Lino Ferreira

miRNA-642a-3p protects ß cells from glucolipotoxicity

Sandra Sofia Pinhanços; João Teixeira de Oliveira; C. Henrique Alves; Cláudia M. Deus; Twan J.J. de Winter; Sofia Viana; Flávio Reis; et al, Molecular Therapy Nucleic Acids. 2025. http://dx.doi.org/10.1016/j.omtn.2025.102498 . 10.1016/j.omtn.2025.102498 . Molecular Therapy Nucleic Acids

Nanoscale piezoelectric patches preserve electrical integrity of infarcted hearts

Luís M. Monteiro; Pedro J. Gouveia; Francisco Vasques-Nóvoa; Susana Rosa; Ifigeneia Bardi; Rita N. Gomes; Simão Correia-Santos; et al, Materials Today Bio. 2025. http://dx.doi.org/10.1016/j.mtbio.2025.101742 . 10.1016/j.mtbio.2025.101742 . Materials Today Bio

Dual-targeted hyaluronic acid conjugates on lipid nanoparticles improve delivery and efficacy against glioblastoma: The linkage leads the fate

Maria Mendes; José Sereno; Maria Luísa Ramos; Ana Fortuna; Rui Oliveira; Susana Simões; Lino Ferreira; et al, International Journal of Biological Macromolecules. 2025. http://dx.doi.org/10.1016/j.ijbiomac.2025.148404 . 10.1016/j.ijbiomac.2025.148404 . International Journal of Biological Macromolecules

DREAMS: Drug REpurposing with Artificial Intelligence for Muscular Disorders

Miagoux, Quentin; Brulle-Soumare, Laura; Lemoine, Juliette; Maignan, Nicolas; Ravinder, Rubal; Khazen, Wael; Mejat, Alexandre; et al, Drug Repurposing. 2. 2. 2025. https://doi.org/10.58647/drugrepo.25.1.0006 . 10.58647/drugrepo.25.1.0006 . Drug Repurposing

Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux

Heloísa Gerardo; Tânia Lourenço; Júlio Torres; Manuela Ferreira; Célia Aveleira; Susana Simões; Lino Ferreira; et al, European Journal of Clinical Investigation. 2025. http://dx.doi.org/10.1111/eci.70051 . 10.1111/eci.70051 . European Journal of Clinical Investigation

Engineering extracellular vesicles to transiently permeabilize the blood–brain barrier

Francesca Tomatis; Susana Rosa; Susana Simões; Marta Barão; Carlos Jesus; João Novo; Emanuel Barth; Manja Marz; Lino Ferreira, Journal of Nanobiotechnology. 2024. https://doi.org/10.1186/s12951-024-03019-w . 10.1186/s12951-024-03019-w . Journal of Nanobiotechnology

POSEIDON: Peptidic Objects SEquence-based Interaction with cellular DOmaiNs: a new database and predictor

Preto, António J.; Caniceiro, Ana B.; Duarte, Francisco; Fernandes, Hugo; Ferreira, Lino; Mourão, Joana; Moreira, Irina S., Journal of Cheminformatics. 1. 16. 2024. http://dx.doi.org/10.1186/s13321-024-00810-7 . 10.1186/s13321-024-00810-7 . Journal of Cheminformatics

Cellular reprogramming as a tool to model human aging in a dish

Patricia R. Pitrez; Luis M. Monteiro; Oliver Borgogno; Xavier Nissan; Jerome Mertens; Lino Ferreira, Nature Communications. 2024. https://doi.org/10.1038/s41467-024-46004-5 . 10.1038/s41467-024-46004-5 . Nature Communications

Near-Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR-Cas9 Ribonucleoprotein for Brain Gene Editing

Simões, Susana; Lino, Miguel; Barrera, Angela; Rebelo, Catarina; Tomatis, Francesca; Vilaça, Andreia; Breunig, Christopher; et al, Angewandte Chemie International Edition. 2024. http://dx.doi.org/10.1002/anie.202401004 . 10.1002/anie.202401004 . Angewandte Chemie International Edition

Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells

Andreia Vilaça; Carlos Jesus; Miguel Lino; Danika Hayman; Costanza Emanueli; Cesare M. Terracciano; Hugo Fernandes; Leon J. de Windt; Lino Ferreira, Molecular Therapy - Nucleic Acids. 2024. https://doi.org/10.1016/j.omtn.2024.102233 . 10.1016/j.omtn.2024.102233 . Molecular Therapy - Nucleic Acids

Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule

Kelly, George; Kataura, Tetsushi; Panek, Johan; Ma, Gailing; Salmonowicz, Hanna; Davis, Ashley; Kendall, Hannah; et al, Developmental Cell. 2024. http://dx.doi.org/10.1016/j.devcel.2024.04.020 . 10.1016/j.devcel.2024.04.020 . Developmental Cell

Synthetic and biological nanoparticles for cancer immunotherapy

Inês Oliveira; Paulo Rodrigues-Santos; Lino Ferreira; Ricardo Pires das Neves, Biomaterials Science. 2024. https://doi.org/10.1039/D4BM00995A . 10.1039/D4BM00995A . Biomaterials Science

Blood–brain barrier dysfunction in aging is mediated by brain endothelial senescence

João P. Novo; Lucy Gee; Carolina A. Caetano; Inês Tomé; Andreia Vilaça; Thomas von Zglinicki; Irina S. Moreira; et al, Aging Cell. 2024. https://doi.org/10.1111/acel.14270 . 10.1111/acel.14270 . Aging Cell

ENPP1 induces blood-brain barrier dysfunction and promotes brain metastasis formation in HER2-positive breast cancer

Gomes, Célia; Tomatis, Francesca; Ferreira, Hugo R S; Almeida, Sara F F; Ciputra, Edward; Sereno, José; Almeida, Rui; et al, Neuro-Oncology. 1 - 17. 2024. http://dx.doi.org/10.1093/neuonc/noae169 . 10.1093/neuonc/noae169 . accepted Neuro-Oncology

Nanoparticle-encapsulated retinoic acid for the modulation of bone marrow hematopoietic stem cell niche

Emanuel Quartin; Susana Rosa; Sara Gonzalez-Anton; Laura Mosteo Lopez; Vitor Francisco; Delfim Duarte; Cristina Lo Celso; Ricardo Pires das Neves; Lino Ferreira, Bioactive Materials. 2024. https://doi.org/10.1016/j.bioactmat.2023.12.017 . 10.1016/j.bioactmat.2023.12.017 . Bioactive Materials

Unveiling the antitumor mechanism of 7a-acetoxy-6ß-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma

Magalhaes, Mariana; Dominguez-Martin, Eva Maria; Jorge, Joana; Goncalves, Ana Cristina; Massenzio, Francesca; Spigarelli, Renato; Ribeiro-Rodrigues, Teresa; et al, Journal of Ethnopharmacology. 2024. https://publons.com/wos-op/publon/69563706/ . 10.1016/J.JEP.2024.118689 . Journal of Ethnopharmacology

Acidic sophorolipid and antimicrobial peptide based formulation as antimicrobial and antibiofilm agents.

Seena S; Ferrão R; Pala M; Roelants SLKW; Soetaert W; Stevens CV; Ferreira L; Rai A, Biomaterials advances. 2023. https://doi.org/10.1016/j.bioadv.2023.213299 . 10.1016/j.bioadv.2023.213299 . Biomaterials advances

Engineering optical tools for remotely controlled brain stimulation and regeneration

Artur Filipe Rodrigues; Catarina Rebelo; Tiago Reis; Susana Simões; Liliana Bernardino; João Peça; Lino Ferreira, Biomaterials Science. 2023. https://doi.org/10.1039/D2BM02059A . 10.1039/D2BM02059A . Biomaterials Science

Reconsidering the role of blood-brain barrier in Alzheimer's disease: From delivery to target.

