuzarte, Monica; Silva, Ana; Reis, Liliana; et al, Journal of Cellular and Molecular Medicine. 1137 - 1151. 2. 23. 2018. http://dx.doi.org/10.1111/jcmm.14014 . 10.1111/jcmm.14014 . Journal of Cellular and Molecular Medicine

Characterization of subventricular zone-derived progenitor cells from mild and late symptomatic YAC128 mouse model of Huntington's disease

Silva, A.C.; Ferreira, I.L.; Hayden, M.R.; Ferreiro, E.; Rego, A.C., Biochimica et Biophysica Acta - Molecular Basis of Disease. 34 - 44. 1. 1864. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031746642&partnerID=MN8TOARS . 10.1016/j.bbadis.2017.09.009 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1

Ferreira, Isabel; Silva, Ana; Martins, João Demétrio; Neves, Bruno Miguel; Cruz, Maria Teresa, Redox Biology. 75 - 86. 16. 2018. http://dx.doi.org/10.1016/j.redox.2018.02.002 . 10.1016/j.redox.2018.02.002 . Redox Biology

Inflammasome in dendritic cells immunobiology: Implications to diseases and therapeutic strategies

Ferreira, I.; Liberal, J.; Martins, J.D.; Silva, A.; Neves, B.M.; Cruz, M.T., Current Drug Targets. 1003 - 1018. 9. 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022193483&partnerID=MN8TOARS . 10.2174/1389450117666160921144830 . Current Drug Targets

Adenosine diphosphate involvement in THP-1 maturation triggered by the contact allergen 1-fluoro-2,4-dinitrobenzene

Martins, J.D.; Silva, A.; Ferreira, I.; Gonçalo, M.; Custódio, J.B.A.; Lopes, M.C.; Domingues, M.R.M.; Neves, B.M.; Cruz, M.T., Toxicology Research. 1512 - 1521. 6. 5. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84993965439&partnerID=MN8TOARS . 10.1039/c6tx00240d . Toxicology Research

Phospholipidomic Profile Variation on THP-1 Cells Exposed to Skin or Respiratory Sensitizers and Respiratory Irritant

Martins, J.D.; Maciel, E.A.; Silva, A.; Ferreira, I.; Ricardo, F.; Domingues, P.; Neves, B.M.; Domingues, M.R.M.; Cruz, M.T., Journal of Cellular Physiology. 2639 - 2651. 12. 231. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983242587&partnerID=MN8TOARS . 10.1002/jcp.25365 . Journal of Cellular Physiology

Erratum: Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntingtons Disease (Neurodegenerative Diseases (2015) 15 (207-218) DOI:10.1159/000375447)

Silva, A.; Naia, L.; Dominguez, A.; Ribeiro, M.; Rodrigues, J.; Vieira, O.V.; Lessmann, V.; Rego, A.C., Neurodegenerative Diseases. 4. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939538133&partnerID=MN8TOARS . 10.1159/000433587 . Neurodegenerative Diseases

Errautm: 'Oxidative stress-dependent activation of the eIF2a-ATF4 unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner': (Free Radical Biology and M (2014) 77 (217-229))

Luís, A.; Martins, J.D.; Silva, A.; Ferreira, I.; Cruz, M.T.; Neves, B.M., Free Radical Biology and Medicine. 82. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939934316&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2015.01.009 . Free Radical Biology and Medicine

Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells

Gonçalo, M.; Martins, J.; Silva, A.; Neves, B.; Figueiredo, A.; Cruz, T.; Lopes, C., Journal of Applied Toxicology. 398 - 406. 4. 35. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923069689&partnerID=MN8TOARS . 10.1002/jat.3033 . Journal of Applied Toxicology

Overexpression of BDNF and Full-Length TrkB Receptor Ameliorate Striatal Neural Survival in Huntington's Disease

Silva, A.; Naia, L.; Dominguez, A.; Ribeiro, M.; Rodrigues, J.; Vieira, O.V.; Lessmann, V.; Rego, A.C., Neurodegenerative Diseases. 207 - 218. 4. 15. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939565482&partnerID=MN8TOARS . 10.1159/000375447 . Neurodegenerative Diseases

