Paulo Matafome

Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes <i>Mellitus</i>

Sónia Rocha; Andreia Marreiros Amaro; Marcos Divino Ferreira-Junior; Carina Proença; Artur M. S. Silva; Costa, V M; Sara Oliveira; et al, Pharmaceutics. 2024. https://www.mdpi.com/1999-4923/16/2/261 . 10.3390/pharmaceutics16020261 . Pharmaceutics

Clinical and molecular profiling of human visceral adipose tissue reveals impairment of vascular architecture and remodeling as an early hallmark of dysfunction

Daniela Rosendo-Silva; Pedro Bastos Gomes; Tiago Rodrigues; Sofia Viana; André Nogueira da Costa; Philipp E. Scherer; Flávio Reis; et al, Metabolism. 2024. http://dx.doi.org/10.1016/j.metabol.2024.155788 . 10.1016/j.metabol.2024.155788 . Metabolism

The Bidirectional Relationship of NPY and Mitochondria in Energy Balance Regulation

Diana Sousa; Eduardo Lopes; Daniela Rosendo-Silva; Paulo Matafome, Biomedicines. 2023. https://doi.org/10.3390/biomedicines11020446 . 10.3390/biomedicines11020446 . Biomedicines

Exposure to Obesogenic Environments during Perinatal Development Modulates Offspring Energy Balance Pathways in Adipose Tissue and Liver of Rodent Models

Diana Sousa; Mariana Rocha; Andreia Marreiros Amaro; Marcos Divino Ferreira-Junior; Keilah Valéria Naves Cavalcante; Tamaeh Monteiro-Alfredo; Tamaeh Monteiro Alfredo; Cátia Barra; et al, Nutrients. 2023. https://www.mdpi.com/2072-6643/15/5/1281 . 10.3390/nu15051281 . Nutrients

Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice

Sousa, Adelaide; Azevedo, Rui; Costa, Vera Marisa; Oliveira, Sara; Preguiça, Inês; Viana, Sofia; Reis, Flávio; et al, Archives of Toxicology. 2643 - 2657. 10. 97. 2023. http://dx.doi.org/10.1007/s00204-023-03558-5 . 10.1007/s00204-023-03558-5 . Archives of Toxicology

Functional imaging and neurochemistry identify in vivo neuroprotection mechanisms counteracting excitotoxicity and neurovascular changes in the hippocampus and visual cortex of obese and type 2 diabetic animal models

Beatriz Caramelo; Tamaeh Monteiro-Alfredo; João Martins; José Sereno; João Castelhano; Bruno Manadas; Miguel Castelo-Branco; et al, Journal of Neurochemistry. 2023. https://doi.org/10.1111/jnc.15825 . 10.1111/jnc.15825 . Journal of Neurochemistry

Postnatal Overfeeding in Rodents Induces a Neurodevelopment Delay and Anxious-like Behaviour Accompanied by Sex- and Brain-Region-Specific Synaptic and Metabolic Changes

Amaro, Andreia; Sousa, Diana; Sá-Rocha, Mariana; Ferreira-Junior, Marcos Divino; Rosendo-Silva, Daniela; Saavedra, Lucas Paulo Jacinto; Barra, Cátia; et al, Nutrients. 16. 15. 2023. http://dx.doi.org/10.3390/nu15163581 . 10.3390/nu15163581 . Nutrients

New Therapeutic Strategies for Obesity and Its Metabolic Sequelae: Brazilian Cerrado as a Unique Biome

Tamaeh Monteiro-Alfredo; Maria Lígia Rodrigues Macedo; Kely de Picoli Souza; Paulo Matafome, International Journal of Molecular Sciences. 2023. https://doi.org/10.3390/ijms242115588 . 10.3390/ijms242115588 . International Journal of Molecular Sciences

Sex-specificities in offspring neurodevelopment and behaviour upon maternal glycation: Putative underlying neurometabolic and synaptic changes.

Amaro A; Sousa D; Sá-Rocha M; Ferreira-Júnior MD; Barra C; Monteiro T; Mathias P; et al, Life sciences. 2023. http://europepmc.org/abstract/med/36948389 . 10.1016/j.lfs.2023.121597 . Life sciences

Nutritional Modulation of Dietary Sugars as a Strategy to Improve Insulin Resistance and Energy Balance in Diabetes

Paulo Matafome, Diabetology. 2023. https://doi.org/10.3390/diabetology4020018 . 10.3390/diabetology4020018 . Diabetology

Are gut dysbiosis, barrier disruption, and endotoxemia related to adipose tissue dysfunction in metabolic disorders? Overview of the mechanisms involved

Daniela Rosendo-Silva; Sofia Viana; Eugénia Carvalho; Flávio Reis; Paulo Matafome, Internal and Emergency Medicine. 2023. https://doi.org/10.1007/s11739-023-03262-3 . 10.1007/s11739-023-03262-3 . Internal and Emergency Medicine

Circulating Dopamine Is Regulated by Dietary Glucose and Controls Glucagon-like 1 Peptide Action in White Adipose Tissue

