Inês Rodrigues Lopes

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PhD Student

RNA & Infection

E-mail
irlopes@cnc.uc.pt
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Inês Rodrigues Lopes graduated in Biochemistry at the University of Coimbra in 2014 and obtained her MSc degree in Biochemistry in 2016 at the University of Porto. Currently, she is a PhD student of the PhD Programme in Experimental Biology and Biomedicine (PDBEB), at the Center for Innovative Biomedicine and Biotechnology (CIBB/CNC), University of Coimbra. Inês works in the areas of Microbiology and Cell Biology. Her studies focus on the virulence mechanisms and molecular processes operating in hosts infected with bacterial pathogens with high impact in human health, such as Staphylococcus aureus, Shigella flexneri, Salmonella Typhimurium, Escherichia coli and Group B Streptococcus. She has published 4 articles in peer-reviewed journals, mainly in the area of infectious diseases. Her PhD project intends to identify host cell factors regulating Staphylococcus aureus invasion and intracellular replication to define novel therapeutic approaches.

Publications

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Information about journal articles, updated at 17-11-2024, from platform CIÊNCIAVITAE.

Flotillin-mediated stabilization of unfolded proteins in bacterial membrane microdomains

Marta Ukleja; Lara Kricks; Gabriel Torrens; Ilaria Peschiera; Rodrigues Lopes, Inês; Marcin Krupka; Julia García-Fernández; et al, Nature Communications. 5583. 15. 2024. https://doi.org/10.1038/s41467-024-49951-1 . 10.1038/s41467-024-49951-1 . published Nature Communications

Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature

Rodrigues Lopes, Inês; Alcantara, Laura Maria ; Silva, Ricardo Jorge; Josse, Jerome ; Vega, Elena Pedrero ; Cabrerizo, Ana Marina ; Bonhomme, Melanie ; et al, Nature Communications. 7174. 13. 2022. 10.1038/s41467-022-34790-9 . published Nature Communications

Shedding light on microRNA function via microscopy-based screening

Rodrigues Lopes, Ines; Silva, Ricardo Jorge; Caramelo, Ines; Eulalio, Ana; Mano, Miguel, Methods. 55 - 64. 152. 2019. 10.1016/j.ymeth.2018.09.011 . published Methods

Functional screenings reveal different requirements for host microRNAs in Salmonella and Shigella infection

Aguilar, Carmen; Cruz, Ana Rita; Rodrigues Lopes, Ines; Maudet, Claire; Sunkavalli, Ushasree; Silva, Ricardo Jorge; Sharan, Malvika; et al, Nature Microbiology. 192 - 205. 1. 5. 2019. 10.1038/s41564-019-0614-3 . published Nature Microbiology

Stress-induced host membrane remodeling protects from infection by non-motile bacterial pathogens

Tawk, Caroline; Nigro, Giulia; Rodrigues Lopes, Ines; Aguilar, Carmen; Lisowski, Clivia; Mano, Miguel; Sansonetti, Philippe; Vogel, Jörg; Eulalio, Ana, The EMBO Journal. 23. 37. 2018. 10.15252/embj.201798529 . published The EMBO Journal

5 6 out of 6 Publications

All projects

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Information of exclusive responsibility of the researcher 17-11-2024 , from platform CIÊNCIAVITAE.

2019/01 -

Staphylococcus aureus intracellular lifestyle: phenotypical profiles and underlying molecular determinants

PD/BD/146464/2019

PhD Student Fellow

Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2018/07 - 2022/12

Large-scale identification and functional characterization of host microRNAs regulating infection by clinically relevant Staphylococcus aureus strains

POCI-01-0145-FEDER-029999

Other

Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2017/09 - 2018/12

Intracellular Staphylococcus aureus: deciphering bacterial and cellular factors involved in host cell invasion by clinically relevant strains to define new therapeutic approaches (StaphIn)

Infect-ERA/0001/2015

Research Fellow

Centro de Inovação em Biomedicina e Biotecnologia

Funders: European Commission Seventh Framework Programme for Research and Technological Development Health

2015/09 - 2016/12

Avaliação do impacto de uma nova vacina contra as doenças dos recém-nascidos causadas pelo estreptococos do grupo B na microbiota comensal

POCI-01-0145-FEDER-016607

Master Student Fellow

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar

Funders: Fundação para a Ciência e a Tecnologia; European Regional Development Fund

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