Carlos Filipe Pereira

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Researcher

Is immunotherapy the holy grail for pancreatic cancer?

Andersson, R.; Pereira, C.-F.; Bauden, M.; Ansari, D., Immunotherapy. 1435 - 1438. 17. 11. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85076450369&partnerID=MN8TOARS . 10.2217/imt-2019-0164 . Immunotherapy

Understanding and Modulating Immunity With Cell Reprogramming

Pires, C.F.; Rosa, F.F.; Kurochkin, I.; Pereira, C.-F., Frontiers in Immunology. 10. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85077260284&partnerID=MN8TOARS . 10.3389/fimmu.2019.02809 . Frontiers in Immunology

Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors

Silvério-Alves, R.; Gomes, A.M.; Kurochkin, I.; Moore, K.A.; Pereira, C.-F., Journal of visualized experiments : JoVE. 153. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075191300&partnerID=MN8TOARS . 10.3791/60112 . Journal of visualized experiments : JoVE

Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture

Daniel, M.G.; Sachs, D.; Bernitz, J.M.; Fstkchyan, Y.; Rapp, K.; Satija, N.; Law, K.; et al, FEBS Letters. 3266 - 3287. 23. 593. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85074051202&partnerID=MN8TOARS . 10.1002/1873-3468.13621 . FEBS Letters

Ihor R. Lemischka (1953-2017)

Ivanova, Natalia; Pereira, Carlos-Filipe; Lee, Dung-Fang, Cell Stem Cell. 16 - +. 1. 22. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000419306500008&KeyUID=WOS:000419306500008 . 10.1016/j.stem.2017.12.015 . Cell Stem Cell

Ihor R. Lemischka (1953-2017) Obituary

Ivanova, Natalia; Pereira, Carlos-Filipe; Lee, Dung-Fang, Cell. 1 - +. 1-2. 172. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000419840100001&KeyUID=WOS:000419840100001 . 10.1016/j.cell.2017.12.028 . Cell

Direct reprogramming of fibroblasts into antigen-presenting dendritic cells

Rosa, Fabio F.; Pires, Cristiana F.; Kurochkin, Ilia; Ferreira, Alexandra G.; Gomes, Andreia M.; Palma, Luis G.; Shaiv, Kritika; et al, Science Immunology. 30. 3. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000452571800002&KeyUID=WOS:000452571800002 . 10.1126/sciimmunol.aau4292 . Science Immunology

Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

Gomes, Andreia M.; Kurochkin, Ilia; Chang, Betty; Daniel, Michael; Law, Kenneth; Satija, Namita; Lachmann, Alexander; et al, Cell Reports. 2821 - +. 10. 25. 2018. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000452894600018&KeyUID=WOS:000452894600018 . 10.1016/j.celrep.2018.11.032 . Cell Reports

INDUCTION OF HEMOGENIC REPROGRAMMING IN HUMAN FIBROBLASTS

Gomes, A.; Pereira, C. -F.; Chang, B.; Kurochkin, I.; Daniel, M.; Law, K.; Satija, N.; et al, Haematologica. 102. 2017. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000404127006340&KeyUID=WOS:000404127006340 . Haematologica

High-throughput identification of small molecules that affect human embryonic vascular development

Vazão, H.; Rosa, S.; Barata, T.; Costa, R.; Pitrez, P.R.; Honório, I.; De Vries, M.R.; et al, Proceedings of the National Academy of Sciences of the United States of America. E3022 - E3031. 15. 114. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85035214278&partnerID=MN8TOARS . 10.1073/pnas.1617451114 . Proceedings of the National Academy of Sciences of the United States of America

Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate

Freire, A.G.; Waghray, A.; Soares-da-Silva, F.; Resende, T.P.; Lee, D.-F.; Pereira, C.-F.; Nascimento, D.S.; Lemischka, I.R.; Pinto-do-Ó, P., Stem Cell Reports. 136 - 148. 1. 9. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021126795&partnerID=MN8TOARS . 10.1016/j.stemcr.2017.05.025 . Stem Cell Reports