Tavares, Gabriela; Rosendo-Silva, Daniela; Simoes, Flavia; Eickhoff, Hans; Marques, Daniela; Sacramento, Joana F.; Capucho, Adriana M.; et al, International Journal of Molecular Sciences. 2023. https://publons.com/wos-op/publon/55340043/ . 10.3390/IJMS24032464 . International Journal of Molecular Sciences

<i>Acrocomia aculeata</i> associated with doxorubicin: cardioprotection and anticancer activity

Monteiro-Alfredo, Tamaeh; dos Santos, Jessica Maurino; Antunes, Katia Avila; Cunha, Janielle; Baldivia, Debora da Silva; Pires, Ana Salome; Marques, Ines; et al, Frontiers in Pharmacology. 2023. https://publons.com/wos-op/publon/61325685/ . 10.3389/FPHAR.2023.1223933 . Frontiers in Pharmacology

Early postnatal exposure of rat pups to methylglyoxal induces oxidative stress, inflammation and dysmetabolism at adulthood.

Flávio A. Francisco , Journal of developmental origins of health and disease. 2022. https://doi.org/10.1017/S204017442100074X . 10.1017/s204017442100074x . Journal of developmental origins of health and disease

Gut Metabolism of Sugars: Formation of Glycotoxins and Their Intestinal Absorption

Tamaeh Monteiro-Alfredo; Paulo Matafome, Diabetology. 2022. https://doi.org/10.3390/diabetology3040045 . 10.3390/diabetology3040045 . Diabetology

Updated Information of the Effects of (Poly)phenols against Type-2 Diabetes Mellitus in Humans: Reinforcing the Recommendations for Future Research

Regina Menezes; Paulo Matafome; Marisa Freitas; María-Teresa García-Conesa, Nutrients. 2022. https://doi.org/10.3390/nu14173563 . 10.3390/nu14173563 . Nutrients

Improvement of Glycaemia and Endothelial Function by a New Low-Dose Curcuminoid in an Animal Model of Type 2 Diabetes

Sara Oliveira; Tamaeh Monteiro-Alfredo; Rita Henriques; Carlos Fontes Ribeiro; Raquel Seiça; Cruz MT; Célia Cabral; et al, International Journal of Molecular Sciences. 2022. https://www.mdpi.com/1422-0067/23/10/5652 . 10.3390/ijms23105652 . International Journal of Molecular Sciences

Benefits, mechanisms, and risks of intermittent fasting in metabolic syndrome and type 2 diabetes

Lisandra Joaquim; Ana Faria; Helena Loureiro; Paulo Matafome, Journal of Physiology and Biochemistry. 2022. https://doi.org/10.1007/s13105-021-00839-4 . 10.1007/s13105-021-00839-4 . Journal of Physiology and Biochemistry

Programming of future generations during breastfeeding: The intricate relation between metabolic and neurodevelopment disorders

Amaro, Andreia; Baptista, Filipa I.; Matafome, Paulo, Life Sciences. 2022. http://dx.doi.org/10.1016/j.lfs.2022.120526 . 10.1016/j.lfs.2022.120526 . published Life Sciences

Sex-specific changes in peripheral metabolism in a model of chronic anxiety induced by prenatal stress

Ferreira, A.S.; Galvão, S.; Gaspar, R.; Rodrigues-Neves, A.C.; Ambrósio, A.F.; Matafome, P.; Gomes, C.A.; Baptista, F.I., European Journal of Clinical Investigation. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85108261049&partnerID=MN8TOARS . 10.1111/eci.13639 . European Journal of Clinical Investigation

Hypoglycaemic and Antioxidant Properties of <i>Acrocomia aculeata</i> (Jacq.) Lodd Ex Mart. Extract Are Associated with Better Vascular Function of Type 2 Diabetic Rats

Tamaeh Monteiro-Alfredo; Tamaeh Monteiro Alfredo; Sara Oliveira; Andreia Amaro; Daniela Rosendo-Silva; Katia Antunes; Pires AS; Ricardo Teixo; et al, Nutrients. 2021. https://www.mdpi.com/2072-6643/13/8/2856 . 10.3390/nu13082856 . Nutrients

Distinct Impact of Natural Sugars from Fruit Juices and Added Sugars on Caloric Intake, Body Weight, Glycaemia, Oxidative Stress and Glycation in Diabetic Rats

Tamaeh Monteiro-Alfredo; Beatriz Caramelo; Daniela Arbeláez; Andreia Amaro; Cátia Barra; Daniela Silva; Sara Oliveira; Raquel Seiça; Paulo Matafome, Nutrients. 2956 - 2956. 9. 13. 2021. https://doi.org/10.3390/nu13092956 . 10.3390/nu13092956 . Nutrients

Chronic Intermittent Hypoxia Induces Early-Stage Metabolic Dysfunction Independently of Adipose Tissue Deregulation

Fátima O. Martins; Joana F. Sacramento; Elena Olea; Bernardete F. Melo; Jesus Prieto-Lloret; Ana Obeso; Asuncion Rocher; et al, Antioxidants. 1233 - 1233. 8. 10. 2021. https://doi.org/10.3390/antiox10081233 . 10.3390/antiox10081233 . Antioxidants

Impairment of the angiogenic process may contribute to lower success rate of root canal treatments in diabetes mellitus

Martinho, J.P.; Coelho, A.; Oliveiros, B.; Pires, S.; Abrantes, A.M.; Paulo, S.; Carvalho, A.C.; et al, International Endodontic Journal. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85109415325&partnerID=MN8TOARS . 10.1111/iej.13572 . International Endodontic Journal

Plasma activated media and direct exposition can selectively ablate retinoblastoma cells

Silva-Teixeira, R.; Laranjo, M.; Lopes, B.; Almeida-Ferreira, C.; Gonçalves, A.C.; Rodrigues, T.; Matafome, P.; et al, Free Radical Biology and Medicine. 302 - 313. 171. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85106496334&partnerID=MN8TOARS . 10.1016/j.freeradbiomed.2021.05.027 . Free Radical Biology and Medicine

Early AGEing and metabolic diseases: Is perinatal exposure to glycotoxins programming for adult-life metabolic syndrome?

