Overview

We found that maternal nutrition during pregnancy can adversely impact fetal renal, hepatic and cardiac mitochondrial biology. Now we are investigating whether fetal mitochondrial energy metabolism can be modulated during gestation by other factors to improve fetal health and decrease diseases incidence.

Affiliation

CNC - Center for Neuroscience and Cell Biology, University of Coimbra

Publications

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Information about journal articles, updated at 18-04-2024, from platform CIÊNCIAVITAE.

Characterizing Early Cardiac Metabolic Programming via 30% Maternal Nutrient Reduction during Fetal Development in a Non-Human Primate Model

Susana P. Pereira; Mariana S. Diniz; Ludgero C. Tavares; Teresa Cunha-Oliveira; Cun Li; Laura A. Cox; Mark J. Nijland; Peter W. Nathanielsz; Paulo J. Oliveira, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms242015192 . 10.3390/ijms242015192 . International Journal of Molecular Sciences

Maternal hepatic adaptations during obese pregnancy encompass lobe-specific mitochondrial alterations and oxidative stress.

Grilo, Luís F.; João D. Martins; Diniz, Mariana S.; Chiara H. Cavallaro; Tocantins, Carolina; Baldeiras, Inês; Cunha-Oliveira, Teresa; et al, Clinical Sciences. 2023. accepted Clinical Sciences

Metabolic mitochondrial alterations prevail in the female rat heart 8 weeks after exercise cessation.

Tocantins, Carolina; João D. Martins; Óscar M. Rodrigues; Grilo, Luís F.; Diniz, Mariana S.; Jelena Stevanovic-Silva; Beleza, Jorge; et al, European Journal of Clinical Investigation . e14069. 2023. http://dx.doi.org/10.1111/eci.14069 . 10.1111/eci.14069 . published European Journal of Clinical Investigation

Fetoplacental endothelial dysfunction in gestational diabetes mellitus and maternal obesity: A potential threat for programming cardiovascular disease

Diniz, Mariana S.; Hiden, Ursula; Falcão-Pires, Inês; Oliveira, Paulo J.; Sobrevia Luis ; Susana P. Pereira, Biochimica et Biophysica Acta: Molecular Basis of Disease . 166834. 2023. https://doi.org/10.1016/j.bbadis.2023.166834 . 10.1016/j.bbadis.2023.166834 . in press Biochimica et Biophysica Acta: Molecular Basis of Disease

Maternal obesity and reduced maternal nutrition during fetal development differentially result in altered cardiac transcriptome regulating cardiomyocyte maturation, proliferation, and enlargement at late gestation.

Luís F. Grilo; Susana P. Pereira; Oliveira, Paulo J.; Cun Li; Kenneth Lange; Jeremy P. Glenn ; Kip D. Zimmerman ; Nathanielsz, Peter W.; Cox, Laura A., Cellular and Molecular Life Sciences . 2023. submitted Cellular and Molecular Life Sciences

Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models

Diana Sousa; Mariana Rocha; Andreia Marreiros Amaro; Marcos Divino Ferreira-Junior; Keilah Valéria Naves Cavalcante; Tamaeh Monteiro-Alfredo; Tamaeh Monteiro Alfredo; Cátia Barra; et al, Nutrients. 5. 15. 2023. https://www.mdpi.com/2072-6643/15/5/1281 . 10.3390/nu15051281 . published Nutrients

Made in the Womb: Maternal Programming of Offspring Cardiovascular Function by an Obesogenic Womb

Diniz, Mariana S.; Grilo, Luís F.; Tocantins, Carolina; Falcão-Pires, Inês; Susana P. Pereira, Metabolites. 7. 13. 2023. https://doi.org/10.3390/metabo13070845 . 10.3390/metabo13070845 . published Metabolites

Nurturing through Nutrition: Exploring the Role of Antioxidants in Maternal Diet during Pregnancy to Mitigate Developmental Programming of Chronic Diseases

Mariana S. Diniz; Carina C. Magalhães; Carolina Tocantins; Luís F. Grilo; José Teixeira; Susana P. Pereira, Nutrients. 2023. https://doi.org/10.3390/nu15214623 . 10.3390/nu15214623 . Nutrients

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Shift in the Left Ventricle Promoting Cardiac Remodelling Through Stimulation of the Hexosaminase Biosynthetic Pathway and Glycosaminoglycans Accumulation.