Sousa JA; Bernardes C; Bernardo-Castro S; Lino M; Albino I; Ferreira L; Brás J; et al, Frontiers in aging neuroscience. 2023. https://europepmc.org/articles/PMC9978015 . 10.3389/fnagi.2023.1102809 . Frontiers in aging neuroscience

Protein-Nanoparticle Interactions Govern the Interfacial Behavior of Polymeric Nanogels: Study of Protein Corona Formation at the Air/Water Interface.

Federico Traldi; Liu P; Inês Maria Cunha Albino; Ferreira L; Ali Zarbakhsh; Marina Resmini, International journal of molecular sciences. 2023. https://europepmc.org/articles/PMC9917661 . 10.3390/ijms24032810 . International journal of molecular sciences

Engineering graphene-based electrodes for optical neural stimulation

Artur Filipe Rodrigues; Ana P. M. Tavares; Susana Simões; Rui P. F. F. Silva; Tomás Sobrino; Bruno R. Figueiredo; Goreti Sales; Lino Ferreira, Nanoscale. 2023. https://doi.org/10.1039/D2NR05256C . 10.1039/D2NR05256C . Nanoscale

Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications

Catarina Rebelo; Tiago Reis; Joana Guedes; Cláudia Saraiva; Artur Filipe Rodrigues; Susana Simões; Liliana Bernardino; et al, Nature Communications. 2023. https://doi.org/10.1038/s41467-023-39976-3 . 10.1038/s41467-023-39976-3 . Nature Communications

Retinoic Acid-Loaded Nanoparticles Promote Neurovascular Protection in Stroke.

Marta Pereira; Alba Grayston; Miguel García-Gabilondo; Vitor Francisco; Ana Clara Cristovao; João Pedro Marto; Helena L. A. Vieira; et al, Stroke. 2023. https://doi.org/10.1161/STROKEAHA.122.041839 . 10.1161/strokeaha.122.041839 . Stroke

The evolution of blood brain barrier permeability changes after stroke, and its implications on clinical outcome: a systematic review and meta-analysis.

Sara Bernardo-Castro; João André Sousa; Martins E; Helena Donato; Nunes CA; d'Almeida OC; Miguel Castelo-Branco; et al, International journal of stroke : official journal of the International Stroke Society. 2023. https://doi.org/10.1177/17474930231166306 . 10.1177/17474930231166306 . International journal of stroke : official journal of the International Stroke Society

Small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model

Lino, Miguel M.; Rondão, Tiago; Banerjee, Arnab; Aires, Inês; Rodrigues, Magda; Reis, Tiago; Santinha, António; et al, Nanoscale. 18212 - 18217. 45. 15. 2023. http://dx.doi.org/10.1039/d3nr03861k . 10.1039/d3nr03861k . Nanoscale

Designing Cell Delivery Peptides and SARS-CoV-2-Targeting Small Interfering RNAs: A Comprehensive Bioinformatics Study with Generative Adversarial Network-Based Peptide Design and <i>In Vitro</i> Assays

González, Ricardo D.; Simões, Susana; Ferreira, Lino; Carvalho, Alexandra T. P., Molecular Pharmaceutics. 6079 - 6089. 12. 20. 2023. http://dx.doi.org/10.1021/acs.molpharmaceut.3c00444 . 10.1021/acs.molpharmaceut.3c00444 . Molecular Pharmaceutics

Roadmap on nanomedicine for the central nervous system

Ciofani, Gianni; Campisi, Marco; Mattu, Clara; Kamm, Roger D; Chiono, Valeria; Raynold, Aji Alex Moothedathu; Freitas, João S; et al, Journal of Physics: Materials. 2. 6. 2023. http://dx.doi.org/10.1088/2515-7639/acab88 . 10.1088/2515-7639/acab88 . Journal of Physics: Materials

Remodelling of the cardiac extracellular matrix proteome during chronological and pathological ageing

Santinha, Deolinda; Vilaça, Andreia; Estronca, Luís; Schüler, Svenja; Bartoli, Catherine; Sandre-Giovannoli, Annachiara De; Figueiredo, Arnaldo; et al, Molecular & Cellular Proteomics. 2023. https://hdl.handle.net/10316/112004 . https://doi.org/10.1016/j.mcpro.2023.100706 . Molecular & Cellular Proteomics

Imaging platforms to dissect the in vivo communication, biodistribution and controlled release of extracellular vesicles

Banerjee, Arnab; Lino, Miguel; Jesus, Carlos; Ribeiro, Quélia; Abrunhosa, Antero; Ferreira, Lino, Journal of Controlled Release. 549 - 563. 360. 2023. http://dx.doi.org/10.1016/j.jconrel.2023.06.039 . 10.1016/j.jconrel.2023.06.039 . Journal of Controlled Release

Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability

Santos, Liliana; Tomatis, Francesca; Ferreira, Hugo R.S.; Sereno, José Vitor Oliveira; Almeida, Sara F.F.; Ferreira, Lino; Ana Paula F. da Silva; et al, Fluids and Barriers of the CNS. S1. 20. 2023. http://dx.doi.org/10.1186/s12987-023-00417-4 . 10.1186/s12987-023-00417-4 . Fluids and Barriers of the CNS

FLEXIBLE PIEZOELECTRIC PATCHES FOR IMPROVEMENT OF HEART TISSUE ACTIVITY

Monteiro, Luis Miguel; Gouveia, Pedro J.; Rosa, Susana; Vasques-Novoa, Francisco; Gomes, Rita; Bardi, Ifigeneia; Ricotti, Leonardo; et al, Tissue Engineering Part A. 2022. https://publons.com/wos-op/publon/54503179/ . Tissue Engineering Part A

Antimicrobial peptide-based materials: opportunities and challenges

Akhilesh Rai; Rafaela Ferrão; Paulo Palma; Tatiana Patricio; Paula Parreira; Elsa Anes; Chiara Tonda-Turo; et al, Journal of Materials Chemistry B. 2022. https://doi.org/10.1039/D1TB02617H . 10.1039/D1TB02617H . Journal of Materials Chemistry B

Antimicrobial Peptide-Tether Dressing Able to Enhance Wound Healing by Tissue Contact

Akhilesh Rai; Rafaela Ferrão; Denise Marta; Andreia Vilaça; Miguel Lino; Tiago Rondão; Jian Ji; Artur Paiva; Lino Ferreira, ACS Applied Materials & Interfaces. 2022. https://doi.org/10.1021/acsami.2c06601 . 10.1021/acsami.2c06601 . ACS Applied Materials & Interfaces

Multi-parametric surface plasmon resonance-based intake quantification of label-free light-activated nanoparticles by therapeutic limbal stem cells for corneal blindness

Nano Select. 2022. http://dx.doi.org/10.1002/nano.202200027 . 10.1002/nano.202200027 . Nano Select

MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson’s disease

Molecular Therapy. 2022. http://dx.doi.org/10.1016/j.ymthe.2022.06.003 . 10.1016/j.ymthe.2022.06.003 . Molecular Therapy

A NIR-II emissive polymer AIEgen for imaging-guided photothermal elimination of bacterial infection

Biomaterials. 121579 - 121579. 286. 2022. http://dx.doi.org/10.1016/j.biomaterials.2022.121579 . 10.1016/j.biomaterials.2022.121579 . Biomaterials

Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration

Molecular Therapy - Nucleic Acids. 307 - 327. 28. 2022. http://dx.doi.org/10.1016/j.omtn.2022.03.018 . 10.1016/j.omtn.2022.03.018 . Molecular Therapy - Nucleic Acids

Unraveling the potential of endothelial progenitor cells as a treatment following ischemic stroke.

