MitoLab: Mitochondrial Signaling and Metabolic Dysfunction

Loss of epigenetic information as a cause of mammalian aging

Yang, Jae-Hyun; Hayano, Motoshi; Griffin, Patrick T.; Amorim, João A.; Bonkowski, Michael S.; Apostolides, John K.; Salfati, Elias L.; et al, 2023. Cell. 305 - 326.e27. 2. 186. 2023. http://dx.doi.org/10.1016/j.cell.2022.12.027 . 10.1016/j.cell.2022.12.027 . Cell

Liver Graft Hypothermic Static and Oxygenated Perfusion (HOPE) Strategies: A Mitochondrial Crossroads

Raquel G. Bardallo; Rui T. Da Silva; Teresa Carbonell; Carlos Palmeira; Emma Folch-Puy; Joan Roselló-Catafau; René Adam; Arnau Panisello-Rosello, 2022. International Journal of Molecular Sciences. 5742 - 5742. 10. 23. 2022. https://doi.org/10.3390/ijms23105742 . 10.3390/ijms23105742 . International Journal of Molecular Sciences

Mitochondrial and metabolic dysfunction in ageing and age-related diseases

Amorim, João A.; Coppotelli, Giuseppe; Rolo, Anabela P.; Palmeira, Carlos M.; Ross, Jaime M.; Sinclair, David A., 2022. Nature Reviews Endocrinology. 2022. http://dx.doi.org/10.1038/s41574-021-00626-7 . 10.1038/s41574-021-00626-7 . Nature Reviews Endocrinology

Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria

João S. Teodoro; Rui T. Da Silva; Ivo F. Machado; Arnau Panisello-Roselló; Joan Roselló-Catafau; Anabela P. Rolo; Carlos M. Palmeira, 2022. Cells. 688 - 688. 4. 11. 2022. https://doi.org/10.3390/cells11040688 . 10.3390/cells11040688 . Cells

PEG35 as a Preconditioning Agent against Hypoxia/Reoxygenation Injury

Rui Teixeira da Silva; Ivo F. Machado; João S. Teodoro; Arnau Panisello-Roselló; Joan Roselló-Catafau; Anabela P. Rolo; Carlos M. Palmeira, 2022. International Journal of Molecular Sciences. 1156 - 1156. 3. 23. 2022. https://doi.org/10.3390/ijms23031156 . 10.3390/ijms23031156 . International Journal of Molecular Sciences

IGL-2 as a Unique Solution for Cold Static Preservation and Machine Perfusion in Liver and Mitochondrial Protection

Rui Teixeira Da Silva; Raquel G. Bardallo; Emma Folch-Puy; Teresa Carbonell; Carlos M. Palmeira; Constantino Fondevila; René Adam; Joan Roselló-Catafau; Arnau Panisello-Roselló, 2022. Transplantation Proceedings. 73 - 76. 1. 54. 2022. https://doi.org/10.1016/j.transproceed.2021.10.008 . 10.1016/j.transproceed.2021.10.008 . Transplantation Proceedings

Chenodeoxycholic Acid Has Non-Thermogenic, Mitodynamic Anti-Obesity Effects in an In Vitro CRISPR/Cas9 Model of Bile Acid Receptor TGR5 Knockdown

Teodoro, João S.; Machado, Ivo F.; Castela, Ana C.; Amorim, João A.; Jarak, Ivana; Carvalho, Rui A.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. International Journal of Molecular Sciences. 21. 22. 2021. http://dx.doi.org/10.3390/ijms222111738 . 10.3390/ijms222111738 . International Journal of Molecular Sciences

Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics

Sara Nunes; Sofia D. Viana; Inês Preguiça; André Alves; R. Fernandes; Teodoro, J.S.; Patrícia Matos; et al, 2021. Nutrients. 2021. https://www.mdpi.com/2072-6643/13/12/4192 . 10.3390/nu13124192 . Nutrients

miR-378a-3p Participates in Metformin’s Mechanism of Action on C2C12 Cells under Hyperglycemia

Machado, Ivo F.; Teodoro, João S.; Castela, Ana C.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. International Journal of Molecular Sciences. 2. 22. 2021. http://dx.doi.org/10.3390/ijms22020541 . 10.3390/ijms22020541 . International Journal of Molecular Sciences

The potential role of sestrin 2 in liver regeneration

Oliveira, Raúl P.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. Free Radical Biology and Medicine. 255 - 267. 163. 2021. http://dx.doi.org/10.1016/j.freeradbiomed.2020.12.027 . 10.1016/j.freeradbiomed.2020.12.027 . Free Radical Biology and Medicine

Sestrin2 and mitochondrial quality control: Potential impact in myogenic differentiation

Piochi, Luiz F.; Machado, Ivo F.; Palmeira, Carlos M.; Rolo, Anabela P., 2021. Ageing Research Reviews. 67. 2021. http://dx.doi.org/10.1016/j.arr.2021.101309 . 10.1016/j.arr.2021.101309 . Ageing Research Reviews

The yin and yang faces of the mitochondrial deacetylase sirtuin 3 in age-related disorders

Gomes, P.; Viana, S.D.; Nunes, S.; Rolo, A.P.; Palmeira, C.M.; Reis, F., 2020. Ageing Research Reviews. 57. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076952156&partnerID=MN8TOARS . 10.1016/j.arr.2019.100983 . Ageing Research Reviews

Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H<inf>2</inf>O<inf>2</inf>-Dependent Mechanism

Almeida, N.; Carrara, G.; Palmeira, C.M.; Fernandes, A.S.; Parsons, M.; Smith, G.L.; Saraiva, N., 2020. Redox Biology. 28. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074222003&partnerID=MN8TOARS . 10.1016/j.redox.2019.101361 . Redox Biology

Altered mitochondrial metabolism in the insulin-resistant heart

Makrecka-Kuka, M.; Liepinsh, E.; Murray, A.J.; Lemieux, H.; Dambrova, M.; Tepp, K.; Puurand, M.; et al, 2020. Acta Physiologica. 3. 228. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077842678&partnerID=MN8TOARS . 10.1111/apha.13430 . Acta Physiologica

Blueberry Consumption Challenges Hepatic Mitochondrial Bioenergetics and Elicits Transcriptomics Reprogramming in Healthy Wistar Rats

Nunes, Sara; Viana, Sofia D.; Preguiça, Inês; Alves, André; Fernandes, Rosa; Teodoro, João S.; Figueirinha, Artur; et al, 2020. Pharmaceutics. 11. 12. 2020. http://dx.doi.org/10.3390/pharmaceutics12111094 . 10.3390/pharmaceutics12111094 . Pharmaceutics

Exploration of the cellular effects of the high-dose, long-term exposure to coffee roasting product furan and its by-product cis-2-butene-1,4-dial on human and rat hepatocytes

