Cláudia Cavadas

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Overview

Cláudia Cavadas (CC) is PharmD and PhD in Pharmacology, University of Coimbra, Portugal. CC is the head of the Neuroendocrinology and Aging Group at CNC - Center for Neuroscience and Cell Biology. Her research group hasthe mission is to contribute to develop new knowledge in the aging field, namely to demonstrate that neuroendocrine system and related mechanisms can be targeted in experimental models to delay manifestations of aging and age-related disorders. CC successfully supervised 13 PhD students and 48 Master students, attracted around 2 M€ of funding, has around 100 scientific publications and was invited speaker in relevant conferences and research institutions. CC is Associated Professor at the Faculty of Pharmacy of the University of Coimbra. During 29 years of teaching experience at the Faculty of Pharmacy, CC coordinates and is professor of different subjects such as Pharmacology, Histology and Embryology, Physiology, Pathophysiology, etc. And since 2019, CC coordinates the subject “Research and Science communication. Cláudia Cavadas has been very committed to promote science to non-academic/scientific public and organized and participated in several science communication and outreach activities. Claudia Cavadas is the former Vice Rector of the University of Coimbra (2019-2023), in charge of Research, and Director of the Institute of Interdisciplinary Research; during that time CC launched and coordinated several initiatives as the Strategic areas of Research of the University of Coimbra, Doctoral Schools@UC, Three Minutes Thesis Competition, ERC@UC, MarieCurie@UC, etc… CC has also been committed to promote inclusion and diversity in research, and she organized the initiative GendER@UC and coordinates the funded project GendER@UC-EAA Grant. Research IDs and Websites Orcid ID: 0000-0001-8020-9266 Ciencia ID: D413-2E77-4BDE Neuroendocrinology and Aging Group: https://www.cnc.uc.pt/en/research-group/neuroendocronology-and-aging Other: https://claudiacavadas.weebly.com/

Publications

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Information about journal articles, updated at 19-05-2024, from platform CIÊNCIAVITAE.

Modeling hypothalamic pathophysiology in vitro for metabolic, circadian, and sleep disorders

Cavadas, Claudia; Álvaro, Ana Rita ; Leal, Helena; Carvalhas de Almeida, Catarina, Trends Endocrinolology Metabolism. 2024. https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(24)00001-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1043276024000018%3Fshowall%3Dtrue . published Trends Endocrinolology Metabolism

Ghrelin delays premature aging in <scp>Hutchinson-Gilford</scp> progeria syndrome

Ferreira-Marques, Marisa; Carvalho, André; Franco, Ana Catarina; Leal, Ana; Botelho, Mariana; Carmo-Silva, Sara; Águas, Rodolfo; et al, Aging Cell. 12. 22. 2023. http://dx.doi.org/10.1111/acel.13983 . 10.1111/acel.13983 . published Aging Cell

Lipodystrophy as a target to delay premature aging

Daniela G. Costa; Marisa Ferreira-Marques; Cláudia Cavadas, Trends in Endocrinology & Metabolism. 2023. https://doi.org/10.1016/j.tem.2023.10.006 . 10.1016/j.tem.2023.10.006 . Trends in Endocrinology & Metabolism

Cellular Senescence: From Mechanisms to Current Biomarkers and Senotherapies

Lucas, Vasco; Cavadas, Cláudia; Aveleira, Célia Alexandra, Pharmacological Reviews. 675 - 713. 4. 75. 2023. http://dx.doi.org/10.1124/pharmrev.122.000622 . 10.1124/pharmrev.122.000622 . Pharmacological Reviews

Primary cilia shape hallmarks of health and aging.

Silva DF; Cavadas C; Claudia Cavadas, Trends in molecular medicine. 2023. https://doi.org/10.1016/j.molmed.2023.04.001 . 10.1016/j.molmed.2023.04.001 . Trends in molecular medicine

Ataxin-2 in the hypothalamus at the crossroads between metabolism and clock genes

Sara Carmo-Silva; Marisa Ferreira-Marques; Clévio Nóbrega; Mariana Botelho; Daniela Costa; Célia A Aveleira; Stefan M Pulst; Luís Pereira de Almeida; Claudia Cavadas, Journal of Molecular Endocrinology. 2023. https://doi.org/10.1530/JME-21-0272 . 10.1530/JME-21-0272 . Journal of Molecular Endocrinology

SIRT1 activation and its circadian clock control: a promising approach against (frailty in) neurodegenerative disorders

Rodrigo F. N. Ribeiro; Dina Pereira; Luis Pereira de Almeida; Maria Manuel C. Silva; Cláudia Cavadas, Aging Clinical and Experimental Research. 2022. https://doi.org/10.1007/s40520-022-02257-y . 10.1007/s40520-022-02257-y . Aging Clinical and Experimental Research

Ataxin-2 in the hypothalamus at the crossroads between metabolism & circadian rhythm (under revision)

Carmo-Silva, Sara; Ferreira-Marques, M; Nóbrega, Clévio David Rodrigues ; Botelho M; Costa, D; Aveleira C; Pulst, Stefan; Almeida, Luís Pereira de; Cavadas, Claudia, Journal of Molecular Endocrinology. 2022. under revision Journal of Molecular Endocrinology

Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis.

