Metabolism, Aging and Disease

Innate immunity in inflammatory pathologies

Inflammation

Immunotherapy

Pharmacology

Toxicology


Research lines

Development of dendritic cell-based therapies

Identification of new molecules with anti-inflammatory and neuroprotective properties

Development of non-animal approaches to detect skin and respiratory allergens

Development of medical devices to prevent skin allergy.

Overview

The research developed has focused mainly on the identification of the molecular mechanisms involved in peripheral and central inflammation with a special focus on macrophages, dendritic cells and epithelial barriers aiming to: i) screen anti-inflammatory drugs from natural endogenous resources; ii) develop non-animal approaches for immunotoxicity risk assessment; iii) develop immunotherapy strategies based on dendritic cells. For these purposes we use sub-cellular fractions, cell lines, primary cell cultures, mice and human samples as experimental models.

Publications

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Information about journal articles, updated at 29-12-2024, from platform CIÊNCIAVITAE.

Persulfated Ascorbic Acid Glycoside as a Safe and Stable Derivative of Ascorbic Acid for Skin Care Application

Ana Jesus; Marta Correia-da-Silva; Catarina Confraria; Sílvia Silva; Brites, G; Ana Isabel Sebastião; Mylène Carrascal; et al, 2024. Molecules. 2024. https://www.mdpi.com/1420-3049/29/19/4604 . 10.3390/molecules29194604 . Molecules

1,2-Dihydroxy-<i>9H</i>-Xanthen-9-One, a Multifunctional Nature-Inspired Active Ingredient

Ana Jesus; Sara F. Vieira; Brites, G; Mylène Carrascal; Helena Ferreira; Nuno M. Neves; Honorina Cidade; et al, 2024. Cosmetics. 2024. https://www.mdpi.com/2079-9284/11/6/215 . 10.3390/cosmetics11060215 . Cosmetics

Biological and phytochemical variation with pre- and post-harvest conditions for the Acanthus mollis L. leaf

Matos, Patrícia; Paranhos, António; Oliveiros, Bárbara; Cruz, Maria Teresa; Batista, Maria Teresa; Figueirinha, Artur, 2024. Industrial Crops and Products. 211. 2024. http://dx.doi.org/10.1016/j.indcrop.2024.118221 . 10.1016/j.indcrop.2024.118221 . Industrial Crops and Products

Effect of bioactive extracts from Eucalyptus globulus leaves in experimental models of Alzheimer’s disease

Moreira, Patrícia; Macedo, Jéssica; Matos, Patrícia; Bicker, Joana; Fortuna, Ana; Figueirinha, Artur; Salgueiro, Lígia; et al, 2024. Biomedicine &amp; Pharmacotherapy. 181. 2024. http://dx.doi.org/10.1016/j.biopha.2024.117652 . 10.1016/j.biopha.2024.117652 . published Biomedicine &amp; Pharmacotherapy

Unlocking the Bioactive Potential and Exploring Novel Applications for Portuguese Endemic Santolina impressa

Jorge M. Alves-Silva; Sónia Pedreiro; Mónica Zuzarte; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2024. Plants. 2024. https://doi.org/10.3390/plants13141943 . 10.3390/plants13141943 . Plants

Mannose and Lactobionic Acid in Nasal Vaccination: Enhancing Antigen Delivery via C-Type Lectin Receptors

Mariana Colaço; Maria T. Cruz; Luís Pereira de Almeida; Olga Borges, 2024. Pharmaceutics. 2024. https://doi.org/10.3390/pharmaceutics16101308 . 10.3390/pharmaceutics16101308 . Pharmaceutics

The study of galactomannans with different molecular weights and their ability to form microparticles suitable for pulmonary delivery

Galrinho, Miguel; Silva, Lisete; Lopes, Guido R.; Bernardo A. C. Ferreira; Valente, Sara A.; Isabel Ferreira; Pinheiro, Benedita; et al, 2024. Carbohydrate Polymers. 2024. under revision Carbohydrate Polymers

Exploring the immunomodulatory properties of glucan particles in human primary cells

Panão Costa, João; Jesus, Sandra; Colaço, Mariana; Lebre, Filipa; Mateus, Daniela; Sebastião, Ana Isabel; Cruz, Maria Teresa; Alfaro-Moreno, Ernesto; Borges, Olga, 2024. International Journal of Pharmaceutics. 123996. 655. 2024. https://www.sciencedirect.com/science/article/pii/S0378517324002308?via%3Dihub . published International Journal of Pharmaceutics

How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies

Ana Torres; Liliana Rego; Márcia S. Martins; Marta S. Ferreira; Maria T. Cruz; Emília Sousa; Isabel F. Almeida, 2023. Pharmaceuticals. 2023. https://doi.org/10.3390/ph16040573 . 10.3390/ph16040573 . Pharmaceuticals

A Hydrophilic Sulfated Resveratrol Derivative for Topical Application: Sensitization and Anti-Allergic Potential

Ana Jesus; Ana I. Sebastião; Gonçalo Brites; Marta Correia-da-Silva; Honorina Cidade; Maria T. Cruz; Emília Sousa; Isabel F. Almeida, 2023. Molecules. 2023. https://doi.org/10.3390/molecules28073158 . 10.3390/molecules28073158 . Molecules

Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells

B.J. Conti; K.B. Santiago; E.O. Cardoso; F.L. Conte; M.A. Golim; M.T. Cruz; J.M. Sforcin, 2023. Brazilian Journal of Medical and Biological Research. 2023. https://doi.org/10.1590/1414-431x2023e12659 . 10.1590/1414-431x2023e12659 . Brazilian Journal of Medical and Biological Research

CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell Activation and Th1 Polarization

Ana Isabel Sebastião; Daniela Mateus; Mylène A. Carrascal; Cátia Sousa; Luísa Cortes; Martin F. Bachmann; Anália do Carmo; et al, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15030825 . 10.3390/pharmaceutics15030825 . Pharmaceutics

Exploiting the Integrated Valorization of Eucalyptus globulus Leaves: Chemical Composition and Biological Potential of the Lipophilic Fraction before and after Hydrodistillation

Cátia. S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Artur M. S. Silva; Sónia A. O. Santos; Armando J. D. Silvestre, 2023. International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms24076226 . 10.3390/ijms24076226 . International Journal of Molecular Sciences

Polysaccharide-Based Carriers for Pulmonary Insulin Delivery: The Potential of Coffee as an Unconventional Source

Sara A. Valente; Guido R. Lopes; Isabel Ferreira; Miguel F. Galrinho; Margarida Almeida; Paula Ferreira; Maria T. Cruz; Manuel A. Coimbra; Cláudia P. Passos, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15041213 . 10.3390/pharmaceutics15041213 . Pharmaceutics

Chemical Profile, Anti-Microbial and Anti-Inflammaging Activities of Santolina rosmarinifolia L. Essential Oil from Portugal

Jorge M. Alves-Silva; Maria José Gonçalves; Ana Silva; Carlos Cavaleiro; Maria Teresa Cruz; Lígia Salgueiro, 2023. Antibiotics. 2023. https://doi.org/10.3390/antibiotics12010179 . 10.3390/antibiotics12010179 . Antibiotics

Unveiling the Chemical Composition and Biological Properties of Salvia cacaliifolia Benth. Essential Oil

Jorge M. Alves-Silva; Emma Cocco; Alessandra Piras; Maria José Gonçalves; Ana Silva; Danilo Falconieri; Silvia Porcedda; et al, 2023. Plants. 2023. https://doi.org/10.3390/plants12020359 . 10.3390/plants12020359 . Plants

Advances in the Phytochemical Characterisation and Bioactivities of Salvia aurea L. Essential Oil

Jorge Miguel Alves-Silva; Delia Maccioni; Emma Cocco; Maria José Gonçalves; Silvia Porcedda; Alessandra Piras; Maria Teresa Cruz; Lígia Salgueiro; Andrea Maxia, 2023. Plants. 2023. https://doi.org/10.3390/plants12061247 . 10.3390/plants12061247 . Plants

Antioxidants in Sunscreens: Which and What For?

Ana Jesus; Sandra Mota; Ana Torres; Maria T. Cruz; Emília Sousa; Isabel F. Almeida; Honorina Cidade, 2023. Antioxidants. 2023. https://doi.org/10.3390/antiox12010138 . 10.3390/antiox12010138 . Antioxidants

Effect of Thymbra capitata (L.) Cav. on Inflammation, Senescence and Cell Migration

Jorge M. Alves-Silva; Sónia Pedreiro; Carlos Cavaleiro; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2023. Nutrients. 2023. https://doi.org/10.3390/nu15081930 . 10.3390/nu15081930 . Nutrients

Artificial Dendritic Cells: A New Era of Promising Antitumor Immunotherapy

Daniela Mateus; Ana I. Sebastião; Manuela F. Frasco; Mylène A. Carrascal; Amílcar Falcão; Célia M. Gomes; Bruno Neves; Maria G. F. Sales; Maria T. Cruz, 2023. Small. 2023. https://doi.org/10.1002/smll.202303940 . 10.1002/smll.202303940 . Small

An integrated green process for the extraction of triterpenic acids from Eucalyptus globulus leaves after hydrodistillation

Cátia S. D. Oliveira; Patrícia Moreira; Maria T. Cruz; Cláudia M. F. Pereira; Alexandre Gaspar; Carlos Pascoal Neto; Paula C. R. O. Pinto; et al, 2023. RSC Sustainability. 2023. https://doi.org/10.1039/D3SU00076A . 10.1039/D3SU00076A . RSC Sustainability

Lipidome of extracellular vesicles from Giardia lamblia

Clarissa Perez Faria; Maria de Fátima Matos Almeida Henriques de Macedo; Barbara Ferreira; Ágata Lourenço; Inês Guerra; Tânia Melo; Pedro Domingues; et al, 2023. PLOS ONE. 2023. https://doi.org/10.1371/journal.pone.0291292 . 10.1371/journal.pone.0291292 . PLOS ONE

Development of an in chemico high-throughput screening method for the identification of skin sensitization potential

Isabel Ferreira; Gonçalo Brites; Ana Silva; Francisco Caramelo; Bárbara Oliveiros; Bruno Miguel Neves; Maria Teresa Cruz, 2023. Archives of Toxicology. 2023. https://doi.org/10.1007/s00204-023-03550-z . 10.1007/s00204-023-03550-z . Archives of Toxicology

The Effect of Curcumin-Loaded Glucan Nanoparticles on Immune Cells: Size as a Critical Quality Attribute

Mariana Colaço; Tiago Roquito; João Panão Costa; Maria Teresa Cruz; Olga Borges, 2023. Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15020623 . 10.3390/pharmaceutics15020623 . Pharmaceutics

Exploring the Traditional Uses of <i>Thymbra capitata</i> Infusion in Algarve (Portugal): Anti-Inflammatory, Wound Healing, and Anti-Aging

Jorge Miguel Alves-Silva; Sónia Pedreiro; Cruz MT; Salgueiro L.; Artur Figueirinha, 2023. Pharmaceuticals. 2023. https://www.mdpi.com/1424-8247/16/9/1202 . 10.3390/ph16091202 . Pharmaceuticals

Comparative Studies on the Photoreactivity, Efficacy, and Safety of Depigmenting Agents

Sandra Mota; Gonçalo P. Rosa; Maria Carmo Barreto; Jorge Garrido; Emília Sousa; Maria T. Cruz; Isabel F. Almeida; Clara Quintas, 2023. Pharmaceuticals. 2023. https://doi.org/10.3390/ph17010055 . 10.3390/ph17010055 . Pharmaceuticals

Chemical Composition and Effect against Skin Alterations of Bioactive Extracts Obtained by the Hydrodistillation of <i>Eucalyptus globulus</i> Leaves

Patrícia Moreira; Fábio J. Sousa; Patrícia Matos; Brites, G; Maria José Gonçalves; Carlos Cavaleiro; Artur Figueirinha; et al, 2022. Pharmaceutics. 2022. https://www.mdpi.com/1999-4923/14/3/561 . 10.3390/pharmaceutics14030561 . Pharmaceutics

ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system

2022. Cellular and Molecular Life Sciences. 4. 79. 2022. http://dx.doi.org/10.1007/s00018-022-04211-7 . 10.1007/s00018-022-04211-7 . Cellular and Molecular Life Sciences

Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer’s disease: Past, present and future

2022. Ageing Research Reviews. 101612 - 101612. 77. 2022. http://dx.doi.org/10.1016/j.arr.2022.101612 . 10.1016/j.arr.2022.101612 . Ageing Research Reviews

Development of colorimetric cellulose-based test-strip for the rapid detection of antibodies against SARS-CoV2 virus.