João S. Teodoro; Rui Silva; António Aguiar; Abílio J. F. N. Sobral; Anabela P. Rolo; Carlos M. Palmeira, 2020. Toxicology Mechanisms and Methods. 536 - 545. 7. 30. 2020. https://doi.org/10.1080/15376516.2020.1780361 . 10.1080/15376516.2020.1780361 . Toxicology Mechanisms and Methods

The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function

Teodoro, João S.; Amorim, João A.; Machado, Ivo F.; Castela, Ana C.; Steegborn, Clemens; Sinclair, David A.; Rolo, Anabela P.; Palmeira, Carlos M., 2020. International Journal of Molecular Sciences. 14. 21. 2020. http://dx.doi.org/10.3390/ijms21144896 . 10.3390/ijms21144896 . International Journal of Molecular Sciences

Correspondence

Alexandrino, H.; Palmeira, C., 2019. British Journal of Surgery. 152 - 152. 1. 106. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058912518&partnerID=MN8TOARS . 10.1002/bjs.11055 . British Journal of Surgery

miR-378a: a new emerging microRNA in metabolism

Machado, I.F.; Teodoro, J.S.; Palmeira, C.M.; Rolo, A.P., 2019. Cellular and Molecular Life Sciences. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075434955&partnerID=MN8TOARS . 10.1007/s00018-019-03375-z . Cellular and Molecular Life Sciences

Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins, Rui Miguel; Teodoro, João Soeiro; Furtado, Emanuel; Rolo, Anabela Pinto; Palmeira, Carlos Marques; Tralhão, José Guilherme; Martins, R.M.; et al, 2019. Clinical and Molecular Hepatology. 190 - 198. 2. 25. 2019. http://dx.doi.org/10.3350/cmh.2018.0087 . 10.3350/cmh.2018.0087 . Clinical and Molecular Hepatology

Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes

Teodoro, J.S.; Nunes, S.; Rolo, A.P.; Reis, F.; Palmeira, C.M., 2019. Frontiers in Physiology. JAN. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065463466&partnerID=MN8TOARS . 10.3389/fphys.2018.01857 . Frontiers in Physiology

Mild hypothermia during the reperfusion phase protects mitochondrial bioenergetics against ischemia-reperfusion injury in an animal model of ex-vivo liver transplantation—An experimental study

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Rolo, A.P.; Palmeira, C.M., 2019. International Journal of Medical Sciences. 1304 - 1312. 9. 16. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072941379&partnerID=MN8TOARS . 10.7150/ijms.34617 . International Journal of Medical Sciences

Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A<inf>2A</inf> receptor over-activation in a rat model of Parkinson's disease

Carmo, M.; Gonçalves, F.Q.; Canas, P.M.; Oses, J.-P.; Fernandes, F.D.; Duarte, F.V.; Palmeira, C.M.; et al, 2019. British Journal of Pharmacology. 3666 - 3680. 18. 176. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070072977&partnerID=MN8TOARS . 10.1111/bph.14771 . British Journal of Pharmacology

Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins

Palmeira, C.M.; Teodoro, J.S.; Amorim, J.A.; Steegborn, C.; Sinclair, D.A.; Rolo, A.P., 2019. Free Radical Biology and Medicine. 483 - 491. 141. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85069629808&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2019.07.017 . Free Radical Biology and Medicine

Research update for articles published in EJCI in 2016

Adlbrecht, C.; Blanco-Verea, A.; Bouzas-Mosquera, M.C.; Brion, M.; Burtscher, M.; Carbone, F.; Chang, T.-T.; et al, 2018. European Journal of Clinical Investigation. 10. 48. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85053529293&partnerID=MN8TOARS . 10.1111/eci.13016 . European Journal of Clinical Investigation

Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update

Panisello-Roselló, A.; Lopez, A.; Folch-Puy, E.; Carbonell, T.; Rolo, A.; Palmeira, C.; Adam, R.; Net, M.; Roselló-Catafau, J., 2018. World Journal of Gastroenterology. 2984 - 2994. 27. 24. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050972436&partnerID=MN8TOARS . 10.3748/wjg.v24.i27.2984 . World Journal of Gastroenterology

Mitochondrial damage and apoptosis: Key features in BDE-153-induced hepatotoxicity

Pereira, L.C.; Cabral Miranda, L.F.; Franco-Bernardes, M.F.; Tasso, M.J.; Duarte, F.V.; Inácio Varela, A.T.; Rolo, A.P.; Marques Palmeira, C.M.; Dorta, D.J., 2018. Chemico-Biological Interactions. 192 - 201. 291. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049064624&partnerID=MN8TOARS . 10.1016/j.cbi.2018.06.021 . Chemico-Biological Interactions

Recent insights into mitochondrial targeting strategies in liver transplantation

Martins, R.M.; Teodoro, J.S.; Furtado, E.; Rolo, A.P.; Palmeira, C.M.; Tralhão, J.G., 2018. International Journal of Medical Sciences. 248 - 256. 3. 15. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045188539&partnerID=MN8TOARS . 10.7150/ijms.22891 . International Journal of Medical Sciences

Cytoprotective mechanisms in fatty liver preservation against cold ischemia injury: A comparison between IGL-1 and HTK

Panisello-Roselló, A.; Verde, E.; Lopez, A.; Flores, M.; Folch-Puy, E.; Rolo, A.; Palmeira, C.; et al, 2018. International Journal of Molecular Sciences. 2. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041019515&partnerID=MN8TOARS . 10.3390/ijms19020348 . International Journal of Molecular Sciences

Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al, 2018. Redox Biology. 694 - 696. 14. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032289195&partnerID=MN8TOARS . 10.1016/j.redox.2017.10.001 . Redox Biology

Addition of berberine to preservation solution in an animal model of ex vivo liver transplant preserves mitochondrial function and bioenergetics from the damage induced by ischemia/reperfusion

Martins, R.M.; Rolo, A.P.; Teodoro, J.S.; Furtado, E.; Oliveira, R.C.; Tralhão, J.G.; Palmeira, C.M., 2018. International Journal of Molecular Sciences. 1. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040938454&partnerID=MN8TOARS . 10.3390/ijms19010284 . International Journal of Molecular Sciences

Indirubin and NAD⁺ prevent mitochondrial ischaemia/reperfusion damage in fatty livers

Teodoro, J.S.; Varela, A.T.; Duarte, F.V.; Gomes, A.P.; Palmeira, C.M.; Rolo, A.P., 2018. European Journal of Clinical Investigation. 6. 48. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85045238716&partnerID=MN8TOARS . 10.1111/eci.12932 . European Journal of Clinical Investigation

Aldehyde dehydrogenase 2 (ALDH2) in rat fatty liver cold ischemia injury

Panisello-Roselló, A.; Alva, N.; Flores, M.; Lopez, A.; Benítez, C.C.; Folch-Puy, E.; Rolo, A.; et al, 2018. International Journal of Molecular Sciences. 9. 19. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85052507134&partnerID=MN8TOARS . 10.3390/ijms19092479 . International Journal of Molecular Sciences

GSK3ß and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.

