Inês Esteves Baldeiras

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Information about journal articles, updated at 26-06-2022, from platform CIÊNCIAVITAE.

Diagnostic accuracy of cerebrospinal fluid biomarkers in genetic prion diseases

Schmitz, Matthias; Villar-Piqué, Anna; Hermann, Peter; Escaramís, Geòrgia; Calero, Miguel; Chen, Cao; Kruse, Niels; et al, Brain. 700 - 712. 2. 145. 2022. http://dx.doi.org/10.1093/brain/awab350 . 10.1093/brain/awab350 . Brain

Lewy body dementia is associated with an increased risk of atrial fibrillation: A case-control study

Tábuas-Pereira, Miguel; Durães, João; Beato-Coelho, José; Rita Nogueira, Ana; Duro, Diana; Baldeiras, Inês; Santana, Isabel, Journal of Clinical Neuroscience. 62 - 65. 99. 2022. http://dx.doi.org/10.1016/j.jocn.2022.02.038 . 10.1016/j.jocn.2022.02.038 . Journal of Clinical Neuroscience

Posttranslational modifications of proteins are key features in the identification of CSF biomarkers of multiple sclerosis

Salazar, Ivan L.; Lourenço, Ana S. T.; Manadas, Bruno; Baldeiras, Inês; Ferreira, Cláudia; Teixeira, Anabela Claro; Mendes, Vera M.; et al, Journal of Neuroinflammation. 1. 19. 2022. http://dx.doi.org/10.1186/s12974-022-02404-2 . 10.1186/s12974-022-02404-2 . Journal of Neuroinflammation

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Jansen, Willemijn J.; Janssen, Olin; Tijms, Betty M.; Vos, Stephanie J. B.; Ossenkoppele, Rik; Visser, Pieter Jelle; Aarsland, Dag; et al, JAMA Neurology. 3. 79. 2022. http://dx.doi.org/10.1001/jamaneurol.2021.5216 . 10.1001/jamaneurol.2021.5216 . JAMA Neurology

Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress-induced cell damage

Free Radical Biology and Medicine. 119 - 132. 179. 2022. http://dx.doi.org/10.1016/j.freeradbiomed.2021.12.304 . 10.1016/j.freeradbiomed.2021.12.304 . Free Radical Biology and Medicine

The Road to Personalized Medicine in Alzheimer’s Disease: The Use of Artificial Intelligence

Anuschka Silva-Spínola; Inês Baldeiras; Joel P. Arrais; Isabel Santana, Biomedicines. 315 - 315. 2. 10. 2022. https://doi.org/10.3390/biomedicines10020315 . 10.3390/biomedicines10020315 . Biomedicines

Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers

Alzheimer's Research & Therapy. 1. 14. 2022. http://dx.doi.org/10.1186/s13195-021-00955-9 . 10.1186/s13195-021-00955-9 . Alzheimer's Research & Therapy

Neuropsychological features of progranulin-associated frontotemporal dementia: A nested case-control study

Lima, M.; Tábuas-Pereira, M.; Duro, D.; Durães, J.; Vieira, D.; Baldeiras, I.; Almeida, M.; Santana, I., Neural Regeneration Research. 910 - 915. 5. 16. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097076140&partnerID=MN8TOARS . 10.4103/1673-5374.297082 . Neural Regeneration Research

DNA Methylation Is Correlated with Oxidative Stress in Myelodysplastic Syndrome—Relevance as Complementary Prognostic Biomarkers

Ana Cristina Gonçalves; Raquel Alves; Inês Baldeiras; Bárbara Marques; Bárbara Oliveiros; Amélia Pereira; José Manuel Nascimento Costa; et al, Cancers. 3138 - 3138. 13. 13. 2021. https://doi.org/10.3390/cancers13133138 . 10.3390/cancers13133138 . Cancers

Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction

Susana P. Pereira; Ludgero C. Tavares; Ana I. Duarte; Inês Baldeiras; Teresa Cunha-Oliveira; João D. Martins; Maria S. Santos; et al, Clinical Science. 2021. https://doi.org/10.1042/CS20201339 . 10.1042/CS20201339 . Clinical Science

Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial Frontotemporal dementia

Silva-Spínola, Anuschka; Lima, Marisa; Leitão, Maria João; Durães, João; Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Santana, Isabel; Baldeiras, Inês, European Journal of Neurology. 2021. http://dx.doi.org/10.1111/ene.15058 . 10.1111/ene.15058 . European Journal of Neurology

Vasculitic peripheral neuropathy in deficiency of adenosine deaminase 2

Carneiro, Diogo Reis; Rebelo, Olinda; Matos, Anabela; Baldeiras, Inês; Almendra, Luciano; Fernandes, Carolina; Negrão, Luís; et al, Neuromuscular Disorders. 2021. http://dx.doi.org/10.1016/j.nmd.2021.05.001 . 10.1016/j.nmd.2021.05.001 . Neuromuscular Disorders

Oxidative Stress Parameters Can Predict the Response to Erythropoiesis-Stimulating Agents in Myelodysplastic Syndrome Patients

Gonçalves, Ana Cristina; Alves, Raquel; Baldeiras, Inês; Jorge, Joana; Marques, Bárbara; Paiva, Artur; Oliveiros, Bárbara; et al, Frontiers in Cell and Developmental Biology. 9. 2021. http://dx.doi.org/10.3389/fcell.2021.701328 . 10.3389/fcell.2021.701328 . Frontiers in Cell and Developmental Biology

Estimates of Geriatric Delirium Frequency in Noncardiac Surgeries and Its Evaluation Across the Years: A Systematic Review and Meta-Analysis

