Eugenia Carvalho

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Center for Neuroscience and Cell Biology, University of Coimbra


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Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.

Redox Imbalance and Methylation Disturbances in Early Childhood Obesity

Pedro Barbosa; Stepan Melnyk; Sirish C. Bennuri; Leanna Delhey; Andreia Reis; Gabriela R. Moura; Elisabet Børsheim; et al, Oxidative Medicine and Cellular Longevity. 2021. . 10.1155/2021/2207125 . Oxidative Medicine and Cellular Longevity

Stress-Reducing Psychological Interventions as Adjuvant Therapies for Diabetic Chronic Wounds

Isadora Pombeiro; João Moura; Maria Graça Pereira; Eugénia Carvalho, Current Diabetes Reviews. 2021. . 10.2174/1573399817666210806112813 . Current Diabetes Reviews

Short-Term Increased Physical Activity During Early Life Affects High-Fat Diet–Induced Bone Loss in Young Adult Mice

Chen, Jin-Ran; Lazarenko, Oxana P; Carvalho, Eugenia; Blackburn, Michael L; Shankar, Kartik; Wankhade, Umesh D; Børsheim, Elisabet, JBMR Plus. 7. 5. 2021. . 10.1002/jbm4.10508 . JBMR Plus

Dietary supplementation with sulforaphane ameliorates skin aging through activation of the Keap1-Nrf2 pathway

Petkovic, Marija; Leal, Ermelindo C; Alves, Ines; Bose, Chanda; Palade, Philip T; Singh, Preeti; Awasthi, Sanjay; et al, The Journal of Nutritional Biochemistry. 2021. . 10.1016/j.jnutbio.2021.108817 . The Journal of Nutritional Biochemistry

mTOR Signaling as a Regulator of Hematopoietic Stem Cell Fate

Hélia Fernandes; João Moura; Eugénia Carvalho; H. Fernandes; João Moura Alves; Carvalho, Eugenia, Stem Cell Reviews and Reports. 2021. . 10.1007/s12015-021-10131-z . accepted Stem Cell Reviews and Reports

Improved diabetic wound healing by bovine lactoferricin is associated with relevant changes in the skin immune response and microbiota

Mouritzen MV; Petkovic, Marija; Qvist K; Poulsen SS; Alarico S; Leal, EC; Dalgaard LT; et al, Molecular Therapy - Methods & Clinical Development. 2021. accepted Molecular Therapy - Methods & Clinical Development

Drug-induced metabolic alterations in adipose tissue - with an emphasis in epicardial

Pinho, Aryane Cruz Oliveira; Ana Burgeiro; Maria João Rodrigues Pereira (1513-EB2F-0D7F); Carvalho, Eugenia, Annals of the Brazilian Academy of Sciences. 2021. accepted Annals of the Brazilian Academy of Sciences

Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk

Carvalho, Eugenia; Adams, Sean H.; Børsheim, Elisabet; Blackburn, Michael L.; Ono-Moore, Kikumi D.; Cotter, Matthew; Bowlin, Anne K.; Yeruva, Laxmi, BMC Nutrition. 1. 6. 2020. . 10.1186/s40795-020-00338-7 . BMC Nutrition

Transient gain of function of cannabinoid CB1 receptors in the control of frontocortical glucose consumption in a rat model of Type-1 diabetes

Pedro, Joana Reis; Moura, Liane I.F.; Valério-Fernandes, Ângela; Baptista, Filipa I.; Gaspar, Joana M.; Pinheiro, Bárbara S.; Lemos, Cristina; et al, Brain Research Bulletin. 106 - 115. 161. 2020. . 10.1016/j.brainresbull.2020.05.004 . Brain Research Bulletin

Protein tyrosine phosphatase 1B inhibition as a potential therapeutic target for chronic wounds in diabetes

Figueiredo, Ana; Leal, Ermelindo C.; Carvalho, Eugénia, Pharmacological Research. 159. 2020. . 10.1016/j.phrs.2020.104977 . Pharmacological Research

Lack of lymphocytes impairs macrophage polarization and angiogenesis in diabetic wound healing

Seraphim, Patricia M.; Leal, Ermelindo C.; Moura, João; Gonçalves, Pedro; Gonçalves, Jenifer P.; Carvalho, Eugénia, Life Sciences. 254. 2020. . 10.1016/j.lfs.2020.117813 . Life Sciences