Zaouali MA; Panisello A; Lopez A; Castro C; Folch E; Carbonell T; Rolo A; et al, 2017. 2017. http://europepmc.org/abstract/med/28282906 . 10.3390/ijms18030591 .

Adenosine receptors: regulatory players in the preservation of mitochondrial function induced by ischemic preconditioning of rat liver

Duarte, F.V.; Amorim, J.A.; Varela, A.T.; Teodoro, J.S.; Gomes, A.P.; Cunha, R.A.; Palmeira, C.M.; et al, 2017. Purinergic Signalling. 179 - 190. 2. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995486129&partnerID=MN8TOARS . 10.1007/s11302-016-9548-x . Purinergic Signalling

An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity.

Pereira LC; Duarte FV; Varela AT; Rolo AP; Palmeira CM; Dorta DJ, 2017. 2017. http://europepmc.org/abstract/med/27234317 . 10.1016/j.tox.2016.05.022 .

Exposure to BDE-153 induces autophagy in HepG2 cells.

Pereira LC; Duarte FV; Varela ATIF; Rolo AP; Palmeira CMM; Dorta DJ, 2017. 2017. http://europepmc.org/abstract/med/28396260 . 10.1016/j.tiv.2017.04.005 .

Lack of additive effects of resveratrol and energy restriction in the treatment of hepatic steatosis in rats

Milton-Laskibar, I.; Aguirre, L.; Fernández-Quintela, A.; Rolo, A.P.; Teodoro, J.S.; Palmeira, C.M.; Portillo, M.P., 2017. Nutrients. 7. 9. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023760594&partnerID=MN8TOARS . 10.3390/nu9070737 . Nutrients

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al, 2017. Redox Biology. 94 - 162. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020032301&partnerID=MN8TOARS . 10.1016/j.redox.2017.05.007 . Redox Biology

Bioenergetic adaptations of the human liver in the ALPPS procedure – how liver regeneration correlates with mitochondrial energy status

Alexandrino, H.; Rolo, A.; Teodoro, J.S.; Donato, H.; Martins, R.; Serôdio, M.; Martins, M.; et al, 2017. HPB. 1091 - 1103. 12. 19. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029605721&partnerID=MN8TOARS . 10.1016/j.hpb.2017.08.005 . HPB

Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-ß Peptides Modeling Alzheimer's Disease

Amorim, J.A.; Canas, P.M.; Tomé, A.R.; Rolo, A.P.; Agostinho, P.; Palmeira, C.M.; Cunha, R.A., 2017. Journal of Alzheimer's Disease. 525 - 536. 2. 60. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029613373&partnerID=MN8TOARS . 10.3233/JAD-170356 . Journal of Alzheimer's Disease

Unacylated ghrelin prevents mitochondrial dysfunction in a model of ischemia/reperfusion liver injury

Rossetti, A.; Togliatto, G.; Rolo, A.P.; Teodoro, J.S.; Granata, R.; Ghigo, E.; Columbano, A.; Palmeira, C.M.; Brizzi, M.F., 2017. Cell Death Discovery. 1. 3. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85051289736&partnerID=MN8TOARS . 10.1038/cddiscovery.2017.77 . Cell Death Discovery

Exposure to decabromodiphenyl ether (BDE-209) produces mitochondrial dysfunction in rat liver and cell death

Pereira, L.C.; Souza, A.O.; Tasso, M.J.; Oliveira, A.M.C.; Duarte, F.V.; Palmeira, C.M.; Dorta, D.J., 2017. Journal of Toxicology and Environmental Health - Part A: Current Issues. 1129 - 1144. 19-21. 80. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85033371791&partnerID=MN8TOARS . 10.1080/15287394.2017.1357370 . Journal of Toxicology and Environmental Health - Part A: Current Issues

Evaluation of Polybrominated Diphenyl Ether Toxicity on HepG2 Cells - Hexabrominated Congener (BDE-154) Is Less Toxic than Tetrabrominated Congener (BDE-47).

Souza AO; Tasso MJ; Oliveira AM; Pereira LC; Duarte FV; Oliveira DP; Palmeira CM; Dorta DJ, 2016. 2016. http://europepmc.org/abstract/med/27060917 . 10.1111/bcpt.12598 .

Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague-Dawley rats.

Teodoro JS; Silva R; Varela AT; Duarte FV; Rolo AP; Hussain S; Palmeira CM, 2016. 2016. http://europepmc.org/abstract/med/27171910 . 10.2217/nnm-2016-0049 .

Mitochondrial bioenergetics and posthepatectomy liver dysfunction.

Alexandrino H; Varela AT; Teodoro JS; Martins MA; Rolo AP; Tralhão JG; Palmeira CM; Castro E Sousa F, 2016. 2016. http://europepmc.org/abstract/med/27138992 . 10.1111/eci.12639 .

Hepatic and skeletal muscle mitochondrial toxicity of chitosan oligosaccharides of normal and diabetic rats.

Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM, 2016. 2016. http://europepmc.org/abstract/med/27790925 . 10.1080/15376516.2016.1222643 .

The bile acid chenodeoxycholic acid directly modulates metabolic pathways in white adipose tissue in vitro: insight into how bile acids decrease obesity.

Teodoro JS; Rolo AP; Jarak I; Palmeira CM; Carvalho RA, 2016. 2016. http://europepmc.org/abstract/med/27488269 . 10.1002/nbm.3583 .

Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?

Görlach A; Dimova EY; Petry A; Martínez-Ruiz A; Hernansanz-Agustín P; Rolo AP; Palmeira CM; Kietzmann T, 2015. 2015. http://europepmc.org/abstract/med/26339717 . 10.1016/j.redox.2015.08.016 .

Impairment of mitochondrial energy metabolism of two marine fish by in vitro mercuric chloride exposure.

Mieiro CL; Pardal M; Duarte A; Pereira E; Palmeira CM, 2015. 2015. http://europepmc.org/abstract/med/26026249 . 10.1016/j.marpolbul.2015.05.054 .

Regulation of Mitochondrial Function and its Impact in Metabolic Stress.

Duarte FV; Amorim JA; Palmeira CM; Rolo AP, 2015. 2015. http://europepmc.org/abstract/med/25973983 . 10.2174/0929867322666150514095910 .

Editorial: Metabolic Diseases: Drugs and Mitochondrial Targets.

Palmeira CM; Rolo AP; Palmeira, C.M.; Rolo, A.P., 2015. Current Medicinal Chemistry. 20. 22. 2015. http://europepmc.org/abstract/med/26549543 . 10.2174/092986732220150722123617 . Current Medicinal Chemistry

Biochemical and physiological responses of Carcinus maenas to temperature and the fungicide azoxystrobin.

