Barbara da Silva Rocha

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Publications

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Information about journal articles, updated at 03-11-2024, from platform CIÊNCIAVITAE.

Are oral and gut microbiota communicating through redox pathways? A novel asset of the nitrate-nitrite-NO pathway

Paiva, Beatriz; Laranjinha, João; Rocha, Barbara S, FEBS Letters. 2024. in press FEBS Letters

Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis

Gonçalves, João S.; Marçal, Ana L.; Marques, Bárbara S.; Costa, Filipa D.; Laranjinha, João; Rocha, Bárbara S.; Lourenço, Cátia F., Biochemical Society Transactions. 2024. http://dx.doi.org/10.1042/bst20230491 . 10.1042/bst20230491 . Biochemical Society Transactions

Dietary (poly)phenols as modulators of the biophysical properties in endothelial cell membranes: its impact on nitric oxide bioavailability in hypertension

Reis, Ana; Rocha, Barbara S.; Laranjinha, João; de Freitas, Victor, FEBS Letters. 2024. http://dx.doi.org/10.1002/1873-3468.14812 . 10.1002/1873-3468.14812 . FEBS Letters

Epigenetic Modifications Induced by the Gut Microbiota May Result from What We Eat: Should We Talk about Precision Diet in Health and Disease?

Reva, Katerina; Laranjinha, João; Rocha, Bárbara S., Metabolites. 3. 13. 2023. http://dx.doi.org/10.3390/metabo13030375 . 10.3390/metabo13030375 . Metabolites

(Poly)phenols and nitrolipids: Relevant participants in nitric oxide metabolism

Fraga, César G.; Trostchansky, Andrés; Rocha, Barbara S.; Laranjinha, João; Rubbo, Homero; Galleano, Monica, Molecular Aspects of Medicine. 89. 2023. http://dx.doi.org/10.1016/j.mam.2022.101158 . 10.1016/j.mam.2022.101158 . Molecular Aspects of Medicine

Precision diet: tuning human gut microbiota to modulate epigenetic modifications in health and disease

Rocha, Barbara S; 3014-5272-6F5D, European Journal of Nutrition. 2022. under revision European Journal of Nutrition

Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery

Ahmed, W. U. R.; Bhatia, S.; McLean, K. A.; Khaw, R.; Baker, D.; Kamarajah, S. K.; Bell, S.; et al, BJS Open. 1. 6. 2022. http://dx.doi.org/10.1093/bjsopen/zrab150 . 10.1093/bjsopen/zrab150 . BJS Open

The LIFEwithIBD Intervention: Study Protocol for a Randomized Controlled Trial of a Face-to-Face Acceptance and Commitment Therapy and Compassion-Based Intervention Tailored to People With Inflammatory Bowel Disease

Trindade, Inês A.; Pereira, Joana; Galhardo, Ana; Ferreira, Nuno B.; Lucena-Santos, Paola; Carvalho, Sérgio A.; Oliveira, Sara; et al, Frontiers in Psychiatry. 12. 2021. http://dx.doi.org/10.3389/fpsyt.2021.699367 . 10.3389/fpsyt.2021.699367 . Frontiers in Psychiatry

The Nitrate-Nitrite-Nitric Oxide Pathway on Healthy Ageing: A Review of Pre-clinical and Clinical Data on the Impact of Dietary Nitrate in the Elderly

Rocha, Bárbara S., Frontiers in Aging. 2. 2021. http://dx.doi.org/10.3389/fragi.2021.778467 . 10.3389/fragi.2021.778467 . Frontiers in Aging

The Peculiar Facets of Nitric Oxide as a Cellular Messenger: From Disease-Associated Signaling to the Regulation of Brain Bioenergetics and Neurovascular Coupling

Laranjinha, João; Nunes, Carla; Ledo, Ana; Lourenço, Cátia; Rocha, Bárbara; Barbosa, Rui M., Neurochemical Research. 2021. http://dx.doi.org/10.1007/s11064-020-03015-0 . 10.1007/s11064-020-03015-0 . Neurochemical Research

Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study

Glasbey, JC; Bibi, S; Pata, F; Ozkan, BB; Van Straten, S; Hodson, J; Chapman, SJ; et al, Colorectal Disease. 2288 - 2297. 12. 22. 2020. http://dx.doi.org/10.1111/codi.15311 . 10.1111/codi.15311 . Colorectal Disease

