Cláudia Maria Carrudo de Deus

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Information about journal articles, updated at 24-11-2024, from platform CIÊNCIAVITAE.

Investigating the impact of physical activity on mitochondrial function in Parkinson’s disease (PARKEX): Study protocol for A randomized controlled clinical trial

Magaña, Juan Carlos; Deus, Cláudia M.; Baldellou, Laura; Avellanet, Merce; Gea-Rodríguez, Elvira; Enriquez-Calzada, Silvia; Laguna, Ariadna; et al, PLOS ONE. 11. 18. 2023. http://dx.doi.org/10.1371/journal.pone.0293774 . 10.1371/journal.pone.0293774 . published PLOS ONE

Mitochondrial Damage-Associated Molecular Patterns Content in Extracellular Vesicles Promotes Early Inflammation in Neurodegenerative Disorders

Cláudia Deus; Deus, CM; Henrique Tavares; Margarida Beatriz; Sandra Mota; C Lopes, Cells. 2022. https://www.mdpi.com/2073-4409/11/15/2364 . 10.3390/cells11152364 . Cells

Exercise-Boosted Mitochondrial Remodeling in Parkinson’s Disease

Juan Carlos MAGAÑA GALLARDO; Cláudia Deus; Deus, CM; Maria Giné-Garriga; Joel Montane; Pereira SP, Biomedicines. 2022. https://www.mdpi.com/2227-9059/10/12/3228 . 10.3390/biomedicines10123228 . Biomedicines

Modulation of the redox intra-cellular environment as a novel therapeutic strategy for Parkinson’s Disease

Cláudia M. Deus; José Teixeira; Nuno Raimundo; Paolo Tucci; Fernanda Borges; Luciano Saso; Paulo J. Oliveira, Pharmaceutical Research. 2022. under revision Pharmaceutical Research

Mitochondrial and metabolic remodeling in human skin fibroblasts in response to glucose availability

Pinho, Sónia A.; Costa, Cláudio F.; Deus, Cláudia M.; Pinho, Sonia L.C.; Miranda-Santos, Inês; Afonso, Gonçalo; Bagshaw, Olivia; et al, The FEBS Journal. 2022. http://dx.doi.org/10.1111/febs.16413 . 10.1111/febs.16413 . The FEBS Journal

Improving pollutants environmental risk assessment using a multi model toxicity determination with in vitro, bacterial, animal and plant model systems: The case of the herbicide alachlor

Pereira, Susana P.; Santos, Sandra M.A.; Fernandes, Maria A.S.; Deus, Cláudia M.; Martins, João D.; Pedroso de Lima, Maria C.; Vicente, Joaquim A.F.; Videira, Romeu A.; Jurado, Amália S., Environmental Pollution. 286. 2021. http://dx.doi.org/10.1016/j.envpol.2021.117239 . 10.1016/j.envpol.2021.117239 . Environmental Pollution

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al, Redox Biology. 45. 2021. http://dx.doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . Redox Biology

Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain capacity

Serafim, Teresa L.; Cunha-Oliveira, Teresa; Deus, Claudia M.; Sardão, Vilma A.; Cardoso, Ines M.; Yang, Shanshan; Odhiambo, John F.; et al, European Journal of Clinical Investigation. 2020. http://dx.doi.org/10.1111/eci.13375 . 10.1111/eci.13375 . European Journal of Clinical Investigation

Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Pereira, Francisco B.; Raimundo, Nuno; Oliveira, Paulo J., Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 3. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2019.165615 . 10.1016/j.bbadis.2019.165615 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Mitochondria–Lysosome Crosstalk: From Physiology to Neurodegeneration

Deus, Cláudia M.; Yambire, King Faisal; Oliveira, Paulo J.; Raimundo, Nuno, Trends in Molecular Medicine. 71 - 88. 1. 26. 2020. http://dx.doi.org/10.1016/j.molmed.2019.10.009 . 10.1016/j.molmed.2019.10.009 . Trends in Molecular Medicine

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity

Pereira, Susana P; Deus, Cláudia M; Serafim, Teresa L; Cunha-Oliveira, Teresa; Oliveira, Paulo J, Toxicological Sciences. 191 - 204. 1. 164. 2018. http://dx.doi.org/10.1093/toxsci/kfy068 . 10.1093/toxsci/kfy068 . Toxicological Sciences

SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application

Correia-da-Silva, Marta; Rocha, Verónica; Marques, Cláudia; Deus, Cláudia M; Marques-Carvalho, Adriana; Oliveira, Paulo J; Palmeira, Andreia; et al, Journal of Molecular Endocrinology. M27 - M39. 2. 61. 2018. http://dx.doi.org/10.1530/jme-18-0031 . 10.1530/jme-18-0031 . Journal of Molecular Endocrinology

Mitochondria: Targeting mitochondrial reactive oxygen species with mitochondriotropic polyphenolic-based antioxidants

Teixeira, José; Deus, Cláudia M.; Borges, Fernanda; Oliveira, Paulo J., The International Journal of Biochemistry & Cell Biology. 98 - 103. 97. 2018. http://dx.doi.org/10.1016/j.biocel.2018.02.007 . 10.1016/j.biocel.2018.02.007 . The International Journal of Biochemistry & Cell Biology

Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes

Cunha-Oliveira, Teresa; Ferreira, Luciana L.; Coelho, Ana Raquel; Deus, Cláudia M.; Oliveira, Paulo J., Toxicology and Applied Pharmacology. 1 - 13. 348. 2018. http://dx.doi.org/10.1016/j.taap.2018.04.009 . 10.1016/j.taap.2018.04.009 . Toxicology and Applied Pharmacology

Protective Effect of Green Tea (Camellia sinensis (L.) Kuntze) against Prostate Cancer: From In Vitro Data to Algerian Patients

Lassed, Somia; Deus, Cláudia M.; Djebbari, Radja; Zama, Djamila; Oliveira, Paulo J.; Rizvanov, Albert A.; Dahdouh, Abderrezak; Benayache, Fadila; Benayache, Samir, Evidence-Based Complementary and Alternative Medicine. 1 - 12. 2017. 2017. http://dx.doi.org/10.1155/2017/1691568 . 10.1155/2017/1691568 . Evidence-Based Complementary and Alternative Medicine

Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts

Coelho, Ana R.; Martins, Tatiana R.; Couto, Renata; Deus, Cláudia; Pereira, Cláudia V.; Simões, Rui F.; Rizvanov, Albert A.; et al, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2904 - 2923. 11. 1863. 2017. http://dx.doi.org/10.1016/j.bbadis.2017.07.030 . 10.1016/j.bbadis.2017.07.030 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Carvedilol and antioxidant proteins in a type I diabetes animal model

Diogo, Cátia V.; Deus, Cláudia M.; Lebiedzinska-Arciszewska, Magdalena; Wojtala, Aleksandra; Wieckowski, Mariusz R.; Oliveira, Paulo J., European Journal of Clinical Investigation. 19 - 29. 1. 47. 2016. http://dx.doi.org/10.1111/eci.12696 . 10.1111/eci.12696 . European Journal of Clinical Investigation

Diet, Lifestyles, Family History, and Prostate Cancer Incidence in an East Algerian Patient Group

Lassed, Somia; Deus, Cláudia M.; Lourenço, Nuno; Dahdouh, Abderrezak; Rizvanov, Albert A.; Oliveira, Paulo J.; Zama, Djamila, BioMed Research International. 1 - 9. 2016. 2016. http://dx.doi.org/10.1155/2016/5730569 . 10.1155/2016/5730569 . BioMed Research International

Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells

Deus, Cláudia M.; Serafim, Teresa L.; Magalhães-Novais, Silvia; Vilaça, Andreia; Moreira, Ana C.; Sardão, Vilma A.; Cardoso, Susana M.; Oliveira, Paulo J., Archives of Toxicology. 1261 - 1278. 3. 91. 2016. http://dx.doi.org/10.1007/s00204-016-1784-x . 10.1007/s00204-016-1784-x . Archives of Toxicology

Measuring p66Shc Signaling Pathway Activation and Mitochondrial Translocation in Cultured Cells