Rodrigues ET; Moreno A; Mendes T; Palmeira C; Pardal MÂ, 2015. 2015. http://europepmc.org/abstract/med/25835271 . 10.1016/j.chemosphere.2015.03.011 .

PPARa Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury.

Pantazi E; Folch-Puy E; Bejaoui M; Panisello A; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J, 2015. 2015. http://europepmc.org/abstract/med/26539534 . 10.1155/2015/894679 .

Losartan activates sirtuin 1 in rat reduced-size orthotopic liver transplantation.

Pantazi E; Bejaoui M; Zaouali MA; Folch-Puy E; Pinto Rolo A; Panisello A; Palmeira CM; Roselló-Catafau J, 2015. 2015. http://europepmc.org/abstract/med/26185373 . 10.3748/wjg.v21.i26.8021 .

Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach.

Pantazi E; Zaouali MA; Bejaoui M; Folch-Puy E; Ben Abdennebi H; Varela AT; Rolo AP; Palmeira CM; Roselló-Catafau J, 2015. 2015. http://europepmc.org/abstract/med/25684941 . 10.3748/wjg.v21.i6.1765 .

Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice.

Teodoro JS; Zouhar P; Flachs P; Bardova K; Janovska P; Gomes AP; Duarte FV; et al, 2014. 2014. http://europepmc.org/abstract/med/24310401 . 10.1038/ijo.2013.230 .

The Role of microRNAs in Mitochondria: Small Players Acting Wide.

Duarte FV; Palmeira CM; Rolo AP, 2014. 2014. http://europepmc.org/abstract/med/25264560 . 10.3390/genes5040865 .

High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.

Teodoro JS; Varela AT; Rolo AP; Palmeira CM, 2014. 2014. http://europepmc.org/abstract/med/24842072 . 10.1007/s12263-014-0406-6 .

The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.

Carmo MR; Menezes AP; Nunes AC; Pliássova A; Rolo AP; Palmeira CM; Cunha RA; Canas PM; Andrade GM, 2014. 2014. http://europepmc.org/abstract/med/24508709 . 10.1016/j.neuropharm.2014.01.045 .

Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.

Teodoro JS; Gomes AP; Varela AT; Duarte FV; Rolo AP; Palmeira CM, 2013. 2013. http://europepmc.org/abstract/med/23292031 . 10.1007/s11010-012-1555-9 .

The NAD ratio redox paradox: why does too much reductive power cause oxidative stress?

Teodoro JS; Rolo AP; Palmeira CM, 2013. 2013. http://europepmc.org/abstract/med/23256455 . 10.3109/15376516.2012.759305 .

Dibenzofuran-induced mitochondrial dysfunction: Interaction with ANT carrier

Duarte, F.V.; Gomes, A.P.; Teodoro, J.S.; Varela, A.T.; Moreno, A.J.M.; Rolo, A.P.; Palmeira, C.M., 2013. Toxicology in Vitro. 2160 - 2168. 8. 27. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885795993&partnerID=MN8TOARS . 10.1016/j.tiv.2013.08.009 . Toxicology in Vitro

Cumulative Mitoxantrone-induced Haematological and Hepatic Adverse Effects in a Sub-Chronic In Vivo Study.

Rossato LG; Costa VM; Dallegrave E; Arbo M; Dinis-Oliveira RJ; Santos-Silva A; Duarte JA; et al, 2013. 2013. http://europepmc.org/abstract/med/24119282 . 10.1111/bcpt.12143 .

The metabolic profile of mitoxantrone and its relation with mitoxantrone-induced cardiotoxicity.

Rossato LG; Costa VM; de Pinho PG; Arbo MD; de Freitas V; Vilain L; de Lourdes Bastos M; Palmeira C; Remião F, 2013. 2013. http://europepmc.org/abstract/med/23545721 . 10.1007/s00204-013-1040-6 .

Mitochondrial Cumulative Damage Induced by Mitoxantrone: Late Onset Cardiac Energetic Impairment.

Rossato LG; Costa VM; Dallegrave E; Arbo M; Silva R; Ferreira R; Amado F; et al, 2013. 2013. http://europepmc.org/abstract/med/24096626 . 10.1007/s12012-013-9230-2 .

Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging.

Gomes AP; Price NL; Ling AJ; Moslehi JJ; Montgomery MK; Rajman L; White JP; et al, 2013. 2013. http://europepmc.org/abstract/med/24360282 . 10.1016/j.cell.2013.11.037 .

Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation

Teodoro, J.S.; Duarte, F.V.; Gomes, A.P.; Varela, A.T.; Peixoto, F.M.; Rolo, A.P.; Palmeira, C.M., 2013. Mitochondrion. 637 - 646. 6. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884937949&partnerID=MN8TOARS . 10.1016/j.mito.2013.09.002 . Mitochondrion

Therapeutic concentrations of mitoxantrone elicit energetic imbalance in H9c2 cells as an earlier event

Rossato, L.G.; Costa, V.M.; Vilas-Boas, V.; De Lourdes Bastos, M.; Rolo, A.; Palmeira, C.; Remião, F., 2013. Cardiovascular Toxicology. 413 - 425. 4. 13. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890559945&partnerID=MN8TOARS . 10.1007/s12012-013-9224-0 . Cardiovascular Toxicology

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis.

Gomes AP; Duarte FV; Nunes P; Hubbard BP; Teodoro JS; Varela AT; Jones JG; et al, 2012. 2012. http://europepmc.org/abstract/med/22027215 . 10.1016/j.bbadis.2011.10.008 .

Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis.

Rolo AP; Teodoro JS; Palmeira CM, 2012. 2012. http://europepmc.org/abstract/med/22064361 . 10.1016/j.freeradbiomed.2011.10.003 .

Preface

Palmeira, C.M.; Moreno, A.J., 2012. Methods in Molecular Biology. 810. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-82355193804&partnerID=MN8TOARS . Methods in Molecular Biology

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.

Price NL; Gomes AP; Ling AJ; Duarte FV; Martin-Montalvo A; North BJ; Agarwal B; et al, 2012. 2012. http://europepmc.org/abstract/med/22560220 . 10.1016/j.cmet.2012.04.003 .

Nerolidol effects on mitochondrial and cellular energetics.

Ferreira FM; Palmeira CM; Oliveira MM; Santos D; Simões AM; Rocha SM; Coimbra MA; Peixoto F, 2012. 2012. http://europepmc.org/abstract/med/22138475 . 10.1016/j.tiv.2011.11.009 .