Autophagy and inflammasome interplay

Martins, J.D.; Liberal, J.; Silva, A.; Ferreira, I.; Neves, B.M.; Cruz, M.T., DNA and Cell Biology. 274 - 281. 4. 34. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926611400&partnerID=MN8TOARS . 10.1089/dna.2014.2752 . DNA and Cell Biology

Oxidative stress-dependent activation of the eIF2a-ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner

Luís, A.; Martins, J.D.; Silva, A.; Ferreira, I.; Cruz, M.T.; Neves, B.M., Free Radical Biology and Medicine. 217 - 229. 77. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908387127&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2014.09.008 . Free Radical Biology and Medicine

Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells

Silva, A.; Nunes, C.; Martins, J.; Dinis, T.C.P.; Lopes, C.; Neves, B.; Cruz, T., Free Radical Biology and Medicine. 238 - 246. 72. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901040063&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2014.04.005 . Free Radical Biology and Medicine

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic huntington's disease carriers

Silva, A.C.; Almeida, S.; Laço, M.; Duarte, A.I.; Domingues, J.; Oliveira, C.R.; Januário, C.; Rego, A.C., Mitochondrion. 801 - 809. 6. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887018742&partnerID=MN8TOARS . 10.1016/j.mito.2013.05.006 . Mitochondrion

Oxidizing effects of exogenous stressors in Huntington's disease knock-in striatal cells-protective effect oflcystamine and creatine

Ribeiro, M.; Silva, A.C.; Rodrigues, J.; Naia, L.; Rego, A.C., Toxicological Sciences. 487 - 499. 2. 136. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890357270&partnerID=MN8TOARS . 10.1093/toxsci/kft199 . Toxicological Sciences

Development of an in vitro dendritic cell-based test for skin sensitizer identification

Neves, B.M.; Rosa, S.C.; Martins, J.D.; Silva, A.; Goncìalo, M.; Lopes, M.C.; Cruz, M.T., Chemical Research in Toxicology. 368 - 378. 3. 26. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875168719&partnerID=MN8TOARS . 10.1021/tx300472d . Chemical Research in Toxicology

BDNF and extracellular matrix regulate differentiation of mice neurosphere-derived cells into a GABAergic neuronal phenotype

Silva, Ana; Pereira, Jorge; Oliveira, Catarina R.; Relvas, João Bettencourt; Rego, A. Cristina, Journal of Neuroscience Research. 1986 - 1996. 9. 87. 2009. 10.1002/jnr.22041 . published Journal of Neuroscience Research

All projects

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Information of exclusive responsibility of the researcher 28-11-2021 , from platform CIÊNCIAVITAE.

2018/09 - 2021/07

Skin allergens: molecules with an improbable therapeutic application for Alzheimer’s disease

CENTRO-01-0145-FEDER-029369

Researcher

Funders: Fundação para a Ciência e a Tecnologia

2017/06 - 2018/09

Study of the therapeutic properties of thermal waters - dermocosmetic

CENTRO-04-3928-FEDER-000010

Master Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Faculdade de Farmácia

2014 - 2015

Exosomes: putative biomarkers for respiratory and cutaneous allergens hazard

PRIME-XS 262067

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2014 - 2015

In chemico, in silico and in vitro modeling to predict human respiratory allergens

CAAT Project #2014-07

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Johns Hopkins University Center for Alternatives to Animal Testing

2014/05 - 2015/06

ToxVitroTesting

QREN nº.38977

Post-doc Fellow

Toxfinder Lda

2012/04/01 - 2013

In vitro alternative approach for chemical skin sensitization hazard: an EU legislation demand

PTDC/SAL-OSM/099762/2008

Master Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2011 - 2012

BDNF medeia protecção e diferenciação neuronal na doença de Huntington

PEI-HDCR01

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Universidade de Coimbra Faculdade de Medicina

2010 - 2012

Analysis of transcription deregulation in brain and peripheral Huntington’s disease models – influence of modulating histone deacetylases

PTDC/SAU-FCF/108056/2008

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2006 - 2007

Mitochondrial-dependent cell death control through transcription regulation in the presence of FK506 and BDNF – protective role in Huntington’s disease

POCI/SAU-NEU/57310/2004

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2003 - 2004

Serra de Monfurado. Conservação e valorização do Património Natural - Fauna

N/A

Research Fellow

Universidade de Évora

Funders: Comissão de Coordenação e Desenvolvimento Regional do Alentejo

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