Henrique Bernardo da Silva

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Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.

Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices

Silva, Henrique, Scientific Reports. 1. 11. 2021. http://dx.doi.org/10.1038/s41598-021-89964-0 . 10.1038/s41598-021-89964-0 . Scientific Reports

Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3am-/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A2A Receptor Blockade

Ana Moreira-de-Sá; Francisco Q. Gonçalves; João P. Lopes; Henrique B. Silva; Ângelo R. Tomé; Rodrigo A. Cunha; Paula M. Canas, Molecular Neurobiology. 2543 - 2557. 6. 58. 2021. https://doi.org/10.1007/s12035-020-02275-9 . 10.1007/s12035-020-02275-9 . Molecular Neurobiology

Exercise decreases aberrant corticostriatal plasticity in an animal model of l-DOPA-induced dyskinesia.

Silva, Henrique, American journal of physiology. Regulatory, integrative and comparative physiology. 2021. https://doi.org/10.1152/ajpregu.00295.2020 . 10.1152/ajpregu.00295.2020 . American journal of physiology. Regulatory, integrative and comparative physiology

Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

Silva, Henrique, Neurobiology of Disease. 105137 - 105137. 146. 2020. http://dx.doi.org/10.1016/j.nbd.2020.105137 . 10.1016/j.nbd.2020.105137 . Neurobiology of Disease

Control of NMDA Receptor-Mediated Currents by Adenosine A1 and A2A Receptors Within the Basolateral Amygdala

Silva, Henrique; Anna Pliássova; Margarida Henriques; Henrique B. Silva; Paula Agostinho; Rodrigo A. Cunha; Samira G. Ferreira, Journal of Caffeine and Adenosine Research. 61 - 70. 2. 10. 2020. http://dx.doi.org/10.1089/caff.2019.0024 . 10.1089/caff.2019.0024 . Journal of Caffeine and Adenosine Research

Synaptic and memory dysfunction in a ß-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine

Silva, Henrique; Goncalves, Francisco Q.; Lopes, Joao P.; Silva, Henrique B.; Lemos, Cristina; Silva, Antonio C.; Goncalves, Nell; et al, Neurobiology of Disease. 2019. http://dx.doi.org/10.1016/j.nbd.2019.104570 . 10.1016/j.nbd.2019.104570 . Neurobiology of Disease

Adenosine A 1 and A 2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus

Silva, Henrique, Journal of Neurochemistry. 2019. http://dx.doi.org/10.1111/jnc.14816 . 10.1111/jnc.14816 . Journal of Neurochemistry

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus

Duarte, Joao M. N.; Skoug, Cecilia; Silva, Henrique B.; Carvalho, Rui A.; Gruetter, Rolf; Cunha, Rodrigo A., Frontiers in Neuroscience. 2019. https://publons.com/publon/6660710/ . 10.3389/FNINS.2018.01015 . Frontiers in Neuroscience

Expression of potassium channels is relevant for cell survival and migration in a murine bone marrow stromal cell line

Silva, Henrique B.; Rodrigues, Deivid C.; Andrade, Raiana; Teixeira, Gabriel H. G. S. F.; Stelling, Mariana P.; Ponte, Cristiano G.; Nascimento, Jose H. M.; et al, Journal of Cellular Physiology. 2019. https://publons.com/publon/19495346/ . 10.1002/JCP.28441 . Journal of Cellular Physiology

Adenosine A1 and A2A receptors differently control synaptic plasticity in the mouse dorsal and ventral hippocampus

Reis, Sara L.; Silva, Henrique B.; Almeida, Margarida; Cunha, Rodrigo A.; Simoes, Ana P.; Canas, Paula M., Journal of Neurochemistry. 2019. https://publons.com/publon/28688848/ . 10.1111/JNC.14816 . Journal of Neurochemistry

Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making

Leffa, Douglas T.; Pandolfo, Pablo; Goncalves, Nelio; Machado, Nuno J.; de Souza, Carolina M.; Real, Joana I.; Silva, Antonio C.; et al, Frontiers in Molecular Neuroscience. 2018. https://publons.com/publon/15617083/ . 10.3389/FNMOL.2018.00475 . Frontiers in Molecular Neuroscience

Neuronal adenosine A2A receptors are critical mediators of neurodegeneration triggered by convulsions

Canas, P.M.; Porciúncula, L.O.; Simões, A.P.; Augusto, E.; Silva, H.B.; Machado, N.J.; Gonçalves, N.; et al, eNeuro. 6. 5. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85059796352&partnerID=MN8TOARS . 10.1523/ENEURO.0385-18.2018 . eNeuro

Blockade of adenosine A2AR receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease

Silva, A.C.; Lemos, C.; Gonçalves, F.Q.; Pliássova, A.V.; Machado, N.J.; Silva, H.B.; Canas, P.M.; et al, Neurobiology of Disease. 72 - 81. 117. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048494541&partnerID=MN8TOARS . 10.1016/j.nbd.2018.05.024 . Neurobiology of Disease

Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision Making

Silva, H., Frontiers in Molecular Neuroscience. 11. 2018. http://dx.doi.org/10.3389/fnmol.2018.00475 . 10.3389/fnmol.2018.00475 . Frontiers in Molecular Neuroscience

Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A(2A) Receptor in Hippocampal Glutamate Synapses

Machado, Nuno J.; Simoes, Ana Patricia; Silva, Henrique B.; Ardais, Ana Paula; Kaster, Manuella P.; Garcao, Pedro; Rodrigues, Diana I.; et al, Molecular Neurobiology. 1552 - 1563. 2. 54. 2017. https://publons.com/publon/6042063/ . 10.1007/S12035-016-9774-9 . Molecular Neurobiology

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid ß (Aß1-40) administration in mice

Santos, V.V.; Stark, R.; Rial, D.; Silva, H.B.; Bayliss, J.A.; Lemus, M.B.; Davies, J.S.; et al, Journal of Neuroendocrinology. 5. 29. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019741164&partnerID=MN8TOARS . 10.1111/jne.12476 . Journal of Neuroendocrinology

HIGH SUCROSE CONSUMPTION INDUCES MEMORY IMPAIRMENT IN RATS ASSOCIATED WITH ELECTROPHYSIOLOGICAL MODIFICATIONS BUT NOT WITH METABOLIC CHANGES IN THE HIPPOCAMPUS

Lemos, C.; Rial, D.; Goncalves, F. Q.; Pires, J.; Silva, H. B.; Matheus, F. C.; Da Silva, A. C.; et al, Neuroscience. 2016. https://publons.com/publon/792536/ . 10.1016/J.NEUROSCIENCE.2015.12.018 . Neuroscience

"The adenosine facilitation of synaptic plasticity in cortico-striatal synapses is co-operated by the pre-synaptic and astrocytic A2A receptors" Abstracts of the Brazilian Purine Club Meeting

Silva, H., Purinergic Signalling. 343 - 410. 2. 12. 2016. http://dx.doi.org/10.1007/s11302-016-9503-x . 10.1007/s11302-016-9503-x . Purinergic Signalling

High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus.

Lemos C; Rial D; Gonçalves FQ; Pires J; Silva HB; Matheus FC; da Silva AC; et al, 2015. http://europepmc.org/abstract/med/26704636 . 10.1016/j.neuroscience.2015.12.018 .

The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system.

Lopes JP; Morató X; Souza C; Pinhal C; Machado NJ; Canas PM; Silva HB; et al, Journal of Neurochemistry. 2015. http://europepmc.org/abstract/med/25824528 . 10.1111/jnc.13109 . Journal of Neurochemistry

Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models

Li, Wei; Silva, Henrique B.; Real, Joana; Wang, Yu-Mei; Rial, Daniel; Li, Ping; Payen, Marie-Pierce; et al, Neurobiology of Disease. 2015. https://publons.com/publon/2840189/ . 10.1016/J.NBD.2015.03.030 . Neurobiology of Disease

Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress

Kaster, Manuella P.; Machado, Nuno J.; Silva, Henrique B.; Nunes, Ana; Ardais, Ana Paula; Santana, Magda; Baqi, Younis; et al, Proceedings of the National Academy of Sciences. 2015. https://publons.com/publon/3278967/ . 10.1073/PNAS.1423088112 . Proceedings of the National Academy of Sciences

The effects of different concentrations of the alpha(2)-adrenoceptor agonist medetomidine on basal excitatory synaptic transmission and synaptic plasticity in hippocampal slices of adult mice

Ribeiro, P.O.; Antunes, L.M.; Nunes, C.S.; Silva, H.B.; Cunha, R.A.; Tomé, Â.R., Anesthesia and Analgesia. 1130 - 1137. 5. 120. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937967119&partnerID=MN8TOARS . 10.1213/ANE.0000000000000636 . Anesthesia and Analgesia

Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices

Ribeiro, P.O.; Tomé, Â.R.; Silva, H.B.; Cunha, R.A.; Antunes, L.M.; Ribeiro, Patricia O.; Tome, Angelo R.; et al, Brain Research. 10 - 17. 1560. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898450346&partnerID=MN8TOARS . 10.1016/j.brainres.2014.03.004 . Brain Research

"Synaptic and glia involvement in the purinergic control of neurodegenerative diseases" Abstracts from Purines 2014, an International Conference on Nucleotides, Nucleosides and Nucleobases, held in Bonn, Germany, from July 23¿-27, 2014.

