Paulo Rodrigues Santos

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Paulo Rodrigues-Santos is the Head of Research and Science Communication at the Institute of Immunology, Invited Assistant Professor at the Faculty of Medicine and Director of the Immunology and Oncology Laboratory of the Center for Neuroscience and Cell Biology, University of Coimbra (Portugal). PRS developed his work on Immunogenetics under the supervision of Professor Gottfried Mauff at Institute for Medical Microbiology and Hygiene, Faculty of Medicine, University of Cologne, Germany. He worked on Transplantation Immunobiology as Head of the Functional Genomics Laboratory at the Center for Histocompatibility of the Centre (Coimbra, Portugal). PRS was Chair of the Education Committee of the European Federation for Immunogenetics (EFI), Board Member of the European Complement Network (ECN) and Vice-President of the Portuguese Society for Immunology (SPI). He is Founder and Coordinator of the Portuguese Group of Immuno-Oncology (gpI-O), a joint working group of the Portuguese Society for Oncology (SPO) and the Portuguese Society for Immunology (SPI).

Affiliation

Immunology and Oncology Laboratory

Publications

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Information about journal articles, updated at 06-05-2024, from platform CIÊNCIAVITAE.

A peripheral blood mononuclear cell-based in vitro model: A tool to explore indoleamine 2, 3-dioxygenase-1 (IDO1)

Gonçalves, Milene; Furgiuele, Alessia; Rasini, Emanuela; Legnaro, Massimiliano; Ferrari, Marco; Luini, Alessandra; Rodrigues-Santos, Paulo; et al, European Journal of Pharmacology. 968. 2024. http://dx.doi.org/10.1016/j.ejphar.2024.176420 . 10.1016/j.ejphar.2024.176420 . European Journal of Pharmacology

Natural Killer T-like Cells: Immunobiology and Role in Disease

Jani-Sofia Almeida; José Manuel Casanova; Manuel Santos-Rosa; Raquel Tarazona; Rafael Solana; Paulo Rodrigues-Santos, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24032743 . 10.3390/ijms24032743 . International Journal of Molecular Sciences

Genetic polymorphisms of Toll-like receptors in leprosy patients from Southern Brazil

Masin PS; Vicentin, HA; Elpidio, LN; Sell, AM; Visentainer, L; De Lima Neto, QA; Zacarias, JM; et al, Front Genet . 2022. https://www.frontiersin.org/articles/10.3389/fgene.2022.952219 . accepted Front Genet

Dynamics of Soluble Factors and Double-Negative T Cells Associated with Response to Renal Denervation in Resistant Hypertension Patients

Joana Delgado-Silva; Paulo Rodrigues-Santos; Jani-Sofia Almeida; Manuel Santos-Rosa; Lino Gonçalves, Journal of Personalized Medicine. 2022. https://doi.org/10.3390/jpm12030343 . 10.3390/jpm12030343 . Journal of Personalized Medicine

Tumor-Infiltrating Lymphocytes and Cancer Markers in Osteosarcoma: Influence on Patient Survival

José Manuel Casanova; Jani-Sofia Almeida; John David Reith; Luana Madalena Sousa; Ruben Fonseca; Paulo Freitas-Tavares; Manuel Santos-Rosa; Paulo Rodrigues-Santos, Cancers. 2021. https://doi.org/10.3390/cancers13236075 . 10.3390/cancers13236075 . Cancers

The Role of Natural Killer Cells in Soft Tissue Sarcoma: Prospects for Immunotherapy

Tânia Fortes-Andrade; Jani Sofia Almeida; Luana Madalena Sousa; Manuel Santos-Rosa; Paulo Freitas-Tavares; José Manuel Casanova; Paulo Rodrigues-Santos, Cancers. 3865 - 3865. 15. 13. 2021. https://doi.org/10.3390/cancers13153865 . 10.3390/cancers13153865 . Cancers

Tumor and Peripheral Immune Status in Soft Tissue Sarcoma: Implications for Immunotherapy

Luana Madalena Sousa; Jani Sofia Almeida; Tânia Fortes-Andrade; Manuel Santos-Rosa; Paulo Freitas-Tavares; José Manuel Casanova; Paulo Rodrigues-Santos, Cancers. 3885 - 3885. 15. 13. 2021. https://doi.org/10.3390/cancers13153885 . 10.3390/cancers13153885 . Cancers

Acute MDPV Binge Paradigm on Mice Emotional Behavior and Glial Signature

Mafalda Campeão; Luciana Fernandes; Inês R. Pita; Cristina Lemos; Syed F. Ali; Félix Carvalho; Paulo Rodrigues-Santos; et al, Pharmaceuticals. 2021. https://www.mdpi.com/1424-8247/14/3/271 . 10.3390/ph14030271 . Pharmaceuticals

Activated double-negative T cells (CD3+CD4-CD8-HLA-DR+) define response to renal denervation for resistant hypertension

Delgado Silva, Joana; Almeida, Jani-Sofia; Rodrigues-Santos, Paulo; Santos Rosa, Manuel; Gonçalves, Lino, Clinical Immunology. 218. 2020. http://dx.doi.org/10.1016/j.clim.2020.108521 . 10.1016/j.clim.2020.108521 . Clinical Immunology

Innate Lymphoid Cells in Human Pregnancy

Mendes, João; Areia, Ana Luísa; Rodrigues-Santos, Paulo; Santos-Rosa, Manuel; Mota-Pinto, Anabela, Frontiers in Immunology. 11. 2020. http://dx.doi.org/10.3389/fimmu.2020.551707 . 10.3389/fimmu.2020.551707 . Frontiers in Immunology

NKT-Like (CD3+CD56+) Cells in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors

Almeida, Jani-Sofia; Couceiro, Patrícia; López-Sejas, Nelson; Alves, Vera; Ružicková, Lenka; Tarazona, Raquel; Solana, Rafael; et al, Frontiers in Immunology. 10. 2019. http://dx.doi.org/10.3389/fimmu.2019.02493 . 10.3389/fimmu.2019.02493 . Frontiers in Immunology

Immune Responses after Vascular Photodynamic Therapy with Redaporfin

S. Lobo, Ana Catarina; Gomes-da-Silva, Lígia C.; Rodrigues-Santos, Paulo; Cabrita, António; Santos-Rosa, Manuel; Arnaut, Luís G., Journal of Clinical Medicine. 1. 9. 2019. http://dx.doi.org/10.3390/jcm9010104 . 10.3390/jcm9010104 . Journal of Clinical Medicine

Effect of Age on NK Cell Compartment in Chronic Myeloid Leukemia Patients Treated With Tyrosine Kinase Inhibitors

Rodrigues-Santos, Paulo; López-Sejas, Nelson; Almeida, Jani Sofia; Ruzicková, Lenka; Couceiro, Patricia; Alves, Vera; Campos, Carmen; et al, 2018. 10.3389/fimmu.2018.02587 .

