Lino Ferreira

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Antimicrobial Peptide-Tether Dressing Able to Enhance Wound Healing by Tissue Contact

Akhilesh Rai; Rafaela Ferrão; Denise Marta; Andreia Vilaça; Miguel Lino; Tiago Rondão; Jian Ji; Artur Paiva; Lino Ferreira, ACS Applied Materials & Interfaces. 2022. . 10.1021/acsami.2c06601 . ACS Applied Materials & Interfaces

Antimicrobial peptide-based materials: opportunities and challenges

Akhilesh Rai; Rafaela Ferrão; Paulo Palma; Tatiana Patricio; Paula Parreira; Elsa Anes; Chiara Tonda-Turo; et al, Journal of Materials Chemistry B. 2022. . 10.1039/D1TB02617H . Journal of Materials Chemistry B

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira, Food and Chemical Toxicology. 111967 - 111967. 149. 2021. . 10.1016/j.fct.2021.111967 . Food and Chemical Toxicology

Revisiting gene delivery to the brain: silencing and editing

João Conniot; Sepehr Talebian; Susana Simões; Lino Ferreira; João Conde, Biomaterials Science. 1065 - 1087. 4. 9. 2021. . 10.1039/D0BM01278E . Biomaterials Science

Biomedical applications of the peptide decorated gold nanoparticles

Rai, Akhilesh; Ferreira, Lino, Critical Reviews in Biotechnology. 186 - 215. 2. 41. 2021. . 10.1080/07388551.2020.1853031 . Critical Reviews in Biotechnology

Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions

Estronca, Luís; Francisco, Vitor; Pitrez, Patrícia; Honório, Inês; Carvalho, Lara; Vazão, Helena; Blersch, Josephine; et al, Nanoscale Horizons. 2021. . 10.1039/d0nh00550a . published Nanoscale Horizons

Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation

Almeida, Henrique V.; Tenreiro, Miguel F.; Louro, Ana F.; Abecasis, Bernardo; Santinha, Deolinda; Calmeiro, Tomás; Fortunato, Elvira; et al, ACS Applied Bio Materials. 1888 - 1899. 2. 4. 2021. . 10.1021/acsabm.0c01490 . ACS Applied Bio Materials

High-throughput screening of nanoparticles in drug delivery

Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira, APL Bioengineering. 2021. . 10.1063/5.0057204 . APL Bioengineering

Re-Use of Caco-2 Monolayers in Permeability Assays—Validation Regarding Cell Monolayer Integrity

Pires, Cristiana L.; Praça, Catarina; Martins, Patrícia A. T.; Batista de Carvalho, Ana L. M.; Ferreira, Lino; Marques, Maria Paula M.; Moreno, Maria João, Pharmaceutics. 10. 13. 2021. . 10.3390/pharmaceutics13101563 . Pharmaceutics

Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization

Tenreiro, Miguel F.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino; Alves, Paula M.; Serra, Margarida, Scientific Reports. 1. 11. 2021. . 10.1038/s41598-021-00226-5 . Scientific Reports

Engineered extracellular vesicles as brain therapeutics

Lino, Miguel M.; Simões, Susana; Tomatis, Francesca; Albino, Inês; Barrera, Angela; Vivien, Denis; Sobrino, Tomas; Ferreira, Lino, Journal of Controlled Release. 472 - 485. 338. 2021. . 10.1016/j.jconrel.2021.08.037 . Journal of Controlled Release

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke

Bernardo-Castro, Sara; Albino, Inês; Barrera-Sandoval, Ángela María; Tomatis, Francesca; Sousa, João André; Martins, Emanuel; Simões, Susana; et al, Life. 6. 11. 2021. . 10.3390/life11060482 . Life

Exogenous loading of miRNAs into small extracellular vesicles

Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al, Journal of Extracellular Vesicles. 10. 10. 2021. . 10.1002/jev2.12111 . Journal of Extracellular Vesicles

Antimicrobial and pro-angiogenic properties of soluble and nanoparticle-immobilized LL37 peptides

Michela Comune; Akhilesh Rai; Paulo Palma; Chiara TondaTuro; Lino Ferreira, Biomaterials Science. 2021. . 10.1039/D1BM01034D . Biomaterials Science

Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.