Cruz MT, 2022. Cellulose (London, England). 2022. https://europepmc.org/articles/PMC9483301 . 10.1007/s10570-022-04808-y . Cellulose (London, England)

UV Filters: Challenges and Prospects

Ana Jesus; Emília Sousa; Maria T. Cruz; Honorina Cidade; José M. Sousa Lobo; Isabel F. Almeida, 2022. Pharmaceuticals. 263 - 263. 3. 15. 2022. https://doi.org/10.3390/ph15030263 . 10.3390/ph15030263 . Pharmaceuticals

Exploring the antioxidant, anti-inflammatory and antiallergic potential of Brazilian propolis in monocytes

2022. Phytomedicine Plus. 100231 - 100231. 2. 2. 2022. http://dx.doi.org/10.1016/j.phyplu.2022.100231 . 10.1016/j.phyplu.2022.100231 . Phytomedicine Plus

Mitochondria Fusion upon SERCA Inhibition Prevents Activation of the NLRP3 Inflammasome in Human Monocytes

Ana Catarina Pereira; Nuno Madeira; Sofia Morais; António Macedo; Maria Teresa Cruz; Cláudia M. F. Pereira, 2022. Cells. 433 - 433. 3. 11. 2022. https://doi.org/10.3390/cells11030433 . 10.3390/cells11030433 . Cells

The Anti-Inflammatory Response of Lavandula luisieri and Lavandula pedunculata Essential Oils

Monica Zuzarte; Cátia Sousa; Carlos Cavaleiro; Maria Teresa Cruz; Lígia Salgueiro, 2022. Plants. 2022. https://doi.org/10.3390/plants11030370 . 10.3390/plants11030370 . Plants

Up-to-Date Overview of the Use of Natural Ingredients in Sunscreens

Diana I. S. P. Resende; Ana Jesus; José M. Sousa Lobo; Emília Sousa; Maria T. Cruz; Honorina Cidade; Isabel F. Almeida, 2022. Pharmaceuticals. 372 - 372. 3. 15. 2022. https://doi.org/10.3390/ph15030372 . 10.3390/ph15030372 . Pharmaceuticals

Improvement of Glycaemia and Endothelial Function by a New Low-Dose Curcuminoid in an Animal Model of Type 2 Diabetes

Sara Oliveira; Tamaeh Monteiro-Alfredo; Rita Henriques; Carlos Fontes Ribeiro; Raquel Seiça; Teresa Cruz; Célia Cabral; et al, 2022. International Journal of Molecular Sciences. 5652 - 5652. 10. 23. 2022. https://doi.org/10.3390/ijms23105652 . 10.3390/ijms23105652 . International Journal of Molecular Sciences

Forest Biomass as a Promising Source of Bioactive Essential Oil and Phenolic Compounds for Alzheimer’s Disease Therapy

Patrícia Moreira; Patrícia Matos; Artur Figueirinha; Lígia Salgueiro; Maria Teresa Batista; Pedro Costa Branco; Maria Teresa Cruz; Cláudia Fragão Pereira, 2022. International Journal of Molecular Sciences. 2022. https://doi.org/10.3390/ijms23158812 . 10.3390/ijms23158812 . International Journal of Molecular Sciences

An ultra-sensitive electrochemical biosensor using the Spike protein for capturing antibodies against SARS-CoV-2 in point-of-care

Cardoso, Ana Rita; João Frederico Alves; Frasco, Manuela F; Ana Margarida L. Piloto; Serrano, Verónica; Mateus, Daniela; Sebastião, Ana Isabel; et al, 2022. Materials Today Bio. 100354. 16. 2022. published Materials Today Bio

Recent Trends on UV filters

Ana Jesus; Inês Augusto; Joana Duarte; Emília Sousa; Honorina Cidade; Maria T. Cruz; José M. Sousa Lobo; Isabel F. Almeida, 2022. Applied Sciences. 2022. https://doi.org/10.3390/app122312003 . 10.3390/app122312003 . Applied Sciences

Protective role of Portuguese natural mineral waters on skin aging: in vitro evaluation of anti-senescence and anti-oxidant properties.

Vaz CV; Oliveira AS; Silva A; Cortes L; Correia S; Ferreira R; Breitenfeld L; et al, 2022. International journal of biometeorology. 2022. http://europepmc.org/abstract/med/35994120 . 10.1007/s00484-022-02345-8 . International journal of biometeorology

Lavandula viridis L´Hér. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade

Zuzarte, Monica; Francisco, Vera; Neves, Bruno; Liberal, Joana; Cavaleiro, Carlos; Canhoto, Jorge; Salgueiro, Lígia; Cruz, Maria Teresa; Salgueiro, Ligia, 2022. Frontiers in Pharmacology. 12. 2022. http://dx.doi.org/10.3389/fphar.2021.695911 . 10.3389/fphar.2021.695911 . Frontiers in Pharmacology

Impact of Gastrointestinal Digestion on the Anti-Inflammatory Properties of Phlorotannins from Himanthalia elongata

Marcelo D. Catarino; Ana Rita Circuncisão; Bruno Neves; Catarina Marçal; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso, 2022. Antioxidants. 2022. https://doi.org/10.3390/antiox11081518 . 10.3390/antiox11081518 . Antioxidants

Antifungal and Anti-Inflammatory Potential of Bupleurum rigidum subsp. paniculatum (Brot.) H.Wolff Essential Oil

Mónica Zuzarte; Pedro M. P. Correia; Jorge M. Alves-Silva; Maria J. Gonçalves; Carlos Cavaleiro; Teresa Cruz; Lígia Salgueiro, 2021. Antibiotics. 592 - 592. 5. 10. 2021. https://doi.org/10.3390/antibiotics10050592 . 10.3390/antibiotics10050592 . Antibiotics

Anti-Inflammatory Activity of Calendula officinalis L. Flower Extract

Diva Silva; Marta Salvador Ferreira; José Manuel Sousa-Lobo; Maria Teresa Cruz; Isabel Filipa Almeida, 2021. Cosmetics. 2021. https://doi.org/10.3390/cosmetics8020031 . 10.3390/cosmetics8020031 . Cosmetics

Antitumor Activity of Fucus vesiculosus-Derived Phlorotannins through Activation of Apoptotic Signals in Gastric and Colorectal Tumor Cell Lines

Marcelo D. Catarino; Iva Fernandes; Hélder Oliveira; Mylene Carrascal; Rita Ferreira; Artur M. S. Silva; Maria Teresa Cruz; Nuno Mateus; Susana M. Cardoso, 2021. International Journal of Molecular Sciences. 7604 - 7604. 14. 22. 2021. https://doi.org/10.3390/ijms22147604 . 10.3390/ijms22147604 . International Journal of Molecular Sciences

Pharmacological combination of nivolumab with dendritic cell vaccines in cancer immunotherapy: An overview

Calmeiro, J.; Carrascal, M.A.; Tavares, A.R.; Ferreira, D.A.; Gomes, C.; Cruz, M.T.; Falcão, A.; et al, 2021. Pharmacological Research. 164. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85099552475&partnerID=MN8TOARS . 10.1016/j.phrs.2020.105309 . Pharmacological Research

Exosomes as new therapeutic vectors for pancreatic cancer treatment

Oliveira, Constanca; Calmeiro, Joao; Carrascal, Mylene A.; Falcao, Amilcar; Gomes, Celia; Neves, Bruno Miguel; Cruz, Maria Teresa, 2021. European Journal of Pharmaceutics and Biopharmaceutics. 2021. https://publons.com/publon/39705379/ . 10.1016/J.EJPB.2021.02.002 . European Journal of Pharmaceutics and Biopharmaceutics

Propolis from southeastern Brazil produced by Apis mellifera affects innate immunity by modulating cell marker expression, cytokine production and intracellular pathways in human monocytes

Conte, Fernanda Lopes; Santiago, Karina Basso; Conti, Bruno Jose; Cardoso, Eliza de Oliveira; Garcia Oliveira, Lucas Pires; Feltran, Georgia da Silva; Zambuzzi, Willian Fernando; et al, 2021. Journal of Pharmacy and Pharmacology. 135 - 144. 2. 73. 2021. https://publons.com/publon/46053419/ . 10.1093/JPP/RGAA023 . Journal of Pharmacy and Pharmacology

Crosstalk between estrogen, dendritic cells, and SARS-CoV-2 infection

Mateus, Daniela; Sebastiao, Ana Isabel; Carrascal, Mylene A.; do Carmo, Analia; Matos, Ana Miguel; Cruz, Maria Teresa; Mateus, D.; et al, 2021. Reviews in Medical Virology. 2021. https://publons.com/publon/49453726/ . 10.1002/RMV.2290 . Reviews in Medical Virology

Chemical composition and biological activity of essential oil of Teucrium scordium L. subsp. scordioides (Schreb.) Arcang. (Lamiaceae) from Sardinia Island (Italy)

Piras, A.; Maccioni, A.; Falconieri, D.; Porcedda, S.; Gonçalves, M.J.; Alves-Silva, J.M.; Silva, A.; et al, 2021. Natural Product Research. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85121839185&partnerID=MN8TOARS . 10.1080/14786419.2021.2018432 . Natural Product Research

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Pinheiro, T.; Cardoso, A.R.; Sousa, C.E.A.; Marques, A.C.; Tavares, A.P.M.; Matos, A.M.; Cruz, M.T.; et al, 2021. ACS Omega. 29268 - 29290. 44. 6. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85118899020&partnerID=MN8TOARS . 10.1021/acsomega.1c04012 . ACS Omega

Chemical characterization and bioactive potential of Artemisia campestris L. subsp. maritima (DC) Arcang. essential oil and hydrodistillation residual water

Rocha, M.I.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Pereira, C.; Moreira, P.; Salgueiro, L.; et al, 2021. Journal of Ethnopharmacology. 276. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85105307700&partnerID=MN8TOARS . 10.1016/j.jep.2021.114146 . Journal of Ethnopharmacology

In-Depth Analysis of the Impact of Different Serum-Free Media on the Production of Clinical Grade Dendritic Cells for Cancer Immunotherapy