MONITORING IMMUNODYNAMICS IN IMMUNE CHECKPOINT INHIBITOR THERAPY FOR STAGE IIIB/IV NON-SMALL CELL LUNG CANCER

Bento, Daniela; Almeida, Jani Sofia; Couceiro, Patricia; Alves, Vera; Santos-Rosa, Manuel; Barata, Fernando Jose; Rodrigues-Santos, Paulo; Ferreira Rodrigues Figueiredo, Ana Maria, European Respiratory Journal. 52. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000455567102331&KeyUID=WOS:000455567102331 . 10.1183/13993003.congress-2018.PA2226 . European Respiratory Journal

Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease

Miranda, Catarina Oliveira; Marcelo, Adriana; Silva, Teresa Pereira; Barata, Joao; Vasconcelos-Ferreira, Ana; Pereira, Dina; Nobrega, Clevio; et al, Molecular Therapy. 2131 - 2151. 9. 26. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000447756800008&KeyUID=WOS:000447756800008 . 10.1016/j.ymthe.2018.07.007 . Molecular Therapy

The effects of physical exercise on nonmotor symptoms and on neuroimmune RAGE network in experimental parkinsonism

Viana, Sofia D.; Pita, Ines R.; Lemos, Cristina; Rial, Daniel; Couceiro, Patricia; Rodrigues-Santos, Paulo; Caramelo, Francisco; et al, Journal of Applied Physiology. 161 - 171. 1. 123. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000409453700003&KeyUID=WOS:000409453700003 . 10.1152/japplphysiol.01120.2016 . Journal of Applied Physiology

THE ROLE OF MICRORNAS IN CHRONIC MYELOID LEUKEMIA THERAPEUTIC SELECTION

Alves, R.; Goncalves, A. C.; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Ribeiro, L.; Almeida, A. M.; Sarmento-Ribeiro, A. B., Haematologica. 438 - 438. 102. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127003201&KeyUID=WOS:000404127003201 . Haematologica

SOLUBLE AND MEMBRANE-BOUND RECEPTOR-LIGAND IMMUNE CHECKPOINTS AND CHRONIC MYELOID LEUKEMIA: CORRELATIONS WITH MOLECULAR RESPONSE AND TYROSINE KINASE INHIBITOR THERAPY

Rodrigues-Santos, P.; Almeida, J. S.; Couceiro, P.; Alves, V.; Simplicio, J. R.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M., Haematologica. 430 - 431. 102. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127003184&KeyUID=WOS:000404127003184 . Haematologica

TRANSCRIBED ULTRACONSERVED NONCODING RNAS (T-UCRS) IN CHRONIC MYELOID LEUKEMIA: EXPRESSION PROFILES ASSOCIATED WITH MOLECULAR RESPONSE TO THERAPY WITH TYROSINE KINASE INHIBITORS

Rodrigues Santos, P.; Abranches, P.; Couceiro, P.; Simplicio, J. R.; Almeida, J. S.; Alves, V.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M., Haematologica. 429 - 430. 102. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127003181&KeyUID=WOS:000404127003181 . Haematologica

GENETIC VARIABILITY OF OXIDATIVE STRESS AND DNA REPAIR GENES POTENTIAL PROGNOSTIC AND THERAPEUTIC BIOMARKERS IN CHRONIC MYELOID LEUKEMIA

Goncalves, A. C.; Alves, R.; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Pereira, A.; Ribeiro, L.; et al, Haematologica. 239 - 239. 101. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000379484600521&KeyUID=WOS:000379484600521 . Haematologica

LEUKEMIC STEM CELLS DEFINED BY DIPEPTIDIL-PEPTIDASE IV (CD26) EXPRESSION IN CD34+CD38-STEM CELLS AND TYROSINE KINASE INHIBITOR THERAPY IN CHRONIC MYELOID LEUKEMIA

Rodrigues Santos, P.; Almeida, J.; Couceiro, P.; Alves, V.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M., Haematologica. 730 - 731. 101. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000379484602601&KeyUID=WOS:000379484602601 . Haematologica

PROGRAMMED CELL DEATH PROTEIN 1 (PD-1) DOWNREGULATION ON REGULATORY T CELLS DURING TYROSINE KINASE INHIBITOR THERAPY IN CHRONIC MYELOID LEUKEMIA

Rodrigues Santos, P.; Almeida, J.; Couceiro, P.; Alves, V.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M., Haematologica. 449 - 450. 101. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000379484601469&KeyUID=WOS:000379484601469 . Haematologica

MTOR INHIBITION IN CML: A NEW THERAPEUTIC OPTION

Alves, R. S.; Goncalves, A. C.; Couceiro, P.; Rodrigues-Santos, P.; Freitas-Tavares, P.; Ribeiro, L.; Almeida, A.; Sarmento-Ribeiro, A. B., Haematologica. 735 - 736. 101. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000379484602614&KeyUID=WOS:000379484602614 . Haematologica

Can membrane progesterone receptor a on T regulatory cells explain the ensuing human labour?

Areia, A.; Vale-Pereira, S.; Alves, V.; Rodrigues-Santos, P.; Santos-Rosa, M.; Moura, P.; Mota-Pinto, A., Journal of Reproductive Immunology. 22 - 26. 113. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960429929&partnerID=MN8TOARS . 10.1016/j.jri.2015.10.002 . Journal of Reproductive Immunology

Immunomedia project: learning, lecturing and spreading Immunology

Corell, A.; Martin Alonso, C.; Zarzuela, J. C.; Sanz, L. A.; Aragon, J. C.; Sempere, J. M.; Hudrisier, D.; et al, European Journal of Immunology. 1167 - 1167. 46. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000383610402746&KeyUID=WOS:000383610402746 . European Journal of Immunology

Regulation of striatal astrocytic receptor for advanced glycation end-products variants in an early stage of experimental Parkinson's disease

Viana, S.D.; Valero, J.; Rodrigues-Santos, P.; Couceiro, P.; Silva, A.M.; Carvalho, F.; Ali, S.F.; Fontes-Ribeiro, C.A.; Pereira, F.C., Journal of Neurochemistry. 598 - 609. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84981172818&partnerID=MN8TOARS . 10.1111/jnc.13682 . Journal of Neurochemistry

Monophosphoryl Lipid-A: A Promising Tool for Alzheimer's Disease Toll

Rego, Â.; Viana, S.D.; Ribeiro, C.A.F.; Rodrigues-Santos, P.; Pereira, F.C., Journal of Alzheimer's Disease. 1189 - 1202. 4. 52. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84974530211&partnerID=MN8TOARS . 10.3233/JAD-151183 . Journal of Alzheimer's Disease