Gaspar LS; Santos-Carvalho A; Santos B; Carvalhas-Almeida C; Barros-Viegas AT; Oliveiros B; Donato H; et al, Sleep medicine reviews. 2022. http://europepmc.org/abstract/med/35753150 . 10.1016/j.smrv.2022.101659 . Sleep medicine reviews

Skin senescence: mechanisms and impact on whole-body aging

Ana Catarina Franco; Célia Aveleira; Cláudia Cavadas, Trends in Molecular Medicine. 2022. https://doi.org/10.1016/j.molmed.2021.12.003 . 10.1016/j.molmed.2021.12.003 . Trends in Molecular Medicine

A look on food intake and satiety: from humans to rodent models

Cavadas, Claudia; Almeida, Cláudia; Cavadas, Cláudia; Carmo-Silva, Sara, Nutrition Reviews. 1942 - 1957. 8. 80. 2022. http://dx.doi.org/10.1093/nutrit/nuac010 . 10.1093/nutrit/nuac010 . Nutrition Reviews

The impact of insomnia on frailty and the hallmarks of aging

Catarina Carvalhas-Almeida; Cláudia Cavadas; Ana Rita Álvaro, Aging Clinical and Experimental Research. 2022. https://doi.org/10.1007/s40520-022-02310-w . 10.1007/s40520-022-02310-w . Aging Clinical and Experimental Research

SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway.

Leal H; Cardoso J; Valério P; Quatorze M; Carmona V; Cunha-Santos J; Pereira de Almeida L; et al, International journal of molecular sciences. 2022. http://europepmc.org/abstract/med/35743232 . 10.3390/ijms23126790 . International journal of molecular sciences

PET Imaging of the Neuropeptide Y System: A Systematic Review.

Fonseca ICF; Castelo-Branco M; Cavadas C; Abrunhosa AJ, Molecules (Basel, Switzerland). 2022. http://europepmc.org/abstract/med/35744852 . 10.3390/molecules27123726 . Molecules (Basel, Switzerland)

PI3K/AKT/MTOR and ERK1/2-MAPK signaling pathways are involved in autophagy stimulation induced by caloric restriction or caloric restriction mimetics in cortical neurons

Cavadas, Claudia, Aging. 2021. https://doi.org/10.18632/aging.202805 . 10.18632/aging.202805 . Aging

Small-molecule modulators of the circadian clock: Pharmacological potentials in circadian-related diseases

Ribeiro, R.F.N.; Cavadas, C.; Silva, M.M.C., Drug Discovery Today. 1620 - 1641. 7. 26. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85104421181&partnerID=MN8TOARS . 10.1016/j.drudis.2021.03.015 . Drug Discovery Today

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.

Cavadas, Claudia, Autophagy. 2021. https://doi.org/10.1080/15548627.2020.1797280 . 10.1080/15548627.2020.1797280 . Autophagy

Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea (EBioMedicine)

Laetitia S. Gaspar; Janina Hesse; Müge Yalçin; Bárbara Santos; Catarina Carvalhas-Almeida; Mafalda Ferreira; Joaquim Moita; et al, EBioMedicine. 2021. https://doi.org/10.1016/j.ebiom.2021.103248 . 10.1016/j.ebiom.2021.103248 . in press EBioMedicine

Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease.

Cavadas, Claudia, Scientific reports. 2021. https://europepmc.org/articles/PMC7870889 . 10.1038/s41598-021-82339-5 . Scientific reports

Blueberry counteracts prediabetes in a hypercaloric diet-induced rat model and rescues hepatic mitochondrial bioenergetics

Nunes, S.; Viana, S.D.; Preguiça, I.; Alves, A.; Fernandes, R.; Teodoro, J.S.; Matos, P.; et al, Nutrients. 12. 13. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85119606449&partnerID=MN8TOARS . 10.3390/nu13124192 . Nutrients

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

Aveleira, Célia A; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luís; Cavadas, Cláudia, The Journals of Gerontology: Series A. 1073 - 1078. 6. 75. 2020. http://dx.doi.org/10.1093/gerona/glz280 . 10.1093/gerona/glz280 . published The Journals of Gerontology: Series A

Trehalose alleviates the phenotype of Machado-Joseph disease mouse models

Santana, M.M.; Paixão, S.; Cunha-Santos, J.; Silva, T.P.; Trevino-Garcia, A.; Gaspar, L.S.; Nóbrega, C.; et al, Journal of Translational Medicine. 1. 18. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85083210032&partnerID=MN8TOARS . 10.1186/s12967-020-02302-2 . Journal of Translational Medicine

Blueberry consumption challenges hepatic mitochondrial bioenergetics and elicits transcriptomics reprogramming in healthy wistar rats

Nunes, S.; Viana, S.D.; Preguiça, I.; Alves, A.; Fernandes, R.; Teodoro, J.S.; Figueirinha, A.; et al, Pharmaceutics. 1 - 29. 11. 12. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096072381&partnerID=MN8TOARS . 10.3390/pharmaceutics12111094 . Pharmaceutics

The Superpowers of Our Sleep

Gaspar, Laetitia S.; Santos, Bárbara; Barros-Viegas, Ana Teresa; Cardoso, João; Varela Amaral, Sara; Carvalhas-Almeida, Catarina; Santos-Carvalho, Ana; Cavadas, Cláudia; Álvaro, Ana Rita, Frontiers for Young Minds. 8. 2020. http://dx.doi.org/10.3389/frym.2020.540052 . 10.3389/frym.2020.540052 . published Frontiers for Young Minds

Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?