Calmeiro, J.; Mendes, L.; Duarte, I.F.; Leitão, C.; Tavares, A.R.; Ferreira, D.A.; Gomes, C.; et al, 2021. Frontiers in Immunology. 11. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85101266995&partnerID=MN8TOARS . 10.3389/fimmu.2020.593363 . Frontiers in Immunology

Role of Coffee Caffeine and Chlorogenic Acids Adsorption to Polysaccharides with Impact on Brew Immunomodulation Effects

Cláudia P. Passos; Rita M. Costa; Sónia S. Ferreira; Guido R. Lopes; Maria T. Cruz; Manuel A. Coimbra, 2021. Foods. 2021. https://doi.org/10.3390/foods10020378 . 10.3390/foods10020378 . Foods

Therapies for Alzheimer's disease: a metabolic perspective

Domingues, R.; Pereira, C.; Cruz, M.T.; Silva, A.; Domingues, Raquel; Pereira, Claudia; Cruz, Maria Teresa; Silva, Ana, 2021. Molecular Genetics and Metabolism. 162 - 172. 3. 132. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85100399064&partnerID=MN8TOARS . 10.1016/j.ymgme.2021.01.011 . Molecular Genetics and Metabolism

Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer’s Disease Cellular Models

Ana Silva; Marta Pereira; Mylène Carrascal; Brites, G; Neves BM; Patrícia Moreira; Rosa Resende; et al, 2020. International Journal of Molecular Sciences. 2020. https://www.mdpi.com/1422-0067/21/20/7791 . 10.3390/ijms21207791 . International Journal of Molecular Sciences

In vitro evaluation of potential benefits of a silica-rich thermal water (Monfortinho Thermal Water) in hyperkeratotic skin conditions

Ana Sofia Oliveira; Cátia Vicente Vaz; Ana Silva; Sara Correia; Raquel Ferreira; Luiza Breitenfeld; José Martinez-de-Oliveira; et al, 2020. International Journal of Biometeorology. 2020. https://doi.org/10.1007/s00484-020-01986-x . 10.1007/s00484-020-01986-x . International Journal of Biometeorology

Allergic contact dermatitis: From pathophysiology to development of new preventive strategies

Gonçalo Sousa Brites; Isabel Ferreira; Ana Isabel Sebastião; Ana Silva; Mylene Carrascal; Bruno Miguel Neves; Maria T. Cruz, 2020. Pharmacological Research. 105282 - 105282. 2020. https://doi.org/10.1016/j.phrs.2020.105282 . 10.1016/j.phrs.2020.105282 . Pharmacological Research

Crepis vesicaria L. subsp. taraxacifolia Leaves: Nutritional Profile, Phenolic Composition and Biological Properties

Sónia Pedreiro; Sandrine da Ressurreição; Maria Lopes; Maria Teresa Cruz; Teresa Batista; Artur Figueirinha; Fernando Ramos, 2020. International Journal of Environmental Research and Public Health. 2020. https://doi.org/10.3390/ijerph18010151 . 10.3390/ijerph18010151 . International Journal of Environmental Research and Public Health

Dendritic Cell Vaccines for Cancer Immunotherapy: The Role of Human Conventional Type 1 Dendritic Cells

Calmeiro, João; Carrascal, Mylène A.; Tavares, Adriana Ramos; Ferreira, Daniel Alexandre; Gomes, Célia; Falcão, Amílcar; Cruz, Maria Teresa; et al, 2020. Pharmaceutics. 2. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12020158 . 10.3390/pharmaceutics12020158 . Pharmaceutics

Phlorotannins from Fucus vesiculosus: Modulation of Inflammatory Response by Blocking NF-¿B Signaling Pathway

Marcelo D. Catarino; Ana Silva; Maria T. Cruz; Nuno Mateus; Artur M.S. Silva; Susana M. Cardoso, 2020. International Journal of Molecular Sciences. 2020. https://doi.org/10.3390/ijms21186897 . 10.3390/ijms21186897 . International Journal of Molecular Sciences

NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify

Ana Isabel Sebastião; Isabel Ferreira; Gonçalo Brites; Ana Silva; Bruno Miguel Neves; Maria Teresa Cruz, 2020. Pharmaceutics. 867 - 867. 9. 12. 2020. https://doi.org/10.3390/pharmaceutics12090867 . 10.3390/pharmaceutics12090867 . Pharmaceutics

Chemical composition of Crithmum maritimum L. essential oil and hydrodistillation residual water by GC-MS and HPLC-DAD-MS/MS, and their biological activities

Jorge M. Alves-Silva; Inês Guerra; Maria José Gonçalves; Carlos Cavaleiro; Maria Teresa Cruz; Artur Figueirinha; Lígia Salgueiro, 2020. Industrial Crops and Products. 112329 - 112329. 149. 2020. https://doi.org/10.1016/j.indcrop.2020.112329 . 10.1016/j.indcrop.2020.112329 . Industrial Crops and Products

Giardia lamblia Decreases NF-kappa B p65(RelA) Protein Levels and Modulates LPS-Induced Pro-Inflammatory Response in Macrophages

Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenco, Agata; Cruz, Maria Teresa; Martins, Joao D.; Silva, Ana; Pereira, Sonia; et al, 2020. Scientific Reports. 1. 10. 2020. https://publons.com/publon/932727/ . 10.1038/S41598-020-63231-0 . published Scientific Reports

Inflammation in Bipolar Disorder (BD): Identification of New Therapeutic Targets

Ana Catarina Pereira; Joana Oliveira; Sónia Silva; Nuno Madeira; Cláudia MF Pereira; Maria T Cruz; Oliveira, Joana; et al, 2020. Pharmacological Research. 163. 2020. https://publons.com/publon/34012396/ . 10.1016/J.PHRS.2020.105325 . Pharmacological Research

Chemical characterization and bioactivity of the essential oil from Santolina insularis, a Sardinian endemism

Alves-Silva, J.M.; Piras, A.; Porcedda, S.; Falconieri, D.; Maxia, A.; Gonçalves, M.J.; Cruz, M.T.; Salgueiro, L., 2020. Natural Product Research. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85086880740&partnerID=MN8TOARS . 10.1080/14786419.2020.1774764 . Natural Product Research

Characterization and Cytotoxicity Assessment of the Lipophilic Fractions of Different Morphological Parts of Acacia dealbata

Oliveira, Catia S. D.; Moreira, Patricia; Resende, Judite; Cruz, Maria T.; Pereira, Claudia M. F.; Silva, Artur M. S.; Santos, Sonia A. O.; et al, 2020. International Journal of Molecular Sciences. 5. 21. 2020. https://publons.com/publon/32969534/ . 10.3390/IJMS21051814 . International Journal of Molecular Sciences

Chemical signature and antimicrobial activity of Central Portuguese Natural Mineral Waters against selected skin pathogens

Oliveira, A.S.; Vaz, C.V.; Silva, A.; Ferreira, S.S.; Correia, S.; Ferreira, R.; Breitenfeld, L.; et al, 2020. Environmental Geochemistry and Health. 2039 - 2057. 7. 42. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076109661&partnerID=MN8TOARS . 10.1007/s10653-019-00473-6 . Environmental Geochemistry and Health

Evaluating Skin Sensitization Via Soft and Hard Multivariate Modeling

Silva, F.A.L.S.; Brites, G.; Ferreira, I.; Silva, A.; Miguel Neves, B.; Costa Pereira, J.L.G.F.S.; Cruz, M.T., 2020. International Journal of Toxicology. 547 - 559. 6. 39. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85089197709&partnerID=MN8TOARS . 10.1177/1091581820944395 . International Journal of Toxicology

Antifungal and anti-inflammatory potential of the endangered aromatic plant Thymus albicans

Roxo, Mariana; Zuzarte, Monica; Goncalves, Maria Jose; Alves-Silva, Jorge M.; Cavaleiro, Carlos; Cruz, Maria Teresa; Salgueiro, Ligia; et al, 2020. Scientific Reports. 1. 10. 2020. https://publons.com/publon/36630873/ . 10.1038/S41598-020-75244-W . Scientific Reports

Nanostructuring lipid carriers using Ridolfia segetum (L.) Moris essential oil

Miranda, M.; Cruz, M.T.; Vitorino, C.; Cabral, C.; Miranda, Margarida; Cruz, Maria Teresa; Vitorino, Carla; Cabral, Celia, 2019. Materials Science and Engineering C. 103. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85066465144&partnerID=MN8TOARS . 10.1016/j.msec.2019.109804 . Materials Science and Engineering C

Unveiling the bioactive potential of the essential oil of a Portuguese endemism, Santolina impressa

Alves-Silva, J.M.; Zuzarte, M.; Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Salgueiro, L.; Alves-Silva, J. M.; Goncalves, M. J.; Cruz, M. T., 2019. Journal of Ethnopharmacology. 244. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070094953&partnerID=MN8TOARS . 10.1016/j.jep.2019.112120 . Journal of Ethnopharmacology

Is Alzheimer's disease an inflammasomopathy?

Pereira, C.F.; Santos, A.E.; Moreira, P.I.; Pereira, A.C.; Sousa, F.J.; Cardoso, S.M.; Cruz, M.T.; et al, 2019. Ageing Research Reviews. 56. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072809334&partnerID=MN8TOARS . 10.1016/j.arr.2019.100966 . Ageing Research Reviews

The role of endoplasmic reticulum stress in the innate immune system in bipolar disorder

Pereira, A. C.; Ferreira, I.; Neves, B.; Moura, D.; Morais, S.; Madeira, N.; Macedo, A.; Cruz, M. T.; Pereira, C., 2019. European Psychiatry. 2019. https://publons.com/publon/30841015/ . European Psychiatry

Development of a curcumin derivative with hypoglycemic properties: Impact on oxidative stress and endothelial function in type 2 diabetes

Oliveira, Sara; Monteiro, Tamaeh; Henriques, Rita; Aspercada, Luis; Ribeiro, Carlos Fontes; Seica, Raquel; Cruz, Teresa; et al, 2019. European Journal of Clinical Investigation. 2019. https://publons.com/publon/30741253/ . European Journal of Clinical Investigation

Biomaterial-based platforms for in situ dendritic cell programming and their use in antitumor immunotherapy

Calmeiro, Joao; Carrascal, Mylene; Gomes, Celia; Falcao, Amilcar; Cruz, Maria Teresa; Neves, Bruno Miguel; Calmeiro, J.; et al, 2019. Journal for ImmunoTherapy of Cancer. 1. 7. 2019. https://publons.com/publon/22830157/ . 10.1186/S40425-019-0716-8 . Journal for ImmunoTherapy of Cancer

Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation

Paiva, Rafael Almeida; Martins-Marques, Tania; Jesus, Katia; Ribeiro-Rodrigues, Teresa; Zuzarte, Monica; Silva, Ana; Reis, Liliana; et al, 2019. Journal of Cellular and Molecular Medicine. 2019. https://publons.com/publon/18866715/ . 10.1111/JCMM.14014 . Journal of Cellular and Molecular Medicine

A defined approach for skin sensitization potency integrating in silico, in chemico and in vitro cell data

Ferreira, I.; Brites, G.; Silva, A.; Cruz, M. T.; Neves, B. M., 2019. Toxicology Letters. 2019. https://publons.com/publon/26807094/ . Toxicology Letters

Chimeric Antigenic Receptor (CAR) T Cells: A New Immunotherapeutic Strategy

Cruz, Maria Teresa; Mateus, Daniela Marques; Borges, Olga, 2019. 2019. http://revista.farmacoterapia.pt/index.php/rpf/article/view/222 . 10.25756/rpf.v11i2-3.219 .