Mechanistic Actions of microRNAs in Diabetic Wound Healing

Petkovic, Marija; Sørensen, Anja Elaine; Leal, Ermelindo Carreira; Carvalho, Eugenia; Dalgaard, Louise Torp, Cells. 10. 9. 2020. . 10.3390/cells9102228 . Cells

Sulforaphane prevents age-associated cardiac and muscular dysfunction through Nrf2 signaling

Bose, Chhanda; Alves, Ines; Singh, Preeti; Palade, Philip T.; Carvalho, Eugenia; Børsheim, Elisabet; Jun, Se-Ran; et al, Aging Cell. 11. 19. 2020. . 10.1111/acel.13261 . Aging Cell

Multi-Omic Analysis Reveals Different Effects of Sulforaphane on the Microbiome and Metabolome in Old Compared to Young Mice

Jun, Se-Ran; Cheema, Amrita; Bose, Chhanda; Boerma, Marjan; Palade, Philip T.; Carvalho, Eugenia; Awasthi, Sanjay; Singh, Sharda P., Microorganisms. 10. 8. 2020. . 10.3390/microorganisms8101500 . Microorganisms

Chronic insulinopenia/hyperglycemia decrease cannabinoid CB1 receptor density and impair glucose uptake in the mouse forebrain

Liane I.F. Moura; Cristina Lemos; Catherine Ledent; Eugénia Carvalho; Attila Köfalvi, Brain Research Bulletin. 2019. . 10.1016/j.brainresbull.2019.01.024 . Brain Research Bulletin

A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women

Rose, Shannon; Carvalho, Eugenia; Diaz, Eva C.; Cotter, Matthew; Bennuri, Sirish C.; Azhar, Gohar; Frye, Richard E.; Adams, Sean H.; Børsheim, Elisabet, American Journal of Physiology-Endocrinology and Metabolism. E503 - E512. 3. 317. 2019. . 10.1152/ajpendo.00084.2019 . American Journal of Physiology-Endocrinology and Metabolism

Immune aging in diabetes and its implications in wound healing

Moura, J.; Madureira, P.; Leal, E.C.; Fonseca, A.C.; Carvalho, E., Clinical Immunology. 43 - 54. 200. 2019. . 10.1016/j.clim.2019.02.002 . Clinical Immunology

The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration

Henriques-Antunes, Helena; Cardoso, Renato M. S.; Zonari, Alessandra; Correia, Joana; Leal, Ermelindo C.; Jiménez-Balsa, Adrián; Lino, Miguel M.; et al, ACS Nano. 8694 - 8707. 8. 13. 2019. . 10.1021/acsnano.9b00376 . ACS Nano

Establishing a Link Between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model

Carvalho, Eugenia, Cellular Physiology and Biochemistry. 503 - 516. 3. 52. 2019. . 10.33594/000000036 . Cellular Physiology and Biochemistry

microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation

Moura, João; Sørensen, Anja; Leal, Ermelindo C.; Svendsen, Rikke; Carvalho, Lina; Willemoes, Rie Juul; Jørgensen, Per Trolle; et al, Scientific Reports. 1. 9. 2019. . 10.1038/s41598-019-42309-4 . Scientific Reports

Imbalance in T-cell differentiation as a biomarker of chronic diabetic foot ulceration

Moura, João; Rodrigues, João; Gonçalves, Marta; Amaral, Cláudia; Lima, Margarida; Carvalho, Eugénia, Cellular & Molecular Immunology. 2019. . 10.1038/s41423-019-0233-1 . Cellular & Molecular Immunology

Calcineurin is an important factor involved in glucose uptake in human adipocytes

Ana Catarina R. G. Fonseca; Eugénia Carvalho; Jan W. Eriksson; Maria J. Pereira, Molecular and Cellular Biochemistry. 157 - 168. 1-2. 445. 2018. . 10.1007/s11010-017-3261-0 . Molecular and Cellular Biochemistry

Neurotensin, substance P, and insulin enhance cell migration

Michelle V. Mouritzen; Sali Abourayale; Rooshanie Ejaz; Christine B. Ardon; Eugenia Carvalho; Louise T. Dalgaard; Martin Roursgaard; Håvard Jenssen, Journal of Peptide Science. e3093 - e3093. 7. 24. 2018. . 10.1002/psc.3093 . Journal of Peptide Science

