Publications
Information about journal articles, updated at 13-10-2024, from platform CIÊNCIAVITAE.
Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism
Amorim, Ricardo; Magalhães, Carina C.; Benfeito, Sofia; Cagide, Fernando; Tavares, Ludgero C.; Santos, Katia; Sardão, Vilma A.; et al, Biochemical Pharmacology. 219. 2024. http://dx.doi.org/10.1016/j.bcp.2023.115953 . 10.1016/j.bcp.2023.115953 . Biochemical Pharmacology
Decreasing the Burden of Non-Alcoholic Fatty Liver Disease: from Therapeutic Targets to Drug Discovery Opportunities
Amorim, Ricardo; Chavarria, Daniel; Soares, Pedro; Benfeito, Sofia; Cagide, Fernando; Teixeira, José; Oliveira, Paulo; Borges, Fernanda, Medicinal Research Reviews. 2024. submitted Medicinal Research Reviews
Age-dependent energy metabolism and transcriptome changes in urine-derived stem cells
Ferreiro, Elisabete; Monteiro, Mariana; Pereira, Francisco; Barroso, Cristina; Egas, Conceição; Macedo, Paula; Valero, Jorge; Sardão, Vilma A.; Oliveira, Paulo J., Mechanisms of Ageing and Development. 218. 2024. http://dx.doi.org/10.1016/j.mad.2024.111912 . 10.1016/j.mad.2024.111912 . Mechanisms of Ageing and Development
<i>Acrocomia aculeata</i> associated with doxorubicin: cardioprotection and anticancer activity
Monteiro-Alfredo, Tamaeh; dos Santos, Jessica Maurino; Antunes, Katia Avila; Cunha, Janielle; Baldivia, Debora da Silva; Pires, Ana Salome; Marques, Ines; et al, Frontiers in Pharmacology. 2023. https://publons.com/wos-op/publon/61325685/ . 10.3389/FPHAR.2023.1223933 . Frontiers in Pharmacology
Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions
Cavaleiro, Carla; Afonso, Gonçalo J. M.; Oliveira, Paulo J.; Valero, Jorge; Mota, Sandra I.; Ferreiro, Elisabete, Frontiers in Molecular Neuroscience. 16. 2023. http://dx.doi.org/10.3389/fnmol.2023.1229728 . 10.3389/fnmol.2023.1229728 . Frontiers in Molecular Neuroscience
Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model
Pereira, Susana P.; Diniz, Mariana S.; Tavares, Ludgero C.; Cunha-Oliveira, Teresa; Li, Cun; Cox, Laura A.; Nijland, Mark J.; Nathanielsz, Peter W.; Oliveira, Paulo J., International Journal of Molecular Sciences. 20. 24. 2023. http://dx.doi.org/10.3390/ijms242015192 . 10.3390/ijms242015192 . International Journal of Molecular Sciences
Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer activity
Monteiro-Alfredo, Tamaeh; dos Santos, Jéssica Maurino; Antunes, Kátia Ávila; Cunha, Janielle; da Silva Baldivia, Debora; Pires, Ana Salomé; Marques, Inês; et al, Frontiers in Pharmacology. 14. 2023. http://dx.doi.org/10.3389/fphar.2023.1223933 . 10.3389/fphar.2023.1223933 . Frontiers in Pharmacology
Metabolic mitochondrial alterations prevail in the female rat heart 8¿weeks after exercise cessation
Tocantins, Carolina; Martins, João D.; Rodrigues, Óscar M.; Grilo, Luís F.; Diniz, Mariana S.; Stevanovic-Silva, Jelena; Beleza, Jorge; et al, European Journal of Clinical Investigation. 11. 53. 2023. http://dx.doi.org/10.1111/eci.14069 . 10.1111/eci.14069 . European Journal of Clinical Investigation
Second International Pulmonary Hypertension/Heart Failure Symposium—Structural heart disease, right ventricular dysfunction, and stem cell therapy: The European Pediatric Pulmonary Vascular Disease Network
Chouvarine, Philippe; Hysko, Klea; Chan, Stephen Y.; Oliveira, Paulo; Maron, Bradley A.; Kourembanas, Stella; Hansmann, Georg, Pulmonary Circulation. 1. 13. 2023. http://dx.doi.org/10.1002/pul2.12175 . 10.1002/pul2.12175 . Pulmonary Circulation
Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress
Luís F. Grilo; João D. Martins; Mariana S. Diniz; Carolina Tocantins; Chiara H. Cavallaro; Inês Baldeiras; Teresa Cunha-Oliveira; et al, Clinical Science. 1347 - 1372. 17. 137. 2023. https://doi.org/10.1042/CS20230048 . 10.1042/CS20230048 . Clinical Science
Real-time OXPHOS capacity analysis in wounded skin from diabetic mice: A pilot study
Aryane Cruz Oliveira Pinho; Diana Santos; Paulo J. Oliveira; Ermelindo Carreira Leal; Eugenia Carvalho, European Journal of Clinical Investigation. 2023. https://doi.org/10.1111/eci.14128 . 10.1111/eci.14128 . European Journal of Clinical Investigation
TRAP1 Is Expressed in Human Retinal Pigment Epithelial Cells and Is Required to Maintain their Energetic Status
Inês Ramos Rego; Daniela Silverio; Maria Isabel Eufrásio; Sandra Sofia Pinhanços; Bruna Lopes da Costa; José Carlos Santos Teixeira; Hugo Fernandes; et al, Antioxidants. 2023. https://www.mdpi.com/2076-3921/12/2/381 . 10.3390/antiox12020381 . Antioxidants
Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Sofia Benfeito; Carlos Fernandes; Daniel Chavarria; Sandra Barreiro; Fernando Cagide; Lisa Sequeira; José Teixeira; et al, Journal of Medicinal Chemistry. 2023. https://doi.org/10.1021/acs.jmedchem.2c01630 . 10.1021/acs.jmedchem.2c01630 . Journal of Medicinal Chemistry
Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models
Diana Sousa; Mariana Rocha; Andreia Marreiros Amaro; Marcos Divino Ferreira-Junior; Keilah Valéria Naves Cavalcante; Tamaeh Monteiro-Alfredo; Tamaeh Monteiro Alfredo; Cátia Barra; et al, Nutrients. 2023. https://www.mdpi.com/2072-6643/15/5/1281 . 10.3390/nu15051281 . Nutrients
Exploring Iberian Peninsula Lamiaceae as Potential Therapeutic Approaches in Wound Healing
Mário P. Marques; Laura Mendonça; Beatriz G. Neves; Carla Varela; Paulo Oliveira; Célia Cabral, Pharmaceuticals. 2023. https://doi.org/10.3390/ph16030347 . 10.3390/ph16030347 . Pharmaceuticals
Gestational Exercise Antagonises the Impact of Maternal High-Fat High-Sucrose Diet on Liver Mitochondrial Alterations and Quality Control Signalling in Male Offspring
Jelena Stevanovic-Silva; Jorge Beleza; Pedro Coxito; Paulo J. Oliveira; António Ascensão; José Magalhães, International Journal of Environmental Research and Public Health. 2023. https://doi.org/10.3390/ijerph20021388 . 10.3390/ijerph20021388 . International Journal of Environmental Research and Public Health
<i>Brassica oleracea</i> Var <i>italica</i> by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity
José P. Castelão-Baptista; Sara Valente; Sara Canário; David Oppolzer; A.I.R.N.A.Barros; Carlos Venâncio; Tânia Martins; et al, Nutrients. 2023. https://www.mdpi.com/2072-6643/15/4/924 . 10.3390/nu15040924 . Nutrients
