Publications
Information about journal articles, updated at 30-03-2025, from platform CIÊNCIAVITAE.
Mitochondria dysfunction induced by decyl-TPP mitochondriotropic antioxidant based on caffeic acid AntiOxCIN6 sensitizes cisplatin lung anticancer therapy due to a remodeling of energy metabolism
Amorim, Ricardo; Magalhães, Carina C.; Benfeito, Sofia; Cagide, Fernando; Tavares, Ludgero C.; Santos, Katia; Sardão, Vilma A.; et al, Biochemical Pharmacology. 219. 2024. http://dx.doi.org/10.1016/j.bcp.2023.115953 . 10.1016/j.bcp.2023.115953 . Biochemical Pharmacology
From Non-Alcoholic Fatty Liver to Hepatocellular Carcinoma: A Story of (Mal)Adapted Mitochondria
Amorim, Ricardo; Magalhães, Carina C.; Borges, Fernanda; Oliveira, Paulo J.; Teixeira, José, Biology. 4. 12. 2023. http://dx.doi.org/10.3390/biology12040595 . 10.3390/biology12040595 . Biology
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease.
Marta Afonso; Islam T; Magusto J; Amorim R; Lenoir V; F Simões R; Teixeira J; et al, Hepatology (Baltimore, Md.). 2022. https://doi.org/10.1002/hep.32756 . 10.1002/hep.32756 . Hepatology (Baltimore, Md.)
Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems
Ricardo Amorim; Inês C.M. Simões; José Teixeira; Fernando Cagide; Yaiza Potes; Pedro Soares; Adriana Carvalho; et al, Redox Biology. 102400 - 102400. 55. 2022. http://dx.doi.org/10.1016/j.redox.2022.102400 . 10.1016/j.redox.2022.102400 . Redox Biology
Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage
Amorim, Ricardo; Cagide, Fernando; Tavares, Ludgero C.; Simões, Rui F.; Soares, Pedro; Benfeito, Sofia; Baldeiras, Inês; et al, Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine
Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells
Amorim, Ricardo; Simões, Inês C. M.; Veloso, Caroline; Carvalho, Adriana; Simões, Rui F.; Pereira, Francisco B.; Thiel, Theresa; et al, Nutrients. 5. 13. 2021. http://dx.doi.org/10.3390/nu13051723 . 10.3390/nu13051723 . Nutrients
The Alterations of Mitochondrial Function during NAFLD Progression An Independent Effect of Mitochondrial ROS Production
Simões, Inês C. M.; Amorim, Ricardo; Teixeira, José; Karkucinska-Wieckowska, Agnieszka; Carvalho, Adriana; Pereira, Susana P.; Simões, Rui F.; et al, International Journal of Molecular Sciences. 13. 22. 2021. http://dx.doi.org/10.3390/ijms22136848 . 10.3390/ijms22136848 . International Journal of Molecular Sciences
Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts
Teixeira, José; Basit, Farhan; Willems, Peter H.G.M.; Wagenaars, Jori A.; van de Westerlo, Els; Amorim, Ricardo; Cagide, Fernando; et al, Free Radical Biology and Medicine. 314 - 324. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.023 . 10.1016/j.freeradbiomed.2020.12.023 . Free Radical Biology and Medicine
Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents
Catarina Oliveira; Donatella Bagetta; Fernando Cagide; José Teixeira; Ricardo Amorim; Tiago Silva; Jorge Garrido; et al, European Journal of Medicinal Chemistry. 116 - 129. 174. 2019. https://doi.org/10.1016/j.ejmech.2019.04.026 . 10.1016/j.ejmech.2019.04.026 . European Journal of Medicinal Chemistry
Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction
Benfeito, S.; Oliveira, C.; Fernandes, C.; Cagide, F.; Teixeira, J.; Amorim, R.; Garrido, J.; et al, European Journal of Medicinal Chemistry. 525 - 545. 167. 2019. http://dx.doi.org/10.1016/j.ejmech.2019.01.055 . 10.1016/j.ejmech.2019.01.055 . European Journal of Medicinal Chemistry
Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative
Teixeira, José; Amorim, Ricardo; Santos, Katia; Soares, Pedro; Datta, Sandipan; Cortopassi, Gino A.; Serafim, Teresa L.; et al, Toxicology. 123 - 139. 393. 2018. http://dx.doi.org/10.1016/j.tox.2017.11.014 . 10.1016/j.tox.2017.11.014 . Toxicology
Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid
José Teixeira; Catarina Oliveira; Fernando Cagide; Ricardo Amorim; Jorge Garrido; Fernanda Borges; Paulo J. Oliveira, Journal of Enzyme Inhibition and Medicinal Chemistry. 567 - 576. 1. 33. 2018. https://doi.org/10.1080%2F14756366.2018.1442831 . 10.1080/14756366.2018.1442831 . Journal of Enzyme Inhibition and Medicinal Chemistry
Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors
Catarina Oliveira; Fernando Cagide; José Teixeira; Ricardo Amorim; Lisa Sequeira; Francesco Mesiti; Tiago Silva; et al, Frontiers in Chemistry. 6. 2018. https://doi.org/10.3389%2Ffchem.2018.00126 . 10.3389/fchem.2018.00126 . Frontiers in Chemistry
Desrisking the Cytotoxicity of a Mitochondriotropic Antioxidant Based on Caffeic Acid by a PEGylated Strategy
Carlos Fernandes; Sofia Benfeito; Ricardo Amorim; José Teixeira; Paulo J. Oliveira; Fernando Remião; Fernanda Borges, Bioconjugate Chemistry. 2723 - 2733. 8. 29. 2018. https://doi.org/10.1021%2Facs.bioconjchem.8b00383 . 10.1021/acs.bioconjchem.8b00383 . Bioconjugate Chemistry
Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria
Teixeira, José; Oliveira, Catarina; Amorim, Ricardo; Cagide, Fernando; Garrido, Jorge; Ribeiro, José A.; Pereira, Carlos M.; et al, Scientific Reports. 1. 7. 2017. http://dx.doi.org/10.1038/s41598-017-07272-y . 10.1038/s41598-017-07272-y . Scientific Reports
Decreasing the toxicity of paraquat through the complexation with sodium salicylate: Stoichiometric analysis
Gales, Luís; Amorim, Ricardo; Afonso, Carlos Manuel M.; Carvalho, Félix; Dinis-Oliveira, Ricardo Jorge, Toxicology. 96 - 98. 336. 2015. http://dx.doi.org/10.1016/j.tox.2015.08.005 . 10.1016/j.tox.2015.08.005 . Toxicology
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