Buczak K; Kirkpatrick JM; Truckenmueller F; Santinha D; Ferreira L; Roessler S; Singer S; Beck M; Ori A, Nature protocols. 2020. . 10.1038/s41596-020-0356-y . Nature protocols

A Light-Triggerable Nanoparticle Library for the Controlled Release of Non-Coding RNAs

Blersch, Josephine; Francisco, Vitor; Rebelo, Catarina; Jiménez-Balsa, Adrian; Antunes, Helena; Gonzato, Carlo; Pinto, Sandra; et al, Angewandte Chemie International Edition. 1985 - 1991. 5. 59. 2020. . 10.1002/anie.201911398 . Angewandte Chemie International Edition

A light-triggerable formulation to control the stability of pro-angiogenic transcription factor hypoxia inducible factor-1a (HIF-1a)

Josephine Blersch; Vitor Francisco; Catarina Rebelo; Adrian Jiménez-Balsa; Helena Antunes; Sandra Pinto; Susana Simões; Akhilesh Rai; Lino Ferreira, Nanoscale. 2020. . 10.1039/C9NR10503D . Nanoscale

Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.

Pitrez PR; Estronca L; Monteiro LM; Colell G; Vazão H; Santinha D; Harhouri K; et al, Nature communications. 2020. . 10.1038/s41467-020-17901-2 . Nature communications

Native and bioengineered extracellular vesicles for cardiovascular therapeutics.

de Abreu RC; Fernandes H; da Costa Martins PA; Sahoo S; Emanueli C; Ferreira L, Nature reviews. Cardiology. 2020. . 10.1038/s41569-020-0389-5 . Nature reviews. Cardiology

Permeability of the blood brain barrier through the phases of ischemic stroke and relation with clinical outcome: protocol for a systematic review

Ferreira, Lino, BMJ Open. 9. 10. 2020. published BMJ Open

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Bernardo-Castro, Sara; Sousa, João André; Brás, Ana; Cecília, Carla; Rodrigues, Bruno; Almendra, Luciano; Machado, Cristina; et al, Frontiers in Neurology. 11. 2020. . 10.3389/fneur.2020.594672 . Frontiers in Neurology

A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies

Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino, Methods. 2020. . 10.1016/j.ymeth.2020.12.002 . Methods

Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine

Raquel Ferreira; Joseph Napoli; Tariq Enver; Liliana Bernardino; Lino Ferreira, Nature Communications. 2020. . 10.1038/s41467-020-18042-2 . Nature Communications

A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity

Ferreira, Lino, Current Protocols in Stem Cell Biology. 2019. . 10.1002/cpsc.93 . Current Protocols in Stem Cell Biology

A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles

Arnab Banerjee; Vitor Alves; Tiago Rondão; José Sereno; Ângela Neves; Miguel Lino; Andreia Ribeiro; Antero J. Abrunhosa; Lino S. Ferreira, Nanoscale. 13243 - 13248. 28. 11. 2019. . 10.1039/C9NR02512J . Nanoscale

A photodynamic antibacterial spray-coating based on the host–guest immobilization of the photosensitizer methylene blue

Tian-tian Yao; Jing Wang; Yun-fan Xue; Wei-jiang Yu; Qiang Gao; Lino Ferreira; Ke-Feng Ren; Jian Ji, Journal of Materials Chemistry B. 2019. . 10.1039/C9TB01069F . Journal of Materials Chemistry B

A near infrared light-triggerable modular formulation for the delivery of small biomolecules

Ferreira, Lino, Journal of Nanobiotechnology. 2019. . 10.1186/s12951-019-0530-y . Journal of Nanobiotechnology

A light-triggerable nanoparticle library for the controlled release of non-coding RNAs.

Ferreira, Lino, Angewandte Chemie (International ed. in English). 2019. . 10.1002/anie.201911398 . Angewandte Chemie (International ed. in English)

Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells.

Ferreira, Lino, Stem cell reports. 2019. . 10.1016/j.stemcr.2019.08.002 . Stem cell reports

Spatially Confining Surface Roughness on Exponentially Growing Polyelectrolyte Multilayer Films

Ferreira, Lino, Advanced Materials Interfaces. 2019. . 10.1002/admi.201900702 . Advanced Materials Interfaces

The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration

Ferreira, Lino, ACS Nano. 2019. . 10.1021/acsnano.9b00376 . ACS Nano

What human blood-brain barrier models can tell us about BBB function and drug discovery?

Ferreira, Lino, Expert opinion on drug discovery. 2019. . 10.1080/17460441.2019.1646722 . Expert opinion on drug discovery

Functional characterization of iPSC-derived arterial- and venous-like endothelial cells

Ferreira, Lino, Scientific Reports. 2019. . 10.1038/s41598-019-40417-9 . Scientific Reports

Bioprocess decision support tool for scalable manufacture of extracellular vesicles

Ferreira, Lino, Biotechnology and Bioengineering. 2019. . 10.1002/bit.26809 . Biotechnology and Bioengineering

Unveiling the molecular crosstalk in a human induced pluripotent stem cell-derived cardiac model

Bernardo Abecasis; Patrícia Gomes-Alves; Susana Rosa; Pedro J. Gouveia; Lino Ferreira; Margarida Serra; Paula M. Alves, Biotechnology and Bioengineering. 1245 - 1252. 5. 116. 2019. . 10.1002/bit.26929 . Biotechnology and Bioengineering

Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation

Ferreira, Lino, Scientific Reports. 2018. . 10.1038/s41598-018-25517-2 . Scientific Reports

Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

Ferreira, Lino, Cell Reports. 2018. . 10.1016/j.celrep.2018.11.032 . Cell Reports

A nanoformulation for the preferential accumulation in adult neurogenic niches

Ferreira, Lino, Journal of Controlled Release. 2018. . 10.1016/j.jconrel.2018.06.013 . Journal of Controlled Release

Cecropin-Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation

Ferreira, Lino, Advanced Materials Interfaces. 2018. . 10.1002/admi.201801390 . Advanced Materials Interfaces

STROKE34 Study Protocol: A Randomized Controlled Phase IIa Trial of Intra-Arterial CD34+ Cells in Acute Ischemic Stroke

Ferreira, Lino, Frontiers in Neurology. 2018. . 10.3389/fneur.2018.00302 . Frontiers in Neurology

Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain

Ferreira, Lino, Neuroscience Letters. 2018. . 10.1016/j.neulet.2018.02.066 . Neuroscience Letters

MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo

Ferreira, Lino, PLOS ONE. 2018. . 10.1371/journal.pone.0193609 . PLOS ONE

Endothelial Progenitor Cells influence acute and subacute stroke hemodynamics

Ferreira, Lino, Journal of the Neurological Sciences. 2018. . 10.1016/j.jns.2017.12.028 . Journal of the Neurological Sciences

Light-triggerable formulations for the intracellular controlled release of biomolecules.

Lino MM; Ferreira L, Drug discovery today. 2018. . 10.1016/j.drudis.2018.01.019 . Drug discovery today

Stem cells as vehicles and targets of nanoparticles.

Pinho S; Macedo MH; Rebelo C; Sarmento B; Ferreira L, Drug discovery today. 2018. . 10.1016/j.drudis.2018.01.030 . Drug discovery today

Atomistic-Level Investigation of a LL37-Conjugated Gold Nanoparticle By Well-Tempered Metadynamics

André F. Ferreira; Michela Comune; Akhilesh Rai; Lino Ferreira; Pedro N. Simões, The Journal of Physical Chemistry B. 2018. . 10.1021/acs.jpcb.8b05717 . The Journal of Physical Chemistry B

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

Miguel M. Lino; Susana Simões; Andreia Vilaça; Helena Antunes; Alessandra Zonari; Lino Ferreira, ACS Nano. 2018. . 10.1021/acsnano.7b07538 . ACS Nano

Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules

Adrián Jiménez-Balsa; Sandra Pinto; Emanuel Quartin; Miguel M. Lino; Vitor Francisco; Lino Ferreira, Bioconjugate Chemistry. 2018. . 10.1021/acs.bioconjchem.7b00820 . Bioconjugate Chemistry

Substrate Topography Modulates Cell Aging on a Progeria Cell Model

Patricia R. Pitrez; Luís Estronca; Helena Vazão; Anne-Laure Egesipe; Amélie Le Corf; Claire Navarro; Nicolas Lévy; et al, ACS Biomaterials Science & Engineering. 2018. . 10.1021/acsbiomaterials.8b00224 . ACS Biomaterials Science & Engineering

Endothelial progenitor cells enhance blood-brain barrier permeability in subacute stroke.

Sargento-Freitas J; Aday S; Nunes C; Cordeiro M; Gouveia A; Silva F; Machado C; et al, Neurology. 2018. . 10.1212/wnl.0000000000004801 . Neurology

High-throughput identification of small molecules that affect human embryonic vascular development.

Vazão H; Rosa S; Barata T; Costa R; Pitrez PR; Honório I; de Vries MR; et al, Proceedings of the National Academy of Sciences of the United States of America. 2017. . 10.1073/pnas.1617451114 . Proceedings of the National Academy of Sciences of the United States of America

Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model.

Ribas J; Zhang YS; Pitrez PR; Leijten J; Miscuglio M; Rouwkema J; Dokmeci MR; et al, Small (Weinheim an der Bergstrasse, Germany). 2017. . 10.1002/smll.201603737 . Small (Weinheim an der Bergstrasse, Germany)

Challenging the great vascular wall: Can we envision a simple yet comprehensive therapy for stroke?

Machado-Pereira M; Santos T; Ferreira L; Bernardino L; Ferreira R, Journal of tissue engineering and regenerative medicine. 2017. . 10.1002/term.2427 . Journal of tissue engineering and regenerative medicine

Restoring heart function and electrical integrity: closing the circuit.

Monteiro LM; Vasques-Nóvoa F; Ferreira L; Pinto-do-Ó P; Nascimento DS, NPJ Regenerative medicine. 2017. . 10.1038/s41536-017-0015-2 . NPJ Regenerative medicine

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition.