Custodia A; Ouro A; Sargento-Freitas J; Aramburu-Núñez M; Pías-Peleteiro JM; Pablo Hervella; Rosell A; et al, Frontiers in neurology. 2022. https://europepmc.org/articles/PMC9492921 . 10.3389/fneur.2022.940682 . Frontiers in neurology

Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications

Catarina Rebelo; Tiago Reis; Joana Guedes; Cláudia Saraiva; Artur Filipe Rodrigues; Susana Simões; Liliana Bernardino; et al, Nature Communications. 2022. https://doi.org/10.1038/s41467-022-31791-6 . 10.1038/s41467-022-31791-6 . Nature Communications

Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells

Molecular Therapy. 2257 - 2273. 6. 30. 2022. http://dx.doi.org/10.1016/j.ymthe.2022.03.002 . 10.1016/j.ymthe.2022.03.002 . Molecular Therapy

A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts

Artur Filipe Rodrigues; Catarina Rebelo; Susana Simões; Cristiana Paulo; Sónia Pinho; Vítor Francisco; Lino Ferreira, Advanced Science. 2022. https://doi.org/10.1002/advs.202205475 . 10.1002/advs.202205475 . Advanced Science

(Epi)transcriptomics in cardiovascular and neurological complications of COVID-19.

Jusic A; Stellos K; Ferreira L; Baker AH; Devaux Y, Journal of molecular and cellular cardiology plus. 2022. https://europepmc.org/articles/PMC9330360 . 10.1016/j.jmccpl.2022.100013 . Journal of molecular and cellular cardiology plus

Strategies and challenges for non-viral delivery of non-coding RNAs to the heart.

Vilaça A; de Windt LJ; Hugo Fernandes; Ferreira L, Trends in molecular medicine. 2022. https://doi.org/10.1016/j.molmed.2022.10.002 . 10.1016/j.molmed.2022.10.002 . Trends in molecular medicine

Induced pluripotent stem cell-derived vascular networks to screen nano–bio interactions

Estronca, Luís; Francisco, Vitor; Pitrez, Patrícia; Honório, Inês; Carvalho, Lara; Vazão, Helena; Blersch, Josephine; et al, Nanoscale Horizons. 2021. http://dx.doi.org/10.1039/d0nh00550a . 10.1039/d0nh00550a . published Nanoscale Horizons

Biomedical applications of the peptide decorated gold nanoparticles

Rai, Akhilesh; Ferreira, Lino, Critical Reviews in Biotechnology. 186 - 215. 2. 41. 2021. http://dx.doi.org/10.1080/07388551.2020.1853031 . 10.1080/07388551.2020.1853031 . Critical Reviews in Biotechnology

Revisiting gene delivery to the brain: silencing and editing

João Conniot; Sepehr Talebian; Susana Simões; Lino Ferreira; João Conde, Biomaterials Science. 1065 - 1087. 4. 9. 2021. https://doi.org/10.1039/D0BM01278E . 10.1039/D0BM01278E . Biomaterials Science

Human Extracellular-Matrix Functionalization of 3D hiPSC-Based Cardiac Tissues Improves Cardiomyocyte Maturation

Almeida, Henrique V.; Tenreiro, Miguel F.; Louro, Ana F.; Abecasis, Bernardo; Santinha, Deolinda; Calmeiro, Tomás; Fortunato, Elvira; et al, ACS Applied Bio Materials. 1888 - 1899. 2. 4. 2021. http://dx.doi.org/10.1021/acsabm.0c01490 . 10.1021/acsabm.0c01490 . ACS Applied Bio Materials

High-throughput screening of nanoparticles in drug delivery

Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira, APL Bioengineering. 2021. https://doi.org/10.1063/5.0057204 . 10.1063/5.0057204 . APL Bioengineering

Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

Rui F. Simões; Rafaela Ferrão; Margarida R. Silva; Sonia L.C. Pinho; Lino Ferreira; Paulo J. Oliveira; Teresa Cunha-Oliveira, Food and Chemical Toxicology. 111967 - 111967. 149. 2021. https://doi.org/10.1016/j.fct.2021.111967 . 10.1016/j.fct.2021.111967 . Food and Chemical Toxicology

Antimicrobial and pro-angiogenic properties of soluble and nanoparticle-immobilized LL37 peptides

Michela Comune; Akhilesh Rai; Paulo Palma; Chiara TondaTuro; Lino Ferreira, Biomaterials Science. 2021. https://doi.org/10.1039/D1BM01034D . 10.1039/D1BM01034D . Biomaterials Science

Re-Use of Caco-2 Monolayers in Permeability Assays—Validation Regarding Cell Monolayer Integrity

Pires, Cristiana L.; Praça, Catarina; Martins, Patrícia A. T.; Batista de Carvalho, Ana L. M.; Ferreira, Lino; Marques, Maria Paula M.; Moreno, Maria João, Pharmaceutics. 10. 13. 2021. http://dx.doi.org/10.3390/pharmaceutics13101563 . 10.3390/pharmaceutics13101563 . Pharmaceutics

Engineered extracellular vesicles as brain therapeutics

Lino, Miguel M.; Simões, Susana; Tomatis, Francesca; Albino, Inês; Barrera, Angela; Vivien, Denis; Sobrino, Tomas; Ferreira, Lino, Journal of Controlled Release. 472 - 485. 338. 2021. http://dx.doi.org/10.1016/j.jconrel.2021.08.037 . 10.1016/j.jconrel.2021.08.037 . Journal of Controlled Release

Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke

Bernardo-Castro, Sara; Albino, Inês; Barrera-Sandoval, Ángela María; Tomatis, Francesca; Sousa, João André; Martins, Emanuel; Simões, Susana; et al, Life. 6. 11. 2021. http://dx.doi.org/10.3390/life11060482 . 10.3390/life11060482 . Life

Exogenous loading of miRNAs into small extracellular vesicles

Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al, Journal of Extracellular Vesicles. 10. 10. 2021. http://dx.doi.org/10.1002/jev2.12111 . 10.1002/jev2.12111 . Journal of Extracellular Vesicles

Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization

Tenreiro, Miguel F.; Almeida, Henrique V.; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino; Alves, Paula M.; Serra, Margarida, Scientific Reports. 1. 11. 2021. http://dx.doi.org/10.1038/s41598-021-00226-5 . 10.1038/s41598-021-00226-5 . Scientific Reports

A Light-Triggerable Nanoparticle Library for the Controlled Release of Non-Coding RNAs

Blersch, Josephine; Francisco, Vitor; Rebelo, Catarina; Jiménez-Balsa, Adrian; Antunes, Helena; Gonzato, Carlo; Pinto, Sandra; et al, Angewandte Chemie International Edition. 1985 - 1991. 5. 59. 2020. http://dx.doi.org/10.1002/anie.201911398 . 10.1002/anie.201911398 . Angewandte Chemie International Edition

A light-triggerable formulation to control the stability of pro-angiogenic transcription factor hypoxia inducible factor-1a (HIF-1a)

Josephine Blersch; Vitor Francisco; Catarina Rebelo; Adrian Jiménez-Balsa; Helena Antunes; Sandra Pinto; Susana Simões; Akhilesh Rai; Lino Ferreira, Nanoscale. 2020. https://doi.org/10.1039/C9NR10503D . 10.1039/C9NR10503D . Nanoscale

Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.

Pitrez PR; Estronca L; Monteiro LM; Colell G; Vazão H; Santinha D; Harhouri K; et al, Nature communications. 2020. http://europepmc.org/abstract/med/32807790 . 10.1038/s41467-020-17901-2 . Nature communications

Spatially resolved analysis of FFPE tissue proteomes by quantitative mass spectrometry.