Antioxidant capacity and toxicological evaluation of Pterospartum tridentatum flower extracts

Ferreira, F.M.; Dinis, L.T.; Azedo, P.; Galhano, C.I.C.; Simões, A.; Cardoso, S.M.; Domingues, M.R.M.; et al, 2012. CYTA - Journal of Food. 92 - 102. 2. 10. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860268444&partnerID=MN8TOARS . 10.1080/19476337.2011.590233 . CYTA - Journal of Food

Exposure to dibenzofuran triggers autophagy in lung cells.

Duarte FV; Teodoro JS; Rolo AP; Palmeira CM, 2012. 2012. http://europepmc.org/abstract/med/22173198 . 10.1016/j.toxlet.2011.11.029 .

Hepatic FXR: key regulator of whole-body energy metabolism.

Teodoro JS; Rolo AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21862343 . 10.1016/j.tem.2011.07.002 .

Exposure to dibenzofuran affects lung mitochondrial function in vitro.

Duarte FV; Simões AM; Teodoro JS; Rolo AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21554085 . 10.3109/15376516.2011.576714 .

Fatty liver and ischemia/reperfusion: are there drugs able to mitigate injury?

Varela AT; Rolo AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/22050747 . 10.2174/092986711797535164 .

Regulation of mitochondrial biogenesis in metabolic syndrome.

Rolo AP; Gomes AP; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21269264 . 10.2174/138945011795529056 .

Assessment of the toxicity of silver nanoparticles in vitro: a mitochondrial perspective.

Teodoro JS; Simões AM; Duarte FV; Rolo AP; Murdoch RC; Hussain SM; Palmeira CM, 2011. 2011. http://europepmc.org/abstract/med/21232593 . 10.1016/j.tiv.2011.01.004 .

Differential sex, morphotype and tissue accumulation of mercury in the crab Carcinus maenas

Costa, S.; Viegas, I.; Pereira, E.; Duarte, A.C.; Palmeira, C.M.; Pardal, M.A., 2011. Water, Air, and Soil Pollution. 65 - 75. 1-4. 222. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-80755188894&partnerID=MN8TOARS . 10.1007/s11270-011-0809-6 . Water, Air, and Soil Pollution

Ursodeoxycholic acid treatment of hepatic steatosis: a (13)C NMR metabolic study.

Nunes PM; Jones JG; Rolo AP; Palmeira CM; Carvalho RA, 2011. 2011. http://europepmc.org/abstract/med/21538633 . 10.1002/nbm.1672 .

Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy.

Carvalho RA; Sousa RP; Cadete VJ; Lopaschuk GD; Palmeira CM; Bjork JA; Wallace KB, 2010. 2010. http://europepmc.org/abstract/med/20132857 . 10.1016/j.tox.2010.01.019 .

Indirubin-3'-oxime prevents hepatic I/R damage by inhibiting GSK-3beta and mitochondrial permeability transition.

Varela AT; Simões AM; Teodoro JS; Duarte FV; Gomes AP; Palmeira CM; Rolo AP, 2010. 2010. http://europepmc.org/abstract/med/20433952 . 10.1016/j.mito.2010.04.006 .

Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

Hafner, A.V.; Dai, J.; Gomes, A.P.; Xiao, C.-Y.; Palmeira, K.C.M.; Rosenzweig, A.; Sinclair, D.A.; et al, 2010. Aging. 914 - 923. 12. 2. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952266729&partnerID=MN8TOARS . Aging

Exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and tetraethyl lead affects lung mitochondria bioenergetics.

Simões AM; Duarte FV; Teodoro JS; Rolo AP; Palmeira CM, 2010. 2010. http://europepmc.org/abstract/med/20158383 . 10.3109/15376510903527916 .

Prevention of I/R injury in fatty livers by ischemic preconditioning is associated with increased mitochondrial tolerance: the key role of ATPsynthase and mitochondrial permeability transition.

Rolo AP; Teodoro JS; Peralta C; Rosello-Catafau J; Palmeira CM, 2009. 2009. http://europepmc.org/abstract/med/19619169 . 10.1111/j.1432-2277.2009.00916.x .

Biosensor plates detect mitochondrial physiological regulators and mutations in vivo.

Rolo AP; Palmeira CM; Cortopassi GA, 2009. 2009. http://europepmc.org/abstract/med/18950600 . 10.1016/j.ab.2008.10.002 .

Differential alterations in mitochondrial function induced by a choline-deficient diet: understanding fatty liver disease progression.

Teodoro JS; Rolo AP; Duarte FV; Simões AM; Palmeira CM, 2008. 2008. http://europepmc.org/abstract/med/18765303 . 10.1016/j.mito.2008.07.008 .

Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction.

Varela AT; Gomes AP; Simões AM; Teodoro JS; Duarte FV; Rolo AP; Palmeira CM, 2008. 2008. http://europepmc.org/abstract/med/18786556 . 10.1016/j.taap.2008.08.005 .

Estimating gluconeogenesis by NMR isotopomer distribution analysis of [13C]bicarbonate and [1-13C]lactate.

Alves TC; Nunes PM; Palmeira CM; Jones JG; Carvalho RA, 2008. 2008. http://europepmc.org/abstract/med/17683055 . 10.1002/nbm.1195 .

Evaluation of olive oil mill wastewater toxicity on the mitochondrial bioenergetics after treatment with Candida oleophila

Peixoto, F.; Martins, F.; Amaral, C.; Gomes-Laranjo, J.; Almeida, J.; Palmeira, C.M., 2008. Ecotoxicology and Environmental Safety. 266 - 275. 2. 70. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-42049108014&partnerID=MN8TOARS . 10.1016/j.ecoenv.2007.11.003 . Ecotoxicology and Environmental Safety

Mitochondria a key role in microcystin-LR kidney intoxication.

La-Salete R; Oliveira MM; Palmeira CA; Almeida J; Peixoto FP, 2008. 2008. http://europepmc.org/abstract/med/17461434 . 10.1002/jat.1251 .

Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis.

Palmeira CM; Rolo AP; Berthiaume J; Bjork JA; Wallace KB, 2007. 2007. http://europepmc.org/abstract/med/17761203 . 10.1016/j.taap.2007.07.015 .

Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.

Rolo AP; Palmeira CM, 2006. 2006. http://europepmc.org/abstract/med/16490224 . 10.1016/j.taap.2006.01.003 .

Mitochondrial Bioenergetics, Diabetes, and Aging: Top-Down Analysis Using the Diabetic Goto-Kakizaki (GK) Rat as a Model.

Ferreira FM; Moreno AJ; Seiça R; Santos MS; Palmeira CM, 2006. 2006. http://europepmc.org/abstract/med/20021031 . 10.1080/15376520600616925 .

Decreased ANT content in Zucker fatty rats: relevance for altered hepatic mitochondrial bioenergetics in steatosis.

Teodoro J; Rolo AP; Oliveira PJ; Palmeira CM, 2006. 2006. http://europepmc.org/abstract/med/16554051 . 10.1016/j.febslet.2006.02.078 .