The H9c2(2-1) cell-based sulforhodamine B assay is a non-animal alternative to evaluate municipal wastewater quality over time
Elsa T. Rodrigues; Eduarda Pereira; Paulo J. Oliveira; Miguel A. Pardal; Rodrigues, Elsa T.; Pereira, Eduarda; Oliveira, Paulo J.; Pardal, Miguel A., Environmental Monitoring and Assessment. 11. 195. 2023. https://doi.org/10.1007/s10661-023-12017-8 . 10.1007/s10661-023-12017-8 . Environmental Monitoring and Assessment
Drug discovery and amyotrophic lateral sclerosis: Emerging challenges and therapeutic opportunities
Soares, Pedro; Chavarria, Daniel; Silva, Catia; Silva, Filomena S.G.; Oliveira, Paulo J.; Borges, Fernanda, Ageing Research Reviews. 83. 2023. http://dx.doi.org/10.1016/j.arr.2022.101790 . 10.1016/j.arr.2022.101790 . Ageing Research Reviews
Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease
Diniz, Mariana S; Hiden, Ursula; Falcão-Pires, Inês; Oliveira, Paulo J; Sobrevia, Luis; Pereira, Susana P; Diniz, Mariana S.; Oliveira, Paulo J.; Pereira, Susana P., Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 8. 1869. 2023. http://hdl.handle.net/10316/108720 . https://doi.org/10.1016/j.bbadis.2023.166834 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Reply to the Comment on “1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis”
Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al, Pharmacological Research. 191. 2023. http://dx.doi.org/10.1016/j.phrs.2022.106623 . 10.1016/j.phrs.2022.106623 . published Pharmacological Research
From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria
Amorim, Ricardo; Magalhães, Carina C.; Borges, Fernanda; Oliveira, Paulo J.; Teixeira, José, Biology. 4. 12. 2023. http://dx.doi.org/10.3390/biology12040595 . 10.3390/biology12040595 . Biology
Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCd Activator
Bessa, Cláudia; Loureiro, Joana B.; Barros, Matilde; Isca, Vera M. S.; Sardão, Vilma A.; Oliveira, Paulo J.; Bernardino, Raquel L.; et al, International Journal of Molecular Sciences. 6. 24. 2023. http://dx.doi.org/10.3390/ijms24065710 . 10.3390/ijms24065710 . International Journal of Molecular Sciences
Amyotrophic Lateral Sclerosis: When Nerve Cells Run Out of Power
Quatorze, Marta; Silva, Filomena; Duarte, Ana I.; Cardoso, João; Caetano, Carolina; Ramalho-Santos, João; Oliveira, Paulo J.; Amaral, Sara Varela, Frontiers for Young Minds. 11. 2023. http://dx.doi.org/10.3389/frym.2023.974736 . 10.3389/frym.2023.974736 . published Frontiers for Young Minds
Maternal obesity and reduced maternal nutrition during fetal development differentially result in altered cardiac transcriptome regulating cardiomyocyte maturation, proliferation, and enlargement at late gestation.
Luís F. Grilo; Susana P. Pereira; Oliveira, Paulo J.; Cun Li; Kenneth Lange; Jeremy P. Glenn ; Kip D. Zimmerman ; Nathanielsz, Peter W.; Cox, Laura A., Cellular and Molecular Life Sciences . 2023. submitted Cellular and Molecular Life Sciences
Evaluation of 6-Hydroxydopamine and Rotenone In Vitro Neurotoxicity on Differentiated SH-SY5Y Cells Using Applied Computational Statistics
Simões, Rui F.; Oliveira, Paulo J.; Oliveira, Teresa Cunha; Pereira, Francisco B.; Rui F. Simões; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, International Journal of Molecular Sciences. 3009 - 3009. 6. 23. 2022. http://hdl.handle.net/10316/103323 . https://doi.org/10.3390/ijms23063009 . International Journal of Molecular Sciences
Mitochondrial and metabolic remodelling in human skin fibroblasts in response to glucose availability
Sónia A. Pinho; Cláudio F. Costa; Cláudia M. Deus; Sonia L. C. Pinho; Inês Miranda-Santos; Gonçalo Afonso; Olivia Bagshaw; et al, The FEBS Journal. 2022. https://doi.org/10.1111/febs.16413 . 10.1111/febs.16413 . The FEBS Journal
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis
Albertini, Claudia; Salerno, Alessandra; Atzeni, Silvia; Uliassi, Elisa; Massenzio, Francesca; Maruca, Annalisa; Rocca, Roberta; et al, ACS Chemical Neuroscience. 2022. http://dx.doi.org/10.1021/acschemneuro.2c00261 . 10.1021/acschemneuro.2c00261 . ACS Chemical Neuroscience
NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells
Emiliano Panieri; Sónia A. Pinho; Gonçalo J. M. Afonso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Luciano Saso, Cells. 2022. https://doi.org/10.3390/cells11152401 . 10.3390/cells11152401 . Cells
Targeting Hydroxybenzoic Acids to Mitochondria as a Strategy to Delay Skin Ageing: An In Vitro Approach
Carlos Fernandes; Fernando Cagide; Jorge Simões; Carlos Pita; Eurico Pereira; Afonso J. C. Videira; Pedro Soares; et al, Molecules. 2022. https://doi.org/10.3390/molecules27196183 . 10.3390/molecules27196183 . Molecules
Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems
Amorim, Ricardo; Simões, Inês C.M.; Teixeira, José; Cagide, Fernando; Potes, Yaiza; Soares, Pedro; Carvalho, Adriana; et al, Redox Biology. 55. 2022. http://dx.doi.org/10.1016/j.redox.2022.102400 . 10.1016/j.redox.2022.102400 . Redox Biology
Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage
Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al, Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine
Effect of a Novel Hydroxybenzoic Acid Based Mitochondria Directed Antioxidant Molecule on Bovine Sperm Function and Embryo Production
João Campos Santos; Carla Cruz Marques; Maria Conceição Baptista; Jorge Pimenta; José Carlos Santos Teixeira; Liliana Montezinho; Fernando Cagide; et al, Animals. 2022. https://www.mdpi.com/2076-2615/12/7/804 . 10.3390/ani12070804 . Animals
The heart of FOIE GRAS and mtFOIE GRAS: fundamental and clinical investigation for training and innovation in non-alcoholic fatty liver disease
Paulo J Oliveira, European Heart Journal. 2022. https://doi.org/10.1093/eurheartj/ehab399 . 10.1093/eurheartj/ehab399 . European Heart Journal
The Role of Glucosinolates from Cruciferous Vegetables (Brassicaceae) in Gastrointestinal Cancers: From Prevention to Therapeutics
Melim, Catarina; Lauro, Maria R.; Pires, Isabel M.; Oliveira, Paulo J.; Cabral, Célia; Catarina Melim; Maria R. Lauro; et al, Pharmaceutics. 2022. http://hdl.handle.net/10316/103454 . https://doi.org/10.3390/pharmaceutics14010190 . Pharmaceutics
Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations
Teresa Cunha-Oliveira; Daniela Franco Silva; Luis Segura; Inês Baldeiras; Ricardo Marques; Tatiana Rosenstock; Paulo J. Oliveira; Filomena S. G. Silva, European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13798 . 10.1111/eci.13798 . European Journal of Clinical Investigation
Modulation of cellular redox environment as a novel therapeutic strategy for Parkinson's disease
Cláudia M. Deus; José Teixeira; Nuno Raimundo; Paolo Tucci; Fernanda Borges; Luciano Saso; Paulo J. Oliveira, European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13820 . 10.1111/eci.13820 . European Journal of Clinical Investigation
Bioenergetic remodeling in the pathophysiology and treatment of nonalcoholic fatty liver disease
Anabela Marisa Azul; Martin Winter; Daniel Silva; Liljana Georgievska; Paulo J. Oliveira, European Journal of Clinical Investigation. 2022. https://doi.org/10.1111/eci.13749 . 10.1111/eci.13749 . European Journal of Clinical Investigation
1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis
Alves-Silva, Jorge M.; Zuzarte, Mónica; Marques, Carla; Viana, Sofia; Preguiça, Inês; Baptista, Rui; Ferreira, Cátia; et al, Pharmacological Research. 180. 2022. http://dx.doi.org/10.1016/j.phrs.2022.106151 . 10.1016/j.phrs.2022.106151 . Pharmacological Research
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Afonso, Marta B.; Islam, Tawhidul; Magusto, Julie; Amorim, Ricardo; Lenoir, Véronique; Simões, Rui F.; Teixeira, José; et al, Hepatology. 1319 - 1334. 4. 77. 2022. http://dx.doi.org/10.1002/hep.32756 . 10.1002/hep.32756 . Hepatology
Boosting caffeic acid performance as antioxidant and monoamine oxidase B/catechol-O-methyltransferase inhibitor
Chavarria, Daniel; Benfeito, Sofia; Soares, Pedro; Lima, Carla; Garrido, Jorge; Serrão, Paula; Soares-da-Silva, Patrício; et al, European Journal of Medicinal Chemistry. 243. 2022. http://dx.doi.org/10.1016/j.ejmech.2022.114740 . 10.1016/j.ejmech.2022.114740 . European Journal of Medicinal Chemistry
Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond
Luís F. Grilo; Carolina Tocantins; Mariana S. Diniz; Rodrigo Mello Gomes; Paulo J. Oliveira; Paulo Matafome; Susana P. Pereira, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13625 . 10.1111/eci.13625 . European Journal of Clinical Investigation
Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis
Carlos Fernandes; Afonso J. C. Videira; Caroline D. Veloso; Sofia Benfeito; Pedro Soares; João D. Martins; Beatriz Gonçalves; et al, Biomolecules. 1605 - 1605. 11. 11. 2021. https://doi.org/10.3390/biom11111605 . 10.3390/biom11111605 . Biomolecules
Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine
Rui F. Simões; Rute Pino; Maurício Moreira-Soares; Jaromira Kovarova; Jiri Neuzil; Rui Travasso; Paulo J. Oliveira; Teresa Cunha-Oliveira; Francisco B. Pereira, The FASEB Journal. 12. 35. 2021. https://doi.org/10.1096/fj.202100899R . 10.1096/fj.202100899R . The FASEB Journal
Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
Daniel Chavarria; Ophelie DA SILVA; Sofia Benfeito; Sandra Barreiro; Jorge Garrido; Cagide-Fagín; Pedro Soares; et al, Antioxidants. 2021. https://www.mdpi.com/2076-3921/10/2/329 . 10.3390/antiox10020329 . Antioxidants
Glutaminolysis is a metabolic route essential for survival and growth of prostate cancer cells and a target of 5a-dihydrotestosterone regulation
Henrique J. Cardoso; Marília I. Figueira; Cátia V. Vaz; Tiago M. A. Carvalho; Luís A. Brás; Patrícia A. Madureira; Paulo J. Oliveira; Vilma A. Sardão; Sílvia Socorro, Cellular Oncology. 2021. https://doi.org/10.1007/s13402-020-00575-9 . 10.1007/s13402-020-00575-9 . Cellular Oncology
H9c2(2-1)-based sulforhodamine B assay as a possible alternative in vitro platform to investigate effluent and metals toxicity on fish
Elsa T. Rodrigues; Miguel A. Pardal; Eduarda Pereira; Joana F. Monteiro; Ana C. Certal; Paulo J. Oliveira, Chemosphere. 2021. https://doi.org/10.1016/j.chemosphere.2021.130009 . 10.1016/j.chemosphere.2021.130009 . Chemosphere
Afrostyrax lepidophyllus Mildbr. and Monodora myristica (Gaertn.) Dunal Extracts Decrease Doxorubicin Cytotoxicity on H9c2 Cardiomyoblasts
Bruno M. Moukette; José P. Castelão-Baptista; Luciana Ferreira; Ana M. Silva; Rui F. Simões; Célia Cabral; Constant A. Pieme; et al, Evidence-Based Complementary and Alternative Medicine. 2021. https://doi.org/10.1155/2021/8858165 . 10.1155/2021/8858165 . Evidence-Based Complementary and Alternative Medicine
Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research
Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira, Food and Chemical Toxicology. 111967 - 111967. 149. 2021. https://doi.org/10.1016/j.fct.2021.111967 . 10.1016/j.fct.2021.111967 . Food and Chemical Toxicology
A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients
Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; José Teixeira; Rui F. Simões; Fernando Cagide; Sofia Benfeito; et al, Redox Biology. 102037 - 102037. 45. 2021. https://doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . Redox Biology
Exposure to marine benthic dinoflagellate toxins may lead to mitochondrial dysfunction
Varela, Ana T.; Neves, Raquel A.F.; Nascimento, Silvia M.; Oliveira, Paulo J.; Pardal, Miguel A.; Rodrigues, Elsa T.; Moreno, António J., Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 240. 2021. http://dx.doi.org/10.1016/j.cbpc.2020.108937 . 10.1016/j.cbpc.2020.108937 . published Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts
Teixeira, José; Basit, Farhan; Willems, Peter H.G.M.; Wagenaars, Jori A.; van de Westerlo, Els; Amorim, Ricardo; Cagide, Fernando; et al, Free Radical Biology and Medicine. 314 - 324. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.023 . 10.1016/j.freeradbiomed.2020.12.023 . Free Radical Biology and Medicine
Carbon Monoxide-Neuroglobin Axis Targeting Metabolism Against Inflammation in BV-2 Microglial Cells
Dias-Pedroso, Daniela; Ramalho, José S.; Sardão, Vilma A.; Jones, John G.; Romão, Carlos C.; Oliveira, Paulo J.; Vieira, Helena L.A., Molecular Neurobiology. 2021. http://dx.doi.org/10.1007/s12035-021-02630-4 . 10.1007/s12035-021-02630-4 . Molecular Neurobiology