Reprogramming mouse embryonic fibroblasts with transcription factors to induce a hemogenic program

Daniel, M.G.; Pereira, C.-F.; Bernitz, J.M.; Lemischka, I.R.; Moore, K., Journal of Visualized Experiments. 118. 2016. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015946426&partnerID=MN8TOARS . 10.3791/54372 . Journal of Visualized Experiments

The stem cell niche finds its true north

Agnete Kirkeby; Thomas Perlmann; Carlos-Filipe Pereira, Development. 2877 - 2881. 16. 143. 2016. https://doi.org/10.1242/dev.140095 . 10.1242/dev.140095 . Development

Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells

Pereira, C.-F.; Chang, B.; Gomes, A.; Bernitz, J.; Papatsenko, D.; Niu, X.; Swiers, G.; et al, Developmental Cell. 525 - 539. 5. 36. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959312876&partnerID=MN8TOARS . 10.1016/j.devcel.2016.02.011 . Developmental Cell

MECHANISMS UNDERLYING HUMAN HEMOGENIC REPROGRAMMING

Gomes, Andreia; Pereira, Carlos-Filipe; Papatsenko, Dmitri; Moore, Kateri Ann; Lemischka, Ihor, Experimental Hematology. S75 - S76. 9. 44. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000382184600129&KeyUID=WOS:000382184600129 . 10.1016/j.exphem.2016.06.144 . Experimental Hematology

ZERO FOOTPRINT INDUCTION OF HUMAN HEMOGENESIS TO STUDY PATHOLOGIC DEVELOPMENTAL HEMATOPOIESIS IN FANCONI ANEMIA

Daniel, Michael; Fstkchyan, Yesai; Gomes, Andreia; Pereira, Carlos-Filipe; Lemischka, Ihor; Moore, Kateri Ann, Experimental Hematology. S65 - S65. 9. 44. 2016. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000382184600098&KeyUID=WOS:000382184600098 . 10.1016/j.exphem.2016.06.112 . Experimental Hematology

Making a Hematopoietic Stem Cell.

Daniel MG; Pereira CF; Lemischka IR; Moore KA, 2015. http://europepmc.org/abstract/med/26526106 . 10.1016/j.tcb.2015.10.002 .

Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm

Waghray, A.; Saiz, N.; Jayaprakash, A.D.; Freire, A.G.; Papatsenko, D.; Pereira, C.-F.; Lee, D.-F.; et al, Stem Cell Reports. 97 - 110. 1. 5. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937523983&partnerID=MN8TOARS . 10.1016/j.stemcr.2015.05.009 . Stem Cell Reports

'From blood to blood': De-differentiation of hematopoietic progenitors to stem cells

Pereira, C.-F.; Lemischka, I.R.; Moore, K., EMBO Journal. 1511 - 1513. 14. 33. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84904561142&partnerID=MN8TOARS . 10.15252/embj.201488980 . EMBO Journal

"There will be blood" from fibroblasts

Pereira, C.-F.; Lemischka, I.R.; Moore, K., Cell Cycle. 335 - 336. 3. 13. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896884486&partnerID=MN8TOARS . 10.4161/cc.27507 . Cell Cycle

DIRECT CONVERSION FROM MOUSE FIBROBLASTS INFORMS THE IDENTIFICATION OF HEMOGENIC PRECURSOR CELLS IN VIVO

Pereira, Carlos-Filipe; Chang, Betty; Niu, Xiaohong; Gomes, Andreia; Swiers, Gemma; Azzoni, Emanuele; Schaniel, Christoph; et al, Experimental Hematology. S55 - S55. 8. 42. 2014. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000340344300196&KeyUID=WOS:000340344300196 . Experimental Hematology

Induction of a hemogenic program in mouse fibroblasts.