Wanted: MicroRNAs to the aid of the diabetic foot

Louise T. Dalgaard; Eugenia Carvalho, Trends in Cardiovascular Medicine. 2018. . 10.1016/j.tcm.2018.09.002 . Trends in Cardiovascular Medicine

Skeletal Muscle Acute and Chronic Metabolic Response to Essential Amino Acid Supplementation in Hypertriglyceridemic Older Adults

Marquis, Bryce J; Hurren, Nicholas M; Carvalho, Eugenia; Kim, Il-Young; Schutzler, Scott; Azhar, Gohar; Wolfe, Robert R; Børsheim, Elisabet, Current Developments in Nutrition. 11. 1. 2017. . 10.3945/cdn.117.002071 . Current Developments in Nutrition

Microbiota of Chronic Diabetic Wounds: Ecology, Impact, and Potential for Innovative Treatment Strategies.

Pereira SG; Moura J; Carvalho E; Empadinhas N, Frontiers in microbiology. 2017. . 10.3389/fmicb.2017.01791 . Frontiers in microbiology

Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet.

Burgeiro A; Cerqueira MG; Varela-Rodríguez BM; Nunes S; Neto P; Pereira FC; Reis F; Carvalho E, Nutrients. 2017. . 10.3390/nu9060638 . Nutrients

Impaired T-cell differentiation in diabetic foot ulceration.

Moura J; Rodrigues J; Gonçalves M; Amaral C; Lima M; Carvalho E, Cellular & molecular immunology. 2017. . 10.1038/cmi.2015.116 . Cellular & molecular immunology

Reply to Katlandur, Ozbek, and Keser.

Carvalho E; Lopaschuk GD; Børsheim E; Burgeiro A, American journal of physiology. Endocrinology and metabolism. 2016. . 10.1152/ajpendo.00113.2016 . American journal of physiology. Endocrinology and metabolism

Mast Cells Regulate Wound Healing in Diabetes.

Tellechea A; Leal EC; Kafanas A; Auster ME; Kuchibhotla S; Ostrovsky Y; Tecilazich F; et al, Diabetes. 2016. . 10.2337/db15-0340 . Diabetes

Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.

García-Casarrubios E; de Moura C; Arroba AI; Pescador N; Calderon-Dominguez M; Garcia L; Herrero L; et al, Biochimica et biophysica acta. 2016. . 10.1016/j.bbalip.2016.09.016 . Biochimica et biophysica acta

Effects of insulin on the skin: possible healing benefits for diabetic foot ulcers.

Emanuelli T; Burgeiro A; Carvalho E, Archives of dermatological research. 2016. . 10.1007/s00403-016-1686-z . Archives of dermatological research

Glucose uptake and lipid metabolism are impaired in epicardial adipose tissue from heart failure patients with or without diabetes.

Burgeiro A; Fuhrmann A; Cherian S; Espinoza D; Jarak I; Carvalho RA; Loureiro M; et al, American journal of physiology. Endocrinology and metabolism. 2016. . 10.1152/ajpendo.00384.2015 . American journal of physiology. Endocrinology and metabolism

The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A "Me Too" or "the Special One" Antidiabetic Class?

Godinho R; Mega C; Teixeira-de-Lemos E; Carvalho E; Teixeira F; Fernandes R; Reis F, Journal of diabetes research. 2015. . 10.1155/2015/806979 . Journal of diabetes research

Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype

Carvalho, Eugenia, Am J Pathol. 2015. . Am J Pathol

Cyclosporine a-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat

Sereno, J.; Vala, H.; Nunes, S.; Rocha-Pereira, P.; Carvalho, E.; Alves, R.; Teixeira, F.; Reis, F., Journal of Physiology and Pharmacology. 285 - 299. 2. 66. 2015. . Journal of Physiology and Pharmacology

Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic mice

Moura, L.I.F.; Dias, A.M.A.; Suesca, E.; Casadiegos, S.; Leal, E.C.; Fontanilla, M.R.; Carvalho, L.; de Sousa, H.C.; Carvalho, E., Biochimica et Biophysica Acta - Molecular Basis of Disease. 32 - 43. 1. 1842. 2014. . 10.1016/j.bbadis.2013.10.009 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Chitosan-based dressings loaded with neurotensin - An efficient strategy to improve early diabetic wound healing