Maternal high-fat high-sucrose diet and gestational exercise modulate hepatic fat accumulation and liver mitochondrial respiratory capacity in mothers and male offspring
Stevanovic-Silva, Jelena; Beleza, Jorge; Coxito, Pedro; Pereira, Susana; Rocha, Hugo; Gaspar, Tiago Bordeira; Gärtner, Fátima; et al, Metabolism. 116. 2021. http://dx.doi.org/10.1016/j.metabol.2021.154704 . 10.1016/j.metabol.2021.154704 . Metabolism
MOTS-c reduces myostatin and muscle atrophy signaling
Kumagai, Hiroshi; Coelho, Ana Raquel; Wan, Junxiang; Mehta, Hemal; Yen, Kelvin; Huang, Amy; Zempo, Hirofumi; et al, American Journal of Physiology-Endocrinology and Metabolism. 2021. http://dx.doi.org/10.1152/ajpendo.00275.2020 . 10.1152/ajpendo.00275.2020 . American Journal of Physiology-Endocrinology and Metabolism
Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells
Amorim, Ricardo; Simões, Inês; Veloso, Caroline; Marques-Carvalho, Adriana; Simões, Rui; Pereira, Francisco; Thiel, Theresa; et al, Nutrients. 5. 13. 2021. http://dx.doi.org/10.3390/nu13051723 . 10.3390/nu13051723 . Nutrients
Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy
Kendall B. Wallace; Vilma A. Sardão; Paulo J. Oliveira, Circulation Research. 926 - 941. 7. 126. 2020. https://doi.org/10.1161/CIRCRESAHA.119.314681 . 10.1161/CIRCRESAHA.119.314681 . Circulation Research
Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine
Guida Bento; Aygul K. Shafigullina; Albert A. Rizvanov; Vilma A. Sardão; Maria Paula Macedo; Paulo J. Oliveira, Cells. 573 - 573. 3. 9. 2020. https://doi.org/10.3390/cells9030573 . 10.3390/cells9030573 . Cells
Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing
Susana Ponte; Lara Carvalho; Maria Gagliardi; Isabel Campos; Paulo J. Oliveira; António Jacinto, Biology Open. 2020. https://doi.org/10.1242/bio.048629 . 10.1242/bio.048629 . Biology Open
Cell quality control mechanisms maintain stemness and differentiation potential of P19 embryonic carcinoma cells
Magalhães-Novais, Silvia; Bermejo-Millo, Juan C.; Loureiro, Rute; Mesquita, Katia A.; Domingues, M. Rosário; Maciel, Elisabete; Melo, Tânia; et al, Autophagy. 313 - 333. 2. 16. 2020. http://dx.doi.org/10.1080/15548627.2019.1607694 . 10.1080/15548627.2019.1607694 . Autophagy
Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention
Teresa Cunha-Oliveira; Liliana Montezinho; Catarina Mendes; Omidreza Firuzi; Luciano Saso; Paulo J. Oliveira; Filomena S. G. Silva; Jos L. Quiles, Oxidative Medicine and Cellular Longevity. 2020. https://doi.org/10.1155/2020/5021694 . 10.1155/2020/5021694 . Oxidative Medicine and Cellular Longevity
Rat cardiomyocyte H9c2(2-1)-based sulforhodamine B assay as a promising in vitro method to assess the biological component of effluent toxicity
Rodrigues, Elsa T.; Nascimento, Susana F.; Moreno, Maria Joao; Oliveira, Paulo J.; Pardal, Miguel A., Journal of Environmental Sciences. 2020. https://publons.com/wos-op/publon/32227194/ . 10.1016/J.JES.2020.04.029 . Journal of Environmental Sciences
Dihydroorotate dehydrogenase inhibitors in SARS-CoV-2 infection
Ana R. Coelho; Paulo J. Oliveira, European Journal of Clinical Investigation. 2020. https://doi.org/10.1111/eci.13366 . 10.1111/eci.13366 . European Journal of Clinical Investigation
Publicly stressing the role of mitochondria in NAFLD with(in) a sports event
Mireia Alemany-Pagès; Rui Tavares; Sara Varela Amaral; Ana Teresa Barros-Viegas; Paulo J. Oliveira; João Ramalho-Santos; Anabela Marisa Azul, European Journal of Clinical Investigation. 2020. https://doi.org/10.1111/eci.13234 . 10.1111/eci.13234 . European Journal of Clinical Investigation
Mitochondria¿Lysosome Crosstalk: From Physiology to Neurodegeneration
Deus, Cláudia M.; Yambire, King Faisal; Oliveira, Paulo J.; Raimundo, Nuno, Trends in Molecular Medicine. 71 - 88. 1. 26. 2020. http://dx.doi.org/10.1016/j.molmed.2019.10.009 . 10.1016/j.molmed.2019.10.009 . Trends in Molecular Medicine
Mitochondrial impairment and cytotoxicity effects induced by the marine epibenthic dinoflagellate Coolia malayensis
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Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid
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SULFATION PATHWAYS: Potential benefits of a sulfated resveratrol derivative for topical application.
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Mitochondria in chronic liver disease
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Branco, A.F., Cardiovascular Toxicology. 191 - 203. 3. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80054914028&partnerID=MN8TOARS . 10.1007/s12012-011-9111-5 . Cardiovascular Toxicology
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Alves, M.G., Journal of Cellular Biochemistry. 3872 - 3881. 12. 112. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80055000219&partnerID=MN8TOARS . 10.1002/jcb.23320 . Journal of Cellular Biochemistry
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Endurance training reverts heart mitochondrial dysfunction, permeability transition and apoptotic signaling in long-term severe hyperglycemia
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Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells
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Long-term hyperglycaemia decreases gastrocnemius susceptibility to permeability transition
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Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function
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Mitochondrial involvement in cardiac apoptosis during ischemia and reperfusion: can we close the box?
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Parabens in male infertility-Is there a mitochondrial connection?
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Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?
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Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats
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Endurance training improves gastrocnemius mitochondrial function despite increased susceptibility to permeability transition
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Investigating drug-induced mitochondrial toxicity: A biosensor to increase drug safety?