Cavadas, Claudia, Pharmacological research. 2020. https://doi.org/10.1016/j.phrs.2020.105369 . 10.1016/j.phrs.2020.105369 . Pharmacological research

Dichotomous Sirtuins: Implications for Drug Discovery in Neurodegenerative and Cardiometabolic Diseases

Cavadas, Claudia, Trends in Pharmacological Sciences. 2019. http://dx.doi.org/10.1016/j.tips.2019.09.003 . 10.1016/j.tips.2019.09.003 . Trends in Pharmacological Sciences

The importance of determining circadian parameters in pharmacological studies

Laetitia S. Gaspar; Ana Rita Álvaro; Sara Carmo-Silva; Alexandrina Ferreira Mendes; Angela Relógio; Cláudia Cavadas, British Journal of Pharmacology. 2019. https://doi.org/10.1111/bph.14712 . 10.1111/bph.14712 . British Journal of Pharmacology

Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice

Marques, A.P.; Cunha-Santos, J.; Leal, H.; Sousa-Ferreira, L.; Pereira de Almeida, L.; Cavadas, C.; Rosmaninho-Salgado, J., Biochimica et Biophysica Acta - General Subjects. 403 - 413. 3. 1862. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85037668547&partnerID=MN8TOARS . 10.1016/j.bbagen.2017.11.012 . Biochimica et Biophysica Acta - General Subjects

In vitro susceptibility of Trypanosoma brucei brucei to selected essential oils and their major components

Costa, S.; Cavadas, C.; Cavaleiro, C.; Salgueiro, L.; do Céu Sousa, M., Experimental Parasitology. 34 - 40. 190. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85047422613&partnerID=MN8TOARS . 10.1016/j.exppara.2018.05.002 . Experimental Parasitology

Role of Beta-adrenergic Receptors and Sirtuin Signaling in the Heart During Aging, Heart Failure, and Adaptation to Stress

Spadari, R.C.; Cavadas, C.; de Carvalho, A.E.T.S.; Ortolani, D.; de Moura, A.L.; Vassalo, P.F., Cellular and Molecular Neurobiology. 109 - 120. 1. 38. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032021647&partnerID=MN8TOARS . 10.1007/s10571-017-0557-2 . Cellular and Molecular Neurobiology

The NAD<sup>+</sup>-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes

Lemos, V.; de Oliveira, R.M.; Naia, L.; Szegö, E.; Ramos, E.; Pinho, S.; Magro, F.; et al, Human Molecular Genetics. 4105 - 4117. 21. 26. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034211658&partnerID=MN8TOARS . 10.1093/hmg/ddx298 . Human Molecular Genetics

Unraveling the Role of Ataxin-2 in Metabolism

Carmo-Silva, S.; Nobrega, C.; Pereira de Almeida, L.; Cavadas, C., Trends in Endocrinology and Metabolism. 309 - 318. 4. 28. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85009726744&partnerID=MN8TOARS . 10.1016/j.tem.2016.12.006 . Trends in Endocrinology and Metabolism

Obstructive Sleep Apnea and Hallmarks of Aging

Gaspar, Laetitia S.; Álvaro, Ana Rita; Moita, Joaquim; Cavadas, Cláudia, Trends in Molecular Medicine. 675 - 692. 8. 23. 2017. http://dx.doi.org/10.1016/j.molmed.2017.06.006 . 10.1016/j.molmed.2017.06.006 . published Trends in Molecular Medicine

Hypoxia mimetic induces lipid accumulation through mitochondrial dysfunction and stimulates autophagy in murine preadipocyte cell line

Ana Patrícia Marques; Joana Rosmaninho-Salgado; Marta Estrada; Vera Cortez; Rui Jorge Nobre; Cláudia Cavadas, Biochimica et Biophysica Acta (BBA) - General Subjects. 673 - 682. 3. 1861. 2017. https://doi.org/10.1016/j.bbagen.2016.12.005 . 10.1016/j.bbagen.2016.12.005 . Biochimica et Biophysica Acta (BBA) - General Subjects

Corrigendum to "Intracellular mechanisms coupled to NPY Y<inf>2</inf> and Y<inf>5</inf> receptor activation and lipid accumulation in murine adipocytes" [neuropeptides 46/6 (2012) 359-366]

Rosmaninho-Salgado, J.; Cortez, V.; Estrada, M.; Santana, M.M.; Gonçalves, A.; Marques, A.P.; Cavadas, C., Neuropeptides. 101 - 101. 57. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84950130030&partnerID=MN8TOARS . 10.1016/j.npep.2015.11.089 . Neuropeptides

The pathophysiology of defective proteostasis in the hypothalamus — from obesity to ageing

Cavadas, Cláudia; Aveleira, Célia A.; Souza, Gabriela F. P.; Velloso, Lício A., Nature Reviews Endocrinology. 723 - 733. 12. 12. 2016. http://dx.doi.org/10.1038/nrendo.2016.107 . 10.1038/nrendo.2016.107 . Nature Reviews Endocrinology

Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases

Joana Duarte-Neves; Luís Pereira de Almeida; Cláudia Cavadas, Neurobiology of Disease. 210 - 224. 95. 2016. https://doi.org/10.1016%2Fj.nbd.2016.07.022 . 10.1016/j.nbd.2016.07.022 . Neurobiology of Disease

Antileishmanial activity of antiretroviral drugs combined with miltefosine

Costa, Sonya; Machado, Marisa; Cavadas, Cláudia; do Céu Sousa, Maria, Parasitology Research. 3881 - 3887. 10. 115. 2016. http://dx.doi.org/10.1007/s00436-016-5153-8 . 10.1007/s00436-016-5153-8 . published Parasitology Research

Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation.

Ferreira-Marques M; Aveleira CA; Carmo-Silva S; Botelho M; Pereira de Almeida L; Cavadas C; Ferreira-Marques, Marisa; et al, Aging. 1470 - 1484. 7. 8. 2016. http://europepmc.org/abstract/med/27441412 . 10.18632/aging.100996 . Aging

Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway

Cunha-Santos, J.; Duarte-Neves, J.; Carmona, V.; Guarente, L.; De Almeida, L.P.; Cavadas, C., Nature Communications. 7. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84968928647&partnerID=MN8TOARS . 10.1038/ncomms11445 . Nature Communications

The Adenosinergic System in Diabetic Retinopathy

Vindeirinho, J.; Santiago, A. R.; Cavadas, C.; Ambrósio, A. F.; Santos, P. F., Journal of Diabetes Research. 1 - 8. 2016. 2016. http://dx.doi.org/10.1155/2016/4270301 . 10.1155/2016/4270301 . published Journal of Diabetes Research