Francisco, F.A.; Saavedra, L.P.J.; Junior, M.D.F.; Barra, C.; Matafome, P.; Mathias, P.C.F.; Gomes, R.M., Nutrition Reviews. 13 - 24. 1. 79. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85098460824&partnerID=MN8TOARS . 10.1093/nutrit/nuaa074 . Nutrition Reviews

COVID-19 During Development: A Matter of Concern

Saavedra, L.P.J.; Prates, K.V.; Gonçalves, G.D.; Piovan, S.; Matafome, P.; Mathias, P.C.D.F., Frontiers in Cell and Developmental Biology. 9. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85104635646&partnerID=MN8TOARS . 10.3389/fcell.2021.659032 . Frontiers in Cell and Developmental Biology

Oxymestane, a cytostatic steroid derivative of exemestane with greater antitumor activity in non-estrogen-dependent cell lines

Ana S. Pires; Carla L. Varela; Inês A. Marques; Ana M. Abrantes; Cristina Gonçalves; Tiago Rodrigues; Paulo Matafome; et al, The Journal of Steroid Biochemistry and Molecular Biology. 105950 - 105950. 212. 2021. https://doi.org/10.1016/j.jsbmb.2021.105950 . 10.1016/j.jsbmb.2021.105950 . The Journal of Steroid Biochemistry and Molecular Biology

Dopamine D2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes

Tavares, G.; Marques, D.; Barra, C.; Rosendo-Silva, D.; Costa, A.; Rodrigues, T.; Gasparini, P.; et al, Molecular Metabolism. 51. 2021. http://www.scopus.com/inward/record.url?eid=2-s2.0-85106861458&partnerID=MN8TOARS . 10.1016/j.molmet.2021.101241 . Molecular Metabolism

Peripheral Dopamine Directly Acts on Insulin-Sensitive Tissues to Regulate Insulin Signaling and Metabolic Function

Tavares, Gabriela; Martins, Fatima. O.; Melo, Bernardete. F.; Matafome, Paulo; Conde, Silvia. V., Frontiers in Pharmacology. 12. 2021. http://dx.doi.org/10.3389/fphar.2021.713418 . 10.3389/fphar.2021.713418 . Frontiers in Pharmacology

Mice with Type 2 Diabetes Present Significant Alterations in Their Tissue Biomechanical Properties and Histological Features

Tânia B. Cruz; Filomena A. Carvalho; Paulo N. Matafome; Raquel A. Soares; Nuno C. Santos; Rui D. Travasso; Maria J. Oliveira, Biomedicines. 2021. https://doi.org/10.3390/biomedicines10010057 . 10.3390/biomedicines10010057 . Biomedicines

Kinetics of radium-223 and its effects on survival, proliferation and DNA damage in lymph-node and bone metastatic prostate cancer cell lines

Inês A. Marques; Ana M. Abrantes; Ana S. Pires; Ana R. Neves; Francisco J. Caramelo; Tiago Rodrigues; Paulo Matafome; et al, International Journal of Radiation Biology. 1 - 16. 2021. https://doi.org/10.1080/09553002.2021.1906462 . 10.1080/09553002.2021.1906462 . International Journal of Radiation Biology

Gut–adipose tissue crosstalk: A bridge to novel therapeutic targets in metabolic syndrome?

Daniela Rosendo-Silva; Paulo Matafome, Obesity Reviews. 2. 22. 2021. https://doi.org/10.1111/obr.13130 . 10.1111/obr.13130 . Obesity Reviews

Alterations of the ghrelin/NPY adipose tissue system as a therapeutic target in type 2 diabetes

Rosendo-Silva, Daniela; Eickhoff, H; Gomes, P.; Viana, S.; AS Pires; Abrantes, Ana Margarida; Reis, F.; et al, European Journal of Clinical Investigation. S1. 51. 2021. http://dx.doi.org/10.1111/eci.13564 . 10.1111/eci.13564 . European Journal of Clinical Investigation

Lactation as a programming window for metabolic syndrome

Catalina Picó; Flávio Reis; Conceição Egas; Paulo Mathias; Paulo Matafome, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13482 . 10.1111/eci.13482 . European Journal of Clinical Investigation

Dietary Imbalance between Natural and Added Nutrient Sources Is Associated with Higher Fat Mass in Young Non-Obese Individuals

Margarida Sá-Marta; Mariana Marques; João Figueiredo; Ana Faria; Helena Loureiro; Sónia Fialho; Paulo Matafome, Diabetology. 2021. https://doi.org/10.3390/diabetology2020008 . 10.3390/diabetology2020008 . Diabetology