Buczak K; Kirkpatrick JM; Truckenmueller F; Santinha D; Ferreira L; Roessler S; Singer S; Beck M; Ori A, Nature protocols. 2020. http://europepmc.org/abstract/med/32737464 . 10.1038/s41596-020-0356-y . Nature protocols

Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine

Raquel Ferreira; Joseph Napoli; Tariq Enver; Liliana Bernardino; Lino Ferreira, Nature Communications. 2020. https://doi.org/10.1038/s41467-020-18042-2 . 10.1038/s41467-020-18042-2 . Nature Communications

Native and bioengineered extracellular vesicles for cardiovascular therapeutics.

de Abreu RC; Fernandes H; da Costa Martins PA; Sahoo S; Emanueli C; Ferreira L, Nature reviews. Cardiology. 2020. http://europepmc.org/abstract/med/32483304 . 10.1038/s41569-020-0389-5 . Nature reviews. Cardiology

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Bernardo-Castro, Sara; Sousa, João André; Brás, Ana; Cecília, Carla; Rodrigues, Bruno; Almendra, Luciano; Machado, Cristina; et al, Frontiers in Neurology. 11. 2020. http://dx.doi.org/10.3389/fneur.2020.594672 . 10.3389/fneur.2020.594672 . Frontiers in Neurology

A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies

Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino, Methods. 2020. http://dx.doi.org/10.1016/j.ymeth.2020.12.002 . 10.1016/j.ymeth.2020.12.002 . Methods

A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity

Ferreira, Lino, Current Protocols in Stem Cell Biology. 2019. http://dx.doi.org/10.1002/cpsc.93 . 10.1002/cpsc.93 . Current Protocols in Stem Cell Biology

A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles

Arnab Banerjee; Vitor Alves; Tiago Rondão; José Sereno; Ângela Neves; Miguel Lino; Andreia Ribeiro; Antero J. Abrunhosa; Lino S. Ferreira, Nanoscale. 13243 - 13248. 28. 11. 2019. https://doi.org/10.1039/C9NR02512J . 10.1039/C9NR02512J . Nanoscale

A light-triggerable nanoparticle library for the controlled release of non-coding RNAs.

Ferreira, Lino, Angewandte Chemie (International ed. in English). 2019. https://doi.org/10.1002/anie.201911398 . 10.1002/anie.201911398 . Angewandte Chemie (International ed. in English)

Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells.

Ferreira, Lino, Stem cell reports. 2019. https://europepmc.org/articles/PMC6829749 . 10.1016/j.stemcr.2019.08.002 . Stem cell reports

A photodynamic antibacterial spray-coating based on the host–guest immobilization of the photosensitizer methylene blue

Tian-tian Yao; Jing Wang; Yun-fan Xue; Wei-jiang Yu; Qiang Gao; Lino Ferreira; Ke-Feng Ren; Jian Ji, Journal of Materials Chemistry B. 2019. https://doi.org/10.1039/C9TB01069F . 10.1039/C9TB01069F . Journal of Materials Chemistry B

The Kinetics of Small Extracellular Vesicle Delivery Impacts Skin Tissue Regeneration

Ferreira, Lino, ACS Nano. 2019. http://dx.doi.org/10.1021/acsnano.9b00376 . 10.1021/acsnano.9b00376 . ACS Nano

What human blood-brain barrier models can tell us about BBB function and drug discovery?

Ferreira, Lino, Expert opinion on drug discovery. 2019. https://doi.org/10.1080/17460441.2019.1646722 . 10.1080/17460441.2019.1646722 . Expert opinion on drug discovery

Functional characterization of iPSC-derived arterial- and venous-like endothelial cells

Ferreira, Lino, Scientific Reports. 2019. http://dx.doi.org/10.1038/s41598-019-40417-9 . 10.1038/s41598-019-40417-9 . Scientific Reports

A near infrared light-triggerable modular formulation for the delivery of small biomolecules

Ferreira, Lino, Journal of Nanobiotechnology. 2019. http://dx.doi.org/10.1186/s12951-019-0530-y . 10.1186/s12951-019-0530-y . Journal of Nanobiotechnology

Bioprocess decision support tool for scalable manufacture of extracellular vesicles

Ferreira, Lino, Biotechnology and Bioengineering. 2019. http://dx.doi.org/10.1002/bit.26809 . 10.1002/bit.26809 . Biotechnology and Bioengineering

Spatially Confining Surface Roughness on Exponentially Growing Polyelectrolyte Multilayer Films

Ferreira, Lino, Advanced Materials Interfaces. 2019. http://dx.doi.org/10.1002/admi.201900702 . 10.1002/admi.201900702 . Advanced Materials Interfaces

Unveiling the molecular crosstalk in a human induced pluripotent stem cell-derived cardiac model

Bernardo Abecasis; Patrícia Gomes-Alves; Susana Rosa; Pedro J. Gouveia; Lino Ferreira; Margarida Serra; Paula M. Alves, Biotechnology and Bioengineering. 1245 - 1252. 5. 116. 2019. https://doi.org/10.1002/bit.26929 . 10.1002/bit.26929 . Biotechnology and Bioengineering

PET imaging and in vivo bio-distribution of small extracellular vesicles

Banerjee, Arnab; Rondao, Tiago; Sereno, Jose; Alves, Vitor; Lino, Miguel; Ribeiro, Andreia; Abrunhosa, Antero; Ferreira, Lino, European Journal of Clinical Investigation. 2019. https://publons.com/wos-op/publon/53879095/ . European Journal of Clinical Investigation

Atomistic-Level Investigation of a LL37-Conjugated Gold Nanoparticle By Well-Tempered Metadynamics

André F. Ferreira; Michela Comune; Akhilesh Rai; Lino Ferreira; Pedro N. Simões, The Journal of Physical Chemistry B. 2018. https://doi.org/10.1021/acs.jpcb.8b05717 . 10.1021/acs.jpcb.8b05717 . The Journal of Physical Chemistry B

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers

Miguel M. Lino; Susana Simões; Andreia Vilaça; Helena Antunes; Alessandra Zonari; Lino Ferreira, ACS Nano. 2018. https://doi.org/10.1021/acsnano.7b07538 . 10.1021/acsnano.7b07538 . ACS Nano

Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules

Adrián Jiménez-Balsa; Sandra Pinto; Emanuel Quartin; Miguel M. Lino; Vitor Francisco; Lino Ferreira, Bioconjugate Chemistry. 2018. https://doi.org/10.1021/acs.bioconjchem.7b00820 . 10.1021/acs.bioconjchem.7b00820 . Bioconjugate Chemistry

Substrate Topography Modulates Cell Aging on a Progeria Cell Model

Patricia R. Pitrez; Luís Estronca; Helena Vazão; Anne-Laure Egesipe; Amélie Le Corf; Claire Navarro; Nicolas Lévy; et al, ACS Biomaterials Science & Engineering. 2018. https://doi.org/10.1021/acsbiomaterials.8b00224 . 10.1021/acsbiomaterials.8b00224 . ACS Biomaterials Science & Engineering

Endothelial progenitor cells enhance blood-brain barrier permeability in subacute stroke.

Sargento-Freitas J; Aday S; Nunes C; Cordeiro M; Gouveia A; Silva F; Machado C; et al, Neurology. 2018. http://europepmc.org/abstract/med/29237797 . 10.1212/wnl.0000000000004801 . Neurology

Stem cells as vehicles and targets of nanoparticles.

Pinho S; Macedo MH; Rebelo C; Sarmento B; Ferreira L, Drug discovery today. 2018. http://europepmc.org/abstract/med/29337203 . 10.1016/j.drudis.2018.01.030 . Drug discovery today

Light-triggerable formulations for the intracellular controlled release of biomolecules.

