Innovative Therapies

Medical Microbiology

Medical Microbiology

Infection

Pathogenesis

Antimicrobial Resistance

Fungal Pathogens

Overview

The group main interests are centered in microbial agents of human disease, the biological traits relevant to infection, the mechanisms of resistance to antimicrobials, while seeking for innovative therapies and for preventive measures. We are particularly centered in studying fungal agents, although not excluding other agents of human infection. Besides Candida albicans, an important agent of opportunistic infection, we focus our studies in filamentous fungi, Alternaria spp., as agents involved in respiratory allergies. Our focuses are: 

1. Impact of the purinergic system in infection/colonization. We pursue how the purinergic metabolism and the adenosine A2A receptors can be modulated to ameliorate pathological conditions of the elderly such as chronic inflammation of the gut. Together with our internal and external collaborators we are also tackling the involvement of the purinergic system in the control of microbiota (including mycobiota) and infection.

2. Improving asthma diagnosis and immunotherapies In the last decades a growing number of serious opportunistic infections by environmental fungi is being registered, together with an increase of people suffering from serious respiratory allergies. We study the biological traits of molds, in particular Alternaria spp., relevant for its ability to colonize/infect the human host. By unraveling Alternaria alternata proteome we seek for novel tools to improve asthma diagnosis and immunotherapies. We also focus on the production of melanin (s) as a pathogenic and in the resistance to antifungals. We first identify the production of extracellular vesicles (EVs) by these filamentous fungi and that these EVs cargo are determinant on the pathogenesis of Alternaria.

3. Preventing infection: novel technologies to prevent airborne diseases; natural resources and synthetic molecules as antimicrobials/antibiofilm The resistance to antimicrobials, as one of the WHO priorities and the 2030 Agenda. We seek for novel strategies to fight against human infectious agents.The scientific interest in the control of pandemics took us to initiate a project with the aim of quantifying the SARS-CoV2 in indoors environments, especially in health care facilities. Lately, together with external collaborators specialists in air treatment (UC based) we implemented a facility to test air purification systems, using models of SARS-CoV-2.

Featured Articles

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Information about journal articles, updated at 29-12-2024, from platform CIÊNCIAVITAE.

Early Interaction of Alternaria infectoria Conidia with Macrophages

Almeida, M. C.; Antunes, D.; Silva, B. M. A.; Rodrigues, L.; Mota, M.; Borges, O.; Fernandes, C.; Gonçalves, T., 2019. Mycopathologia. 383 - 392. 3. 184. 2019. http://dx.doi.org/10.1007/s11046-019-00339-6 . 10.1007/s11046-019-00339-6 . published Mycopathologia

Candida Extracellular Nucleotide Metabolism Promotes Neutrophils Extracellular Traps Escape

Afonso, Mariana; Mestre, Ana Rita; Silva, Guilherme; Almeida, Ana Catarina; Cunha, Rodrigo A.; Meyer-Fernandes, José Roberto; Gonçalves, Teresa; Rodrigues, Lisa, 2021. Frontiers in Cellular and Infection Microbiology. 11. 2021. http://dx.doi.org/10.3389/fcimb.2021.678568 . 10.3389/fcimb.2021.678568 . published Frontiers in Cellular and Infection Microbiology

Characterization of Alternaria infectoria extracellular vesicles

Silva, B. M. A.; Prados-Rosales, R.; Espadas-Moreno, J.; Wolf, J. M.; Luque-Garcia, J. L.; Goncalves, T.; Casadevall, A., 2013. Medical Mycology. 202 - 210. 2. 52. 2013. http://dx.doi.org/10.1093/mmy/myt003 . 10.1093/mmy/myt003 . Medical Mycology

SARS-CoV-2 air and surface contamination in residential settings

Correia, Gil; Rodrigues, Luís; Afonso, Mariana; Mota, Marta; Oliveira, Joana; Soares, Rui; Tomás, Ana Luísa; et al, 2022. Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-22679-y . 10.1038/s41598-022-22679-y . Scientific Reports