Aday S; Zoldan J; Besnier M; Carreto L; Saif J; Fernandes R; Santos T; et al, Nature communications. 2017. . 10.1038/s41467-017-00746-7 . Nature communications

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes.

Gouveia PJ; Rosa S; Ricotti L; Abecasis B; Almeida HV; Monteiro L; Nunes J; et al, Biomaterials. 2017. . 10.1016/j.biomaterials.2017.05.048 . Biomaterials

Erratum: Restoring heart function and electrical integrity: Closing the circuit.

Monteiro LM; Vasques-Nóvoa F; Ferreira L; Pinto-do-Ó P; Nascimento DS, NPJ Regenerative medicine. 2017. . 10.1038/s41536-017-0020-5 . NPJ Regenerative medicine

Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential.

Comune M; Rai A; Chereddy KK; Pinto S; Aday S; Ferreira AF; Zonari A; et al, Journal of controlled release : official journal of the Controlled Release Society. 2017. . 10.1016/j.jconrel.2017.07.007 . Journal of controlled release : official journal of the Controlled Release Society

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis.

Ribeiro-Rodrigues TM; Laundos TL; Pereira-Carvalho R; Batista-Almeida D; Pereira R; Coelho-Santos V; Silva AP; et al, Cardiovascular research. 2017. . 10.1093/cvr/cvx118 . Cardiovascular research

Intracellular delivery of more than one protein with spatio-temporal control

Miguel M. Lino; Susana Simões; Sónia Pinho; Lino Ferreira; Lino MM; Simões S; Pinho S; Ferreira L, Nanoscale. 18668 - 18680. 47. 9. 2017. . 10.1039/C7NR02414B . Nanoscale

Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles

Ferreira, Lino, Mediators of Inflammation. 2017. . 10.1155/2017/6742427 . Mediators of Inflammation

Findings on the interaction of the antimicrobial peptide cecropin-melittin with a gold surface from molecular dynamics studies

Ferreira, Lino, European Biophysics Journal. 2017. . 10.1007/s00249-016-1160-z . European Biophysics Journal

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles.

Santos T; Ferreira R; Quartin E; Boto C; Saraiva C; Bragança J; Peça J; et al, Acta biomaterialia. 2017. . 10.1016/j.actbio.2017.06.044 . Acta biomaterialia

Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.

Blondel S; Egesipe AL; Picardi P; Jaskowiak AL; Notarnicola M; Ragot J; Tournois J; et al, Cell death & disease. 2016. . 10.1038/cddis.2015.374 . Cell death & disease

High-density antimicrobial peptide coating with broad activity and low cytotoxicity against human cells.

Rai A; Pinto S; Evangelista MB; Gil H; Kallip S; Ferreira MG; Ferreira L, Acta biomaterialia. 2016. . 10.1016/j.actbio.2016.01.035 . Acta biomaterialia

Retinoic acid-loaded polymeric nanoparticles enhance vascular regulation of neural stem cell survival and differentiation after ischaemia.

Ferreira R; Fonseca MC; Santos T; Sargento-Freitas J; Tjeng R; Paiva F; Castelo-Branco M; Ferreira LS; Bernardino L, Nanoscale. 2016. . 10.1039/c5nr09077f . Nanoscale

One-step synthesis of high-density peptide-conjugated gold nanoparticles with antimicrobial efficacy in a systemic infection model.

Rai A; Pinto S; Velho TR; Ferreira AF; Moita C; Trivedi U; Evangelista M; et al, Biomaterials. 2016. . 10.1016/j.biomaterials.2016.01.051 . Biomaterials

High Antimicrobial Activity and Low Human Cell Cytotoxicity of Core-Shell Magnetic Nanoparticles Functionalized with an Antimicrobial Peptide.

Maleki H; Rai A; Pinto S; Evangelista M; Cardoso RM; Paulo C; Carvalheiro T; et al, ACS applied materials & interfaces. 2016. . 10.1021/acsami.6b03355 . ACS applied materials & interfaces

Traceable microRNA-124 loaded nanoparticles as a new promising therapeutic tool for Parkinson's disease.

Saraiva C; Ferreira L; Bernardino L, Neurogenesis (Austin, Tex.). 2016. . 10.1080/23262133.2016.1256855 . Neurogenesis (Austin, Tex.)

Nanomedicine Approaches to Modulate Neural Stem Cells in Brain Repair.

Santos T; Boto C; Saraiva CM; Bernardino L; Ferreira L, Trends in biotechnology. 2016. . 10.1016/j.tibtech.2016.02.003 . Trends in biotechnology

Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases.