Células Estaminais Pluripotentes Induzidas no Tratamento da Doença de Alzheimer

Cruz, Maria Teresa; Marinheira, Joana; Silva, Sónia; Marinheira, Joana Filipa Rodrigues, 2019. 2019. http://www.actafarmaceuticaportuguesa.com/index.php/afp/article/view/190 .

Development of a novel dendritic cell-based immunotherapy targeting cancer stem cells

Calmeiro, Joao; Carrascal, Mylene; Mendes, Luis; Duarte, Iola F.; Gomes, Celia; Serra, Joao; Falcao, Amilcar; Cruz, Maria Teresa; Neves, Bruno Miguel, 2019. Journal of Clinical Oncology. 2019. https://publons.com/publon/21604203/ . 10.1200/JCO.2019.37.15_SUPPL.E14009 . Journal of Clinical Oncology

Unveiling the antifungal potential of two iberian thyme essential oils: Effect on C. albicans germ tube and preformed biofilms

Alves, M.; Gonçalves, M.J.; Zuzarte, M.; Alves-Silva, J.M.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L.; et al, 2019. Frontiers in Pharmacology. MAY. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85068820197&partnerID=MN8TOARS . 10.3389/fphar.2019.00446 . Frontiers in Pharmacology

Apple pomace extract as a sustainable food ingredient

Fernandes, P.A.R.; Ferreira, S.S.; Bastos, R.; Ferreira, I.; Cruz, M.T.; Pinto, A.; Coelho, E.; et al, 2019. Antioxidants. 6. 8. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069685332&partnerID=MN8TOARS . 10.3390/antiox8060189 . Antioxidants

Oxidized phosphatidylserine mitigates LPS-triggered macrophage inflammatory status through modulation of JNK and NF-kB signaling cascades

Maciel, Elisabete; Neves, Bruno M.; Martins, Joao; Colombo, Simone; Cruz, Maria Teresa; Domingues, Pedro; Domingues, M. Rosario M.; Cruz, Maria Teresa, 2019. Cellular Signalling. 2019. https://publons.com/publon/20224929/ . 10.1016/J.CELLSIG.2019.04.015 . Cellular Signalling

The cellular stress response in the immune system

Pereira, Claudia; Pereira, Ana Catarina; Ferreira, Isabel; Neves, Bruno; Morais, Sofia; Madeira, Nuno; Santos, Vitor; Macedo, Antonio; Cruz, Maria Teresa, 2019. European Journal of Clinical Investigation. 2019. https://publons.com/publon/26807090/ . European Journal of Clinical Investigation

Polyphenolic characterisation and bioactivity of an Oxalis pes-caprae L. leaf extract

Gaspar, M.C.; Fonseca, D.A.; Antunes, M.J.; Frigerio, C.; Gomes, N.G.M.; Vieira, M.; Santos, A.E.; et al, 2018. Natural Product Research. 732 - 738. 6. 32. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021073702&partnerID=MN8TOARS . 10.1080/14786419.2017.1335728 . Natural Product Research

New insights on the anti-inflammatory potential and safety profile of Thymus carnosus and Thymus camphoratus essential oils and their main compounds

Zuzarte, M.; Alves-Silva, J.M.; Alves, M.; Cavaleiro, C.; Salgueiro, L.; Cruz, M.T.; Zuzarte, Monica; et al, 2018. Journal of Ethnopharmacology. 10 - 17. 225. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049324707&partnerID=MN8TOARS . 10.1016/j.jep.2018.06.025 . Journal of Ethnopharmacology

Exosomes as adjuvants for the recombinant hepatitis B antigen: First report

Sandra Jesus; Edna Soares; Maria Teresa Cruz; Olga Borges; Jesus, Sandra; Soares, Edna; Cruz, Maria Teresa; Borges, Olga, 2018. European Journal of Pharmaceutics and Biopharmaceutics. 1 - 11. 133. 2018. https://doi.org/10.1016/j.ejpb.2018.09.029 . 10.1016/j.ejpb.2018.09.029 . European Journal of Pharmaceutics and Biopharmaceutics

Acanthus mollis L. leaves as source of anti-inflammatory and antioxidant phytoconstituents

Cruz, Maria Teresa, 2018. 2018. http://dx.doi.org/10.1080/14786419.2018.1437438 . 10.1080/14786419.2018.1437438 .

Bioactivity of Acanthus mollis – Contribution of benzoxazinoids and phenylpropanoids

Cruz, Maria Teresa, 2018. 2018. http://dx.doi.org/10.1016/j.jep.2018.09.013 . 10.1016/j.jep.2018.09.013 .

Nature and kinetics of redox imbalance triggered by respiratory and skin chemical sensitizers on the human monocytic cell line THP-1

Ferreira, Isabel; Silva, Ana; Martins, Joao Demetrio; Neves, Bruno Miguel; Cruz, Maria Teresa; Cruz, Maria Teresa, 2018. Redox Biology. 2018. https://publons.com/publon/16980300/ . 10.1016/J.REDOX.2018.02.002 . Redox Biology

Impact of different GMP media in the production of dendritic cells for next-generation cancer immunotherapy: Functional and metabolic characterization

Calmeiro, J.; Carrascal, M.; Gomes, C.; Falcao, A.; Serra, J.; Cruz, M. T.; Neves, B., 2018. Annals of Oncology. 2018. https://publons.com/publon/26807098/ . Annals of Oncology

New Insights into the Anti-Inflammatory and Antioxidant Properties of Nitrated Phospholipids

Melo, Tania; Marques, Sara S.; Ferreira, Isabel; Cruz, Maria Teresa; Domingues, Pedro; Segundo, Marcela A.; Marques Domingues, Maria Rosario; et al, 2018. Lipids. 117 - 131. 1. 53. 2018. https://publons.com/publon/3423064/ . 10.1002/LIPD.12007 . Lipids

Editorial: The Physiology of Inflammation—The Final Common Pathway to Disease

Mendes, A.F.; Cruz, M.T.; Gualillo, O.; Ferreira Mendes, Alexandrina; Teresa Cruz, Maria; Gualillo, Oreste; Mendes, Alexandrina Ferreira; Cruz, Maria Teresa, 2018. Frontiers in Physiology. 9. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070433771&partnerID=MN8TOARS . 10.3389/fphys.2018.01741 . Frontiers in Physiology

Antioxidant and anti-inflammatory activities of: Geranium robertianum L. decoctions

Catarino, M.D.; Silva, A.M.S.; Cruz, M.T.; Cardoso, S.M.; Marcelo D. Catarino; Artur M. S. Silva; Maria Teresa Cruz; Susana M. Cardoso, 2017. Food and Function. 3355 - 3365. 9. 8. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029740286&partnerID=MN8TOARS . 10.1039/c7fo00881c . Food and Function

Valorization of Lipids from Gracilaria sp through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity

da Costa, Elisabete; Melo, Tania; Moreira, Ana S. P.; Bernardo, Carina; Helguero, Luisa; Ferreira, Isabel; Cruz, Maria Teresa; et al, 2017. Marine Drugs. 3. 15. 2017. https://publons.com/publon/3423052/ . 10.3390/MD15030062 . Marine Drugs

Contact dermatitis: in pursuit of sensitizer’s molecular targets through proteomics

Guedes, S.; Neves, B.; Vitorino, R.; Domingues, R.; Cruz, M.T.; Domingues, P.; Guedes, Sofia; et al, 2017. Archives of Toxicology. 811 - 825. 2. 91. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964645560&partnerID=MN8TOARS . 10.1007/s00204-016-1714-y . Archives of Toxicology

Chemical Composition of Laurencia obtusa Extract and Isolation of a New C-15-Acetogenin

Esselin, Helene; Sutour, Sylvain; Liberal, Joana; Cruz, Maria Teresa; Salgueiro, Ligia; Siegler, Benjamin; Freuze, Ingrid; et al, 2017. Molecules. 5. 22. 2017. https://publons.com/publon/10621865/ . 10.3390/MOLECULES22050779 . Molecules

Dendritic cell-based immunotherapy: a basic review and recent advances

Constantino, Joao; Gomes, Celia; Falcao, Amilcar; Neves, Bruno Miguel; Cruz, Maria Teresa; Constantino, J.; Gomes, C.; et al, 2017. Immunologic Research. 798 - 810. 4. 65. 2017. https://publons.com/publon/9962888/ . 10.1007/S12026-017-8931-1 . Immunologic Research

Inflammasome in dendritic cells immunobiology: Implications to diseases and therapeutic strategies

Ferreira, I.; Liberal, J.; Martins, J.D.; Silva, A.; Neves, B.M.; Cruz, M.T., 2017. Current Drug Targets. 1003 - 1018. 9. 18. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85022193483&partnerID=MN8TOARS . 10.2174/1389450117666160921144830 . Current Drug Targets

Antioxidant, Anti-Inflammatory, and Analgesic Activities of Agrimonia eupatoria L. Infusion

Telmo N. Santos; Gustavo Costa; J. Pinto Ferreira; Joana Liberal; Vera Francisco; António Paranhos; Maria T. Cruz; et al, 2017. Evidence-Based Complementary and Alternative Medicine. 2017. 10.1155/2017/8309894 . Evidence-Based Complementary and Alternative Medicine

Assessment of safe bioactive doses of Foeniculum vulgare Mill. essential oil from Portugal

Cabral, C.; Miranda, M.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L., 2017. Natural Product Research. 2654 - 2659. 22. 31. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014579756&partnerID=MN8TOARS . 10.1080/14786419.2017.1292266 . Natural Product Research

Urtica spp.: Phenolic composition, safety, antioxidant and anti-inflammatory activities

Carvalho, Ana Rita; Costa, Gustavo; Figueirinha, Artur; Liberal, Joana; Prior, Joao A. V.; Lopes, Maria Celeste; Cruz, Maria Teresa; et al, 2017. Food Research International. 485 - 494. 99. 2017. https://publons.com/publon/10621866/ . 10.1016/J.FOODRES.2017.06.008 . Food Research International

Urolithins impair cell proliferation, arrest the cell cycle and induce apoptosis in UMUC3 bladder cancer cells

Liberal, Joana; Carmo, Analia; Gomes, Celia; Cruz, Maria Teresa; Batista, Maria Teresa; Liberal, J.; Carmo, A.; et al, 2017. Investigational New Drugs. 671 - 681. 6. 35. 2017. https://publons.com/publon/10621860/ . 10.1007/S10637-017-0483-7 . Investigational New Drugs

Lipophilic fraction of cultivated Bifurcaria bifurcata R. Ross: Detailed composition and in vitro prospection of current challenging bioactive properties

Santos, S.A.O.; Trindade, S.S.; Oliveira, C.S.D.; Parreira, P.; Rosa, D.; Duarte, M.F.; Ferreira, I.; et al, 2017. Marine Drugs. 11. 15. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85036574775&partnerID=MN8TOARS . 10.3390/md15110340 . Marine Drugs

In vitro macrophage nitric oxide production by Pterospartum tridentatum (L.) Willk. inflorescence polysaccharides

Martins, Vitor M. R.; Simoes, Joana; Ferreira, Isabel; Cruz, Maria Teresa; Rosario Domingues, M.; Coimbra, Manuel A.; Martins, V.M.R.; et al, 2017. Carbohydrate Polymers. 176 - 184. 157. 2017. https://publons.com/publon/953728/ . 10.1016/J.CARBPOL.2016.09.079 . Carbohydrate Polymers

