Publications
Information about journal articles, updated at 23-03-2025, from platform CIÊNCIAVITAE.
Do sperm need to sleep? An overview on the impact of sleep disturbances on male (in)fertility
Cristo, Maria I.; Carvalhas-Almeida, Catarina; Cavadas, Claudia; Ramalho-Santos, João; Amaral, Sandra; Álvaro, Ana Rita , Sleep medicine reviews. 2025. 10.1016/j.smrv.2025.102080 . 10.1016/j.smrv.2025.102080 . accepted Sleep medicine reviews
Prevalence and impact of antisperm antibodies in semen quality and male reproductive health aspects: a 10-year retrospective study. DOI: 10.1111/andr.70020
Silva, Andreia; Amaral, Sandra; Ramalho-Santos, João; Schlatt, S.; Schubert, Maria; Kliesch, Sabine, Fertility and Sterility. 2025. DOI: 10.1111/andr.70020 . DOI: 10.1111/andr.70020 . in press Fertility and Sterility
New insights on sperm function in male infertility of unknown origin: a multimodal approach
Pacheco, Rita; Cristo, Maria I., Biomolecules . 10. 13. 2023. https://doi.org/10.3390/biom13101462 . Biomolecules 2023, 13(10), 1462; https://doi.org/10.3390/biom13101462 . published Biomolecules
Why some couples can not have children
Amaral, Sandra; Escada-Rebelo, S.; Cristo, Maria I.; Ramalho-Santos, João; Varela Amaral, Sara; Silva, Andreia, Frontiers for young minds. 1107336. 11. 2023. doi: 10.3389/frym.2023.1107336 . published Frontiers for young minds
Metabolic characterization of human sperm cells using the Seahorse metabolic flux analyzer
Freitas-Martins, Artur; Cristo, Maria I.; Sousa, Maria Inês; Ramalho-Santos, João; Amaral, Sandra, Andrology . 2023. DOI:10.1111/andr.13486 . published Andrology
MITOCHONDRIA-TARGETED COMPOUNDS TO ASSESS AND IMPROVE HUMAN SPERM FUNCTION
Escada-Rebelo, Sara; Cristo, Maria Inês; Ramalho-Santos, Joao; Amaral, Sandra, Antioxidants & Redox Signaling. 2021. http://dx.doi.org/10.1089/ars.2021.0238 . 10.1089/ars.2021.0238 . published Antioxidants & Redox Signaling
The impact of antisperm antibodies on human male reproductive function: an update
Silva, Andreia Filipa; Ramalho-Santos, João; Amaral, Sandra, Reproduction. R55 - R71. 4. 162. 2021. http://dx.doi.org/10.1530/rep-21-0123 . 10.1530/rep-21-0123 . published Reproduction
Can Antidiabetic Drugs Improve Male Reproductive (Dys)Function Associated with Diabetes?
Tavares, Renata S.; Escada-Rebelo, Sara; Sousa, Maria Inês; Silva, Andreia; Ramalho-Santos, João; Amaral, Sandra, Current Medicinal Chemistry. 4191 - 4222. 22. 26. 2019. http://dx.doi.org/10.2174/0929867325666181101111404 . 10.2174/0929867325666181101111404 . published Current Medicinal Chemistry
Raman micro-spectroscopy analysis of different sperm regions: a species comparison
Amaral, Sandra; Da Costa, Raul; Wübbeling, Frank; Redmann, Klaus; Schlatt, S, MHR: Basic science of reproductive medicine. 185 - 202. 4. 24. 2018. http://dx.doi.org/10.1093/molehr/gax071 . 10.1093/molehr/gax071 . published MHR: Basic science of reproductive medicine
Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?
Silva, Andreia; Escada-Rebelo, S.; Amaral, Sandra; Tavares, Renata S.; Schlatt, S; Ramalho-Santos, João; Mota, Paula C, PLoS ONE. 2. 13. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041519878&partnerID=MN8TOARS . 10.1371/journal.pone.0191912 . published PLoS ONE
Spectral features of nuclear DNA in human sperm assessed by Raman Microspectroscopy: Effects of UV-irradiation and hydration
da Costa, Raul; Amaral, Sandra; Redmann, Klaus; Kliesch, S; Schlatt, S., PloS one. e0207786 - e0207786. 11. 13. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85056802974&partnerID=MN8TOARS . 10.1371/journal.pone.0207786 . published PloS one
Antidiabetic therapies and male reproductive function: where do we stand? (top dowloaded paper in 2018 on Reproduction Journal)
Tavares, Renata S.; Escada-Rebelo, Sara; Silva, Andreia; Sousa, Maria Inês; Ramalho-Santos, João; Amaral, Sandra, Reproduction (Cambridge, England). R13 - R37. 1. 155. 2017. http://europepmc.org/abstract/med/28993453 . 10.1530/rep-17-0390 . published Reproduction (Cambridge, England)
High glucose levels affect spermatogenesis: an in vitro approach.
