Catarina Cunha Santos

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Overview

Catarina Cunha Santos is a Technology Transfer Officer with more than 11 years of experience in drug discovery and development research. After receiving her PhD degree in Pharmaceutical Biotechnology from Lisbon University, CCS joined Prof Adrian Thrasher’s team in the prestigious GOS Institute of Child Health, University College London, a laboratory with expertise in clinical and translational research in gene and cell therapies. In 2019, she joined the Center for Neuroscience and Cell Biology to establish a Technology Transfer Office with a focus on the valorisation of biotechnological products applied to healthcare. Here, she is mainly responsible for assisting and advising researchers regarding Intellectual Property and commercial valorisation of the technologies developed at the institute. CCS is also responsible for educating and raising awareness in the areas of innovation and entrepreneurship. Recently, she started to do research on licensing of healthcare technologies from R&D Centres.

Publications

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Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.

Anti-HIV-1 Activity of pepRF1, a Proteolysis-Resistant CXCR4 Antagonist Derived from Dengue Virus Capsid Protein

Cadima-Couto, Iris; Tauzin, Alexandra; Freire, João M.; Figueira, Tiago N.; Silva, Rúben D. M.; Pérez-Peinado, Clara; Cunha-Santos, C; et al, ACS Infect Dis.. 6 - 22. 1. 7. 2021. https://pubmed.ncbi.nlm.nih.gov/33319557/ . published ACS Infect Dis.

Protein Delivery of Cell-Penetrating Zinc-Finger Activators Stimulates Latent HIV-1-Infected Cells

Perdigão, Pedro R.L.; Cunha-Santos, Catarina; Barbas, Carlos F.; Santa-Marta, Mariana; Goncalves, Joao, Molecular Therapy - Methods & Clinical Development. 145 - 158. 18. 2020. http://dx.doi.org/10.1016/j.omtm.2020.05.016 . 10.1016/j.omtm.2020.05.016 . published Molecular Therapy - Methods & Clinical Development

Inhibition of HIV replication through siRNA carried by CXCR4-targeted chimeric nanobody

Cunha-Santos, Catarina; Perdigão, PRL; Martin, Francisco; Oliveira, Joana Gomes; Cardoso, Miguel; Manuel, Ana; Taveira, Nuno; Goncalves, Joao, Cellular and Molecular Life Sciences. 2019. http://dx.doi.org/10.1007/s00018-019-03334-8 . 10.1007/s00018-019-03334-8 . published Cellular and Molecular Life Sciences

Antigenic response to CT-P13 and infliximab originator in inflammatory bowel disease patients shows similar epitope recognition

Goncalves, J.; Santos, M.; Acurcio, R.; Iria, I.; Gouveia, L.; Matos Brito, P.; Catarina Cunha-Santos, A.; et al, Alimentary Pharmacology & Therapeutics. 507 - 522. 5. 48. 2018. http://dx.doi.org/10.1111/apt.14808 . 10.1111/apt.14808 . Alimentary Pharmacology & Therapeutics

Characterization of plasma labile heme in hemolytic conditions

Gouveia, Zélia; Carlos, Ana R.; Yuan, Xiaojing; Aires-da-Silva, Frederico; Stocker, Roland; Maghzal, Ghassan J.; Leal, Sónia S.; et al, The FEBS Journal. 3278 - 3301. 19. 284. 2017. http://dx.doi.org/10.1111/febs.14192 . 10.1111/febs.14192 . published The FEBS Journal

Albumin-binding domain from Streptococcus zooepidemicus protein Zag as a novel strategy to improve the half-life of therapeutic proteins

Cantante, Cátia; Lourenço, Sara; Morais, Maurício; Leandro, João; Gano, Lurdes; Silva, Nuno; Leandro, Paula; et al, Journal of Biotechnology. 23 - 33. 253. 2017. http://dx.doi.org/10.1016/j.jbiotec.2017.05.017 . 10.1016/j.jbiotec.2017.05.017 . Journal of Biotechnology

Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance

Figueira, Tiago N.; Freire, João M.; Cunha-Santos, Catarina; Heras, Montserrat; Gonçalves, João; Moscona, Anne; Porotto, Matteo; Salomé Veiga, Ana; Castanho, Miguel A. R. B., Scientific Reports. 1. 7. 2017. http://dx.doi.org/10.1038/srep45647 . 10.1038/srep45647 . Scientific Reports

Development of synthetic light-chain antibodies as novel and potent HIV fusion inhibitors

Cunha-Santos, Catarina; Figueira, Tiago N.; Borrego, Pedro; Oliveira, Soraia S.; Rocha, Cheila; Couto, Andreia; Cantante, Cátia; et al, AIDS. 1691 - 1701. 11. 30. 2016. http://dx.doi.org/10.1097/qad.0000000000001108 . 10.1097/qad.0000000000001108 . AIDS