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Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)-A model for endangered species
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Electrochemical oxidation of berberine and of its oxidation products at a glassy carbon electrode
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Sanguinarine cytotoxicity on mouse melanoma K1735-M2 cells-Nuclear vs. mitochondrial effects
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Inhibition of the adenine nucleotide translocator by N-acetyl perfluorooctane sulfonamides in vitro
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Quercetin, kaempferol and biapigenin from hypericum perforatum are neuroprotective against excitotoxic insults
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Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak
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Drug-induced mitochondrial dysfunction in cardiac and skeletal muscle injury.
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Complex formation between heptakis(2,6-di-O-methyl)-ß-cyclodextrin and cyclopentadienyl molybdenum(II) dicarbonyl complexes: Structural studies and cytotoxicity evaluations
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Beneficial effects of exercise on muscle mitochondrial function in diabetes mellitus
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Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage
Cardoso, S., Free Radical Biology and Medicine. 1395 - 1402. 10. 45. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54349099428&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2008.08.008 . Free Radical Biology and Medicine
Disruption of hepatic mitochondrial bioenergetics is not a primary mechanism for the toxicity of methoprene - relevance for toxicological assessment.
Monteiro JP; Oliveira PJ; Moreno AJ; Jurado AS, 2008. http://europepmc.org/abstract/med/18511104 . 10.1016/j.chemosphere.2008.04.024 .
Diabetes and the impairment of reproductive function: Possible role of mitochondria and reactive oxygen species
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Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line
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Mitochondria as targets for neuronal protection against excitotoxicity: A role for phenolic compounds?
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Oliveira, P.J., Journal of Biochemical and Molecular Toxicology. 6. 21. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36749085079&partnerID=MN8TOARS . 10:1002/jbt . Journal of Biochemical and Molecular Toxicology
Unaltered hepatic oxidative phosphorylation and mitochondrial permeability transition in Wistar rats treated with nimesulide: Relevance for nimesulide toxicity characterization
Moreno, A.J., Journal of Biochemical and Molecular Toxicology. 53 - 61. 2. 21. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247399590&partnerID=MN8TOARS . 10.1002/jbt.20159 . Journal of Biochemical and Molecular Toxicology
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: Comparison with direct effects on isolated mitochondrial fractions
Pereira, G.C., Journal of Pharmacology and Experimental Therapeutics. 636 - 649. 2. 323. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548974344&partnerID=MN8TOARS . 10.1124/jpet.107.128017 . Journal of Pharmacology and Experimental Therapeutics
Vitamin E prevents hypobaric hypoxia-induced mitochondrial dysfunction in skeletal muscle
Magalhães, J., Clinical Science. 459 - 466. 11-12. 113. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-36849067904&partnerID=MN8TOARS . 10.1042/CS20070075 . Clinical Science
Inhibition of mitochondrial bioenergetics by carbaryl is only evident for higher concentrations - Relevance for carbaryl toxicity mechanisms
Moreno, A.J.M., Chemosphere. 404 - 411. 3. 66. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751232011&partnerID=MN8TOARS . 10.1016/j.chemosphere.2006.06.030 . Chemosphere
Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide - Characterization of morphological features of cell death
Sardão, V.A., BMC Cell Biology. 8. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947598915&partnerID=MN8TOARS . 10.1186/1471-2121-8-11 . BMC Cell Biology
Doxorubicin-induced thiol-dependent alteration of cardiac mitochondrial permeability transition and respiration
Oliveira, P.J., Biochemistry (Moscow). 194 - 199. 2. 71. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645277082&partnerID=MN8TOARS . 10.1134/S000629790602012X . Biochemistry (Moscow)
Decreased ANT content in Zucker fatty rats: Relevance for altered hepatic mitochondrial bioenergetics in steatosis
Teodoro, J., FEBS Letters. 2153 - 2157. 8. 580. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645241135&partnerID=MN8TOARS . 10.1016/j.febslet.2006.02.078 . FEBS Letters
Pt(II) vs Pd(II) polyamine complexes as new anticancer drugs: A structure-activity study
Fiuza, S.M., Letters in Drug Design and Discovery. 149 - 151. 3. 3. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645876182&partnerID=MN8TOARS . 10.2174/157018006776286989 . Letters in Drug Design and Discovery
Esterification prevents induction of the mitochondrial permeability transition by N-acetyl perfluorooctane sulfonamides
O'Brien, T.M., Chemical Research in Toxicology. 1305 - 1312. 10. 19. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750209492&partnerID=MN8TOARS . 10.1021/tx060132r . Chemical Research in Toxicology
Endurance training limits the functional alterations of heart rat mitochondria submitted to in vitro anoxia-reoxygenation
Ascensão, A., International Journal of Cardiology. 169 - 178. 2. 109. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33646109584&partnerID=MN8TOARS . 10.1016/j.ijcard.2005.06.003 . International Journal of Cardiology
Effects of endurance training and acute doxorubicin treatment on rat heart mitochondrial alterations induced by in vitro anoxia-reoxygenation
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Depletion of adenine nucleotide translocator protein in heart mitochondria from doxorubicin-treated rats - Relevance for mitochondrial dysfunction
Oliveira, P.J., Toxicology. 160 - 168. 2-3. 220. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33244492919&partnerID=MN8TOARS . 10.1016/j.tox.2005.12.009 . Toxicology
Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis
Ascensão, A., American Journal of Physiology - Heart and Circulatory Physiology. 2 58-2. 289. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23744489541&partnerID=MN8TOARS . 10.1152/ajpheart.01249.2004 . American Journal of Physiology - Heart and Circulatory Physiology
Are the antioxidant properties of carvedilol important for the protection of cardiac mitochondria?
Oliveira, P.J., Current Vascular Pharmacology. 147 - 158. 2. 3. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18144430946&partnerID=MN8TOARS . 10.2174/1570161053586903 . Current Vascular Pharmacology
Bile acids are toxic for isolated cardiac mitochondria: a possible cause for hepatic-derived cardiomyopathies?
Ferreira M; Coxito PM; Sardão VA; Palmeira CM; Oliveira PJ; Ferreira, M., Cardiovascular toxicology. 63 - 73. 1. 5. 2005. http://europepmc.org/abstract/med/15738586 . 10.1385/ct:5:1:063 . Cardiovascular toxicology
Dietary vitamin E decreases doxorubicin-induced oxidative stress without preventing mitochondrial dysfunction
Berthiaume, J.M., Cardiovascular Toxicology. 257 - 267. 3. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144450968&partnerID=MN8TOARS . 10.1385/CT:5:3:257 . Cardiovascular Toxicology
Cardiac mitochondrial alterations observed in hyperglycaemic rats--what can we learn from cell biology?
Oliveira PJ; Oliveira, P.J., Current diabetes reviews. 11 - 21. 1. 1. 2005. http://europepmc.org/abstract/med/18220578 . 10.2174/1573399052952578 . Current diabetes reviews
Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.