Natural killer cell-based adoptive immunotherapy eradicates and drives differentiation of chemoresistant bladder cancer stem-like cells

Ferreira-Teixeira, M.; Paiva-Oliveira, D.; Parada, B.; Alves, V.; Sousa, V.; Chijioke, O.; Münz, C.; et al, BMC Medicine. 1. 14. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84992153376&partnerID=MN8TOARS . 10.1186/s12916-016-0715-2 . BMC Medicine

Gene association with leprosy: A review of published data

Mazini, P.S.; Alves, H.V.; Reis, P.G.; Lopes, A.P.; Sell, A.M.; Santos-Rosa, M.; Visentainer, J.E.L.; Rodrigues-Santos, P., Frontiers in Immunology. JAN. 6. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958211864&partnerID=MN8TOARS . 10.3389/fimmu.2015.00658 . Frontiers in Immunology

The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation

Mendes, F.; Domingues, C.; Rodrigues-Santos, P.; Abrantes, A.M.; Gonçalves, A.C.; Estrela, J.; Encarnação, J.; et al, Biochimica et Biophysica Acta - Reviews on Cancer. 168 - 175. 2. 1865. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958206655&partnerID=MN8TOARS . 10.1016/j.bbcan.2016.02.002 . Biochimica et Biophysica Acta - Reviews on Cancer

Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination.

Fonseca NA; Rodrigues AS; Rodrigues-Santos P; Alves V; Gregório AC; Valério-Fernandes Â; Gomes-da-Silva LC; et al, 2015. http://europepmc.org/abstract/med/26283155 . 10.1016/j.biomaterials.2015.08.007 .

Does progesterone administration in preterm labor influence Treg cells?

Areia AL; Vale-Pereira S; Vaz-Ambrósio A; Alves V; Rodrigues-Santos P; Rosa MS; Moura P; Mota-Pinto A, 2015. http://europepmc.org/abstract/med/26352073 . 10.1515/jpm-2015-0134 .

Drug transporters play a key role in the complex process of Imatinib resistance in vitro.

Alves R; Fonseca AR; Gonçalves AC; Ferreira-Teixeira M; Lima J; Abrantes AM; Alves V; et al, 2015. http://europepmc.org/abstract/med/25575688 . 10.1016/j.leukres.2014.12.008 .

Membrane progesterone receptors in human regulatory T cells: a reality in pregnancy.

Areia A; Vale-Pereira S; Alves V; Rodrigues-Santos P; Moura P; Mota-Pinto A, 2015. http://europepmc.org/abstract/med/25639501 . 10.1111/1471-0528.13294 .

Functional and molecular characterization of cancer stem-like cells in bladder cancer: A potential signature for muscle-invasive tumors

Ferreira-Teixeira, M.; Parada, B.; Rodrigues-Santos, P.; Alves, V.; Ramalho, J.S.; Caramelo, F.; Sousa, V.; Reis, F.; Gomes, C.M., Oncotarget. 36185 - 36201. 34. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946866394&partnerID=MN8TOARS . 10.18632/oncotarget.5517 . Oncotarget

DYNAMIC EXPANSION AND FUNCTIONAL TUNING OF NATURAL KILLER CELLS IN CHRONIC MYELOID LEUKEMIA

Rodrigues Santos, P.; Couceiro, P.; Almeida, J.; Queiros, D.; Gomes-Silva, D.; Alves, V.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M., Haematologica. 60 - 60. 100. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361204901128&KeyUID=WOS:000361204901128 . Haematologica

EVALUATION OF SNPS ON THE TOLL-LIKE RECEPTORS, NOD-LIKE RECEPTORS AND CD14 GENE IN THE RECOGNITION AND IN AUTOPHAGIC MODULATION IN RESPONSE TO INFECTION BY MYCOBACTERIUM LEPRAE

Mazini, Priscila S.; Rodrigues-Santos, Paulo; Santos-Rosa, Manuel; Vicentin, Hugo A.; Shinzato, Andressa H.; Shinzato, Mariane H.; Sell, Ana M.; Visentainer, Jeane E. L., Human Immunology. 83 - 83. 76. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000363001300112&KeyUID=WOS:000363001300112 . 10.1016/j.humimm.2015.07.118 . Human Immunology

IMMUNE MONITORING OF THERAPEUTIC EFFICACY IN CHRONIC MYELOID LEUKEMIA

Rodrigues Santos, P.; Couceiro, P.; Almeida, J.; Diniz, A.; Alves, V.; Ruzickova, L.; Freitas-Tavares, P.; Santos-Rosa, M., Haematologica. 688 - 689. 100. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361204904282&KeyUID=WOS:000361204904282 . Haematologica

POLYMORPHISMS OF DNMTS AND FOLATE/METHIONINE METABOLISM GENES INFLUENCE DNA METHYLATION, GENETIC SUSCEPTIBILITY AND PROGNOSIS OF MYELOID NEOPLASIA PATIENTS

Goncalves, A. C.; Alves, R.; Cortesao, E.; Freitas-Tavares, P.; Carda, J. P.; Rito, L.; Couceiro, P.; et al, Haematologica. 236 - 236. 100. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361204902116&KeyUID=WOS:000361204902116 . Haematologica

AMELIORATION OF KIDNEY INFLAMMATION AND APOPTOTIC CELL DEATH IN AN ANIMAL MODEL OF TYPE 2 DIABETES

Marques, Catarina; Mega, Cristina; Goncalves, Andreia; Rodrigues-Santos, Paulo; Teixeira-Lemos, Edite; Teixeira, Frederico; Ribeiro, Carlos Fontes; Reis, Flavio; Fernandes, Rosa, Nephrology Dialysis Transplantation. 174 - 174. 29. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000338013500473&KeyUID=WOS:000338013500473 . Nephrology Dialysis Transplantation

Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers.

Sereno J; Nunes S; Rodrigues-Santos P; Vala H; Rocha-Pereira P; Fernandes J; Santos-Silva A; Teixeira F; Reis F, 2014. http://europepmc.org/abstract/med/24971338 . 10.1155/2014/576929 .

Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties.

Mega C; Vala H; Rodrigues-Santos P; Oliveira J; Teixeira F; Fernandes R; Reis F; de Lemos ET, 2014. http://europepmc.org/abstract/med/24650557 . 10.1186/1758-5996-6-42 .

Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model.

Sereno J; Rodrigues-Santos P; Vala H; Rocha-Pereira P; Alves R; Fernandes J; Santos-Silva A; et al, 2014. http://europepmc.org/abstract/med/24853130 . 10.3390/ijms15058979 .