Safety of hospital discharge before return of bowel function after elective colorectal surgery

Chapman, S J; Blanco-Colino, R; Pérez-Ajates, S; Bautista, O Anabitarte; Hodson, J; Glasbey, J C; Pata, F; et al, British Journal of Surgery. 552 - 559. 5. 107. 2020. http://dx.doi.org/10.1002/bjs.11422 . 10.1002/bjs.11422 . British Journal of Surgery

Nitrate from diet might fuel gut microbiota metabolism: Minding the gap between redox signaling and inter-kingdom communication

Rocha, Bárbara S.; Laranjinha, João, Free Radical Biology and Medicine. 37 - 43. 149. 2020. http://dx.doi.org/10.1016/j.freeradbiomed.2020.02.001 . 10.1016/j.freeradbiomed.2020.02.001 . Free Radical Biology and Medicine

Inorganic nitrate prevents the loss of tight junction proteins and modulates inflammatory events induced by broad-spectrum antibiotics: A role for intestinal microbiota?

Rocha, Bárbara S.; Correia, Mariana G.; Pereira, Anabela; Henriques, Isabel; Da Silva, Gabriela J.; Laranjinha, João, Nitric Oxide. 27 - 34. 88. 2019. http://dx.doi.org/10.1016/j.niox.2019.04.001 . 10.1016/j.niox.2019.04.001 . Nitric Oxide

Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

Chapman, SJ; Clerc, D; Blanco-Colino, R; Otto, A; Nepogodiev, D; Pagano, G; Schaeff, V; et al, British Journal of Surgery. 2019. http://dx.doi.org/10.1002/bjs.11326 . 10.1002/bjs.11326 . British Journal of Surgery

Role of nitrite, urate and pepsin in the gastroprotective effects of saliva

Rocha, Bárbara S.; Lundberg, Jon O; Radi, Rafael; Laranjinha, João, Redox Biology. 407 - 414. 8. 2016. http://dx.doi.org/10.1016/j.redox.2016.04.002 . 10.1016/j.redox.2016.04.002 . Redox Biology

Dietary nitrite induces occludin nitration in the stomach

Rocha, Bárbara S.; Correia, Mariana G.; Fernandes, Rita C.; Gonçalves, João S.; Laranjinha, João, Free Radical Research. 1257 - 1264. 11. 50. 2016. http://dx.doi.org/10.1080/10715762.2016.1234049 . 10.1080/10715762.2016.1234049 . Free Radical Research

Tuning constitutive and pathological inflammation in the gut via the interaction of dietary nitrate and polyphenols with host microbiome

Rocha, Bárbara S.; Nunes, Carla; Laranjinha, João, The International Journal of Biochemistry & Cell Biology. 393 - 402. 81. 2016. http://dx.doi.org/10.1016/j.biocel.2016.10.021 . 10.1016/j.biocel.2016.10.021 . The International Journal of Biochemistry & Cell Biology

Ethyl nitrite is produced in the human stomach from dietary nitrate and ethanol, releasing nitric oxide at physiological pH: potential impact on gastric motility

Rocha, Bárbara S.; Gago, Bruno; Barbosa, Rui M.; Cavaleiro, Carlos; Laranjinha, João, Free Radical Biology and Medicine. 160 - 166. 82. 2015. http://dx.doi.org/10.1016/j.freeradbiomed.2015.01.021 . 10.1016/j.freeradbiomed.2015.01.021 . Free Radical Biology and Medicine

A shortcut to wide-ranging biological actions of dietary polyphenols: modulation of the nitrate–nitrite–nitric oxide pathway in the gut

Rocha, Bárbara S.; Nunes, Carla; Pereira, Cassilda; Barbosa, Rui M.; Laranjinha, João, Food & Function. 1646 - 1652. 8. 5. 2014. http://dx.doi.org/10.1039/c4fo00124a . 10.1039/c4fo00124a . Food & Function

Pepsin is nitrated in the rat stomach, acquiring antiulcerogenic activity: A novel interaction between dietary nitrate and gut proteins