Silva, Ana Rita; Regueira, Patrícia; Albuquerque, Elisabete; Baldeiras, Inês; Cardoso, Ana Luísa; Santana, Isabel; Cerejeira, Joaquim; et al, Journal of the American Medical Directors Association. 613 - 620.e9. 3. 22. 2021. http://dx.doi.org/10.1016/j.jamda.2020.08.017 . 10.1016/j.jamda.2020.08.017 . Journal of the American Medical Directors Association

Cognitive Trajectories Following Acute Infection in Older Patients With and Without Cognitive Impairment: An 1-Year Follow-Up Study

Frontiers in Psychiatry. 12. 2021. http://dx.doi.org/10.3389/fpsyt.2021.754489 . 10.3389/fpsyt.2021.754489 . Frontiers in Psychiatry

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

Llorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel; et al, Nature Communications. 1. 11. 2020. http://dx.doi.org/10.1038/s41467-020-14373-2 . 10.1038/s41467-020-14373-2 . Nature Communications

Neuropsychological Contribution to Predict Conversion to Dementia in Patients with Mild Cognitive Impairment Due to Alzheimer’s Disease

Silva, Dina; Cardoso, Sandra; Guerreiro, Manuela; Maroco, João; Mendes, Tiago; Alves, Luísa; Nogueira, Joana; et al, Journal of Alzheimer's Disease. 1 - 12. 2020. http://dx.doi.org/10.3233/jad-191133 . 10.3233/jad-191133 . Journal of Alzheimer's Disease

A different vision of translational research in biomarker discovery: a pilot study on circulatory mitochondrial proteins as Parkinson’s disease potential biomarkers

Anjo, Sandra I.; dos Santos, Patrícia Valério; Rosado, Luiza; Baltazar, Graça; Baldeiras, Inês; Pires, Diana; Gomes, Andreia; et al, Translational Neurodegeneration. 1. 9. 2020. http://dx.doi.org/10.1186/s40035-020-00188-0 . 10.1186/s40035-020-00188-0 . Translational Neurodegeneration

Neuropsychological profile of amyloid-positive versus amyloid-negative amnestic Mild Cognitive Impairment

Alves, L.; Cardoso, S.; Silva, D.; Mendes, T.; Marôco, J.; Nogueira, J.; Lima, M.; et al, Journal of Neuropsychology. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85087142245&partnerID=MN8TOARS . 10.1111/jnp.12218 . Journal of Neuropsychology

C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia

Fernandes, A.; Tábuas-Pereira, M.; Duro, D.; Lima, M.; Gens, H.; Santiago, B.; Durães, J.; et al, Experimental Gerontology. 138. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85086792594&partnerID=MN8TOARS . 10.1016/j.exger.2020.111004 . Experimental Gerontology

Increased c-x-c motif chemokine ligand 12 levels in cerebrospinal fluid as a candidate biomarker in sporadic amyotrophic lateral sclerosis

Andrés-Benito, P.; Povedano, M.; Domínguez, R.; Marco, C.; Colomina, M.J.; López-Pérez, Ó.; Santana, I.; et al, International Journal of Molecular Sciences. 1 - 21. 22. 21. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096189436&partnerID=MN8TOARS . 10.3390/ijms21228680 . International Journal of Molecular Sciences

A new tetra-plex fluorimetric assay for the quantification of cerebrospinal fluid ß-amyloid42, total-tau, phospho-tau and a-synuclein in the differential diagnosis of neurodegenerative dementia

Diaz-Lucena, Daniela; Escaramis, Geòrgia; Villar-Piqué, Anna; Hermann, Peter; Schmitz, Matthias; Varges, Daniela; Santana, Isabel; et al, Journal of Neurology. 2567 - 2581. 9. 267. 2020. http://dx.doi.org/10.1007/s00415-020-09870-9 . 10.1007/s00415-020-09870-9 . published Journal of Neurology

APOE ¿4-TOMM40L Haplotype Increases the Risk of Mild Cognitive Impairment Conversion to Alzheimer's Disease

Cardoso, R.; Lemos, C.; Oliveiros, B.; Almeida, M.R.; Baldeiras, I.; Pereira, C.F.; Santos, A.; et al, Journal of Alzheimer's Disease. 587 - 601. 2. 78. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85096134035&partnerID=MN8TOARS . 10.3233/JAD-200556 . Journal of Alzheimer's Disease

Patients with progranulin mutations overlap with the progressive dysexecutive syndrome: towards the definition of a frontoparietal dementia phenotype

Tábuas-Pereira, Miguel; Almeida, Maria Rosário; Duro, Diana; Lima, Marisa; Durães, João; Guerreiro, Rita; Brás, José; Baldeiras, Inês; Santana, Isabel, Brain Communications. 2. 2. 2020. http://dx.doi.org/10.1093/braincomms/fcaa126 . 10.1093/braincomms/fcaa126 . published Brain Communications

Increased CSF tau is associated with a higher risk of seizures in patients with Alzheimer's disease

Tábuas-Pereira, Miguel; Durães, João; Lopes, Joana; Sales, Francisco; Bento, Conceição; Duro, Diana; Santiago, Beatriz; et al, Epilepsy & Behavior. 207 - 209. 98. 2019. http://dx.doi.org/10.1016/j.yebeh.2019.06.033 . 10.1016/j.yebeh.2019.06.033 . Epilepsy & Behavior

Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer’s disease

Baldeiras, Inês; Santana, Isabel; Leitão, Maria João; Vieira, Daniela; Duro, Diana; Mroczko, Barbara; Kornhuber, Johannes; Lewczuk, Piotr, Alzheimer's Research & Therapy. 1. 11. 2019. http://dx.doi.org/10.1186/s13195-018-0456-x . 10.1186/s13195-018-0456-x . Alzheimer's Research & Therapy

Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease Patients

Zerr, Inga; Villar-Piqué, Anna; Schmitz, Vanda Edit; Poleggi, Anna; Pocchiari, Maurizio; Sánchez-Valle, Raquel; Calero, Miguel; et al, Biomolecules. 12. 9. 2019. http://dx.doi.org/10.3390/biom9120800 . 10.3390/biom9120800 . Biomolecules

Lower CSF Amyloid-Beta1–42 Predicts a Higher Mortality Rate in Frontotemporal Dementia

Vieira, Daniela; Durães, João; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Lima, Marisa; Leitão, Maria João; Tábuas-Pereira, Miguel; Santana, Isabel, Diagnostics. 4. 9. 2019. http://dx.doi.org/10.3390/diagnostics9040162 . 10.3390/diagnostics9040162 . Diagnostics

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

van Maurik, I.S.; Vos, S.J.; Bos, I.; Bouwman, F.H.; Teunissen, C.E.; Scheltens, P.; Barkhof, F.; et al, The Lancet Neurology. 1034 - 1044. 11. 18. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072867961&partnerID=MN8TOARS . 10.1016/S1474-4422(19)30283-2 . The Lancet Neurology

PBMCs as a potential source of biomarkers in neurodegenerative diseases – preliminary study

Anjo, Sandra; Silva, Rafael; Baldeiras, Ines; Mendonça, Alexandre; Januário, Cristina; Santana, Isabel; Verdelho, Ana; et al, Frontiers in Cellular Neuroscience. 13. 2019. http://dx.doi.org/10.3389/conf.fncel.2019.01.00001 . 10.3389/conf.fncel.2019.01.00001 . published Frontiers in Cellular Neuroscience

Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer’s disease

Maria João Leitão; Anuschka Silva-Spínola; Isabel Santana; Veronica Olmedo; Alicia Nadal; Nathalie Le Bastard; Inês Baldeiras, Alzheimer's Research & Therapy. 2019. https://doi.org/10.1186/s13195-019-0550-8 . 10.1186/s13195-019-0550-8 . Alzheimer's Research & Therapy

CSF IgG oligoclonal bands and prognosis in multiple sclerosis

Valado, A; Sousa, L; Baldeiras, I, European Journal of Public Health. Supplement. 29. 2019. http://dx.doi.org/10.1093/eurpub/ckz034.016 . 10.1093/eurpub/ckz034.016 . European Journal of Public Health

Association between adipokines and biomarkers of Alzheimer's disease: A cross-sectional study

Letra, L.; Matafome, P.; Rodrigues, T.; Duro, D.; Lemos, R.; Baldeiras, I.; Patrcio, M.; et al, Journal of Alzheimer's Disease. 725 - 735. 2. 67. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060571460&partnerID=MN8TOARS . 10.3233/JAD-180669 . Journal of Alzheimer's Disease

CEREBROSPINAL FLUID Aß42 AND TAU MEASUREMENT ON LUMIPULSE® G: ANALYTICAL VERIFICATION AND METHOD COMPARISON

Leitão, Maria João; Santana, Isabel; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês, Alzheimer's & Dementia. 7. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2018.06.286 . 10.1016/j.jalz.2018.06.286 . Alzheimer's & Dementia

Association of Cerebral Amyloid-ß Aggregation With Cognitive Functioning in Persons Without Dementia

Jansen, Willemijn J.; Ossenkoppele, Rik; Tijms, Betty M.; Fagan, Anne M.; Hansson, Oskar; Klunk, William E.; van der Flier, Wiesje M.; et al, JAMA Psychiatry. 1. 75. 2018. http://dx.doi.org/10.1001/jamapsychiatry.2017.3391 . 10.1001/jamapsychiatry.2017.3391 . JAMA Psychiatry

Cerebrospinal fluid neurofilament light levels in neurodegenerative dementia: Evaluation of diagnostic accuracy in the differential diagnosis of prion diseases

Zerr, Inga; Schmitz, Matthias; Karch, André; Villar-Piqué, Anna; Kanata, Eirini; Golanska, Ewa; Díaz-Lucena, Daniela; et al, Alzheimer's & Dementia. 751 - 763. 6. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2017.12.008 . 10.1016/j.jalz.2017.12.008 . Alzheimer's & Dementia

Underlying Biological Processes in Mild Cognitive Impairment: Amyloidosis Versus Neurodegeneration

Santana, Isabel; Baldeiras, Inês; Santiago, Beatriz; Duro, Diana; Freitas, Sandra; Pereira, Miguel Tábuas; Almeida, Maria Rosário; et al, Journal of Alzheimer's Disease. S647 - S657. s1. 64. 2018. http://dx.doi.org/10.3233/jad-179908 . 10.3233/jad-179908 . Journal of Alzheimer's Disease

Prevalence of the apolipoprotein E e4 allele in amyloid ß positive subjects across the spectrum of Alzheimer's disease

Mattsson, Niklas; Groot, Colin; Jansen, Willemijn J.; Landau, Susan M.; Villemagne, Victor L.; Engelborghs, Sebastiaan; Mintun, Mark M.; et al, Alzheimer's & Dementia. 913 - 924. 7. 14. 2018. http://dx.doi.org/10.1016/j.jalz.2018.02.009 . 10.1016/j.jalz.2018.02.009 . Alzheimer's & Dementia

The Head Turning Sign in Dementia and Mild Cognitive Impairment: Its Relationship to Cognition, Behavior, and Cerebrospinal Fluid Biomarkers