Oliveira PJ; Rolo AP; Sardão VA; Monteiro P; Gonçalves L; Providência LA; Palmeira CM; Moreno AJ; Oliveira, P.J., Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 1291 - 1298. 10. 23. 2004. http://europepmc.org/abstract/med/15641294 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats
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Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity
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Carvedilol Inhibits the Mitochondrial Permeability Transition by an Antioxidant Mechanism
Oliveira, P.J., Cardiovascular Toxicology. 11 - 20. 1. 4. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1942486470&partnerID=MN8TOARS . 10.1385/CT:4:1:11 . Cardiovascular Toxicology
Calcium-dependent mitochondrial permeability transition is augmented in the kidney of Goto-Kakizaki diabetic rat
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Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC
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Chenodexycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: Protective role of carvedilol
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Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease? | Colestase crónica e funçá~o mitocondrial cardíaca em ratos wistar: Um modelo para alterações cardiovasculares no contexto de doenças hepáticas crónicas?
Oliveira, P.J., Revista Portuguesa de Cardiologia. 67 - 75. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia
Diabetes induces metabolic adaptations in rat liver mitochondria: Role of coenzyme Q and cardiolipin contents
Ferreira, F.M., Biochimica et Biophysica Acta - Molecular Basis of Disease. 113 - 120. 2. 1639. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0642345079&partnerID=MN8TOARS . 10.1016/j.bbadis.2003.08.001 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats
Oliveira, P.J., FEBS Letters. 511 - 514. 3. 554. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242541631&partnerID=MN8TOARS . 10.1016/S0014-5793(03)01233-X . FEBS Letters
Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with a-naphthyl-isothiocyanate (ANIT)
Palmeira, C.M., Toxicology. 185 - 196. 3. 190. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0042133192&partnerID=MN8TOARS . 10.1016/S0300-483X(03)00163-X . Toxicology
Reduction in cardiac mitochondrial calcium loading capacity is observable during a-naphthylisothiocyanate-induced acute cholestasis: A clue for hepatic-derived cardiomyopathies?
Oliveira, P.J., Biochimica et Biophysica Acta - Molecular Basis of Disease. 39 - 45. 1. 1637. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037454702&partnerID=MN8TOARS . 10.1016/S0925-4439(02)00212-0 . Biochimica et Biophysica Acta - Molecular Basis of Disease
Pharmacological modulation of mitochondrial function during ischemia and reperfusion | Modulação farmacológica da função mitocondrial no contexto da isquemia e reperfusão
Monteiro, P., Revista Portuguesa de Cardiologia. 407 - 429. 3. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038795126&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia
Mitochondria: Role in ischemia, reperfusion and cell death | Mitocôndrias: Que papel na isquémia, reperfusão e morte celular?
Monteiro, P., Revista Portuguesa de Cardiologia. 233 - 254. 2. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037732545&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia
Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.
Ferreira FM; Oliveira PJ; Rolo AP; Santos MS; Moreno AJ; da Cunha MF; Seiça R; Palmeira CM; Ferreira, F.M., Archives of Toxicology. 194 - 200. 4. 77. 2003. http://europepmc.org/abstract/med/12698234 . Archives of Toxicology
Mitochondria: role in ischemia, reperfusion and cell death.
Monteiro P; Oliveira PJ; Gonçalves L; Providência LA, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12769003 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.
Oliveira PJ; Esteves T; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12712810 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition | Carvedilol: Relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondrial
Oliveira, P.J., Revista Portuguesa de Cardiologia. 55 - 62. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia
Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?
Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2003. http://europepmc.org/abstract/med/12712811 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats
Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, Journal of Investigative Medicine. 86 - 94. 2. 51. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037338705&partnerID=MN8TOARS . Journal of Investigative Medicine
Caffeine enhances the calcium-dependent cardiac mitochondrial permeability transition: Relevance for caffeine toxicity
Sardão, V.A., Toxicology and Applied Pharmacology. 50 - 56. 1. 179. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037082662&partnerID=MN8TOARS . 10.1006/taap.2001.9334 . Toxicology and Applied Pharmacology
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion? | Impacto do carvedilol sobre o dano mitocondrial induzido por hipoxantina/xantina oxidase - Que papel na isquemia e reperfusão do miocárdio?
Oliveira, P.J., Revista Portuguesa de Cardiologia. 1447 - 1455. 12. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia
Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis
Rolo, A.P.; Rolo AP; Oliveira PJ; Seiça R; Santos MS; Moreno AJ; Palmeira CM, Journal of Investigative Medicine. 193 - 200. 3. 50. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS . Journal of Investigative Medicine
Study of carvedilol by combined Raman spectroscopy and ab initio MO calculations
Marques, M.P.M., Journal of Raman Spectroscopy. 778 - 783. 10. 33. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036773098&partnerID=MN8TOARS . 10.1002/jrs.916 . Journal of Raman Spectroscopy
Impact of diabetes on induction of the mitochondrial permeability transition.
Oliveira PJ; Rolo AP; Seiça R; Sardão V; Monteiro P; Gonçalves L; Providência L; et al, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 759 - 766. 6. 21. 2002. http://europepmc.org/abstract/med/12194377 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?
Oliveira PJ; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 2002. http://europepmc.org/abstract/med/12621918 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of a-naphthylisothiocyanate
Rolo, A.P., Toxicology and Applied Pharmacology. 20 - 26. 1. 182. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036070550&partnerID=MN8TOARS . 10.1006/taap.2002.9434 . Toxicology and Applied Pharmacology
Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore
Rolo, A.P., Biochemical Pharmacology. 1449 - 1454. 11. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00620-7 . Biochemical Pharmacology
Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate
Oliveira, P.J.; Oliveira PJ; Rolo AP; Seiça R; Palmeira CM; Santos MS; Moreno AJ, Bioscience Reports. 45 - 53. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034905572&partnerID=MN8TOARS . 10.1023/a:1010482017540 . Bioscience Reports
Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria
Rolo, A.P., Bioscience Reports. 73 - 80. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS . 10.1023/A:1010438202519 . Bioscience Reports
Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury
Oliveira, P.J., Cardiovascular Toxicology. 205 - 213. 3. 1. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS . 10.1385/CT:1:3:205 . Cardiovascular Toxicology
Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial KATP channels?
Oliveira, P.J., Life Sciences. 123 - 132. 2. 69. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS . 10.1016/S0024-3205(01)01109-2 . Life Sciences
Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore
Oliveira, P.J., European Journal of Pharmacology. 231 - 237. 3. 412. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS . 10.1016/S0014-2999(01)00745-2 . European Journal of Pharmacology
Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.
Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2000. http://europepmc.org/abstract/med/10966524 . 10.1093/toxsci/57.1.177 .