Hypothalamic involvement in premature aging laminopathies

Cavadas, Claudia; Cavadas C, Orphanet Journal of Rare Diseases. Suppl 2. 10. 2015. http://dx.doi.org/10.1186/1750-1172-10-s2-o6 . 10.1186/1750-1172-10-s2-o6 . published Orphanet Journal of Rare Diseases

Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress

Santana, M.M.; Rosmaninho-Salgado, J.; Cortez, V.; Pereira, F.C.; Kaster, M.P.; Aveleira, C.A.; Ferreira, M.; et al, European Neuropsychopharmacology. 1753 - 1766. 10. 25. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943267584&partnerID=MN8TOARS . 10.1016/j.euroneuro.2015.06.013 . European Neuropsychopharmacology

Neuropeptide Y system in the retina: From localization to function

Santos-Carvalho, Ana; Ambrósio, António Francisco; Cavadas, Cláudia, Progress in Retinal and Eye Research. 19 - 37. 47. 2015. http://dx.doi.org/10.1016/j.preteyeres.2015.03.001 . 10.1016/j.preteyeres.2015.03.001 . published Progress in Retinal and Eye Research

Neuropeptide Y stimulates autophagy in hypothalamic neurons

Aveleira, Célia A.; Botelho, Mariana; Carmo-Silva, Sara; Pascoal, Jorge F.; Ferreira-Marques, Marisa; Nóbrega, Clévio; Cortes, Luísa; et al, Proceedings of the National Academy of Sciences. E1642 - E1651. 13. 112. 2015. http://dx.doi.org/10.1073/pnas.1416609112 . 10.1073/pnas.1416609112 . published Proceedings of the National Academy of Sciences

NPY/neuropeptide Y enhances autophagy in the hypothalamus: a mechanism to delay aging?

Aveleira, Célia A; Botelho, Mariana; Cavadas, Cláudia, Autophagy. 1431 - 1433. 8. 11. 2015. http://dx.doi.org/10.1080/15548627.2015.1062202 . 10.1080/15548627.2015.1062202 . published Autophagy

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph disease

Duarte-Neves, Joana; Gonçalves, Nélio; Cunha-Santos, Janete; Simões, Ana Teresa; den Dunnen, Wilfred F.A.; Hirai, Hirokazu; Kügler, Sebastian; Cavadas, Cláudia; Pereira de Almeida, Luís, Human Molecular Genetics. 5451 - 5463. 19. 24. 2015. http://dx.doi.org/10.1093/hmg/ddv271 . 10.1093/hmg/ddv271 . published Human Molecular Genetics

Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective ActionsIn Vitro

Martins, João; Elvas, Filipe; Brudzewsky, Dan; Martins, Tânia; Kolomiets, Bogdan; Tralhão, Pedro; Gøtzsche, Casper R.; et al, ASN Neuro. 4. 7. 2015. http://dx.doi.org/10.1177/1759091415598292 . 10.1177/1759091415598292 . published ASN Neuro

Neuropeptide Y: An Anti-Aging Player?

Botelho, Mariana; Cavadas, Cláudia, Trends in Neurosciences. 701 - 711. 11. 38. 2015. http://dx.doi.org/10.1016/j.tins.2015.08.012 . 10.1016/j.tins.2015.08.012 . published Trends in Neurosciences

Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism

Gomes, Pedro; Fleming Outeiro, Tiago; Cavadas, Cláudia, Trends in Pharmacological Sciences. 756 - 768. 11. 36. 2015. http://dx.doi.org/10.1016/j.tips.2015.08.001 . 10.1016/j.tips.2015.08.001 . published Trends in Pharmacological Sciences

Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress

Faria, R.; Santana, M.M.; Aveleira, C.A.; Simões, C.; Maciel, E.; Melo, T.; Santinha, D.; et al, Neuroscience. 1 - 11. 273. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901323540&partnerID=MN8TOARS . 10.1016/j.neuroscience.2014.04.042 . Neuroscience

Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection

Santos-Carvalho, A.; Álvaro, A.R.; Martins, J.; Ambrósio, A.F.; Cavadas, C., Progress in Neurobiology. 70 - 79. 112. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890802011&partnerID=MN8TOARS . 10.1016/j.pneurobio.2013.10.002 . Progress in Neurobiology

Role of hypothalamic neurogenesis in feeding regulation

Sousa-Ferreira, L.; Almeida, L.P.D.; Cavadas, C., Trends in Endocrinology and Metabolism. 80 - 88. 2. 25. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892986633&partnerID=MN8TOARS . 10.1016/j.tem.2013.10.005 . Trends in Endocrinology and Metabolism

Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro

Sousa-Ferreira, Lígia; Aveleira, Célia; Botelho, Mariana; Álvaro, Ana Rita; Pereira de Almeida, Luís; Cavadas, Cláudia, PLoS ONE. 3. 9. 2014. http://dx.doi.org/10.1371/journal.pone.0088917 . 10.1371/journal.pone.0088917 . accepted PLoS ONE

Effect of Diabetes/Hyperglycemia on the Rat Retinal Adenosinergic System

Vindeirinho, J.; Costa, G.N.; Correia, M.B.; Cavadas, C.; Santos, P.F., PLoS ONE. 6. 8. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879548830&partnerID=MN8TOARS . 10.1371/journal.pone.0067499 . PLoS ONE

Progenitor cells in chromospheres: In response to Arthur S. Tischler

Santana, M.M.; Ehrhart-Bornstein, M.; Cavadas, C., Stem Cells Translational Medicine. 1020 - 1021. 12. 2. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888415377&partnerID=MN8TOARS . 10.5966/sctm.2013-0062 . Stem Cells Translational Medicine

