Luisa Cortes

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Researcher

Overview

Luísa Cortes, PhD (female), is the head of the Microscopy Imaging Center of Coimbra (MICC), since 2007. Luísa has been involved in the implementation of new imaging methodology and imaging analysis protocols at CNC, which is well reflected in the number of collaborative publications in the last years. She is the Centro Polo coordinator of the PPBI - Portuguese Platform of BioImaging, integrated in the national RI roadmap, and a Euro-BioImaging stakeholder.

Affiliation

Center for Neuroscience and Cell Biology; Institute of Interdisciplinary Research of the University of Coimbra

Publications

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Information about journal articles, updated at 17-12-2023, from platform CIÊNCIAVITAE.

Isolation of Adeno-associated Viral Vectors Through a Single-step and Semi-automated Heparin Affinity Chromatography Protocol

Nobre, Rui Jorge; Pereira de Almeida, Luis Fernando Morgado, JoVE Journal. e66550. 2024. https://www.jove.com/t/66550 . in press JoVE Journal

Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome

Marisa Ferreira-Marques; André Carvalho; Ana Catarina Franco; Ana Leal; Mariana Botelho; Sara Carmo-Silva; Rodolfo Águas; et al, Aging Cell. 2023. https://doi.org/10.1111/acel.13983 . 10.1111/acel.13983 . Aging Cell

CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell Activation and Th1 Polarization

Ana Isabel Sebastião; Daniela Mateus; Mylène A. Carrascal; Cátia Sousa; Luísa Cortes; Martin F. Bachmann; Anália do Carmo; et al, Pharmaceutics. 2023. https://doi.org/10.3390/pharmaceutics15030825 . 10.3390/pharmaceutics15030825 . Pharmaceutics

Leptin enhances progerin clearance and ameliorates the senescent phenotype of human Hutchinson-Gilford Progeria Syndrome cells (under submission))

Real, AC; Ferreira-Marques, M; Cortes, Luisa; Cavadas, Cláudia; Aveleira, Célia A, 2022. submitted

Protective role of Portuguese natural mineral waters on skin aging: in vitro evaluation of anti-senescence and anti-oxidant properties

CV Vaz; AS Oliveira; A Silva; L Cortes; S Correia; R Ferreira; L Breitenfeld; et al, International Journal of Biometeorology. 2117 - 2131. 10. 66. 2022. http://dx.doi.org/10.1007/s00484-022-02345-8 . 10.1007/s00484-022-02345-8 . International Journal of Biometeorology

A new protocol for whole-brain biodistribution analysis of AAVs by tissue clearing, light-sheet microscopy and semi-automated spatial quantification

Miguel Lopes; Jacques Paysan; José Rino; Sara Monteiro Lopes; Pereira de Almeida L; Luísa Cortes; Nobre RJ, Gene Therapy. 665 - 679. 12. 29. 2022. http://dx.doi.org/10.1038/s41434-022-00372-z . 10.1038/s41434-022-00372-z . Gene Therapy

Spotted Fever Group <i>Rickettsia</i> Trigger Species-Specific Alterations in Macrophage Proteome Signatures with Different Impacts in Host Innate Inflammatory Responses

Curto, Pedro; Santa, Cátia; Cortes, Luisa; Manadas, Bruno; Simões, Isaura, Microbiology Spectrum. 3. 9. 2021. http://dx.doi.org/10.1128/spectrum.00814-21 . 10.1128/spectrum.00814-21 . Microbiology Spectrum

Tacrine – Benzothiazoles: Novel class of potential multitarget anti-Alzheimers drugs dealing with cholinergic, amyloid and mitochondrial systems

Nepovimova, Eugenie; Svobodova, Lucie; Dolezal, Rafael; Hepnarova, Vendula; Junova, Lucie; Jun, Daniel; Korabecny, Jan; et al, Bioorganic Chemistry. 107. 2021. http://dx.doi.org/10.1016/j.bioorg.2020.104596 . 10.1016/j.bioorg.2020.104596 . Bioorganic Chemistry

Using amyloid autofluorescence as a biomarker for lysozyme aggregation inhibition

Jesus, Catarina S. H.; Soares, Helder T.; Piedade, Ana P.; Cortes, Luísa; Serpa, Carlos, The Analyst. 2021. http://dx.doi.org/10.1039/d0an02260h . 10.1039/d0an02260h . accepted The Analyst

Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation

Luís F. Ribeiro; Tatiana Catarino; Mário Carvalho; Luísa Cortes; Sandra D. Santos; Patricio O. Opazo; Lyn Rosenbrier Ribeiro; et al, Science Signaling. 2021. https://doi.org/10.1126/scisignal.abb1953 . 10.1126/scisignal.abb1953 . Science Signaling

Calcium Signaling in Aging and Neurodegenerative Diseases 2019

Luísa Cortes; João Malva; Ana Cristina Rego; Cláudia F. Pereira, International Journal of Molecular Sciences. 1125 - 1125. 3. 21. 2020. https://doi.org/10.3390/ijms21031125 . 10.3390/ijms21031125 . International Journal of Molecular Sciences

Pollen Proteases Play Multiple Roles in Allergic Disorders

Gaspar, Ricardo; Cortes, Luisa; Nunes-Correia, Isabel; Todo-Bom, Ana; Pires, Euclides; Paula Veríssimo, International Journal of Molecular Sciences. 2020. http://dx.doi.org/10.3390/ijms21103578 . 10.3390/ijms21103578 . International Journal of Molecular Sciences

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells

Aveleira, Célia A; Ferreira-Marques, Marisa; Cortes, Luísa; Valero, Jorge; Pereira, Dina; Pereira de Almeida, Luís; Cavadas, Cláudia, The Journals of Gerontology: Series A. 2020. http://dx.doi.org/10.1093/gerona/glz280 . 10.1093/gerona/glz280 . accepted The Journals of Gerontology: Series A

Ischaemia impacts TNT-mediated communication between cardiac cells

Daniela Batista-Almeida; Teresa Ribeiro-Rodrigues; Tânia Martins-Marques; Luisa Cortes; Manuel J. Antunes; Pedro E. Antunes; Lino Gonçalves; et al, Current Research in Cell Biology. 100001 - 100001. 1. 2020. https://doi.org/10.1016/j.crcbio.2020.04.001 . 10.1016/j.crcbio.2020.04.001 . Current Research in Cell Biology

Ischaemia impacts on TNT-mediated communication between cardiac cells

Batista-Almeida, Daniela; Ribeiro-Rodrigues, Teresa; Martins-Marques, Tânia; Cortes, Luisa; Antunes, Manuel J; Antunes, Pedro E; Gonçalves, Lino; et al, Current Research in Cell Biology (accepted for publication). 2020. Current Research in Cell Biology (accepted for publication)

BDNF increases synaptic NMDA receptor abundance by enhancing the local translation of Pyk2 in cultured hippocampal neurons

Pedro Afonso; Pasqualino De Luca; Rafael S. Carvalho; Luísa Cortes; Paulo Pinheiro; Barbara Oliveiros; Ramiro D. Almeida; Miranda Mele; Carlos B. Duarte, Science Signaling. eaav3577 - eaav3577. 586. 12. 2019. https://doi.org/10.1126/scisignal.aav3577 . 10.1126/scisignal.aav3577 . Science Signaling

Targeting of Cellular Organelles by Fluorescent Plasmid DNA Nanoparticles

Diana Costa; Carolina Costa; Margarida Caldeira; Luísa Cortes; João A. Queiroz; Carla Cruz, Biomacromolecules. 2928 - 2936. 9. 18. 2017. https://doi.org/10.1021/acs.biomac.7b00877 . 10.1021/acs.biomac.7b00877 . Biomacromolecules

Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderly.

Rodrigues L; Miranda IM; Andrade GM; Mota M; Cortes L; Rodrigues AG; Cunha RA; Gonçalves T, 2016. http://europepmc.org/abstract/med/27590517 . 10.18632/oncotarget.11760 .

Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation.

Rocha SM; Saraiva T; Cristóvão AC; Ferreira R; Santos T; Esteves M; Saraiva C; et al, 2016. http://europepmc.org/abstract/med/27260166 . 10.1186/s12974-016-0600-0 .

Neuropeptide Y stimulates autophagy in hypothalamic neurons.

Aveleira CA; Botelho M; Carmo-Silva S; Pascoal JF; Ferreira-Marques M; Nóbrega C; Cortes L; et al, 2015. http://europepmc.org/abstract/med/25775546 . 10.1073/pnas.1416609112 .

Modulation of Alternaria infectoria Cell Wall Chitin and Glucan Synthesis by Cell Wall Synthase Inhibitors.