Carvedilol inhibits the exogenous NADH dehydrogenase in rat heart mitochondria
Oliveira, P.J., Archives of Biochemistry and Biophysics. 279 - 285. 2. 374. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034652094&partnerID=MN8TOARS . 10.1006/abbi.1999.1624 . Archives of Biochemistry and Biophysics
Effects of carvedilol on isolated heart mitochondria: Evidence for a protonophoretic mechanism
Oliveira, P.J., Biochemical and Biophysical Research Communications. 82 - 87. 1. 276. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034675219&partnerID=MN8TOARS . 10.1006/bbrc.2000.3374 . Biochemical and Biophysical Research Communications
5 305 out of 305 Publications
All projects
Information of exclusive responsibility of the researcher 13-10-2024 , from platform CIÊNCIAVITAE.
2023/03/01 - 2028/08/31
PAS GRAS - De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults
HORIZON-HLTH-2022-STAYHLTH- 101080329
Universidade de Coimbra
Funders: European Commission
2023/03/01 - 2027/02/28
EXCELScIOR
101087416
Researcher
Universidade de Coimbra
Funders: European Commission
2023/03/01 - 2024/08/31
Novas abordagens terapêuticas para a obesidade baseadas na sinalização dopaminérgica periférica
2022.05822.PTDC
Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2023/03/10 - 2024/09/09
Desferrização da ataxia de Friedreich com quelantes inovadores direcionados para a mitocôndria
2022.04633.PTDC
Universidade do Porto Faculdade de Ciências
Funders: Fundação para a Ciência e a Tecnologia
2022/01/15 - 2025/01/14
Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis
PTDC/BTM-ORG/0055/2021
Universidade de Coimbra; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2022/01/01 - 2023/06/30
Mitocôndria como potencial mediador do dimorfismo sexual nas alterações pato-morfológicas da microglia e ansiedade causadas pelo stress pré-natal<br>
EXPL/MED-NEU/1002/2021
Universidade de Coimbra; CNC.IBILI
Funders: Fundação para a Ciência e a Tecnologia
2022/01/01 - 2023/06/30
Função da homeostasia tiol-mitocondrial na neurodegeneração: implicações para a esclerose lateral amiotrófica
EXPL/BTM-TEC/1407/2021
Universidade de Coimbra; CNC.IBILI
Funders: Fundação para a Ciência e a Tecnologia
2022/06/01 - 2023/05/31
Proof of Concept “MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease
181226
Principal investigator
CIBB - Center for Innovative Biomedicine and Biotechnology
Funders: Agência para a Competitividade e Inovação IP
2021/01/01 - 2025/12/31
Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado
LA/P/0058/2020
Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2021
Summer with Science: Research, Development and Interdisciplinary Innovation in the Physiolopathology of Aging and Lifestyle-dependent Diseases
n.a.
Principal investigator
CIBB - Center for Innovative Biomedicine and Biotechnology
Funders: Fundação para a Ciência e a Tecnologia
2021/01/01 - 2023/12/31
Organelle-targeted Radiocomplexes for Auger Therapy of Cancer
PTDC/MED-QUI/1554/2020
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento; Centro de Ciências e Tecnologias Nucleares; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2020/07/01 - 2023/06/30
Preservação do património natural e cultural e validação científica das práticas com plantas medicinais do Vale do Côa
COA/BRB/0019/2019
Universidade de Coimbra; CNC.IBILI; Instituto Politécnico de Bragança; Universidade de Aveiro
Funders: Fundação para a Ciência e a Tecnologia
2020 - 2020
Summer Course: Methodologies for Scientific Research – Interdisciplinary Research, Development and Innovation in Cell and Molecular Metabolism
15-20/7/245
Principal investigator
CIBB - Center for Innovative Biomedicine and Biotechnology
Funders: Fundação para a Ciência e a Tecnologia
2019/01/01 - 2024/12/31
Lifelong exercise: modulating immunometabolic pathways for decreasing cancer risk.
10/22
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular; Universidade de Coimbra Centro de Investigação do Desporto e da Actividade Física; Unidade Local de Saúde de Coimbra EPE
Funders: Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia
2019/01/01 - 2019/12/31
CNC. IBILI
UID/NEU/04539/2019
Universidade de Coimbra; Universidade Nova de Lisboa ¿Laboratório de Instrumentação Engenharia Biomédica e Física da Radiação; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2021
The Role of Visceral Fructose Metabolism in the Development of Non-alcoholic Fatty Liver Disease
02/SAICT/2017/028147
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2021
MitoCIN- Hydroxycinnamic derivatives, methods and uses thereof, Intelectual Protection Support
Portugal2020/call 17/SI/2015/37586
Principal investigator
2018 - 2021
Development of mitochondriotropic antioxidants based on a hydroxybenzoic acid scaffold, Intelectual Protection Support
Portugal2020/call 04/SAICT/2017/037892
Principal investigator
2018 - 2021
VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproducts
POCI-01-0145-FEDER-029152
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Trás-os-Montes e Alto Douro
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2021
Mito4ALS: Development of Novel Mitochondria-Targeted Antioxidants for Improving SOD1-Familial Amyotrophic Lateral Sclerosis Phenotype
PTDC/MED-FAR/29391/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018/06/01 - 2022/01/31
O papel do metabolismo extra-hepático da frutose no desenvolvimento de doença hepática gordurosa não alcoólica
PTDC/BIA-BQM/28147/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Aveiro; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018/06/01 - 2022/02/28
Eficácia pré-clínica do sulforafano ou do extrato total de Brássicas: uma estratégia para combater a obesidade e valorizar os subprodutos de Brássicas
PTDC/ASP-HOR/29152/2017
Universidade de Trás-os-Montes e Alto Douro; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018/07/26 - 2021/07/25
Uso de fitoquímicos redox-activos para desencadear a hormesis mitocondrial: Desenvolvimento de uma nova geração de ingredientes para a cosmética
PTDC/BIA-MOL/28607/2017
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2021
MitoSHIELD - Redox-active Phytochemicals Triggering Mitochondrial Hormesis: Developing a New Generation of Cosmetic Active Ingredients
PTDC/BTM-SAL/29297/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2021
Development and validation of innovative screening methods for mitochondrial health modulators
PTDC/BTM-SAL/29297/2017
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2018
Mitochondrial-derived Peptides in Cell Homeostasis
FLAD Healthcare 2020
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação Luso-Americana
2017 - 2019
Tackling CANcer STEM CELls: A Challenge and an Opportunity to Advance in Anti-cancer Therapy
SAICTPAC/0022/2015
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2017/01 - 2019/12
FOIE GRAS - Bioenergetic Remodeling in the Pathophysiology and Treatment of Non-Alcoholic Fatty Liver Disease
722619
Principal investigator
Funders: European Commission
2017/07 - 2020/06
mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease
734719
Principal investigator
Funders: European Commission
2016/04/01 - 2019/09/30