Bile acids are toxic for isolated cardiac mitochondria: A possible cause for hepatic-derived cardiomyopathies?

Ferreira, M.; Coxito, P.M.; Sardão, V.A.; Palmeira, C.M.; Oliveira, P.J.; Ferreira M; Coxito PM; et al, 2005. Cardiovascular Toxicology. 63 - 73. 1. 5. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18544374442&partnerID=MN8TOARS . 10.1385/CT:5:1:063 . Cardiovascular Toxicology

Mitochondrial function is not affected by renal morphological changes in diabetic goto-kakizaki rat.

Seiça R; Santos DL; Palmeira CM; Moreno AJ; Sena C; Cunha MF; Santos MS, 2005. 2005. http://europepmc.org/abstract/med/20021090 . 10.1080/15376520590968806 .

Mitochondrially-mediated toxicity of bile acids.

Palmeira CM; Rolo AP, 2004. 2004. http://europepmc.org/abstract/med/15363577 . 10.1016/j.tox.2004.06.001 .

Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.

Rolo AP; Palmeira CM; Holy JM; Wallace KB, 2004. 2004. http://europepmc.org/abstract/med/14976352 . 10.1093/toxsci/kfh078 .

Carvedilol inhibits the mitochondrial permeability transition by an antioxidant mechanism.

Oliveira PJ; Esteves T; Rolo AP; Palmeira CM; Moreno AJ, 2004. 2004. http://europepmc.org/abstract/med/15034201 . 10.1385/CT:4:1:11 .

Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function.

Oliveira PJ; Rolo AP; Sardão VA; Monteiro P; Gonçalves L; Providência LA; Palmeira CM; et al, 2004. Revista Portuguesa de Cardiologia. 1291 - 1298. 10. 23. 2004. http://europepmc.org/abstract/med/15641294 . Revista Portuguesa de Cardiologia

Vitamin E or coenzyme Q10 administration is not fully advantageous for heart mitochondrial function in diabetic goto kakizaki rats.

Oliveira PJ; Seica R; Santos DL; Rolo AP; Sardao VA; Ferreira FM; Palmeira CM; Santos MS; Moreno AJ, 2004. 2004. http://europepmc.org/abstract/med/16120365 . 10.1016/j.mito.2004.02.005 .

Carvedilol: relation between antioxidant activity and inhibition of the mitochondrial permeability transition.

Oliveira PJ; Esteves T; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/12712810 .

Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/12712811 .

Protection against post-ischemic mitochondrial injury in rat liver by silymarin or TUDC.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2003. 2003. http://europepmc.org/abstract/med/12850694 . 10.1016/S1386-6346(03)00108-6 .

Diabetes and mitochondrial bioenergetics: alterations with age.

Ferreira FM; Palmeira CM; Seiça R; Moreno AJ; Santos MS, 2003. 2003. http://europepmc.org/abstract/med/12898645 . 10.1002/jbt.10081 .

Chronic cholestasis and cardiac mitochondrial function in wistar rats: A model for cardiovascular alterations in chronic liver disease? | Colestase crónica e funçá~o mitocondrial cardíaca em ratos wistar: Um modelo para alterações cardiovasculares no contexto de doenças hepáticas crónicas?

Oliveira, P.J.; Rolo, A.P.; Seiça, R.; Santos, M.S.; Palmeira, C.M.; Moreno, A.J., 2003. Revista Portuguesa de Cardiologia. 67 - 75. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344951202&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Enhanced permeability transition explains the reduced calcium uptake in cardiac mitochondria from streptozotocin-induced diabetic rats.

Oliveira PJ; Seiça R; Coxito PM; Rolo AP; Palmeira CM; Santos MS; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/14623121 . 10.1016/S0014-5793(03)01233-X .

Mitochondrially mediated synergistic cell killing by bile acids.

Rolo AP; Palmeira CM; Wallace KB, 2003. 2003. http://europepmc.org/abstract/med/12527417 . 10.1016/S0925-4439(02)00224-7 .

Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with alpha-naphthyl-isothiocyanate (ANIT).

Palmeira CM; Ferreira FM; Rolo AP; Oliveira PJ; Santos MS; Moreno AJ; Cipriano MA; Martins MI; Seiça R, 2003. 2003. http://europepmc.org/abstract/med/12927374 . 10.1016/S0300-483X(03)00163-X .

Diabetes and mitochondrial oxidative stress: a study using heart mitochondria from the diabetic Goto-Kakizaki rat.

Santos DL; Palmeira CM; Seiça R; Dias J; Mesquita J; Moreno AJ; Santos MS, 2003. 2003. http://europepmc.org/abstract/med/12841358 . 10.1023/A:1023475022025 .

Diabetes induces metabolic adaptations in rat liver mitochondria: role of coenzyme Q and cardiolipin contents.

Ferreira FM; Seiça R; Oliveira PJ; Coxito PM; Moreno AJ; Palmeira CM; Santos MS, 2003. 2003. http://europepmc.org/abstract/med/14559118 . 10.1016/j.bbadis.2003.08.001 .

Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.

Ferreira FM; Oliveira PJ; Rolo AP; Santos MS; Moreno AJ; da Cunha MF; Seiça R; et al, 2003. Archives of Toxicology. 194 - 200. 4. 77. 2003. http://europepmc.org/abstract/med/12698234 . 10.1007/s00204-003-0441-3 . Archives of Toxicology

Carvedilol: Relation between antioxidant activity and inhibition of the mitochondrial permeability transition | Carvedilol: Relação entre a actividade antioxidante e inibição da transição de permeabilidade mitocondrial

Oliveira, P.J.; Esteves, T.; Rolo, A.P.; Monteiro, P.; Gonçalves, L.; Palmeira, C.M.; Moreno, A.J., 2003. Revista Portuguesa de Cardiologia. 55 - 62. 1. 22. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346034614&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Chenodeoxycholate induction of mitochondrial permeability transition pore is associated with increased membrane fluidity and cytochrome c release: protective role of carvedilol.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM, 2003. 2003. http://europepmc.org/abstract/med/16120330 . 10.1016/S1567-7249(03)00007-2 .

Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats.

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ; Oliveira, P.J.; et al, 2003. Journal of Investigative Medicine. 86 - 94. 2. 51. 2003. http://europepmc.org/abstract/med/12643513 . Journal of Investigative Medicine

Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies?

Oliveira PJ; Rolo AP; Seiça R; Santos MS; Palmeira CM; Moreno AJ, 2003. 2003. http://europepmc.org/abstract/med/12527405 . 10.1016/S0925-4439(02)00212-0 .

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase - What role in myocardial ischemia and reperfusion? | Impacto do carvedilol sobre o dano mitocondrial induzido por hipoxantina/xantina oxidase - Que papel na isquemia e reperfusão do miocárdio?