Neuropeptide y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate

Santos-Carvalho, A.; Elvas, F.; Álvaro, A.R.; Ambrósio, A.F.; Cavadas, C., Cell Death and Disease. 5. 4. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879394627&partnerID=MN8TOARS . 10.1038/cddis.2013.160 . Cell Death and Disease

Neuropeptide Y receptors Y1 and Y2 are present in neurons and glial cells in rat retinal cells in culture

Santos-Carvalho, A.; Aveleira, C.A.; Elvas, F.; Ambrósio, A.F.; Cavadas, C., Investigative Ophthalmology and Visual Science. 429 - 443. 1. 54. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874719907&partnerID=MN8TOARS . 10.1167/iovs.12-10776 . Investigative Ophthalmology and Visual Science

Dipeptidyl-peptidase-IV by cleaving neuropeptide y induces lipid accumulation and PPAR-¿ expression

Cavadas, Claudia, BBA. 49 - 54. 1. 37. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865246554&partnerID=MN8TOARS . 10.1016/j.peptides.2012.06.014 . BBA

Isolation, characterization, and differentiation of progenitor cells from human adult adrenal medulla

Santana, M.M.; Chung, K.-F.; Vukicevic, V.; Rosmaninho-Salgado, J.; Kanczkowski, W.; Cortez, V.; Hackmann, K.; et al, Stem Cells Translational Medicine. 783 - 791. 11. 1. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873024306&partnerID=MN8TOARS . 10.5966/sctm.2012-0022 . Stem Cells Translational Medicine

Intracellular mechanisms coupled to NPY Y2 and Y5 receptor activation and lipid accumulation in murine adipocytes

Rosmaninho-Salgado, J.; Cortez, V.; Estrada, M.; Santana, M.M.; Gonçalves, A.; Marques, A.P.; Cavadas, C., Neuropeptides. 359 - 366. 6. 46. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84869870468&partnerID=MN8TOARS . 10.1016/j.npep.2012.08.006 . Neuropeptides

Regulation of catecholamine release in human adrenal chromaffin cells by ß-adrenoceptors

Cortez, V.; Santana, M.; Marques, A.P.; Mota, A.; Rosmaninho-Salgado, J.; Cavadas, C., Neurochemistry International. 387 - 393. 4. 60. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857026869&partnerID=MN8TOARS . 10.1016/j.neuint.2011.12.018 . Neurochemistry International

Contribution of TNF receptor 1 to retinal neural cell death induced by elevated glucose

Costa, G.N.; Vindeirinho, J.; Cavadas, C.; Ambrósio, A.F.; Santos, P.F., Molecular and Cellular Neuroscience. 113 - 123. 1. 50. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860624256&partnerID=MN8TOARS . 10.1016/j.mcn.2012.04.003 . Molecular and Cellular Neuroscience

Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and orexin-a and differentiate to functional neurons

Sousa-Ferreira, L.; Álvaro, A.R.; Aveleira, C.; Santana, M.; Brandão, I.; Kügler, S.; de Almeida, L.P.; Cavadas, C., PLoS ONE. 5. 6. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955917559&partnerID=MN8TOARS . 10.1371/journal.pone.0019745 . PLoS ONE

Adipose Tissue Changes Induced By the DPPIV Inhibitors (Gliptins): In Vivo and In Vitro Studies

Salgado, Joana; Estrada, Marta; Marques, Ana; Cortez, Vera; Reis, Flavio; Pereira, Frederico; Santana, Magda; Cavadas, Claudia, Obesity. 2011. https://publons.com/wos-op/publon/33859176/ . Obesity

Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat

Martins, J.; Castelo-Branco, M.; Batista, A.; Oliveiros, B.; Santiago, A.R.; Galvão, J.; Fernandes, E.; et al, PLoS ONE. 12. 6. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84455161646&partnerID=MN8TOARS . 10.1371/journal.pone.0029583 . PLoS ONE

Moderate Long-Term modulation of Neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats

Sousa-Ferreira, L.; Garrido, M.; Nascimento-Ferreira, I.; Nobrega, C.; Santos-Carvalho, A.; Álvaro, A.R.; Rosmaninho-Salgado, J.; et al, PLoS ONE. 7. 6. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960672953&partnerID=MN8TOARS . 10.1371/journal.pone.0022333 . PLoS ONE

Regulation of catecholamine release and tyrosine hydroxylase in human adrenal chromaffin cells by interleukin-1ß: Role of neuropeptide y and nitric oxide

Rosmaninho-Salgado, J.; Araújo, I.M.; Álvaro, A.R.; Mendes, A.F.; Ferreira, L.; Grouzmann, E.; Mota, A.; Duarte, E.P.; Cavadas, C., Journal of Neurochemistry. 911 - 922. 3. 109. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-64149092206&partnerID=MN8TOARS . 10.1111/j.1471-4159.2009.06023.x . Journal of Neurochemistry

Neuropeptide y inhibits [Ca2+]i changes in rat retinal neurons through NPY Y1, Y4, and Y5 receptors

Álvaro, A.R.; Rosmaninho-Salgado, J.; Ambrósio, A.F.; Cavadas, C., Journal of Neurochemistry. 1508 - 1515. 5. 109. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-65549153628&partnerID=MN8TOARS . 10.1111/j.1471-4159.2009.06079.x . Journal of Neurochemistry

Stress-induced hypertension and increased sympathetic activity in mice overexpressing neuropeptide y in noradrenergic neurons

Ruohonen, S.T.; Savontaus, E.; Rinne, P.; Rosmaninho-Salgado, J.; Cavadas, C.; Ruskoaho, H.; Koulu, M.; Pesonen, U., Neuroendocrinology. 351 - 360. 3. 89. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349122908&partnerID=MN8TOARS . 10.1159/000188602 . Neuroendocrinology

Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: A role for microglia

Xapelli, S.; Bernardino, L.; Ferreira, R.; Grade, S.; Silva, A.P.; Salgado, J.R.; Cavadas, C.; et al, European Journal of Neuroscience. 2089 - 2102. 8. 27. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42049112780&partnerID=MN8TOARS . 10.1111/j.1460-9568.2008.06172.x . European Journal of Neuroscience

Neuropeptide Y stimulates retinal neural cell proliferation - Involvement of nitric oxide

Álvaro, A.R.; Martins, J.; Araújo, I.M.; Rosmaninho-Salgado, J.; Ambrósio, A.F.; Cavadas, C., Journal of Neurochemistry. 2501 - 2510. 6. 105. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-44649189136&partnerID=MN8TOARS . 10.1111/j.1471-4159.2008.05334.x . Journal of Neurochemistry

Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy

Álvaro, A.R.; Martins, J.; Costa, A.C.; Fernandes, E.; Carvalho, F.; Ambrósio, A.F.; Cavadas, C., Neuroscience. 97 - 105. 1. 152. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-39649105016&partnerID=MN8TOARS . 10.1016/j.neuroscience.2007.12.027 . Neuroscience

Neuropeptide Y regulates catecholamine release evoked by interleukin-1ß in mouse chromaffin cells

Rosmaninho-Salgado, J.; Álvaro, A.R.; Grouzmann, E.; Duarte, E.P.; Cavadas, C., Peptides. 310 - 314. 2. 28. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846606438&partnerID=MN8TOARS . 10.1016/j.peptides.2006.11.015 . Peptides

NPY in rat retina is present in neurons, in endothelial cells and also in microglial and Müller cells

Álvaro, A.R.; Rosmaninho-Salgado, J.; Santiago, A.R.; Martins, J.; Aveleira, C.; Santos, P.F.; Pereira, T.; et al, Neurochemistry International. 757 - 763. 5. 50. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947389655&partnerID=MN8TOARS . 10.1016/j.neuint.2007.01.010 . Neurochemistry International

Intracellular signaling mechanisms mediating catecholamine release upon activation of NPY Y1 receptors in mouse chromaffin cells

Rosmaninho-Salgado, J.; Araújo, I.M.; Álvaro, A.R.; Duarte, E.P.; Cavadas, C., Journal of Neurochemistry. 896 - 903. 3. 103. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35248895279&partnerID=MN8TOARS . 10.1111/j.1471-4159.2007.04899.x . Journal of Neurochemistry

NPY Y<inf>1</inf> receptor is not involved in the hemodynamic response to an acute cold pressor test in mice

Cavadas, C.; Waeber, B.; Pedrazzini, T.; Grand, D.; Aubert, J.-F.; Buclin, T.; Grouzmann, E., Peptides. 315 - 319. 2. 28. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846574363&partnerID=MN8TOARS . 10.1016/j.peptides.2006.11.022 . Peptides

Deletion of the neuropeptide Y (NPY) Y1 receptor gene reveals a regulatory role of NPY on catecholamine synthesis and secretion

Cavadas, C.; Céfai, D.; Rosmaninho-Salgado, J.; Vieira-Coelho, M.A.; Moura, E.; Busso, N.; Pedrazzini, T.; et al, Proceedings of the National Academy of Sciences of the United States of America. 10497 - 10502. 27. 103. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745899338&partnerID=MN8TOARS . 10.1073/pnas.0600913103 . Proceedings of the National Academy of Sciences of the United States of America

Neuropeptide Y expression, localization and cellular transducing effects in HUVEC

Silva, A.P.; Kaufmann, J.E.; Vivancos, C.; Fakan, S.; Cavadas, C.; Shaw, P.; Brunner, H.R.; Vischer, U.; Grouzmann, E., Biology of the Cell. 457 - 467. 6. 97. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-21044442442&partnerID=MN8TOARS . 10.1042/BC20040102 . Biology of the Cell

Up-regulation of neuropeptide Y levels and modulation of glutamate release through neuropeptide Y receptors in the hippocampus of kainate-induced epileptic rats

Silva, A.P.; Xapelli, S.; Pinheiro, P.S.; Ferreira, R.; Lourenço, J.; Cristóvão, A.; Grouzmann, E.; et al, Journal of Neurochemistry. 163 - 170. 1. 93. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-20144388681&partnerID=MN8TOARS . 10.1111/j.1471-4159.2004.03005.x . Journal of Neurochemistry

The putative neuroprotective role of neuropeptide Y in the central nervous system

Silva, A.P.; Xapelli, S.; Grouzmann, E.; Cavadas, C., Current Drug Targets: CNS and Neurological Disorders. 331 - 347. 4. 4. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23144457255&partnerID=MN8TOARS . 10.2174/1568007054546153 . Current Drug Targets: CNS and Neurological Disorders

NPY, NPY receptors, and DPP IV activity are modulated by LPS, TNF-a and IFN-¿ in HUVEC

Silva, A.P.; Cavadas, C.; Baïsse-Agushi, B.; Spertini, O.; Brunner, H.R.; Grouzmann, E., Regulatory Peptides. 71 - 79. 1-3. 116. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242329827&partnerID=MN8TOARS . 10.1016/S0167-0115(03)00191-5 . Regulatory Peptides

Angiotensin II mediates catecholamine and neuropeptide Y secretion in human adrenal chromaffin cells through the AT<inf>1</inf>receptor

Cavadas, C.; Grand, D.; Mosimann, F.; Cotrim, M.D.; Fontes Ribeiro, C.A.; Brunner, H.R.; Grouzmann, E., Regulatory Peptides. 61 - 65. 1-3. 111. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037471366&partnerID=MN8TOARS . 10.1016/S0167-0115(02)00253-7 . Regulatory Peptides

Blood sampling methodology is crucial for precise measurement of plasma catecholamines concentrations in mice

Grouzmann, E.; Cavadas, C.; Grand, D.; Moratel, M.; Aubert, J.-F.; Brunner, H.R.; Mazzolai, L., Pflugers Archiv European Journal of Physiology. 254 - 258. 2. 447. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0842265696&partnerID=MN8TOARS . 10.1007/s00424-003-1140-x . Pflugers Archiv European Journal of Physiology

Neuropeptide Y and its receptors as potential therapeutic drug targets

Silva, A.P.; Cavadas, C.; Grouzmann, E., Clinica Chimica Acta. 3 - 25. 1-2. 326. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036889596&partnerID=MN8TOARS . 10.1016/S0009-8981(02)00301-7 . Clinica Chimica Acta

Loss of dipeptidylpeptidase IV activity in chronic rhinosinusitis contributes to the neurogenic inflammation induced by substance P in the nasal mucosa.

