Ana Reis-Costa

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PhD Student

Metabolic Control

Overview

I am a young Portuguese researcher who is interested in energy metabolism and cell regulation. I finished my Bachelor's degree in Biochemistry in 2017 and my Master's degree in Cellular and Molecular Biology in 2020, both at the University of Coimbra. During this period, I worked mostly on understanding the hepatic metabolic dysregulation during Non-Alcoholic Fatty Liver Disease. This work led to seven poster presentations (two 1st authorships), one oral communication (1st authorship), one journal article (co-authorship) and my dissertation titled The impact of different lipogenic diets on direct and indirect pathway contributions to hepatic glycogen synthesis. In March 2021, I started working as a Research Fellow at the University of Florence. There, I studied the interaction of the microbiome with host metabolism, having done an oral communication that led to a conference paper (1st authorship). I am currently starting my PhD at CNC focused on adipose tissue dysfunction in the context of Type 2 Diabetes.

Publications

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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

Investigating Yeast–Lactobacilli Interactions through Co-Culture Growth and Metabolite Analysis

Stefano Nenciarini; Ana Reis-Costa; Marco Pallecchi; Sonia Renzi; Aldo D’Alessandro; Agnese Gori; Benedetta Cerasuolo; et al, Fermentation. 2023. https://doi.org/10.3390/fermentation9110933 . 10.3390/fermentation9110933 . Fermentation

O impacto de diferentes dietas lipogénicas na síntese de glicogénio no contexto da doença de Fígado Gordo Não Alcoólico

Reis-Costa, Ana; Belew, Getachew Debas; Barosa, C.; Ivan Viegas; Ludgero Tavares; Jones, John, 19º Congresso Português de Diabetes. 16-03-2023.

The impact of lifestyle in Non-Alcoholic Fatty liver disease – Why you should be concerned about your eating habits and the origin of your foods

Reis-Costa, Ana; Belew, Getachew Debas; Ludgero Tavares; Francesco Vitali; Agnese Gori; Giovanni Bacci; Carlotta De Filippo; Duccio Cavalieri; John Griffith Jones, 04-11-2022.

Semantics of Dairy Fermented Foods: A Microbiologist’s Perspective

Foods. 1939 - 1939. 13. 11. 2022. http://dx.doi.org/10.3390/foods11131939 . 10.3390/foods11131939 . Foods

Peripheral dopamine directly acts on insulin sensitive tissue to regulate insulin signalling and metabolic function

Tavares, Gabriela; Marques, Daniela; Reis-Costa, Ana; Barra, Cátia; Tiago Rodrigues; Joana F. Sacramento; Melo, Bernardete F.; et al, 55th Annual Scientific Meeting of European Society for Clinical Investigation (ESCI), virtual meeting, 2021. 05-07-2021.

ONS modelling of diet concepts: further development required by the objective definition of "western diet"

Reis-Costa, Ana; Francesco Vitali; Agnese Gori; Giovanni Bacci; Carlotta De Filippo; Duccio Cavalieri, Bolzano, Italy. 18-09-2021. published

The impact of different lipogenic diets on indirect pathway contributions to hepatic glycogen synthesis

Reis-Costa, Ana; Belew, Getachew Debas; Ludgero Tavares; Meneses, Maria João; Jones, John, 30-09-2021.

Dopamine D2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes

Tavares, Gabriela; Marques, Daniela; Barra, Cátia; Rosendo-Silva, Daniela; Reis-Costa, Ana; Tiago Rodrigues; Patricia Gasparini; et al, Molecular Metabolism. 101241. 51. 2021. http://dx.doi.org/10.1016/j.molmet.2021.101241 . 10.1016/j.molmet.2021.101241 . published Molecular Metabolism

The impact of different lipogenic diets on direct and indirect pathway contributions to hepatic glycogen synthesis

Costa, Ana Maria Reis, master. Universidade de Coimbra Faculdade de Ciencias e Tecnologia . 18-12-2020. http://hdl.handle.net/10316/94040 .

The Impact of High-Fat Feeding on Direct and Indirect Pathway Contributions to Hepatic Glycogen Synthesis in a Mouse Model of Non-Alcoholic Fatty Liver Disease

Reis-Costa, Ana; Belew, Getachew Debas; Cristina Barosa; Ivan Viegas; Ludgero Tavares; Jones, John, 54th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) | COVID-19 Edition. 23-09-2020.

Alterações na lipogénese de novo hepática em murganhos submetidos ao xarope HFCS-55 rico em frutose

Costa, Ana; Giada di Nunzio; Belew, Getachew Debas; Torres, Alejandra; Ludgero Tavares; Jones, John, 16º Congresso Português de Diabetes. 06-03-2020.

Bromocriptine decreases hepatic steatosis by modulation of the dopamine signaling in liver

Barra, Cátia; Reis-Costa, Ana; Tavares, Gabriela; Marques, Daniela; Tiago Rodrigues; Joana F. Sacramento; Melo, Bernardete F.; et al, 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI). 05-2019.

A bromocriptina reduz a esteatose hepática por modulação da sinalização dopaminérgica no fígado

Barra, Cátia; Reis-Costa, Ana; Tavares, Gabriela; Marques, Daniela; Tiago Rodrigues; Joana F. Sacramento; Melo, Bernardete F.; et al, 15º Congresso Português de Diabetes (SPD). 03-2019.

Modulation of dopaminergic signalling with Bromocriptine improves glucose and lipid metabolism in white and brown adipose tissue in a type 2 diabetic obese animal model

Tavares, Gabriela; Marques, Daniela; Barra, Cátia; Reis-Costa, Ana; Tiago Rodrigues; Joana F. Sacramento; Melo, Bernardete F.; et al, 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI). 05-2019.

Modulation of dopaminergic signaling with bromocriptine improves glucose and lipid metabolism in an obese type 2 diabetic animal model

Tavares, Gabriela; Marques, Daniela; Costa, Ana; Barra, Cátia; Tiago Rodrigues; Joana F. Sacramento; Melo, Bernardete F.; et al, 55th Annual Meeting of the European Association for the Study of Diabetes Meeting (EASD). 16-09-2019.

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2022/11/01 -

The role of exogenous and endogenous fructose turnover in adipose tissue dysfunction during the development of Type 2 Diabetes

2022.10983.BD

PhD Student Fellow

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade de Coimbra Instituto de Investigação Interdisciplinar; Uppsala Universitet; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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