Armindo Salvador

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Researcher

Publications

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Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.

Intra-dimer cooperativity between the active site cysteines during the oxidation of peroxiredoxin 2

Peskin, Alexander V.; Meotti, Flávia C.; de Souza, Luiz F.; Anderson, Robert F.; Winterbourn, Christine C.; Salvador, Armindo, Free Radical Biology and Medicine. 115 - 125. 158. 2020. http://dx.doi.org/10.1016/j.freeradbiomed.2020.07.007 . 10.1016/j.freeradbiomed.2020.07.007 . published Free Radical Biology and Medicine

Quantitative Assessment of Methods Used To Obtain Rate Constants from Molecular Dynamics Simulations—Translocation of Cholesterol across Lipid Bilayers

Filipe, Hugo A. L.; Javanainen, Matti; Salvador, Armindo; Galvão, Adelino M.; Vattulainen, Ilpo; Loura, Luís M. S.; Moreno, Maria João, Journal of Chemical Theory and Computation. 3840 - 3848. 7. 14. 2018. http://dx.doi.org/10.1021/acs.jctc.8b00150 . 10.1021/acs.jctc.8b00150 . published Journal of Chemical Theory and Computation

Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types

Selvaggio, G.; Coelho, P.M.B.M.; Salvador, A., Redox Biology. 297 - 315. 15. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85039867388&partnerID=MN8TOARS . 10.1016/j.redox.2017.12.008 . Redox Biology

Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling

Travasso, R.D.M.; Sampaio dos Aidos, F.; Bayani, A.; Abranches, P.; Salvador, A., Redox Biology. 233 - 245. 12. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014574052&partnerID=MN8TOARS . 10.1016/j.redox.2017.01.003 . Redox Biology

Mass Isotopomer Analysis of Nucleosides Isolated from RNA and DNA Using GC/MS

Miranda-Santos, Ines; Gramacho, Silvia; Pineiro, Marta; Martinez-Gomez, Karla; Fritz, Michel; Hollemeyer, Klaus; Salvador, Armindo; Heinzle, Elmar, Analytical Chemistry. 617 - 623. 1. 87. 2015. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000347590400063&KeyUID=WOS:000347590400063 . 10.1021/ac503305w . Analytical Chemistry

Beyond Overton’s Rule: Quantitative Modeling of Passive Permeation through Tight Cell Monolayers

Filipe, H. A. L.; Salvador, A.; Silvestre, J. M.; Vaz, W. L. C.; Moreno, M. J., Molecular Pharmaceutics. 3696 - 3706. 10. 11. 2014. http://dx.doi.org/10.1021/mp500437e . 10.1021/mp500437e . published Molecular Pharmaceutics

Homeostasis of free cholesterol in the blood: A preliminary evaluation and modeling of its passive transport

Estronca, L.M.B.B.; Filipe, H.A.L.; Salvador, A.; Moreno, M.J.; Vaz, W.L.C., Journal of Lipid Research. 1033 - 1043. 6. 55. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901660412&partnerID=MN8TOARS . 10.1194/jlr.M043067 . Journal of Lipid Research

Hydrogen peroxide metabolism and sensing in human erythrocytes: A validated kinetic model and reappraisal of the role of peroxiredoxin II

Benfeitas, R.; Selvaggio, G.; Antunes, F.; Coelho, P.M.B.M.; Salvador, A., Free Radical Biology and Medicine. 35 - 49. 74. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904329372&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2014.06.007 . Free Radical Biology and Medicine

Relating mutant genotype to phenotype via quantitative behavior of the NADPH redox cycle in human erythrocytes

Coelho, P.M.B.M.; Salvador, A.; Savageau, M.A., PLoS ONE. 9. 5. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77958545833&partnerID=MN8TOARS . 10.1371/journal.pone.0013031 . PLoS ONE

Phenotypes and tolerances in the design space of biochemical systems

Savageau, M.A.; Coelho, P.M.B.M.; Fasani, R.A.; Tolla, D.A.; Salvador, A., Proceedings of the National Academy of Sciences of the United States of America. 6435 - 6440. 16. 106. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-66149108427&partnerID=MN8TOARS . 10.1073/pnas.0809869106 . Proceedings of the National Academy of Sciences of the United States of America

Quantifying global tolerance of biochemical systems: Design implications for moiety-transfer cycles

Coelho, P.M.B.M.; Salvador, A.; Savageau, M.A., PLoS Computational Biology. 3. 5. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-63549119474&partnerID=MN8TOARS . 10.1371/journal.pcbi.1000319 . PLoS Computational Biology

Evolution of enzymes in a series is driven by dissimilar functional demands

Salvador, A.; Savageau, M.A., Proceedings of the National Academy of Sciences of the United States of America. 2226 - 2231. 7. 103. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33144458377&partnerID=MN8TOARS . 10.1073/pnas.0510776103 . Proceedings of the National Academy of Sciences of the United States of America