Moura, L.I.F.; Dias, A.M.A.; Leal, E.C.; Carvalho, L.; De Sousa, H.C.; Carvalho, E., Acta Biomaterialia. 843 - 857. 2. 10. 2014. . 10.1016/j.actbio.2013.09.040 . Acta Biomaterialia

Molecular mechanisms underlying the effects of cyclosporin A and sirolimus on glucose and lipid metabolism in liver, skeletal muscle and adipose tissue in an in vivo rat model

Fuhrmann, A.; Lopes, P.; Sereno, J.; Pedro, J.; Espinoza, D.O.; Pereira, M.J.; Reis, F.; Eriksson, J.W.; Carvalho, E., Biochemical Pharmacology. 216 - 228. 2. 88. 2014. . 10.1016/j.bcp.2014.01.020 . Biochemical Pharmacology

Cyclosporine A and tacrolimus reduce the amount of GLUT4 at the cell surface in human adipocytes: Increased endocytosis as a potential mechanism for the diabetogenic effects of immunosuppressive agents

Pereira, M.J.; Palming, J.; Rizell, M.; Aureliano, M.; Carvalho, E.; Svensson, M.K.; Eriksson, J.W., Journal of Clinical Endocrinology and Metabolism. E1885 - E1894. 10. 99. 2014. . 10.1210/jc.2014-1266 . Journal of Clinical Endocrinology and Metabolism

Cyclosporine A enhances gluconeogenesis while sirolimus impairs insulin signaling in peripheral tissues after 3 weeks of treatment

Lopes, P.C.; Fuhrmann, A.; Carvalho, F.; Sereno, J.; Santos, M.R.; Pereira, M.J.; Eriksson, J.W.; Reis, F.; Carvalho, E., Biochemical Pharmacology. 61 - 73. 1. 91. 2014. . 10.1016/j.bcp.2014.06.014 . Biochemical Pharmacology

Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model

Sereno, J.; Rodrigues-Santos, P.; Vala, H.; Rocha-Pereira, P.; Alves, R.; Fernandes, J.; Santos-Silva, A.; et al, International Journal of Molecular Sciences. 8979 - 8997. 5. 15. 2014. . 10.3390/ijms15058979 . International Journal of Molecular Sciences

The role of micrornas in diabetic complications—special emphasis on wound healing

Moura, J.; Børsheim, E.; Carvalho, E., Genes. 926 - 956. 4. 5. 2014. . 10.3390/genes5040926 . Genes

Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats

Lopes, P.C.; Fuhrmann, A.; Sereno, J.; Espinoza, D.O.; Pereira, M.J.; Eriksson, J.W.; Reis, F.; Carvalho, E., Metabolism: Clinical and Experimental. 702 - 715. 5. 63. 2014. . 10.1016/j.metabol.2014.02.004 . Metabolism: Clinical and Experimental

Neurotensin decreases the proinflammatory status of human skin fibroblasts and increases epidermal growth factor expression

Da Silva, L.P.; Neves, B.M.; Moura, L.; Cruz, M.T.; Carvalho, E., International Journal of Inflammation. 2014. 2014. . 10.1155/2014/248240 . International Journal of Inflammation

The effect of neurotensin in human keratinocytes - implication on impaired wound healing in diabetes

Moura, L.I.; Cruz, M.T.; Carvalho, E., Experimental Biology and Medicine. 6 - 12. 1. 239. 2014. . 10.1177/1535370213510665 . Experimental Biology and Medicine

Role of endothelial progenitor cells and inflammatory cytokines in healing of diabetic foot ulcers

Tecilazich, F.; Dinh, T.; Pradhan-Nabzdyk, L.; Leal, E.; Tellechea, A.; Kafanas, A.; Gnardellis, C.; et al, PLoS ONE. 12. 8. 2013. . 10.1371/journal.pone.0083314 . PLoS ONE

Recent advances on the development of wound dressings for diabetic foot ulcer treatment - A review

Moura, L.I.F.; Dias, A.M.A.; Carvalho, E.; De Sousa, H.C., Acta Biomaterialia. 7093 - 7114. 7. 9. 2013. . 10.1016/j.actbio.2013.03.033 . Acta Biomaterialia

Serum and renal tissue markers of nephropathy in rats under immunosuppressive therapy: Cyclosporine versus sirolimus

Sereno, J.; Parada, B.; Rodrigues-Santos, P.; Lopes, P.C.; Carvalho, E.; Vala, H.; Teixeira-Lemos, E.; et al, Transplantation Proceedings. 1149 - 1156. 3. 45. 2013. . 10.1016/j.transproceed.2013.02.085 . Transplantation Proceedings

