Ricardo Fernando Santos Amorim

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PhD Student

Publications

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Information about journal articles, updated at 26-06-2022, from platform CIÊNCIAVITAE.

Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage

Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al, Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine

Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells

Amorim, Ricardo; Simões, Inês C. M.; Veloso, Caroline; Carvalho, Adriana; Simões, Rui F.; Pereira, Francisco B.; Thiel, Theresa; et al, Nutrients. 5. 13. 2021. http://dx.doi.org/10.3390/nu13051723 . 10.3390/nu13051723 . Nutrients

The Alterations of Mitochondrial Function during NAFLD Progression An Independent Effect of Mitochondrial ROS Production

Simões, Inês C. M.; Amorim, Ricardo; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana; Pereira, Susana P.; Simões, Rui F.; et al, International Journal of Molecular Sciences. 13. 22. 2021. http://dx.doi.org/10.3390/ijms22136848 . 10.3390/ijms22136848 . International Journal of Molecular Sciences

Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts

Teixeira, José; Basit, Farhan; Willems, Peter H.G.M.; Wagenaars, Jori A.; van de Westerlo, Els; Amorim, Ricardo; Cagide, Fernando; et al, Free Radical Biology and Medicine. 314 - 324. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.023 . 10.1016/j.freeradbiomed.2020.12.023 . Free Radical Biology and Medicine

Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents

Catarina Oliveira; Donatella Bagetta; Fernando Cagide; José Teixeira; Ricardo Amorim; Tiago Silva; Jorge Garrido; et al, European Journal of Medicinal Chemistry. 116 - 129. 174. 2019. https://doi.org/10.1016/j.ejmech.2019.04.026 . 10.1016/j.ejmech.2019.04.026 . European Journal of Medicinal Chemistry

Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction

Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al, European Journal of Medicinal Chemistry. 525 - 545. 167. 2019. http://dx.doi.org/10.1016/j.ejmech.2019.01.055 . 10.1016/j.ejmech.2019.01.055 . European Journal of Medicinal Chemistry

Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative

Amorim, Ricardo, 2018. 10.1016/j.tox.2017.11.014 .

Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira, Journal of Enzyme Inhibition and Medicinal Chemistry. 567 - 576. 1. 33. 2018. https://doi.org/10.1080%2F14756366.2018.1442831 . 10.1080/14756366.2018.1442831 . Journal of Enzyme Inhibition and Medicinal Chemistry

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors

Catarina Oliveira; Fernando Cagide; José Teixeira; Ricardo Amorim; Lisa Sequeira; Francesco Mesiti; Tiago Silva; et al, Frontiers in Chemistry. 6. 2018. https://doi.org/10.3389%2Ffchem.2018.00126 . 10.3389/fchem.2018.00126 . Frontiers in Chemistry

Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy

Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges, Bioconjugate Chemistry. 2723 - 2733. 8. 29. 2018. https://doi.org/10.1021%2Facs.bioconjchem.8b00383 . 10.1021/acs.bioconjchem.8b00383 . Bioconjugate Chemistry

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria

Amorim, Ricardo, Scientific Reports. 2017. 10.1038/s41598-017-07272-y . Scientific Reports

Decreasing the toxicity of paraquat through the complexation with sodium salicylate

Amorim, Ricardo, Toxicology. 2015. 10.1016/j.tox.2015.08.005 . Toxicology

All projects

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Information of exclusive responsibility of the researcher 26-06-2022 , from platform CIÊNCIAVITAE.

2022/01/01 -

BraveHEART: Improving Nature by Addressing Bioactiv Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications in Non-Alcoholic Fatty Liver Disease

EXPL/BIA-BQM/1361/2021

PhD Student Fellow

2018/07/26 -

SkinSHIELD - Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active ingredients

SkinSHIELD - Redox-active phytochemicals triggering mitochondrial hormesis: developing a new generation of cosmetic active ingredients

PhD Student Fellow

2018/03/23 -

MitoBOOST: A Next-Generation Therapeutics for Non-Alcoholic Fatty Liver Disease Based on Smart Antioxidant Delivery to Mitochondria Pathophysiology

PTDC/DTP-FTO/2433/2014

PhD Student Fellow

Funders: Associação para a Inovação e Desenvolvimento da FCT

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