BIOMARKERS OF TRANSITION FROM CYCLOSPORINE-INDUCED RENAL DYSFUNCTION TO NEPHROTOXICITY

Sereno, Jose; Rodrigues-Santos, Paulo; Vala, Helena; Rocha-Pereira, Petronila; Fernandes, Joao; Santos-Silva, Alice; Teixeira, Frederico; Reis, Flavio, Nephrology Dialysis Transplantation. 98 - 98. 29. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000338013500254&KeyUID=WOS:000338013500254 . Nephrology Dialysis Transplantation

Sitagliptin ameliorates kidney lesions in a rat model of type 2 diabetes due to anti-inflammatory and anti-apoptotic effects

Marques, C.; Mega, C.; Goncalves, A.; Rodrigues-Santos, P.; Vala, H.; Teixeira de Lemos, E.; Teixeira, F.; et al, Virchows Archiv. S261 - S261. 465. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000344386802018&KeyUID=WOS:000344386802018 . Virchows Archiv

Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animals.

Marques C; Mega C; Gonçalves A; Rodrigues-Santos P; Teixeira-Lemos E; Teixeira F; Fontes-Ribeiro C; Reis F; Fernandes R, 2014. http://europepmc.org/abstract/med/24817793 . 10.1155/2014/538737 .

Alterations in the peripheral blood B cell subpopulations of multidrug-resistant tuberculosis patients.

Abreu MT; Carvalheiro H; Rodrigues-Sousa T; Domingos A; Segorbe-Luis A; Rodrigues-Santos P; Souto-Carneiro MM, 2013. http://europepmc.org/abstract/med/24068613 . 10.1007/s10238-013-0258-1 .

The need for transparency and good practices in the qPCR literature

Bustin, S.A.; Benes, V.; Garson, J.; Hellemans, J.; Huggett, J.; Kubista, M.; Mueller, R.; et al, Nature Methods. 1063 - 1067. 11. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887077614&partnerID=MN8TOARS . 10.1038/nmeth.2697 . Nature Methods

Serum and renal tissue markers of nephropathy in rats under immunosuppressive therapy: Cyclosporine versus sirolimus

Sereno, J.; Parada, B.; Rodrigues-Santos, P.; Lopes, P.C.; Carvalho, E.; Vala, H.; Teixeira-Lemos, E.; et al, Transplantation Proceedings. 1149 - 1156. 3. 45. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876882818&partnerID=MN8TOARS . 10.1016/j.transproceed.2013.02.085 . Transplantation Proceedings

Different pathways and biomarkers of acute and chronic cyclosporineinduced nephrotoxicity in a rat model: focus on overexpression of mTOR and Mki67

Sereno, Jose; Rodrigues-Santos, Paulo; Vala, Helena; Parada, Belmiro; Alves, Rui; Teixeira-Lemos, Edite; Rocha-Pereira, Petronila; Teixeira, Frederico; Reis, Flavio, Portuguese Journal of Nephrology & Hypertension. 197 - 208. 3. 27. 2013. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=SCIELO&KeyUT=SCIELO:S0872-01692013000300009&KeyUID=SCIELO:S0872-01692013000300009 . Portuguese Journal of Nephrology & Hypertension

Immunosuppressive therapy optimization applied in transplantation: Renal benefits of cyclosporine dose reduction and conversion to Sirolimus in a rat model

Vala, H.; Sereno, J.; Rodrigues-Santos, P.; Parada, B.; Teixeira, F.; Reis, F., Virchows Archiv. 296 - 296. 2. 463. 2013. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000323904201254&KeyUID=WOS:000323904201254 . Virchows Archiv

ABC Expression As Additionally Marker To Monitoring Response In CML - A Preliminary Study

Alves, Raquel; Goncalves, Ana Cristina; Freitas-Tavares, Paulo; Couceiro, Patricia; Rodrigues-Santos, Paulo; Sarmento-Ribeiro, Ana Bela, Blood. 21. 122. 2013. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000331385009031&KeyUID=WOS:000331385009031 . Blood

Clinical, biochemical and molecular characterization of Cystinuria in a cohort of 12 patients

Barbosa, M.; Lopes, A.; Mota, C.; Martins, E.; Oliveira, J.; Alves, S.; de Bonis, P.; et al, Clinical Genetics. 47 - 55. 1. 81. 2012. 10.1111/j.1399-0004.2011.01638.x . Clinical Genetics

Cardiac antiapoptotic and proproliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the rat

Teixeira, M.; Rodrigues-Santos, P.; Garrido, P.; Costa, E.; Parada, B.; Sereno, J.; Alves, R.; et al, Journal of Pharmacy and Bioallied Sciences. 76 - 83. 1. 4. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856859990&partnerID=MN8TOARS . 10.4103/0975-7406.92743 . Journal of Pharmacy and Bioallied Sciences

EARLY RECOMBINANT HUMAN ERYTHROPOIETIN TREATMENT PROMOTES CARDIORENAL CYTOPROTECTION IN A RAT MODEL OF CHRONIC RENAL FAILURE

Garrido, P.; Teixeira, M.; Costa, E.; Rodrigues-Santos, P.; Parada, B.; Belo, L.; Alves, R.; et al, Nephrology Dialysis Transplantation. 143 - 143. 27. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000311494700371&KeyUID=WOS:000311494700371 . Nephrology Dialysis Transplantation

Expression of ganglioside GM1 in osteosarcoma and Alzheimer's disease and its significance in B-cell functions

Kodandaraman, G.; Carneiro, M. M.; Goncalves, M.; Casanova, J.; Alves, V.; Santana, I.; Rodrigues-Santos, P., Immunology. 710 - 711. 137. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000309189106134&KeyUID=WOS:000309189106134 . Immunology

Genotipagem do Helicobacter pylori no Carcinoma Gástrico e Gastrite Crónica

Silva, Maria Reis; Oliveira, Carla; Rodrigues-Santos, Paulo; Carvalho, Lina, Jornal Português de Gastrenterologia. 218 - 225. 5. 18. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=SCIELO&KeyUT=SCIELO:S0872-81782011000500002&KeyUID=SCIELO:S0872-81782011000500002 . Jornal Português de Gastrenterologia

Expression of Genes Encoding Extracellular Matrix Macromolecules and Metalloproteinases in Avian Tibial Dyschondroplasia

Velada, I.; Capela-Silva, F.; Reis, F.; Pires, E.; Egas, C.; Rodrigues-Santos, P.; Barros, M.T., Journal of Comparative Pathology. 174 - 186. 2-3. 145. 2011. 10.1016/j.jcpa.2010.12.008 . Journal of Comparative Pathology