Durães, João; Tábuas-Pereira, Miguel; Araújo, Rui; Duro, Diana; Baldeiras, Inês; Santiago, Beatriz; Santana, Isabel, Dementia and Geriatric Cognitive Disorders. 42 - 49. 1-2. 46. 2018. http://dx.doi.org/10.1159/000486531 . 10.1159/000486531 . Dementia and Geriatric Cognitive Disorders

Addition of the Aß42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer’s disease dementia in mild cognitive impairment

Inês Baldeiras; Isabel Santana; Maria João Leitão; Helena Gens; Rui Pascoal; Miguel Tábuas-Pereira; José Beato-Coelho; et al, Alzheimer's Research & Therapy. 1. 10. 2018. https://doi.org/10.1186/s13195-018-0362-2 . 10.1186/s13195-018-0362-2 . Alzheimer's Research & Therapy

Cerebrospinal Fluid Total Prion Protein in the Spectrum of Prion Diseases

Villar-Piqué, Anna; Schmitz, Matthias; Lachmann, Ingolf; Karch, André; Calero, Olga; Stehmann, Christiane; Sarros, Shannon; et al, Molecular Neurobiology. 2811 - 2821. 4. 56. 2018. http://dx.doi.org/10.1007/s12035-018-1251-1 . 10.1007/s12035-018-1251-1 . Molecular Neurobiology

Quantitative genetics validates previous genetic variants and identifies novel genetic players influencing Alzheimer's disease cerebrospinal fluid biomarkers

Ramos De Matos, M.; Ferreira, C.; Herukka, S.-K.; Soininen, H.; Janeiro, A.; Santana, I.; Baldeiras, I.; et al, Journal of Alzheimer's Disease. 639 - 652. 2. 66. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055989436&partnerID=MN8TOARS . 10.3233/JAD-180512 . Journal of Alzheimer's Disease

Adenosine Deaminase Two and Immunoglobulin M Accurately Differentiate Adult Sneddon’s Syndrome of Unknown Cause

Santo, Gustavo C.; Baldeiras, Inês; Guerreiro, Rita; Ribeiro, Joana A.; Cunha, Rosário; Youngstein, Taryn; Nanthapisal, Sira; et al, Cerebrovascular Diseases. 257 - 264. 5-6. 46. 2018. http://dx.doi.org/10.1159/000495794 . 10.1159/000495794 . Cerebrovascular Diseases

Influence of butyrylcholinesterase in progression of mild cognitive impairment to Alzheimer's disease

Gabriel, A.J.; Almeida, M.R.; Ribeiro, M.H.; Carneiro, D.; Valério, D.; Pinheiro, A.C.; Pascoal, R.; et al, Journal of Alzheimer's Disease. 1097 - 1105. 3. 61. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85048206568&partnerID=MN8TOARS . 10.3233/JAD-170695 . Journal of Alzheimer's Disease

Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer’s Disease Cerebrospinal Fluid Biomarkers

Ramos de Matos, Mafalda; Ferreira, Catarina; Herukka, Sanna-Kaisa; Soininen, Hilkka; Janeiro, André; Santana, Isabel; Baldeiras, Inês; et al, Journal of Alzheimer's Disease. 639 - 652. 2. 66. 2018. http://dx.doi.org/10.3233/jad-180512 . 10.3233/jad-180512 . Journal of Alzheimer's Disease

Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment

Herukka, S.-K.; Simonsen, A.H.; Andreasen, N.; Baldeiras, I.; Bjerke, M.; Blennow, K.; Engelborghs, S.; et al, Alzheimer's and Dementia. 285 - 295. 3. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007323510&partnerID=MN8TOARS . 10.1016/j.jalz.2016.09.009 . Alzheimer's and Dementia

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

Van Waalwijk Van Doorn, L.J.C.; Gispert, J.D.; Kuiperij, H.B.; Claassen, J.A.H.R.; Arighi, A.; Baldeiras, I.; Blennow, K.; et al, Journal of Alzheimer's Disease. 543 - 555. 2. 56. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011320275&partnerID=MN8TOARS . 10.3233/JAD-160668 . Journal of Alzheimer's Disease

Development of a mitochondriotropic antioxidant based on caffeic acid: Proof of concept on cellular and mitochondrial oxidative stress models

Teixeira, J.; Cagide, F.; Benfeito, S.; Soares, P.; Garrido, J.; Baldeiras, I.; Ribeiro, J.A.; et al, Journal of Medicinal Chemistry. 7084 - 7098. 16. 60. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85028330575&partnerID=MN8TOARS . 10.1021/acs.jmedchem.7b00741 . Journal of Medicinal Chemistry

Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia

Simonsen, A.H.; Herukka, S.-K.; Andreasen, N.; Baldeiras, I.; Bjerke, M.; Blennow, K.; Engelborghs, S.; et al, Alzheimer's and Dementia. 274 - 284. 3. 13. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85007289521&partnerID=MN8TOARS . 10.1016/j.jalz.2016.09.008 . Alzheimer's and Dementia

Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with risk and clinical course the disease

Valado, A.; Leitão, M.J.; Martinho, A.; Pascoal, R.; Cerqueira, J.; Correia, I.; Batista, S.; Sousa, L.; Baldeiras, I., Multiple Sclerosis and Related Disorders. 71 - 76. 11. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006760578&partnerID=MN8TOARS . 10.1016/j.msard.2016.12.003 . Multiple Sclerosis and Related Disorders

Phytoestrogen coumestrol improves mitochondrial activity and decreases oxidative stress in the brain of ovariectomized Wistar-Han rats