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, D.J.; Abdelmohsen, K.; Abe, A.; Abedin, M.J.; Abeliovich, H.; Arozena, A.A.; Adachi, H.; et al, 2016. Autophagy. 1 - 222. 1. 12. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013763791&partnerID=MN8TOARS . 10.1080/15548627.2015.1100356 . Autophagy

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Klionsky, D.J.; Abdelmohsen, K.; Abe, A.; Abedin, M.J.; Abeliovich, H.; Arozena, A.A.; Adachi, H.; et al, 2016. Autophagy. 443 - 443. 2. 12. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85054826264&partnerID=MN8TOARS . 10.1080/15548627.2016.1147886 . Autophagy

New Claims for Wild Carrot (Daucus carota subsp carota) Essential Oil

Alves-Silva, Jorge M.; Zuzarte, Monica; Goncalves, Maria Jose; Cavaleiro, Carlos; Cruz, Maria Teresa; Cardoso, Susana M.; Salgueiro, Ligia, 2016. Evidence-Based Complementary and Alternative Medicine. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000371030000001&KeyUID=WOS:000371030000001 . 10.1155/2016/9045196 . Evidence-Based Complementary and Alternative Medicine

The Flavone Luteolin Inhibits Liver X Receptor Activation

Francisco, V.; Figueirinha, A.; Costa, G.; Liberal, J.; Ferreira, I.; Lopes, M.C.; García-Rodríguez, C.; et al, 2016. Journal of Natural Products. 1423 - 1428. 5. 79. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971463445&partnerID=MN8TOARS . 10.1021/acs.jnatprod.6b00146 . Journal of Natural Products

Chemical composition and biological activities of Artemisia judaica essential oil from southern desert of Jordan

Abu-Darwish, M.S.; Cabral, C.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Zulfiqar, A.; Khan, I.A.; et al, 2016. Journal of Ethnopharmacology. 161 - 168. 191. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84975894292&partnerID=MN8TOARS . 10.1016/j.jep.2016.06.023 . Journal of Ethnopharmacology

Ziziphora tenuior L. essential oil from Dana Biosphere Reserve (Southern Jordan); Chemical characterization and assessment of biological activities

Abu-Darwish, M.S.; Cabral, C.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Paoli, M.; Tomi, F.; et al, 2016. Journal of Ethnopharmacology. 963 - 970. 194. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85003967187&partnerID=MN8TOARS . 10.1016/j.jep.2016.10.076 . Journal of Ethnopharmacology

Antitumor dendritic cell-based vaccines: lessons from 20 years of clinical trials and future perspectives.

Constantino J; Gomes C; Falcão A; Cruz MT; Neves BM, 2016. 2016. http://europepmc.org/abstract/med/26297944 . 10.1016/j.trsl.2015.07.008 .

Adenosine diphosphate involvement in THP-1 maturation triggered by the contact allergen 1-fluoro-2,4-dinitrobenzene

Martins, J. D.; Silva, A.; Ferreira, I.; Goncalo, M.; Custodio, J. B. A.; Lopes, M. C.; Domingues, M. R. M.; et al, 2016. Toxicology Research. 1512 - 1521. 6. 5. 2016. https://publons.com/publon/9962889/ . 10.1039/C6TX00240D . Toxicology Research

PROPOLIS ACTION IN CYTOKINE PRODUCTION BY RETINOIC ACID-STIMULATED HUMAN MONOCYTES

Conte, F. L.; Santiago, K. B.; Conti, B. J.; Cardoso, E. O.; Oliveira, L. P. G.; Cruz, M. T.; Sforcin, J. M., 2016. Cytokine. 2016. https://publons.com/publon/10621854/ . Cytokine

IMMUNOMODULATORY ACTION OF PROPOLIS ON MAGE-1-INDUCED-CYTOKINE PRODUCTION BY HUMAN MONOCYTES

Santiago, K. B.; Conti, B. J.; Conte, F. L.; Oliveira, L. P. G.; Cardoso, E. O.; Cruz, M. T.; Sforcin, J. M., 2016. Cytokine. 2016. https://publons.com/publon/10621873/ . Cytokine

BRAZILIAN PROPOLIS MODULATES CYTOKINE PRODUCTION BY LPS-ACTIVATED HUMAN MONOCYTES

Conti, B. J.; Santiago, K. B.; Conte, F. L.; Cardoso, E. O.; Oliveira, L. P. G.; Cruz, M. T.; Sforcin, J. M., 2016. Cytokine. 2016. https://publons.com/publon/10621855/ . Cytokine

Phospholipidomic Profile Variation on THP-1 Cells Exposed to Skin or Respiratory Sensitizers and Respiratory Irriant

Martins, Joao D.; Maciel, Elisabeta A.; Silva, Ana; Ferreira, Isabel; Ricardo, Fernando; Domingues, Pedro; Neves, Bruno M.; et al, 2016. Journal of Cellular Physiology. S235 - S236. 2. 238. 2016. https://publons.com/publon/5481459/ . 10.1002/JCP.25365 . Journal of Cellular Physiology

Immunomodulatory/inflammatory effects of geopropolis produced by Melipona fasciculata Smith in combination with doxorubicin on THP-1 cells

Lucas Pires Garcia Oliveira; Fernanda Lopes Conte; Eliza de Oliveira Cardoso; Bruno José Conti; Karina Basso Santiago; Marjorie de Assis Golim; Maria Teresa Cruz; et al, 2016. Journal of Pharmacy and Pharmacology. 2016. http://dx.doi.org/10.1111/jphp.12649 . 10.1111/jphp.12649 . Journal of Pharmacy and Pharmacology

Ridolfia segetum (L.) Moris (Apiaceae) from Portugal: A source of safe antioxidant and anti-inflammatory essential oil

Cabral, C.; Pocas, J.; Goncalves, M. J.; Cavaleiro, C.; Cruz, M. T.; Salgueiro, L.; Cruz, Maria Teresa, 2015. Industrial Crops and Products. 56 - 61. 65. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000349430000008&KeyUID=WOS:000349430000008 . 10.1016/j.indcrop.2014.11.041 . Industrial Crops and Products

Bioactivity and safety profile of Daucus carota subsp. maximus essential oil

Cruz, Maria Teresa; J. Valente; R. Resende; M. Zuzarte; M.J. Gonçalves; M.C. Lopes; C. Cavaleiro; et al, 2015. Industrial Crops and Products. 218 - 224. 77. 2015. https://doi.org/10.1016%2Fj.indcrop.2015.08.037 . doi:10.1016/j.indcrop.2015.08.037 . Industrial Crops and Products

Daucus carota subsp. gummifer essential oil as a natural source of antifungal and anti-inflammatory drugs

Cruz, Maria Teresa; Valente, J.; Zuzarte, M.; Resende, R.; Goncalves, M. J.; Cavaleiro, C.; Pereira, C. F.; Cruz, M. T.; Salgueiro, L., 2015. Industrial Crops and Products. 361 - 366. 65. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000349430000046&KeyUID=WOS:000349430000046 . doi:10.1016/j.indcrop.2014.11.014 . Industrial Crops and Products

Myrtus communis L. as source of a bioactive and safe essential oil.

Bouzabata A; Cabral C; Gonçalves MJ; Cruz MT; Bighelli A; Cavaleiro C; Casanova J; Tomi F; Salgueiro L, 2015. 2015. http://europepmc.org/abstract/med/25446467 . 10.1016/j.fct.2014.11.009 .

Oxidative stress-dependent activation of the eIF2 alpha-ATF4 unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner (vol 77, pg 217, 2014)

Luis, Andreia; Martins, Joao Demetrio; Silva, Ana; Ferreira, Isabel; Cruz, Maria Teresa; Neves, Bruno Miguel, 2015. Free Radical Biology and Medicine. 203 - 203. 82. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000352823700018&KeyUID=WOS:000352823700018 . 10.1016/j.freeradbiomed.2015.01.009 . Free Radical Biology and Medicine

Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells.

Gonçalo M; Martins J; Silva A; Neves B; Figueiredo A; Cruz T; Lopes C, 2015. 2015. http://europepmc.org/abstract/med/25091725 . 10.1002/jat.3033 .

Autophagy and inflammasome interplay.

Martins JD; Liberal J; Silva A; Ferreira I; Neves BM; Cruz MT, 2015. 2015. http://europepmc.org/abstract/med/25757059 . 10.1089/dna.2014.2752 .

Cymbopogon citratus industrial waste as a potential source of bioactive compounds.

Tavares F; Costa G; Francisco V; Liberal J; Figueirinha A; Lopes MC; Cruz MT; Batista MT, 2015. 2015. http://europepmc.org/abstract/med/25389117 . 10.1002/jsfa.6999 .

Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory doses.

Abu-Darwish MS; Cabral C; Gonçalves MJ; Cavaleiro C; Cruz MT; Efferth T; Salgueiro L, 2015. 2015. http://europepmc.org/abstract/med/26277492 . 10.1016/j.jep.2015.08.005 .

Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves

Cruz, Maria Teresa, 2015. 2015. http://dx.doi.org/10.1016/j.arabjc.2015.11.014 . 10.1016/j.arabjc.2015.11.014 .

Chemical composition, anti-inflammatory activity and cytotoxicity of Thymus zygis L. subsp. sylvestris (Hoffmanns. & Link) Cout. essential oil and its main compounds

Cruz, Maria Teresa, 2015. 2015. http://dx.doi.org/10.1016/j.arabjc.2015.08.026 . 10.1016/j.arabjc.2015.08.026 .

Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH

Cruz, Maria Teresa, 2014. Arch Biochem Biophys. 2014. 10.1016/j.abb.2014.02.002 . Arch Biochem Biophys

Chemical characterization and anti-inflammatory activity of luteolin glycosides isolated from lemongrass

Cruz, Maria Teresa; Francisco, Vera; Figueirinha, Artur; Costa, Gustavo; Liberal, Joana; Lopes, Maria Celeste; Garcia-Rodriguez, Carmen; et al, 2014. Journal of Functional Foods. 436 - 443. 10. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342034200047&KeyUID=WOS:000342034200047 . doi:10.1016/j.jff.2014.07.003 . Journal of Functional Foods

Neurotensin decreases the proinflammatory status of human skin fibroblasts and increases epidermal growth factor expression.

Pereira da Silva L; Miguel Neves B; Moura L; Cruz MT; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/25180119 . 10.1155/2014/248240 .

The effect of neurotensin in human keratinocytes--implication on impaired wound healing in diabetes.

Moura LI; Cruz MT; Carvalho E, 2014. 2014. http://europepmc.org/abstract/med/24198343 . 10.1177/1535370213510665 .

Drugs inducing T-cell mediated cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells.

Gonçalo M; Martins J; Silva A; Neves B; Cruz T; Lopes C, 2014. 2014. http://europepmc.org/abstract/PMC/PMC4128176 . 10.1186/2045-7022-4-S3-P50 .