Phagolysosomal remodeling to confine Candida albicans in the macrophage

Domingues, Neuza; Gonçalves, Teresa; Girao, Henrique, 2022. Trends in Microbiology. 519 - 523. 6. 30. 2022. http://dx.doi.org/10.1016/j.tim.2022.03.004 . 10.1016/j.tim.2022.03.004 . published Trends in Microbiology


Publications

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Information about journal articles, updated at 29-12-2024, from platform CIÊNCIAVITAE.

Distinct proteomes and allergen profiles appear across the life-cycle stages of Alternaria alternata

Strader, Michael Brad; Saha, Aishwarya L.; Fernandes, Chantal; Sharma, Kavita; Hadiwinarta, Christian; Calheiros, Daniela; Conde-de-Oliveira, Gonçalo; Gonçalves, Teresa; Slater, Jay E., 2024. Journal of Allergy and Clinical Immunology. 424 - 434. 2. 154. 2024. http://dx.doi.org/10.1016/j.jaci.2024.03.026 . 10.1016/j.jaci.2024.03.026 . published Journal of Allergy and Clinical Immunology

Caffeine Protects Keratinocytes from Trichophyton mentagrophytes Infection and Behaves as an Antidermatophytic Agent

Diogo M. da Fonseca; Lisa Rodrigues; José Sousa-Baptista; Félix Marcos-Tejedor; Marta Mota; Rodrigo A. Cunha; Chantal Fernandes; Teresa Gonçalves, 2024. International Journal of Molecular Sciences. 2024. https://doi.org/10.3390/ijms25158303 . 10.3390/ijms25158303 . International Journal of Molecular Sciences

Genetic Polymorphisms of P2RX7 but Not of ADORA2A Are Associated with the Severity of SARS-CoV-2 Infection

Jorge Lindo; Célia Nogueira; Rui Soares; Nuno Cunha; Maria Rosário Almeida; Lisa Rodrigues; Patrícia Coelho; et al, 2024. International Journal of Molecular Sciences. 2024. https://doi.org/10.3390/ijms25116135 . 10.3390/ijms25116135 . International Journal of Molecular Sciences

Health Status and COVID-19 Epidemiology in an Inland Region of Portugal: A Retrospective Study

Jorge Lindo; Patrícia Coelho; Catarina Gavinhos; Manuel Martins; Joana Liberal; António Jorge Ferreira; Teresa Gonçalves; Francisco Rodrigues, 2024. International Journal of Environmental Research and Public Health. 2024. https://doi.org/10.3390/ijerph21081033 . 10.3390/ijerph21081033 . International Journal of Environmental Research and Public Health

Cell wall nanoparticles from hyphae of Alternaria infectoria grown with caspofungin, nikkomycin, or pyroquilon trigger different activation profiles in macrophages

Daniela Antunes; Rita Domingues; Mariana Cruz-Almeida; Lisa Rodrigues; Olga Borges; Agostinho Carvalho; Arturo Casadevall; et al, 2024. Microbiology Spectrum. 2024. https://doi.org/10.1128/spectrum.00645-24 . 10.1128/spectrum.00645-24 . Microbiology Spectrum

Seaweed Calliblepharis jubata and Fucus vesiculosus Pigments: Anti-Dermatophytic Activity

Louisa Gomes; João Cotas; Fernandes, Chantal; Gonçalves, Teresa; Leonel Pereira, 2024. Applied Sciences. 4. 14. 2024. https://doi.org/10.3390/app14041456 . published Applied Sciences

Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection

Beatriz Cristovao; Lisa Rodrigues; Steve Catarino; Monica Abreu; Teresa Gonçalves; Neuza Domingues; Girao H, 2023. Microbiology Spectrum. 5. 11. 2023. http://dx.doi.org/10.1128/spectrum.01238-23 . 10.1128/spectrum.01238-23 . Microbiology Spectrum