The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue

Pereira, M.J.; Palming, J.; Rizell, M.; Aureliano, M.; Carvalho, E.; Svensson, M.K.; Eriksson, J.W., Molecular and Cellular Endocrinology. 260 - 269. 2. 365. 2013. . 10.1016/j.mce.2012.10.030 . Molecular and Cellular Endocrinology

Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions

Moura, L.I.F.; Silva, L.; Leal, E.C.; Tellechea, A.; Cruz, M.T.; Carvalho, E., BioMed Research International. 2013. 2013. . 10.1155/2013/941764 . BioMed Research International

Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: Potential benefits for wound healing

Moura, J.; Da Silva, L.; Cruz, M.T.; Carvalho, E., Archives of Dermatological Research. 557 - 569. 7. 305. 2013. . 10.1007/s00403-013-1381-2 . Archives of Dermatological Research

Increased skin inflammation and blood vessel density in human and experimental diabetes

Tellechea, A.; Kafanas, A.; Leal, E.C.; Tecilazich, F.; Kuchibhotla, S.; Auster, M.E.; Kontoes, I.; et al, International Journal of Lower Extremity Wounds. 4 - 11. 1. 12. 2013. . 10.1177/1534734612474303 . International Journal of Lower Extremity Wounds

Early cardiac changes in a rat model of prediabetes: Brain natriuretic peptide overexpression seems to be the best marker

Nunes, S.; Soares, E.; Fernandes, J.; Viana, S.; Carvalho, E.; Pereira, F.C.; Reis, F., Cardiovascular Diabetology. 1. 12. 2013. . 10.1186/1475-2840-12-44 . Cardiovascular Diabetology

Spatial memory impairments in a prediabetic rat model

Soares, E.; Prediger, R.D.; Nunes, S.; Castro, A.A.; Viana, S.D.; Lemos, C.; De Souza, C.M.; et al, Neuroscience. 565 - 577. 250. 2013. . 10.1016/j.neuroscience.2013.07.055 . Neuroscience

Effects of cyclosporine and sirolimus on insulin-stimulated glucose transport and glucose tolerance in a rat model

Lopes, P.; Fuhrmann, A.; Sereno, J.; Pereira, M.J.; Nunes, P.; Pedro, J.; Melão, A.; Reis, F.; Carvalho, E., Transplantation Proceedings. 1142 - 1148. 3. 45. 2013. . 10.1016/j.transproceed.2013.02.009 . Transplantation Proceedings

MTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

Pereira, M.J.; Palming, J.; Rizell, M.; Aureliano, M.; Carvalho, E.; Svensson, M.K.; Eriksson, J.W., Molecular and Cellular Endocrinology. 96 - 105. 1. 355. 2012. . 10.1016/j.mce.2012.01.024 . Molecular and Cellular Endocrinology

Cardiorenal benefits of early versus late cyclosporine to sirolimus conversion in a rat model

Sereno, J.; Romão, A.M.; Parada, B.; Lopes, P.; Carvalho, E.; Teixeira, F.; Reis, F., Journal of Pharmacology and Pharmacotherapeutics. 143 - 148. 2. 3. 2012. . 10.4103/0976-500X.95513 . Journal of Pharmacology and Pharmacotherapeutics

Cellular cross-talk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease

Cherian, S.; Lopaschuk, G.D.; Carvalho, E., American Journal of Physiology - Endocrinology and Metabolism. 8. 303. 2012. . 10.1152/ajpendo.00061.2012 . American Journal of Physiology - Endocrinology and Metabolism

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells

Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L., PLoS ONE. 1. 6. 2011. . 10.1371/journal.pone.0016114 . PLoS ONE

Neurotensin downregulates the pro-inflammatory properties of skin dendritic cells and increases epidermal growth factor expression

da Silva, L.; Neves, B.M.; Moura, L.; Cruz, M.T.; Carvalho, E., Biochimica et Biophysica Acta - Molecular Cell Research. 1863 - 1871. 10. 1813. 2011. . 10.1016/j.bbamcr.2011.06.018 . Biochimica et Biophysica Acta - Molecular Cell Research