Metabolic Disease Programming: From Mitochondria to Epigenetics, Glucocorticoid Signalling and Beyond

Luís F. Grilo; Carolina Tocantins; Mariana S. Diniz; Rodrigo Mello Gomes; Paulo J. Oliveira; Paulo Matafome; Susana P. Pereira, European Journal of Clinical Investigation. 2021. https://doi.org/10.1111/eci.13625 . 10.1111/eci.13625 . European Journal of Clinical Investigation

A rat model of enhanced glycation mimics cardiac phenotypic components of human type 2 diabetes : A translational study using MRI

Castelhano, J.; Ribeiro, B.; Sanches, M.; Graça, B.; Saraiva, J.; Oliveiros, B.; Neves, C.; et al, Journal of Diabetes and its Complications. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85080056491&partnerID=MN8TOARS . 10.1016/j.jdiacomp.2020.107554 . Journal of Diabetes and its Complications

Curcumin derivatives for Type 2 Diabetes management and prevention of complications

Sara Oliveira; Tamaeh Monteiro-Alfredo; Sónia Silva; Paulo Matafome, Archives of Pharmacal Research. 2020. https://doi.org/10.1007/s12272-020-01240-3 . 10.1007/s12272-020-01240-3 . Archives of Pharmacal Research

Acrocomia aculeata (Jacq.) Lodd. ex Mart. Leaves Increase SIRT1 Levels and Improve Stress Resistance

Tamaeh Monteiro-Alfredo; Paulo Matafome; Bianca Pancoti Iacia; Kátia Ávila Antunes; Jéssica Maurino dos Santos; Janielle da Silva Melo da Cunha; Sara Oliveira; et al, Oxidative Medicine and Cellular Longevity. 2020. https://doi.org/10.1155/2020/5238650 . 10.1155/2020/5238650 . Oxidative Medicine and Cellular Longevity

Epicardial adipose tissue (dys)function: A new player in heart disease?,(Dis)função do tecido adiposo epicárdico: um novo interveniente nas doenças cardíacas?

Matafome, P., Revista Portuguesa de Cardiologia. 635 - 637. 11. 39. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85095796133&partnerID=MN8TOARS . 10.1016/j.repc.2020.10.001 . Revista Portuguesa de Cardiologia

GLP-1 improves adipose tissue glyoxalase activity and capillarization improving insulin sensitivity in type 2 diabetes

Rodrigues, T.; Borges, P.; Mar, L.; Marques, D.; Albano, M.; Eickhoff, H.; Carrêlo, C.; et al, Pharmacological Research. 161. 2020. http://www.scopus.com/inward/record.url?eid=2-s2.0-85092033726&partnerID=MN8TOARS . 10.1016/j.phrs.2020.105198 . Pharmacological Research

A2 Adenosine Receptors Mediate Whole-Body Insulin Sensitivity in a Prediabetes Animal Model: Primary Effects on Skeletal Muscle

Matafome, Paulo, Frontiers in Endocrinology. 2020. http://dx.doi.org/10.3389/fendo.2020.00262 . 10.3389/fendo.2020.00262 . Frontiers in Endocrinology

Surface-PASylation of ferritin to form stealth nanovehicles enhances <i>in vivo</i> therapeutic performance of encapsulated ellipticine

Tesarova, Barbora; Dostalova, Simona; Smidova, Veronika; Goliasova, Zita; Skubalova, Zuzana; Michalkova, Hana; Hynek, David; et al, Applied Materials Today. 18. 2020. https://publons.com/wos-op/publon/28308249/ . 10.1016/J.APMT.2019.100501 . Applied Materials Today

Another Player in the Field: Involvement of Glycotoxins and Glycosative Stress in Insulin Secretion and Resistance

Paulo Matafome, Diabetology. 2020. https://www.mdpi.com/2673-4540/1/1/4 . 10.3390/diabetology1010004 . Diabetology

Association between adipokines and biomarkers of Alzheimer's disease: A cross-sectional study

Letra, L.; Matafome, P.; Rodrigues, T.; Duro, D.; Lemos, R.; Baldeiras, I.; Patrcio, M.; et al, Journal of Alzheimer's Disease. 725 - 735. 2. 67. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85060571460&partnerID=MN8TOARS . 10.3233/JAD-180669 . Journal of Alzheimer's Disease

Evaluating the Impact of Different Hypercaloric Diets on Weight Gain, Insulin Resistance, Glucose Intolerance, and its Comorbidities in Rats

Melo, B.F.; Sacramento, J.F.; Ribeiro, M.J.; Prego, C.S.; Correia, M.C.; Coelho, J.C.; Cunha-Guimaraes, J.P.; et al, Nutrients. 6. 11. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85067310280&partnerID=MN8TOARS . 10.3390/nu11061197 . Nutrients

Adiponectin and sporadic Alzheimer's disease: Clinical and molecular links

Letra, L.; Rodrigues, T.; Matafome, P.; Santana, I.; Seiça, R., Frontiers in Neuroendocrinology. 1 - 11. 52. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031740092&partnerID=MN8TOARS . 10.1016/j.yfrne.2017.10.002 . Frontiers in Neuroendocrinology

