Diana Duarte Lobo

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PhD Student

Publications

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Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.

miRNA mediated knockdown of ATXN3 alleviates molecular disease hallmarks in a mouse model for Spinocerebellar ataxia type 3

Nobre, Rui Jorge; Lobo, Diana Duarte; Henriques, Carina; Pereira de Almeida, Luis Fernando Morgado, Nucleic Acid Therapeutics. 2021. accepted Nucleic Acid Therapeutics

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease

Vasconcelos-Ferreira, Ana; Martins, Inês Morgado; Lobo, Diana; Pereira, Dina; Lopes, Miguel M.; Faro, Rosário; Lopes, Sara M.; et al, Molecular Therapy. 2021. http://dx.doi.org/10.1016/j.ymthe.2021.07.012 . 10.1016/j.ymthe.2021.07.012 . published Molecular Therapy

The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples

Duarte Lobo, Diana; Nobre, Rui Jorge; Oliveira Miranda, Catarina; Pereira, Dina; Castelhano, João; Sereno, José; Koeppen, Arnulf; Castelo-Branco, Miguel; Pereira de Almeida, Luís, Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-00955-0 . 10.1186/s40478-020-00955-0 . published Acta Neuropathologica Communications

Antisense oligonucleotide therapeutics in neurodegenerative diseases: the case of polyglutamine disorders

Silva, Ana C; Lobo, Diana D; Martins, Inês M; Lopes, Sara M; Henriques, Carina; Duarte, Sónia P; Dodart, Jean-Cosme; Nobre, Rui Jorge; Pereira de Almeida, Luis, Brain. 407 - 429. 2. 143. 2019. http://dx.doi.org/10.1093/brain/awz328 . 10.1093/brain/awz328 . Brain

All projects

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Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.

2020/03 -

Laboratório de Análises Clínicas da Universidade de Coimbra - SARS-Cov2 Detection

LAC-UC

Other

Universidade de Coimbra

2020/06 - 2020/08

Validação expedita e Fabrico em larga escala de um dispositivo de sopro para colheita com inativação de amostras para deteção do SARS-CoV-2

269_596884125

Researcher

Universidade de Coimbra; Universidade de Coimbra Instituto de Investigação Interdisciplinar; ViraVector - Unidade de produção vectores virais para transferência de genes

Funders: Fundação para a Ciência e a Tecnologia; Agency for Clinical Research and Biomedical Innovation (AICIB)

2019/02/20 - 2019/09/30

Targeting ATXN3 for the treatment of Spinocerebellar Ataxia 3 (SCA3) using AAV5 and an artificial microRNA

NA

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: uniQure NV

2019/12 - 2020/01

A Therapeutic Strategy in Machado-Joseph Disease

CPD0020A01

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Blade Therapeutics

2018/09 -

Targeting mutant ATXN3 for the treatment of Spinocerebellar Ataxia 3 (SCA3)

CSD3#IV0020

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Wave Life Sciences USA, Inc.

Funders: Wave Life Sciences USA, Inc.

2018/05/11 - 2020/12/31

BrainHealth 2020: Deteção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias

SAICT 000008 BrainHealth 2020

Research Fellow

CNC.IBILI

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