Publications
Information about journal articles, updated at 05-12-2021, from platform CIÊNCIAVITAE.
Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
Esteves AR; Alarico S, Gut. 1 - 20211. 2021. http://dx.doi.org/10.1136/gutjnl-2021-326023 . 10.1136/gutjnl-2021-326023 . published Gut
The neuromicrobiology of Parkinson's disease: A unifying theory
Muñoz-Pinto MF, Ageing Research Reviews. 70. 2021. http://dx.doi.org/10.1016/j.arr.2021.101396 . 10.1016/j.arr.2021.101396 . published Ageing Research Reviews
Improved diabetic wound healing by bovine lactoferricin is associated with relevant changes in the skin immune response and microbiota
Mouritzen MV, Molecular Therapy - Methods & Clinical Development. 726 - 739. 20. 2021. https://doi.org/10.1016/j.omtm.2021.02.008 . 10.1016/j.omtm.2021.02.008 . published Molecular Therapy - Methods & Clinical Development
The Mitochondrial Ribosome: A World of Opportunities for Mitochondrial Dysfunction Toward Parkinson's Disease
Gonçalves AM, Antioxidants & Redox Signaling. 694 - 711. 8. 34. 2021. https://www.liebertpub.com/doi/10.1089/ars.2019.7997 . 10.1089/ars.2019.7997 . published Antioxidants & Redox Signaling
Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation and Alzheimer's disease features in cortical neurons
Silva DF, Journal of Neuroinflammation. 332. 17. 2020. http://dx.doi.org/10.1186/s12974-020-02004-y . 10.1186/s12974-020-02004-y . published Journal of Neuroinflammation
Editorial: Interplay Between Nutrition, the Intestinal Microbiota and the Immune System
Oriá RB, Frontiers in Immunology. 11. 2020. http://dx.doi.org/10.3389/fimmu.2020.01758 . 10.3389/fimmu.2020.01758 . published Frontiers in Immunology
Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers
Silva MB; Färnert A, Journal of Immunological Methods. 481. 2020. http://dx.doi.org/10.1016/j.jim.2020.112792 . 10.1016/j.jim.2020.112792 . published Journal of Immunological Methods
A genuine mycobacterial thermophile: Mycobacterium hassiacum growth, survival and GpgS stability at near-pasteurization temperatures
Alarico S, Microbiology. 474 - 483. 5. 166. 2020. http://dx.doi.org/10.1099/mic.0.000898 . 10.1099/mic.0.000898 . published Microbiology
Microbial BMAA and the Pathway for Parkinson's Disease Neurodegeneration
Nunes-Costa D, Frontiers in Aging Neuroscience. 12. 2020. https://doi.org/10.3389/fnagi.2020.00026 . 10.3389/fnagi.2020.00026 . published Frontiers in Aging Neuroscience
The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation
Cereija TB, IUCrJ. 572 - 585. 4. 6. 2019. https://doi.org/10.1107/S2052252519005372 . 10.1107/S2052252519005372 . published IUCrJ
High-Quality Draft Genome Sequences of Rare Nontuberculous Mycobacteria Isolated from Surfaces of a Hospital
Tiago I, Microbiology Resource Announcements. 21. 8. 2019. https://doi.org/10.1128/MRA.00496-19 . 10.1128/MRA.00496-19 . published Microbiology Resource Announcements
Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides
Ripoll-Rozada J; Pereira PJB; Empadinhas N, Proceedings of the National Academy of Sciences. 201813450 - 201813450. 2019. https://www.pnas.org/content/116/3/835.long . 10.1073/pnas.1813450116 . published Proceedings of the National Academy of Sciences
Studies of antimicrobial resistance in rare mycobacteria from a nosocomial environment
Pereira SG, BMC Microbiology. 1. 19. 2019. http://dx.doi.org/10.1186/s12866-019-1428-4 . 10.1186/s12866-019-1428-4 . published BMC Microbiology
Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity
Manso JA, mBio. 2019. https://doi.org/10.1128/mBio.00239-19 . 10.1128/mBio.00239-19 . published mBio
The Microbiome-Mitochondria Dance in Prodromal Parkinson’s Disease
Cardoso SM, Empadinhas N, Frontiers in Physiology. 9. 2018. https://www.frontiersin.org/articles/10.3389/fphys.2018.00471/full . 10.3389/fphys.2018.00471 . published Frontiers in Physiology
Production, crystallization and structure determination of a mycobacterial glucosylglycerate hydrolase