Antifungal and anti-inflammatory claims for wild carrot essential oil

Valente, J.; Resende, R.; Zuzarte, M.; Goncalves, M. J.; Lopes, M. C.; Cavaleiro, C.; Pereira, C.; Salgueiro, L.; Cruz, M. T., 2014. Planta Medica. 1454 - 1454. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400318&KeyUID=WOS:000345550400318 . 10.1055/S-0034-1394792 . Planta Medica

Anti-inflammatory potential of the essential oil of the Iberian endemism Thymus carnosus

Alves, M.; Zuzarte, M.; Goncalves, M. J.; Cruz, M. T.; Cavaleiro, C.; Salgueiro, L., 2014. Planta Medica. 1448 - 1448. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400299&KeyUID=WOS:000345550400299 . 10.1055/S-0034-1394773 . Planta Medica

Anti-inflammatory effects of Thymus zygis subsp sylvestris essential oil in LPS-stimulated macrophages and microglia cells

Rodrigues, V.; Cabral, C.; Evora, L.; Ferreira, I.; Pereira, C.; Cavaleiro, C.; Cruz, M. T.; Salgueiro, L., 2014. Planta Medica. 1436 - 1437. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400263&KeyUID=WOS:000345550400263 . Planta Medica

Bioactive polyphenols from cork industry by-products

Ferreira, I. V.; Liberal, J.; Santos, T.; Silva, S.; Cruz, M. T.; Batista, M. T., 2014. Planta Medica. 1506 - 1506. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400477&KeyUID=WOS:000345550400477 . 10.1055/S-0034-1394951 . Planta Medica

Assessment of the properties of the essential oil from Ridolfia segetum Moris (Portugal) on cancer cell viability

Pocas, J.; Lemos, M.; Cabral, C.; Cavaleiro, C.; Cruz, M. T.; Salgueiro, L.; Pires, I., 2014. Planta Medica. 1425 - 1426. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400227&KeyUID=WOS:000345550400227 . 10.1055/S-0034-1394701 . Planta Medica

iTRAQ-based proteomic analysis of ellagitannins-enriched fraction from Fragaria vesca leaves on HepG2 cells

Liberal, J.; Costa, G.; Marques, C.; Girao, H.; Vitorino, R.; Domingues, R.; Domingues, P.; Cruz, M. T.; Batista, M. T., 2014. Planta Medica. 1438 - 1438. 16. 80. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345550400268&KeyUID=WOS:000345550400268 . 10.1055/S-0034-1394742 . Planta Medica

Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells.

Silva A; Nunes C; Martins J; Dinis TC; Lopes C; Neves B; Cruz T, 2014. 2014. http://europepmc.org/abstract/med/24742817 . 10.1016/j.freeradbiomed.2014.04.005 .

Oxidative stress-dependent activation of the eIF2a-ATF4 UPR branch by skin sensitizer DNFB modulates dendritic-like cell maturation and inflammatory status in a biphasic manner.

Luís A; Martins JD; Silva A; Ferreira I; Cruz MT; Neves BM, 2014. 2014. http://europepmc.org/abstract/med/25236743 .

Bioactivity of Fragaria vesca leaves through inflammation, proteasome and autophagy modulation.

Liberal J; Francisco V; Costa G; Figueirinha A; Amaral MT; Marques C; Girão H; et al, 2014. 2014. http://europepmc.org/abstract/med/25305515 . 10.1016/j.jep.2014.09.043 .

NO radical scavenging and iNOS expression inhibition by Cytisus multiflorus

Saraiva, S. C.; Pereira, O. R.; Liberal, J.; Batista, M. T.; Cruz, M. T.; Cardoso, S. M., 2013. European Journal of Clinical Investigation. 62 - 62. 43. 2013. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000317141000180&KeyUID=WOS:000317141000180 . European Journal of Clinical Investigation

Prospective phospholipid markers for skin sensitization prediction in keratinocytes: A phospholipidomic approach

Santinha, D.R.; Luísa Dória, M.; Neves, B.M.; Maciel, E.A.; Martins, J.; Helguero, L.; Domingues, P.; Teresa Cruz, M.; Rosário Domingues, M., 2013. Archives of Biochemistry and Biophysics. 33 - 41. 1-2. 533. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875667120&partnerID=MN8TOARS . 10.1016/j.abb.2013.02.012 . Archives of Biochemistry and Biophysics

Ellagitannin-enriched fraction from Fragaria vesca leaves induces G2/M cell cycle arrest in the human hepatocellular carcinoma cell line HepG2

Liberal, J. T.; Costa, G.; Carmo, A.; Marques, C.; Cruz, M.; Batista, M., 2013. Planta Medica. 2013. https://publons.com/publon/26807099/ . 10.1055/S-0033-1352234 . Planta Medica

Leishmania-infected MHC class II<sup>high</sup> dendritic cells polarize CD4<sup>+</sup> T cells toward a nonprotective T-bet<sup>+</sup> IFN-¿<sup>+</sup> IL-10<sup>+</sup> phenotype

Resende, M.; Moreira, D.; Augusto, J.; Cunha, J.; Neves, B.; Cruz, M.T.; Estaquier, J.; Cordeiro-da-Silva, A.; Silvestre, R., 2013. Journal of Immunology. 262 - 273. 1. 191. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879675210&partnerID=MN8TOARS . 10.4049/jimmunol.1203518 . Journal of Immunology

Antifungal, antioxidant and anti-inflammatory activities of Oenanthe crocata L. essential oil

Cruz, Maria Teresa, 2013. Food Chem Toxicol. 2013. 10.1016/j.fct.2013.08.083 . Food Chem Toxicol

New compounds, chemical composition, antifungal activity and cytotoxicity of the essential oil from Myrtus nivellei Batt. &amp; Trab.; An endemic species of Central Sahara

Bouzabata, A.; Bazzali, O.; Cabral, C.; Gonçalves, M.J.; Cruz, M.T.; Bighelli, A.; Cavaleiro, C.; et al, 2013. Journal of Ethnopharmacology. 613 - 620. 3. 149. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884415386&partnerID=MN8TOARS . 10.1016/j.jep.2013.06.054 . Journal of Ethnopharmacology

Margotia gummifera essential oil as a source of anti-inflammatory drugs

Valente, J.; Zuzarte, M.; Liberal, J.; Gonçalves, M.J.; Lopes, M.C.; Cavaleiro, C.; Cruz, M.T.; Salgueiro, L., 2013. Industrial Crops and Products. 86 - 91. 47. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875590010&partnerID=MN8TOARS . 10.1016/j.indcrop.2013.02.036 . Industrial Crops and Products

Development of an in vitro dendritic cell-based test for skin sensitizer identification

Neves, B.M.; Rosa, S.C.; Martins, J.D.; Silva, A.; Goncìalo, M.; Lopes, M.C.; Cruz, M.T., 2013. Chemical Research in Toxicology. 368 - 378. 3. 26. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875168719&partnerID=MN8TOARS . 10.1021/tx300472d . Chemical Research in Toxicology

Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions

Moura, L.I.F.; Silva, L.; Leal, E.C.; Tellechea, A.; Cruz, M.T.; Carvalho, E., 2013. BioMed Research International. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884259661&partnerID=MN8TOARS . 10.1155/2013/941764 . BioMed Research International

Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: Potential benefits for wound healing

Moura, J.; Da Silva, L.; Cruz, M.T.; Carvalho, E., 2013. Archives of Dermatological Research. 557 - 569. 7. 305. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883240109&partnerID=MN8TOARS . 10.1007/s00403-013-1381-2 . Archives of Dermatological Research

Essential oil of common sage (Salvia officinalis L.) from Jordan: Assessment of safety in mammalian cells and its antifungal and anti-inflammatory potential

Abu-Darwish, M.S.; Cabral, C.; Ferreira, I.V.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Al-Bdour, T.H.; Salgueiro, L., 2013. BioMed Research International. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886511600&partnerID=MN8TOARS . 10.1155/2013/538940 . BioMed Research International

Anti-inflammatory activity of Cymbopogon citratus leaves infusion via proteasome and nuclear factor-¿B pathway inhibition: contribution of chlorogenic acid.

Francisco V; Costa G; Figueirinha A; Marques C; Pereira P; Miguel Neves B; Celeste Lopes M; et al, 2013. 2013. http://europepmc.org/abstract/med/23583902 . 10.1016/j.jep.2013.03.077 .

Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-¿B and MAPK activation in macrophages

Búfalo, Michelle Cristiane; Ferreira, Isabel; Costa, Gustavo; Francisco, Vera; Liberal, Joana; Cruz, Maria Teresa; Lopes, Maria Celeste; et al, 2013. Journal of Ethnopharmacology. 84 - 92. 1. 149. 2013. http://hdl.handle.net/10316/27433 . 10.1016/j.jep.2013.06.004 . Journal of Ethnopharmacology

Cymbopogon citratus industrial waste as source of an anti-inflammatory drug

Tavares, F.; Costa, G.; Francisco, V; Cruz, M.; Batista, M., 2013. Planta Medica. 2013. https://publons.com/publon/26807100/ . 10.1055/S-0033-1352214 . Planta Medica

Antifungal and anti-inflammatory potential of Lavandula stoechas and Thymus herba-barona essential oils

Zuzarte, M.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Benzarti, A.; Marongiu, B.; Maxia, A.; Piras, A.; Salgueiro, L., 2013. Industrial Crops and Products. 97 - 103. 44. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870480491&partnerID=MN8TOARS . 10.1016/j.indcrop.2012.11.002 . Industrial Crops and Products

Otanthus maritimus (L.) Hoffmanns. &amp; Link as a source of a bioactive and fragrant oil

Cabral, C.; Cavaleiro, C.; Gonçalves, M.J.; Cruz, M.T.; Lopes, M.C.; Salgueiro, L., 2013. Industrial Crops and Products. 484 - 489. 1. 43. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865287737&partnerID=MN8TOARS . 10.1016/j.indcrop.2012.07.057 . Industrial Crops and Products

Intracellular signaling pathways modulated by phenolic compounds: Application for new anti-inflammatory drugs discovery

Costa, G.; Francisco, V.; Lopes, M.C.; Cruz, M.T.; Batista, M.T.; Costa G; Francisco V; et al, 2012. Current Medicinal Chemistry. 2876 - 2900. 18. 19. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861917656&partnerID=MN8TOARS . 10.2174/092986712800672049 . Current Medicinal Chemistry

Antioxidant activity of polyphenol-enriched fractions from Agrimonia Eupatoria L. infusion

Costa, G.; Liberal, J.; Francisco, V.; Paranhos, A.; Cruz, M. T.; Lopes, M. C.; Batista, M. T., 2012. Planta Medica. 1074 - 1074. 11. 78. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307042800181&KeyUID=WOS:000307042800181 . 10.1055/S-0032-1320366 . Planta Medica

Anti-inflammatory potential of Lavandula viridis esential oil

Zuzarte, M.; Goncalves, M. J.; Francisco, V.; Neves, B.; Liberal, J.; Cavaleiro, C.; Canhoto, J.; Cruz, T.; Salgueiro, L., 2012. Planta Medica. 1192 - 1192. 11. 78. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307042801149&KeyUID=WOS:000307042801149 . 10.1055/S-0032-1320898 . Planta Medica

Profiling changes triggered during maturation of dendritic cells: A lipidomic approach

Santinha, D.R.; Marques, D.R.; Maciel, E.A.; Simões, C.S.O.; Rosa, S.; Neves, B.M.; Macedo, B.; et al, 2012. Analytical and Bioanalytical Chemistry. 457 - 471. 2. 403. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861231971&partnerID=MN8TOARS . 10.1007/s00216-012-5843-8 . Analytical and Bioanalytical Chemistry