Lino MM; Ferreira L, Drug discovery today. 2018. http://europepmc.org/abstract/med/29326080 . 10.1016/j.drudis.2018.01.019 . Drug discovery today

STROKE34 Study Protocol: A Randomized Controlled Phase IIa Trial of Intra-Arterial CD34+ Cells in Acute Ischemic Stroke

Ferreira, Lino, Frontiers in Neurology. 2018. http://dx.doi.org/10.3389/fneur.2018.00302 . 10.3389/fneur.2018.00302 . Frontiers in Neurology

A nanoformulation for the preferential accumulation in adult neurogenic niches

Ferreira, Lino, Journal of Controlled Release. 2018. http://dx.doi.org/10.1016/j.jconrel.2018.06.013 . 10.1016/j.jconrel.2018.06.013 . Journal of Controlled Release

Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

Ferreira, Lino, Cell Reports. 2018. http://dx.doi.org/10.1016/j.celrep.2018.11.032 . 10.1016/j.celrep.2018.11.032 . Cell Reports

Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation

Ferreira, Lino, Scientific Reports. 2018. http://dx.doi.org/10.1038/s41598-018-25517-2 . 10.1038/s41598-018-25517-2 . Scientific Reports

Cecropin-Melittin Functionalized Polyurethane Surfaces Prevent Staphylococcus epidermidis Adhesion without Inducing Platelet Adhesion and Activation

Ferreira, Lino, Advanced Materials Interfaces. 2018. http://dx.doi.org/10.1002/admi.201801390 . 10.1002/admi.201801390 . Advanced Materials Interfaces

Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain

Ferreira, Lino, Neuroscience Letters. 2018. http://dx.doi.org/10.1016/j.neulet.2018.02.066 . 10.1016/j.neulet.2018.02.066 . Neuroscience Letters

MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo

Ferreira, Lino, PLOS ONE. 2018. http://dx.doi.org/10.1371/journal.pone.0193609 . 10.1371/journal.pone.0193609 . PLOS ONE

Endothelial Progenitor Cells influence acute and subacute stroke hemodynamics

Ferreira, Lino, Journal of the Neurological Sciences. 2018. http://dx.doi.org/10.1016/j.jns.2017.12.028 . 10.1016/j.jns.2017.12.028 . Journal of the Neurological Sciences

Restoring heart function and electrical integrity: closing the circuit.

Monteiro LM; Vasques-Nóvoa F; Ferreira L; Pinto-do-Ó P; Nascimento DS, NPJ Regenerative medicine. 2017. http://europepmc.org/abstract/med/29302345 . 10.1038/s41536-017-0015-2 . NPJ Regenerative medicine

Erratum: Restoring heart function and electrical integrity: Closing the circuit.

Monteiro LM; Vasques-Nóvoa F; Ferreira L; Pinto-do-Ó P; Nascimento DS, NPJ Regenerative medicine. 2017. http://europepmc.org/abstract/med/29303158 . 10.1038/s41536-017-0020-5 . NPJ Regenerative medicine

Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles

Ferreira, Lino, Mediators of Inflammation. 2017. http://dx.doi.org/10.1155/2017/6742427 . 10.1155/2017/6742427 . Mediators of Inflammation

Challenging the great vascular wall: Can we envision a simple yet comprehensive therapy for stroke?

Machado-Pereira M; Santos T; Ferreira L; Bernardino L; Ferreira R, Journal of tissue engineering and regenerative medicine. 2017. http://europepmc.org/abstract/med/28182332 . 10.1002/term.2427 . Journal of tissue engineering and regenerative medicine

Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model.

Ribas J; Zhang YS; Pitrez PR; Leijten J; Miscuglio M; Rouwkema J; Dokmeci MR; et al, Small (Weinheim an der Bergstrasse, Germany). 2017. http://europepmc.org/abstract/med/28211642 . 10.1002/smll.201603737 . Small (Weinheim an der Bergstrasse, Germany)

High-throughput identification of small molecules that affect human embryonic vascular development.

Vazão H; Rosa S; Barata T; Costa R; Pitrez PR; Honório I; de Vries MR; et al, Proceedings of the National Academy of Sciences of the United States of America. 2017. http://europepmc.org/abstract/med/28348206 . 10.1073/pnas.1617451114 . Proceedings of the National Academy of Sciences of the United States of America

Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition.

Aday S; Zoldan J; Besnier M; Carreto L; Saif J; Fernandes R; Santos T; et al, Nature communications. 2017. http://europepmc.org/abstract/med/28963481 . 10.1038/s41467-017-00746-7 . Nature communications

Flexible nanofilms coated with aligned piezoelectric microfibers preserve the contractility of cardiomyocytes.

Gouveia PJ; Rosa S; Ricotti L; Abecasis B; Almeida HV; Monteiro L; Nunes J; et al, Biomaterials. 2017. http://europepmc.org/abstract/med/28622605 . 10.1016/j.biomaterials.2017.05.048 . Biomaterials

Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential.

Comune M; Rai A; Chereddy KK; Pinto S; Aday S; Ferreira AF; Zonari A; et al, Journal of controlled release : official journal of the Controlled Release Society. 2017. http://europepmc.org/abstract/med/28694030 . 10.1016/j.jconrel.2017.07.007 . Journal of controlled release : official journal of the Controlled Release Society

Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis.

Ribeiro-Rodrigues TM; Laundos TL; Pereira-Carvalho R; Batista-Almeida D; Pereira R; Coelho-Santos V; Silva AP; et al, Cardiovascular research. 2017. http://europepmc.org/abstract/med/28859292 . 10.1093/cvr/cvx118 . Cardiovascular research

Findings on the interaction of the antimicrobial peptide cecropin-melittin with a gold surface from molecular dynamics studies

Ferreira, Lino, European Biophysics Journal. 2017. http://dx.doi.org/10.1007/s00249-016-1160-z . 10.1007/s00249-016-1160-z . European Biophysics Journal

Intracellular delivery of more than one protein with spatio-temporal control

Miguel M. Lino; Susana Simões; Sónia Pinho; Lino Ferreira; Lino MM; Simões S; Pinho S; Ferreira L, Nanoscale. 18668 - 18680. 47. 9. 2017. https://doi.org/10.1039/C7NR02414B . 10.1039/C7NR02414B . Nanoscale

Restoring heart function and electrical integrity: Closing the circuit (vol 2, 9, 2017)

Monteiro, Luis Miguel; Vasques-Novoa, Francisco; Ferreira, Lino; Pinto-do-O, Perpetua; Nascimento, Diana Santos, npj Regenerative Medicine. 2017. https://publons.com/wos-op/publon/35034962/ . 10.1038/S41536-017-0020-5 . npj Regenerative Medicine

Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation

Boto, Carlos; Quartin, Emanuel; Cai, Yijun; Martín-Lorenzo, Alberto; Cenador, María Begoña García; Pinto, Sandra; Gupta, Rajeev; et al, Nature Communications. 1. 8. 2017. http://dx.doi.org/10.1038/ncomms15204 . 10.1038/ncomms15204 . Nature Communications

Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles.

Santos T; Ferreira R; Quartin E; Boto C; Saraiva C; Bragança J; Peça J; et al, Acta biomaterialia. 2017. http://europepmc.org/abstract/med/28673742 . 10.1016/j.actbio.2017.06.044 . Acta biomaterialia

Retinoic acid-loaded polymeric nanoparticles enhance vascular regulation of neural stem cell survival and differentiation after ischaemia.

Ferreira R; Fonseca MC; Santos T; Sargento-Freitas J; Tjeng R; Paiva F; Castelo-Branco M; Ferreira LS; Bernardino L, Nanoscale. 2016. http://europepmc.org/abstract/med/27025400 . 10.1039/c5nr09077f . Nanoscale

Traceable microRNA-124 loaded nanoparticles as a new promising therapeutic tool for Parkinson's disease.

Saraiva C; Ferreira L; Bernardino L, Neurogenesis (Austin, Tex.). 2016. http://europepmc.org/abstract/med/28405588 . 10.1080/23262133.2016.1256855 . Neurogenesis (Austin, Tex.)

Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.

Blondel S; Egesipe AL; Picardi P; Jaskowiak AL; Notarnicola M; Ragot J; Tournois J; et al, Cell death & disease. 2016. http://europepmc.org/abstract/med/26890144 . 10.1038/cddis.2015.374 . Cell death & disease

High-density antimicrobial peptide coating with broad activity and low cytotoxicity against human cells.

Rai A; Pinto S; Evangelista MB; Gil H; Kallip S; Ferreira MG; Ferreira L, Acta biomaterialia. 2016. http://europepmc.org/abstract/med/26821340 . 10.1016/j.actbio.2016.01.035 . Acta biomaterialia

One-step synthesis of high-density peptide-conjugated gold nanoparticles with antimicrobial efficacy in a systemic infection model.

