Publications
Information about journal articles, updated at 17-11-2024, from platform CIÊNCIAVITAE.
MESENCHYMAL STROMAL CELLS THERAPY RESCUES MITOPHAGY IN MACHADO-JOSEPH DISEASE MODELS
Da Silva, Antonio; Barros, Ines; Lobo, Diana; Gonzaga, Daniela; de Almeida, Luis Pereira; Miranda, Catarina Oliveira, Medicine. 2023. https://publons.com/wos-op/publon/62508932/ . Medicine
<i>In Vitro</i>??????? Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue Regeneration
Pereira, Patricia; Neto, Ana S.; Rodrigues, Ana S.; Barros, Ines; Miranda, Catarina; Ramalho-Santos, Joao; Pereira de Almeida, Luis; et al, Polymers. 2023. https://publons.com/wos-op/publon/61175927/ . 10.3390/POLYM15102256 . Polymers
ALTERED TIGHT JUNCTION-ASSOCIATED PROTEINS SUBCELLULAR LOCALIZATION IN MACHADO-JOSEPH DISEASE/SPINOCEREBELLAR ATAXIA TYPE 3
Barros, Ines; Gonzaga, Daniela; Lobo, Diana; Nobre, Rui Jorge; Martins, Ines; Silva, Antonio; Duarte, Sonia; De Almeida, Luis Pereira; Miranda, Catarina Oliveira, Medicine. 2023. https://publons.com/wos-op/publon/62700610/ . Medicine
Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis
Almeida, Sara F. F.; Fonseca, Alexandra; Sereno, Jose; Ferreira, Hugo R. S.; Lapo-Pais, Mariana; Martins-Marques, Tania; Rodrigues, Teresa; et al, Small. 2022. https://publons.com/wos-op/publon/54945209/ . 10.1002/SMLL.202203999 . Small
Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis
Almeida, Sara F.F.; Fonseca, Alexandra; Sereno, José; Ferreira, Hugo R. S.; Lapo-Pais, Mariana; Martins-Marques, Tânia; Rodrigues, Teresa; et al, Small. 49. 18. 2022. http://dx.doi.org/10.1002/smll.202203999 . 10.1002/smll.202203999 . Small
Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease.
Miranda CO*, Acta Neuropathologica Communications. Accepted for publication on February 9, 2022. . 2022. 10.1186/s40478-022-01329-4 . Acta Neuropathologica Communications. Accepted for publication on February 9, 2022.
Cerebellar morphometric and spectroscopic biomarkers of Machado-Joseph Disease correlate with motor behaviour in a transgenic mouse model and show similar profiles in human patients. UNDER REVISION
Miranda, Catarina; Nobre, Rui Jorge; Paiva, Vitor Hugo; João Duarte; Castelhano, João; Petrella, Lorena; Sereno, José; et al, 2021. under revision
Highly Porous Composite Scaffolds Endowed with Antibacterial Activity for Multifunctional Grafts in Bone Repair
Neto, Ana S.; Pereira, Patrícia; Fonseca, Ana C.; Dias, Carla; Almeida, Mariana C.; Barros, Inês; Miranda, Catarina O.; et al, Polymers. 24. 13. 2021. http://dx.doi.org/10.3390/polym13244378 . 10.3390/polym13244378 . Polymers
Mesenchymal stem cells for lysosomal storage and polyglutamine disorders: Possible shared mechanisms
Catarina Miranda, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13707 . 10.1111/eci.13707 . European Journal of Clinical Investigation
Blood-brain barrier (BBB) disruption is a shared feature for several neurodegenerative diseases
Oliveira Miranda, C.; Duarte Lobo, D.; Jorge Nobre, R.; Gonzaga, D.; Ines Barros, M.; Ines Martins, M.; Castelhano, J.; et al, European Journal of Clinical Investigation. 2021. https://publons.com/publon/49564552/ . European Journal of Clinical Investigation
Mesenchymal Stromal Cells’ Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go?