Fernandes C; Anjos J; Walker LA; Silva BM; Cortes L; Mota M; Munro CA; Gow NA; Gonçalves T, 2014. http://europepmc.org/abstract/med/24614372 . 10.1128/AAC.02647-13 .

Histamine stimulates neurogenesis in the rodent subventricular zone

Bernardino, L.; Eiriz, M.F.; Santos, T.; Xapelli, S.; Grade, S.; Rosa, A.I.; Cortes, L.; et al, Stem Cells. 773 - 784. 4. 30. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859512101&partnerID=MN8TOARS . 10.1002/stem.1042 . Stem Cells

Neuropeptide y inhibits interleukin-1 beta-induced microglia motility

Ferreira, R.; Santos, T.; Cortes, L.; Cochaud, S.; Agasse, F.; Silva, A.P.; Xapelli, S.; Malva, J.O., Journal of Neurochemistry. 93 - 105. 1. 120. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-83855162714&partnerID=MN8TOARS . 10.1111/j.1471-4159.2011.07541.x . Journal of Neurochemistry

Polymeric nanoparticles to control the differentiation of neural stem cells in the subventricular zone of the brain

Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragancia, J.; et al, ACS Nano. 10463 - 10474. 12. 6. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871596644&partnerID=MN8TOARS . 10.1021/nn304541h . ACS Nano

Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

Arduíno, D.M.; Esteves, A.R.; Cortes, L.; Silva, D.F.; Patel, B.; Grazina, M.; Swerdlow, R.H.; Oliveira, C.R.; Cardoso, S.M., Human Molecular Genetics. 4680 - 4702. 21. 21. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867828156&partnerID=MN8TOARS . 10.1093/hmg/dds309 . Human Molecular Genetics

Valosin-Containing Protein (VCP/p97) Is an Activator of Wild-Type Ataxin-3

Laço, M.N.; Cortes, L.; Travis, S.M.; Paulson, H.L.; Rego, A.C., PLoS ONE. 9. 7. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866103154&partnerID=MN8TOARS . 10.1371/journal.pone.0043563 . PLoS ONE

Presynaptic CB1 cannabinoid receptors control frontocortical serotonin and glutamate release - Species differences

Ferreira, S.G.; Teixeira, F.M.; Garção, P.; Agostinho, P.; Ledent, C.; Cortes, L.; MacKie, K.; Köfalvi, A., Neurochemistry International. 219 - 226. 2. 61. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863463752&partnerID=MN8TOARS . 10.1016/j.neuint.2012.05.009 . Neurochemistry International

Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: Evidence from intracellular fluorescence and increased photodynamic efficacy in vitro

Da¸browski, J.M.; Arnaut, L.G.; Pereira, M.M.; Urbanska, K.; Simões, S.; Stochel, G.; Cortes, L., Free Radical Biology and Medicine. 1188 - 1200. 7. 52. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857920394&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2011.12.027 . Free Radical Biology and Medicine

Controlling the neuronal differentiation of stem cells by the intracellular delivery of retinoic acid-loaded nanoparticles

Maia, J.; Santos, T.; Aday, S.; Agasse, F.; Cortes, L.; Malva, J.O.; Bernardino, L.; Ferreira, L., ACS Nano. 97 - 106. 1. 5. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955113748&partnerID=MN8TOARS . 10.1021/nn101724r . ACS Nano

Neuropeptide Y inhibits interleukin-1ß-induced phagocytosis by microglial cells

Ferreira, R.; Santos, T.; Viegas, M.; Cortes, L.; Bernardino, L.; Vieira, O.V.; Malva, J.O., Journal of Neuroinflammation. 8. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-82455168238&partnerID=MN8TOARS . 10.1186/1742-2094-8-169 . Journal of Neuroinflammation

Functional Identification of Cell Phenotypes Differentiating from Mice Retinal Neurospheres Using Single Cell Calcium Imaging

De Melo Reis, R.A.; Schitine, C.S.; Kofalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., Cellular and Molecular Neurobiology. 1 - 12. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952606231&partnerID=MN8TOARS . 10.1007/s10571-011-9673-6 . Cellular and Molecular Neurobiology

Functional identification of cell phenotypes differentiating from mice retinal neurospheres using single cell calcium imaging.