Study of Ecological Relationship of Yeast Species with Candida albicans in the Context of Vulvovaginal Infections

Cátia Filipa Caetano; Carlos Gaspar; Ana Sofia Oliveira; Rita Palmeira-de-Oliveira; Lisa Rodrigues; Teresa Gonçalves; José Martinez-de-Oliveira; Ana Palmeira-de-Oliveira; Joana Rolo, 2023. Microorganisms. 2023. https://doi.org/10.3390/microorganisms11102398 . 10.3390/microorganisms11102398 . Microorganisms

The Chemical Profile, and Antidermatophytic, Anti-Inflammatory, Antioxidant and Antitumor Activities of Withania chevalieri A.E. Gonç. Ethanolic Extract

Edmilson Emanuel Monteiro Correia; Artur Figueirinha; Lisa Rodrigues; José Pinela; Ricardo C. Calhelha; Lillian Barros; Chantal Fernandes; Lígia Salgueiro; Teresa Gonçalves, 2023. Plants. 13. 12. 2023. https://doi.org/10.3390/plants12132502 . 10.3390/plants12132502 . published Plants

Antifungal Activity of Spent Coffee Ground Extracts

Daniela Calheiros; Maria Inês Dias; Ricardo C. Calhelha; Lillian Barros; Isabel C. F. R. Ferreira; Chantal Fernandes; Teresa Gonçalves, 2023. Microorganisms. 2. 11. 2023. https://doi.org/10.3390/microorganisms11020242 . 10.3390/microorganisms11020242 . published Microorganisms

Azorean Black Tea (Camellia sinensis) Antidermatophytic and Fungicidal Properties

Fernandes, Chantal; Sousa-Baptista, José; Lenha-Silva, Ana Filipa; Calheiros, Daniela; Correia, Edmilson; Figueirinha, Artur; Salgueiro, Lígia; Gonçalves, Teresa, 2023. Molecules. 23. 28. 2023. http://dx.doi.org/10.3390/molecules28237775 . 10.3390/molecules28237775 . Molecules

Mechanisms of Alternaria pathogenesis in animals and plants

Chantal Fernandes; Arturo Casadevall; Teresa Gonçalves, 2023. FEMS Microbiology Reviews. 6. 47. 2023. https://doi.org/10.1093/femsre/fuad061 . 10.1093/femsre/fuad061 . published FEMS Microbiology Reviews

SARS-CoV-2 air and surface contamination in residential settings

Correia, Gil; Rodrigues, Luís; Afonso, Mariana; Mota, Marta; Oliveira, Joana; Soares, Rui; Tomás, Ana Luísa; et al, 2022. Scientific Reports. 1. 12. 2022. http://dx.doi.org/10.1038/s41598-022-22679-y . 10.1038/s41598-022-22679-y . Scientific Reports

Seaweeds’ pigments and phenolic compounds with antimicrobial potential

Gomes, Louisa; Monteiro, Pedro; Cotas, João; Gonçalves, Ana M. M.; Fernandes, Chantal; Gonçalves, Teresa; Pereira, Leonel, 2022. Biomolecular Concepts. 89 - 102. 1. 13. 2022. http://dx.doi.org/10.1515/bmc-2022-0003 . 10.1515/bmc-2022-0003 . Biomolecular Concepts

Phagolysosomal remodeling to confine Candida albicans in the macrophage

Domingues, Neuza; Gonçalves, Teresa; Girao, Henrique, 2022. Trends in Microbiology. 519 - 523. 6. 30. 2022. http://dx.doi.org/10.1016/j.tim.2022.03.004 . 10.1016/j.tim.2022.03.004 . published Trends in Microbiology

Delayed Cutaneous Adverse Reaction of the AstraZeneca COVID-19 Vaccine in a Breastfed Female Infant: A Coincidence or a Rare Effect?