Grouzmann, E.; Monod, M.; Landis, B.; Wilk, S.; Brakch, N.; Nicoucar, K.; Giger, R.; et al, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1132 - 1134. 9. 16. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036634815&partnerID=MN8TOARS . published The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Differential secretion of catecholamine and neuropeptide Y in response to KCl from mice chromaffin cells.

Cavadas C; Silva AP; Cotrim MD; Ribeiro CA; Brunner HR; Grouzmann E, 2002. http://europepmc.org/abstract/med/12438145 . 10.1111/j.1749-6632.2002.tb04489.x .

Catecholamine and Neuropeptide Y Secretion from Human Adrenal Chromaffin Cells

CAVADAS, CLÁUDIA; RIBEIRO, CARLOS ALBERTO FONTES; COTRIM, MARIA DULCE; MOSIMANN, FRANÇOIS; BRUNNER, HANS R.; GROUZMANN, ERIC; Cavadas C; et al, Annals of the New York Academy of Sciences. 332 - 334. 1. 971. 2002. http://dx.doi.org/10.1111/j.1749-6632.2002.tb04488.x . 10.1111/j.1749-6632.2002.tb04488.x . Annals of the New York Academy of Sciences

Dibasic cleavage site is required for sorting to the regulated secretory pathway for both pro- and neuropeptide Y

Brakch, N.; Allemandou, F.; Cavadas, C.; Grouzmann, E.; Brunner, H.R., Journal of Neurochemistry. 1166 - 1175. 6. 81. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036316744&partnerID=MN8TOARS . 10.1046/j.1471-4159.2002.00919.x . Journal of Neurochemistry

NPY regulates catecholamine secretion from human adrenal chromaffin cells

Cavadas, C.; Silva, A.P.; Mosimann, F.; Cotrim, M.D.; Fontes Ribeiro, C.A.; Brunner, H.R.; Grouzmann, E., Journal of Clinical Endocrinology and Metabolism. 5956 - 5963. 12. 86. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035217710&partnerID=MN8TOARS . 10.1210/jc.86.12.5956 . Journal of Clinical Endocrinology and Metabolism

Cardiovascular effects of fentanyl in conscious rats

Baechtold, F.; Cavadas, C.; Gasser, D.; Markert, M.; Grouzmann, E.; Peterson, K.L.; Waeber, B.; Feihl, F., Pflugers Archiv European Journal of Physiology. 155 - 162. 1. 443. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035161078&partnerID=MN8TOARS . 10.1007/s004240100693 . Pflugers Archiv European Journal of Physiology

Interplay between galanin and leptin in the hypothalamic control of feeding via corticotropin-releasing hormone and neuropeptide Y

Bergonzelli, G.E.; Pralong, F.P.; Glauser, M.; Cavadas, C.; Grouzmann, E.; Gaillard, R.C.; Bergonzelli GE; et al, Diabetes. 2666 - 2672. 12. 50. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035656192&partnerID=MN8TOARS . 10.2337/diabetes.50.12.2666 . Diabetes

Disappearance rate of catecholamines, total metanephrines, and neuropeptide Y from the plasma of patients after resection of pheochromocytoma

Grouzmann, E.; Fathi, M.; Gillet, M.; De Torrenté, A.; Cavadas, C.; Brunner, H.; Buclin, T.; et al, Clinical Chemistry. 1075 - 1082. 6 I. 47. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035010093&partnerID=MN8TOARS . Clinical Chemistry

In vitro study of the interaction of Tilia europeae L. aqueous extract with GABA(A) receptors in rat brain

Cavadas, C.; Fontes Ribeiro, C.A.; Santos, M.S.; Cunha, A.P.; Macedo, T.; Caramona, M.M.; Cotrim, M.D., Phytotherapy Research. 17 - 21. 1. 11. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031051651&partnerID=MN8TOARS . 10.1002/(SICI)1099-1573(199702)11:1<17::AID-PTR948>3.0.CO;2-6 . Phytotherapy Research

In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on GABA(A) receptor in rat brain

Cavadas, C.; Araujo, I.; Cotrim, M.D.; Amaral, T.; Cunha, A.P.; Macedo, T.; Fontes Ribeiro, C., Arzneimittel-Forschung/Drug Research. 753 - 755. 7. 45. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029063620&partnerID=MN8TOARS . Arzneimittel-Forschung/Drug Research

All projects

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Information of exclusive responsibility of the researcher 19-05-2024 , from platform CIÊNCIAVITAE.