Saraiva C; Praça C; Ferreira R; Santos T; Ferreira L; Bernardino L, Journal of controlled release : official journal of the Controlled Release Society. 2016. . 10.1016/j.jconrel.2016.05.044 . Journal of controlled release : official journal of the Controlled Release Society

Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development

Ferreira, Lino, Applied In Vitro Toxicology. 2016. . 10.1089/aivt.2016.0002 . Applied In Vitro Toxicology

MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease.

Saraiva C; Paiva J; Santos T; Ferreira L; Bernardino L, Journal of controlled release : official journal of the Controlled Release Society. 2016. . 10.1016/j.jconrel.2016.06.005 . Journal of controlled release : official journal of the Controlled Release Society

Stem Cell-Based Human Blood-Brain Barrier Models for Drug Discovery and Delivery.

Aday S; Cecchelli R; Hallier-Vanuxeem D; Dehouck MP; Ferreira L, Trends in biotechnology. 2016. . 10.1016/j.tibtech.2016.01.001 . Trends in biotechnology

Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.

Kostic I; Fidalgo-Carvalho I; Aday S; Vazão H; Carvalheiro T; Grãos M; Duarte A; et al, Scientific reports. 2015. . 10.1038/srep16406 . Scientific reports

Vascular disease modeling using induced pluripotent stem cells: focus in Hutching-Gilford progeria syndrome.

Pitrez P; Rosa SC; Almeida C; Ferreira L, 2015. .

An overview of new translational, clinical and therapeutic perspectives in laminopathies and other nuclear envelope-related diseases.  Proceedings of the 1st French-Italian meeting on laminopathies & other nuclear envelope-related diseases

Ferreira, Lino, Orphanet Journal of Rare Diseases . 2015. 10.1186/1750-1172-10-S2-I1 . Orphanet Journal of Rare Diseases

Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease.

Esteves M; Cristóvão AC; Saraiva T; Rocha SM; Baltazar G; Ferreira L; Bernardino L, 2015. . 10.3389/fnagi.2015.00020 .

Development of a SMCs model from HGPS-iPS and proofs of principle.

Ferreira L, Orphanet journal of rare diseases. 2015. . 10.1186/1750-1172-10-s2-o3 . Orphanet journal of rare diseases

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells

Cecchelli, R.; Aday, S.; Sevin, E.; Almeida, C.; Culot, M.; Dehouck, L.; Coisne, C.; et al, PLoS ONE. 6. 9. 2014. . 10.1371/journal.pone.0099733 . PLoS ONE

Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles

Ferreira, Lino, RSC Adv.. 2014. . 10.1039/c4ra04041d . RSC Adv.

Boron nitride nanotube-mediated stimulation modulates F/G-actin ratio and mechanical properties of human dermal fibroblasts

Ricotti, L.; Das Neves, R.P.; Ciofani, G.; Canale, C.; Nitti, S.; Mattoli, V.; Mazzolai, B.; Ferreira, L.; Menciassi, A., Journal of Nanoparticle Research. 2. 16. 2014. . 10.1007/s11051-014-2247-z . Journal of Nanoparticle Research

Interaction of fullerene nanoparticles with biomembranes: From the partition in lipid membranes to effects on mitochondrial bioenergetics

Santos, S.M.; Dinis, A.M.; Peixoto, F.; Ferreira, L.; Jurado, A.S.; Videira, R.A., Toxicological Sciences. 117 - 129. 1. 138. 2014. . 10.1093/toxsci/kft327 . Toxicological Sciences

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.

Chereddy KK; Her CH; Comune M; Moia C; Lopes A; Porporato PE; Vanacker J; et al, 2014. . 10.1016/j.jconrel.2014.08.016 .

A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects

Lang, N.; Pereira, M.J.; Lee, Y.; Friehs, I.; Vasilyev, N.V.; Feins, E.N.; Ablasser, K.; et al, Science Translational Medicine. 218. 6. 2014. . 10.1126/scitranslmed.3006557 . Science Translational Medicine

Combined Surface Micropatterning and Reactive Chemistry Maximizes Tissue Adhesion with Minimal Inflammation

Pereira, M.J.N.; Sundback, C.A.; Lang, N.; Cho, W.K.; Pomerantseva, I.; Ouyang, B.; Tao, S.L.; et al, Advanced Healthcare Materials. 565 - 571. 4. 3. 2014. . 10.1002/adhm.201300264 . Advanced Healthcare Materials

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial

Gomes, R.S.M.; Neves, R.P.D.; Cochlin, L.; Lima, A.; Carvalho, R.; Korpisalo, P.; Dragneva, G.; et al, ACS Nano. 3362 - 3372. 4. 7. 2013. . 10.1021/nn400171w . ACS Nano

Antifungal activity of dental resins containing amphotericin B-conjugated nanoparticles