Tools for kinetic modeling of biochemical networks

Alves, R.; Antunes, F.; Salvador, A., Nature Biotechnology. 667 - 672. 6. 24. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33745075591&partnerID=MN8TOARS . 10.1038/nbt0606-667 . Nature Biotechnology

Why does superoxide dismutase overexpression often increase hydrogen peroxide concentrations? An alternative explanation

Gardner, R.; Moradas-Ferreira, P.; Salvador, A., Journal of Theoretical Biology. 798 - 800. 3. 242. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747879504&partnerID=MN8TOARS . 10.1016/j.jtbi.2006.04.007 . Journal of Theoretical Biology

Quantitative evolutionary design of glucose 6-phosphate dehydrogenase expression in human erythrocytes

Salvador, A.; Savageau, M.A., Proceedings of the National Academy of Sciences of the United States of America. 14463 - 14468. SUPPL. 2. 100. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0345060788&partnerID=MN8TOARS . 10.1073/pnas.2335687100 . Proceedings of the National Academy of Sciences of the United States of America

Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation

Gardner, R.; Salvador, A.; Moradas-Ferreira, P., Free Radical Biology and Medicine. 1351 - 1357. 12. 32. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037096203&partnerID=MN8TOARS . 10.1016/S0891-5849(02)00861-4 . Free Radical Biology and Medicine

Hydroperoxyl, superoxide and pH gradients in the mitochondrial matrix: A theoretical assessment

Salvador, A.; Sousa, J.; Pinto, R.E., Free Radical Biology and Medicine. 1208 - 1215. 10. 31. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035890104&partnerID=MN8TOARS . 10.1016/S0891-5849(01)00707-9 . Free Radical Biology and Medicine

Synergism analysis of biochemical systems. II. Tensor formulation and treatment of stoichiometric constraints

Salvador, A., Mathematical Biosciences. 131 - 158. 2. 163. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034092624&partnerID=MN8TOARS . 10.1016/S0025-5564(99)00057-7 . Mathematical Biosciences

Synergism analysis of biochemical systems. I. Conceptual framework

Salvador, A., Mathematical Biosciences. 105 - 129. 2. 163. 2000. 10.1016/s0025-5564(99)00056-5 . Mathematical Biosciences

Lipid peroxidation in mitochondrial inner membranes. I. An integrative kinetic model

Antunes, F.; Salvador, A.; Marinho, H.S.; Alves, R.; Pinto, R.E., Free Radical Biology and Medicine. 917 - 943. 7. 21. 1996. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029908304&partnerID=MN8TOARS . 10.1016/S0891-5849(96)00185-2 . Free Radical Biology and Medicine

PHGPx and phospholipase A2/GPx: Comparative importance on the reduction of hydroperoxides in rat liver mitochondria

Antunes, F.; Salvador, A.; Pinto, R.E., Free Radical Biology and Medicine. 669 - 677. 5. 19. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028991435&partnerID=MN8TOARS . 10.1016/0891-5849(95)00040-5 . Free Radical Biology and Medicine

Kinetic modelling of in vitro lipid peroxidation experiments--'low level' validation of a model of in vivo lipid peroxidation.

Salvador, A.; Antunes, F.; Pinto, R.E., Free radical research. 151 - 172. 2. 23. 1995. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029355440&partnerID=MN8TOARS . 10.3109/10715769509064029 . Free radical research

All projects

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Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.

2016/07 - 2019/06

Unraveling the rules of passive permeation through the bloodbrain barrier

PTDC/DTP-FTO/ 2784/2014

Supervisor

Universidade de Coimbra Centro de Química de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2016/07 - 2019/06

Relationship between adenosine and chromosomal instability: a new perspective to understand the oncogenic mechanism in glioblastoma

PTDC/BIM-ONC/ 7121/2014

Supervisor

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2012/04 - 2015/09

Finding the naturally evolved design principles of prevalent metabolic circuits

Provided by PTCRIS: 119657

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Faculdade de Ciencias e Tecnologia; Universidade do Minho

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2010/02 - 2013/02

Derivative-Free Optimization: Future Challenges and New Applications

Provided by PTCRIS: 98214

Supervisor

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2008/01 - 2011/12

Reconstruction and systems analysis of the reaction networks of reactive oxygen, nitrogen and sulfur species in representative physiological systems

Provided by PTCRIS: 70523

Principal investigator

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2007/07 - 2010/09

Quantitative Modeling of Passive Trancytotic Diffusion of Amphiphilic Molecules Across the Blood-Brain Barrier

Provided by PTCRIS: 69072

Supervisor

Universidade de Coimbra Centro de Química de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia, I.P.

2007/01/01 - 2008/12/31

Quantitative evolutionary principles in yeast stress response

E6-07

Principal investigator

Conselho de Reitores das Universidades Portuguesas

Funders: Conselho de Reitores das Universidades Portuguesas

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