EXPRESSION OF CD62L, CD27 AND CD11B DEFINE A MARKED CYTOTOXIC EFFECTOR ROLE FOR NK CELLS IN RHEUMATOID ARTHRITIS

Abreu, M.; Carvalheiro, H.; Duarte, C.; Pereira-da-Silva, J. A.; Souto-Carneiro, M.; Rodrigues-Santos, P., Annals of the Rheumatic Diseases. 70. 2011. 10.1136/ard.2010.148999.5 . Annals of the Rheumatic Diseases

Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model

Parada, B.; Reis, F.; Figueiredo, A.; Nunes, P.; Teixeira-Lemos, E.; Garrido, P.; Sereno, J.; et al, Bju International. 135 - 143. 1. 107. 2011. 10.1111/j.1464-410X.2010.09326.x . Bju International

USE OF SELECTIVE AND NON-SELECTIVE COX-2 INHIBITORS IN RAT MODEL OF BLADDER CANCER: CHANGES IN HISTOLOGICAL, IMMUNOHISTOCHEMICAL, INFLAMMATORY AND GENE EXPRESSION PROFILES

Parada, A. C.; Figueiredo, J. C.; Reis, F.; Nunes, T. C.; Antunes, E.; Campos, C. N.; Cunha, F. X.; et al, European Urology Supplements. 80 - 80. 2. 10. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288715301119&KeyUID=WOS:000288715301119 . European Urology Supplements

Expression patterns of HLA-DR+ or HLA-DR- on CD4+/CD25++/CD127low regulatory T cells in patients with allergy.

Geraldes L; Morgado J; Almeida A; Todo-Bom A; Santos P; Paiva A; Cheira C; et al, Journal of Investigational Allergology and Clinical Immunology. 201 - 209. 3. 20. 2010. http://europepmc.org/abstract/med/20635785 . Journal of Investigational Allergology and Clinical Immunology

[Gastric carcinoma and chronic gastritis: epigenetic regulation of CDH1 (E-Cadherin), CDKN2A (p16INK4A), PTGS2 (COX-2) and EGFR genes through methylation].

Silva M; Azenha D; Pereira C; Almeida A; Balseiro S; Sampaio AM; Santos P; et al, Acta Medica Portuguesa. 5 - 14. 1. 23. 2010. http://europepmc.org/abstract/med/20353702 . Acta Medica Portuguesa

Effects of sitagliptin treatment on dysmetabolism, inflammation, and oxidative stress in an animal model of type 2 diabetes (ZDF rat).

Ferreira L; Teixeira-de-Lemos E; Pinto F; Parada B; Mega C; Vala H; Pinto R; et al, 2010. http://europepmc.org/abstract/med/20652060 . 10.1155/2010/592760 .

Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure

Teixeira, A. M.; Garrido, P.; Santos, P.; Alves, R.; Parada, B.; Costa, E.; Almeida, A.; et al, Renal Failure. 1073 - 1080. 9. 32. 2010. http://europepmc.org/abstract/med/20863212 . 10.3109/0886022x.2010.509897 . Renal Failure

Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis

Raposo, B.R.; Rodrigues-Santos, P.; Carvalheiro, H.; Água-Doce, A.M.; Carvalho, L.; Pereira Da Silva, J.A.; Graça, L.; Souto-Carneiro, M.M., Arthritis and Rheumatism. 2953 - 2962. 10. 62. 2010. 10.1002/art.27729 . Arthritis and Rheumatism

Preventive but Not curative efficacy of celecoxib on bladder carcinogenesis in a rat model

Sereno, J.; Parada, B.; Reis, F.; Cunha, F.X.; Teixeira-Lemos, E.; Garrido, P.; Pinto, R.; et al, Mediators of Inflammation. 2010. 2010. 10.1155/2010/380937 . Mediators of Inflammation

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

Hollenbach JA; Meenagh A; Sleator C; Alaez C; Bengoche M; Canossi A; Contreras G; et al, 2010. http://europepmc.org/abstract/med/20331834 . 10.1111/j.1399-0039.2010.01459.x .

Genetic markers in chronic urticaria

Machado, D.; Pereira, C.; Martinho, A.; Loureiro, G.; Tavares, B.; Santos, P.; Calado, G.; et al, Allergy. 40 - 40. 65. 2010. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000329462100086&KeyUID=WOS:000329462100086 . Allergy

Frequency and functional activity of Th17, Tc17 and other T-cell subsets in Systemic Lupus Erythematosus.

Henriques A; Inês L; Couto M; Pedreiro S; Santos C; Magalhães M; Santos P; et al, 2010. http://europepmc.org/abstract/med/20553755 . 10.1016/j.cellimm.2010.05.004 .

Different patterns of gene expression of CD4+/CD25++/CD127 low regulatory T cells HLA-DR plus or HLA-DR- in allergy

Geraldes, L.; Morgado, J.; Almeida, A.; Todo-Bom, A.; Santos, P.; Paiva, A.; Chieira, C.; Pais, M., Allergy. 139 - 139. 64. 2009. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000266171500306&KeyUID=WOS:000266171500306 . Allergy

Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability.

Rodrigues CF; Urbano AM; Matoso E; Carreira I; Almeida A; Santos P; Botelho F; et al, 2009. http://europepmc.org/abstract/med/19616015 . 10.1016/j.mrfmmm.2009.07.004 .

Role of IL-12, IFN-gamma and their receptors expressed by monocytes and T cells in multiple sclerosis patients

Teles, A.; Rasteiro, C.; Almeida, A.; Balseiro, S.; Sampaio, A.; Paiva, A.; Santos, P., Tissue Antigens. 339 - 339. 4. 71. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000254629500198&KeyUID=WOS:000254629500198 . Tissue Antigens

Renal inflammation after lower limbs ischemia-reperfusion syndrome

Almeida, A.; Rodrigues, C.; Cabrita, A.; Alves, R.; Santos, P., Tissue Antigens. 344 - 344. 4. 71. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000254629500212&KeyUID=WOS:000254629500212 . Tissue Antigens

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3 beta signaling pathways and changes in protein expression

Duarte, A. I.; Santos, P.; Oliveira, C. R.; Santos, M. S.; Rego, A. C., Biochimica Et Biophysica Acta-Molecular Cell Research. 994 - 1002. 6. 1783. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252296300078&KeyUID=WOS:000252296300078 . 10.1016/j.bbamcr.2008.02.016 . Biochimica Et Biophysica Acta-Molecular Cell Research

Comprehensive immunogenetics of mycobacterial disease: polymorphism, gene expression and phenotype correlations in pulmonary tuberculosis and leprosy

Santos, P.; Balseiro, S.; Almeida, A.; Domingos, A.; Segorbe-Luis, A., Tissue Antigens. 238 - 238. 3. 72. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000258444500026&KeyUID=WOS:000258444500026 . Tissue Antigens