Rocha, Bárbara S.; Gago, Bruno; Barbosa, Rui M.; Lundberg, Jon O.; Mann, Giovanni E.; Radi, Rafael; Laranjinha, João, Free Radical Biology and Medicine. 26 - 34. 58. 2013. http://dx.doi.org/10.1016/j.freeradbiomed.2012.12.017 . 10.1016/j.freeradbiomed.2012.12.017 . Free Radical Biology and Medicine

The redox interplay between nitrite and nitric oxide: From the gut to the brain

Pereira, Cassilda; Ferreira, Nuno R.; Rocha, Bárbara S.; Barbosa, Rui M.; Laranjinha, João, Redox Biology. 276 - 284. 1. 1. 2013. http://dx.doi.org/10.1016/j.redox.2013.04.004 . 10.1016/j.redox.2013.04.004 . Redox Biology

Intragastric nitration by dietary nitrite: Implications for modulation of protein and lipid signaling

Rocha, Bárbara S.; Gago, Bruno; Barbosa, Rui M.; Lundberg, Jon O.; Radi, Rafael; Laranjinha, João, Free Radical Biology and Medicine. 693 - 698. 3. 52. 2012. http://dx.doi.org/10.1016/j.freeradbiomed.2011.11.011 . 10.1016/j.freeradbiomed.2011.11.011 . Free Radical Biology and Medicine

Dietary Nitrite in Nitric Oxide Biology: A Redox Interplay with Implications for Pathophysiology and Therapeutics

S. Rocha, Barbara; Gago, Bruno; Pereira, Cassilda; M. Barbosa, Rui; Bartesaghi, Silvina; O. Lundberg, Jon; Radi, Rafael; Laranjinha, Joao, Current Drug Targets. 1351 - 1363. 9. 12. 2011. http://dx.doi.org/10.2174/138945011796150334 . 10.2174/138945011796150334 . Current Drug Targets

Diffusion of nitric oxide through the gastric wall upon reduction of nitrite by red wine: Physiological impact

Rocha, Bárbara S.; Gago, Bruno; Barbosa, Rui M.; Laranjinha, João, Nitric Oxide. 235 - 241. 3. 22. 2010. http://dx.doi.org/10.1016/j.niox.2010.01.003 . 10.1016/j.niox.2010.01.003 . Nitric Oxide

Dietary polyphenols generate nitric oxide from nitrite in the stomach and induce smooth muscle relaxation

Rocha, Bárbara S.; Gago, Bruno; Barbosa, Rui M.; Laranjinha, João, Toxicology. 41 - 48. 1-2. 265. 2009. http://dx.doi.org/10.1016/j.tox.2009.09.008 . 10.1016/j.tox.2009.09.008 . Toxicology

The potent vasodilator ethyl nitrite is formed upon reaction of nitrite and ethanol under gastric conditions

Gago, Bruno; Nyström, Thomas; Cavaleiro, Carlos; Rocha, Bárbara S.; Barbosa, Rui M.; Laranjinha, João; Lundberg, Jon O., Free Radical Biology and Medicine. 404 - 412. 4. 45. 2008. http://dx.doi.org/10.1016/j.freeradbiomed.2008.04.027 . 10.1016/j.freeradbiomed.2008.04.027 . Free Radical Biology and Medicine

All projects

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Information of exclusive responsibility of the researcher 03-11-2024 , from platform CIÊNCIAVITAE.

2023/03/01 - 2026/02/28

The Neurovascular Coupling as a biomarker and a target for cognitive enhancement in aging and vascular dementia through an innovative dietary nitrate-driven nitric oxide redox cycle: a translational study

2022.05454.PTDC

Researcher

Fundação para a Ciência e a Tecnologia

2022/05/01 - 2023/12/01

The impact of redox signaling on microbiota-gut-brain communication: sheding light on how dietary nitrate signals from the gut to the brain

ECR-2022

Principal investigator

The Oxygen Club of California; Society for Free Radical Biology and Medicine - Europe

2021/01/01 - 2025/12/31

Center for Innovative Biomedicine and Biotechnology - Associate Laboratory

LA/P/0058/2020

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2021/03/15 - 2024/03/14

Helicobacter Pylori Eradication Therapy in Portugal: Prospective, randomized, blind and multicentre trial on the efficacy of quadruple therapies and their clinical impact and immunological, oral and gut microbiota changes

PTDC/MEC-GAS/7361/2020

Researcher

2019/01/01 - 2019/12/31

CNC. IBILI

UID/NEU/04539/2019

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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