Silva, H., Purinergic Signalling. 657 - 854. 4. 10. 2014. http://dx.doi.org/10.1007/s11302-014-9430-7 . 10.1007/s11302-014-9430-7 . Purinergic Signalling

Hippocampal long-term potentiation in adult mice after recovery from ketamine anesthesia

Ribeiro, Patricia O.; Silva, Henrique B.; Tome, Angelo R.; Cunha, Rodrigo A.; Antunes, Luis M.; Ribeiro PO; Silva HB; et al, Lab Animal. 2014. https://publons.com/publon/33740/ . 10.1038/LABAN.571 . Lab Animal

Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

Rial, Daniel; Castro, Adalberto A.; Machado, Nuno; Garcao, Pedro; Goncalves, Francisco Q.; Silva, Henrique B.; Tome, Angelo R.; et al, Plos One. 2014. https://publons.com/publon/9695654/ . 10.1371/JOURNAL.PONE.0114216 . Plos One

Inhibition of ecto-5 '-nucleotidase activity facilitates short-term and inhibits long-term plasticity in two different mouse brain regions

Goncalves, Francisco Queiroz; Rial, Daniel; Silva, Henrique; Cunha, Rodrigo, Purinergic Signalling. 2014. https://publons.com/publon/29972398/ . Purinergic Signalling

Synaptic and glia involvement in the purinergic control of neurodegenerative diseases

Canas, Paula M.; Rial, Daniel; Simoes, Ana Patricia; Lopes, Joao Pedro; Silva, Henrique B.; Machado, Nuno J.; Queiroz, Francisco; et al, Purinergic Signalling. 2014. https://publons.com/publon/8181585/ . Purinergic Signalling

Effects of medetomidine on basal excitatory synaptic transmission and on synaptic plasticity in mice hippocampal slices

P. Ribeiro; H. B. Silva; R. A. Cunha; L. M. Antunes; Â. R. Tomé, European Journal of Anaesthesiology. 2013. https://publons.com/publon/47015378/ . 10.1097/00003643-201306001-00338 . European Journal of Anaesthesiology

Ketamine affects basal synaptic transmission and long-term potentiation without affect pair-pulse facilitation in hippocampal slices of adult mice

P. Ribeiro; A. Tomé; H. Silva; R. Cunha; L. M. Antunes, European Journal of Anaesthesiology. 2012. https://publons.com/publon/47015288/ . 10.1097/00003643-201206001-00353 . European Journal of Anaesthesiology

"Absence of synaptic modifications related to adenosine A1 receptor-mediated control of restraint-stress-induced preconditioning" Purines 2010: Adenine Nucleosides and Nucleotides in Biomedicine

Silva, H., Purinergic Signalling. 1 - 162. S1. 6. 2010. http://dx.doi.org/10.1007/s11302-010-9187-6 . 10.1007/s11302-010-9187-6 . published Purinergic Signalling

Absence of synaptic modifications related to adenosine A1 receptor-mediated control of restraint-stress-induced preconditioning

Silva, Henrique; Tome, Angelo; Kaster, Manuella; Souza, Carolina; Andrade, Geanne; Canas, Paula; Agostinho, Paula; Cunha, Rodrigo, Purinergic Signalling. 2010. https://publons.com/publon/12982137/ . Purinergic Signalling

Role of The Purinergic Neuromodulation System in Epilepsy

Ângelo R. Tomé; Henrique Silva; Rodrigo A. Cunha, TONEURJ. 64 - 83. 1. 4. 2010. http://dx.doi.org/10.2174/1874082001004010064 . 10.2174/1874082001004010064 . TONEURJ

Voltage-dependent calcium and chloride currents in s17 bone marrow stromal cell line

Silva, H.B.; Medei, E.; Rodrigues, D.C.; Rondinelli, E.; Almeida, N.A.S.; Goldenberg, R.C.S.; Campos De Carvalho, A.C.; et al, Journal of Cellular Physiology. 244 - 251. 1. 223. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-75749095604&partnerID=MN8TOARS . 10.1002/jcp.22030 . Journal of Cellular Physiology

"Contribution of Endothelium and Smooth Muscle Cells to Vascular Contraction in a Cholesterol-enriched Environment" Proceedings of the British Pharmacological Society meeting. 14-16 December 1994. Abstracts. 185P

Silva, H., British journal of pharmacology. 1995. https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7773554/?tool=EBI . British journal of pharmacology

"Cholesterol-enriched Diets Modify Vascular Responses in NZW Rabbits" In Proceedings of the 8th Meeting on Adrenergic Mechanisms, Porto, Portugal, 20¿-22 September 1993

Silva, H., Journal of Autonomic Pharmacology. 1 - 1. 1. 14. 1994. http://dx.doi.org/10.1111/j.1474-8673.1994.tb00579.x . 10.1111/j.1474-8673.1994.tb00579.x . published Journal of Autonomic Pharmacology

"Effect of a Cholestrol Enriched-diet on Ghosts and Vascular Wall Membranes in NZW Rabitts" In: XIIth International Congress Of Pharmacology, Montreal - ABSTRACTS/RÉSUMÉS : 26th Winter Meeting

Silva, H., Canadian Journal of Physiology and Pharmacology. Ai - Axxxi. 2. 72. 1994. http://dx.doi.org/10.1139/y94-029 . 10.1139/y94-029 . published Canadian Journal of Physiology and Pharmacology

Determinação da Fluidez Membranar em Três Tipos de Membranas Celulares de Coelho Albinos Neozelandeses (NZW) - Aferição do Método.