KIR repertoire and HLA class I ligands in hematopoietic stem cell transplantation: influence in the development of graft-versus-host disease and relapse

Santos, P.; Pinto, S.; Martinho, A.; Simoes, O.; Pais, M.; Pimentel, P.; Campilho, F., Tissue Antigens. 302 - 302. 3. 72. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000258444500190&KeyUID=WOS:000258444500190 . Tissue Antigens

High proportion of CD4+CD25high regulatory T-cells in remission or low disease activity rheumatoid arthritis

Machado, P.; Leite, R.; Paiva, A.; Santos, P.; da Silva, J., Annals of the Rheumatic Diseases. A15 - A15. 67. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253443300042&KeyUID=WOS:000253443300042 . Annals of the Rheumatic Diseases

TNF, TNFR1 and TNFR2 polymorphisms in multiple sclerosis

Gala, D.; Almeida, A.; Sampaio, A.; Balseiro, S.; Paiva, A.; Santos, P., Tissue Antigens. 463 - 463. 5. 69. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000245985000237&KeyUID=WOS:000245985000237 . Tissue Antigens

Sex hormones gene receptors expression in unilateral ureteric obstruction

Alves, R.; Almeida, A.; Santos, P.; Cabrita, A., Nephrology Dialysis Transplantation. 109 - 110. 22. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253320600305&KeyUID=WOS:000253320600305 . Nephrology Dialysis Transplantation

KIR repertoire and HLA class I ligands in hematopoietic stemcell transplantation: influence in the development of graft-versus-host disease and relapse of the primary disease after transplant

Pinto, S.; Santos, P.; Martinho, A.; Pimentel, P.; Campilho, F.; Pais, M. L., Tissue Antigens. 520 - 520. 5. 69. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000245985000387&KeyUID=WOS:000245985000387 . Tissue Antigens

Angiotensin II gene receptor expression in unilateral ureteric obstruction

Alves, R.; Almeida, A.; Santos, P.; Cabrita, A., Nephrology Dialysis Transplantation. 110 - 110. 22. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253320600307&KeyUID=WOS:000253320600307 . Nephrology Dialysis Transplantation

Vitamin D immunossupressant effect on II-10 and MCP-1 during infection

Almeida, A.; Alves, R.; Cabrita, A.; Santos, P., Tissue Antigens. 436 - 436. 5. 69. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000245985000167&KeyUID=WOS:000245985000167 . Tissue Antigens

A role for transforming growth factor-beta apoptotic signaling pathway in liver injury induced by ingestion of water contaminated with high levels of Cr(VI)

Rafael, A. L.; Almeida, A.; Santos, P.; Parreira, I.; Madeira, V. M. S.; Alves, R.; Cabrita, A. M. S.; Alpoim, M. C., Toxicology and Applied Pharmacology. 163 - 173. 2. 224. 2007. 10.1016/j.taap.2007.07.004 . Toxicology and Applied Pharmacology

A comparative study for different period of time of administration of Cr(VI) in the drinking water and its effects in liver of Wistar rats

Rafael, A.; Almeida, A.; Santos, P.; Cabrita, A. S.; Alpoim, M. C., Toxicology Letters. S216 - S216. 172. 2007. 10.1016/j.toxlet.2007.05.544 . Toxicology Letters

Early effects of sirolimus on cytokine gene expression in an experimental animal model of hydronephrosis: females precede males in downregulation

Almeida, A.; Cabrita, A.; Alves, R.; Santos, P., Tissue Antigens. 508 - 509. 6. 67. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600180&KeyUID=WOS:000237949600180 . Tissue Antigens

Toxic effects of Cr(VI) in liver after administration in the drinking water to Wistar rats

Rafael, A.; Almeida, A.; Parreira, I.; Santos, P.; Carvalho, M.; Cabrita, A. M.; Alpoim, M. C., Toxicology Letters. S202 - S202. 164. 2006. 10.1016/j.toxlet.2006.07.077 . Toxicology Letters

Selective injury to dopaminergic neurons up-regulates GDNF in substantia nigra postnatal cell cultures: Role of neuron-glia crosstalk

Saavedra, A.; Baltazar, G.; Santos, P.; Carvalho, C. M.; Duarte, E. P., Neurobiology of Disease. 533 - 542. 3. 23. 2006. 10.1016/j.nbd.2006.04.008 . Neurobiology of Disease

Cytokine gene polymorphisms in lepromatous leprosy patients from Angola

Santos, P.; Balseiro, S.; Almeida, A.; Mayunga, R.; Segorbe-Luis, A., Tissue Antigens. 545 - 545. 6. 67. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600272&KeyUID=WOS:000237949600272 . Tissue Antigens

Sirolimus and the interleukins gene expression in experimental hydronephrosis

Alves, R.; Almeida, A.; Santos, P.; Cabrita, A., Nephrology Dialysis Transplantation. 305 - 305. 21. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000239919002114&KeyUID=WOS:000239919002114 . Nephrology Dialysis Transplantation

Sirolimus and the extracellular matrix turnover in experimental hydronephrosis

Alves, R.; Almeida, A.; Santos, P.; Cabrita, A., Nephrology Dialysis Transplantation. 37 - 37. 21. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000239919000097&KeyUID=WOS:000239919000097 . Nephrology Dialysis Transplantation

Cytokine gene polymorphisms and progression of Mycobacterium tuberculosis infected individuals to pulmonary disease

Santos, P.; Balseiro, S.; Almeida, A.; Domingos, A.; Segorbe-Luis, A., Tissue Antigens. 535 - 535. 6. 67. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600245&KeyUID=WOS:000237949600245 . Tissue Antigens

Androgen receptor gene expression associated with susceptibility to renal disease progression

Almeida, A.; Cabrita, A.; Alves, R.; Santos, P., Tissue Antigens. 499 - 500. 6. 67. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600156&KeyUID=WOS:000237949600156 . Tissue Antigens

Toll-like receptors polymorphisms and Mycobacterium tuberculosis: from infection to pulmonary disease

Santos, P.; Balseiro, S.; Almeida, A.; Domingos, A.; Segorbe-Luis, A., Tissue Antigens. 527 - 528. 6. 67. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600226&KeyUID=WOS:000237949600226 . Tissue Antigens

Toll-like receptors polymorphisms in lepromatous leprosy patients from Angola

Dionisio, A. M.; Balseiro, S.; Almeida, A.; Mayunga, R.; Segorbe-Luis, A.; Santos, P., Tissue Antigens. 530 - 530. 6. 67. 2006. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000237949600232&KeyUID=WOS:000237949600232 . Tissue Antigens

