Publications

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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria

Amorim, Ricardo; Magalhães, Carina C.; Borges, Fernanda; Oliveira, Paulo J.; Teixeira, José, Biology. 4. 12. 2023. http://dx.doi.org/10.3390/biology12040595 . 10.3390/biology12040595 . Biology

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease.

Marta Afonso; Islam T; Magusto J; Amorim R; Lenoir V; F Simões R; Teixeira J; et al, Hepatology (Baltimore, Md.). 2022. https://doi.org/10.1002/hep.32756 . 10.1002/hep.32756 . Hepatology (Baltimore, Md.)

Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems

Ricardo Amorim; Inês C.M. Simões; José Teixeira; Fernando Cagide; Yaiza Potes; Pedro Soares; Adriana Carvalho; et al, Redox Biology. 102400 - 102400. 55. 2022. http://dx.doi.org/10.1016/j.redox.2022.102400 . 10.1016/j.redox.2022.102400 . Redox Biology

Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage

Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al, Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine

Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells

Amorim, Ricardo; Simões, Inês C. M.; Veloso, Caroline; Carvalho, Adriana; Simões, Rui F.; Pereira, Francisco B.; Thiel, Theresa; et al, Nutrients. 5. 13. 2021. http://dx.doi.org/10.3390/nu13051723 . 10.3390/nu13051723 . Nutrients

The Alterations of Mitochondrial Function during NAFLD Progression An Independent Effect of Mitochondrial ROS Production

Simões, Inês C. M.; Amorim, Ricardo; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana; Pereira, Susana P.; Simões, Rui F.; et al, International Journal of Molecular Sciences. 13. 22. 2021. http://dx.doi.org/10.3390/ijms22136848 . 10.3390/ijms22136848 . International Journal of Molecular Sciences

Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts

Teixeira, José; Basit, Farhan; Willems, Peter H.G.M.; Wagenaars, Jori A.; van de Westerlo, Els; Amorim, Ricardo; Cagide, Fernando; et al, Free Radical Biology and Medicine. 314 - 324. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.023 . 10.1016/j.freeradbiomed.2020.12.023 . Free Radical Biology and Medicine

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents

Catarina Oliveira; Donatella Bagetta; Fernando Cagide; José Teixeira; Ricardo Amorim; Tiago Silva; Jorge Garrido; et al, European Journal of Medicinal Chemistry. 116 - 129. 174. 2019. https://doi.org/10.1016/j.ejmech.2019.04.026 . 10.1016/j.ejmech.2019.04.026 . European Journal of Medicinal Chemistry

Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction

Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al, European Journal of Medicinal Chemistry. 525 - 545. 167. 2019. http://dx.doi.org/10.1016/j.ejmech.2019.01.055 . 10.1016/j.ejmech.2019.01.055 . European Journal of Medicinal Chemistry

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative

Teixeira, José; Amorim, Ricardo; Santos, Katia; Soares, Pedro; Datta, Sandipan; Cortopassi, Gino A.; Serafim, Teresa L.; et al, Toxicology. 123 - 139. 393. 2018. http://dx.doi.org/10.1016/j.tox.2017.11.014 . 10.1016/j.tox.2017.11.014 . Toxicology

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira, Journal of Enzyme Inhibition and Medicinal Chemistry. 567 - 576. 1. 33. 2018. https://doi.org/10.1080%2F14756366.2018.1442831 . 10.1080/14756366.2018.1442831 . Journal of Enzyme Inhibition and Medicinal Chemistry

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors

Catarina Oliveira; Fernando Cagide; José Teixeira; Ricardo Amorim; Lisa Sequeira; Francesco Mesiti; Tiago Silva; et al, Frontiers in Chemistry. 6. 2018. https://doi.org/10.3389%2Ffchem.2018.00126 . 10.3389/fchem.2018.00126 . Frontiers in Chemistry

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy

Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges, Bioconjugate Chemistry. 2723 - 2733. 8. 29. 2018. https://doi.org/10.1021%2Facs.bioconjchem.8b00383 . 10.1021/acs.bioconjchem.8b00383 . Bioconjugate Chemistry

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria

Teixeira, José; Oliveira, Catarina; Amorim, Ricardo; Cagide, Fernando; Garrido, Jorge; Ribeiro, José A.; Pereira, Carlos M.; et al, Scientific Reports. 1. 7. 2017. http://dx.doi.org/10.1038/s41598-017-07272-y . 10.1038/s41598-017-07272-y . Scientific Reports

Decreasing the toxicity of paraquat through the complexation with sodium salicylate: Stoichiometric analysis

Gales, Luís; Amorim, Ricardo; Afonso, Carlos Manuel M.; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge, Toxicology. 96 - 98. 336. 2015. http://dx.doi.org/10.1016/j.tox.2015.08.005 . 10.1016/j.tox.2015.08.005 . Toxicology

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2023 -

Remodelação metabólica e mitocondrial induzida pela atividade física em fibroblastos de pacientes com a Doença de Parkinson

2022.01232.PTDC

Other

Funders: Associação para a Inovação e Desenvolvimento da FCT

2022/06 -

MitoBOOST v2.0 - A Proof of Concept for the Use of Mitochondria-Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease

V2.0 IT137-22-151

Post-doc

Funders: Comissão de Coordenação e Desenvolvimento Regional do Centro (CCDRC)

2021 -

Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis

PTDC/BTM-ORG/0055/2021

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Associação para a Inovação e Desenvolvimento da FCT

2021/01/01 -

BraveHEART: Improving Nature by Addressing Bioactiv Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications in Non-Alcoholic Fatty Liver Disease

EXPL/BIA-BQM/1361/2021

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Associação para a Inovação e Desenvolvimento da FCT

2019/01/01 - 2019/12/31

CNC. IBILI

UID/NEU/04539/2019

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2019/06/01 -

CôaMedPlants: Preservation of natural and cultural heritage and scientific validation of practices with medicinal plants from Côa Valley

COA/BRB/0019/2019

Post-doc Fellow

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Associação para a Inovação e Desenvolvimento da FCT

2018/07/26 - 2021/07/25

Uso de fitoquímicos redox-activos para desencadear a hormesis mitocondrial: Desenvolvimento de uma nova geração de ingredientes para a cosmética

PTDC/BIA-MOL/28607/2017

Universidade do Porto; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018/07/26 - 2021

SkinSHIELD - Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active ingredients

POCI-01-0145-FEDER-028607

PhD Student Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Associação para a Inovação e Desenvolvimento da FCT

2017/01/01 - 2017/10/31

MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria Pathophysiology

PTDC/DTP-FTO/2433/2014

Research Fellow

Funders: Associação para a Inovação e Desenvolvimento da FCT

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