Tavares, Renata S.; Portela, J; Sousa, Maria Inês; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, Reproduction, Fertility and Development. 1369 - 1378. 7. 29. 2017. http://europepmc.org/abstract/med/27264729 . 10.1071/rd15475 . published Reproduction, Fertility and Development
Mitochondrial Functionality and Chemical Compound Action on Sperm Function
Amaral, Sandra; Tavares, Renata S.; Baptista, Marta; Sousa, Maria Inês; Silva, Andreia; Escada-Rebelo, Sara; Paiva, Carla; Ramalho-Santos, João, Current Medicinal Chemistry. 3575 - 3606. 31. 23. 2016. http://dx.doi.org/10.2174/0929867323666160425113518 . 10.2174/0929867323666160425113518 . published Current Medicinal Chemistry
Spermatogonial stem cell organization in felid testis as revealed by Dolichos biflorus lectin.
Escada-Rebelo, Sara; Silva, Andreia; Amaral, Sandra; Tavares, Renata S.; Paiva, Carla; Schlatt, S; Ramalho-Santos, João; Mota, Paula C, Andrology. 1159 - 1168. 6. 4. 2016. http://europepmc.org/abstract/med/27317258 . 10.1111/andr.12223 . published Andrology
In vitro exposure to the organochlorine p,p'-DDE affects functional human sperm parameters
Tavares, Renata S.; Amaral, Sandra; Paiva, Carla; Baptista, Marta; Ramalho-Santos, João, Chemosphere. 443 - 446. 120. 2015. http://dx.doi.org/10.1016/j.chemosphere.2014.08.075 . 10.1016/j.chemosphere.2014.08.075 . published Chemosphere
High glucose concentrations per se do not adversely affect human sperm function in vitro
Portela, Joana; Tavares, Renata S.; Mota, Paula C; Ramalho-Santos, João; Amaral, Sandra, REPRODUCTION. 77 - 84. 1. 150. 2015. http://dx.doi.org/10.1530/rep-15-0100 . 10.1530/rep-15-0100 . published REPRODUCTION
Concentration-dependent Sildenafil citrate (Viagra) effects on ROS production, energy status, and human sperm function
Sousa, Maria Inês; Amaral, Sandra; Tavares, Renata S.; Paiva, Carla; Ramalho-Santos, João, Systems Biology in Reproductive Medicine. 72 - 79. 2. 60. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901672805&partnerID=MN8TOARS . 10.3109/19396368.2013.867380 . published Systems Biology in Reproductive Medicine
Mitochondria and mammalian reproduction
Ramalho-Santos, João; Amaral, Sandra, Molecular and Cellular Endocrinology. 74 - 84. 1-2. 379. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884535027&partnerID=MN8TOARS . 10.1016/j.mce.2013.06.005 . published Molecular and Cellular Endocrinology
Aging and male reproductive function: a mitochondrial perspective.
Amaral, Sandra; Ramalho-Santos, João, 181 - 187. S5. 2013. http://europepmc.org/abstract/med/23277044 . 10.2741/s365 . published
UVB irradiation as a tool to assess ROS-induced damage in human spermatozoa
Amaral, Sandra; Redmann, Klaus; Sanchez, V.; Mallidis, Con; Ramalho-Santos, João; Schlatt, S, Andrology. 707 - 714. 5. 1. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883044268&partnerID=MN8TOARS . 10.1111/j.2047-2927.2013.00098.x . published Andrology
Aging, Mitochondria and Male Reproductive Function
Amaral, Sandra; Ramalho-Santos, João, Current Aging Sciencee. 165 - 173. 3. 2. 2009. http://dx.doi.org/10.2174/1874609810902030165 . 10.2174/1874609810902030165 . published Current Aging Sciencee
Mitochondrial functionality in reproduction: from gonads and gametes to embryos and embryonic stem cells
Ramalho-Santos, João; Varum, Sandra; Amaral, Sandra; Mota, Paula C; Ana Paula Sousa; Amaral, Alexandra, Human Reproduction Update. 553 - 572. 5. 15. 2009. http://dx.doi.org/10.1093/humupd/dmp016 . 10.1093/humupd/dmp016 . published Human Reproduction Update
Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)- A model for endangered species
Mota, Paula C; Amaral, Sandra; Martins, Luís; de Lourdes Pereira, Maria; Oliveira, Paulo; Ramalho-Santos, João, Reproductive Toxicology. 111 - 116. 2. 27. 2009. http://dx.doi.org/10.1016/j.reprotox.2009.01.008 . 10.1016/j.reprotox.2009.01.008 . published Reproductive Toxicology
Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic rats
Amaral, Sandra; Mota, Paula C; Lacerda, Beatriz; Alves, Marco; Pereira, Maria de Lourdes; Oliveira, Paulo; Ramalho-Santos, João, Mitochondrion. 41 - 50. 1. 9. 2009. http://dx.doi.org/10.1016/j.mito.2008.11.005 . 10.1016/j.mito.2008.11.005 . published Mitochondrion
