Laetitia da Silva Gaspar

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Researcher

Affiliation

1: CNC - Centre for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; 2: CIBB - Centre for Innovation in Biomedicine and Biotechnology, University of Coimbra, Portugal; 3: IIIUC - Institute for Interdisciplinary Research, University of Coimbra, Coimbra, Portugal.

Publications

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Information about journal articles, updated at 19-05-2024, from platform CIÊNCIAVITAE.

Murine Pro-Inflammatory Responses to Acute and Sustained Intermittent Hypoxia: Implications for Obstructive Sleep Apnea Research

Bala S. C. Koritala; Laetitia S. Gaspar; Shweta S. Bhadri; Kyla S. Massie; Yin Yeng Lee; Jiffin Paulose; David F. Smith, The Laryngoscope. 2024. https://doi.org/10.1002/lary.30915 . 10.1002/lary.30915 . The Laryngoscope

A standardised protocol for blood and cerebrospinal fluid collection and processing for biomarker research in ataxia

Santana, Magda M.; Gaspar, Laetitia S.; Pinto, Maria M.; Silva, Patrick; Adão, Diana; Pereira, Dina; Ribeiro, Joana Afonso; et al, Neuropathology and Applied Neurobiology. 2. 49. 2023. http://dx.doi.org/10.1111/nan.12892 . 10.1111/nan.12892 . published Neuropathology and Applied Neurobiology

Obstructive sleep apnea in a mouse model is associated with tissue-specific transcriptomic changes in circadian rhythmicity and mean 24-hour gene expression

Koritala, Bala S. C.; Lee, Yin Yeng; Gaspar, Laetitia S.; Bhadri, Shweta S.; Su, Wen; Wu, Gang; Francey, Lauren J.; et al, PLOS Biology. 5. 21. 2023. http://dx.doi.org/10.1371/journal.pbio.3002139 . 10.1371/journal.pbio.3002139 . published PLOS Biology

Peripheral biomarkers to diagnose obstructive sleep apnea in adults: A systematic review and meta-analysis

Gaspar, Laetitia S.; Santos-Carvalho, Ana; Santos, Bárbara; Carvalhas-Almeida, Catarina; Barros-Viegas, Ana Teresa; Oliveiros, Bárbara; Donato, Helena; et al, Sleep Medicine Reviews. 64. 2022. http://dx.doi.org/10.1016/j.smrv.2022.101659 . 10.1016/j.smrv.2022.101659 . published Sleep Medicine Reviews

Intermittent Hypoxia Alters the Circadian Expression of Clock Genes in Mouse Brain and Liver

Koritala, Bala S. C.; Lee, Yin Yeng; Bhadri, Shweta S.; Gaspar, Laetitia S.; Stanforth, Corinne; Wu, Gang; Ruben, Marc D.; Francey, Lauren J.; Smith, David F., Genes. 10. 12. 2021. http://dx.doi.org/10.3390/genes12101627 . 10.3390/genes12101627 . published Genes

Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea

Gaspar, Laetitia S.; Hesse, Janina; Yalçin, Müge; Santos, Bárbara; Carvalhas-Almeida, Catarina; Ferreira, Mafalda; Moita, Joaquim; et al, EBioMedicine. 65. 2021. http://dx.doi.org/10.1016/j.ebiom.2021.103248 . 10.1016/j.ebiom.2021.103248 . published EBioMedicine

Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?

Gaspar, Laetitia S.; Sousa, Cátia; Álvaro, Ana Rita; Cavadas, Cláudia; Mendes, Alexandrina Ferreira, Pharmacological Research. 164. 2021. http://dx.doi.org/10.1016/j.phrs.2020.105369 . 10.1016/j.phrs.2020.105369 . published Pharmacological Research

The Superpowers of Our Sleep

Gaspar, Laetitia S.; Santos, Bárbara; Barros-Viegas, Ana Teresa; Cardoso, João; Varela Amaral, Sara; Carvalhas-Almeida, Catarina; Santos-Carvalho, Ana; Cavadas, Cláudia; Álvaro, Ana Rita, Frontiers for Young Minds. 8. 2020. http://dx.doi.org/10.3389/frym.2020.540052 . 10.3389/frym.2020.540052 . published Frontiers for Young Minds

Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research

Gaspar, Laetitia S.; Santana, Magda M.; Henriques, Carina; Pinto, Maria M.; Ribeiro-Rodrigues, Teresa M.; Girão, Henrique; Nobre, Rui Jorge; Pereira de Almeida, Luís, Molecular Therapy - Methods & Clinical Development. 723 - 737. 18. 2020. http://dx.doi.org/10.1016/j.omtm.2020.07.012 . 10.1016/j.omtm.2020.07.012 . published Molecular Therapy - Methods & Clinical Development

Trehalose alleviates the phenotype of Machado–Joseph disease mouse models

Santana, Magda M.; Paixão, Susana; Cunha-Santos, Janete; Silva, Teresa Pereira; Trevino-Garcia, Allyson; Gaspar, Laetitia S.; Nóbrega, Clévio; et al, Journal of Translational Medicine. 1. 18. 2020. http://dx.doi.org/10.1186/s12967-020-02302-2 . 10.1186/s12967-020-02302-2 . published Journal of Translational Medicine

The importance of determining circadian parameters in pharmacological studies

Gaspar, Laetitia S.; Álvaro, Ana Rita; Carmo-Silva, Sara; Mendes, Alexandrina Ferreira; Relógio, Angela; Cavadas, Cláudia, British Journal of Pharmacology. 2827 - 2847. 16. 176. 2019. http://dx.doi.org/10.1111/bph.14712 . 10.1111/bph.14712 . published British Journal of Pharmacology

Obstructive Sleep Apnea and Hallmarks of Aging

Gaspar, Laetitia S.; Álvaro, Ana Rita; Moita, Joaquim; Cavadas, Cláudia, Trends in Molecular Medicine. 675 - 692. 8. 23. 2017. http://dx.doi.org/10.1016/j.molmed.2017.06.006 . 10.1016/j.molmed.2017.06.006 . Trends in Molecular Medicine

All projects

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Information of exclusive responsibility of the researcher 19-05-2024 , from platform CIÊNCIAVITAE.

2024 - 2029

The European Rare Diseases Research Alliance (ERDERA)

-

2024/01 - 2029/12

GeneT

101059981

2023/01 - 2025/12

CInTech

C644865576-00000005

Post-doc

2022/06 - 2023

Science also sleeps: raising awareness about good (and bad) sleep habits

SaS

Universidade de Coimbra Instituto de Investigação Interdisciplinar; Universidade de Coimbra Centro de Estudos Interdisciplinares do Século XX

Funders: Universidade de Coimbra Instituto de Investigação Interdisciplinar

2022/11 - 2023/07

BDforMJD

CENTRO-01-0145-FEDER-181240

2022/10 - 2023/10

OSAscreener

NA

2022/02/01 - 2023/01/31

Sleep2BeHappy

Integration into Research Grant Fellow

Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal

Funders: ResMed Foundation

2021/02/01 - 2022/01/31

Sleep4All

Integration into Research Grant Fellow

Centro de Neurociências e Biologia Celular, Universidade de Coimbra, Portugal

Funders: ResMed Foundation

2018/07/06 - 2021/07/05

A detecção precoce da Apneia do Sono como uma nova estratégia para atrasar o envelhecimento

PTDC/MEC-MCI/29002/2017

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

2018/07 - 2022/10

NoOSAnoAGING

POCI-01-0145-FEDER-029002

PhD Student Fellow

2018/03 - 2019/03

SleepApneaID

CENTRO-01-0246-FEDER-000017

Researcher

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Inov C 2020; Centro 2020

2016/12/01 - 2017/12/31

ESMI: European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative

JPCOFUND/0001/2015

Research Fellow

Universidade de Coimbra Centro de Neurociências e Biologia Celular

Funders: Fundação para a Ciência e a Tecnologia

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