Moreira, A.C.; Silva, A.M.; Branco, A.F.; Baldeiras, I.; Pereira, G.C.; Seiça, R.; Santos, M.S.; Sardão, V.A., Journal of Functional Foods. 329 - 339. 34. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019053766&partnerID=MN8TOARS . 10.1016/j.jff.2017.05.002 . Journal of Functional Foods

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

Bos, I.; Vos, S.J.; Frölich, L.; Kornhuber, J.; Wiltfang, J.; Maier, W.; Peters, O.; et al, Neurobiology of Aging. 33 - 40. 56. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018725939&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2017.03.034 . Neurobiology of Aging

Genetic variants involved in oxidative stress, base excision repair, DNA methylation, and folate metabolism pathways influence myeloid neoplasias susceptibility and prognosis

Gonçalves, A.C.; Alves, R.; Baldeiras, I.; Cortesão, E.; Carda, J.P.; Branco, C.C.; Oliveiros, B.; et al, Molecular Carcinogenesis. 130 - 148. 1. 56. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960156457&partnerID=MN8TOARS . 10.1002/mc.22478 . Molecular Carcinogenesis

Association between butyrylcholinesterase and cerebrospinal fluid biomarkers in Alzheimer's disease patients

Gabriel, A.J.; Almeida, M.R.; Ribeiro, M.H.; Durães, J.; Tábuas-Pereira, M.; Pinheiro, A.C.; Pascoal, R.; Santana, I.; Baldeiras, I., Neuroscience Letters. 101 - 106. 641. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85012253710&partnerID=MN8TOARS . 10.1016/j.neulet.2017.01.036 . Neuroscience Letters

Prognosis of Early-Onset <em>vs.</em> Late-Onset Mild Cognitive Impairment: Comparison of Conversion Rates and Its Predictors

Baldeiras, Ines, Geriatrics. 2016. http://www.mdpi.com/2308-3417/1/2/11 . 10.3390/geriatrics1020011 . Geriatrics

Corticobasal syndrome in a dementia outpatient clinic: From clinical phenomenology to etiological diagnosis | Síndrome corticobasal numa consulta de demências: Da fenomenologia clínica ao diagnóstico etiológico

Arenga, M.; Pereira, M.; Santiago, B.; Baldeiras, I.; Almeida, M.R.; Santana, I., Sinapse. 18 - 26. 1. 16. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026801394&partnerID=MN8TOARS . Sinapse

Sporadic Creutzfeldt-Jakob disease diagnostic accuracy is improved by a new CSF ELISA 14-3-3¿ assay

Leitão, M.J.; Baldeiras, I.; Almeida, M.R.; Ribeiro, M.H.; Santos, A.C.; Ribeiro, M.; Tomás, J.; et al, Neuroscience. 398 - 407. 322. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960172114&partnerID=MN8TOARS . 10.1016/j.neuroscience.2016.02.057 . Neuroscience

Validation of 14-3-3 Protein as a Marker in Sporadic Creutzfeldt-Jakob Disease Diagnostic

Schmitz, M.; Ebert, E.; Stoeck, K.; Karch, A.; Collins, S.; Calero, M.; Sklaviadis, T.; et al, Molecular Neurobiology. 2189 - 2199. 4. 53. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928958024&partnerID=MN8TOARS . 10.1007/s12035-015-9167-5 . Molecular Neurobiology

CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt–Jakob disease suspected cases with inconclusive 14-3-3 result

Leitão, M.J.; Baldeiras, I.; Almeida, M.R.; Ribeiro, M.H.; Santos, A.C.; Ribeiro, M.; Tomás, J.; et al, Journal of Neurology. 1847 - 1861. 9. 263. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976407297&partnerID=MN8TOARS . 10.1007/s00415-016-8209-x . Journal of Neurology

Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation

Almeida, M.R.; Macário, M.C.; Ramos, L.; Baldeiras, I.; Ribeiro, M.H.; Santana, I., Neurobiology of Aging. 200.e1 - 200.e5. 41. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84963540872&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2016.02.019 . Neurobiology of Aging

Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics

Lelental, N.; Brandner, S.; Kofanova, O.; Blennow, K.; Zetterberg, H.; Andreasson, U.; Engelborghs, S.; et al, Journal of Alzheimer's Disease. 51 - 64. 1. 52. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973131635&partnerID=MN8TOARS . 10.3233/JAD-150883 . Journal of Alzheimer's Disease

The central biobank and virtual biobank of BIOMARKAPD: A resource for studies on neurodegenerative diseases

Reijs, B.L.R.; Teunissen, C.E.; Goncharenko, N.; Betsou, F.; Blennow, K.; Baldeiras, I.; Brosseron, F.; et al, Frontiers in Neurology. OCT. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946561925&partnerID=MN8TOARS . 10.3389/fneur.2015.00216 . Frontiers in Neurology

Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-ß Levels in Patients with Alzheimer's Disease?