Silva, H., Boletim da Faculdade de Farmácia, Coimbra. 87 - 95. 2. 15. 1992. published Boletim da Faculdade de Farmácia, Coimbra

All projects

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Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.

2018/07/01 - 2021/06/30

Recetores A2A da adenosina como desencadeadores de disfunção mnemónica na doença de Alzheimer: mecanismos e possibilidade terapêutica

PTDC/MED-NEU/31274/2017

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2016/05/01 - 2019/07/31

Papel dos astrócitos no controlo da memória- foco nos recetores adenosina A2A

PTDC/NEU-NMC/4154/2014

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012/05 - 2014/08

Physiopathological role of ecto-5`-nucleotidase - a new target for neuroprotection

Provided by PTCRIS: 122005

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2012/05/01 - 2014/08/31

Papel fisio-patológico da ecto-5`-nucleotidase - um novo alvo para neuroprotecção

PTDC/SAU-TOX/122005/2010

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012/04/01 - 2014/09/30

Papel do accumbens e amigdala no controlo da neuropatologia causada por stress crónico

PTDC/SAU-NSC/122254/2010

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012/04 - 2014/09

Role of accumbens and amygdala in the control of chronic stress neuropathology

Provided by PTCRIS: 122254

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2011/08 - 2013/12

Localization and metabolism of APP controlling synaptic degeneration in animal models of Alzheimer's disease

Provided by PTCRIS: 114810

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2011 - 2013

CAPES/FCT - Cooperação Internacional Brasil - Portugal: Mecanismos moleculares subjacentes à prevenção pela cafeína no comprometimento da memória em modelos animais,

fixed-23478

Researcher

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação para a Ciência e a Tecnologia

2011/08/23 - 2013/12/31

Localização e metabolismo da APP e relação com o controlo da degeneração sináptica em modelos animais da doença de Alzheimer

PTDC/SAU-NMC/114810/2009

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03/18 - 2012/09/17

Papel do ATP e dos seus receptores P2Y1 na neuroprotecção

PTDC/SAU-FCF/100423/2008

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03 - 2012/06

Demonstrating that A2A adenosine receptors control glutamatergic synaptic plasticity through CB1 cannabinoid receptors in the striatum, thus providing attracting therapeutic targets

Provided by PTCRIS: 100729

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/03 - 2012/09

Role of ATP and its P2Y1 receptors in neuroprotection

Provided by PTCRIS: 100423

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/03 - 2012/02

Role of adenosine A2A receptors in microglia and glutamatergic synapses in the control of synaptic plasticity and brain damage

Provided by PTCRIS: 108668

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/03/18 - 2012/02/29

Papel dos receptores A2A da adenosina localizados na microglia e em terminais glutamatérgicos no controlo da plasticidade sináptica e dano cerebral

PTDC/SAU-NEU/108668/2008

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03/17 - 2012/06/16

Demonstração de que os receptores de adenosina A2A controlam a plasticidade sináptica glutamatergica via dos receptores de canabinóide CB1 no corpo estriado, fornecendo assim alvos terapêuticos atrativos

PTDC/SAU-NEU/100729/2008

Universidade de Coimbra Centro de Neurociências e Biologia Celular; University of Aberdeen Institute of Medical Sciences

Funders: Fundação para a Ciência e a Tecnologia

2009/07/01 - 2014/05/03

CIÊNCIA 2008 – HENRIQUE SILVA

CONT_DOUT/6/CNC/3281/10348/ 11/2008

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2007/09/01 - 2008/09/30

"Purinergic receptors characterization of Human Sertoli cells" - Undergraduate Science Research.

IPG-152

Principal investigator

Rectory of Oporto University /Caixa Geral de Depósitos.

Funders: Rectory of Oporto University /Caixa Geral de Depósitos.

2006 - 2008/09

“Electrophysiological characterization of ionic channels of human seminiferous epithelial cells”

POCTI/BCI/48376/2002

Post-doc Fellow

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar; Universidade do Porto Centro de Estudos de Ciencia Animal

Funders: Associação para a Inovação e Desenvolvimento da FCT

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