Rai A; Pinto S; Velho TR; Ferreira AF; Moita C; Trivedi U; Evangelista M; et al, Biomaterials. 2016. http://europepmc.org/abstract/med/26866877 . 10.1016/j.biomaterials.2016.01.051 . Biomaterials

Stem Cell-Based Human Blood-Brain Barrier Models for Drug Discovery and Delivery.

Aday S; Cecchelli R; Hallier-Vanuxeem D; Dehouck MP; Ferreira L, Trends in biotechnology. 2016. http://europepmc.org/abstract/med/26838094 . 10.1016/j.tibtech.2016.01.001 . Trends in biotechnology

Cardiovascular Organ-on-a-Chip Platforms for Drug Discovery and Development

Ferreira, Lino, Applied In Vitro Toxicology. 2016. http://dx.doi.org/10.1089/aivt.2016.0002 . 10.1089/aivt.2016.0002 . Applied In Vitro Toxicology

Nanomedicine Approaches to Modulate Neural Stem Cells in Brain Repair.

Santos T; Boto C; Saraiva CM; Bernardino L; Ferreira L, Trends in biotechnology. 2016. http://europepmc.org/abstract/med/26917252 . 10.1016/j.tibtech.2016.02.003 . Trends in biotechnology

Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases.

Saraiva C; Praça C; Ferreira R; Santos T; Ferreira L; Bernardino L, Journal of controlled release : official journal of the Controlled Release Society. 2016. http://europepmc.org/abstract/med/27208862 . 10.1016/j.jconrel.2016.05.044 . Journal of controlled release : official journal of the Controlled Release Society

MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson's disease.

Saraiva C; Paiva J; Santos T; Ferreira L; Bernardino L, Journal of controlled release : official journal of the Controlled Release Society. 2016. http://europepmc.org/abstract/med/27269730 . 10.1016/j.jconrel.2016.06.005 . Journal of controlled release : official journal of the Controlled Release Society

High Antimicrobial Activity and Low Human Cell Cytotoxicity of Core-Shell Magnetic Nanoparticles Functionalized with an Antimicrobial Peptide.

Maleki H; Rai A; Pinto S; Evangelista M; Cardoso RM; Paulo C; Carvalheiro T; et al, ACS applied materials & interfaces. 2016. http://europepmc.org/abstract/med/27074633 . 10.1021/acsami.6b03355 . ACS applied materials & interfaces

Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions.

Kostic I; Fidalgo-Carvalho I; Aday S; Vazão H; Carvalheiro T; Grãos M; Duarte A; et al, Scientific reports. 2015. http://europepmc.org/abstract/med/26553339 . 10.1038/srep16406 . Scientific reports

Vascular disease modeling using induced pluripotent stem cells: focus in Hutching-Gilford progeria syndrome.

Pitrez P; Rosa SC; Almeida C; Ferreira L, 2015. http://europepmc.org/abstract/med/26474704 .

Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease.

Esteves M; Cristóvão AC; Saraiva T; Rocha SM; Baltazar G; Ferreira L; Bernardino L, 2015. http://europepmc.org/abstract/med/25798108 . 10.3389/fnagi.2015.00020 .

Development of a SMCs model from HGPS-iPS and proofs of principle.

Ferreira L, Orphanet journal of rare diseases. 2015. http://europepmc.org/abstract/PMC/PMC4652490 . 10.1186/1750-1172-10-s2-o3 . Orphanet journal of rare diseases

A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells

Cecchelli, R.; Aday, S.; Sevin, E.; Almeida, C.; Culot, M.; Dehouck, L.; Coisne, C.; et al, PLoS ONE. 6. 9. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903316132&partnerID=MN8TOARS . 10.1371/journal.pone.0099733 . PLoS ONE

Boron nitride nanotube-mediated stimulation modulates F/G-actin ratio and mechanical properties of human dermal fibroblasts

Ricotti, L.; Das Neves, R.P.; Ciofani, G.; Canale, C.; Nitti, S.; Mattoli, V.; Mazzolai, B.; Ferreira, L.; Menciassi, A., Journal of Nanoparticle Research. 2. 16. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894539117&partnerID=MN8TOARS . 10.1007/s11051-014-2247-z . Journal of Nanoparticle Research

Interaction of fullerene nanoparticles with biomembranes: From the partition in lipid membranes to effects on mitochondrial bioenergetics

Santos, S.M.; Dinis, A.M.; Peixoto, F.; Ferreira, L.; Jurado, A.S.; Videira, R.A., Toxicological Sciences. 117 - 129. 1. 138. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894311599&partnerID=MN8TOARS . 10.1093/toxsci/kft327 . Toxicological Sciences

Inflammatory modulation of stem cells by Magnetic Resonance Imaging (MRI)-detectable nanoparticles

Ferreira, Lino, RSC Adv.. 2014. http://dx.doi.org/10.1039/c4ra04041d . 10.1039/c4ra04041d . RSC Adv.

A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects

Lang, N.; Pereira, M.J.; Lee, Y.; Friehs, I.; Vasilyev, N.V.; Feins, E.N.; Ablasser, K.; et al, Science Translational Medicine. 218. 6. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892553926&partnerID=MN8TOARS . 10.1126/scitranslmed.3006557 . Science Translational Medicine

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.

Chereddy KK; Her CH; Comune M; Moia C; Lopes A; Porporato PE; Vanacker J; et al, 2014. http://europepmc.org/abstract/med/25173841 . 10.1016/j.jconrel.2014.08.016 .

Combined Surface Micropatterning and Reactive Chemistry Maximizes Tissue Adhesion with Minimal Inflammation

Pereira, M.J.N.; Sundback, C.A.; Lang, N.; Cho, W.K.; Pomerantseva, I.; Ouyang, B.; Tao, S.L.; et al, Advanced Healthcare Materials. 565 - 571. 4. 3. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84898634094&partnerID=MN8TOARS . 10.1002/adhm.201300264 . Advanced Healthcare Materials

Antifungal activity of dental resins containing amphotericin B-conjugated nanoparticles

Lino, M.M.; Paulo, C.S.O.; Vale, A.C.; Vaz, M.F.; Ferreira, L.S., Dental Materials. 10. 29. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884143064&partnerID=MN8TOARS . 10.1016/j.dental.2013.07.023 . Dental Materials

Boron Nitride Nanotube-Mediated Stimulation of Cell Co-Culture on Micro-Engineered Hydrogels

Ricotti, L.; Fujie, T.; Vazão, H.; Ciofani, G.; Marotta, R.; Brescia, R.; Filippeschi, C.; et al, PLoS ONE. 8. 8. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881503335&partnerID=MN8TOARS . 10.1371/journal.pone.0071707 . PLoS ONE

A highly tunable biocompatible and multifunctional biodegradable elastomer

Pereira, M.J.N.; Ouyang, B.; Sundback, C.A.; Lang, N.; Friehs, I.; Mureli, S.; Pomerantseva, I.; et al, Advanced Materials. 1209 - 1215. 8. 25. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84874103151&partnerID=MN8TOARS . 10.1002/adma.201203824 . Advanced Materials

Efficient pro-survival/angiogenic miRNA delivery by an MRI-detectable nanomaterial

Gomes, R.S.M.; Neves, R.P.D.; Cochlin, L.; Lima, A.; Carvalho, R.; Korpisalo, P.; Dragneva, G.; et al, ACS Nano. 3362 - 3372. 4. 7. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876588539&partnerID=MN8TOARS . 10.1021/nn400171w . ACS Nano

Differential internalization of amphotericin B - Conjugated nanoparticles in human cells and the expression of heat shock protein 70

Paulo, C.S.O.; Lino, M.M.; Matos, A.A.; Ferreira, L.S., Biomaterials. 5281 - 5293. 21. 34. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877046831&partnerID=MN8TOARS . 10.1016/j.biomaterials.2013.03.048 . Biomaterials

Histamine modulates microglia function.