Travassos, M.; Santana, I.; Baldeiras, I.; Tsolaki, M.; Gkatzima, O.; Genc, S.; Yener, G.G.; et al, Journal of Alzheimer's Disease. 1069 - 1078. 4. 47. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939450783&partnerID=MN8TOARS . 10.3233/JAD-150374 . Journal of Alzheimer's Disease

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

Kruse, N.; Persson, S.; Alcolea, D.; Bahl, J.M.C.; Baldeiras, I.; Capello, E.; Chiasserini, D.; et al, Neurobiology of Aging. 2587 - 2596. 9. 36. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940467315&partnerID=MN8TOARS . 10.1016/j.neurobiolaging.2015.05.003 . Neurobiology of Aging

Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells

Loureiro, R.; Magalhães-Novais, S.; Mesquita, K.A.; Baldeiras, I.; Sousa, I.S.; Tavares, L.C.; Barbosa, I.A.; Oliveira, P.J.; Vega-Naredo, I., Oncotarget. 17081 - 17096. 19. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938269913&partnerID=MN8TOARS . Oncotarget

Prevalence of cerebral amyloid pathology in persons without dementia: A meta-analysis

Jansen, W.J.; Ossenkoppele, R.; Knol, D.L.; Tijms, B.M.; Scheltens, P.; Verhey, F.R.J.; Visser, P.J.; et al, JAMA - Journal of the American Medical Association. 1924 - 1938. 19. 313. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937529452&partnerID=MN8TOARS . 10.1001/jama.2015.4668 . JAMA - Journal of the American Medical Association

Cerebrospinal fluid Aß40 is similarly reduced in patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease

Inês Baldeiras; Isabel Santana; Maria João Leitão; Maria Helena Ribeiro; Rui Pascoal; Diana Duro; Raquel Lemos; et al, Journal of the Neurological Sciences. 308 - 316. 1-2. 358. 2015. http://dx.doi.org/10.1016/j.jns.2015.09.022 . 10.1016/j.jns.2015.09.022 . Journal of the Neurological Sciences

Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease

Mota, S.I.; Costa, R.O.; Ferreira, I.L.; Santana, I.; Caldeira, G.L.; Padovano, C.; Fonseca, A.C.; et al, Biochimica et Biophysica Acta - Molecular Basis of Disease. 1428 - 1441. 7. 1852. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928128412&partnerID=MN8TOARS . 10.1016/j.bbadis.2015.03.015 . Biochimica et Biophysica Acta - Molecular Basis of Disease

Chasing the effects of pre-analytical confounders - A multicenter study on CSF-AD biomarkers

Leitão, M.J.; Baldeiras, I.; Herukka, S.-K.; Pikkarainen, M.; Leinonen, V.; Simonsen, A.H.; Perret-Liaudet, A.; et al, Frontiers in Neurology. JUL. 6. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940025040&partnerID=MN8TOARS . 10.3389/fneur.2015.00153 . Frontiers in Neurology

Progranulin peripheral levels as a screening tool for the identification of subjects with progranulin mutations in a portuguese cohort

Almeida, M.R.; Baldeiras, I.; Ribeiro, M.H.; Santiago, B.; Machado, C.; Massano, J.; Guimarães, J.; et al, Neurodegenerative Diseases. 214 - 223. 4. 13. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893838273&partnerID=MN8TOARS . 10.1159/000352022 . Neurodegenerative Diseases

Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes

Carvalho, C.; Correia, S.C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I., Current Neurovascular Research. 330 - 339. 4. 11. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84925786114&partnerID=MN8TOARS . Current Neurovascular Research

Rapeseed oil-rich di, et alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics

Monteiro, J.P.; Pereira, C.V.; Silva, A.M.; Maciel, E.; Baldeiras, I.; Peixoto, F.; Domingues, M.R.; Jurado, A.S.; Oliveira, P.J., Archives of Toxicology. 2151 - 2163. 12. 87. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84890550286&partnerID=MN8TOARS . 10.1007/s00204-013-1068-7 . Archives of Toxicology

Prodromal metabolic phenotype in MCI cybrids: Implications for Alzheimer's disease

Silva, D.F.; Santana, I.; Esteves, A.R.; Baldeiras, I.; Arduino, D.M.; Oliveira, C.R.; Cardoso, S.M., Current Alzheimer Research. 180 - 190. 2. 10. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875000768&partnerID=MN8TOARS . 10.2174/1567205011310020008 . Current Alzheimer Research

Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance

Cardoso, S.; Santos, R.X.; Correia, S.C.; Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I., Neurobiology of Disease. 1 - 12. 1. 49. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866491588&partnerID=MN8TOARS . 10.1016/j.nbd.2012.08.008 . Neurobiology of Disease

Transthyretin decrease in plasma of MCI and AD patients: Investigation of mechanisms for disease modulation

Ribeiro, C.A.; Santana, I.; Oliveira, C.; Baldeiras, I.; Moreira, J.; Saraiva, M.J.; Cardoso, I., Current Alzheimer Research. 881 - 889. 8. 9. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867714724&partnerID=MN8TOARS . 10.2174/156720512803251057 . Current Alzheimer Research

Differentiation-dependent doxorubicin toxicity on h9c2 cardiomyoblasts

Branco, A.F.; Sampaio, S.F.; Moreira, A.C.; Holy, J.; Wallace, K.B.; Baldeiras, I.; Oliveira, P.J.; Sardão, V.A., Cardiovascular Toxicology. 326 - 340. 4. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870546889&partnerID=MN8TOARS . 10.1007/s12012-012-9177-8 . Cardiovascular Toxicology

CSF biomarkers for the early diagnosis of Alzheimer's disease in a routine clinical setting - The first Portuguese study | Biomarcadores do LCR no diagnóstico precoce da doença de Alzheimer em ambiente clínico de rotina - o primeiro estudo em Portugal

Baldeiras, I.; Santana, I.; Garrucho, M.H.; Pascoal, R.; Lemos, R.; Santiago, B.; de Oliveira, C.R., Sinapse. 14 - 22. 2. 12. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872921979&partnerID=MN8TOARS . Sinapse

Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities

Carvalho, C.; Cardoso, S.; Correia, S.C.; Santos, R.X.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Moreira, P.I., Diabetes. 1234 - 1242. 5. 61. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860599622&partnerID=MN8TOARS . 10.2337/db11-1186 . Diabetes

Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase

Freitas, M.; Baldeiras, I.; Proença, T.; Alves, V.; Mota-Pinto, A.; Sarmento-Ribeiro, A., FEBS Open Bio. 119 - 128. 2. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862228730&partnerID=MN8TOARS . 10.1016/j.fob.2012.05.001 . FEBS Open Bio

Mitochondrial- and endoplasmic reticulum-associated oxidative stress in alzheimers disease: From pathogenesis to biomarkers

Ferreiro, E.; Baldeiras, I.; Ferreira, I.L.; Costa, R.O.; Rego, A.C.; Pereira, C.F.; Oliveira, C.R., International Journal of Cell Biology. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863688106&partnerID=MN8TOARS . 10.1155/2012/735206 . International Journal of Cell Biology

[Bilateral hyperintensity of the pulvinar and dorsomedial nucleus of the thalamus in sporadic Creutzfeldt-Jakob disease]. | Hiperintensidade bilateral do pulvinar e núcleo dorso-medial do tálamo na forma esporádica da doença de Creutzfeldt-Jakob.

Casimiro, C.; Martins, J.; Parreira, T.; Baldeiras, I.; Ribeiro, H.; Batista, S.; Machado, E.; et al, Acta médica portuguesa. 41 - 44. 25 Suppl 1. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891418124&partnerID=MN8TOARS . Acta médica portuguesa

Proteomics-Based technologies in the discovery of biomarkers for multiple sclerosis in the cerebrospinal fluid

Lourenço, A.S.T.; Baldeiras, I.; Grãos, M.; Duarte, C.B., Current Molecular Medicine. 326 - 349. 4. 11. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958096423&partnerID=MN8TOARS . Current Molecular Medicine

Memory decline and cerebrospinal fluid biomarkers in MCI

Baldeiras, Ines; Lemos, Raquel; Cunha, Catarina; Ribeiro, Maria Helena; Santiago, Beatriz; Oliveira, Catarina; Santana, Isabel, Alzheimer's & Dementia. 4. 7. 2011. http://dx.doi.org/10.1016/j.jalz.2011.05.909 . 10.1016/j.jalz.2011.05.909 . Alzheimer's & Dementia

Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes

Carvalho, C.; Santos, M.S.; Baldeiras, I.; Oliveira, C.R.; Seiça, R.; Moreira, P.I., Current Neurovascular Research. 288 - 300. 4. 7. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650657043&partnerID=MN8TOARS . Current Neurovascular Research

Sub-chronic administration of doxorubicin to Wistar rats results in oxidative stress and unaltered apoptotic signaling in the lung

Machado, N.G.; Baldeiras, I.; Pereira, G.C.; Pereira, S.P.; Oliveira, P.J., Chemico-Biological Interactions. 478 - 486. 3. 188. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78149466319&partnerID=MN8TOARS . 10.1016/j.cbi.2010.09.027 . Chemico-Biological Interactions

Oxidative damage and progression to Alzheimer's disease in patients with mild cognitive impairment

Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., Journal of Alzheimer's Disease. 1165 - 1177. 4. 21. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650467580&partnerID=MN8TOARS . 10.3233/JAD-2010-091723 . Journal of Alzheimer's Disease

Oxidative damage and mitochondrial dysfunction in patients with mild cognitive impairment and Alzheimer's disease

Baldeiras, Inês; Santana, Isabel; Proença, Maria Teresa; Garrucho, Maria Helena; Pascoal, Rui; Rodrigues, Ana; Duro, Diana; et al, Alzheimer's & Dementia. S503 - S504. 4. 6. 2010. http://dx.doi.org/10.1016/j.jalz.2010.05.1679 . 10.1016/j.jalz.2010.05.1679 . Alzheimer's & Dementia

Sporadic Creutzfeldt-Jakob disease causing a 2-years slowly progressive isolated dementia

MacHado, A.; Ribeiro, M.; Rodrigues, M.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; Santana, I.; et al, Behavioural Neurology. 175 - 179. 3-4. 21. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-72949094841&partnerID=MN8TOARS . 10.3233/BEN-2009-0238 . Behavioural Neurology

Diagnostic value of CSF protein profile in a Portuguese population of sCJD patients

Baldeiras, I.E.; Ribeiro, M.H.; Pacheco, P.; MacHado, Á.; Santana, I.; Cunha, L.; Oliveira, C.R., Journal of Neurology. 1540 - 1550. 9. 256. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-69549118450&partnerID=MN8TOARS . 10.1007/s00415-009-5160-0 . Journal of Neurology

Peripheral oxidative damage in mild cognitive impairment and mild Alzheimer's disease

Baldeiras, I.; Santana, I.; Proença, M.T.; Garrucho, M.H.; Pascoal, R.; Rodrigues, A.; Duro, D.; Oliveira, C.R., Journal of Alzheimer's Disease. 117 - 128. 1. 15. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-52449117220&partnerID=MN8TOARS . Journal of Alzheimer's Disease

Variant Creutzfeldt-Jacob disease: The second case in Portugal and in the same geographical region

Machado, Á.; Soares, H.; Antunes, H.; Magalhães, Z.; Ferreira, C.; Baldeiras, I.; Ribeiro, M.H.; et al, Journal of Neurology, Neurosurgery and Psychiatry. 180 - 182. 2. 79. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-38849188806&partnerID=MN8TOARS . 10.1136/jnnp.2007.128389 . Journal of Neurology, Neurosurgery and Psychiatry

Regulation by glucose of oscillatory electrical activity and 5-HT/insulin release from single mouse pancreatic islets in absence of functional K ATP channels

