Mariana Raquel Antunes Colaço

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PhD Student


Mariana Colaço completed in 2016 the Bachelor Degree in Biochemistry (University of Coimbra, Faculty of Science and Technology), and the Master Degree in Pharmaceutical Biotechnology in 2018 with a dissertation entitled "Development of nanosized glucan particles with immunostimulatory function as a delivery system for curcumin" (University of Coimbra, Faculty of Pharmacy). Currently, she is a PhD student in Pharmaceutical Sciences (Pharmaceutical Technology) in Faculty of Pharmacy (University of Coimbra) working on the project: "Designing cationic polymer-DNA complexes for nasal immunization against SARS-CoV-2". Since the completion of her MsD (2018), Mariana Colaço has published 2 articles as first author and 4 articles as co-author. She participated as a Master Student Fellow in 2 projects: an international PROSAFE project (GoNanoBioMat) and a project for the development of a therapeutic vaccine against chronic hepatitis B using glucan based adjuvant nanocarriers. In her professional activities has interacted with 15 collaborators/ co-authorship of scientific papers. In her curriculum Ciência Vitae the most frequent terms in the context of scientific and technological output are: Polymeric; nanoparticles; curcumin; glucan; immunotoxicity; anti-inflammatory; therapeutic; safe-by-design; in vitro; immune response.


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Information about journal articles, updated at 26-06-2022, from platform CIÊNCIAVITAE.

Unravelling the Immunotoxicity of Polycaprolactone Nanoparticles—Effects of Polymer Molecular Weight, Hydrolysis, and Blends

Jesus, Sandra; Bernardi, Natalia; da Silva, Jessica; Colaço, Mariana; Panão Costa, João; Fonte, Pedro; Borges, Olga, Chemical Research in Toxicology. 2819 - 2833. 11. 33. 2020. . 10.1021/acs.chemrestox.0c00208 . published Chemical Research in Toxicology

Airborne environmental fine particles induce intense inflammatory response regardless of the absence of heavy metal elements

Colaço, Mariana; Duarte, Alana; Zuzarte, Mónica; Costa, Benilde F.O.; Borges, Olga, Ecotoxicology and Environmental Safety. 195. 2020. . 10.1016/j.ecoenv.2020.110500 . published Ecotoxicology and Environmental Safety

Safe-by-Design of Glucan Nanoparticles: Size Matters When Assessing the Immunotoxicity

Colaço, Mariana; Marques, Ana P.; Jesus, Sandra; Duarte, Alana; Borges, Olga, Chemical Research in Toxicology. 2020. . 10.1021/acs.chemrestox.9b00467 . published Chemical Research in Toxicology

Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility

Jesus, Sandra; Marques, Ana Patrícia; Duarte, Alana; Soares, Edna; Costa, João Panão; Colaço, Mariana; Schmutz, Mélanie; et al, Frontiers in Bioengineering and Biotechnology. 100. 8. 2020. . 10.3389/fbioe.2020.00100 . published Frontiers in Bioengineering and Biotechnology

Poly(D,L-Lactic Acid) Nanoparticle Size Reduction Increases its Immunotoxicity

Silva, Jessica; Jesus, Sandra; Benardi, Natália; Colaço, Mariana; Borges, Olga, Frontiers in Bioengineering and Biotechnology. 2019. . published Frontiers in Bioengineering and Biotechnology

All projects

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Information of exclusive responsibility of the researcher 26-06-2022 , from platform CIÊNCIAVITAE.

2021/12/01 - 2022/12/01

Vacina Intranasal genética contra o COVID: estudos de imunização em murganhos



Universidade de Coimbra Faculdade de Farmácia

Funders: Gilead Sciences Lda

2019/11/20 - 2020/11/19

Hepatitis B therapeutic vaccine: Production of glucan-based nanoparticles towards selective delivery hepatitis B antigens to immune cells to induce antiviral activity


Research Fellow

Funders: Fundação para a Ciência e a Tecnologia

2017/04/01 - 2019/06/30

Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions


Research Fellow

Funders: Fundação para a Ciência e a Tecnologia

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