Ferreira R; Santos T; Gonçalves J; Baltazar G; Ferreira L; Agasse F; Bernardino L, 2012. http://europepmc.org/abstract/med/22569158 . 10.1186/1742-2094-9-90 .

Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain

Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragancia, J.; et al, ACS Nano. 10463 - 10474. 12. 6. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871596644&partnerID=MN8TOARS . 10.1021/nn304541h . ACS Nano

Histamine stimulates neurogenesis in the rodent subventricular zone

Bernardino, L.; Eiriz, M.F.; Santos, T.; Xapelli, S.; Grade, S.; Rosa, A.I.; Cortes, L.; et al, Stem Cells. 773 - 784. 4. 30. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859512101&partnerID=MN8TOARS . 10.1002/stem.1042 . Stem Cells

VEGF-functionalized dextran has longer intracellular bioactivity than VEGF in endothelial cells

Maia, J.; Vazão, H.; Pedroso, D.C.S.; Jesus, C.S.H.; Brito, R.M.M.; Grãos, M.; Gil, M.H.; Ferreira, L., Biomacromolecules. 2906 - 2916. 9. 13. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866111153&partnerID=MN8TOARS . 10.1021/bm3009268 . Biomacromolecules

Nanomedicine boosts neurogenesis: New strategies for brain repair

Santos, T.; Maia, J.; Agasse, F.; Xapelli, S.; Ferreira, L.; Bernardino, L., Integrative Biology (United Kingdom). 973 - 981. 9. 4. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870939373&partnerID=MN8TOARS . 10.1039/c2ib20129a . Integrative Biology (United Kingdom)

Nanoparticles and surfaces presenting antifungal, antibacterial and antiviral properties

Botequim, D.; Maia, J.; Lino, M.M.F.; Lopes, L.M.F.; Simões, P.N.; Ilharco, L.M.; Ferreira, L., Langmuir. 7646 - 7656. 20. 28. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861396966&partnerID=MN8TOARS . 10.1021/la300948n . Langmuir

Proliferation and skeletal myotube formation capability of C2C12 and H9c2 cells on isotropic and anisotropic electrospun nanofibrous PHB scaffolds

Ricotti, L.; Polini, A.; Genchi, G.G.; Ciofani, G.; Iandolo, D.; Vazão, H.; Mattoli, V.; et al, Biomedical Materials. 3. 7. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860717976&partnerID=MN8TOARS . 10.1088/1748-6041/7/3/035010 . Biomedical Materials

Towards the maturation and characterization of smooth muscle cells derived from human embryonic stem cells

Vazão, H.; das Neves, R.P.; Grãos, M.; Ferreira, L., PLoS ONE. 3. 6. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952523704&partnerID=MN8TOARS . 10.1371/journal.pone.0017771 . PLoS ONE

Improved survival, vascular differentiation and wound healing potential of stem cells co-cultured with endothelial cells

Pedroso, D.C.S.; Tellechea, A.; Moura, L.; Fidalgo-Carvalho, I.; Duarte, J.; Carvalho, E.; Ferreira, L., PLoS ONE. 1. 6. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79551528768&partnerID=MN8TOARS . 10.1371/journal.pone.0016114 . PLoS ONE

Sensing the cardiac environment: Exploiting cues for regeneration

Pereira, M.J.N.; Carvalho, I.F.; Karp, J.M.; Ferreira, L.S., Journal of Cardiovascular Translational Research. 616 - 630. 5. 4. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-81855221996&partnerID=MN8TOARS . 10.1007/s12265-011-9299-6 . Journal of Cardiovascular Translational Research

Three-dimensional biomaterials for the study of human pluripotent stem cells

Kraehenbuehl, T.P.; Langer, R.; Ferreira, L.S., Nature Methods. 731 - 736. 9. 8. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052294065&partnerID=MN8TOARS . 10.1038/nmeth.1671 . Nature Methods

Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction

Kraehenbuehl, T.P.; Ferreira, L.S.; Hayward, A.M.; Nahrendorf, M.; van der Vlies, A.J.; Vasile, E.; Weissleder, R.; Langer, R.; Hubbell, J.A., Biomaterials. 1102 - 1109. 4. 32. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649446021&partnerID=MN8TOARS . 10.1016/j.biomaterials.2010.10.005 . Biomaterials

Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles

Maia, J.; Santos, T.; Aday, S.; Agasse, F.; Cortes, L.; Malva, J.O.; Bernardino, L.; Ferreira, L., ACS Nano. 97 - 106. 1. 5. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955113748&partnerID=MN8TOARS . 10.1021/nn101724r . ACS Nano

Nanoparticles for intracellular-targeted drug delivery

Paulo, C.S.O.; Pires Das Neves, R.; Ferreira, L.S., Nanotechnology. 49. 22. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-81855212480&partnerID=MN8TOARS . 10.1088/0957-4484/22/49/494002 . Nanotechnology

Antifungal nanoparticles and surfaces

Paulo, C.S.O.; Vidal, M.; Ferreira, L.S., Biomacromolecules. 2810 - 2817. 10. 11. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957868674&partnerID=MN8TOARS . 10.1021/bm100893r . Biomacromolecules

Vascular differentiation of human embryonic stem cells in bioactive hydrogel-based scaffolds.

Gerecht, S.; Ferreira, L.S.; Langer, R.; Gerecht S; Ferreira LS; Langer R, Methods in molecular biology (Clifton, N.J.). 333 - 354. 584. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-75649126900&partnerID=MN8TOARS . 10.1007/978-1-60761-369-5_18 . Methods in molecular biology (Clifton, N.J.)

Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells.

Levenberg, S.; Ferreira, L.S.; Chen-Konak, L.; Kraehenbuehl, T.P.; Langer, R., Nature protocols. 1115 - 1126. 6. 5. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956696064&partnerID=MN8TOARS . 10.1038/nprot.2010.31 . Nature protocols

Stem cell-based therapies for heart regeneration: What did the bench teach us?

Ferreira, L.; Pedroso, D.C.S.; Vazão, H.; Gomes, R.S.M., Cardiovascular and Hematological Disorders - Drug Targets. 173 - 185. 3. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78549255903&partnerID=MN8TOARS . Cardiovascular and Hematological Disorders - Drug Targets

Non-leaching surfaces capable of killing microorganisms on contact

Ferreira, L.; Zumbuehl, A., Journal of Materials Chemistry. 7796 - 7806. 42. 19. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350722395&partnerID=MN8TOARS . 10.1039/b905668h . Journal of Materials Chemistry

Nanoparticles as tools to study and control stem cells

Ferreira, L., Journal of Cellular Biochemistry. 746 - 752. 4. 108. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350435073&partnerID=MN8TOARS . 10.1002/jcb.22303 . Journal of Cellular Biochemistry

Cell-responsive hydrogel for encapsulation of vascular cells

Kraehenbuehl, T.P.; Ferreira, L.S.; Zammaretti, P.; Hubbell, J.A.; Langer, R., Biomaterials. 4318 - 4324. 26. 30. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650596617&partnerID=MN8TOARS . 10.1016/j.biomaterials.2009.04.057 . Biomaterials

New Opportunities: The Use of Nanotechnologies to Manipulate and Track Stem Cells

Ferreira, L.; Karp, J.M.; Nobre, L.; Langer, R., Cell Stem Cell. 136 - 146. 2. 3. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-48349135069&partnerID=MN8TOARS . 10.1016/j.stem.2008.07.020 . Cell Stem Cell

Human embryoid bodies containing nano- And microparticulate delivery vehicles

Ferreira, L.; Squier, T.; Park, H.; Choe, H.; Kohane, D.S.; Langer, R., Advanced Materials. 2285 - 2291. 12. 20. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-48349136691&partnerID=MN8TOARS . 10.1002/adma.200702404 . Advanced Materials