Pereira, Carlos-Filipe; Chang, Betty; Qiu, Jiajing; Niu, Xiaohong; Papatsenko, Dmitri; Hendry, Caroline E; Clark, Neil R; et al, Cell stem cell. 205 - 18. 2. 13. 2013. 10.1016/j.stem.2013.05.024 . Cell stem cell

Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling

Lee, Dung-Fang; Su, Jie; Ang, Yen-Sin; Carvajal-Vergara, Xonia; Mulero-Navarro, Sonia; Pereira, Carlos F.; Gingold, Julian; et al, Cell Stem Cell. 179 - 194. 2. 11. 2012. 10.1016/j.stem.2012.05.020 . Cell Stem Cell

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

Fidalgo, Miguel; Faiola, Francesco; Pereira, Carlos-Filipe; Ding, Junjun; Saunders, Arven; Gingold, Julian; Schaniel, Christoph; et al, Proceedings of the National Academy of Sciences of the United States of America. 16202 - 16207. 40. 109. 2012. 10.1073/pnas.1208533109 . Proceedings of the National Academy of Sciences of the United States of America

Using heterokaryons to understand pluripotency and reprogramming

Piccolo, Francesco M.; Pereira, Carlos F.; Cantone, Irene; Brown, Karen; Tsubouchi, Tomomi; Soza-Ried, Jorge; Merkenschlager, Matthias; Fisher, Amanda G., Philosophical Transactions of the Royal Society B-Biological Sciences. 2260 - 2265. 1575. 366. 2011. 10.1098/rstb.2011.0004 . Philosophical Transactions of the Royal Society B-Biological Sciences

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators

Landeira, David; Sauer, Stephan; Poot, Raymond; Dvorkina, Maria; Mazzarella, Luca; Jorgensen, Helle F.; Pereira, C. Filipe; et al, Nature Cell Biology. 618 - U214. 6. 12. 2010. 10.1038/ncb2065 . Nature Cell Biology

Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo

Santos, Joana; Pereira, C. Filipe; Di-Gregorio, Aida; Spruce, Thomas; Alder, Olivia; Rodriguez, Tristan; Azuara, Veronique; Merkenschlager, Matthias; Fisher, Amanda G., Epigenetics & Chromatin. 3. 2010. 10.1186/1756-8935-3-1 . Epigenetics & Chromatin

Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2

Kanhere, Aditi; Viiri, Keijo; Araujo, Carla C.; Rasaiyaah, Jane; Bouwman, Russell D.; Whyte, Warren A.; Pereira, C. Filipe; et al, Molecular Cell. 675 - 688. 5. 38. 2010. 10.1016/j.molcel.2010.03.019 . Molecular Cell

ESCs Require PRC2 to Direct the Successful Reprogramming of Differentiated Cells toward Pluripotency

Pereira, Carlos F.; Piccolo, Francesco M.; Tsubouchi, Tomomi; Sauer, Stephan; Ryan, Natalie K.; Bruno, Ludovica; Landeira, David; et al, Cell Stem Cell. 547 - 556. 6. 6. 2010. 10.1016/j.stem.2010.04.013 . Cell Stem Cell

CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression.

Schnetz, M.P.; Handoko, L.; Akhtar-Zaidi, B.; Bartels, C.F.; Pereira, C.F.; Fisher, A.G.; Adams, D.J.; et al, PLoS genetics. 7. 6. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952538205&partnerID=MN8TOARS . PLoS genetics

Heterokaryon-based reprogramming for pluripotency

Pereira, C.F.; Fisher, A.G., Current Protocols in Stem Cell Biology. SUPPL. 9. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-65149087887&partnerID=MN8TOARS . 10.1002/9780470151808.sc04b01s9 . Current Protocols in Stem Cell Biology

REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells

Jorgensen, Helle F.; Terry, Anna; Beretta, Chiara; Pereira, C. Filipe; Leleu, Marion; Chen, Zhou-Feng; Kelly, Claire; Merkenschlager, Matthias; Fisher, Amanda G., Development. 715 - 721. 5. 136. 2009. 10.1242/dev.028548 . Development

