High-throughput/high-content screening platform

The high-throughput/high-content screening platform is equipped with state-of-the-art instrumentation to perform genome-wide loss- and gain-
of-function screenings using siRNA/miRNA/CRISPR libraries, as well as screenings using large-scale libraries of chemical compounds. This fully automated platform was specifically designed to promote flexibility and can thus accommodate cell-based screenings using diversified cell models that address a wide range of biological questions. The screening platform is rendered available to researchers within the CiBB ecosystem as well as to extra-mural investigators, fostering scientific collaborations.
The screening platform is integrated into the PT - OPENSCREEN consortium, part of Portuguese Roadmap of Research Infrastructures, as well as the European Research Infrastructure Consortium EU - OPENSCREEEN., and the AccelBio Collaborative Laboratory. In 2022, the platform was recognized as as a Partner Site (Specialised Screening site) of the European Research Infrastructure Consortium EU - OPENSCREEEN.