Barros, Inês; Marcelo, Adriana; Silva, Teresa P.; Barata, João; Rufino-Ramos, David; Pereira de Almeida, Luís; Miranda, Catarina O., Frontiers in Cellular Neuroscience. 14. 2020. http://dx.doi.org/10.3389/fncel.2020.584277 . 10.3389/fncel.2020.584277 . Frontiers in Cellular Neuroscience
Mesenchymal stromal cells to fight SARS-CoV-2: Taking advantage of a pleiotropic therapy
Barros, Inês; Silva, António; de Almeida, Luís Pereira; Miranda, Catarina Oliveira, Cytokine & Growth Factor Reviews. 2020. http://dx.doi.org/10.1016/j.cytogfr.2020.12.002 . 10.1016/j.cytogfr.2020.12.002 . Cytokine & Growth Factor Reviews
Allele-Specific AAV-Based Silencing of Mutant Ataxin-3 Alleviates Neuropathology and Motor Deficits in Spinocerebellar Ataxia Type 3
Nobre, Rui Jorge; Saraiva, Joana; Santana, Magda; Fusco, Clelia; Paixao, Susana; Miranda, Catarina; Petrella, Lorena; et al, Molecular Therapy. 2020. https://publons.com/publon/39930949/ . Molecular Therapy
The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples
Duarte Lobo, Diana; Nobre, Rui Jorge; Oliveira Miranda, Catarina; Pereira, Dina; Castelhano, João; Sereno, José; Koeppen, Arnulf; Castelo-Branco, Miguel; Pereira de Almeida, Luís, Acta Neuropathologica Communications. 1. 8. 2020. http://dx.doi.org/10.1186/s40478-020-00955-0 . 10.1186/s40478-020-00955-0 . Acta Neuropathologica Communications
Blood-brain barrier dysfunction as a neuropathological feature in Machado-Joseph Disease: results from human and mouse samples
Diana Lobo; Rui Nobre; Catarina Miranda; Dina Pereira; João Castelhano; José Sereno; Miguel Castelo-Branco; Luís De Almeida, Frontiers in Cellular Neuroscience. 2019. https://publons.com/publon/49522352/ . 10.3389/CONF.FNCEL.2019.01.00022 . Frontiers in Cellular Neuroscience
CRISPR-Cas9-Mediated Pre-Transcriptional Silencing of Mutant ATXN3 Decreases Motor Impairments of an In Vivo Machado-Joseph Disease Model
Matos, Carlos; Pena, Frederico; Conceicao, Andre; Lopes, Sara; Duarte, Sonia; Miranda, Catarina; de Almeida, Luis Pereira, Molecular Therapy. 2019. https://publons.com/publon/21742534/ . Molecular Therapy
Autophagy activation induced by let-7 microRNA overexpression counteracts disease phenotype in Machado-Joseph disease mouse models
Sónia Duarte; Beatriz Estremores; Janete Cunha-Santos; Catarina Miranda; João Barata; Albert La Spada; Luis De Almeida, Frontiers in Cellular Neuroscience. 2019. https://publons.com/publon/49522345/ . 10.3389/CONF.FNCEL.2019.01.00026 . Frontiers in Cellular Neuroscience
CRISPR interference-mediated silencing of mutant ATXN3 decreases motor impairments of an in vivo Machado-Joseph disease model
Matos, Carlos; Pena, Frederico; Conceicao, Andre; Lopes, Sara; Duarte, Sonia; Miranda, Catarina; de Almeida, Luis Pereira, European Journal of Clinical Investigation. 2019. https://publons.com/publon/28984641/ . European Journal of Clinical Investigation
A miRNA-based gene therapy approach to knock-down mutant ATXN3: Alleviation of Machado-Joseph disease phenotype in two mouse models upon two routes of administration
Nobre, Rui Jorge; Saraiva, Joana; Fusco, Clelia; Paixao, Susana; Santana, Magda; Miranda, Catarina; Petrella, Lorena; et al, European Journal of Clinical Investigation. 2019. https://publons.com/publon/39930960/ . European Journal of Clinical Investigation
Repeated transplantation of mesenchymal stromal cells in Machado-Joseph disease/Spinocerebellar ataxia type-3 mice can sustainably alleviate phenotypic symptoms and ameliorations can be monitored through magnetic resonance spectroscopy
Miranda, Catarina Oliveira; Marcelo, Adriana; Silva, Teresa Pereira; Barata, Joao; Vasconcelos-Ferreira, Ana; Pereira, Dina; Duarte, Sonia; et al, European Journal of Clinical Investigation. 2019. https://publons.com/publon/28984639/ . European Journal of Clinical Investigation
Non-invasive and allele-specific silencing therapy for Polyglutamine disorders: the case of Machado-Joseph disease/Spinocerebellar ataxia type 3