Study of the antidiabetic capacity of the VO(dmpp)2 complex

Passadouro, M.; Metelo, A.M.; Melão, A.S.; Pedro, J.R.; Faneca, H.; Carvalho, E.; Castro, M.M.C.A., Journal of Inorganic Biochemistry. 987 - 992. 9. 104. 2010. . 10.1016/j.jinorgbio.2010.05.004 . Journal of Inorganic Biochemistry

Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing

Da Silva, L.; Carvalho, E.; Cruz, M.T., Expert Opinion on Biological Therapy. 1427 - 1439. 10. 10. 2010. . 10.1517/14712598.2010.515207 . Expert Opinion on Biological Therapy

Effects of decavanadate and insulin enhancing vanadium compounds on glucose uptake in isolated rat adipocytes

Pereira, M.J.; Carvalho, E.; Eriksson, J.W.; Crans, D.C.; Aureliano, M., Journal of Inorganic Biochemistry. 1687 - 1692. 12. 103. 2009. . 10.1016/j.jinorgbio.2009.09.015 . Journal of Inorganic Biochemistry

Elimination of glucose contamination from adipocyte glycogen extracts

Nunes, P.M.; Carvalho, E.; Jones, J.G., Carbohydrate Research. 1486 - 1489. 9. 343. 2008. . 10.1016/j.carres.2008.04.004 . Carbohydrate Research

Substance P as a Novel Anti-obesity Target

Karagiannides, I.; Torres, D.; Tseng, Y.; Bowe, C.; Carvalho, E.; Espinoza, D.; Pothoulakis, C.; Kokkotou, E., Gastroenterology. 3. 134. 2008. . 10.1053/j.gastro.2007.12.032 . Gastroenterology

Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle

Carvalho, E.; Kotani, K.; Peroni, O.D.; Kahn, B.B., American Journal of Physiology - Endocrinology and Metabolism. 4 52-4. 289. 2005. . 10.1152/ajpendo.00116.2005 . American Journal of Physiology - Endocrinology and Metabolism

GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulin-responsive aminopeptidase

Carvalho, E.; Schellhorn, S.E.; Zabolotny, J.M.; Martin, S.; Tozzo, E.; Peroni, O.D.; Houseknecht, K.L.; et al, Journal of Biological Chemistry. 21598 - 21605. 20. 279. 2004. . 10.1074/jbc.M312269200 . Journal of Biological Chemistry

Evidence of impaired adipogenesis in insulin resistance

Yang, X.; Jansson, P.-A.; Nagaev, I.; Jack, M.M.; Carvalho, E.; Sunnerhagen, K.S.; Cam, M.C.; Cushman, S.W.; Smith, U., Biochemical and Biophysical Research Communications. 1045 - 1051. 4. 317. 2004. . 10.1016/j.bbrc.2004.03.152 . Biochemical and Biophysical Research Communications

A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin

Jansson, P.-A.; Pellmé, F.; Hammarstedt, A.; Sandqvist, M.; Brekke, H.; Caidahl, K.; Forsberg, M.; et al, FASEB Journal. 1434 - 1440. 11. 17. 2003. . 10.1096/fj.02-1132com . FASEB Journal

Insulin resistance with low cellular IRS-1 expression is also associated with low GLUT4 expression and impaired insulin-stimulated glucose transport.

Carvalho, E.; Jansson, P.A.; Nagaev, I.; Wenthzel, A.M.; Smith, U., The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1101 - 1103. 6. 15. 2001. . The FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Insulin resistance in fat cells from obese Zucker rats - Evidence for an impaired activation and translocation of protein kinase B and glucose transporter 4

Carvalho, E.; Rondinone, C.; Smith, U., Molecular and Cellular Biochemistry. 7 - 16. 1-2. 206. 2000. . Molecular and Cellular Biochemistry

PKB inhibition prevents the stimulatory effect of insulin on glucose transport and protein translocation but not the antilipolytic effect in rat adipocytes

Smith, U.; Carvalho, E.; Mosialou, E.; Beguinot, F.; Formisano, P.; Rondinone, C., Biochemical and Biophysical Research Communications. 315 - 320. 2. 268. 2000. . 10.1006/bbrc.2000.2145 . Biochemical and Biophysical Research Communications

Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor

Rondinone, C.M.; Carvalho, E.; Rahn, T.; Manganiello, V.C.; Degerman, E.; Smith, U.P., Journal of Biological Chemistry. 10093 - 10098. 14. 275. 2000. . 10.1074/jbc.275.14.10093 . Journal of Biological Chemistry