Toxic effects on Wistar rat kidney of lead administrated in water

Rafael, A.; Almeida, A.; Parreira, I.; Santos, P.; Carvalho, M.; Alves, R.; Cabrita, A. M.; Alpoim, M. C., Toxicology Letters. S202 - S203. 164. 2006. 10.1016/j.toxlet.2006.07.078 . Toxicology Letters

BCR-ABL fusion gene and BCR-ABL transcript - Correlation with response to therapy in Chronic Myeloid Leukaemia

Geraldes, C.; Goncalves, A. C.; Santos, P.; Tavares, P.; Teixeira, A., Blood. 297B - 297B. 11. 106. 2005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000233426101570&KeyUID=WOS:000233426101570 . Blood

Heart proliferation and apoptosis markers in experimental lead intoxication

Rafael, A. I.; Parreira, I.; Carvalho, M. T.; Santos, P.; Alpoim, C.; Cabrita, A. M. S., Faseb Journal. A489 - A490. 4. 19. 2005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227610703335&KeyUID=WOS:000227610703335 . Faseb Journal

Liver proliferation and apoptosis markers in experimental chromium intoxication

Carvalho, M. T.; Parreira, I.; Rafael, A.; Almeida, A.; Santos, P.; Alpuim, C.; Cabrita, A. S., Faseb Journal. A311 - A311. 4. 19. 2005. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000227610702153&KeyUID=WOS:000227610702153 . Faseb Journal

Mannan-binding lectin (MBL) polymorphisms and protein levels in pulmonary tuberculosis

Santos, P.; Lopes, J.; Gomes, J. M.; Pereira, L.; Freitas, A.; Domingos, A.; Regateiro, F.; Segorbe-Luis, A., Genes and Immunity. S39 - S39. 5. 2004. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221955900155&KeyUID=WOS:000221955900155 . Genes and Immunity

IL1-beta IL-6 IL12, TNF-alpha and TNF-beta produced by peripheral blood monocytes and subsets of dendritic cells in multidrug-resistant pulmonary tuberculosis

Santos, P.; Morgado, J. M.; Pratas, R.; Figueiredo, C.; Crespo, I.; Laranjeira, P.; Freitas, A.; et al, Genes and Immunity. S73 - S73. 5. 2004. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221955900290&KeyUID=WOS:000221955900290 . Genes and Immunity

Gene expression profile of co-stimulatory receptors, chemokines and cytokines using real-time PCR analysis in multidrug-resistant tuberculosis

Santos, P.; Almeida, A.; Lopes, J.; Domingos, A.; Regateiro, F.; Segorbe-Luis, A., Genes and Immunity. S71 - S71. 5. 2004. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000221955900283&KeyUID=WOS:000221955900283 . Genes and Immunity

Mannan-binding lectin (MBL) deficiency and protection of Mycobacterium tuberculosis infected individuals from progression to pulmonary disease

Santos, P.; Lopes, J.; Gomes, J. M.; Pereira, L.; Freitas, A.; Paiva, A.; Domingos, A.; Regateiro, F.; Segorbe-Luis, A., Molecular Immunology. 208 - 208. 2-4. 40. 2003. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000184975900092&KeyUID=WOS:000184975900092 . Molecular Immunology

IL-1 alpha, IL-1 beta, IL-1R, IL-1RA, IL4-RA, IL-12, IFN-gamma, TGF-beta, TNF-alpha, IL-2, IL-4, IL-6 and IL-10 gene polymorphism in rejection and infection after liver transplantation

Santos, P.; Balseiro, S.; Ballesteros, R.; Mareco, R.; Vale-Pereira, S.; Paiva, A.; Martinho, A.; et al, Genes and Immunity. S55 - S55. 4. 2003. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000183208800216&KeyUID=WOS:000183208800216 . Genes and Immunity

Lineage-specific chimerism monitoring after allogeneic hematopoietic stem cell transplantation

Caetano, J.; Martinho, A.; Freitas, A.; Paiva, A.; Silva, I.; Simoes, O.; Santos, P.; et al, Bone Marrow Transplantation. S143 - S144. 31. 2003. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000181969200433&KeyUID=WOS:000181969200433 . Bone Marrow Transplantation

Molecular typing for HLA-G and HLA-E using ARMS-PCR

Alvarez, M.; Martinho, A.; Simoes, O.; Regateiro, F. R.; Abade, A.; Santos, P., Tissue Antigens. 80 - 80. 59. 2002. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000176311300260&KeyUID=WOS:000176311300260 . Tissue Antigens

Early onset of medullary thyroid carcinoma in a kindred with multiple endocrine neoplasia type iia associated with cutaneous lichen amyloidosis.

Lemos MC; Carrilho F; Rodrigues FJ; Santos P; Carvalheiro M; Ruas MA; Regateiro FJ, 2002. http://europepmc.org/abstract/med/11939755 .

Prevalence of spondyloarthritis in Terceira, Azores: a population based study.

Bruges-Armas J; Lima C; Peixoto MJ; Santos P; Mendonça D; da Silva BM; Herrero-Beaumont G; Calin A, 2002. http://europepmc.org/abstract/med/12006333 . 10.1136/ard.61.6.551 .

Screening for HLA class I expression variants in a Portuguese caucasoid population

Balseiro, S.; Reuter, S.; Simoes, O.; Martinho, A.; Paiva, A.; Mateus, M. R.; Solva, I.; et al, Tissue Antigens. 79 - 79. 59. 2002. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000176311300257&KeyUID=WOS:000176311300257 . Tissue Antigens

HLA-G genetic polymorphism in 57 Portuguese white families studied by PCR-RFLP and PCR-SSOP

Alvarez, M.; Santos, P.; Martinho, A.; Simoes, O.; Abade, A.; Breda-Coimbra, H., Transplantation Proceedings. 1829 - 1831. 4. 31. 1999. 10.1016/s0041-1345(99)00179-7 . Transplantation Proceedings

Functional aspects of cord blood lymphocytes response to polyclonal and allogeneic activation

Paiva, A.; Freitas, A.; Loureiro, A.; Couceiro, A.; Martinho, A.; Simoes, O.; Santos, P.; et al, Bone Marrow Transplantation. S31 - S34. 22. 1998. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000075190200014&KeyUID=WOS:000075190200014 . Bone Marrow Transplantation

Relatedness among Basques, Portuguese, Spaniards, and Algerians studied by HLA allelic frequencies and haplotypes

ArnaizVillena, A.; MartinezLaso, J.; GomezCasado, E.; DiazCampos, N.; Santos, P.; Martinho, A.; BredaCoimbra, H., Immunogenetics. 37 - 43. 1. 47. 1997. 10.1007/s002510050324 . Immunogenetics