Dietary glycotoxins impair hepatic lipidemic profile in diet-induced obese rats causing hepatic oxidative stress and insulin resistance

Neves, C.; Rodrigues, T.; Sereno, J.; Simões, C.; Castelhano, J.; Gonçalves, J.; Bento, G.; et al, Oxidative Medicine and Cellular Longevity. 2019. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85070523456&partnerID=MN8TOARS . 10.1155/2019/6362910 . Oxidative Medicine and Cellular Longevity

Effect of Sleeve Gastrectomy on Angiogenesis and Adipose Tissue Health in an Obese Animal Model of Type 2 Diabetes

Eickhoff, H.; Rodrigues, T.; Neves, I.; Marques, D.; Ribeiro, D.; Costa, S.; Seiça, R.; Matafome, P., Obesity Surgery. 2019. http://www.scopus.com/inward/record.url?eid=2-s2.0-85066888512&partnerID=MN8TOARS . 10.1007/s11695-019-03935-z . Obesity Surgery

Using Resistin, glucose, age and BMI to predict the presence of breast cancer

Patrício, M.; Pereira, J.; Crisóstomo, J.; Matafome, P.; Gomes, M.; Seiça, R.; Caramelo, F., BMC Cancer. 1. 18. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042511022&partnerID=MN8TOARS . 10.1186/s12885-017-3877-1 . BMC Cancer

Tissular growth factors profile after teduglutide administration on an animal model of intestinal anastomosis,Perfil tisular de factores de crecimiento postadministración de teduglutida en un modelo animal de anastomosis intestinal

da Costa, B.P.; Gonçalves, A.C.; Abrantes, A.M.; Alves, R.; Matafome, P.; Sarmento-Ribeiro, R.S.A.B.; Botelho, M.F.; Castro-Sousa, F., Nutricion Hospitalaria. 185 - 193. 1. 35. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044216245&partnerID=MN8TOARS . 10.20960/nh.1326 . Nutricion Hospitalaria

Intestinal Epithelial Stem Cells: Distinct Behavior After Surgical Injury and Teduglutide Administration

Costa, B.P.; Gonçalves, A.C.; Abrantes, A.M.; Alves, R.; Matafome, P.; Seiça, R.; Sarmento-Ribeiro, A.B.; Botelho, M.F.; Castro-Sousa, F., Journal of Investigative Surgery. 243 - 252. 3. 31. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85016505953&partnerID=MN8TOARS . 10.1080/08941939.2017.1294217 . Journal of Investigative Surgery

High-fat diet induces a neurometabolic state characterized by changes in glutamate and N-acetylaspartate pools associated with early glucose intolerance: An in vivo multimodal MRI study

Ribeiro, M.; Castelhano, J.; Petrella, L.I.; Sereno, J.; Rodrigues, T.; Neves, C.; Letra, L.; et al, Journal of Magnetic Resonance Imaging. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041034539&partnerID=MN8TOARS . 10.1002/jmri.25942 . Journal of Magnetic Resonance Imaging

MicroRNA-424(322) as a new marker of disease progression in pulmonary arterial hypertension and its role in right ventricular hypertrophy by targeting SMURF1

Baptista, R.; Marques, C.; Catarino, S.; Enguita, F.J.; Costa, M.C.; Matafome, P.; Zuzarte, M.; et al, Cardiovascular Research. 53 - 64. 1. 114. 2018. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040537877&partnerID=MN8TOARS . 10.1093/cvr/cvx187 . Cardiovascular Research

Sleeve gastrectomy improves endothelial dysfunction in type 2 diabetic rats

Sena, Cristina M.; Eickhoff, Hans; Ribeiro, Diana; Matafome, Paulo; Seiça, Raquel, Free Radical Biology and Medicine. 120. 2018. http://dx.doi.org/10.1016/j.freeradbiomed.2018.04.525 . 10.1016/j.freeradbiomed.2018.04.525 . published Free Radical Biology and Medicine

Targeting adipose tissue glyoxalase system with GLP-1 to improve capillarisation and insulin sensitivity

Matafome, P.; Rodrigues, T.; Borges, P.; Carrelo, C.; Mar, L.; Eickhoff, H.; Almeida, B.; et al, Diabetologia. 61 (Sup.1). 2018. https://publons.com/wos-op/publon/39159850/ . Diabetologia

Functional abolition of carotid body activity restores insulin action and glucose homeostasis in rats: key roles for visceral adipose tissue and the liver

Sacramento, J.F.; Ribeiro, M.J.; Rodrigues, T.; Olea, E.; Melo, B.F.; Guarino, M.P.; Fonseca-Pinto, R.; et al, Diabetologia. 158 - 168. 1. 60. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991325548&partnerID=MN8TOARS . 10.1007/s00125-016-4133-y . Diabetologia

Effects of teduglutide on histological parameters of intestinal anastomotic healing

Costa, B.P.; Cipriano, M.A.; Gonçalves, A.C.; Abrantes, A.M.; Matafome, P.; Seiça, R.; Sarmento-Ribeiro, A.B.; Botelho, M.F.; Castro-Sousa, F., European Surgery - Acta Chirurgica Austriaca. 218 - 227. 5. 49. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018470904&partnerID=MN8TOARS . 10.1007/s10353-017-0478-9 . European Surgery - Acta Chirurgica Austriaca