Grilo, Luís F.; Kip D. Zimmerman ; Sobha Puppala; Jeannie Chan; Isaac Ampong; Hillary F. Huber; Ge Li; et al, 2023. submitted

The Bitter Side of Sugar Consumption: A Mitochondrial Perspective on Diabetes Development

Mariana S. Diniz; Carolina Tocantins; Luis F. Grilo; Pereira SP, Diabetology. 2022. https://susy.mdpi.com/user/manuscripts/review_info/b82370c44de6e15f27ed2e711c9e17a0 . 10.3390/diabetology3040044 . Diabetology

Mitochondria-targeted phenolic acid derivative AntiOxCIN4 prevented hepatic lipid accumulation by increasing fatty acid oxidation and antioxidant defense systems regulating quality control mechanism in a NAFLD model

Ricardo Amorim; Inês C. M. Simões; José Teixeira; Yaiza Potes; Pedro Soares; Adriana Carvalho; Ludgero Tavares; et al, 2022. submitted

Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems

Ricardo Amorim; Inês C.M. Simões; José Teixeira; Fernando Cagide; Yaiza Potes; Pedro Soares; Adriana Carvalho; et al, Redox Biology. 102400 - 102400. 55. 2022. http://dx.doi.org/10.1016/j.redox.2022.102400 . 10.1016/j.redox.2022.102400 . Redox Biology

The Endocrine–Metabolic Axis Regulation in Offspring Exposed to Maternal Obesity—Cause or Consequence in Metabolic Disease Programming?

Luís F. Grilo; Mariana S. Diniz; Carolina Tocantins; Ana Luísa Areia; Pereira SP, Obesities. 236 - 255. 3. 2. 2022. http://dx.doi.org/10.3390/obesities2030019 . 10.3390/obesities2030019 . Obesities

Exercise-Boosted Mitochondrial Remodeling in Parkinson's Disease

Juan Carlos MAGAÑA GALLARDO; Cláudia Deus; Deus, CM; Maria Giné-Garriga; Joel Montane; Pereira SP, Biomedicines. 3228 - 3228. 12. 10. 2022. http://dx.doi.org/10.3390/biomedicines10123228 . 10.3390/biomedicines10123228 . Biomedicines

The birth of cardiac disease: mechanisms linking gestational diabetes mellitus and early onset of cardiovascular disease in offspring

Carolina Tocantins; Mariana S. Diniz; Luís F. Grilo; Susana P. Pereira, WIREs Mechanisms of Disease. 2022. https://onlinelibrary.wiley.com/doi/10.1002/wsbm.1555 . 10.1002/wsbm.1555 . accepted WIREs Mechanisms of Disease

Maternal hepatic adaptations to obesity during pregnancy involve mitochondria dysfunction and oxidative stress and are lobe specific

Luís F. Grilo; João D. Martins; Mariana S. Diniz; Chiara H. Cavallaro; Carolina Tocantins; Inês Baldeiras; Teresa Cunha-Oliveira; et al, 2022. submitted

Maternal high-fat high-sucrose diet and gestational exercise modulate hepatic fat accumulation and liver mitochondrial respiratory capacity in mothers and male offspring

Stevanovic-Silva, Jelena; Beleza, Jorge; Coxito, Pedro; Pereira, Susana; Rocha, Hugo; Gaspar, Tiago Bordeira; Gärtner, Fátima; et al, Metabolism. 116. 2021. http://dx.doi.org/10.1016/j.metabol.2021.154704 . 10.1016/j.metabol.2021.154704 . Metabolism

Improving pollutants environmental risk assessment using a multi model toxicity determination with in vitro, bacterial, animal and plant model systems: The case of the herbicide alachlor

Susana P. Pereira; Sandra M.A. Santos; Maria A.S. Fernandes; Cláudia M. Deus; João D. Martins; Maria C. Pedroso de Lima; Joaquim A.F. Vicente; Romeu A. Videira; Amália S. Jurado, Environmental Pollution. 117239 - 117239. 286. 2021. https://doi.org/10.1016/j.envpol.2021.117239 . 10.1016/j.envpol.2021.117239 . accepted Environmental Pollution

Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction

Susana P. Pereira; Ludgero C. Tavares; Ana I. Duarte; Inês Baldeiras; Teresa Cunha-Oliveira; João D. Martins; Maria S. Santos; et al, Clinical Science. 2021. https://doi.org/10.1042/CS20201339 . 10.1042/CS20201339 . Clinical Science

The Alterations of Mitochondrial Function during NAFLD Progression—An Independent Effect of Mitochondrial ROS Production

Inês C. M. Simões; Ricardo Amorim; José Teixeira; Agnieszka Karkucinska-Wieckowska; Adriana Carvalho; Susana P. Pereira; Rui F. Simões; et al, International Journal of Molecular Sciences. 6848 - 6848. 13. 22. 2021. https://doi.org/10.3390/ijms22136848 . 10.3390/ijms22136848 . International Journal of Molecular Sciences

Metabolic Disease Programming: from Mitochondria to Epigenetics, Glucocorticoid Signaling and Beyond

Luis F. Grilo; Carolina Tocantins; Mariana S. Diniz; Rodrigo Mello Gomes; Paulo J. Oliveira; Paulo Matafome; Susana P. Pereira, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13625 . 10.1111/eci.13625 . European Journal of Clinical Investigation

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients

Cláudia M. Deus; Susana P. Pereira; Teresa Cunha-Oliveira; José Teixeira; Rui F. Simões; Fernando Cagide; Sofia Benfeito; et al, Redox Biology. 2021. https://doi.org/10.1016/j.redox.2021.102037 . 10.1016/j.redox.2021.102037 . Redox Biology

Corrigendum to ‘A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients’. [Redox Biology 45 (2021) 102037]

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Teixeira, José; Simões, Rui F.; Cagide, Fernando; Benfeito, Sofia; et al, Redox Biology. 47. 2021. http://dx.doi.org/10.1016/j.redox.2021.102117 . 10.1016/j.redox.2021.102117 . Redox Biology

P-cadherin induces anoikis-resistance of matrix-detached breast cancer cells by promoting pentose phosphate pathway and decreasing oxidative stress

Bárbara Sousa; Joana Pereira; Ricardo Marques; Luís F. Grilo; Susana P. Pereira; Vilma A. Sardão; Fernando Schmitt; Paulo J. Oliveira; Joana Paredes, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 2020. http://dx.doi.org/10.1016/j.bbadis.2020.165964 . 10.1016/j.bbadis.2020.165964 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Development of a 96-well based assay for kinetic determination of catalase enzymatic-activity in biological samples

Luís F. Grilo; João D. Martins; Chiara H. Cavallaro; Peter W. Nathanielsz; Paulo J. Oliveira; Susana P. Pereira, Toxicology in Vitro. 2020. http://dx.doi.org/10.1016/j.tiv.2020.104996 . 10.1016/j.tiv.2020.104996 . Toxicology in Vitro

Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects

Deus, Cláudia M.; Pereira, Susana P.; Cunha-Oliveira, Teresa; Pereira, Francisco B.; Raimundo, Nuno; Oliveira, Paulo J., Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 3. 1866. 2020. http://dx.doi.org/10.1016/j.bbadis.2019.165615 . 10.1016/j.bbadis.2019.165615 . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Mitochondrial respiratory states and rates

Gnaiger E; Aasander Frostner E; Abdul Karim N; Abdel-Rahman EA; Abumrad NA; Acuna-Castroviejo D; Adiele RC; Susana P. Pereira, MitoFit Preprint Arch. 2019. accepted MitoFit Preprint Arch

Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats

Pereira, Gonçalo C; Pereira, Susana P; Pereira, Francisco B; Lourenço, Nuno; Lumini, José A; Pereira, Claudia V; Bjork, James A; et al, Toxicological Sciences. 2019. http://dx.doi.org/10.1093/toxsci/kfz026 . 10.1093/toxsci/kfz026 . Toxicological Sciences

Metabolic and Phenotypic Characterization of Human Skin Fibroblasts After Forcing Oxidative Capacity

Susana P Pereira; Cláudia M Deus; Teresa L Serafim; Teresa Cunha-Oliveira; Paulo J Oliveira, Toxicological Sciences. 2018. https://doi.org/10.1093/toxsci/kfy068 . 10.1093/toxsci/kfy068 . Toxicological Sciences