Impaired phosphorylation and insulin-stimulated translocation to the plasma membrane of protein kinase B/Akt in adipocytes from type II diabetic subjects

Carvalho, E.; Eliasson, B.; Wesslau, C.; Smith, U., Diabetologia. 1107 - 1115. 9. 43. 2000. . 10.1007/s001250051501 . Diabetologia

Low cellular IRS 1 gene and protein expression predict insulin resistance and NIDDM

Carvalho, E.; Jansson, P.-A.; Axelsen, M.; Eriksson, J.W.; Huang, X.; Groop, L.; Rondinone, C.; Sjöström, L.; Smith, U., FASEB Journal. 2173 - 2178. 15. 13. 1999. . FASEB Journal

Impaired glucose transport and protein kinase B activation by insulin, but not okadaic acid, in adipocytes from subjects with Type II diabetes mellitus

Rondinone, C.M.; Carvalho, E.; Wesslau, C.; Smith, U.P., Diabetologia. 819 - 825. 7. 42. 1999. . 10.1007/s001250051232 . Diabetologia

Electron paramagnetic resonance studies of cobalt-substituted angiotensin I-converting enzyme

Carvalho, E.; Aasa, R.; Göthe, P.-O., Journal of Inorganic Biochemistry. 147 - 153. 2. 62. 1996. . 10.1016/0162-0134(95)00143-3 . Journal of Inorganic Biochemistry

Effect of inhibitors on the coordination geometries of cadmium at the metal sites in angiotensin-I-converting enzyme

Carvalho, E.; Gothe, P.O.; Bauer, R.; Danielsen, E.; Hemmingsen, L., European Journal of Biochemistry. 780 - 785. 3. 234. 1995. . European Journal of Biochemistry

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Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.

2019/01 - 2019/12

Role of Regulatory T-cells in Obesity-Linked Insulin Resistance and Diabetes

COM Sturgis project grant

Funders: N/A

2019/01 - 2020/12

MicroRNAs as markers of disturbed adipose tissue function and inflammation - a potential mechanism for diabetes development in obesity

COM Child Health project grant


University of Arkansas for Medical Sciences

Funders: N/A

2019/03 - 2020/12

CD20+ T Cells as a biomarker of inflammatory status and a promising target against cardiac rejection in heart transplanted patients

Portuguese Transplant Society

Funders: N/A

2019/01/01 - 2020/12/01

MicroRNAs as markers of disturbed adipose tissue function and inflammation - a potential mechanism for diabetes development in obesity

COM Child Health project grant


University of Arkansas for Medical Sciences

2019/01/01 - 2019/12/01

Role of Regulatory T-cells in Obesity-Linked Insulin Resistance and Diabetes

COM Sturgis project grant


University of Arkansas for Medical Sciences

Funders: N/A

2019/03/01 - 2020/12/01

CD20+ T Cells as a biomarker of inflammatory status and a promising target against cardiac rejection in heart transplanted patients

Portuguese Transplant Society


2018 - 2021

Antipsychotic drug induced metabolic dysfunction – in vivo studies with 2 specific drugs



2018/02/01 - 2020/01/01

Effects of PTP1b modulation on Wound Healing, in vitro and in vivo systems



Diabetes UK

Funders: Diabetes UK

2018/11/01 - 2021/12/01

Contribution of Psychological Factors in Diabetic Foot Ulcer Healing; in Physiological Indicators of Wound Healing Prognosis and Quality of Life: A Randomized Longitudinal Effectiveness Evaluation

02/SAICT/2017 – SAICT


Fundação para a Ciência e a Tecnologia

2017 - 2019/12

Microbiome of the diabetic foot ulcer in human subjects.



2017 - 2019/12/31

Assessment of oxidative capacity in obese children.



2017 - 2019/12

Establishing the presence of mitochondrial dysfunction and oxidative stress and the relationships with resting energy expenditure and fatty acid oxidation in childhood obesity.



2017 - 2019/12

European and Portuguese funds for Human Resources



2016 - 2018

Combination therapy synergistically accelerates diabetic wound closure.

European Research Program in Microvascular Complications of Diabetes supported by Novartis


European Foundation for the Study of Diabetes

2015/06 - 2016/06

Oxidative capacity of circulating cells and muscle fibers in the elderly



University of Arkansas for Medical Sciences

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