Teduglutide effects on gene regulation of fibrogenesis on an animal model of intestinal anastomosis

Costa, B.P.; Gonçalves, A.C.; Abrantes, A.M.; Matafome, P.; Seiça, R.; Sarmento-Ribeiro, A.B.; Botelho, M.F.; Castro-Sousa, F., Journal of Surgical Research. 87 - 98. 216. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019557502&partnerID=MN8TOARS . 10.1016/j.jss.2017.04.022 . Journal of Surgical Research

Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in rats

Da Costa, B.P.; Gonçalves, A.C.; Abrantes, A.M.; Matafome, P.; Seiça, R.; Sarmento-Ribeiro, A.B.; Botelho, M.F.; Castro-Sousa, F., Acta Cirurgica Brasileira. 648 - 661. 8. 32. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85029415807&partnerID=MN8TOARS . 10.1590/s0102-865020170080000007 . Acta Cirurgica Brasileira

Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance /692/163/2743/2037 /692/308/1426 /13/106 /59 /59/36 article

Rodrigues, T.; Matafome, P.; Sereno, J.; Almeida, J.; Castelhano, J.; Gamas, L.; Neves, C.; et al, Scientific Reports. 1. 7. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019208734&partnerID=MN8TOARS . 10.1038/s41598-017-01730-3 . Scientific Reports

Methylglyoxal in Metabolic Disorders: Facts, Myths, and Promises

Matafome, P.; Rodrigues, T.; Sena, C.; Seiça, R., Medicinal Research Reviews. 368 - 403. 2. 37. 2017. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987858663&partnerID=MN8TOARS . 10.1002/med.21410 . Medicinal Research Reviews

Hyperresistinemia and metabolic dysregulation: a risky crosstalk in obese breast cancer

Crisóstomo, J.; Matafome, P.; Santos-Silva, D.; Gomes, A.L.; Gomes, M.; Patrício, M.; Letra, L.; et al, Endocrine. 433 - 442. 2. 53. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84958751473&partnerID=MN8TOARS . 10.1007/s12020-016-0893-x . Endocrine

Insulin resistance is associated with tissue-specific regulation of HIF-1a and HIF-2a during mild chronic intermittent hypoxia

Sacramento, J.F.; Ribeiro, M.J.; Rodrigues, T.; Guarino, M.P.; Diogo, L.N.; Seiça, R.; Monteiro, E.C.; Matafome, P.; Conde, S.V., Respiratory Physiology and Neurobiology. 30 - 38. 228. 2016. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961279467&partnerID=MN8TOARS . 10.1016/j.resp.2016.03.007 . Respiratory Physiology and Neurobiology

Irisin and myonectin regulation in the insulin resistant muscle: Implications to adipose tissue: Muscle crosstalk

Gamas, L.; Matafome, P.; Seica, R., Journal of Diabetes Research. 2015. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929646308&partnerID=MN8TOARS . 10.1155/2015/359159 . Journal of Diabetes Research

Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

Martins-Marques, T.; Catarino, S.; Zuzarte, M.; Marques, C.; Matafome, P.; Pereira, P.; Girão, H., Biochemical Journal. 231 - 245. 2. 467. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84930798449&partnerID=MN8TOARS . 10.1042/BJ20141370 . Biochemical Journal

Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs

Martins-Marques, T.; Catarino, S.; Marques, C.; Matafome, P.; Ribeiro-Rodrigues, T.; Baptista, R.; Pereira, P.; Girão, H., Biochimie. 196 - 201. 112. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964307751&partnerID=MN8TOARS . 10.1016/j.biochi.2015.02.020 . Biochimie

Glycation and Hypoxia: Two Key Factors for Adipose Tissue Dysfunction

Matafome, P.; Rodrigues, T.; Seiça, R., Current Medicinal Chemistry. 2417 - 2437. 20. 22. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938651322&partnerID=MN8TOARS . Current Medicinal Chemistry

Amelioration of Glycemic Control by Sleeve Gastrectomy and Gastric Bypass in a Lean Animal Model of Type 2 Diabetes: Restoration of Gut Hormone Profile

Eickhoff, H.; Louro, T.M.; Matafome, P.N.; Vasconcelos, F.; Seiça, R.M.; Castro e Sousa, F., Obesity Surgery. 7 - 18. 1. 25. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84939893973&partnerID=MN8TOARS . 10.1007/s11695-014-1309-8 . Obesity Surgery

The Force at the Tip - Modelling Tension and Proliferation in Sprouting Angiogenesis

Santos-Oliveira, P.; Correia, A.; Rodrigues, T.; Ribeiro-Rodrigues, T.M.; Matafome, P.; Rodríguez-Manzaneque, J.C.; Seiça, R.; Girão, H.; Travasso, R.D.M., PLoS Computational Biology. 8. 11. 2015. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940778593&partnerID=MN8TOARS . 10.1371/journal.pcbi.1004436 . PLoS Computational Biology