Cereija TB, Acta Crystallographica Section F Structural Biology Communications. 536 - 540. 9. 73. 2017. https://doi.org/10.1107%2Fs2053230x17012419 . 10.1107/S2053230X17012419 . published Acta Crystallographica Section F Structural Biology Communications
Hospital microbial surface colonization revealed during monitoring of Klebsiella spp., Pseudomonas aeruginosa, and non-tuberculous mycobacteria
Farias PG, Antonie van Leeuwenhoek. 863 - 876. 7. 110. 2017. http://dx.doi.org/10.1007/s10482-017-0857-z . 10.1007/s10482-017-0857-z . published Antonie van Leeuwenhoek
Microbiota of Chronic Diabetic Wounds: Ecology, Impact, and Potential for Innovative Treatment Strategies
Pereira SG, Frontiers in Microbiology. 8. 2017. https://doi.org/10.3389%2Ffmicb.2017.01791 . 10.3389/fmicb.2017.01791 . published Frontiers in Microbiology
Glucosylglycerate metabolism, bioversatility and mycobacterial survival
Nunes-Costa D, Glycobiology. 213 - 227. 27. 2016. http://dx.doi.org/10.1093/glycob/cww132 . 10.1093/glycob/cww132 . published Glycobiology
The looming tide of nontuberculous mycobacterial infections in Portugal and Brazil
Nunes-Costa D, Tuberculosis. 107 - 119. 96. 2016. http://dx.doi.org/10.1016/j.tube.2015.09.006 . 10.1016/j.tube.2015.09.006 . published Tuberculosis
Octanoylation of early intermediates of mycobacterial methylglucose lipopolysaccharides
Maranha A; Clarke AJ, Empadinhas N, Scientific Reports. 1. 5. 2015. http://dx.doi.org/10.1038/srep13610 . 10.1038/srep13610 . published Scientific Reports
Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway
Fraga JS, Scientific Reports. 5. 2015. https://doi.org/10.1038/srep08026 . 10.1038/srep08026 . published Scientific Reports
Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism
Mendes V, Scientific Reports. 1. 5. 2015. http://dx.doi.org/10.1038/srep17144 . 10.1038/srep17144 . published Scientific Reports
The molecular biology of mycobacterial trehalose in the quest for advanced tuberculosis therapies
Nobre A, Microbiology (United Kingdom). 1547 - 1570. PART 8. 160. 2014. https://doi.org/10.1099/mic.0.075895-0 . 10.1099/mic.0.075895-0 . published Microbiology (United Kingdom)
Autophagy in the fight against tuberculosis
Bento CF, DNA and Cell Biology. 228 - 242. 4. 34. 2014. https://doi.org/10.1089/dna.2014.2745 . 10.1089/dna.2014.2745 . published DNA and Cell Biology
Mycobacterium hassiacum recovers from nitrogen starvation with up-regulation of a novel glucosylglycerate hydrolase and depletion of the accumulated glucosylglycerate
Alarico S, Scientific Reports. 1. 4. 2014. http://dx.doi.org/10.1038/srep06766 . 10.1038/srep06766 . published Scientific Reports
A new bacterial hydrolase specific for the compatible solutes alpha-D-mannopyranosyl-(1,2)-D-glycerate and alpha-D-glucopyranosyl-(1,2)-D-glycerate
Alarico S, Enzyme and Microbial Technology. 77 - 83. 2. 52. 2013. http://dx.doi.org/10.1016/j.enzmictec.2012.10.008 . 10.1016/j.enzmictec.2012.10.008 . published Enzyme and Microbial Technology
The plant Selaginella moellendorffii possesses enzymes for synthesis and hydrolysis of the compatible solutes mannosylglycerate and glucosylglycerate
Nobre A, Planta. 891 - 901. 3. 237. 2013. https://doi.org/10.1007/s00425-012-1808-6 . 10.1007/s00425-012-1808-6 . published Planta
Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of heat-stable mycobacterial proteins
Tiago I, Journal of Bacteriology. 7010 - 7011. 24. 194. 2012. DOI: https://doi.org/10.1128/JB.01880-12 . 10.1128/JB.01880-12 . published Journal of Bacteriology
Biosynthesis of mycobacterial methylglucose lipopolysaccharides
Mendes V, Natural Product Reports. 834 - 844. 8. 29. 2012. https://doi.org/10.1039/C2NP20014G . 10.1039/c2np20014g . published Natural Product Reports
Mycobacterium tuberculosis Rv2419c, the missing glucosyl-3-phosphoglycerate phosphatase for the second step in methylglucose lipopolysaccharide biosynthesis
Mendes V, Scientific Reports. 1. 1. 2011. http://dx.doi.org/10.1038/srep00177 . 10.1038/srep00177 . published Scientific Reports
Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity
Empadinhas N, Molecular Microbiology. 76 - 93. 1. 79. 2011. https://doi.org/10.1111/j.1365-2958.2010.07432.x . 10.1111/j.1365-2958.2010.07432.x . published Molecular Microbiology
Diversity, biological roles and biosynthetic pathways for sugar-glycerate containing compatible solutes in bacteria and archaea
Empadinhas N, da Costa MS, Environmental Microbiology. 2056 - 2077. 8. 13. 2011. https://doi.org/10.1111/j.1462-2920.2010.02390.x . 10.1111/j.1462-2920.2010.02390.x . published Environmental Microbiology
Two alternative pathways for the synthesis of the rare compatible solute mannosylglucosylglycerate in Petrotoga mobilis
Fernandes C, Journal of Bacteriology. 1624 - 1633. 6. 192. 2010. https://doi.org/10.1128/JB.01424-09 . 10.1128/JB.01424-09 . published Journal of Bacteriology
Biochemical characterization of the maltokinase from Mycobacterium bovis BCG
Mendes V, BMC Biochemistry. 2010. https://doi.org/10.1186/1471-2091-11-21 . 10.1186/1471-2091-11-21 . published BMC Biochemistry
Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase
Empadinhas N, FEMS Microbiology Letters. 195 - 202. 2. 280. 2008. https://doi.org/10.1111/j.1574-6968.2007.01064.x . 10.1111/j.1574-6968.2007.01064.x . published FEMS Microbiology Letters
Crystallization and preliminary crystallographic analysis of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus
Sá-Moura B, Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 760 - 763. 8. 64. 2008. https://doi.org/10.1107/S1744309108021490 . 10.1107/S1744309108021490 . published Acta Crystallographica Section F: Structural Biology and Crystallization Communications
To be or not to be a compatible solute: Bioversatility of mannosylglycerate and glucosylglycerate
Empadinhas N, da Costa MS, Systematic and Applied Microbiology. 159 - 168. 3. 31. 2008. https://doi.org/10.1016/j.syapm.2008.05.002 . 10.1016/j.syapm.2008.05.002 . published Systematic and Applied Microbiology
Osmoadaptation mechanisms in prokaryotes: Distribution of compatible solutes
Empadinhas N, da Costa MS, International Microbiology. 151 - 161. 3. 11. 2008. https://europepmc.org/article/med/18843593 . 10.2436/20.1501.01.55 . published International Microbiology
Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: Structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis
Pereira PJB, PLoS ONE. 11. 3. 2008. https://doi.org/10.1371/journal.pone.0003748 . 10.1371/journal.pone.0003748 . published PLoS ONE
Molecular and physiological role of the trehalose-hydrolyzing a-glucosidase from Thermus thermophilus HB27
Alarico S, Journal of Bacteriology. 2298 - 2305. 7. 190. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-41549086172&partnerID=MN8TOARS . 10.1128/JB.01794-07 . published Journal of Bacteriology
A Unique Combination of Genetic Systems for the Synthesis of Trehalose in Rubrobacter xylanophilus: Properties of a Rare Actinobacterial TreT
Nobre A, Journal of Bacteriology. 7939 - 7946. 24. 190. 2008. http://dx.doi.org/10.1128/jb.01055-08 . 10.1128/jb.01055-08 . published Journal of Bacteriology
Bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol: Inositol-1-phosphate transferase, the key enzyme for di-myo-inositol-phosphate synthesis in several (hyper)thermophiles
Rodrigues MV, Journal of Bacteriology. 5405 - 5412. 15. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547629796&partnerID=MN8TOARS . 10.1128/JB.00465-07 . published Journal of Bacteriology
Glucosylglycerate biosynthesis in the deepest lineage of the Bacteria: Characterization of the thermophilic proteins GpgS and GpgP from Persephonella marina
Costa J, Journal of Bacteriology. 1648 - 1654. 5. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947366922&partnerID=MN8TOARS . 10.1128/JB.00841-06 . published Journal of Bacteriology
Single-step pathway for synthesis of glucosylglycerate in Persephonella marina
Fernandes C, Journal of Bacteriology. 4014 - 4019. 11. 189. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34249786874&partnerID=MN8TOARS . 10.1128/JB.00075-07 . published Journal of Bacteriology