Rui Nobre; Joana Saraiva; Susana Paixão; Cellia Fusco; Magda Santana; Catarina Miranda; Lorena Petrella; et al, Frontiers in Cellular Neuroscience. 2019. https://publons.com/publon/49522350/ . 10.3389/CONF.FNCEL.2019.01.00007 . Frontiers in Cellular Neuroscience
Upregulation of let-7 microrna in mouse models of Machado-Joseph disease ameliorates neuropathology and motor phenotype
Duarte, Sonia Patricia; Estremores, Beatriz; Cunha-Santos, Janete; Miranda, Catarina; Barata, Joao; La Spada, Albert; de Almeida, Luis Pereira, European Journal of Clinical Investigation. 2019. https://publons.com/publon/28984643/ . European Journal of Clinical Investigation
Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease
Oliveira Miranda, Catarina; Marcelo, Adriana; Silva, Teresa Pereira; Barata, João; Vasconcelos-Ferreira, Ana; Pereira, Dina; Nóbrega, Clévio; et al, Molecular Therapy. 2131 - 2151. 9. 26. 2018. http://dx.doi.org/10.1016/j.ymthe.2018.07.007 . 10.1016/j.ymthe.2018.07.007 . Molecular Therapy
Repeated mesenchymal stromal cells treatment sustainably alleviates Machado-Joseph disease/spinocerebellar ataxia type-3
Miranda, C. O.; Marcelo, A.; Silva, T. P.; Barata, J.; Vasconcelos-Ferreira, A.; Pereira, D.; Duarte, S.; et al, Human Gene Therapy. 2018. https://publons.com/wos-op/publon/18881710/ . Human Gene Therapy
Assessing cerebellar neurometabolic biomarkers by in vivo magnetic resonance spectroscopy in a transgenic mouse model of Machado-Joseph disease
Miranda, C. O.; Nobre, R. J.; Paiva, V. H.; Castelhano, J.; Petrella, L.; Sereno, J.; Castelo-Branco, M.; Pereira de Almeida, L., Human Gene Therapy. 2018. https://publons.com/wos-op/publon/18798609/ . Human Gene Therapy
Early axonal loss accompanied by impaired endocytosis, abnormal axonal transport, and decreased microtubule stability occur in the model of Krabbe's disease
Teixeira, Carla Andreia; Miranda, Catarina Oliveira; Sousa, Vera Filipe; Santos, Telma Emanuela; Malheiro, Ana Rita; Solomon, Melani; Maegawa, Gustavo H.; Brites, Pedro; Sousa, Monica Mendes, Neurobiology of Disease. 2014. https://publons.com/publon/11055779/ . 10.1016/J.NBD2014.02.012 . Neurobiology of Disease
Advances and pitfalls of cell therapy in metabolic leukodystrophies
Miranda, C.O.; Brites, P.; Sousa, M.M.; Teixeira, C.A., Cell Transplantation. 189 - 204. 2. 22. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874371497&partnerID=MN8TOARS . 10.3727/096368912X656117 . Cell Transplantation
Primary Bone Marrow Mesenchymal Stromal Cells Rescue the Axonal Phenotype of Twitcher Mice.
Miranda CO; Teixeira CA; Sousa VF; Santos TE; Liz MA; Marques AM; Pinto-do-O P; Sousa MM, 2013. http://europepmc.org/abstract/med/23809254 . 10.3727/096368913X669752 .
Expression of stem cell markers: OCT4, KIT, ITGA6, and ITGB1 in the male germinal epithelium
Sá, Rosália; Miranda, Catarina; Carvalho, Filipa; Barros, Alberto; Sousa, Mário, Systems Biology in Reproductive Medicine. 233 - 243. 5. 59. 2013. http://dx.doi.org/10.3109/19396368.2013.804964 . 10.3109/19396368.2013.804964 . Systems Biology in Reproductive Medicine
Biomarkers Expression in Human Seminiferous Epithelium
Sá, R.; Miranda, C; Leite, C.; Malheiro, I.; Carvalho, F.; Silva, J.; Barros, A.; Sousa, M.; Miranda, C., Microscopy and Microanalysis. 15 - 16. S5. 18. 2012. http://dx.doi.org/10.1017/s1431927612012731 . 10.1017/s1431927612012731 . Microscopy and Microanalysis
Systemic Delivery of Bone Marrow-Derived Mesenchymal Stromal Cells Diminishes Neuropathology in a Mouse Model of Krabbe's Disease
Miranda, Catarina Oliveira; Teixeira, Carla Andreia; Liz, Márcia Almeida; Sousa, Vera Filipe; Franquinho, Filipa; Forte, Giancarlo; Di Nardo, Paolo; Pinto-Do-Ó, Perpétua; Sousa, Mónica Mendes, STEM CELLS. 1738 - 1751. 11. 29. 2011. http://dx.doi.org/10.1002/stem.724 . 10.1002/stem.724 . STEM CELLS
5 31 out of 31 Publications
All projects
Information of exclusive responsibility of the researcher 17-11-2024 , from platform CIÊNCIAVITAE.