Patricia Diogo; Gil Correia; João Brochado Martins; Rui Soares; João Miguel Marques dos Santos; Teresa Gonçalves, 2022. Vaccines. 4. 10. 2022. https://www.mdpi.com/2076-393X/10/4/602 . 10.3390/vaccines10040602 . published Vaccines

Vulvovaginal Candida albicans Clinical Isolates¿ Resistance to Phagocytosis In-Vitro

Faria-Gonçalves, Paula; Oliveira, Ana Sofia; Gaspar, Carlos; Rodrigues, Lisa; Palmeira-de-Oliveira, Rita; Martinez-de-Oliveira, José; Gonçalves, Teresa; Palmeira-de-Oliveira, Ana; Rolo, Joana, 2022. Life. 6. 12. 2022. http://dx.doi.org/10.3390/life12060838 . 10.3390/life12060838 . published Life

Clustering of adenosine A 2B receptors with ectonucleotidases in caveolin-rich lipid rafts underlies immunomodulation by Leishmania amazonensis

Figueiredo, Amanda Braga; Oliveira e Castro, Renata Alves; Nogueira-Paiva, Nívia Carolina; Moreira, Filipa; Gonçalves, Francisco Queiroz; Soares, Rodrigo Pedro; Castro-Borges, William; et al, 2021. The FASEB Journal. 5. 35. 2021. http://dx.doi.org/10.1096/fj.202002396rr . 10.1096/fj.202002396rr . published The FASEB Journal

Electrospun composite fibers of PLA/PLGA blends and mesoporous silica nanoparticles for the controlled release of gentamicin sulfate

Batista, Henrique; Freitas, João P.; Abrunheiro, Alexandra; Gonçalves, Teresa; Gil, Maria H.; Figueiredo, Margarida; Coimbra, Patrícia, 2021. International Journal of Polymeric Materials and Polymeric Biomaterials. 71. 2021. http://dx.doi.org/10.1080/00914037.2021.1876053 . 10.1080/00914037.2021.1876053 . published International Journal of Polymeric Materials and Polymeric Biomaterials

Identification of Fungi Involved in Onychomycosis in Patients of a Spanish Rural Area

Marcos-Tejedor, Felix; Mota, Marta; Iglesias-Sánchez, María José; Mayordomo, Raquel; Gonçalves, Teresa, 2021. Journal of Fungi. 8. 7. 2021. http://dx.doi.org/10.3390/jof7080623 . 10.3390/jof7080623 . published Journal of Fungi

Candida Extracellular Nucleotide Metabolism Promotes Neutrophils Extracellular Traps Escape

Afonso, Mariana; Mestre, Ana Rita; Silva, Guilherme; Almeida, Ana Catarina; Cunha, Rodrigo A.; Meyer-Fernandes, José Roberto; Gonçalves, Teresa; Rodrigues, Lisa, 2021. Frontiers in Cellular and Infection Microbiology. 11. 2021. http://dx.doi.org/10.3389/fcimb.2021.678568 . 10.3389/fcimb.2021.678568 . published Frontiers in Cellular and Infection Microbiology

Pyomelanin Synthesis in Alternaria alternata Inhibits DHN-Melanin Synthesis and Decreases Cell Wall Chitin Content and Thickness

Fernandes, Chantal; Mota, Marta; Barros, Lillian; Dias, Maria Inês; Ferreira, Isabel C. F. R.; Piedade, Ana P.; Casadevall, Arturo; Gonçalves, Teresa, 2021. Frontiers in Microbiology. 12. 2021. http://dx.doi.org/10.3389/fmicb.2021.691433 . 10.3389/fmicb.2021.691433 . published Frontiers in Microbiology

The transcription factor Ndt80 is a repressor of Candida parapsilosis virulence attributes