Senescence impairs successful reprogramming to pluripotent stem cells

Banito, Ana; Rashid, Sheikh T.; Acosta, Juan Carlos; Li, SiDe; Pereira, Carlos F.; Geti, Imbisaat; Pinho, Sandra; et al, Genes & Development. 2134 - 2139. 18. 23. 2009. 10.1101/gad.1811609 . Genes & Development

Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression

Savarese, Fabio; Davila, Amparo; Nechanitzky, Robert; De La Rosa-Velazquez, Inti; Pereira, Carlos F.; Engelke, Rudolf; Takahashi, Keiko; et al, Genes & Development. 2625 - 2638. 22. 23. 2009. 10.1101/gad.1815709 . Genes & Development

Hepatocytes and IL-15: A Favorable Microenvironment for T Cell Survival and CD8(+) T Cell Differentiation

Correia, Margareta P.; Cardoso, Elsa M.; Pereira, Carlos F.; Neves, Rui; Uhrberg, Markus; Arosa, Fernando A., Journal of Immunology. 6149 - 6159. 10. 182. 2009. 10.4049/jimmunol.0802470 . Journal of Immunology

Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

Pereira, Carlos F.; Terranova, Remi; Ryan, Natalie K.; Santos, Joana; Morris, Kelly J.; Cui, Wei; Merkenschlager, Matthias; Fisher, Amanda G., Plos Genetics. 9. 4. 2008. 10.1371/journal.pgen.1000170 . Plos Genetics

Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2

Nunes, R.J.; Castro, M.A.A.; Gonçalves, C.M.; Bamberger, M.; Pereira, C.F.; Bismuth, G.; Carmo, A.M., Journal of Immunology. 988 - 997. 2. 180. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-40449133966&partnerID=MN8TOARS . Journal of Immunology

Protein interactions between CD2 and Lck are required for the lipid raft distribution of CD2

Nunes, R.J.; Castro, M.A.A.; Gonçalves, C.M.; Bamberger, M.; Pereira, C.F.; Bismuth, G.; Carmo, A.M., Journal of Immunology. 988 - 997. 2. 180. 2008. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252290000036&KeyUID=WOS:000252290000036 . 10.4049/jimmunol.180.2.988 . Journal of Immunology

Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming

Terranova, R.; Pereira, C. F.; Du Roure, C.; Merkenschlager, M.; Fisher, A. G., Journal of Cell Science. 2065 - 2072. 10. 119. 2006. 10.1242/jcs.02945 . Journal of Cell Science

Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading

Cabrita, M.; Pereira, C. F.; Rodrigues, P.; Cardoso, E. M.; Arosa, F. A., Febs Journal. 152 - 165. 1. 272. 2005. 10.1111/j.1432-1033.2004.04387.x . Febs Journal

Red blood cells as modulators of T cell growth and survival

Arosa, F. A.; Pereira, C. F.; Fonseca, A. M., Current Pharmaceutical Design. 191 - 201. 2. 10. 2004. 10.2174/1381612043453432 . Current Pharmaceutical Design

Red blood cells upregulate cytoprotective proteins and the labile iron pool in dividing human T cells despite a reduction in oxidative stress

Fonseca, A.M.; Pereira, C.F.; Porto, G.; Arosa, F.A., Free Radical Biology and Medicine. 1404 - 1416. 11. 35. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344875071&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2003.08.011 . Free Radical Biology and Medicine

Red blood cells promote survival and cell cycle progression of human peripheral blood T cells independently of CD58/LFA-3 and heme compounds

Fonseca, A.M.; Pereira, C.F.; Porto, G.; Arosa, F.A., Cellular Immunology. 17 - 28. 1. 224. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0142169441&partnerID=MN8TOARS . 10.1016/S0008-8749(03)00170-9 . Cellular Immunology

Red blood cells promote survival and cell cycle progression of human peripheral blood T cells independently of CD58/LFA-3 and heme compounds

Fonseca, A. M.; Pereira, C. F.; Porto, G.; Arosa, F. A., Cellular Immunology. 17 - 28. 1. 224. 2003. 10.1016/s0008-8749(03)00170-9 . Cellular Immunology

All projects

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Information of exclusive responsibility of the researcher 28-11-2021 , from platform CIÊNCIAVITAE.