Lino, M.M.; Paulo, C.S.O.; Vale, A.C.; Vaz, M.F.; Ferreira, L.S., Dental Materials. 10. 29. 2013. . 10.1016/ . Dental Materials

Boron Nitride Nanotube-Mediated Stimulation of Cell Co-Culture on Micro-Engineered Hydrogels

Ricotti, L.; Fujie, T.; Vazão, H.; Ciofani, G.; Marotta, R.; Brescia, R.; Filippeschi, C.; et al, PLoS ONE. 8. 8. 2013. . 10.1371/journal.pone.0071707 . PLoS ONE

A highly tunable biocompatible and multifunctional biodegradable elastomer

Pereira, M.J.N.; Ouyang, B.; Sundback, C.A.; Lang, N.; Friehs, I.; Mureli, S.; Pomerantseva, I.; et al, Advanced Materials. 1209 - 1215. 8. 25. 2013. . 10.1002/adma.201203824 . Advanced Materials

Differential internalization of amphotericin B - Conjugated nanoparticles in human cells and the expression of heat shock protein 70

Paulo, C.S.O.; Lino, M.M.; Matos, A.A.; Ferreira, L.S., Biomaterials. 5281 - 5293. 21. 34. 2013. . 10.1016/j.biomaterials.2013.03.048 . Biomaterials

Nanoparticles and surfaces presenting antifungal, antibacterial and antiviral properties

Botequim, D.; Maia, J.; Lino, M.M.F.; Lopes, L.M.F.; Simões, P.N.; Ilharco, L.M.; Ferreira, L., Langmuir. 7646 - 7656. 20. 28. 2012. . 10.1021/la300948n . Langmuir

Histamine stimulates neurogenesis in the rodent subventricular zone

Bernardino, L.; Eiriz, M.F.; Santos, T.; Xapelli, S.; Grade, S.; Rosa, A.I.; Cortes, L.; et al, Stem Cells. 773 - 784. 4. 30. 2012. . 10.1002/stem.1042 . Stem Cells

Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain

Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragancia, J.; et al, ACS Nano. 10463 - 10474. 12. 6. 2012. . 10.1021/nn304541h . ACS Nano

Proliferation and skeletal myotube formation capability of C2C12 and H9c2 cells on isotropic and anisotropic electrospun nanofibrous PHB scaffolds

Ricotti, L.; Polini, A.; Genchi, G.G.; Ciofani, G.; Iandolo, D.; Vazão, H.; Mattoli, V.; et al, Biomedical Materials. 3. 7. 2012. . 10.1088/1748-6041/7/3/035010 . Biomedical Materials

VEGF-functionalized dextran has longer intracellular bioactivity than VEGF in endothelial cells

Maia, J.; Vazão, H.; Pedroso, D.C.S.; Jesus, C.S.H.; Brito, R.M.M.; Grãos, M.; Gil, M.H.; Ferreira, L., Biomacromolecules. 2906 - 2916. 9. 13. 2012. . 10.1021/bm3009268 . Biomacromolecules

Nanomedicine boosts neurogenesis: New strategies for brain repair

Santos, T.; Maia, J.; Agasse, F.; Xapelli, S.; Ferreira, L.; Bernardino, L., Integrative Biology (United Kingdom). 973 - 981. 9. 4. 2012. . 10.1039/c2ib20129a . Integrative Biology (United Kingdom)

Histamine modulates microglia function.

Ferreira R; Santos T; Gonçalves J; Baltazar G; Ferreira L; Agasse F; Bernardino L, 2012. . 10.1186/1742-2094-9-90 .

Nanoparticles for intracellular-targeted drug delivery

Paulo, C.S.O.; Pires Das Neves, R.; Ferreira, L.S., Nanotechnology. 49. 22. 2011. . 10.1088/0957-4484/22/49/494002 . Nanotechnology

Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction

Kraehenbuehl, T.P.; Ferreira, L.S.; Hayward, A.M.; Nahrendorf, M.; van der Vlies, A.J.; Vasile, E.; Weissleder, R.; Langer, R.; Hubbell, J.A., Biomaterials. 1102 - 1109. 4. 32. 2011. . 10.1016/j.biomaterials.2010.10.005 . Biomaterials

Three-dimensional biomaterials for the study of human pluripotent stem cells

Kraehenbuehl, T.P.; Langer, R.; Ferreira, L.S., Nature Methods. 731 - 736. 9. 8. 2011. . 10.1038/nmeth.1671 . Nature Methods

Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles

Maia, J.; Santos, T.; Aday, S.; Agasse, F.; Cortes, L.; Malva, J.O.; Bernardino, L.; Ferreira, L., ACS Nano. 97 - 106. 1. 5. 2011. . 10.1021/nn101724r . ACS Nano