Determination of metabolic viability and cell mass using a tandem resazurin/sulforhodamine B assay

Silva, F.S.G.; Starostina, I.G.; Ivanova, V.V.; Rizvanov, A.A.; Oliveira, P.J.; Pereira, S.P., Current Protocols in Toxicology. 1 - 15. 2016. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026657309&partnerID=MN8TOARS . 10.1002/cptx.1 . Current Protocols in Toxicology

Cardiac cytochrome c and cardiolipin depletion during anthracycline-induced chronic depression of mitochondrial function

Pereira, Gonçalo C; Pereira, Susana P; Tavares, Ludgero C; Carvalho, Filipa S; Magalhães-Novais, Silvia; Barbosa, Inês A; Santos, Maria S; et al, 95 - 104. 30. 2016. http://hdl.handle.net/10316/47559 . 10.1016/j.mito.2016.07.005 .

Analysis of Bj fibroblasts mitochondrial respiratory chain function under glucose starvation and exposure to different doses of rotenone: Implications for neurogenerative diseases

Ivanova, V.V.; Starostina, I.G.; Martynova, E.V.; Pereira, S.P.; Oliveira, P.J.; Rizvanov, A.A.; Ivanova, V. V.; et al, Genes and Cells. 40 - 46. 4. 10. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962218626&partnerID=MN8TOARS . Genes and Cells

Effects of moderate global maternal nutrient reduction on fetal baboon renal mitochondrial gene expression at 0.9 gestation

Pereira, Susana P.; Oliveira, Paulo J.; Tavares, Ludgero C.; Moreno, António J.; Cox, Laura A.; Nathanielsz, Peter W.; Nijland, Mark J., American Journal of Physiology-Renal Physiology. F1217 - F1228. 11. 308. 2015. http://dx.doi.org/10.1152/ajprenal.00419.2014 . 10.1152/ajprenal.00419.2014 . American Journal of Physiology-Renal Physiology

Gene Expression Profiling of H9c2 Myoblast Differentiation towards a Cardiac-Like Phenotype

Ana Branco; Susana P. Pereira; Susana Gonzalez; Oleg Gusev; Albert A. Rizvanov; Paulo J. Oliveira; Branco, Ana F.; et al, PLoS One. 1 - 10. 29. 2015. http://www.ncbi.nlm.nih.gov/pubmed/26121149 . 10.1371/journal.pone.0129303. . published PLoS One

Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats

Pereira, Susana P.; Pereira, Gonçalo C.; Pereira, Cláudia V.; Carvalho, Filipa S.; Cordeiro, Marília H.; Mota, Paula C.; Ramalho-Santos, João; Moreno, António J.; Oliveira, Paulo J., Environmental Pollution. 281 - 290. 180. 2013. http://dx.doi.org/10.1016/j.envpol.2013.05.049 . 10.1016/j.envpol.2013.05.049 . Environmental Pollution

Mitochondrionopathy phenotype in doxorubicin-treated Wistar rats depends on treatment protocol and is cardiac-specific

Pereira, Gonçalo C; Pereira, Susana P; Pereira, Claudia V; Lumini, José A; Magalhães, José; Ascensão, António; Santos, Maria S; et al, PLoS ONE. e38867 - e38867. 6. 7. 2012. http://hdl.handle.net/10316/47554 . 10.1371/journal.pone.0038867 . published PLoS ONE

Acute effects of TCDD administration: Special emphasis on testicular and sperm mitochondrial function

Mota, P.C.; Tavares, R.S.; Cordeiro, M.; Pereira, S.P.; Publicover, S.J.; Oliveira, P.J.; Ramalho-Santos, J.; et al, Asian Pacific Journal of Reproduction. 269 - 276. 4. 1. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929141935&partnerID=MN8TOARS . 10.1016/S2305-0500(13)60091-3 . published Asian Pacific Journal of Reproduction

Differential effects of p,p'-DDE on testis and liver mitochondria: implications for reproductive toxicology

Mota, Paula C; Cordeiro, Marília; Pereira, Susana P; Oliveira, Paulo J; Moreno, António J; Ramalho-Santos, João; Paula C. Mota; et al, Reproductive Toxicology. 80 - 85. 1. 31. 2011. http://hdl.handle.net/10316/47553 . 10.1016/j.reprotox.2010.09.010 . published Reproductive Toxicology

Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung

Machado, Nuno G; Baldeiras, Inês; Pereira, Gonçalo C; Pereira, Susana P; Oliveira, Paulo J; Nuno G. Machado; Inês Baldeiras; et al, Chemico-Biological Interactions. 478 - 486. 3. 188. 2010. http://hdl.handle.net/10316/47552 . 10.1016/j.cbi.2010.09.027 . published Chemico-Biological Interactions

Toxicity assessment of the herbicide metolachlor comparative effects on bacterial and mitochondrial model systems

Susana P. Pereira; Maria A.S. Fernandes; João D. Martins; Maria S. Santos; António J. Moreno; Joaquim A.F. Vicente; Romeu A. Videira; et al, Toxicology in Vitro. 1585 - 1590. 8. 23. 2009. http://www.sciencedirect.com/science/article/pii/S0887233309001702 . 10.1016/j.tiv.2009.06.032 . published Toxicology in Vitro

Investigating drug-induced mitochondrial toxicity: a biosensor to increase drug safety?

Pereira, Cláudia V; Moreira, Ana C; Pereira, Susana P; Machado, Nuno G; Carvalho, Filipa S; Sardão, Vilma A; Oliveira, Paulo J; et al, Current Drug Safety. 34 - 54. 1. 4. 2009. http://www.ncbi.nlm.nih.gov/pubmed/19149524 . 10.2174/157488609787354440 . Current Drug Safety

Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?

Pereira, S.P.; Pereira, G.C.; Moreno, A.J.; Oliveira, P.J., ATLA Alternatives to Laboratory Animals. 355 - 365. 4. 37. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449604749&partnerID=MN8TOARS . ATLA Alternatives to Laboratory Animals

Comparative effects of three 1,4-dihydropyridine derivatives [OSI-1210, OSI-1211 (etaftoron), and OSI-3802] on rat liver mitochondrial bioenergetics and on the physical properties of membrane lipid bilayers: Relevance to the length of the alkoxyl chain in positions 3 and 5 of the DHP ring

Fernandes, Maria A. S.; Pereira, Susana P. S.; Jurado, Amália S.; Custódio, José B. A.; Santos, Maria S.; Moreno, António J. M.; Duburs, Gunars; et al, The 1,4-dihydropyridines OSI-1210, OSI-1211 (etaftoron), and OSI-3802 are compounds with similar chemical structure. They differ by the length of the alkoxyl chain in positions 3 and 5 of the dihydropyridine (DHP) ring and by their pharmacological action characteristics. However, as far as we know, a clear relationship between the effects of these compounds and the length of the alkoxyl chain in p. 195 - 204. 3. 173. 2008. http://hdl.handle.net/10316/5293 . 10.1016/j.cbi.2008.03.001 . published The 1,4-dihydropyridines OSI-1210, OSI-1211 (etaftoron), and OSI-3802 are compounds with similar chemical structure. They differ by the length of the alkoxyl chain in positions 3 and 5 of the dihydropyridine (DHP) ring and by their pharmacological action characteristics. However, as far as we know, a clear relationship between the effects of these compounds and the length of the alkoxyl chain in p

Doxorubicin increases the susceptibility of brain mitochondria to Ca2+-induced permeability transition and oxidative damage

Susana Cardoso; Renato X. Santos; Cristina Carvalho; Sónia Correia; Gonçalo C. Pereira; Susana P. Pereira; Paulo J. Oliveira; et al, Free Radical Biology and Medicine. 1395 - 1402. 10. 45. 2008. http://www.sciencedirect.com/science/article/pii/S089158490800470X . 10.1016/j.freeradbiomed.2008.08.008 . published Free Radical Biology and Medicine

All projects

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Information of exclusive responsibility of the researcher 18-04-2024 , from platform CIÊNCIAVITAE.