Organic solutes in Rubrobacter xylanophilus: The first example of di-myo-inositol-phosphate in a thermophile
Empadinhas N, Extremophiles. 667 - 673. 5. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548303944&partnerID=MN8TOARS . 10.1007/s00792-007-0084-z . published Extremophiles
Mannosylglycerate is essential for osmotic adjustment in Thermus thermophilus strains HB27 and RQ-1
Alarico S, Extremophiles. 833 - 840. 6. 11. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-35748948644&partnerID=MN8TOARS . 10.1007/s00792-007-0106-x . published Extremophiles
Diversity and biosynthesis of compatible solutes in hyper/thermophiles
Empadinhas N, da Costa MS, International Microbiology. 199 - 206. 3. 9. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750584278&partnerID=MN8TOARS . published International Microbiology
Characterization of the biosynthetic pathway of glucosylglycerate in the archaeon Methanococcoides burtonii
Costa J, Journal of Bacteriology. 1022 - 1030. 3. 188. 2006. http://www.scopus.com/inward/record.url?eid=2-s2.0-31344453995&partnerID=MN8TOARS . 10.1128/JB.188.3.1022-1030.2006 . published Journal of Bacteriology
Distribution of genes for synthesis of trehalose and mannosylglycerate in Thermus spp. and direct correlation of these genes with halotolerance
Alarico S, Applied and Environmental Microbiology. 2460 - 2466. 5. 71. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-18444382346&partnerID=MN8TOARS . 10.1128/AEM.71.5.2460-2466.2005 . published Applied and Environmental Microbiology
Meiothermus timidus sp. nov., a new slightly thermophilic yellow-pigmented species
Pires AL, FEMS Microbiology Letters. 39 - 45. 1. 245. 2005. http://www.scopus.com/inward/record.url?eid=2-s2.0-15744405109&partnerID=MN8TOARS . 10.1016/j.femsle.2005.02.011 . published FEMS Microbiology Letters
Specialized Roles of the Two Pathways for the Synthesis of Mannosylglycerate in Osmoadaptation and Thermoadaptation of Rhodothermus marinus
Borges N, Journal of Biological Chemistry. 9892 - 9898. 11. 279. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-1642279326&partnerID=MN8TOARS . 10.1074/jbc.M312186200 . published Journal of Biological Chemistry
A gene from the mesophilic bacterium Dehalococcoides ethenogenes encodes a novel mannosylglycerate synthase
Empadinhas N, Journal of Bacteriology. 4075 - 4084. 13. 186. 2004. http://www.scopus.com/inward/record.url?eid=2-s2.0-3042523198&partnerID=MN8TOARS . 10.1128/JB.186.13.4075-4084.2004 . published Journal of Bacteriology
The Bacterium Thermus thermophilus , Like Hyperthermophilic Archaea, Uses a Two-Step Pathway for the Synthesis of Mannosylglycerate
Empadinhas N, Applied and Environmental Microbiology. 3272 - 3279. 6. 69. 2003. http://dx.doi.org/10.1128/aem.69.6.3272-3279.2003 . 10.1128/aem.69.6.3272-3279.2003 . published Applied and Environmental Microbiology
Gamma-Proteobacteria Aquicella lusitana gen. nov., sp. nov., and Aquicella siphonis sp. nov. Infect Protozoa and Require Activated Charcoal for Growth in Laboratory Media
Santos P, Applied and Environmental Microbiology. 6533 - 6540. 11. 69. 2003. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242573382&partnerID=MN8TOARS . 10.1128/AEM.69.11.6533-6540.2003 . published Applied and Environmental Microbiology
Rubritepida flocculans gen. nov., sp. nov., a New Slightly Thermophilic Member of the a-1 Subclass of the Proteobacteria
Alarico S, Systematic and Applied Microbiology. 198 - 206. 2. 25. 2002. http://dx.doi.org/10.1078/0723-2020-00116 . 10.1078/0723-2020-00116 . published Systematic and Applied Microbiology
Albidovulum inexpectatum gen. nov., sp. nov., a nonphotosynthetic and slightly thermophilic bacterium from a marine hot spring that is very closely related to members of the photosynthetic genus Rhodovulum
Albuquerque L, Applied and Environmental Microbiology. 4266 - 4273. 9. 68. 2002. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036729238&partnerID=MN8TOARS . 10.1128/AEM.68.9.4266-4273.2002 . published Applied and Environmental Microbiology
Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii: Biochemical and genetic characterization of key enzymes
Empadinhas N, Journal of Biological Chemistry. 43580 - 43588. 47. 276. 2001. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035941355&partnerID=MN8TOARS . 10.1074/jbc.M108054200 . published Journal of Biological Chemistry
Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase
Martins LO, Journal of Biological Chemistry. 35407 - 35414. 50. 274. 1999. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033544948&partnerID=MN8TOARS . 10.1074/jbc.274.50.35407 . published Journal of Biological Chemistry
5 59 out of 59 Publications
All projects
Information of exclusive responsibility of the researcher 05-12-2021 , from platform CIÊNCIAVITAE.
2022 - 2025
Nontuberculous mycobacteria from drinking water: beyond the lung disease epidemic (PI)
PTDC/BIA-MIC/0122/2021
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2022 - 2023
Microbiome-miRNAs axis in Parkinson's disease: involvement of mitochondrial mediated inflammatory response
EXPL/MED-NEU/1515/2021
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2025
CIBB - Center for Innovative Biomedicine and Biotechnology - Associate Laboratory (Institutional)
LA/P/0058/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2021 - 2025
DYNABrain - Dynamic Brain Function: Towards the Understanding and Treatment of Brain Disorders (ERA Chairs - Institutional)
H2020-WIDESPREAD-2018-2020-6, ID: 952422
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: European Commission
2021 - 2024
STOPD - The Gut-Immune-Brain Axis in Parkinson disease (Co-PI)
PTDC/MED-NEU/3644/2020
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2020 - 2023
CIBB - Center for Innovative Biomedicine and Biotechnology (Institutional)
UIDB/04539/2020 and UIDP/04539/2020
Researcher
Universidade de Coimbra Centro de Inovação em Biomedicina e Biotecnologia (CIBB)
Funders: Fundação para a Ciência e a Tecnologia
2020 - 2021
Sustainable and dual function polymeric edible films: a probiotic and antioxidant delivery food packaging system
Prémio Projetos Semente de I&D "Era pós-COVID 19: uma sociedade mais sustentável, resiliente e justa
Researcher
Universidade de Coimbra
Funders: Universidade de Coimbra/Santander
2018 - 2022
STERILAEROGEL - Green method to prepare sterilized biopolymers based aerogel
POCI-01-0145-FEDER-032625
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade de Coimbra Departamento de Engenharia Quimica
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2018
Prevalência de micobactérias não-tuberculosas em ambiente doméstico (Co-PI)
Prémio Thomé Villar/Boehringer Ingelheim 2017
Principal investigator
Universidade do Porto Instituto de Saúde Pública; Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Sociedade Portuguesa de Pneumologia; Boehringer Ingelheim Portugal
2018 - 2021
POLYREP - An intriguing mycobacterial polysaccharide: recycling, replication and beyond (PI)
PTDC/BTM-TEC/29221/2017
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2018 - 2018
The role of microbial metabolites in Parkinson's Disease
PEPITA Award 2018
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Faculdade de Medicina, Universidade de Coimbra & Banco Santander
2017 - 2021
HealthyAging2020 (WP9 - Deciphering microbiome signatures in chronic diseases for early diagnosis and modulation therapies) (Institutional-HR)
CENTRO-01-0145-FEDER-000012-N2323
Researcher
CNC.IBILI; Universidade de Coimbra
Funders: European Regional Development Fund; Comissão de Coordenação e Desenvolvimento Regional do Centro
2017 - 2020
The toxinogenic gut microbiome in sporadic Parkinson's Disease: a quest for "antiPDbiotics" (Co-PI)
Mantero Belard Prize 2016 - MB-40-2016
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Santa Casa da Misericórdia de Lisboa
2016 - 2016
The impairment of neuronal metabolism by gut microbiome effectors