De Melo Reis, R.A.; Schitine, C.S.; Köfalvi, A.; Grade, S.; Cortes, L.; Gardino, P.F.; Malva, J.O.; de Mello, F.G., Cellular and molecular neurobiology. 835 - 846. 6. 31. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856384867&partnerID=MN8TOARS . Cellular and molecular neurobiology

Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides

Vinhas, R.; Cortes, L.; Cardoso, I.; Mendes, V.M.; Manadas, B.; Todo-Bom, A.; Pires, E.; Veríssimo, P., Allergy: European Journal of Allergy and Clinical Immunology. 1088 - 1098. 8. 66. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960015037&partnerID=MN8TOARS . 10.1111/j.1398-9995.2011.02598.x . Allergy: European Journal of Allergy and Clinical Immunology

Functional identification of neural stem cell-derived oligodendrocytes by means of calcium transients elicited by thrombin

Grade, S.; Agasse, F.; Bernardino, L.; Silva, C.G.; Cortes, L.; Malva, J.O., Rejuvenation Research. 27 - 37. 1. 13. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949493309&partnerID=MN8TOARS . 10.1089/rej.2009.0889 . Rejuvenation Research

The angiogenic factor angiopoietin-1 is a proneurogenic peptide on subventricular zone stem/progenitor cells

Rosa, A.I.; Gonçalves, J.; Cortes, L.; Bernardino, L.; Malva, J.O.; Agasse, F., Journal of Neuroscience. 4573 - 4584. 13. 30. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950633340&partnerID=MN8TOARS . 10.1523/JNEUROSCI.5597-09.2010 . Journal of Neuroscience

Neuropeptide y modulation of interleukin-1ß (IL-1ß)-induced nitric oxide production in microglia

Ferreira, R.; Xapelli, S.; Santos, T.; Silva, A.P.; Cristóvão, A.; Cortes, L.; Malva, J.O., Journal of Biological Chemistry. 41921 - 41934. 53. 285. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650658398&partnerID=MN8TOARS . 10.1074/jbc.M110.164020 . Journal of Biological Chemistry

Nucleocytoplasmic Shuttling Activity of Ataxin-3

Macedo-Ribeiro, Sandra; Cortes, Luísa; Maciel, Patrícia; Carvalho, Ana Luísa, PLoS ONE. 6. 4. 2009. http://dx.doi.org/10.1371/journal.pone.0005834 . 10.1371/journal.pone.0005834 . PLoS ONE

NEDD8: A new ataxin-3 interactor

Ferro, A.; Carvalho, A.L.; Teixeira-Castro, A.; Almeida, C.; Tomé, R.J.; Cortes, L.; Rodrigues, A.-J.; et al, Biochimica et Biophysica Acta - Molecular Cell Research. 1619 - 1627. 11. 1773. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35548938484&partnerID=MN8TOARS . 10.1016/j.bbamcr.2007.07.012 . Biochimica et Biophysica Acta - Molecular Cell Research

Purification of a novel aminopeptidase from the pollen of Parietaria judaica that alters epithelial integrity and degrades neuropeptides

Cortes, L.; Carvalho, A.L.; Todo-Bom, A.; Faro, C.; Pires, E.; Veríssimo, P., Journal of Allergy and Clinical Immunology. 878 - 884. 4. 118. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33749349447&partnerID=MN8TOARS . 10.1016/j.jaci.2006.05.029 . Journal of Allergy and Clinical Immunology

Towards a structural understanding of the fibrillization pathway in Machado-Joseph's disease: Trapping early oligomers of non-expanded ataxin-3

Gales, L.; Cortes, L.; Almeida, C.; Melo, C.V.; Costa, M.D.C.; Maciel, P.; Clarke, D.T.; et al, Journal of Molecular Biology. 642 - 654. 3. 353. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-26244434741&partnerID=MN8TOARS . 10.1016/j.jmb.2005.08.061 . Journal of Molecular Biology

Identification of the pgmG gene, encoding a bifunctional protein with phosphoglucomutase and phosphomannomutase activities, in the gellan gum- producing strain Sphingomonas paucimobilis ATCC 31461

Videira, P.A.; Cortes, L.L.; Fialho, A.M.; Sá-Correia, I., Applied and Environmental Microbiology. 2252 - 2258. 5. 66. 2000. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034016761&partnerID=MN8TOARS . 10.1128/AEM.66.5.2252-2258.2000 . Applied and Environmental Microbiology

Identification and proteolytic processing of procardosin A

Ramalho-Santos, M.; Verissimo, P.; Cortes, L.; Samyn, B.; Beeumen, J.V.; Pires, E.; Faro, C., European Journal of Biochemistry. 133 - 138. 1. 255. 1998. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032127477&partnerID=MN8TOARS . 10.1046/j.1432-1327.1998.2550133.x . European Journal of Biochemistry

All projects

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Information of exclusive responsibility of the researcher 17-12-2023 , from platform CIÊNCIAVITAE.