Biodistribution of a 67Ga-labeled anti-TNF VHH single-domain antibody containing a bacterial albumin-binding domain (Zag)

Morais, Maurício; Cantante, Cátia; Gano, Lurdes; Santos, Isabel; Lourenço, Sara; Santos, Catarina; Fontes, Carlos; et al, Nuclear Medicine and Biology. e44 - e48. 41. 2014. http://dx.doi.org/10.1016/j.nucmedbio.2014.01.009 . 10.1016/j.nucmedbio.2014.01.009 . Nuclear Medicine and Biology

Is prnt a Pseudogene? Identification of Ram Prt in Testis and Ejaculated Spermatozoa

Pimenta, Jorge; Domingos, Ana; Santos, Pedro; Marques, Carla C.; Cantante, Cátia; Santos, Ana; Barbas, João P.; et al, PLoS ONE. 8. 7. 2012. http://dx.doi.org/10.1371/journal.pone.0042957 . 10.1371/journal.pone.0042957 . PLoS ONE

Assessing combinatorial strategies to multimerize libraries of single-domain antibodies

Oliveira, Soraia S.; Aires da Silva, Frederico; Lourenco, Sara; Freitas-Vieira, Acilino; Cunha Santos, Ana Catarina; Goncalves, Joao, Biotechnology and Applied Biochemistry. 193 - 204. 3. 59. 2012. http://dx.doi.org/10.1002/bab.1011 . 10.1002/bab.1011 . Biotechnology and Applied Biochemistry

HIV-1 Vif Interaction with APOBEC3 Deaminases and its Characterization by a New Sensitive Assay

Cadima-Couto, Iris; Saraiva, Nuno; Santos, Ana Catarina C.; Goncalves, Joao, Journal of Neuroimmune Pharmacology. 296 - 307. 2. 6. 2011. http://dx.doi.org/10.1007/s11481-011-9258-7 . 10.1007/s11481-011-9258-7 . Journal of Neuroimmune Pharmacology

All projects

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Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.

2020/04 - 2020/12

BrainHealth 2020 – Detecção Precoce, Neuro-Modulação e Terapias Avançadas para Neuropatologias

CENTRO-01-0145-FEDER-000008

Post-doc Fellow

Universidade de Coimbra

Funders: Comissão de Coordenação e Desenvolvimento Regional do Centro

2019/07 - 2020/03

LifeSciences ByCENTRO: Valorização do Conhecimento em Ciências da Vida

CENTRO-01-0246-FEDER-000011

Other

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Comissão de Coordenação e Desenvolvimento Regional do Centro

2019/04 - 2020/03

Gene editing for X-linked agammaglobulinemia

Not Applicable

Other

University College London Great Ormond Street Institute of Child Health

Funders: NIHR Great Ormond Street Hospital Biomedical Research Centre

2019/04 - 2020/03

Gene editing for X-linked agammaglobulinemia

Not Applicable

Other

University College London Great Ormond Street Institute of Child Health

Funders: NIHR Great Ormond Street Hospital Biomedical Research Centre

2016/01 - 2016/12

Multidisciplinary Strategy to Develop Novel Multicomponent Nanoscale Systems for Immune Modulation

info:eu-repo/grantAgreement/FCT/3599-PPCDT/137413/PT

Research Fellow

Farm-ID Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento

Funders: Fundação para a Ciência e a Tecnologia

2014/03 - 2016/02

An innovative approach to deliver dual-targeting HIV entry inhibitors using cationic liposomes

info:eu-repo/grantAgreement/FCT/3599-PPCDT/135844/PT

Researcher

Funders: Fundação para a Ciência e a Tecnologia

2012/01 - 2014/12

ArmAb: New strategy of ADC for arming antibodies in cancer therapy

info:eu-repo/grantAgreement/FCT/3599-PPCDT/119173/PT

Researcher

Universidade de Lisboa - Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia

Funders: Fundação para a Ciência e a Tecnologia

2011/09 - 2015/08

ENGINEERING SYNTHETIC DOMAIN ANTIBODIES WITH BROAD AND POTENT HIV-1 NEUTRALIZATION

info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F738382%F2010/PT

PhD Student Fellow

Universidade de Lisboa Instituto de Investigação do Medicamento

Funders: Fundação para a Ciência e a Tecnologia

2011/03 - 2011/08

Albumin binding-domain fusions to improve protein pharmacokinetics

info:eu-repo/grantAgreement/FCT/3599-PPCDT/115846/PT

Research Fellow

Universidade de Lisboa - Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia

Funders: Fundação para a Ciência e a Tecnologia

2009/05 - 2011/02

A Novel Lentiviral Target-Specific Strategy for Molecular and Gene Therapy

PTDC/BIA-BCM/64275/2006

Research Fellow

Universidade de Lisboa - Associação para o Desenvolvimento do Ensino e Investigação da Microbiologia

Funders: Fundação para a Ciência e a Tecnologia

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