2023 - 2024
Pre-clinical evaluation of the brain-targeting AAV-PHP.eB encoding cholesterol hydroxylase CYP46A1 as a therapeutic strategy for spinocerebellar ataxia type 3 – towards the understanding of the neuroprotective mechanism (50K€))
2022.04788.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Funders: Fundação para a Ciência e a Tecnologia
2023 - 2024
From bedside-to-bench biomarker discovery: on the road to a clinical trial for Machado-Joseph Disease (50K))
2022.06118.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
2023 - 2024
Direct Conversion of Astrocytes into Cerebellar Neurons as an Innovative Treatment for Spinocerebellar Ataxia Type-3 - 50K€
2022.06127.PTDC
Principal investigator
Funders: Fundação para a Ciência e a Tecnologia
2022 - 2023
Dextran-PCL-based nerve guidance conduits 3D printed for nerve regeneration (100K€))
CI22-00190
Researcher
Funders: Centro de la Fundació Caixa Castelló
2022 - 2023
(Less)PlasticBrain: Bio Replacing Plasticizers - Impact in the Human Brain Development - 20K euros
NA
Principal investigator
Funders: Banco Santander Portugal
2021/03/01 -
Are mesenchymal stromal cells’ able to alleviate blood-brain-barrier impairments in Machado- Joseph disease mice?
SUBMITTED
Principal investigator
National Ataxia Foundation
Funders: AFM-Téléthon
2021/03/01 -
Are mesenchymal stromal cells’ able to alleviate blood-brain-barrier impairments in Machado- Joseph disease mice?
SUBMITTED
Principal investigator
National Ataxia Foundation
Funders: AFM-Téléthon
2020 - 2024
From mesenchymal stromal cells to its secretome: Clarifying the mechanism of alleviation of Machado-Joseph disease
SFRH/BD/148877/2019
Supervisor
Funders: Fundação para a Ciência e a Tecnologia
2019 - 2021
MESENCHYMAL STEM CELLS FOR MACHADO-JOSEPH DISEASE THERAPY
position 6 of NT CNC 2018.01-35
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Universidade de Coimbra Centro de Neurociências e Biologia Celular
2018/07 - 2021/07
Role of microRNA deregulation in Machado-Joseph Disease: On the development of a microRNA-based therapeutic strategy
PTDC/MED-NEU/32309/2017
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2017 - 2020
BrainHealth 2020 - Detecção Precoce, Neuro-modulação e Terapias Avançadas para Neuropatologias.
CENTRO-01-0145-FEDER-000008
Researcher
Funders: Funding Agency: Centro2020 - Programa Operacional Centro 2020 (FEDER/FSE) (BrainHealth 2020 CENTRO-01-0145-FEDER-000008)
2016/01 - 2018/12
Gene repair and repression strategies to alleviate Machado-Joseph disease
Provided by PTCRIS: 138667
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2015/01 - 2017/12
CNC. IBILI
Provided by PTCRIS: 147358
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2013/02/01 - 2019
Mesenchymal Stem Cells for Machado-Joseph Disease
SFRH/BPD/87732/2012
Post-doc Fellow
Funders: Fundação para a Ciência e a Tecnologia
2012/01 - 2015/07
Dissecting the pathogenesis of Machado-Joseph disease in a new human disease model derived from induced pluripotent stem cells
Provided by PTCRIS: 116512
Research Fellow
Funders: Fundação para a Ciência e a Tecnologia
2011/02 - 2014/03
Dissecting nerve regeneration and the neuritogenic activity of TTR.
Provided by PTCRIS: 111761
Research Fellow
Funders: Fundação para a Ciência e a Tecnologia
2007/11 - 2010/10
Search for the molecular basis of transthyretin involvement in the biology of the nervous system.
grant.Provided by PTCRIS: 64437
Researcher
Funders: Fundação para a Ciência e a Tecnologia
2007 - 2011
Evaluation of Cellular Therapy in Leukodystrophies with Peripheral Nervous System Demyelination
SFRH/BD/29768/2006
PhD Student Fellow
Funders: Fundação para a Ciência e a Tecnologia
2006/10 - 2007/03
Towards the establishment of cell-based therapy for repairing cardiac-injury: characterization, purification and functional analysis of potential therapeutic-beneficial cell-subsets.
PTDC/SAU-OSM/68473/2006
Researcher
Funders: Fundação para a Ciência e a Tecnologia
5 19 out of 19 projects
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