2024/01 -

GeneT - The Gene Therapy CoE at the Center of Portugal

Project: 101059981 — GeneT — HORIZON-WIDERA-2022-ACCESS-01-two-stage

Researcher

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: European Union

2023/01 - 2023/09

Equal.STEAM Project: Integrated Program to Attract and Retain Girls and Women in Higher Education in Technological and Engineering Areas

POCH-I2-2022-01

Researcher

Universidade de Coimbra

2023/01/01 - 2025

CiNTech - Technological Hub for Innovation, Translation and Industrialization of Complex Injectable Drugs

C644865576-00000005

Researcher

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

2023/09/01 -

NEURODIET - Molecular Mechanisms of Dietary Intervention on Neurodegeneration" - EU Joint Programme Neurodegenerative Disease Research (JPND)

JPND/0002/2022

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2022/02/17 - 2023/02

SCIEVER - Science for Everyone - Sustainability and Inclusion

101061524

Researcher

Universidade de Coimbra Instituto de Investigação Interdisciplinar

2022 - 2023/06/30

Sleep 2 be happy

https://cnc.uc.pt/en/scicomm-projects/sleep-2-be-happy

Researcher

Funders: ResMed Foundation

2021 - 2026

DYNAMIC BRAIN FUNCTION: Towards the Understanding and Treatment of Brain Disorders

952422

Other

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: European Union

2021/01 - 2023/09/01

RI4C2 - Research & Innovation for Cities & Citizens

RI4C2 (P - 101035803)

Principal investigator

Universidade de Coimbra Instituto de Investigação Interdisciplinar

Funders: EU Framework Programme for Research and Innovation Science with and for Society

2021/01 - 2024/12

Perturbação do ritmo circadiano: um alvo para intervenção personalizada nas demências neurodegenerativas

“Perturbação do ritmo circadiano: um alvo para intervenção personalizada nas demências neurodegenerativas”

Co-Principal Investigator (Co-PI)

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Santa Casa da Misericórdia de Lisboa

2021 - 2023

Gender Equal Research @UC EEA Grants (GendER@UC EEA Grant)

GendER@UC

Principal investigator

Universidade de Coimbra

Funders: Comissão para a Cidadania e Igualdade de Género

2018/04 - 2019/03

"SleepApnea ID"

INOV-C Prova de Conceito 2017

Researcher

Funders: Programa Operacional Centro 2020

2018/06/01 - 2021/05/31

FRUITIFY - Use of blueberry juice as a nutraceutical strategy targeting gut dysbiosis to prevent the progression from prediabetes to diabetes

PTDC/SAU-NUT/31712/2017

Researcher

Universidade de Coimbra; Universidade Católica Portuguesa

Funders: Fundação para a Ciência e a Tecnologia

2018/06 - 2021/07

Obstructive Sleep Apnea early diagnosis as a new strategy to delay ageing (noOSA_noAGEING)

POCI-01-0145-FEDER-029002

Co-Principal Investigator (Co-PI)

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2018/07/26 - 2022/07/25

Speed, crash and run: exersomes boost neuroenergetics and mood in mice on speed

PTDC/SAU-DES/30786/2017

Researcher

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2018/07 - 2021/06

NiNjA - New Neuroendocrine Strategy for healthy Aging

Ref: 030167

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation, FCT – Fundação para a Ciência e a Tecnologia

2017/12 - 2020/11

Scientific Leader of PPS4 - Saúde e bem-estar of the Consortium “MobFood - Mobilização de conhecimento científico e tecnológico em resposta aos desafios do mercado agroalimentar.

SI-47-2016-10 - LISBOA-01-0247-FEDER-024524

Principal investigator

Funders: FEDER, COMPETE

2016 - 2017

Ghrelin: a novel therapeutic intervention to rescue the phenotype of Hutchinson-Gilford Progeria Syndrome

PRF2014-53

Researcher

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Progeria Research Foundation

2015/09 - 2017/06

Peripheral NPY reverts HGPS phenotype: a study in human fibroblasts and mouse model

https://www.progeriaresearch.org/grants-funded/#CCavadas

Principal investigator

Funders: Progeria Research Foundation

2014/03 - 2015/02

[Alta Sophia Initiative] Iniciativa Alta Sophia

IAS-IIIUC

Universidade de Coimbra Instituto de Investigação Interdisciplinar

2014/03 - 2015/02

Ageing@Coimbra: A Co-location Centre in the European Knowledge and Innovation Network for Active and Healthy Ageing

Provided by PTCRIS: 135805

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2011/01 - 2013/12

"Quero mais e melhores células! - Células estaminais o que são? Para que servem?"

Projeto 16898

Principal investigator

Funders: COMPETE e Ciência Viva

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/02 - 2012/09

The Neuropeptide Y (NPY) and Dipeptidyl-peptidase IV (DPPIV) as new promising targets on the adipose tissue regulation in obesity

Provided by PTCRIS: 102415

Researcher

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/04 - 2013/09

Life and death of retinal ganglion cells: unmasking the neuromodulatory and neuroprotective roles of Neuropeptide Y

Provided by PTCRIS: 99075

Researcher

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/04 - 2013/07

Effect of caffeine and adenosine A2A receptors on stress response: role of adrenal gland modulation

Provided by PTCRIS: 108110

Principal investigator

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/04 - 2013/07

Adenosine receptors on adrenal medulla regulation: its role on stress response

PTDC/SAU-NEU/108110/2008

Principal investigator

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2010/04 - 2013/07

Caloric restriction increases lifespan: role of neuropeptide Y on autophagy

99082

Principal investigator

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2007/05 - 2010/11

Neuropeptide Y in the retina: Why? What for?

Provided by PTCRIS: 73119

Principal investigator

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2005/09 - 2008/08

Neo-neurogenesis and Microglia in Temporal Lobe Epilesy: Role of Pro-inflammatory Cytokines and Neuropeptide Y in Neuroprotection of New Neurons

Provided by PTCRIS: 58492

Researcher

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2005/04 - 2008/06

Crosstalk between catecholamines and neuropeptide Y in human chromaffin cells

Provided by PTCRIS: 60399

Principal investigator

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2001/10 - 2002/09

Neuropeptide Y function in human adrenal chromaffine cells

65068

Principal investigator

Centro de Neurociências e Biologia Celular, Universidade de Coimbra

Funders: Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung

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