2023/03/01 - 2024/08/31

A New TransSynaptic Bridge: Functional characterization of the NMDA receptor-Neurexin interaction

2022.05386.PTDC

Researcher

Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2022/05/03 - 2023/04/30

(Less)PlasticBrain: Bio Replacing Plasticizers – Impact in the Human Brain Development

N/A

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Universidade de Coimbra

2021/01/01 - 2025/12/31

Centro de Inovação em Biomedicina e Biotecnologia - Laboratório Associado

LA/P/0058/2020

Researcher

Universidade de Coimbra; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2021/01/01 - 2025/12/31

Center for Innovative Biomedicine and Biotechnology - Associate Laboratory

10.54499/LA/P/0058/2020

Universidade de Coimbra; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2020/11/16 - 2021/07/15

TecniCOV –Desenvolvimentode testes rápidos para monitorização de anticorpos em soro e saliva

TecniCOV, número 69745

Researcher

Universidade de Coimbra

Funders: Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização

2019/01/01 - 2019/12/31

CNC. IBILI

UID/NEU/04539/2019

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra; Universidade de Coimbra Instituto de Ciências Nucleares Aplicadas à Saúde; Universidade de Coimbra Instituto de Investigação Clínica e Biomédica de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2016/01 - 2019/12

Imaging Gene Therapy in the Brain

Provided by PTCRIS: 139557

Principal investigator

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2014/04/01 - 2015/09/30

Hunger wisdom: ghrelin modulation of adult neurogenesis and its relationship with memory

EXPL/NEU-SCC/1193/2013

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2013/07/01 - 2015/11/30

Effects of the orexigenic peptide ghrelin on glutamatergic synaptic transmission

PTDC/NEU-NMC/1098/2012

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2012 - 2012

Effect of the orexigenic peptide ghrelin on AMPA receptors levels at the synapse

EMBO Short-term fellowship - ASTF 126 2012

Funders: N/A

2011/01/01 - 2014/06/30

Regulation by phosphorylation of ataxin-3, the mutated protein in Machado Joseph Disease

PTDC/SAU-NMC/110602/2009

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade do Minho

Funders: Fundação para a Ciência e a Tecnologia

2011/01/01 - 2012/12/31

Strategic Project - LA 1 - 2011-2012

PEst-C/SAU/LA0001/2011

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03/17 - 2012/07/31

Mapping the metabolic and neuromodulator role of insulin in the hippocampus

PTDC/SAU-OSM/105663/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/03/17 - 2012/06/16

Demonstrating that A2A adenosine receptors control glutamatergic synaptic plasticity through CB1 cannabinoid receptors in the striatum, thus providing attracting therapeutic targets

PTDC/SAU-NEU/100729/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/04/01 - 2013/06/30

Role of intercellular communication between endothelial and stem cells in stemness and neurogenesis: new targets for brain repair therapies.

PTDC/SAU-NEU/101783/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/04/01 - 2013/03/31

Histamine versus antihistamines: new modulators of neurogenesis?

PTDC/SAU-NEU/104415/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2010/04/01 - 2013/07/15

Effect of caffeine and adenosine A2A receptors on stress response: role of adrenal gland modulation

PTDC/SAU-NEU/108110/2008

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2008/04/01 - 2012/03/31

PROFILING ATAXIN-3 UBIQUITIN PROTEASE ACTIVITY: A BIOCHEMICAL AND STRUCTURAL APPROACH

PTDC/BIA-PRO/70455/2006

Research Fellow

Funders: Fundação para a Ciência e a Tecnologia

2008/05/23 - 2012/05/22

Pollen proteases, role in allergic disorders

PTDC/SAU-ESA/72571/2006

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra

Funders: Fundação para a Ciência e a Tecnologia

2005/06/01 - 2008/12/31

Molecular determinants of ataxin-3 aggregation and toxicity in Machado-Joseph´s disease

POCI/SAU-MMO/60156/2004

Research Fellow

Universidade do Porto Instituto de Biologia Molecular e Celular; Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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