Rosário, L.M.; Barbosa, R.M.; Antunes, C.M.; Baldeiras, I.E.; Silva, A.M.; Tomé, Â.R.; Santos, R.M., Endocrine Journal. 639 - 650. 4. 55. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-51449090932&partnerID=MN8TOARS . 10.1507/endocrj.K07E-131 . Endocrine Journal

Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet

Machado, M.V.; Ravasco, P.; Jesus, L.; Marques-Vidal, P.; Oliveira, C.R.; Proença, T.; Baldeiras, I.; Camilo, M.E.; Cortez-Pinto, H., Scandinavian Journal of Gastroenterology. 95 - 102. 1. 43. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-37549069361&partnerID=MN8TOARS . 10.1080/00365520701559003 . Scandinavian Journal of Gastroenterology

Lamotrigine pharmacokinetic evaluation in epileptic patients submitted to VEEG monitoring

Almeida, A.M.; Falcão, A.C.; Sales, F.; Baldeiras, I.; Rocha, M.J.; Caramona, M.M., European Journal of Clinical Pharmacology. 737 - 742. 9. 62. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747888290&partnerID=MN8TOARS . 10.1007/s00228-006-0144-9 . European Journal of Clinical Pharmacology

Protein kinase C isoform specificity of cholinergic potentiation of glucose-induced pulsatile 5-HT/insulin release from mouse pancreatic islets

Baldeiras, I.E.; Santos, R.M.; Rosário, L.M., Biological Research. 531 - 539. 3. 39. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33751108741&partnerID=MN8TOARS . Biological Research

All projects

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Information of exclusive responsibility of the researcher 26-06-2022 , from platform CIÊNCIAVITAE.

2022/01 - 2023/06

Non-invasive biomarkers of brain AD pathology at pre-dementia stages

EXPL/MEC-NEU/0192/2021

Principal investigator

Funders: Fundação para a Ciência e a Tecnologia

2021 - 2023

Evaluating the impact of high-efficacy treatments on disease control in early MS: beyond NEDA

N/A

Researcher

2021/09 - 2022/12

Optical fingerprinting as a new tool for stratification of Alzheimer’s disease patients using blood-derived samples

N/A

Principal investigator

2021 - 2023

Evaluating the impact of high-efficacy treatments on disease control in early MS: beyond NEDA

N/A

Researcher

2021 - 2024

Assessing the value of serum Neurofilament light chain as biomarkers of response to first-line oral treatments in Multiple Sclerosis

NA

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Biogen Inc

2021/01/01 - 2021/12/31

Screening for neurodegeneration in an elderly cohort from the community: blood Neurofilament light chain as a tool to identify individuals at risk of cognitive decline

NA

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Grupo de Estudos de Envelhecimento Cerebral e Demencia

2021/01/01 - 2023/12/31

Disease modelling of frontotemporal dementia in human brain organoids

PTDC/MEC-NEU/4814/2020

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2021 - 2024

Assessing the value of serum Neurofilament light chain as biomarkers of response to first-line oral treatments in Multiple Sclerosis

NA

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Biogen Inc

2019 - 2022

Emerging MS therapies to the test: tracking immune cell trafficking, induced molecular mechanisms and aftermath effects

GZ-2017-11730

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Sanofi Genzyme

2018 - 2021

Beyond Beta-Amyloid - Deciphering Early Pathogenic Changes in Alzheimer's disease

PTDC/MED-NEU/27946/2017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018 - 2021

Affective disorders: biomarkers and early detection

POCI-01-0145-FEDER-30943

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2017 - 2020

Synaptic networks and Personalized Medicine Approaches to Understand Neurobehavioural Diseases Across the Lifespan

SAICTPAC/0010/2015

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2017 - 2018

New BACE1 inhibitors for the treatment of Alzheimer's disease: an approach for the development of effective and safe substrate-selective inhibitors

NA

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Grupo de Estudos de Envelhecimento Cerebral e Demencia

2016 - 2019

Novel cerebrospinal fluid and serum biomarkers for Multiple Sclerosis

RG-1601-07502

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: National Multiple Sclerosis Society

2016 - 2019

Schizophrenia diagnosis and prognosis: finding the way to a personalized medicine’’

PTDC/NEU-SCC/7051/2014

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012 - 2015

BIOMARKAPD: Biomarkers for Alzheimer´s disease and Parkinson’s disease

JPND/0005/2011

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012 - 2015

DEMTEST: Biomarker based diagnosis of rapid progressive dementias – optimisation of diagnostic protocols

JPND/0001/2011

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2009 - 2012

Early Diagnosis of Alzheimer´s Disease: evaluation of recent classification criteria and proposal of new diagnostic tools

PIC/IC/83206/2007

Researcher

Centro Hospitalar e Universitário de Coimbra EPE

Funders: Fundação para a Ciência e a Tecnologia

2007 - 2010

Identification of biomarkers for Multiple Sclerosis in the cerebrospinal fluid and serum

NA

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Biogen-Idec

2007 - 2009

Disrupção da barreira hemato-encefálica na Esclerose Múltipla

NA

Principal investigator

Centro Hospitalar e Universitário de Coimbra EPE

Funders: Biogen-Idec

2005 - 2008

Neo-neurogenesis and Microglia in Temporal Lobe Epilesy: Role of Pro-inflammatory Cytokines and Neuropeptide Y in Neuroprotection of New Neurons

POCTI/SAU-FCF/58492/2004

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2001 - 2003

KATP channel-dependent and independent pathways in pancreatic beta-cells from normal and non-obese type-3 diabetic rodents

POCTI/NSE/42123/2001

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

1998 - 2001

Molecular and ionic mechanisms underlying pulsatile insulin secretion

PRAXIS/C/SAU/1318/98

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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