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells

Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L., PLoS ONE. 1. 6. 2011. . 10.1371/journal.pone.0016114 . PLoS ONE

Towards the maturation and characterization of smooth muscle cells derived from human embryonic stem cells

Vazão, H.; das Neves, R.P.; Grãos, M.; Ferreira, L., PLoS ONE. 3. 6. 2011. . 10.1371/journal.pone.0017771 . PLoS ONE

Sensing the cardiac environment: Exploiting cues for regeneration

Pereira, M.J.N.; Carvalho, I.F.; Karp, J.M.; Ferreira, L.S., Journal of Cardiovascular Translational Research. 616 - 630. 5. 4. 2011. . 10.1007/s12265-011-9299-6 . Journal of Cardiovascular Translational Research

Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells.

Levenberg, S.; Ferreira, L.S.; Chen-Konak, L.; Kraehenbuehl, T.P.; Langer, R., Nature protocols. 1115 - 1126. 6. 5. 2010. . 10.1038/nprot.2010.31 . Nature protocols

Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds.

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Stem cell-based therapies for heart regeneration: What did the bench teach us?

Ferreira, L.; Pedroso, D.C.S.; Vazão, H.; Gomes, R.S.M., Cardiovascular and Hematological Disorders - Drug Targets. 173 - 185. 3. 10. 2010. . Cardiovascular and Hematological Disorders - Drug Targets

Antifungal nanoparticles and surfaces

Paulo, C.S.O.; Vidal, M.; Ferreira, L.S., Biomacromolecules. 2810 - 2817. 10. 11. 2010. . 10.1021/bm100893r . Biomacromolecules

Non-leaching surfaces capable of killing microorganisms on contact

Ferreira, L.; Zumbuehl, A., Journal of Materials Chemistry. 7796 - 7806. 42. 19. 2009. . 10.1039/b905668h . Journal of Materials Chemistry

Nanoparticles as tools to study and control stem cells

Ferreira, L., Journal of Cellular Biochemistry. 746 - 752. 4. 108. 2009. . 10.1002/jcb.22303 . Journal of Cellular Biochemistry

Cell-responsive hydrogel for encapsulation of vascular cells

Kraehenbuehl, T.P.; Ferreira, L.S.; Zammaretti, P.; Hubbell, J.A.; Langer, R., Biomaterials. 4318 - 4324. 26. 30. 2009. . 10.1016/j.biomaterials.2009.04.057 . Biomaterials

A biodegradable and biocompatible gecko-inspired tissue adhesive

Mahdavi, A.; Ferreira, L.; Sundback, C.; Nichol, J.W.; Chan, E.P.; Carter, D.J.D.; Bettinger, C.J.; et al, Proceedings of the National Academy of Sciences of the United States of America. 2307 - 2312. 7. 105. 2008. . 10.1073/pnas.0712117105 . Proceedings of the National Academy of Sciences of the United States of America

New Opportunities: The Use of Nanotechnologies to Manipulate and Track Stem Cells

Ferreira, L.; Karp, J.M.; Nobre, L.; Langer, R., Cell Stem Cell. 136 - 146. 2. 3. 2008. . 10.1016/j.stem.2008.07.020 . Cell Stem Cell

Human embryoid bodies containing nano- And microparticulate delivery vehicles

Ferreira, L.; Squier, T.; Park, H.; Choe, H.; Kohane, D.S.; Langer, R., Advanced Materials. 2285 - 2291. 12. 20. 2008. . 10.1002/adma.200702404 . Advanced Materials

Intracellular delivery of core-shell fluorescent silica nanoparticles

Fuller, J.E.; Zugates, G.T.; Ferreira, L.S.; Ow, H.S.; Nguyen, N.N.; Wiesner, U.B.; Langer, R.S., Biomaterials. 1526 - 1532. 10. 29. 2008. . 10.1016/j.biomaterials.2007.11.025 . Biomaterials

Antifungal hydrogels

Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al, Proceedings of the National Academy of Sciences of the United States of America. 12994 - 12998. 32. 104. 2007. . 10.1073/pnas.0705250104 . Proceedings of the National Academy of Sciences of the United States of America

Synthesis and characterization of photocurable elastomers from poly(glycerol-co-sebacate)

Nijst, C.L.E.; Bruggeman, J.P.; Karp, J.M.; Ferreira, L.; Zumbuehl, A.; Bettinger, C.J.; Langer, R., Biomacromolecules. 3067 - 3073. 10. 8. 2007. . 10.1021/bm070423u . Biomacromolecules

Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells

Ferreira, L.S.; Gerecht, S.; Fuller, J.; Shieh, H.F.; Vunjak-Novakovic, G.; Langer, R., Biomaterials. 2706 - 2717. 17. 28. 2007. . 10.1016/j.biomaterials.2007.01.021 . Biomaterials

Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle-like cells and form vascular networks in vivo

Ferreira, L.S.; Gerecht, S.; Shieh, H.F.; Watson, N.; Rupnick, M.A.; Dallabrida, S.M.; Vunjak-Novakovic, G.; Langer, R., Circulation Research. 286 - 294. 3. 101. 2007. . 10.1161/CIRCRESAHA.107.150201 . Circulation Research

Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells

Gerecht, S.; Burdick, J.A.; Ferreira, L.S.; Townsend, S.A.; Langer, R.; Vunjak-Novakovic, G., Proceedings of the National Academy of Sciences of the United States of America. 11298 - 11303. 27. 104. 2007. . 10.1073/pnas.0703723104 . Proceedings of the National Academy of Sciences of the United States of America

Structural analysis of dextran-based hydrogels obtained chemoenzymatically

Ferreira, L.; Figueirecio, M.M.; Gil, M.H.; Ramos, M.A., Journal of Biomedical Materials Research - Part B Applied Biomaterials. 55 - 64. 1. 77. 2006. . 10.1002/jbm.b.30394 . Journal of Biomedical Materials Research - Part B Applied Biomaterials

Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates

Khademhosseini, A.; Ferreira, L.; Blumling III, J.; Yeh, J.; Karp, J.M.; Fukuda, J.; Langer, R., Biomaterials. 5968 - 5977. 36. 27. 2006. . 10.1016/j.biomaterials.2006.06.035 . Biomaterials

Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro

Karp, J.M.; Ferreira, L.S.; Khademhosseini, A.; Kwon, A.H.; Yeh, J.; Langer, R.S., Stem Cells. 835 - 843. 4. 24. 2006. . 10.1634/stemcells.2005-0383 . Stem Cells

Synthesis and characterization of new injectable and degradable dextran-based hydrogels

Maia, J.; Ferreira, L.; Carvalho, R.; Ramos, M.A.; Gil, M.H., Polymer. 9604 - 9614. 23. 46. 2005. . 10.1016/j.polymer.2005.07.089 . Polymer

Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests

Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A., Polymer. 9840 - 9850. 23. 46. 2005. . 10.1016/j.polymer.2005.08.033 . Polymer

Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels

Ferreira, L.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S., Biomaterials. 4707 - 4716. 23. 26. 2005. . 10.1016/j.biomaterials.2004.11.051 . Biomaterials

Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels

Ferreira, L.; Rafael, A.; Lamghari, M.; Barbosa, M.A.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S., Journal of Biomedical Materials Research - Part A. 584 - 596. 3. 68. 2004. . Journal of Biomedical Materials Research - Part A

Influence of different silica derivatives in the immobilization and stabilization of a Bacillus licheniformis protease (Subtilisin Carlsberg)

Ferreira, L.; Ramos, M.A.; Dordick, J.S.; Gil, M.H., Journal of Molecular Catalysis B: Enzymatic. 189 - 199. 4-6. 21. 2003. . 10.1016/S1381-1177(02)00223-0 . Journal of Molecular Catalysis B: Enzymatic

Enzymatic synthesis of dextran-containing hydrogels

Ferreira, L.; Gil, M.H.; Dordick, J.S.; Carvalho, R., Biomaterials. 3957 - 3967. 19. 23. 2002. . 10.1016/S0142-9612(02)00132-1 . Biomaterials

Biocatalytic polytransesterification of inulin with divinyladipate

Ferreira, L.; Gil, M.H.; Carvalho, R.; Geraldes, C.F.G.C.; Kim, D.-Y.; Dordick, J.S., Chemistry of Materials. 4009 - 4011. 10. 14. 2002. . 10.1021/cm020393w . Chemistry of Materials

Exquisite regioselectivity and increased transesterification activity of an immobilized Bacillus subtilis protease

Ferreira, L.; Ramos, M.A.; Gil, M.H.; Dordick, J.S., Biotechnology Progress. 986 - 993. 5. 18. 2002. . 10.1021/bp0255457 . Biotechnology Progress

Design of a drug-delivery system based on polyacrylamide hydrogels. Evaluation of structural properties

Ferreira, Lino, Chemical educator. 2001. . 10.1007/s00897010461a . Chemical educator

Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values

Ferreira, L.; Vidal, M.M.; Gil, M.H., International Journal of Pharmaceutics. 169 - 180. 2. 194. 2000. . 10.1016/S0378-5173(99)00375-0 . International Journal of Pharmaceutics

Preparation and characterization of gels based on sucrose modified with glycidyl methacrylate

Ferreira, L.; Vidal, M.M.; Geraldes, C.F.G.C.; Gil, M.H., Carbohydrate Polymers. 15 - 24. 1. 41. 2000. . 10.1016/S0144-8617(99)00064-8 . Carbohydrate Polymers

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