2023/01 - 2023/11

ON-BOARD: Integrated tutoring program for the prevention of academic insuccess and abandonment at the University of Coimbra

ON-BOARD

Funders: European Social Fund

2023/03 - 2024/08

New therapeutic approaches to obesity based on peripheral dopaminergic signaling

2022.05822.PTDC

Researcher

Funders: Portuguese Foundation for Science and Technology

2023/03/01 - 2026/08/31

De-risking metabolic, environmental and behavioral determinants of obesity in children, adolescents and young adults

HORIZON-HLTH-2022-STAYHLTH- 101080329

Researcher

Universidade de Coimbra; Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas

Funders: European Commission

2023/03 -

Mitochondria as potential drivers of sex-specific microglia dysfunctional remodelling and anxiety caused by prenatal stress

EXPL/MED-NEU/1002/2021

Researcher

Portuguese Foundation for Science and Technology

2022/01 - 2023/12

BraveHEART: Improvig Nature by Addressing Bioactive Dietary Polyphenols to Mitochondria for the Protection of Cardiac Complications in Non-Alcoholic Fatty Liver Disease

EXPL/BIA-BQM/1361/2021

Researcher

2022/11 - 2023

MitoBOOST v2.0 - Proof of Concept for the Use of Mitochondrial Targeted Polyphenols to Treat Non-Alcoholic Fatty Liver Disease

CENTRO-01-0145-FEDER-181226

Researcher

CENTRO2020 Operational Program

2022/07 - 2023

Preservation of natural and cultural heritage and scientific validation of practices with medicinal plants from Côa Valley

COA/BRB/0019/2019

Researcher

Portuguese Foundation for Science and Technology

2022 -

Physical activity-induced metabolic and mitochondrial remodeling in fibroblasts from patients with Parkinson's disease

2022.01232.PTDC

Funders: Portuguese Foundation for Science and Technology

2020 - 2024

Centro de Investigação em Actividade Física, Saúde e Lazer Research Center in Physical Activity , Health and Leisure

UIDB/00617/2020

Researcher

2020 -

Assessment of mitochondrial function, using skin fibroblasts as a biomarker in patients with Parkinson's disease: effects of two physical activity programs on motor function, quality of life, sleep, cognitive aspects and mood

2021-URL-Proj-004

Funders: Ajuts a l’Activitat de Recerca del Personal Docent i Investigador de la Universitat Ramon Llull

2020 - 2025/12/31

Laboratório para a Investigação Integrativa e translacional em Saúde Populacional Laboratory for Integrative and Translational Research in Population Health

LA/P/0064/2020

Researcher

2018/06 - 2021

Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproducts

PTDC/ASP-HOR/29152/2017

Funders: Portuguese Foundation for Science and Technology

2017/09 -

EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring

SFRH/BPD/116061/2016

Post-doc Fellow

Universidade do Porto Faculdade de Desporto

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2017/01/01 - 2017/08/31

CANCEL_STEM: Tackling Cancer Stem: a challenge and an opportunity to advance in anti-cancer therapy

pro.no. 016390

Integration into Research Grant Fellow

Universidade do Porto Instituto de Investigação e Inovação em Saúde

Funders: Associação para a Inovação e Desenvolvimento da FCT

2016/05 - 2016/12

EXERCISING THE FUTURE: Voluntary Exercise During Gestational Diabetes as a Means to Improve Mitochondrial Function in the Offspring

PTDC/DTP-DES/1082/2014

Research Technician Fellow

Funders: Fundação para a Ciência e a Tecnologia

2014/07/01 - 2015/12/31

An Epigenetic Engineering Approach to Reverse the Parkinson Disease Cell State (PD-state)

PD-state

Science and Technology Management Fellow

Center for Neuroscience and Cell Biology

Funders: Foundation Montepio

2011/03 - 2014/08

Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction

Provided by PTCRIS: 110952

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/04 - 2013/09

Can Phytoestrogens be Safe and Effective Food Additives for Women During Menopause? - An In Vitro and In Vivo Approach to the problem.

108326

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/05 - 2013/10

Clarification of the Mitochondrial Role in the Cardiotoxicity of Doxorubicin Using a Whole Heart Perfusion System - Impact of Different Doxorubicin Treatment Regimens

104731

Funders: Ministério da Ciência Tecnologia e Ensino Superior

2007 - 2009

Influence of Cell Differentiation State on Apoptosis Induced by Isoproterenol on Embryonic Ventricular H9c2 Cells – Signaling Pathways Involved”

PTDC/SAU-OSM/64084/2006

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2007/09 - 2010/03

Novel Mitochondrial Mechanisms of Doxorubicin-induced Selective Cardiotoxicity

Provided by PTCRIS: 64084

Funders: Fundação para a Ciência e a Tecnologia, I.P.

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