EXERCITANDO O FUTURO: Exercício Voluntário Durante Diabetes Gestacional com uma Estratégia para Melhorar a Função Mitocondrial na Descendência
PTDC/DTP-DES/1082/2014
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Faculdade de Desporto
Funders: Fundação para a Ciência e a Tecnologia
2016/04/01 - 2019/09/30
MitoBOOST: Uma Terapeutica de Nova Geração para a Doença de Fígado Gordo Não Alcoólico Baseado na Entrega Inteligente de Antioxidantes à Mitocôndria
PTDC/DTP-FTO/2433/2014
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Faculdade de Ciências
Funders: Fundação para a Ciência e a Tecnologia
2016 - 2019
Exercising obesity - The Role of Exercise Against Endoplasmic Reticulum Stress in Obesity-induced Liver Disease
PTDC/DTP-DES/7087/2014
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2015 - 2018
FishFree: A Contribution to the Validation of an Alternative Assay for Fish Lethal Ttesting
PTDC/AAG-TEC/4966/2014
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2015/10 - 2018/09
EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring
grant.Provided by PTCRIS: 139707
Researcher
CNC.IBILI
Funders: Fundação para a Ciência e a Tecnologia
2015/10 - 2018/09
MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria
grant.Provided by PTCRIS: 141059
Principal investigator
Funders: Fundação para a Ciência e a Tecnologia
2014 - 2015
Hypercholesterolemia as a risk factor for Alzheimer’s Disease: impact on nitric oxide bioavailability and bioactivity
8. Transnational Cooperation Agreement Project, CAPES/FCT 2013
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2013 - 2015
Pathophysiology of Persistent Doxorubicin Cardiotoxicity: a Mitochondrial-Epigenetics Link
PTDC/DTP-FTO/1180/2012
Principal investigator
Funders: Foundation for Science and Technology - Portugal
2011/01/01 - 2012/12/31
Strategic Project - LA 1 - 2011-2012
PEst-C/SAU/LA0001/2011
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2011 - 2014
Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction
PTDC/SAU-TOX/110952/2009
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Foundation for Science and Technology - Portugal
2011/03/01 - 2014/08/31
Actividade Protectora da SIRT3 na Disfunção Mitocondrial Induzida por Fármacos
PTDC/SAU-TOX/110952/2009
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2010/04 - 2013/03
Opening Pandora's Box for Active Anti-Breast Cancer Therapy - The Role of Selective Targeting to Mitochondria
101409
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia, I.P.
2010 - 2013
Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics
PTDC/QUI-BIQ/101052/2008
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Foundation for Science and Technology - Portugal
2010 - 2013
Metabolism as a Modulator of Stem Cell Pluripotency and Differentiation
PTDC/EBB-EBI/101114/2008
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Foundation for Science and Technology - Lisbon
2010 - 2013
Can Phytoestrogens be Safe and Effective Food Additives for Women During Menopause? - An In Vitro and In Vivo Approach to the problem
PTDC/AGR-ALI/108326/2008
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Foundation for Science and Technology - Portugal
2010/05/01 - 2013/10/30
Clarificação do Papel Mitocondrial na Cardiotoxicidade da Doxorubicina Usando um Sistema de Perfusão de Corações Intactos - Papel de Diferentes Calendários de Tratamento com Doxorubicina
PTDC/SAU-OSM/104731/2008
Researcher
Instituto do Mar; University of Minnesota Twin Cities School of Medicine Duluth Campus; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia; Fundação para a Ciência e a Tecnologia
2010 - 2013
Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System – Impact of Different Doxorubicin Treatment Regimens
PTDC/SAU-OSM/104731/2008
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2010 - 2012
MitocancerStem ¿ Role of Mitochondrial Physiology in Tumor Cell Resistance to Chemotherapeutics
FP7-People-2009-IEF 251850
Funders: European Commission
2010/04/01 - 2013/03/31
A Abertura da Caixa de Pandora Para uma Terapia Activa Anti-cancro da Mama - O Papel do Direccionamento Selectivo da Mitocôndria
PTDC/QUI-QUI/101409/2008
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Mercer University School of Medicine; University of Minnesota Medical School - Duluth Campus; Universidade de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2010 - 2013
Role of Mitochondrial Physiology in Tumor Stem Cell Resistance to Chemotherapeutics
PTDC/QUI-BIQ/101052/2008
Funders: Foundation for Science and Technology - Portugal
2009 - 2011
Anticancer Activity of Novel Polyamine Pd(II) Complexes - A Multidisciplinary Study
PTDC/QUI/66701/2006
Researcher
Funders: Foundation for Science and Technology - Portugal
2007 - 2009
Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells - Signalling Pathways Involved
PTDC/QUI/64358/2006
Researcher
Funders: Foundation for Science and Technology - Portugal
2007/09/15 - 2010/03/13
Novel Mitochondrial Mechanisms for the Cardioselective Toxicity of Doxorubicin
PTDC/SAU-OSM/64084/2006
Universidade do Porto Centro de Investigação em Actividade Física Saúde e Lazer; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2005 - 2008
Development of Novel Anticancer Agents: Phenolic Derivatives of Natural and Synthetic Origin - Structure-Activity Relationships
POCTI/QUI/55631/2004
Researcher
Funders: Foundation for Science and Technology - Portugal
2005/07/01 - 2008/09/30
Influência das Soluções de Preservação para Transplante nos Perfis Metabólico e Imunológico Cardíacos
POCI/SAU-OBS/55802/2004
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2005/10/15 - 2007/04/15
Desenvolvimento de Novos Agentes Anticancerígenos: Derivados Fenólicos de Origem Natural ou Sintética - Relações Estrutura-Actividade
POCI/QUI/55631/2004
Universidade de Coimbra; Universidade de Coimbra Unidade de Investigação e Desenvolvimento Química-Física Molecular; Universidade do Porto Faculdade de Farmácia; Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto; Universidade do Porto Faculdade de Ciências
Funders: Fundação para a Ciência e a Tecnologia
2003/02/15 - 2006/10/14
ADRIAMYCIN - ASSOCIATED CARDIOMYOPATHIES - IMPACT OF METABOLIC THRESHOLDS IN SELECTIVE ORGAN TOXICITY AND DIFFERENTIAL ACTIVATION OF MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS
SFRH/BPD/8359/2002
Funders: Fundação para a Ciência e a Tecnologia
2000 - 2003
Mitochondria and diabetes: mitochondrial function in the brain and heart of non-insulin dependent animal models (Goto-Kakizaki)
POCTI/ESP/43642/1999
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia; Fundação para a Ciência e a Tecnologia
2000 - 2003
Mitochondria and diabetes: mitochondrial function in the brain and heart of non-insulin dependent animal models (Goto-Kakizaki)
POCTI/ESP/43642/1999
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2000/01/01 - 2003/01/31
UTILIZAÇÃO SISTEMÁTICA DE CARDIOMIÓCITOS E DE MITOCÔNDRIAS CARDÍACAS ISOLADAS COMO MODELO DE AVALIAÇÃO FARMACOLÓGICA E TOXICOLÓGICA DE FÁRMACOS COM ACÇÃO A NÍVEL CARDÍACO
PRAXIS XXI/BD/21494/99
Funders: Fundação para a Ciência e a Tecnologia
5 59 out of 59 projects
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