Branco, Joana; Martins-Cruz, Cláudia; Rodrigues, Lisa; Silva, Raquel M.; Araújo-Gomes, Nuno; Gonçalves, Teresa; Miranda, Isabel M.; Rodrigues, Acácio G., 2021. Virulence. 601 - 614. 1. 12. 2021. http://dx.doi.org/10.1080/21505594.2021.1878743 . 10.1080/21505594.2021.1878743 . published Virulence

Retrospective study of group A Streptococcus oropharyngeal infection diagnosis using a rapid antigenic detection test in a paediatric population from the central region of Portugal

Mendes, Nuno; Miguéis, Carmo; Lindo, Jorge; Gonçalves, Teresa; Miguéis, António, 2021. European Journal of Clinical Microbiology & Infectious Diseases. 1235 - 1243. 6. 40. 2021. http://dx.doi.org/10.1007/s10096-021-04157-x . 10.1007/s10096-021-04157-x . published European Journal of Clinical Microbiology & Infectious Diseases

Evaluation of overtime phenotypic variation of yeasts in chronic vulvovaginal candidosis cases

Faria-Gonçalves, Paula; Gaspar, Carlos; Oliveira, Ana Sofia; Palmeira-de-Oliveira, Rita; Gonçalves, Teresa; Martinez-de-Oliveira, José; Palmeira-de-Oliveira, Ana; Rolo, Joana, 2021. Medical Mycology. 1166 - 1173. 12. 59. 2021. http://dx.doi.org/10.1093/mmy/myab048 . 10.1093/mmy/myab048 . published Medical Mycology

Synthesis, Characterization and Evaluation of the Antibacterial and Antitumor Activity of HalogenatedSalen Copper (II) Complexes derived from Camphoric Acid

Pires, Ana Salomé; Batista, João; Murtinho, Dina; Nogueira, Célia; Karamysheva, Anna; Luísa Ramos, M.; Milne, Bruce F.; et al, 2020. Applied Organometallic Chemistry. 5. 34. 2020. http://dx.doi.org/10.1002/aoc.5569 . 10.1002/aoc.5569 . published Applied Organometallic Chemistry

Evaluation of a novel dog animal model for peri-implant disease: clinical, radiographic, microbiological and histological assessment

Martins, Orlando; Ramos, João Carlos; Mota, Marta; Dard, Michel; Viegas, Carlos; Caramelo, Francisco; Nogueira, Célia; Gonçalves, Teresa; Baptista, Isabel Poiares, 2020. Clinical Oral Investigations. 3121 - 3132. 9. 24. 2020. http://dx.doi.org/10.1007/s00784-019-03186-3 . 10.1007/s00784-019-03186-3 . published Clinical Oral Investigations

Airborne route and bad use of ventilation systems as non-negligible factors in SARS-CoV-2 transmission

Correia, G.; Rodrigues, L.; Gameiro da Silva, M.; Gonçalves, T., 2020. Medical Hypotheses. 141. 2020. http://dx.doi.org/10.1016/j.mehy.2020.109781 . 10.1016/j.mehy.2020.109781 . published Medical Hypotheses

Recurrent vulvovaginal Candida spp isolates phenotypically express less virulence traits

Faria-Gonçalves, Paula; Rolo, Joana; Gaspar, Carlos; Oliveira, Ana Sofia; Pestana, Paula Gouveia; Palmeira-de-Oliveira, Rita; Gonçalves, Teresa; Martinez-de-Oliveira, José; Palmeira-de-Oliveira, Ana, 2020. Microbial Pathogenesis. 148. 2020. http://dx.doi.org/10.1016/j.micpath.2020.104471 . 10.1016/j.micpath.2020.104471 . published Microbial Pathogenesis

Preparation of gentamicin sulfate eluting fiber mats by emulsion and by suspension electrospinning