EPPUR SI MUOVE? DISTOPIAS DO ESPECTADOR

Godinho, Jacinto; Cruz, Maria Teresa, 2012. 43/44. 2012. published

Composition, antifungal activity and cytotoxicity of the essential oils of Seseli tortuosum L. and Seseli montanum subsp. peixotoanum (Samp.) M. Laínz from Portugal

Gonçalves, M.J.; Tavares, A.C.; Cavaleiro, C.; Cruz, M.T.; Lopes, M.C.; Canhoto, J.; Salgueiro, L., 2012. Industrial Crops and Products. 204 - 209. 1. 39. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84858174507&partnerID=MN8TOARS . 10.1016/j.indcrop.2012.02.025 . Industrial Crops and Products

Essential oil of juniperus communis subsp. alpina (Suter) Celak needles: Chemical composition, antifungal activity and cytotoxicity

Cabral, C.; Francisco, V.; Cavaleiro, C.; Gonçalves, M.J.; Cruz, M.T.; Sales, F.; Batista, M.T.; Salgueiro, L., 2012. Phytotherapy Research. 1352 - 1357. 9. 26. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866116136&partnerID=MN8TOARS . 10.1002/ptr.3730 . Phytotherapy Research

Composition and biological activity of the essential oil from Thapsia minor, a new source of geranyl acetate

Gonçalves, M.J.; Cruz, M.T.; Tavares, A.C.; Cavaleiro, C.; Lopes, M.C.; Canhoto, J.; Salgueiro, L., 2012. Industrial Crops and Products. 166 - 171. 1. 35. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051950044&partnerID=MN8TOARS . 10.1016/j.indcrop.2011.06.030 . Industrial Crops and Products

Role of the extra-cellular danger signal adenosine-5 '-triphosphate on the 1-fluoro-2,4-dinitrobenzene-induced maturation of THP-1 cells

Martins, J. D.; Neves, B. M.; Goncalo, M.; Lopes, M. C.; Domingues, M. R.; Cruz, M. T., 2012. Journal of Investigative Dermatology. S116 - S116. 132. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307814000661&KeyUID=WOS:000307814000661 . Journal of Investigative Dermatology

Targeting proteasome and autophagy with Fragaria Vesca L

Liberal, J.; Francisco, V.; Amaral, M. T.; Marques, C.; Lopes, M. C.; Cruz, M. T.; Batista, M. T., 2012. Planta Medica. 1073 - 1074. 11. 78. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307042800180&KeyUID=WOS:000307042800180 . 10.1055/S-0032-1320365 . Planta Medica

Immunostimulant activity of Uncaria Tomentosa and its tannins

Francisco, V.; Liberal, J.; Ferreira, J.; Costa, G.; Lopes, M. C.; Garcia-Rodriguez, C.; Cruz, M. T.; Batista, M. T., 2012. Planta Medica. 1074 - 1074. 11. 78. 2012. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000307042800182&KeyUID=WOS:000307042800182 . 10.1055/S-0032-1320367 . Planta Medica

Lavandula luisieri essential oil as a source of antifungal drugs

Zuzarte, M.; Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Canhoto, J.; Vaz, S.; Pinto, E.; Salgueiro, L., 2012. Food Chemistry. 1505 - 1510. 3. 135. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84865720631&partnerID=MN8TOARS . 10.1016/j.foodchem.2012.05.090 . Food Chemistry

Studies on severe adverse drug reactions from allopurinol

2012. Journal of Investigative Dermatology. 2012. https://publons.com/wos-op/publon/10621856/ . Journal of Investigative Dermatology

Modulation of Sphingosine-1-Receptors expression by LPS and contact allergen PPD

Rosa, Susana; Neves, Bruno Miguel; Goncalo, Margarida; Domingues, Maria Rosario; Santinha, Deolinda; Macedo, Barbara; Lopes, Maria Celeste; Cruz, Maria Teresa, 2011. Journal of Investigative Dermatology. S90 - S90. 131. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294361300535&KeyUID=WOS:000294361300535 . Journal of Investigative Dermatology

Phytochemical and biological characterization of Agrimonia eupatoria L.: an approach to structure-activity

Costa, G.; Francisco, V.; Liberal, J.; Figueirinha, A.; Cruz, T.; Figueiredo, I.; Lopes, C.; Batista, T., 2011. Planta Medica. 1420 - 1421. 12. 77. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294139000766&KeyUID=WOS:000294139000766 . 10.1055/S-0031-1282843 . Planta Medica

Anti-inflammatory properties of polyphenols from Cymbopogon citratus by inhibition of NF-kappa B pathway

Francisco, V.; Figueirinha, A.; Costa, G.; Lopes, M. C.; Garcia-Rodriguez, C.; Cruz, M. T.; Batista, M. T., 2011. Planta Medica. 1419 - 1420. 12. 77. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294139000762&KeyUID=WOS:000294139000762 . Planta Medica

Neurotensin downregulates the pro-inflammatory properties of skin dendritic cells and increases epidermal growth factor expression

da Silva, L.; Neves, B.M.; Moura, L.; Cruz, M.T.; Carvalho, E.; Neves, B. M.; Cruz, M. T., 2011. Biochimica et Biophysica Acta - Molecular Cell Research. 1863 - 1871. 10. 1813. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80051782996&partnerID=MN8TOARS . 10.1016/j.bbamcr.2011.06.018 . Biochimica et Biophysica Acta - Molecular Cell Research

Signal transduction profile of chemical sensitisers in dendritic cells: An endpoint to be included in a cell-based in vitro alternative approach to hazard identification?

Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.; Cruz, M.T., 2011. Toxicology and Applied Pharmacology. 87 - 95. 2. 250. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650559757&partnerID=MN8TOARS . 10.1016/j.taap.2010.10.003 . Toxicology and Applied Pharmacology

Cymbopogon citratus as source of new and safe anti-inflammatory drugs: Bio-guided assay using lipopolysaccharide-stimulated macrophages

Francisco, Vera; Figueirinha, Artur; Neves, Bruno Miguel; García-Rodríguez, Carmen; Lopes, Maria Celeste; Cruz, Maria Teresa; Batista, Maria Teresa; et al, 2011. Journal of Ethnopharmacology. 818 - 827. 2. 133. 2011. http://hdl.handle.net/10316/18004 . 10.1016/j.jep.2010.11.018 . Journal of Ethnopharmacology

An in vitro cell test for skin sensitizers prediction based on the analysis and integration of gene expression and signaling pathways activation

Neves, Bruno; Rosa, Susana; Martins, Joao; Goncalo, Margarida; Lopes, Maria Celeste; Cruz, Maria Teresa, 2011. Journal of Investigative Dermatology. S91 - S91. 131. 2011. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294361300538&KeyUID=WOS:000294361300538 . Journal of Investigative Dermatology

Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing

Da Silva, L.; Carvalho, E.; Cruz, M.T., 2010. Expert Opinion on Biological Therapy. 1427 - 1439. 10. 10. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956664657&partnerID=MN8TOARS . 10.1517/14712598.2010.515207 . Expert Opinion on Biological Therapy

Essential oils from Distichoselinum tenuifolium: Chemical composition, cytotoxicity, antifungal and anti-inflammatory properties

Tavares, A.C.; Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Lopes, M.C.; Canhoto, J.; Salgueiro, L.R.; et al, 2010. Journal of Ethnopharmacology. 593 - 598. 3. 130. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954954559&partnerID=MN8TOARS . 10.1016/j.jep.2010.05.054 . Journal of Ethnopharmacology

Chemical, antifungal and cytotoxic evaluation of the essential oil of Thymus zygis subsp. sylvestris

Gonçalves, M.J.; Cruz, M.T.; Cavaleiro, C.; Lopes, M.C.; Salgueiro, L., 2010. Industrial Crops and Products. 70 - 75. 1. 32. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954864678&partnerID=MN8TOARS . 10.1016/j.indcrop.2010.03.005 . Industrial Crops and Products

Activation of phosphatidylinositol 3-kinase/akt and impairment of nuclear factor-¿B: Molecular mechanisms behind the arrested maturation/activation state of leishmania infantum-infected dendritic cells

Neves, B.M.; Silvestre, R.; Resende, M.; Ouaissi, A.; Cunha, J.; Tavares, J.; Loureiro, I.; et al, 2010. American Journal of Pathology. 2898 - 2911. 6. 177. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650195216&partnerID=MN8TOARS . 10.2353/ajpath.2010.100367 . American Journal of Pathology

Anti-inflammatory activity of cymbopogon citratus leaf infusion in lipopolysaccharide-stimulated dendritic cells: Contribution of the polyphenols

Figueirinha, A.; Cruz, M.T.; Francisco, V.; Lopes, M.C.; Batista, M.T., 2010. Journal of Medicinal Food. 681 - 690. 3. 13. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77953730391&partnerID=MN8TOARS . 10.1089/jmf.2009.0115 . Journal of Medicinal Food

Effect of lipopolysaccharide, skin sensitizers and irritants on thioredoxin-1 expression in dendritic cells: Relevance of different signalling pathways

Francisco, V.; Neves, B.M.; Cruz, M.T.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2010. Archives of Dermatological Research. 271 - 282. 4. 302. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952180893&partnerID=MN8TOARS . 10.1007/s00403-009-0993-z . Archives of Dermatological Research

CXCL12/CXCR4 promotes motility and proliferation of glioma cells

do Carmo, Analia; Patricio, Ines; Cruz, Maria T.; Carvalheiro, Helena; Oliveira, Catarina R.; Lopes, Maria C.; do Carmo A; et al, 2010. Cancer Biology & Therapy. 56 - 65. 1. 9. 2010. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000274578800011&KeyUID=WOS:000274578800011 . 10.4161/cbt.9.1.10342 . Cancer Biology & Therapy

Potential antioxidant and anti-inflammatory properties in Teucrium salviastrum Schreb

Cabral, C.; Francisco, V; Cruz, M.; Lopes, M.; Salgueiro, L.; Sales, F.; Batista, M., 2010. Planta Medica. 2010. https://publons.com/publon/7273471/ . 10.1055/S-0030-1264535 . Planta Medica

Polyphenols from Cymbopogon citratus inhibit iNOS expression and NO production - a promising source of new anti-inflammatory drugs

Francisco, V; Figueirinha, A.; Neves, B.; Garcia-Rodriguez, C.; Lopes, M.; Cruz, M.; Batista, M., 2010. Planta Medica. 2010. https://publons.com/publon/21604165/ . Planta Medica

Differential roles of PI3-Kinase, MAPKs and NF-¿B on the manipulation of dendritic cell T<inf>h</inf>1/T<inf>h</inf>2 cytokine/chemokine polarizing profile

Neves, B.M.; Cruz, M.T.; Francisco, V.; Garcia-Rodriguez, C.; Silvestre, R.; Cordeiro-da-Silva, A.; Dinis, A.M.; et al, 2009. Molecular Immunology. 2481 - 2492. 13. 46. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-67650397827&partnerID=MN8TOARS . 10.1016/j.molimm.2009.05.021 . Molecular Immunology

Inhibition of LPS-induced nuclear factor NF-kappa B activation by Cymbopogon citratus leaves in macrophages: a strategy to develop new anti-inflammatory drugs

Francisco, V.; Cruz, T.; Figueirinha, A.; Neves, B.; Lopes, C.; Batista, T., 2009. Planta Medica. 942 - 942. 9. 75. 2009. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000268806600239&KeyUID=WOS:000268806600239 . Planta Medica