2021/01/01 - 2026/12/31

Inducing antigen presentation in tumor cells with direct cell reprogramming

2020-00615

Principal investigator

Funders: Vetenskapsradet

2021/01/01 - 2023/12/31

DiverDC: Understanding dendritic cell diversity with cell reprogramming

PTDC/MED-IMU/4520/2020

Principal investigator

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

2020/03/01 - 2021/02/28

Dendritic Cell Therapy

0053036

Principal investigator

Lund Universitet Institutionen för laboratoriemedicin Malmö

Funders: Novo Nordisk Fonden

2020/06/01 - 2025/05/31

Harnessing dendritic cell reprogramming for cancer immunotherapy

866448

Principal investigator

Lunds Universitet

Funders: European Research Council

2020/06/01 - 2021/05/31

Inducing NK cells with direct cell reprogramming

0062919

Principal investigator

Lund Universitet Institutionen för laboratoriemedicin Malmö

2019/10/01 - 2022/09/30

Generating T Cells from Fibroblasts and Mesenchymal Stem Cells

AUTO-PEREIRA

Principal investigator

Lunds Universitet

Funders: Autolus Ltd

2019/09/01 - 2021/08/31

Elucidating the Mechanisms of Hematopoietic Reprogramming.

194-694

Principal investigator

Lunds Universitet

Funders: Stiftelsen Olle Engkvist Byggmästare

2019/09/01 - 2020/08/31

Mass spectrometry-based immunopeptidomic profiling in stem cells, disease and reprogramming.

StemTherapy Methods Grant.

Lund Universitet Institutionen för laboratoriemedicin Malmö

2019/01 - 2020/12/31

Generating Dendritic Cells by Direct Cell Reprogramming

2018-02442

Principal investigator

Lunds Universitet

Funders: Vetenskapsradet

2018/07/01 - 2021/03/31

ReProgram: Reconstructing the Program of Cancer Stem Cells

POCI-01-0145-FEDER-029017

Principal investigator

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

2018/01 - 2018/12

Generating Dendritic Cells by Direct Reprogramming

20180864

Principal investigator

Lunds Universitet

Funders: Crafoordska Stiftelsen

2018/01 - 2020/12

Generating Dendritic Cells by Direct Reprogramming

CAN 2017/745

Principal investigator

Lunds Universitet

Funders: Cancerfonden

2018/03/01 - 2020/02/29

AAC Grant for protecting intellectual property

04/SAICT/2017

Principal investigator

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

2018/06 - 2021/12/31

ReproDC: Generating Antigen Presenting Cells by Direct Reprogramming

CENTRO-01-0145-FEDER-030013

Principal investigator

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

2017/09 - 2024/12/31

Wallenberg Center for Molecular Medicine 4-year career package

WCMMLUPEREIRA

Principal investigator

Funders: Wallenberg Centre for Molecular Medicine

2017/01 - 2021/02/28

Consortium CANCEL_STEM: Tackling CANcer STEM CELls: a challenge and an opportunity to advance in anti-cancer therapy

CANCEL_STEM

Principal investigator

Funders: Fundação para a Ciência e a Tecnologia

2015/12/01 - 2018/12/01

Hemoinduction: mechanisms underlying hemogenic induction in human fibrobalsts

PTDC/BIM-MED/0075/2014

Principal investigator

Centro de Inovação em Biomedicina e Biotecnologia (CIBB)

Funders: Fundação para a Ciência e a Tecnologia

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