Coimbra, Patrícia; Freitas, João P.; Gonçalves, Teresa; Gil, Maria H.; Figueiredo, Margarida, 2019. Materials Science and Engineering: C. 86 - 93. 94. 2019. http://dx.doi.org/10.1016/j.msec.2018.09.019 . 10.1016/j.msec.2018.09.019 . published Materials Science and Engineering: C

Chitosan Plus Compound 48/80: Formulation and Preliminary Evaluation as a Hepatitis B Vaccine Adjuvant

Bento, Dulce; Jesus, Sandra; Lebre, Filipa; Gonçalves, Teresa; Borges, Olga, 2019. Pharmaceutics. 2. 11. 2019. http://dx.doi.org/10.3390/pharmaceutics11020072 . 10.3390/pharmaceutics11020072 . published Pharmaceutics

An Insight into Advanced Approaches for Photosensitizer Optimization in Endodontics—A Critical Review

Diogo, Patrícia; F. Faustino, M. Amparo; P. M. S. Neves, M. Graça; Palma, Paulo J.; P. Baptista, Isabel; Gonçalves, Teresa; Santos, João Miguel, 2019. Journal of Functional Biomaterials. 4. 10. 2019. http://dx.doi.org/10.3390/jfb10040044 . 10.3390/jfb10040044 . published Journal of Functional Biomaterials

Early Interaction of Alternaria infectoria Conidia with Macrophages

Almeida, M. C.; Antunes, D.; Silva, B. M. A.; Rodrigues, L.; Mota, M.; Borges, O.; Fernandes, C.; Gonçalves, T., 2019. Mycopathologia. 383 - 392. 3. 184. 2019. http://dx.doi.org/10.1007/s11046-019-00339-6 . 10.1007/s11046-019-00339-6 . published Mycopathologia

Is the chlorophyll derivative Zn(II)e 6 Me a good photosensitizer to be used in root canal disinfection?

Diogo, Patrícia; Mota, Marta; Fernandes, Chantal; Sequeira, Diana; Palma, Paulo; Caramelo, Francisco; Neves, M. Graça P.M.S.; et al, 2018. Photodiagnosis and Photodynamic Therapy. 205 - 211. 22. 2018. http://dx.doi.org/10.1016/j.pdpdt.2018.04.009 . 10.1016/j.pdpdt.2018.04.009 . published Photodiagnosis and Photodynamic Therapy

Intestinal Microbial and Metabolic Profiling of Mice Fed with High-Glucose and High-Fructose Diets

Silva, João C. P.; Mota, Marta; Martins, Fátima O.; Nogueira, Célia; Gonçalves, Teresa; Carneiro, Tatiana; Pinto, Joana; et al, 2018. Journal of Proteome Research. 2880 - 2891. 8. 17. 2018. http://dx.doi.org/10.1021/acs.jproteome.8b00354 . 10.1021/acs.jproteome.8b00354 . published Journal of Proteome Research

The antifungal activity of extracts of Osmundea pinnatifida, an edible seaweed, indicates its usage as a safe environmental fungicide or as a food additive preventing post-harvest fungal food contamination

Silva, Paulo; Fernandes, Chantal; Barros, Lillian; Ferreira, Isabel C. F. R.; Pereira, Leonel; Gonçalves, Teresa, 2018. Food & Function. 6187 - 6195. 12. 9. 2018. http://dx.doi.org/10.1039/c8fo01797b . 10.1039/c8fo01797b . published Food & Function

Antimicrobial Photodynamic Therapy against Endodontic Enterococcus faecalis and Candida albicans Mono and Mixed Biofilms in the Presence of Photosensitizers: A Comparative Study with Classical Endodontic Irrigants

Diogo, Patrícia; Fernandes, Chantal; Caramelo, Francisco; Mota, Marta; Miranda, Isabel M.; Faustino, M. A. F.; Neves, M. G. P. M. S.; et al, 2017. Frontiers in Microbiology. 8. 2017. http://dx.doi.org/10.3389/fmicb.2017.00498 . 10.3389/fmicb.2017.00498 . Frontiers in Microbiology

Type 1 diabetes in children is not a predisposing factor for oral yeast colonization.