CXCL12/CXCR4 MODULATES GLIOMA CELL SURVIVAL AND MOTILITY

Carmo, Analia; Carvalheiro, Helena; Cruz, Maria Teresa; Lopes, Maria Celeste, 2009. Iubmb Life. 326 - 326. 3. 61. 2009. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000264089500174&KeyUID=WOS:000264089500174 . Iubmb Life

Essential oil of Daucus carota subsp. halophilus: Composition, antifungal activity and cytotoxicity

Tavares, A.C.; Gonçalves, M.J.; Cavaleiro, C.; Cruz, M.T.; Lopes, M.C.; Canhoto, J.; Salgueiro, L.R.; et al, 2008. Journal of Ethnopharmacology. 129 - 134. 1. 119. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-49349115295&partnerID=MN8TOARS . 10.1016/j.jep.2008.06.012 . Journal of Ethnopharmacology

Differential modulation of CXCR4 and CD40 protein levels by skin sensitizers and irritants in the FSDC cell line

Neves, B.M.; Cruz, M.T.; Francisco, V.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C.; et al, 2008. Toxicology Letters. 74 - 82. 1. 177. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-39549123001&partnerID=MN8TOARS . 10.1016/j.toxlet.2007.12.006 . Toxicology Letters

CXCR4 expression mediates the survival and proliferation of glioma cells

Carmo, A.; Patrlcio, M. I.; Amaro, P.; Cruz, M. T.; Lopes, M. C., 2008. Ejc Supplements. 20 - 20. 9. 6. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000257919000078&KeyUID=WOS:000257919000078 . 10.1016/s1359-6349(08)71252-7 . Ejc Supplements

Effect of skin sensitizers on inducible nitric oxide synthase expression and nitric oxide production in skin dendritic cells: Role of different immunosuppressive drugs

Cruz, M.T.; Neves, B.M.; Gonçalo, M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2007. Immunopharmacology and Immunotoxicology. 225 - 241. 2. 29. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548553284&partnerID=MN8TOARS . 10.1080/08923970701512304 . Immunopharmacology and Immunotoxicology

Differential CXCR4 expression induced by skin sensitizers or irritants in dendritic cell models

Neves, B.; Cruz, M. T.; Goncalo, M.; Figueiredo, A.; Duarte, C. B.; Lopes, M. C., 2007. Journal of Investigative Dermatology. S5 - S5. 127. 2007. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000249933400026&KeyUID=WOS:000249933400026 . Journal of Investigative Dermatology

The sensitizers nickel sulfate and 2,4-dinitrofluorobenzene increase CD40 and IL-12 receptor expression in a fetal skin dendritic cell line

Vital, A.L.; Gonçalo, M.; Cruz, M.T.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2005. Bioscience Reports. 191 - 202. 3. 24. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-23944504971&partnerID=MN8TOARS . 10.1007/s10540-005-2580-7 . Bioscience Reports

Contact sensitizers downregulate the expression of the chemokine receptors CCR6 and CXCR4 in a skin dendritic cell line

Cruz, M.T.; Gonçalo, M.; Paiva, A.; Morgado, J.M.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2005. Archives of Dermatological Research. 43 - 47. 1. 297. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-25644435637&partnerID=MN8TOARS . 10.1007/s00403-005-0574-8 . Archives of Dermatological Research

The Sensitizers Nickel Sulfate and 2,4-dinitrofluorobenzene Increase CD40 and IL-12 Receptor Expression in a Fetal Skin Dendritic Cell Line

Vital, Ana Luísa; Gonçalo, Margarida; Cruz, Maria Teresa; Figueiredo, Américo; Duarte, Carlos B.; Lopes, Maria Celeste, 2004. 2004. http://hdl.handle.net/10316/7941 .

The sensitizers nickel sulfate and 2,4-dinitrofluorobenzene induce the expression of CD40 and IL-12 receptor in a fetal skin dendritic cell line, whereas 2,4-dichloronitrobenzene has no effect.

Vital, A. L.; Gonçalo, Margarida; Cruz, Maria Teresa; Figueiredo, Américo; Duarte, Carlos B.; Lopes, Maria Celeste, 2004. Bioscience Reports . 191 - 202. 24. 2004. published Bioscience Reports

The contact sensitizer Nickel sulphate activates the transcription factor NF-kB and AP-1 and induces the expression of nitric oxide in a skin dendritic cell line

Cruz, Maria Teresa; Gonçalo, Margarida; Américo Figueiredo; Carvalho A. P.; Duarte, Carlos B.; Lopes, Maria Celeste, 2004. Experimental Dermatol . 18 - 26. 13. 2004. published Experimental Dermatol

Contact sensitizer nickel sulfate activates the transcription factors NF-kB and AP-1 and increases the expression of nitric oxide synthase in a skin dendritic cell line

Cruz, M.T.; Gonçalo, M.; Figueiredo, A.; Carvalho, A.P.; Duarte, C.B.; Lopes, M.C., 2004. Experimental Dermatology. 18 - 26. 1. 13. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-0842308107&partnerID=MN8TOARS . 10.1111/j.0906-6705.2004.00105.x . Experimental Dermatology

Dexamethasone prevents granulocyte-macrophage colony-stimulating factor-induced nuclear factor-¿B activation, inducible nitric oxide synthase expression and nitric oxide production in a skin dendritic cell line

Vital, A.L.; Gonçalo, M.; Cruz, M.T.; Figueiredo, A.; Duarte, C.B.; Lopes, M.C., 2003. Mediators of Inflammation. 71 - 78. 2. 12. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0038466135&partnerID=MN8TOARS . 10.1080/0962935031000097673 . Mediators of Inflammation

The sensitizer 2,4 dinitrofluorbenzene induces cell death in a skin dendritic cell line by activating caspase 3

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Figueiredo, Américo; Carvalho A. P.; Lopes, Maria Celeste, 2003. International Journal of Toxicology . 43 - 48. 22. 2003. published International Journal of Toxicology

The sensitizer 2,4-dinitrofluorobenzene activates caspase-3 and induces cell death in a skin dendritic cell line

Cruz, M. T.; Duarte, C. B.; Goncalo, M.; Figueiredo, A.; Carvalho, A. P.; Lopes, M. C.; Cruz, M.T.; et al, 2003. International Journal of Toxicology. 43 - 48. 1. 22. 2003. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000180837500006&KeyUID=WOS:000180837500006 . 10.1080/10915810390181490 . International Journal of Toxicology

Dexamethasone prevents GM-CSF induced NF-kB activation, iNOS expression and NO production in a skin dendritic cell line

Vital, A. L.; Gonçalo, Margarida; Cruz, Maria Teresa; Duarte, Carlos B.; Figueiredo, Américo; Carvalho A. P.; Lopes, Maria Celeste, 2003. Mediators Inflammation . 71 - 78. 12. 2003. published Mediators Inflammation

The Sensitizer 2,4-Dinitrofluorobenzene Activates Caspase-3 and Induces Cell Death in a Skin Dendritic Cell Line

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Figueiredo, Américo; Carvalho, Arsélio P.; Lopes, Maria Celeste, 2003. 2003. http://hdl.handle.net/10316/11811 .

Differential activation of nuclear factor kappa B subunits in a skin dendritic cell line in response to the strong sensitizer 2,4-dinitrofluorobenzene.

Cruz MT; Duarte CB; Gonçalo M; Figueiredo A; Carvalho AP; Lopes MC; Cruz, M. T.; et al, 2002. Archives of Dermatological Research. 419 - 425. 9. 294. 2002. http://europepmc.org/abstract/med/12522580 . 10.1007/s00403-002-0342-y . Archives of Dermatological Research

Granulocyte-macrophage colony-stimulating factor activates the transcription of nuclear factor kappa B and induces the expression of nitric oxide synthase in a skin dendritic cell line

Cruz, M.T.; Duarte, C.B.; Gonçalo, M.; Figueiredo, A.; Carvalho, A.P.; Lopes, M.C., 2001. Immunology and Cell Biology. 590 - 596. 6. 79. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035176476&partnerID=MN8TOARS . 10.1046/j.1440-1711.2001.01041.x . Immunology and Cell Biology

LPS induction of IkB-¿ degradation and iNOS expression in a skin dendritic cell line is prevented by the Janus Kinase 2 inhibitor, tyrphostin B42

Cruz, Maria Teresa; Duarte, Carlos B.; Gonçalo, Margarida; Carvalho A. P.; Lopes, Maria Celeste; Cruz, M.T.; Duarte, C.B.; et al, 2001. Nitric Oxide: Biology and Chemistry . 53 - 61. 5. 5. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035708551&partnerID=MN8TOARS . 10.1006/niox.2000.0320 . published Nitric Oxide: Biology and Chemistry

Involvement of JAK2 and MAPK on type II nitric oxide synthase expression in skin-derived dendritic cells

Cruz, M.T.; Duarte, C.B.; Gonçalo, M.; Carvalho, A.P.; Lopes, M.G.; Cruz, M. T.; Duarte, C. B.; et al, 1999. American Journal of Physiology - Cell Physiology. C1050 - C1057. 6 46-6. 277. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033373205&partnerID=MN8TOARS . 10.1152/AJPCELL.1999.277.6.C1050 . American Journal of Physiology - Cell Physiology

Photosensitization of lymphoblastoid cells with phthalocyanines at different saturating incubation times

Gomes, E. R.; Cruz, T.; Lopes, C. F.; Carvalho, A. P.; Duarte, C. B.; Gomes, E.R.; Lopes, C.F.; Carvalho, A.P.; Duarte, C.B., 1999. Cell Biology and Toxicology. 249 - 260. 4. 15. 1999. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000084642800005&KeyUID=WOS:000084642800005 . 10.1023/a:1007615813184 . Cell Biology and Toxicology

Calcium-dependent nitric oxide synthase activity in rat thymocytes

Cruz, M.T.; Carmo, A.; Carvalho, A.P.; Lopes, M.C., 1998. Biochemical and Biophysical Research Communications. 98 - 103. 1. 248. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032499870&partnerID=MN8TOARS . 10.1006/bbrc.1998.8865 . Biochemical and Biophysical Research Communications

Inhibition of ROS production prevents IL-1ß-induced iNOS expression in articular chondrocytes

Mendes, AF; Wong, H; Caramona, MM; Carvalho, AP; Lopes, MC; Cruz, TF, 1998. Naunyn-Schmiedeberg's Archives of Pharmacology. 1998. https://publons.com/wos-op/publon/10621892/ . Naunyn-Schmiedeberg's Archives of Pharmacology

Interaction between polyalkylcyanoacrylate nanoparticles and peritoneal macrophages: MTT metabolism, NBT reduction, and NO production

Cruz, T.; Gaspar, R.; Donato, A.; Lopes, C., 1997. Pharmaceutical Research. 73 - 79. 1. 14. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031042535&partnerID=MN8TOARS . 10.1023/A:1012059501947 . Pharmaceutical Research

Past R&D Projects

Awards

1993

Prize awarded by the Order of Pharmacists to the student with the highest classification in the Degree of Branch A - Officinal and Hospital Pharmacy

2008

Prix de Recherche Sientific Lierac

2010

Award “Arrisca Coimbra 2010”

2011

Cotec Award (2nd place)

2018

Prize for the best work presented in the field of Basic Research, by the European Contact Dermatitis Society

2020

Colgate-Palmolive Grants for Alternative Research (team member)

Development of a Defined Approach for Respiratory Sensitization Hazard Assessment

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