public.student_biography

Pedro R. Figueiredo has a Master in Medicinal Chemistry and a Bachelor in Chemistry, both by UMinho. He is currently a PhD student at the UCoimbra developing the project "Enzymatic Synthesis of Biodegradable Amphiphilic Polymer-drugs for Cancer Treatment" at the Rational Protein Engineering group in collaboration with CICECO - Aveiro Institute of Materials.

Publications

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Information about journal articles, updated at 01-12-2024, from platform CIÊNCIAVITAE.

Reactivity of Pseudozyma antarctica lipase B towards the Synthesis of End-capped Polycaprolactone for Drug Delivery

Pedro R. Figueiredo; Armando J.D. Silvestre; Andreia F. Sousa; Alexandra T.P. Carvalho, ChemRxiv. 2024. 10.26434/chemrxiv.14045915.v1 . submitted ChemRxiv

A Simple Protocol for the Synthesis of Perylene Bisimides from Perylene Tetracarboxylic Dianhydride

Elina Marinho; Pedro R. Figueiredo; Rui Araújo; M. Fernanda Proença, RSC Advances. 16. 14. 2024. 10.1039/d4ra01576b . RSC Advances

Insights into the Degradation of Polymer-Drug Conjugates by an Overexpressed Enzyme in Cancer Cells

Pedro R. Figueiredo; Ricardo D. González; Alexandra T. P. Carvalho, Journal of Medicinal Chemistry. 2761 - 2772. 4. 66. 2023. 10.1021/acs.jmedchem.2c01781 . Journal of Medicinal Chemistry

Antidotal effect of cyclosporine A against a-amanitin toxicity in CD-1 mice, at clinical relevant doses

Garcia, Juliana; Carvalho, Alexandra; Neves, Ricardo Pires; Malheiro, Rui; Rodrigues, Daniela F.; Pedro R. Figueiredo; Bovolini, Antonio; et al, Food and Chemical Toxicology. 2022. 10.1016/j.fct.2022.113198 . Food and Chemical Toxicology

An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration - prepared from a known folate receptor ligand

Carlos B. P. Oliveira; Sérgio R. S. Veloso; Pedro R. Figueiredo; Alexandra T. P. Carvalho; Loic Hilliou; Pereira, Renato B.; David M. Pereira; et al, Soft Matter. 2022. 10.1039/D2SM00121G . Soft Matter

Development of Enzymatic Variants for the Synthesis of Bioresorbable Polyesters

Beatriz C. Almeida; Pedro R. Figueiredo; Daniel F.A.R. Dourado; Stephanie Paul; Derek Quinn; Thomas S. Moody; Andreia F. Sousa; Armando J.D. Silvestre; Alexandra T. P. Carvalho, Organic Process Research & Development. 2022. 10.1021/acs.oprd.1c00480 . Organic Process Research & Development

Human Carboxylesterase 2 in Cocaine Metabolism

Pedro R. Figueiredo; Ricardo D. González; Alexandra T. P. Carvalho, Molecular Catalysis. 2021. 10.1016/j.mcat.2021.111938 . Molecular Catalysis

Introduction of a Glycine Linker Connecting the Heavy and Light Chains in Synthetic Cardosin B-Derived Rennet Changes the Specificity of Subpocket S3'

Pedro R. Figueiredo; Sónia F.G. Santos; Beatriz C. Almeida; Isaura Simões; Alexandra T.P. Carvalho, Journal of Physical Chemistry B. 2021. 10.1021/acs.jpcb.1c01826 . Journal of Physical Chemistry B

Transcription factor allosteric regulation through substrate coordination to zinc

Beatriz C. Almeida; Jennifer Kaczmarek; Pedro R. Figueiredo; Kristala L. Jones Prather; Alexandra T.P. Carvalho, NAR Genomics and Bioinformatics. 2021. 10.1093/nargab/lqab033 . NAR Genomics and Bioinformatics

Enzymatic Synthesis of Polyesters: a QM/MM study

Pedro R. Figueiredo; Beatriz C. Almeida; Daniel F.A.R. Dourado; Andreia F. Sousa; Armando J.D. Silvestre; Alexandra T.P. Carvalho, ChemCatChem. 2020. 10.1002/cctc.202000780 . ChemCatChem

Enzymatic Polymerization of PCL-PEG Co-polymers for Biomedical Applications

Pedro Figueiredo; Beatriz C. Almeida; Alexandra T. P. Carvalho,, Frontiers in Molecular Biosciences. 109. 6. 2019. 10.3389/fmolb.2019.00109 . Frontiers in Molecular Biosciences

PCL enzymatic hydrolysis: a mechanistic study

Beatriz C. Almeida; Pedro Figueiredo; Alexandra T.P. Carvalho, ACS Omega. 2019. 10.1021/acsomega.9b00345 . ACS Omega

Adenine Derivatives: Promising Candidates for Breast Cancer Treatment

Pedro Figueiredo; Marta Costa; Olívia Pontes; Fátima Baltazar; Fernanda Proença, European Journal of Organic Chemistry. 3943 - 3956. 29. 2018. 2018. 10.1002/ejoc.201800629 . European Journal of Organic Chemistry

All projects

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Information of exclusive responsibility of the researcher 01-12-2024 , from platform CIÊNCIAVITAE.

2023/06 - 2033/12

Enhancement of Proteins to address Health Conditions

2022.15818.CPCA.A2

Researcher

Funders: Fundacao para a Computacao Cientifica Nacional

2022/05 - 2022/10

Protein Design in Biotechnology and Health

CPCA/A1/447491/2021

Researcher

Funders: Fundacao para a Computacao Cientifica Nacional

2020/01 - 2024/01

CIBB strategic plan

UIDB/04539/2020

Research Fellow

Funders: Fundação para a Ciência e a Tecnologia

2020/01 - 2020/06

Enzymatic Synthesis of Biopolymeric Conjugates for Advanced and Targeted Therapies

CPCA/A2/4568/2020

Researcher

Fundacao para a Computacao Cientifica Nacional

Funders: Fundacao para a Computacao Cientifica Nacional

2019/12 - 2024/01

Enzymatic synthesis of biodegradable amphiphilic polymer-drugs for cancer treatment

SFRH/BD/144303/2019

PhD Student Fellow

Universidade de Coimbra; Universidade de Aveiro

Funders: Fundação para a Ciência e a Tecnologia

2018/10 - 2019/11

Rational design of a thermostable esterase for the production of high-value bioplastics for biomedical applications

MIT-EXPL/ISF/0021/2017

Research Fellow

CNC.IBILI

Funders: Fundação para a Ciência e a Tecnologia

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