Diabetes and the Impairment of Reproductive Function: Possible Role of Mitochondria and Reactive Oxygen Species
Ramalho-Santos, João; Amaral, Sandra; Oliveira, Paulo, Current Diabetes Reviews. 46 - 54. 1. 4. 2008. http://dx.doi.org/10.2174/157339908783502398 . 10.2174/157339908783502398 . published Current Diabetes Reviews
Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leak
Amaral, Sandra; Mota, Paula C; Rodrigues, Ana Sofia; Martins, Luís; Oliveira, Paulo; Ramalho-Santos, João, FEBS Letters. 4191 - 4196. 30. 582. 2008. http://dx.doi.org/10.1016/j.febslet.2008.11.020 . 10.1016/j.febslet.2008.11.020 . published FEBS Letters
Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetes
Amaral, Sandra; Moreno, António J.; Santos, Maria Sancha; Seiça, Raquel; Ramalho-Santos, João, Theriogenology. 2056 - 2067. 9. 66. 2006. http://dx.doi.org/10.1016/j.theriogenology.2006.06.006 . 10.1016/j.theriogenology.2006.06.006 . published Theriogenology
5 28 out of 28 Publications
All projects
Information of exclusive responsibility of the researcher 23-03-2025 , from platform CIÊNCIAVITAE.
2021 - 2025
SR&TD Project - SCHL 394/16-1 " Biochemical and physiological characterization of human spermatozoa using novel optical technologies - A new understanding of sperm functional competence" (400k|3yrs| DGF)
SCHL 394/16-1
Researcher
Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie
Funders: Deutsche Forschungsgemeinschaft
2018 - 2022
SR&TD Project - PTDC/MEC-AND/28599/2017 |(POCI-01-0145-FEDER-028599) (236.679,81 eur, 3 Years, FCT): "Searching for novel biomarkers in unknown origin (UOMI) male infertility"
PTDC/MEC-AND/28599/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2016/01 - 2017/12
Cooperation Project- AI A06/16 (4000 eur, 2 Years, CRUP_DAAD) : "Pesquisa de novos biomarcadores para a infertilidade masculina inexplicada"
AI06/ 16
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie
Funders: Deutscher Akademischer Austauschdienst; CRUP (Conselho de Reitores das Universidades Portuguesas-Portuguese Council of University Rectors)
2013 - 2015
Cooperation project: Bilateral exchanging program between FCT and DAAD. "Fertility preservation in endangered felids"
n/a
Researcher
Universitätsklinikum Münster Centrum für Reproduktionsmedizin und Andrologie
Funders: Deutscher Akademischer Austauschdienst; Fundação para a Ciencia e Tecnologia
2013/01 - 2014/12
Exploratory project - EXPL/BEX-BCM/0224/2012 (48.132 eur, 1.5 year, FCT):"Novel insights into the reproductive dysfunction in diabetes: 3D dimensional analysis of spermatogenesis and analysis of mitochondria status through Confocal Raman Microscopy"
EXPL/BEX-BCM/0224/2012
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciencia e Tecnologia
2012 - 2015
PTDC/EBB-EBI/120634/2010 "Metabolic modulation as a tool to create and propagate pluripotent stem cell lines"
PTDC/EBB-EBI/120634/2010
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2015
PTDC/QUI-BIQ/120652/2010 "Role of the pyruvate dehydrogenase Kinase metabolic swith in pluripotency insights into cancer and stem cell biology"
PTDC/QUI-BIQ/120652/2010
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2015
PTDC/CVT/119477/2010:"New strategies to recover fertility and genetic variability of endangered felids: development of xenografting and spermatogonial stem cell transplantation in domestic cat as model for endangered felids"
PTDC/CVT/119477/2010
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2010 - 2013
PTDC/EBB-EBI/101114/2008 " Metabolism as a modulator of stem cell pluripotency and differentiation"
PTDC/EBB-EBI/101114/2008
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2006 - 2008
III/BIO/50/2005 "What makes a good spermatozoon? a trans-specific perspective" University of coimbra, Instituto de investigação interdisciplinar
III/BIO/50/2005
Other
Universidade de Coimbra
Funders: Universidade de Coimbra
5 10 out of 10 projects
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