FMUC-BST-2016-221
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Faculdade de Medicina, Universidade de Coimbra & Banco Santander
2016 - 2018
MICROCARE - Microbiome of diabetic ulcers: early diagnosis, prognosis and therapy (Co-PI)
FIS-2015-01_DIA_20150630-144
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Infarmed - Fundo para a Investigação em Saúde
2015 - 2017
Combination therapy synergistically accelerates diabetic wound closure
EFSD/Novartis Programme 2015
Other
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: European Association for the Study of Diabetes
2014 - 2015
Produção e comercialização global de compostos microbianos essenciais para investigação
InovC 2014
Principal investigator
Universidade de Coimbra
Funders: European Regional Development Fund
2013 - 2015
Biosynthesis of rare methylmannose polysaccharides in nontuberculous mycobacteria (PI)
PTDC/BIA-MIC/2779/2012
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2013 - 2015
Ambiguity and virulence in a human pathogen
PTDC/BBB-BEP/0695/2012
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular; Universidade do Porto Instituto de Biologia Molecular e Celular
Funders: Fundação para a Ciência e a Tecnologia
2012 - 2014
Unravelling the early steps in the biosynthesis of the mycobacterial MGLP (PI)
Grant 120123
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Mizutani Foundation for Glycoscience
2011 - 2014
Pathway for the synthesis of the mycobacterial MGLP. Biochemical and structural characterization of the key enzymes (PI)
PTDC/BIA-PRO/110523/2009
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2011 - 2013
The enigmatic mycobacterial maltokinase (PI)
PTDC/BIA-BCM/112459/2009
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2009 - 2010
Characterization and evolution of a rare glycosyltransferase from the anti-tumor producing bacteria of the genus Actinosynnema (PI)
Acordo cultural 2010 Eslováquia 124626903612592
Principal investigator
Universidade de Coimbra Centro de Neurociências e Biologia Celular
2008 - 2010
Cloning, expression and regulation of genes for the synthesis of compatible solutes in Thermus thermophilus
Acção Nº E-9/08
Researcher
Universidade de Coimbra
Funders: Conselho de Reitores das Universidades Portuguesas, Portugal
2005 - 2008
Compatible solutes from extremophiles: screening, biosynthesis and heterologous production
POCI/V.5/A0005/2005
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2005 - 2006
O Mundo dos Micróbios - Colecção Portuguesa de Bactérias (CPB) e Laboratório Acreditado de Controlo Microbiológico
REEQ/851/BIO/2005
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2005 - 2008
Nature´s shields to environmental stress. Biosynthesis of compatible solutes in extremely radiation-resistant Rubrobacter spp.
POCI/BIA-MIC/56511/2004
Researcher
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: Fundação para a Ciência e a Tecnologia
2004 - 2006
HOTSOLUTES - New applications for compatible solutes from Extremophiles
COOP-CT-2003-508644
Post-doc Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular
Funders: European Commission
2001 - 2004
New compatible solutes from thermophiles and hyperthermophiles: screening, identification and physiological role
POCTI/BIO/42331/2001
PhD Student Fellow
IMAR - Centro Interdisciplinar de Coimbra
Funders: Fundação para a Ciência e a Tecnologia
2001 - 2004
Towards the Utilization of Cell-Reactors for the Production of Mannosylglycerate, an Enzyme Stabilizer from Hyperthermophiles
POCTI/BIO/35715/1999
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Funders: Fundação para a Ciência e a Tecnologia
2001 - 2003
HYPERSOLUTES - Exploiting new solutes from hyperthermophiles for the preservation of biomaterials: cell factories for production of hypersolutes
QLK3-CT-2000-00640
PhD Student Fellow
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica
Funders: European Commission
5 31 out of 31 projects
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