Intracellular delivery of core-shell fluorescent silica nanoparticles

Fuller, J.E.; Zugates, G.T.; Ferreira, L.S.; Ow, H.S.; Nguyen, N.N.; Wiesner, U.B.; Langer, R.S., Biomaterials. 1526 - 1532. 10. 29. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38549088954&partnerID=MN8TOARS . 10.1016/j.biomaterials.2007.11.025 . Biomaterials

A biodegradable and biocompatible gecko-inspired tissue adhesive

Mahdavi, A.; Ferreira, L.; Sundback, C.; Nichol, J.W.; Chan, E.P.; Carter, D.J.D.; Bettinger, C.J.; et al, Proceedings of the National Academy of Sciences of the United States of America. 2307 - 2312. 7. 105. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-40649128784&partnerID=MN8TOARS . 10.1073/pnas.0712117105 . Proceedings of the National Academy of Sciences of the United States of America

Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells

Ferreira, L.S.; Gerecht, S.; Fuller, J.; Shieh, H.F.; Vunjak-Novakovic, G.; Langer, R., Biomaterials. 2706 - 2717. 17. 28. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947253443&partnerID=MN8TOARS . 10.1016/j.biomaterials.2007.01.021 . Biomaterials

Antifungal hydrogels

Zumbuehl, A.; Ferreira, L.; Kuhn, D.; Astashkina, A.; Long, L.; Yeo, Y.; Iaconis, T.; et al, Proceedings of the National Academy of Sciences of the United States of America. 12994 - 12998. 32. 104. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548767010&partnerID=MN8TOARS . 10.1073/pnas.0705250104 . Proceedings of the National Academy of Sciences of the United States of America

Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle-like cells and form vascular networks in vivo

Ferreira, L.S.; Gerecht, S.; Shieh, H.F.; Watson, N.; Rupnick, M.A.; Dallabrida, S.M.; Vunjak-Novakovic, G.; Langer, R., Circulation Research. 286 - 294. 3. 101. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548335261&partnerID=MN8TOARS . 10.1161/CIRCRESAHA.107.150201 . Circulation Research

Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells

Gerecht, S.; Burdick, J.A.; Ferreira, L.S.; Townsend, S.A.; Langer, R.; Vunjak-Novakovic, G., Proceedings of the National Academy of Sciences of the United States of America. 11298 - 11303. 27. 104. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547479732&partnerID=MN8TOARS . 10.1073/pnas.0703723104 . Proceedings of the National Academy of Sciences of the United States of America

Synthesis and characterization of photocurable elastomers from poly(glycerol-co-sebacate)

Nijst, C.L.E.; Bruggeman, J.P.; Karp, J.M.; Ferreira, L.; Zumbuehl, A.; Bettinger, C.J.; Langer, R., Biomacromolecules. 3067 - 3073. 10. 8. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548988907&partnerID=MN8TOARS . 10.1021/bm070423u . Biomacromolecules

Structural analysis of dextran-based hydrogels obtained chemoenzymatically

Ferreira, L.; Figueirecio, M.M.; Gil, M.H.; Ramos, M.A., Journal of Biomedical Materials Research - Part B Applied Biomaterials. 55 - 64. 1. 77. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645418697&partnerID=MN8TOARS . 10.1002/jbm.b.30394 . Journal of Biomedical Materials Research - Part B Applied Biomaterials

Co-culture of human embryonic stem cells with murine embryonic fibroblasts on microwell-patterned substrates

Khademhosseini, A.; Ferreira, L.; Blumling III, J.; Yeh, J.; Karp, J.M.; Fukuda, J.; Langer, R., Biomaterials. 5968 - 5977. 36. 27. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748769776&partnerID=MN8TOARS . 10.1016/j.biomaterials.2006.06.035 . Biomaterials

Cultivation of human embryonic stem cells without the embryoid body step enhances osteogenesis in vitro

Karp, J.M.; Ferreira, L.S.; Khademhosseini, A.; Kwon, A.H.; Yeh, J.; Langer, R.S., Stem Cells. 835 - 843. 4. 24. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745504422&partnerID=MN8TOARS . 10.1634/stemcells.2005-0383 . Stem Cells

Synthesis and characterization of new injectable and degradable dextran-based hydrogels

Maia, J.; Ferreira, L.; Carvalho, R.; Ramos, M.A.; Gil, M.H., Polymer. 9604 - 9614. 23. 46. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844528911&partnerID=MN8TOARS . 10.1016/j.polymer.2005.07.089 . Polymer

Improving the adhesion of poly(ethylene terephthalate) fibers to poly(hydroxyethyl methacrylate) hydrogels by ozone treatment: Surface characterization and pull-out tests

Ferreira, L.; Evangelista, M.B.; Martins, M.C.L.; Granja, P.L.; Esteves, J.L.; Barbosa, M.A., Polymer. 9840 - 9850. 23. 46. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-26844540116&partnerID=MN8TOARS . 10.1016/j.polymer.2005.08.033 . Polymer

Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels

Ferreira, L.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S., Biomaterials. 4707 - 4716. 23. 26. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-14844303889&partnerID=MN8TOARS . 10.1016/j.biomaterials.2004.11.051 . Biomaterials

Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels

Ferreira, L.; Rafael, A.; Lamghari, M.; Barbosa, M.A.; Gil, M.H.; Cabrita, A.M.S.; Dordick, J.S., Journal of Biomedical Materials Research - Part A. 584 - 596. 3. 68. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1342280525&partnerID=MN8TOARS . Journal of Biomedical Materials Research - Part A

Influence of different silica derivatives in the immobilization and stabilization of a Bacillus licheniformis protease (Subtilisin Carlsberg)

Ferreira, L.; Ramos, M.A.; Dordick, J.S.; Gil, M.H., Journal of Molecular Catalysis B: Enzymatic. 189 - 199. 4-6. 21. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347297355&partnerID=MN8TOARS . 10.1016/S1381-1177(02)00223-0 . Journal of Molecular Catalysis B: Enzymatic

Enzymatic synthesis of dextran-containing hydrogels

Ferreira, L.; Gil, M.H.; Dordick, J.S.; Carvalho, R., Biomaterials. 3957 - 3967. 19. 23. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036020043&partnerID=MN8TOARS . 10.1016/S0142-9612(02)00132-1 . Biomaterials

Biocatalytic polytransesterification of inulin with divinyladipate

Ferreira, L.; Gil, M.H.; Carvalho, R.; Geraldes, C.F.G.C.; Kim, D.-Y.; Dordick, J.S., Chemistry of Materials. 4009 - 4011. 10. 14. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036799646&partnerID=MN8TOARS . 10.1021/cm020393w . Chemistry of Materials

Exquisite regioselectivity and increased transesterification activity of an immobilized Bacillus subtilis protease

Ferreira, L.; Ramos, M.A.; Gil, M.H.; Dordick, J.S., Biotechnology Progress. 986 - 993. 5. 18. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036753108&partnerID=MN8TOARS . 10.1021/bp0255457 . Biotechnology Progress

Design of a drug-delivery system based on polyacrylamide hydrogels. Evaluation of structural properties

Ferreira, Lino, Chemical educator. 2001. http://link.springer.com/article/10.1007%2Fs00897010461a . 10.1007/s00897010461a . Chemical educator

Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values

Ferreira, L.; Vidal, M.M.; Gil, M.H., International Journal of Pharmaceutics. 169 - 180. 2. 194. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033968976&partnerID=MN8TOARS . 10.1016/S0378-5173(99)00375-0 . International Journal of Pharmaceutics

Preparation and characterization of gels based on sucrose modified with glycidyl methacrylate

Ferreira, L.; Vidal, M.M.; Geraldes, C.F.G.C.; Gil, M.H., Carbohydrate Polymers. 15 - 24. 1. 41. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033908440&partnerID=MN8TOARS . 10.1016/S0144-8617(99)00064-8 . Carbohydrate Polymers