Glucagon secretion after metabolic surgery in diabetic rodents

Eickhoff, H.; Louro, T.; Matafome, P.; Seiça, R.; Castro e Sousa, F., Journal of Endocrinology. 255 - 265. 3. 223. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84911961407&partnerID=MN8TOARS . 10.1530/JOE-14-0445 . Journal of Endocrinology

Advanced glycation end products and diabetic nephropathy: A comparative study using diabetic and normal rats with methylglyoxal-induced glycation

Rodrigues, L.; Matafome, P.; Crisóstomo, J.; Santos-Silva, D.; Sena, C.; Pereira, P.; Seiça, R., Journal of Physiology and Biochemistry. 173 - 184. 1. 70. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896355519&partnerID=MN8TOARS . 10.1007/s13105-013-0291-2 . Journal of Physiology and Biochemistry

A vascular piece in the puzzle of adipose tissue dysfunction: Mechanisms and consequences

Rodrigues, T.; Matafome, P.; Seiça, R., Archives of Physiology and Biochemistry. 1 - 11. 1. 120. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893065442&partnerID=MN8TOARS . 10.3109/13813455.2013.838971 . Archives of Physiology and Biochemistry

Atorvastatin-mediated protection of the retina in a model of diabetes with hyperlipidemia

Fernandes, R.; Bento, C.F.; Matafome, P.; Sena, C.M.; Seiça, R.M.; Pereira, P., Canadian Journal of Physiology and Pharmacology. 1037 - 1043. 12. 92. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84912050638&partnerID=MN8TOARS . 10.1139/cjpp-2014-0212 . Canadian Journal of Physiology and Pharmacology

Long-term globular adiponectin administration improves adipose tissue dysmetabolism in high-fat diet-fed Wistar rats

Matafome, P.; Rodrigues, T.; Pereira, A.; Letra, L.; Azevedo, H.; Paixão, A.; Silvério, M.; et al, Archives of Physiology and Biochemistry. 147 - 157. 4. 120. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907529381&partnerID=MN8TOARS . 10.3109/13813455.2014.950590 . Archives of Physiology and Biochemistry

Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status

Cardoso, S.; Carvalho, C.; Marinho, R.; Simões, A.; Sena, C.M.; Matafome, P.; Santos, M.S.; Seiça, R.M.; Moreira, P.I., Journal of Bioenergetics and Biomembranes. 347 - 355. 5. 46. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919396245&partnerID=MN8TOARS . 10.1007/s10863-014-9551-2 . Journal of Bioenergetics and Biomembranes

Effects of atorvastatin and insulin in vascular dysfunction associated with type 2 diabetes

Sena, C.M.; Matafome, P.; Louro, T.; Nunes, E.; Seiça, R.M., Physiological Research. 189 - 197. 2. 63. 2014. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899916325&partnerID=MN8TOARS . Physiological Research

Methylglyoxal further impairs adipose tissue metabolism after partial decrease of blood supply

Rodrigues, T.; Matafome, P.; Seiça, R., Archives of Physiology and Biochemistry. 209 - 218. 5. 119. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887938844&partnerID=MN8TOARS . 10.3109/13813455.2013.812121 . Archives of Physiology and Biochemistry

Common mechanisms of dysfunctional adipose tissue and obesity-related cancers

Matafome, P.; Santos-Silva, D.; Sena, C.M.; Seiça, R., Diabetes/Metabolism Research and Reviews. 285 - 295. 4. 29. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877349617&partnerID=MN8TOARS . 10.1002/dmrr.2395 . Diabetes/Metabolism Research and Reviews

Methylglyoxal chronic administration promotes diabetes-like cardiac ischaemia disease in Wistar normal rats

Crisóstomo, J.; Matafome, P.; Santos-Silva, D.; Rodrigues, L.; Sena, C.M.; Pereira, P.; Seiça, R., Nutrition, Metabolism and Cardiovascular Diseases. 1223 - 1230. 12. 23. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888838277&partnerID=MN8TOARS . 10.1016/j.numecd.2013.01.005 . Nutrition, Metabolism and Cardiovascular Diseases

Pyridoxamine reverts methylglyoxal-induced impairment of survival pathways during heart ischemia

Almeida, F.; Santos-Silva, D.; Rodrigues, T.; Matafome, P.; Crisóstomo, J.; Sena, C.; Gonçalves, L.; Seiça, R., Cardiovascular Therapeutics. 6. 31. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888334166&partnerID=MN8TOARS . 10.1111/1755-5922.12039 . Cardiovascular Therapeutics

Reduction of methylglyoxal-induced glycation by pyridoxamine improves adipose tissue microvascular lesions

Rodrigues, T.; Matafome, P.; Santos-Silva, D.; Sena, C.; Seiça, R., Journal of Diabetes Research. 2013. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84879402930&partnerID=MN8TOARS . 10.1155/2013/690650 . Journal of Diabetes Research

Methylglyoxal, obesity, and diabetes

Matafome, P.; Sena, C.; Seiça, R., Endocrine. 472 - 484. 3. 43. 2013. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877873718&partnerID=MN8TOARS . 10.1007/s12020-012-9795-8 . Endocrine

Methylglyoxal promotes oxidative stress and endothelial dysfunction

Sena, C.M.; Matafome, P.; Crisóstomo, J.; Rodrigues, L.; Fernandes, R.; Pereira, P.; Seiça, R.M., Pharmacological Research. 497 - 506. 5. 65. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859788536&partnerID=MN8TOARS . 10.1016/j.phrs.2012.03.004 . Pharmacological Research

Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity

Matafome, P.; Santos-Silva, D.; Crisóstomo, J.; Rodrigues, T.; Rodrigues, L.; Sena, C.M.; Pereira, P.; Seiça, R., Archives of Physiology and Biochemistry. 58 - 68. 2. 118. 2012. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860751778&partnerID=MN8TOARS . 10.3109/13813455.2012.658065 . Archives of Physiology and Biochemistry

Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia

Matafome, P.; Louro, T.; Rodrigues, L.; Crisóstomo, J.; Nunes, E.; Amaral, C.; Monteiro, P.; Cipriano, A.; Seiça, R., Diabetes/Metabolism Research and Reviews. 54 - 62. 1. 27. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651103598&partnerID=MN8TOARS . 10.1002/dmrr.1157 . Diabetes/Metabolism Research and Reviews

Dietary restriction improves systemic and muscular oxidative stress in type 2 diabetic Goto-Kakizaki rats.

Rodrigues, L.; Crisóstomo, J.; Matafome, P.; Louro, T.; Nunes, E.; Seiça, R., Journal of physiology and biochemistry. 613 - 619. 4. 67. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-85027944303&partnerID=MN8TOARS . Journal of physiology and biochemistry

Metformin restores endothelial function in aorta of diabetic rats

Sena, C.M.; Matafome, P.; Louro, T.; Nunes, E.; Fernandes, R.; Seiça, R.M., British Journal of Pharmacology. 424 - 437. 2. 163. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-79954561745&partnerID=MN8TOARS . 10.1111/j.1476-5381.2011.01230.x . British Journal of Pharmacology

Insulin and metformin may prevent renal injury in young type 2 diabetic Goto-Kakizaki rats

Louro, T.M.; Matafome, P.N.; Nunes, E.C.; Xavier Da Cunha, F.; Seiça, R.M., European Journal of Pharmacology. 89 - 94. 1-3. 653. 2011. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651518054&partnerID=MN8TOARS . 10.1016/j.ejphar.2010.11.029 . European Journal of Pharmacology

Beneficial effects of dietary restriction in type 2 diabetic rats: The role of adipokines on inflammation and insulin resistance

Crisóstomo, J.; Rodrigues, L.; Matafome, P.; Amaral, C.; Nunes, E.; Louro, T.; Monteiro, P.; Seiça, R., British Journal of Nutrition. 76 - 82. 1. 104. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954668427&partnerID=MN8TOARS . 10.1017/S0007114510000164 . British Journal of Nutrition

Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction

Bento, C.F.; Fernandes, R.; Matafome, P.; Sena, C.; Seia, R.; Pereira, P., Experimental Physiology. 955 - 970. 9. 95. 2010. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955835661&partnerID=MN8TOARS . 10.1113/expphysiol.2010.053561 . Experimental Physiology

Food deprivation promotes oxidative imbalance in rat brain

Santos, R.X.; Cardoso, S.; Silva, S.; Correia, S.; Carvalho, C.; Crisóstomo, J.; Rodrigues, L.; et al, Journal of Food Science. 1. 74. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-58649112769&partnerID=MN8TOARS . 10.1111/j.1750-3841.2008.00982.x . Journal of Food Science

Antioxidant and vascular effects of gliclazide in type 2 diabetic rats fed high-fat diet

Sena, C.M.; Louro, T.; Matafome, P.; Nunes, E.; Monteiro, P.; Seiça, R., Physiological Research. 203 - 209. 2. 58. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-66349113765&partnerID=MN8TOARS . Physiological Research

A role for atorvastatin and insulin combination in protecting from liver injury in a model of type 2 diabetes with hyperlipidemia

Matafome, P.; Nunes, E.; Louro, T.; Amaral, C.; Crisóstomo, J.; Rodrigues, L.; Moedas, A.R.; et al, Naunyn-Schmiedeberg's Archives of Pharmacology. 241 - 251. 3. 379. 2009. http://www.scopus.com/inward/record.url?eid=2-s2.0-59449088781&partnerID=MN8TOARS . 10.1007/s00210-008-0363-y . Naunyn-Schmiedeberg's Archives of Pharmacology

Therapeutic association of atorvastatin and insulin in cardiac ischemia: Study in a model of type 2 diabetes with hyperlipidemia

Matafome, P.; Monteiro, P.; Nunes, E.; Louro, T.; Amaral, C.; Moedas, A.R.; Gonçalves, L.; Providência, L.; Seiça, R., Pharmacological Research. 208 - 214. 3-4. 58. 2008. http://www.scopus.com/inward/record.url?eid=2-s2.0-54349104633&partnerID=MN8TOARS . 10.1016/j.phrs.2008.07.005 . Pharmacological Research

Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets

Nunes, E.; Peixoto, F.; Louro, T.; Sena, C.M.; Santos, M.S.; Matafome, P.; Moreira, P.I.; Seiça, R., Acta Diabetologica. 121 - 130. 3. 44. 2007. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548177719&partnerID=MN8TOARS . 10.1007/s00592-007-0252-8 . Acta Diabetologica