Costa AL; Silva BM; Soares R; Mota D; Alves V; Mirante A; Ramos JC; et al, 2016. 2016. http://europepmc.org/abstract/med/27664993 .

Activation of Melanin Synthesis in Alternaria infectoria by Antifungal Drugs

Fernandes, Chantal; Prados-Rosales, Rafael; Silva, Branca M. A.; Nakouzi-Naranjo, Antonio; Zuzarte, Mónica; Chatterjee, Subhasish; Stark, Ruth E.; Casadevall, Arturo; Gonçalves, Teresa, 2016. Antimicrobial Agents and Chemotherapy. 1646 - 1655. 3. 60. 2016. http://dx.doi.org/10.1128/aac.02190-15 . 10.1128/aac.02190-15 . published Antimicrobial Agents and Chemotherapy

HIV1-viral protein R (Vpr) mutations: associated phenotypes and relevance for clinical pathologies

Soares, Rui; Rocha, Graça; Meliço-Silvestre, António; Gonçalves, Teresa, 2016. Reviews in Medical Virology. 314 - 329. 5. 26. 2016. http://dx.doi.org/10.1002/rmv.1889 . 10.1002/rmv.1889 . published Reviews in Medical Virology

Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly

Rodrigues, Lisa; Miranda, Isabel M.; Andrade, Geanne M.; Mota, Marta; Cortes, Luísa; Rodrigues, Acácio G.; Cunha, Rodrigo A.; Gonçalves, Teresa, 2016. Oncotarget. 62862 - 62872. 39. 7. 2016. http://dx.doi.org/10.18632/oncotarget.11760 . 10.18632/oncotarget.11760 . published Oncotarget

The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi

Fernandes, Chantal; Gow, Neil A.R.; Gonçalves, Teresa, 2016. Fungal Biology Reviews. 1 - 14. 1. 30. 2016. http://dx.doi.org/10.1016/j.fbr.2016.03.002 . 10.1016/j.fbr.2016.03.002 . published Fungal Biology Reviews

Chlorhexidine Mouthwash Affects Plaque and Saliva¿s Bacterial Counts of Diabetics

Coelho, Ana Sofia; Paula, Anabela; Caramelo, Francisco; Carrilho, Francisco; Melo, Miguel; Barros, Luísa; Batista, Carla; et al, 2016. International Dental Journal. 164 - 183. 66. 2016. http://dx.doi.org/10.1111/idj.12269 . 10.1111/idj.12269 . International Dental Journal

Antifungal activity of carrageenan extracts from the red alga Chondracanthus teedei var. lusitanicus

Soares, Fabiana; Fernandes, Chantal; Silva, Paulo; Pereira, Leonel; Gonçalves, Teresa, 2016. Journal of Applied Phycology. 2991 - 2998. 5. 28. 2016. http://dx.doi.org/10.1007/s10811-016-0849-9 . 10.1007/s10811-016-0849-9 . Journal of Applied Phycology

Type 1 diabetes in children is not a predisposing factor for oral yeast colonization

Costa, Ana L.; Silva, Branca M.A.; Soares, Rui; Mota, Diana; Alves, Vera; Mirante, Alice; Ramos, João C.; et al, 2016. Medical Mycology. 4. 55. 2016. http://dx.doi.org/10.1093/mmy/myw092 . 10.1093/mmy/myw092 . Medical Mycology

Characterization of extracellular nucleotide metabolism inCandida albicans

Rodrigues, Lisa; Russo-Abrahão, Thais; Cunha, Rodrigo A.; Gonçalves, Teresa; Meyer-Fernandes, José Roberto, 2015. FEMS Microbiology Letters. 1. 363. 2015. http://dx.doi.org/10.1093/femsle/fnv212 . 10.1093/femsle/fnv212 . published FEMS Microbiology Letters

Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism

George, Jimmy; Gonçalves, Francisco Q.; Cristóvão, Gonçalo; Rodrigues, Lisa; Meyer Fernandes, José Roberto; Gonçalves, Teresa; Cunha, Rodrigo A.; Gomes, Catarina A., 2015. Glia. 1636 - 1645. 9. 63. 2015. http://dx.doi.org/10.1002/glia.22833 . 10.1002/glia.22833 . published Glia

Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity

Bento, D.; Staats, H.F.; Gonçalves, T.; Borges, O., 2015. European Journal of Pharmaceutics and Biopharmaceutics. 149 - 164. 93. 2015. http://dx.doi.org/10.1016/j.ejpb.2015.03.024 . 10.1016/j.ejpb.2015.03.024 . published European Journal of Pharmaceutics and Biopharmaceutics

Macrophage Mitochondrial and Stress Response to Ingestion ofCryptococcus neoformans

Coelho, Carolina; Souza, Ana Camila Oliveira; Derengowski, Lorena da Silveira; de Leon-Rodriguez, Carlos; Wang, Bo; Leon-Rivera, Rosiris; Bocca, Anamelia Lorenzetti; Gonçalves, Teresa; Casadevall, Arturo, 2015. The Journal of Immunology. 2345 - 2357. 5. 194. 2015. http://dx.doi.org/10.4049/jimmunol.1402350 . 10.4049/jimmunol.1402350 . The Journal of Immunology

Photodynamic Antimicrobial Chemotherapy for Root Canal System Asepsis: A Narrative Literature Review

Diogo, P.; Gonçalves, T.; Palma, P.; Santos, J. M., 2015. International Journal of Dentistry. 1 - 26. 2015. 2015. http://dx.doi.org/10.1155/2015/269205 . 10.1155/2015/269205 . International Journal of Dentistry

Modulation of alternaria infectoria cell wall chitin and glucan synthesis by cell wall synthase inhibitors

Fernandes, C.; Anjos, J.; Walker, L.A.; Silva, B.M.A.; Cortes, L.; Mota, M.; Munro, C.A.; et al, 2014. Antimicrobial Agents and Chemotherapy. 2894 - 2904. 5. 58. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898619019&partnerID=MN8TOARS . 10.1128/AAC.02647-13 . Antimicrobial Agents and Chemotherapy

Characterization of Alternaria infectoria extracellular vesicles

Silva, B. M. A.; Prados-Rosales, R.; Espadas-Moreno, J.; Wolf, J. M.; Luque-Garcia, J. L.; Goncalves, T.; Casadevall, A., 2013. Medical Mycology. 202 - 210. 2. 52. 2013. http://dx.doi.org/10.1093/mmy/myt003 . 10.1093/mmy/myt003 . Medical Mycology

Candida albicans CUG Mistranslation Is a Mechanism To Create Cell Surface Variation

Miranda, Isabel; Silva-Dias, Ana; Rocha, Rita; Teixeira-Santos, Rita; Coelho, Carolina; Gonçalves, Teresa; Santos, Manuel A. S.; et al, 2013. mBio. 4. 4. 2013. http://dx.doi.org/10.1128/mbio.00285-13 . 10.1128/mbio.00285-13 . mBio

Ozone action on Streptococcus mutans and Lactobacillus fermentum: A pilot study

Marques, Joana; Paula, Anabela; Gonçalves, Teresa; Ferreira, Manuel Marques; Carrilho, Eunice, 2013. World Journal of Stomatology. 18 - 23. 1. 2. 2013. 10.5321/wjs.v2.i1.18 . published World Journal of Stomatology

Validation of a New 96-Well Plate Spectrophotometric Method for the Quantification of Compound 48/80 Associated with Particles

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