Oliveira, P.J.; Rolo, A.P.; Monteiro, P.; Conçalves, L.; Palmeira, C.M.; Moreno, A.J., 2002. Revista Portuguesa de Cardiologia. 1447 - 1455. 12. 21. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036998602&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Disruption of mitochondrial calcium homeostasis after chronic a-naphthylisothiocyanate administration: Relevance for cholestasis

Rolo, A.P.; Oliveira, P.J.; Seiça, R.; Santos, M.S.; Moreno, A.J.; Palmeira, C.M.; Rolo AP; et al, 2002. Journal of Investigative Medicine. 193 - 200. 3. 50. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036092085&partnerID=MN8TOARS . Journal of Investigative Medicine

Impact of diabetes on induction of the mitochondrial permeability transition.

Oliveira PJ; Rolo AP; Seiça R; Sardão V; Monteiro P; Gonçalves L; Providência L; et al, 2002. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology. 759 - 766. 6. 21. 2002. http://europepmc.org/abstract/med/12194377 . Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology

Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.

Rolo AP; Oliveira PJ; Seiça R; Santos MS; Moreno AJ; Palmeira CM, 2002. 2002. http://europepmc.org/abstract/med/12127259 . 10.1006/taap.2002.9434 .

Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?

Oliveira PJ; Rolo AP; Monteiro P; Gonçalves L; Palmeira CM; Moreno AJ, 2002. 2002. http://europepmc.org/abstract/med/12621918 .

Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.

Rolo AP; Palmeira CM; Wallace KB, 2002. 2002. http://europepmc.org/abstract/med/11814708 . 10.1016/S0378-4274(01)00464-7 .

Carvedilol reduces mitochondrial damage induced by hypoxanthine/xanthine oxidase: Relevance to hypoxia/reoxygenation injury

Oliveira, P.J.; Rolo, A.P.; Palmeira, C.M.; Moreno, A.J.M., 2001. Cardiovascular Toxicology. 205 - 213. 3. 1. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035750084&partnerID=MN8TOARS . 10.1385/CT:1:3:205 . Cardiovascular Toxicology

Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress

Santos, M.S.; Santos, D.L.; Palmeira, C.M.; Seiça, R.; Moreno, A.J.; Oliveira, C.R., 2001. Diabetes/Metabolism Research and Reviews. 223 - 230. 3. 17. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034944055&partnerID=MN8TOARS . 10.1002/dmrr.200 . Diabetes/Metabolism Research and Reviews

Decreased susceptibility of heart mitochondria from diabetic GK rats to mitochondrial permeability transition induced by calcium phosphate.

Oliveira PJ; Rolo AP; Seiça R; Palmeira CM; Santos MS; Moreno AJ; Oliveira, P.J.; et al, 2001. Bioscience Reports. 45 - 53. 1. 21. 2001. http://europepmc.org/abstract/med/11508693 . 10.1023/a:1010482017540 . Bioscience Reports

Enhanced mitochondrial testicular antioxidant capacity in Goto-Kakizaki diabetic rats: Role of coenzyme Q

Palmeira, C.M.; Santos, D.L.; Seiça, R.; Moreno, A.J.; Santos, M.S.; Palmeira CM; Santos DL; et al, 2001. American Journal of Physiology - Cell Physiology. 3 50-3. 281. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034838234&partnerID=MN8TOARS . American Journal of Physiology - Cell Physiology

Carvedilol in heart mitochondria - Protonophore or opener of the mitochondrial K<inf>ATP</inf> channels?

Oliveira, P.J.; Rolo, A.P.; Sardão, V.A.; Coxito, P.M.; Palmeira, C.M.; Moreno, A.J.M., 2001. Life Sciences. 123 - 132. 2. 69. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035371154&partnerID=MN8TOARS . 10.1016/S0024-3205(01)01109-2 . Life Sciences

Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore

Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M., 2001. Biochemical Pharmacology. 1449 - 1454. 11. 61. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035370544&partnerID=MN8TOARS . 10.1016/S0006-2952(01)00620-7 . Biochemical Pharmacology

Inhibitory effect of carvedilol in the high-conductance state of the mitochondrial permeability transition pore

Oliveira, P.J.; Coxito, P.M.; Rolo, A.P.; Santos, D.L.; Palmeira, C.M.; Moreno, A.J.M., 2001. European Journal of Pharmacology. 231 - 237. 3. 412. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035793307&partnerID=MN8TOARS . 10.1016/S0014-2999(01)00745-2 . European Journal of Pharmacology

Doxorubicin-induced persistent oxidative stress to cardiac myocytes

Zhou, S.; Palmeira, C.M.; Wallace, K.B., 2001. Toxicology Letters. 151 - 157. 3. 121. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035912594&partnerID=MN8TOARS . 10.1016/S0378-4274(01)00329-0 . Toxicology Letters

Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria

Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M., 2001. Bioscience Reports. 73 - 80. 1. 21. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034899577&partnerID=MN8TOARS . 10.1023/A:1010438202519 . Bioscience Reports

Cholestasis and mitochondrial dysfunction: A review

Rolo, A.P.; Palmeira, C.M., 2000. Toxic Substance Mechanisms. 83 - 98. 2. 19. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034458883&partnerID=MN8TOARS . 10.1080/10769180052008878 . Toxic Substance Mechanisms

Induction of the mitochondrial permeability transition in vitro by short-chain carboxylic acids

Palmeira, C.M.; Rana, M.I.; Frederick, C.B.; Wallace, K.B., 2000. Biochemical and Biophysical Research Communications. 431 - 435. 2. 272. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034616658&partnerID=MN8TOARS . 10.1006/bbrc.2000.2797 . Biochemical and Biophysical Research Communications

Bile acids affect liver mitochondrial bioenergetics: possible relevance for cholestasis therapy.

Rolo AP; Oliveira PJ; Moreno AJ; Palmeira CM; Rolo, A.P.; Oliveira, P.J.; Moreno, A.J.M.; Palmeira, C.M., 2000. Toxicological Sciences. 177 - 185. 1. 57. 2000. http://europepmc.org/abstract/med/10966524 . 10.1093/toxsci/57.1.177 . Toxicological Sciences

Herbicide-induced mitochondrial and cellular liver toxicity: A review of paraquat, dinoseb, and 2,4-D effects

Palmeira, C.M., 1999. Toxic Substance Mechanisms. 187 - 204. 4. 18. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033457940&partnerID=MN8TOARS . 10.1080/107691899229070 . Toxic Substance Mechanisms

Alterations of liver mitochondrial bioenergetics in diabetic Goto- Kakizaki rats

Ferreira, F.M.L.; Palmeira, C.M.; Seiça, R.; Santos, M.S., 1999. Metabolism: Clinical and Experimental. 1115 - 1119. 9. 48. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032857256&partnerID=MN8TOARS . 10.1016/S0026-0495(99)90124-5 . Metabolism: Clinical and Experimental

Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration

Serrano, J.; Palmeira, C.M.; Kuehl, D.W.; Wallace, K.B., 1999. Biochimica et Biophysica Acta - Bioenergetics. 201 - 205. 1. 1411. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032961434&partnerID=MN8TOARS . 10.1016/S0005-2728(99)00011-0 . Biochimica et Biophysica Acta - Bioenergetics

Decreased susceptibility to lipid peroxidation of Goto-Kakizaki rats: Relationship to mitochondrial antioxidant capacity

Ferreira, F.M.L.; Palmeira, C.M.; Matos, M.J.; Seiç, R.; Santos, M.S., 1999. Life Sciences. 1013 - 1025. 10. 65. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033618489&partnerID=MN8TOARS . 10.1016/S0024-3205(99)00332-X . Life Sciences

Higher efficiency of the liver phosphorylative system in diabetic Goto-Kakizaki (GK) rats

Palmeira, C.M.; Ferreira, F.M.L.; Santos, D.L.; Ceiça, R.; Suzuki, K.-I.; Santos, M.S., 1999. FEBS Letters. 103 - 106. 2. 458. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032842698&partnerID=MN8TOARS . 10.1016/S0014-5793(99)01144-8 . FEBS Letters

Age-related alterations in liver mitochondrial bioenergetics of diabetic Goto-Kakizaki rats.

Ferreira FM; Seiça R; Santos MS; Palmeira CM; Ferreira, F.M.L.; Seiça, R.; Santos, M.S.; Palmeira, C.M., 1999. Acta Diabetologica. 173 - 177. 4. 36. 1999. http://europepmc.org/abstract/med/10664324 . 10.1007/s005920050163 . Acta Diabetologica

Ischemic heart disease: The role of mitochondria - Carvedilol prevents lipid peroxidation of mitochondrial membranes

Moreno, A.J.M.; Santos, D.J.S.L.; Palmeira, C.M.; Moreno AJ; Santos DJ; Palmeira CM, 1998. Revista Portuguesa de Cardiologia. 63 - 77. SUPPL. 2. 17. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031759966&partnerID=MN8TOARS . Revista Portuguesa de Cardiologia

Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro

Custodio, J.B.A.; Palmeira, C.M.; Moreno, A.J.; Wallace, K.B., 1998. Toxicological Sciences. 19 - 27. 1. 43. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031831694&partnerID=MN8TOARS . 10.1006/toxs.1998.2448 . Toxicological Sciences

Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones

Palmeira, C.M.; Wallace, K.B., 1997. Toxicology and Applied Pharmacology. 338 - 347. 2. 143. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030932708&partnerID=MN8TOARS . 10.1006/taap.1996.8099 . Toxicology and Applied Pharmacology

Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin

Palmeira, C.M.; Serrano, J.; Kuehl, D.W.; Wallace, K.B., 1997. Biochimica et Biophysica Acta - Bioenergetics. 101 - 106. 2. 1321. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030880285&partnerID=MN8TOARS . 10.1016/S0005-2728(97)00055-8 . Biochimica et Biophysica Acta - Bioenergetics

Mercuric chloride toxicity in rat liver mitochondria and isolated hepatocytes

Palmeira, C.M.; Madeira, V.M.C., 1997. Environmental Toxicology and Pharmacology. 229 - 235. 3. 3. 1997. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030758726&partnerID=MN8TOARS . 10.1016/S1382-6689(97)00018-5 . Environmental Toxicology and Pharmacology

Continuous monitoring of mitochondrial membrane potential in hepatocyte cell suspensions

Palmeira, C.M.; Moreno, A.J.M.; Madeira, V.M.C.; Wallace, K.B., 1996. Journal of Pharmacological and Toxicological Methods. 35 - 43. 1. 35. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029925338&partnerID=MN8TOARS . 10.1016/1056-8719(95)00131-X . Journal of Pharmacological and Toxicological Methods

Determination of 8-hydroxydeoxyguanosine in biological tissue by liquid chromatography/electrospray ionization-mass spectrometry/mass spectrometry

Serrano, J.; Palmeira, C.M.; Wallace, K.B.; Kuehl, D.W., 1996. Rapid Communications in Mass Spectrometry. 1789 - 1791. 14. 10. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030478989&partnerID=MN8TOARS . 10.1002/(SICI)1097-0231(199611)10:14<1789::AID-RCM752>3.0.CO;2-6 . Rapid Communications in Mass Spectrometry

Thiols metabolism is altered by the herbicides paraquat, dinoseb and 2,4-D: A study in isolated hepatocytes

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1995. Toxicology Letters. 115 - 123. 2-3. 81. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029590153&partnerID=MN8TOARS . 10.1016/0378-4274(95)03414-5 . Toxicology Letters

Effects of paraquat, dinoseb and 2,4-D on intracellular calcium and on vasopressin-induced calcium mobilization in isolated hepatocytes

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1995. Archives of Toxicology. 460 - 466. 7. 69. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029054234&partnerID=MN8TOARS . 10.1007/s002040050199 . Archives of Toxicology

Mitochondrial bioenergetics is affected by the herbicide paraquat

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1995. Biochimica et Biophysica Acta - Bioenergetics. 187 - 192. 2. 1229. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028961733&partnerID=MN8TOARS . 10.1016/0005-2728(94)00202-G . Biochimica et Biophysica Acta - Bioenergetics

Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb and 2,4-D

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1994. Archives of Toxicology. 24 - 31. 1. 68. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028009773&partnerID=MN8TOARS . 10.1007/s002040050025 . Archives of Toxicology

Interactions of herbicides 2,4-D and dinoseb with liver mitochondrial bioenergetics

Palmeira, C.M.; Moreno, A.J.; Madeira, V.M.C., 1994. Toxicology and Applied Pharmacology. 50 - 57. 1. 127. 1994. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028146853&partnerID=MN8TOARS . 10.1006/taap.1994.1138 . Toxicology and Applied Pharmacology

Membrane lipid peroxidation induces changes in ¿-[3H]aminobutyric acid transport and calcium uptake by synaptosomes

Palmeira, C.M.; Santos, M.S.; Carvalho, A.P.; Oliveira, C.R.; Palmeira CM; Santos MS; Carvalho AP; Oliveira CR, 1993. Brain Research. 117 - 123. 1-2. 609. 1993. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027309463&partnerID=MN8TOARS . 10.1016/0006-8993(93)90863-I . Brain Research

Partitioning and membrane disordering effects of dopamine antagonists: Influence of lipid peroxidation, temperature, and drug concentration

Palmeira, C.M.; Oliveira, C.R., 1992. Archives of Biochemistry and Biophysics. 161 - 171. 1. 295. 1992. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026729101&partnerID=MN8TOARS . 10.1016/0003-9861(92)90502-N . Archives of Biochemistry and Biophysics