Wieckowski, Mariusz R.; Deus, Cláudia M.; Couto, Renata; Oparka, Monika; Lebiedzinska-Arciszewska, Magdalena; Duszynski, Jerzy; Oliveira, Paulo J., Current Protocols in Toxicology. 25.6.1 - 25.6.21. 1. 66. 2015. http://dx.doi.org/10.1002/0471140856.tx2506s66 . 10.1002/0471140856.tx2506s66 . Current Protocols in Toxicology

Shutting Down the Furnace: Preferential Killing of Cancer Cells with Mitochondrial-Targeting Molecules

Deus, Cláudia; Santos, Gabriela; Loureiro, Rute; Vega-Naredo, Ignacio; Faneca, Henrique; Oliveira, Paulo, Current Medicinal Chemistry. 2438 - 2457. 20. 22. 2015. http://dx.doi.org/10.2174/0929867322666150209155957 . 10.2174/0929867322666150209155957 . Current Medicinal Chemistry

Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts

Deus, Cláudia M.; Zehowski, Cheryl; Nordgren, Kendra; Wallace, Kendall B.; Skildum, Andrew; Oliveira, Paulo J., Toxicology. 1 - 11. 334. 2015. http://dx.doi.org/10.1016/j.tox.2015.05.001 . 10.1016/j.tox.2015.05.001 . Toxicology

Targeting mitochondrial function for the treatment of breast cancer

Deus, Cláudia M; Coelho, Ana R; Serafim, Teresa L; Oliveira, Paulo J; Deus, Cláudia, Future Medicinal Chemistry. 1499 - 1513. 13. 6. 2014. http://dx.doi.org/10.4155/fmc.14.100 . 10.4155/fmc.14.100 . Future Medicinal Chemistry

All projects

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Information of exclusive responsibility of the researcher 24-11-2024 , from platform CIÊNCIAVITAE.

2024 - 2027

Small extracellular vesicles-based Nrf2 mRNA delivery as a therapeutic approach for Parkinson’s Disease

n/a

Principal investigator

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2023/07/27 -

The Effects on Physical Activity on Mitochondrial Function in Skin Fibroblasts in Patients With Parkinson's Disease. (PARKEX Clinical Trial))

NCT05963425

Post-doc

2023 - 2023

mitoMOVE4PD: Mitochondrial and metabolic remodeling induced by physical activity in fibroblasts from Parkinson's Disease patients (not contracted for bureaucratic reasons)

2022.01232.PTDC

Principal investigator

Fundação para a Ciência e a Tecnologia

2022/10/26 -

LightImplant - Fabrication of light responsive and multifuntional dental implant for the treatment of peri-implant diseases

PTDC/CTM-CTM/1719/2021

Post-doc

Funders: Fundação para a Ciência e a Tecnologia

2022/01/03 -

Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis

EXPL/BTM-TEC/1407/2021

Researcher

Funders: Fundação para a Ciência e a Tecnologia

2022/01/01 - 2022/06/04

EXOmirHD: iPS cells-derived exosomes - impact on mitochondrial (dys)function in Huntington's disease and potential nanodelivery system for microRNA-based therapeutics

PTDC/BTM-TEC/29621/2017

Post-doc

Funders: Fundação para a Ciência e a Tecnologia

2021/04/01 - 2021/12/05

MitoScreening: Development and validation of innovative screening methods for mitochondrial health modulators

PTDC/BTM-SAL/29297/2017

Researcher

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021/06/01

Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype

PTDC/MED-FAR/29391/2017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2017 - 2020

MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria Pathophysiology

PTDC/DTP-FTO/2433/2014

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2015 - 2016

An Epigenetic Engineering Approach to Reverse the Parkinson Disease (PD) Cell State

CPD0028001

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2013/05/15 - 2015/04/30

Pathophysiology of persistent cardiac toxicity of Doxorubicin: A link between Mitochondria and Epigenetic

PTDC/DTP-FTO/1180/2012

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012/06/01 - 2013/03/30

Opening Pandora’s Box for Active Anti-Breast Cancer Therapy – Role of Selective Targeting to Mitochondria

PTDC/QUI-QUI/101409/2008

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

2011/03/01 - 2013

Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction

info:eu-repo/grantAgreement/FCT/5876-PPCDTI/110952/PT

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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