HLA-DR/DQ-haplotypes and autoantibodies in Portuguese gestational diabetic women

Carvalheiro, M.; Martinho, A.; Humbel, R. L.; Fagulha, I.; Gomes, L.; Fagulha, A.; Paiva, S.; et al, Diabetologia. 871 - 871. 40. 1997. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997XG12300865&KeyUID=WOS:A1997XG12300865 . Diabetologia

Serum antibody reactivity to recombinant mig and whole cell antigens in Mycobacterium avium infection

Plum, G.; Brenden, M.; Santos, P.; Schwarz, E.; Wahnschaffe, U.; Mauff, G.; Pulverer, G., Zentralblatt Fur Bakteriologie-International Journal of Medical Microbiology Virology Parasitology and Infectious Diseases. 348 - 360. 2-3. 284. 1996. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UY06600020&KeyUID=WOS:A1996UY06600020 . Zentralblatt Fur Bakteriologie-International Journal of Medical Microbiology Virology Parasitology and Infectious Diseases

Distribution of HLA-DR and DQ alleles in allergic patients to Parietaria lusitanica

Martinho, A.; TodoBom, A.; Cortesao, M. J.; Leitao, T.; Pereira, C.; Santos, P.; Simoes, O.; et al, Human Immunology. P865 - P865. 1-2. 47. 1996. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UM45500865&KeyUID=WOS:A1996UM45500865 . Human Immunology

HLA-A*02 subtyping in a Portuguese population

Santos, P.; Martinho, A.; Fonseca, A. M.; Simoes, O.; Ferreira, R. V.; Mateus, M. R.; Ferreira, A. M.; et al, Human Immunology. P14 - P14. 1-2. 47. 1996. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1996UM45500017&KeyUID=WOS:A1996UM45500017 . Human Immunology

All projects

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Information of exclusive responsibility of the researcher 06-05-2024 , from platform CIÊNCIAVITAE.

2024/01/01 -

IN8COLON: Single-cell metabolic reprogramming of innate lymphoid cells in patients with colorectal cancer

NRC.LPCC/CIMAGO 2023

Universidade de Coimbra Faculdade de Medicina

Funders: Liga Portuguesa Contra o Cancro Núcleo Regional do Centro

2023 - 2025

LUCA-IMMUNEXT: Immunogenomic profiles associated with therapy with immune checkpoint inhibitors in stages IIIb and IV of non-small cell lung cancer

LUCA-IMMUNEXT

Principal investigator

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Grupo de Estudos do Cancro do Pulmão (GECP)

2023 - 2025

Deciphering the role of Piezo1 mechanosensitive channel in microglia-mediated glaucomatous neurodegeneration

2022.01354.PTDC

Researcher

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2023 - 2025

The Hippo Ndr kinases roles in inflammation and neovascularization in diabetic retinopathy

2022.06170.PTDC

Researcher

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2023 - 2025

IN8COLON: Single-cell metabolic reprogramming of Innate Lymphoid Cells in Colorectal Carcinoma patients

NRC.LPCC/CIMAGO/IN8COLON

Co-Principal Investigator (Co-PI)

Funders: Liga Portuguesa Contra o Cancro

2022 - 2025

Epi-UNCOV - Unravelling how unconventional T cells are regulated by micronutrients and its role in epithelial malignancy

2022.06145.PTDC

Researcher

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação para a Ciência e a Tecnologia

2022 - 2025

Kinder-GUT - Role of diet-derived retinoids in CD8aa intraepithelial lymphocytes and intestinal defence at early-life

HR22-00754

Researcher

Universidade de Coimbra

Funders: Fundació Caixa d' Estalvis de Catalunya

2022 - 2025

COMP-S: Cultivating Compassionate Schools: The effects of an evidence-based compassionate mind training program for teachers on psychophysiological and epigenetic correlates of wellbeing, prosociality and stress

PT/FB/BL-2022-074

Researcher

Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia; Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia

Funders: Fundação Bial

2021 - 2024

Helicobacter pylori eradication therapy in Portugal: prospective, randomized, blind and multicentre trial on the efficacy of quadruple therapies and their clinical impact and immunological, oral and gut microbiota changes

PTDC/MEC-GAS/7361/2020

Researcher

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2019 -

MirAE: Immunological side effects of treatment with “checkpoint inhibitors” – immunological phenotypes and biomarkers

PEPITA2019/BST/FMUC/MirAE

Researcher

Universidade de Coimbra - Faculdade de Medicina

Funders: Banco Santander Portugal

2018/07/26 - 2022/07/25

Exercício físico e depressão: efeito antidepressivo dos exersomas

PTDC/SAU-DES/30786/2017

Researcher

Universidade de Coimbra; Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2018/02/01 - 2022/01/31

IMMUNYON: Immune Monitoring of Trabectedin (Yondelis®) Therapy In Refractory Soft Tissue Sarcoma Patients

IMMUNYON-CIMAGO12/18

Principal investigator

Associação de Apoio ao Centro de Investigação em Meio Ambiente Genética e Oncobiologia

Funders: PharmaMar SA

2017/04/01 - 2019/06/30

Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions

ProSafe/0001/2016

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2014/01/01 - 2015/12/31

STEPPING ON THE RAGE NETWORK: PHYSICAL EXERCISE IN THE MANAGEMENT OF PARKINSON´S DISEASE

EXPL/DTP-DES/0104/2013

Researcher

CNC.IBILI

Funders: Fundação para a Ciência e a Tecnologia

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2011/01/03 - 2014/07/01

CROSS-TALK BETWEEN CHRONIC RENAL FAILURE, INFLAMMATION AND ERYTHROPOIESIS IN RESISTANCE TO RECOMBINANT HUMAN ERYTHROPOIETIN THERAPY

PTDC/SAU-TOX/114253/2009

Researcher

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2005/01/01 - 2008/09/30

INFLUENCE OF TRANSPLANT PRESERVATION SOLUTIONS IN CARDIAC METABOLIC AND IMMUNOLOGICAL PROFILES

POCI/SAU-OBS/55802/2004

Researcher

Universidade de Coimbra Faculdade de Ciencias e Tecnologia

Funders: Fundação para a Ciência e a Tecnologia

2005/09 - 2008/08

NEO-NEUROGENESIS AND MICROGLIA IN TEMPORAL LOBE EPILESY: ROLE OF PRO-INFLAMMATORY CYTOKINES AND NEUROPEPTIDE Y IN NEUROPROTECTION OF NEW NEURONS

POCI/SAU-NEU/58492/2004

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2003/01 - 2008/01

Cr(VI)-INDUCED GENOTOXIC STRESS: THE SIGNALLING MECHANISMS THAT LINK CELL CYCLE AND CELL FATE

POCTI/CBO/48631/2002

Researcher

Fundação para a Ciência e a Tecnologia

Funders: Universidade de Coimbra

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